Human/Mouse/Rat SOX2 Antibody Summary
Gly135-Met317
Accession # P48431
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Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Scientific Data

Detection of Human, Mouse, and Rat SOX2 by Western Blot. Western blot shows lysates of D3 mouse embryonic stem cell line, NTera-2 human testicular embryonic carcinoma cell line, F9 mouse teratocarcinoma stem cells, and rat cortical stem cells. PVDF membrane was probed with 1 µg/mL of Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF017). A specific band was detected for SOX2 at approximately 36 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 1.

Detection of SOX2-regulated Genes by Chromatin Immunoprecipitation. BG01V human embryonic stem cells were fixed using formaldehyde, resuspended in lysis buffer, and sonicated to shear chromatin. SOX2/DNA complexes were immunoprecipitated using 5 µg Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) or control antibody (AB-108-C) for 15 minutes in an ultrasonic bath, followed by Biotinylated Anti-Goat IgG Secondary Antibody (BAF109). Immunocomplexes were captured using 50 µL of MagCellect Streptavidin Ferrofluid (MAG999) and DNA was purified using chelating resin solution. Thenanogpromoter was detected by standard PCR.

SOX2 in Mouse Cortical Stem Cells. SOX2 was detected in immersion fixed undifferentiated mouse cortical stem cells using Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; (NL001) and counterstained with DAPI (blue). Nestin was also detected in stem cells using Mouse Anti-Mouse/Rat Nestin Monoclonal Antibody (MAB2736) and co-stained using the NorthernLights™ 493-conjugated Anti-Mouse IgG Secondary Antibody (green; NL009). Specific staining of SOX2 was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips.

SOX2 in Rat Cortical Stem Cells. SOX2 was detected in immersion fixed undifferentiated rat cortical stem cells using Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Nestin was also detected using Mouse Anti-Mouse/Rat Nestin Monoclonal Antibody (MAB2736) and stained using the NorthernLights™ 493-conjugated Anti-Mouse IgG Secondary Antibody (green; NL009). Specific staining of SOX2 was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips.

Detection of Human SOX2 by Simple WesternTM. Simple Western lane view shows lysates of BG01V human embryonic stem cells and NTera-2 human testicular embryonic carcinoma cell line, loaded at 0.2 mg/mL. A specific band was detected for SOX2 at approximately 53 kDa (as indicated) using 5 µg/mL of Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

SOX2 in ADLF1 and FAB2 Stem Cell Lines. SOX2 was detected in immersion fixed ADLF1 (top panel) and FAB2 (bottom panel) induced pluripotent stem cell lines using Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) at 10 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to nuclei. View our protocol for Fluorescent ICC Staining of Stem Cells on Coverslips.

Detection of SOX2 in glioblastoma. SOX2 was detected in immersion fixed paraffin-embedded sections of glioblastoma using Goat Anti-Human/Mouse/Rat SOX2 Antigen Affinity-purified Polyclonal Antibody (Catalog # AF2018) at 3 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (Catalog # VC004). Before incubation with the primary antibody, tissue was subjected to heat-induced epitope retrieval using VisUCyte Antigen Retrieval Reagent-Basic (Catalog # VCTS021). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to nuclei in cancer cells. View our protocol for IHC Staining with VisUCyte HRP Polymer Detection Reagents.
Reconstitution Calculator
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: SOX2
SOX2 belongs to the SOX (SRY-like HMG box) family of transcription factors with diverse roles in development. SOX2 functions in specifying the first three lineages present at implantation and in regulating proliferation and differentiation in the developing peripheral nervous system (1-5).
- Graham, V. et al. (2003) Neuron 39:749.
- Avilion, A.A. et al. (2003) Genes Dev. 17:126.
- Kishi, M. et al. (2000) Development 127:791.
- Yuan, H. et al. (1995) Genes Dev. 9:2635.
- Uwanogho, D. et al. (1995) Mech. Dev. 49:23.
- Stevanovic, M. (2003) Mol. Biol. Rep. 30:127.
Product Datasheets
Citations for Human/Mouse/Rat SOX2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
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Citations: Showing 1 - 10
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Ubiquitination and deubiquitination of 4E-T regulate neural progenitor cell maintenance and neurogenesis by controlling P-body formation
Authors: S Kedia, MR Aghanoori, KML Burns, M Subha, L Williams, P Wen, D Kopp, SL Erickson, EM Harvey, X Chen, M Hua, JU Perez, F Ishraque, G Yang
Oncogene, 2022;40(2):111070.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Effect of DHA on the quality of In�vitro produced bovine embryos
Authors: S Janati Idr, V Slezec-Fri, D Le Bourhis, L Le Berre, T Joly, S Buff, A Desmarchai, L Schibler, P Salvetti, S Elis
Theriogenology, 2022;187(0):102-111.
Species: Bovine
Sample Types: Embryos
Applications: IHC -
Retinoic acid signaling mediates peripheral cone photoreceptor survival in a mouse model of retina degeneration
Authors: R Amamoto, GK Wallick, CL Cepko
Elife, 2022;11(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
8C-like cells capture the human zygotic genome activation program in�vitro
Authors: J Taubenschm, M Rostovskay, F Santos, S Ljung, R Argelaguet, F Krueger, J Nichols, W Reik
Cell Stem Cell, 2022;29(3):449-459.e6.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Paraxial mesoderm organoids model development of human somites
Authors: C Budjan, S Liu, A Ranga, S Gayen, O Pourquié, S Hormoz
Elife, 2022;11(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC/IF -
Generation of an integration-free induced pluripotent stem cell line (LZUSHI001-A) from an epileptic patient with DGKG mutation
Authors: YQ Liu, TW Ling, HY Wang, YH Yang, WJ Song, TC Wang
Stem Cell Research, 2022;61(0):102768.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Aberrant upregulation of the glycolytic enzyme PFKFB3 in CLN7 neuronal ceroid lipofuscinosis
Authors: I Lopez-Fabu, M Garcia-Mac, C Buondelmon, O Burmistrov, N Bonora, P Alonso-Bat, B Morant-Fer, C Vicente-Gu, D Jimenez-Bl, R Quintana-C, E Fernandez, J Llop, P Ramos-Cabr, A Sharaireh, M Guevara-Fe, L Fitzpatric, CD Thompton, TR McKay, S Storch, DL Medina, SE Mole, PO Fedichev, A Almeida, JP Bolaños
Nature Communications, 2022;13(1):536.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Human distal lung maps and lineage hierarchies reveal a bipotent progenitor
Authors: P Kadur Laks, V Sontake, A Tata, Y Kobayashi, L Macadlo, K Okuda, AS Conchola, S Nakano, S Gregory, LA Miller, JR Spence, JF Engelhardt, RC Boucher, JR Rock, SH Randell, PR Tata
Nature, 2022;604(7904):111-119.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
L-Thyroxine Improves Vestibular Compensation in a Rat Model of Acute Peripheral Vestibulopathy: Cellular and Behavioral Aspects
Authors: G Rastoldo, E Marouane, N El-Mahmoud, D Péricat, I Watabe, A Lapotre, A Tonetto, A López-Juár, A El-Ahmadi, P Caron, ME Fraysse, C Chabbert, A Zwergal, B Tighilet
Cells, 2022;11(4):.
Species: Rat
Sample Types: Whole Tissue
Applications: IHC -
Amniogenesis occurs in two independent waves in primates
Authors: M Rostovskay, S Andrews, W Reik, PJ Rugg-Gunn
Cell Stem Cell, 2022;29(5):744-759.e6.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Heme Oxygenase-1 Protects Hair Cells From Gentamicin-Induced Death
Authors: Y Yang, X Chen, K Tian, C Tian, L Chen, W Mi, Q Li, J Qiu, Y Lin, D Zha
Frontiers in Cellular Neuroscience, 2022;16(0):783346.
Species: Rat
Sample Types: Whole Tissue
Applications: IHC -
Cranial irradiation-induced impairment of axonal transport and sexual function in male rats and imaging of the olfactory pathway by MRI
Authors: Q Li, H Dai, F Ran, Y Luo, J Gao, A Deng, N Xu, C Liao, J Yang
Neurotoxicology, 2022;0(0):.
Species: Rat
Sample Types: Tissue Homogenates
Applications: Western Blot -
SOX2 mediates metabolic reprogramming of prostate cancer cells
Authors: L de Wet, A Williams, M Gillard, S Kregel, S Lamperis, LC Gutgesell, JE Vellky, R Brown, K Conger, GP Paner, H Wang, EE Platz, AM De Marzo, P Mu, JL Coloff, RZ Szmulewitz, DJ Vander Gri
Oncogene, 2022;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Generation of an induced pluripotent stem cell line (DHMCi008-A) from an individual with TUBA1A tubulinopathy
Authors: J Schröter, H Syring, G Göhring, S Kölker, T Opladen, GF Hoffmann, S Syrbe, S Jung-Klawi
Stem Cell Research, 2022;62(0):102818.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of a human induced pluripotent stem cell line (LZUSHi002-A) from a MADD patient with ETFDH mutation
Authors: Y Li, Y Li, H Liu, L Cheng, H Ma, X Xu, N Zhang
Stem Cell Research, 2022;64(0):102914.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
beta2-microglobulin maintains glioblastoma stem cells and induces M2-like polarization of tumor-associated macrophages
Authors: D Li, Q Zhang, L Li, K Chen, J Yang, D Dixit, RC Gimple, S Ci, C Lu, L Hu, J Gao, D Shan, Y Li, J Zhang, ZM Shi, D Gu, W Yuan, Q Wu, K Yang, L Zhao, Z Qiu, D Lv, W Gao, H Yang, F Lin, Q Wang, J Man, C Li, W Tao, S Agnihotri, X Qian, Y Shi, Y You, N Zhang, JN Rich, X Wang
Oncogene, 2022;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SOX transcription factors direct TCF-independent WNT/beta-catenin responsive transcription to govern cell fate in human pluripotent stem cells
Authors: S Mukherjee, DM Luedeke, L McCoy, M Iwafuchi, AM Zorn
Cell Reports, 2022;40(8):111247.
Species: Human
Sample Types: Whole Cells
Applications: IF -
Immediate protein expression from exogenous mRNAs in embryonic brain
Authors: M Naruse, T Saito
Scientific Reports, 2022;12(1):17145.
Species: Murine
Sample Types: Whole Tissue
Applications: IHC -
Non-coding de novo mutations in chromatin interactions are implicated in autism spectrum disorder
Authors: IB Kim, T Lee, J Lee, J Kim, S Lee, IG Koh, JH Kim, JY An, H Lee, WK Kim, YS Ju, Y Cho, SJ Yu, SA Kim, M Oh, DW Han, E Kim, JK Choi, HJ Yoo, JH Lee
Oncogene, 2022;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Progesterone Receptor Modulates Extraembryonic Mesoderm and Cardiac Progenitor Specification during Mouse Gastrulation
Authors: AM Drozd, L Mariani, X Guo, V Goitea, NA Menezes, E Ferretti
International Journal of Molecular Sciences, 2022;23(18):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC/IF -
Functional Deficits of 5�FAD Neural Stem Cells Are Ameliorated by Glutathione Peroxidase 4
Authors: NJ Dar, R Na, Q Ran
Cells, 2022;11(11):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
CHD4 mediates SOX2 transcription through TRPS1 in luminal breast cancer
Authors: J Zhang, X Lv, B Wei, X Gong, L Chen
Cellular Signalling, 2022;100(0):110464.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Neurogenesis of Subventricular Zone Progenitors in the Premature Cortex of Ferrets Facilitated by Neonatal Valproic Acid Exposure
Authors: K Sawada
International Journal of Molecular Sciences, 2022;23(9):.
Species: Ferret
Sample Types: Whole Tissue
Applications: IHC -
Lgr5+ cells are required and dynamically participate in olfactory epithelium regeneration: a revisiting shows Lgr5 expression in multiple cell lineages
Authors: W Ren, Z Ma, L Wang, X Feng, H Yu, Y Yu
Theranostics, 2022;12(13):5631-5644.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Global Transcriptional Analyses of the Wnt-Induced Development of Neural Stem Cells from Human Pluripotent Stem Cells
Authors: BC Liu, FY Liu, XY Gao, YL Chen, QQ Meng, YL Song, XH Li, SQ Bao
International Journal of Molecular Sciences, 2021;22(14):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Nucleocytoplasmic transport of the RNA-binding protein CELF2 regulates neural stem cell fates
Authors: MJ MacPherson, SL Erickson, D Kopp, P Wen, MR Aghanoori, S Kedia, KML Burns, A Vitobello, F Tran Mau-T, Q Thomas, NB Gold, W Brucker, L Amlie-Wolf, KW Gripp, O Bodamer, L Faivre, M Muona, L Menzies, J Baptista, K Guegan, A Male, XC Wei, G He, Q Long, AM Innes, G Yang
Cell Reports, 2021;35(10):109226.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC -
Principles of signaling pathway modulation for enhancing human naive pluripotency induction
Authors: J Bayerl, M Ayyash, T Shani, YS Manor, O Gafni, R Massarwa, Y Kalma, A Aguilera-C, M Zerbib, H Amir, D Sheban, S Geula, N Mor, L Weinberger, S Naveh Tass, V Krupalnik, B Oldak, N Livnat, S Tarazi, S Tawil, E Wildschutz, S Ashouokhi, L Lasman, V Rotter, S Hanna, D Ben-Yosef, N Novershter, S Viukov, JH Hanna
Cell Stem Cell, 2021;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Hypothalamic Rax+ tanycytes contribute to tissue repair and tumorigenesis upon oncogene activation in mice
Authors: W Mu, S Li, J Xu, X Guo, H Wu, Z Chen, L Qiao, G Helfer, F Lu, C Liu, QF Wu
Nature Communications, 2021;12(1):2288.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Differentiated glioblastoma cells accelerate tumor progression by shaping the tumor microenvironment via CCN1-mediated macrophage infiltration
Authors: A Uneda, K Kurozumi, A Fujimura, K Fujii, J Ishida, Y Shimazu, Y Otani, Y Tomita, Y Hattori, Y Matsumoto, N Tsuboi, K Makino, S Hirano, A Kamiya, I Date
Acta neuropathologica communications, 2021;9(1):29.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Cascade diversification directs generation of neuronal diversity in the hypothalamus
Authors: YH Zhang, M Xu, X Shi, XL Sun, W Mu, H Wu, J Wang, S Li, P Su, L Gong, M He, M Yao, QF Wu
Cell Stem Cell, 2021;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Ogt controls neural stem/progenitor cell pool and adult neurogenesis through modulating Notch signaling
Authors: J Chen, X Dong, X Cheng, Q Zhu, J Zhang, Q Li, X Huang, M Wang, L Li, W Guo, B Sun, Q Shu, W Yi, X Li
Cell Reports, 2021;34(13):108905.
Species: Mouse
Sample Types: Cell Lysates
Applications: Immunoprecipitation -
Generation of a common marmoset embryonic stem cell line CMES40-OC harboring a POU5F1 (OCT4)-2A-mCerulean3 knock-in reporter allele
Authors: S Yoshimatsu, R Murakami, T Sato, T Saeki, M Yamamoto, E Sasaki, T Noce, H Okano
Stem Cell Research, 2021;53(0):102308.
Species: Callithrix jacchus (Marmoset)
Sample Types: Whole Cells
Applications: ICC -
Airway basal stem cells generate distinct subpopulations of PNECs
Authors: H Mou, Y Yang, MA Riehs, J Barrios, M Shivaraju, AL Haber, DT Montoro, K Gilmore, EA Haas, B Paunovic, J Rajagopal, SO Vargas, RL Haynes, A Fine, WV Cardoso, X Ai
Cell Reports, 2021;35(3):109011.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
5-hydroxymethylcytosine is dynamically regulated during forebrain organoid development and aberrantly altered in Alzheimer's disease
Authors: JN Kuehner, J Chen, EC Bruggeman, F Wang, Y Li, C Xu, ZT McEachin, Z Li, L Chen, CM Hales, Z Wen, J Yang, B Yao
Cell Reports, 2021;35(4):109042.
Species: Human
Sample Types: Cell Lysates
Applications: Dot Blot -
Generation of excitatory and inhibitory neurons from common progenitors via Notch signaling in the cerebellum
Authors: T Zhang, T Liu, N Mora, J Guegan, M Bertrand, X Contreras, AH Hansen, C Streicher, M Anderle, N Danda, L Tiberi, S Hippenmeye, BA Hassan
Cell Reports, 2021;35(10):109208.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Non-viral derivation of a transgene-free induced pluripotent stem cell line from a male beagle dog
Authors: S Yoshimatsu, K Edamura, Y Yoshii, A Iguchi, H Kondo, H Shibuya, T Sato, S Shiozawa, H Okano
Stem Cell Research, 2021;53(0):102375.
Species: Canine
Sample Types: Whole Cells
Applications: ICC -
Organoid modeling of Zika and herpes simplex virus 1 infections reveals virus-specific responses leading to microcephaly
Authors: V Krenn, C Bosone, TR Burkard, J Spanier, U Kalinke, A Calistri, C Salata, R Rilo Chris, P Pestana Ga, A Mirazimi, JA Knoblich
Cell Stem Cell, 2021;0(0):.
Species: Human
Sample Types: Organoid
Applications: IHC -
Generation of a heterozygous GAPDH-Luciferase human ESC line (HVRDe008-A-1) for in vivo monitoring of stem cells and their differentiated progeny
Authors: D Gerace, KR Boulanger, J Hyoje-Ryu, DA Melton
Stem Cell Research, 2021;53(0):102371.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Establishing an induced pluripotent stem cell line from neonatal common marmoset fibroblasts by an all-in-one episomal vector approach
Authors: S Yoshimatsu, E Qian, T Sato, M Yamamoto, M Ishikawa, H Okano
Stem Cell Research, 2021;53(0):102380.
Species: Marmoset
Sample Types: Whole Cells
Applications: ICC -
An induced pluripotent stem cell line (GZHMCi004-A) derived from a fetus with heterozygous G380R mutation in FGFR3 gene causing achondroplasia
Authors: N Li, SM Lin, Y Li, J Sun, L Zhang, M Chen
Stem Cell Research, 2021;53(0):102322.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Capicua regulates the development of adult-born neurons in the hippocampus
Authors: B Hourigan, SD Balay, G Yee, S Sharma, Q Tan
Scientific Reports, 2021;11(1):11725.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Autologous transplant therapy alleviates motor and depressive behaviors in parkinsonian monkeys
Authors: Y Tao, SC Vermilyea, M Zammit, J Lu, M Olsen, JM Metzger, L Yao, Y Chen, S Phillips, JE Holden, V Bondarenko, WF Block, TE Barnhart, N Schultz-Da, K Brunner, H Simmons, BT Christian, ME Emborg, SC Zhang
Nature Medicine, 2021;0(0):.
Species: Primate - Rhesus macaque
Sample Types: Whole Cells
Applications: ICC -
Evaluation of UBE3A antibodies in mice and human cerebral organoids
Authors: D Sen, Z Drobna, AJ Keung
Scientific Reports, 2021;11(1):6323.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Assessment of auditory and vestibular damage in a mouse model after single and triple blast exposures
Authors: B Mao, Y Wang, T Balasubram, R Urioste, T Wafa, TS Fitzgerald, SJ Haraczy, K Edwards-Ho, ZN Sayyid, D Wilder, VSSS Sajja, Y Wei, P Arun, I Gist, AG Cheng, JB Long, MW Kelley
Hearing research, 2021;407(0):108292.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Generation of an induced pluripotent stem cell line (FDCHi006-A) from a 7-year-old girl with central precocious puberty
Authors: T Fan, J He, Y Wang, J Yu, W Sun
Stem Cell Research, 2021;56(0):102542.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Establishment of an induced pluripotent stem cell line from a female domestic ferret (Mustela putorius furo) with an X chromosome instability
Authors: S Yoshimatsu, R Murakami, M Nakajima, T Sato, H Kawasaki, H Okano
Stem Cell Research, 2021;53(0):102385.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment
Authors: X Dong, L Yang, K Liu, X Ji, C Tang, W Li, L Ma, Y Mei, T Peng, B Feng, Z Wu, Q Tang, Y Gao, K Yan, W Zhou, M Xiong
Cell Reports, 2021;34(9):108802.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
A human three-dimensional neural-perivascular 'assembloid' promotes astrocytic development and enables modeling of SARS-CoV-2 neuropathology
Authors: L Wang, D Sievert, AE Clark, S Lee, H Federman, BD Gastfriend, EV Shusta, SP Palecek, AF Carlin, JG Gleeson
Nature Medicine, 2021;0(0):.
Species: Human
Sample Types: Organoid
Applications: IHC -
Generation and validation of a common marmoset embryonic stem cell line ActiCre-B1 that ubiquitously expresses a tamoxifen-inducible Cre-driver
Authors: S Yoshimatsu, K Ohtsu, T Sato, M Yamamoto, E Sasaki, S Shiozawa, H Okano
Stem Cell Research, 2021;51(0):102164.
Species: Marmoset
Sample Types: Whole Cells
Applications: Flow Cytometry -
A human forebrain organoid model of fragile X syndrome exhibits altered neurogenesis and highlights new treatment strategies
Authors: Y Kang, Y Zhou, Y Li, Y Han, J Xu, W Niu, Z Li, S Liu, H Feng, W Huang, R Duan, T Xu, N Raj, F Zhang, J Dou, C Xu, H Wu, GJ Bassell, ST Warren, EG Allen, P Jin, Z Wen
Nature Neuroscience, 2021;0(0):.
Species: Human
Sample Types: Organoid
Applications: ICC -
Greater epithelial ridge cells are the principal organoid-forming progenitors of the mouse cochlea
Authors: M Kubota, M Scheibinge, TA Jan, S Heller
Cell Reports, 2021;34(3):108646.
Species: Mouse
Sample Types: Organoid
Applications: IHC -
OCT4 cooperates with distinct ATP-dependent chromatin remodelers in na�ve and primed pluripotent states in human
Authors: X Huang, KM Park, P Gontarz, B Zhang, J Pan, Z McKenzie, LA Fischer, C Dong, S Dietmann, X Xing, PV Shliaha, J Yang, D Li, J Ding, T Lungjangwa, M Mitalipova, SA Khan, S Imsoonthor, N Jensen, T Wang, C Kadoch, R Jaenisch, J Wang, TW Theunissen
Nature Communications, 2021;12(1):5123.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Spatiotemporal dynamics of inner ear sensory and non-sensory cells revealed by single-cell transcriptomics
Authors: TA Jan, Y Eltawil, AH Ling, L Chen, DC Ellwanger, S Heller, AG Cheng
Cell Reports, 2021;36(2):109358.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
CD109-GP130 interaction drives glioblastoma stem cell plasticity and chemoresistance through STAT3 activity
Authors: P Filppu, JT Ramanathan, KJ Granberg, E Gucciardo, H Haapasalo, K Lehti, M Nykter, V Le Joncour, P Laakkonen
JCI Insight, 2021;6(9):.
Species: Human
Sample Types: Cell Lysates
Applications: Co-Immunoprecipitation -
MeCP2 controls neural stem cell fate specification through miR-199a-mediated inhibition of BMP-Smad signaling
Authors: H Nakashima, K Tsujimura, K Irie, T Imamura, CA Trujillo, M Ishizu, M Uesaka, M Pan, H Noguchi, K Okada, K Aoyagi, T Andoh-Noda, H Okano, AR Muotri, K Nakashima
Cell Reports, 2021;35(7):109124.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Lineage-tracing and translatomic analysis of damage-inducible mitotic cochlear progenitors identifies candidate genes regulating regeneration
Authors: T Udagawa, PJ Atkinson, B Milon, JM Abitbol, Y Song, M Sperber, E Huarcaya N, M Scheibinge, R Elkon, R Hertzano, AG Cheng
PloS Biology, 2021;19(11):e3001445.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Dynamic Spatiotemporal Expression Changes in Connexins of the Developing Primate's Cochlea
Authors: M Hosoya, M Fujioka, AY Murayama, K Ogawa, H Okano, H Ozawa
Genes, 2021;12(7):.
Species: Marmoset
Sample Types: Whole Tissue
Applications: IHC -
Functional human gastrointestinal organoids can be engineered from three primary germ layers derived separately from pluripotent stem cells
Authors: AK Eicher, DO Kechele, N Sundaram, HM Berns, HM Poling, LE Haines, JG Sanchez, K Kishimoto, M Krishnamur, L Han, AM Zorn, MA Helmrath, JM Wells
Cell Stem Cell, 2021;0(0):.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
A predominant enhancer co-amplified with the SOX2 oncogene is necessary and sufficient for its expression in squamous cancer
Authors: Y Liu, Z Wu, J Zhou, DKA Ramadurai, KL Mortenson, E Aguilera-J, Y Yan, X Yang, AM Taylor, KE Varley, J Gertz, PS Choi, AD Cherniack, X Chen, AJ Bass, SD Bailey, X Zhang
Nature Communications, 2021;12(1):7139.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Generation of a gene-corrected isogenic iPSC line (AHQUi001-A-1) from a patient with familial hypertriglyceridemia (FHTG) carrying a heterozygous p.C310R (c.928�T�>�C) mutation in LPL gene using CRISPR/Cas9
Authors: X Sun, X Zhou, B Dong, C Wang, X Xiao, Y Wang
Stem Cell Research, 2021;52(0):102230.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Andrographolide promotes hippocampal neurogenesis and spatial memory in the APPswe/PS1deltaE9 mouse model of Alzheimer's disease
Authors: SB Arredondo, DT Reyes, A Herrera-So, MD Mardones, NC Inestrosa, L Varela-Nal
Scientific Reports, 2021;11(1):22904.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
ApoE-Isoform-Dependent SARS-CoV-2 Neurotropism and Cellular Response
Authors: C Wang, M Zhang, G Garcia, E Tian, Q Cui, X Chen, G Sun, J Wang, V Arumugaswa, Y Shi
Cell Stem Cell, 2021;28(2):331-342.e5.
Species: Human
Sample Types: Organoid
Applications: ICC -
An induced pluripotent stem cell line (GZHMCi003-A) derived from a fetus with exon 3 heterozygous deletion in RUNX2 gene causing cleidocranial dysplasia
Authors: M Chen, SM Lin, N Li, Y Li, Y Li, L Zhang
Stem Cell Research, 2021;51(0):102166.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Fetal growth restriction impairs hippocampal neurogenesis and cognition via Tet1 in offspring
Authors: W Chen, N Liu, S Shen, W Zhu, J Qiao, S Chang, J Dong, M Bai, L Ma, S Wang, W Jia, X Guo, A Li, J Xi, C Jiang, J Kang
Cell Reports, 2021;37(5):109912.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Differentiation of mouse fetal lung alveolar progenitors in serum-free organotypic cultures
Authors: K Gkatzis, P Panza, S Peruzzo, DY Stainier
Elife, 2021;10(0):.
Species: Mouse
Sample Types: Organoids
Applications: IHC -
Selective deletion of human leukocyte antigens protects stem cell-derived islets from immune rejection
Authors: AV Parent, G Faleo, J Chavez, M Saxton, DI Berrios, NR Kerper, Q Tang, M Hebrok
Cell Reports, 2021;36(7):109538.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Embryonic and Neonatal Mouse Cochleae Are Susceptible to Zika Virus Infection
Authors: V Munnamalai, NH Sammudin, CA Young, A Thawani, RJ Kuhn, DM Fekete
Viruses, 2021;13(9):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
WAPL maintains a cohesin loading cycle to preserve cell-type-specific distal gene regulation
Authors: NQ Liu, M Maresca, T van den Br, L Braccioli, MMGA Schijns, H Teunissen, BG Bruneau, EP Nora, E de Wit
Nature Genetics, 2020;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Medulloblastoma Arises from the Persistence of a Rare and Transient Sox2+ Granule Neuron Precursor
Authors: HJ Selvadurai, E Luis, K Desai, X Lan, MC Vladoiu, O Whitley, C Galvin, RJ Vanner, L Lee, H Whetstone, M Kushida, T Nowakowski, P Diamandis, C Hawkins, G Bader, A Kriegstein, MD Taylor, PB Dirks
Cell Rep, 2020;31(2):107511.
Species: Mouse
Sample Types: Embryo
Applications: IF -
Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1
Authors: J Romero-Poz, G Figlia, O Kaya, A Martin-Vil, AA Teleman
Cell Rep, 2020;31(2):107504.
Species: Mouse
Sample Types: Neural Stem Cells
Applications: IF -
Generation of a male common marmoset embryonic stem cell line DSY127-BV8VT1 carrying double reporters specific for the germ cell linage using the CRISPR-Cas9 and PiggyBac transposase systems
Authors: S Yoshimatsu, T Sato, M Yamamoto, E Sasaki, M Nakajima, M Nakamura, S Shiozawa, T Noce, H Okano
Stem Cell Res, 2020;44(0):101740.
Species: Callithrix jacchus (Marmoset)
Sample Types: Whole Cells
Applications: ICC -
An induced pluripotent stem cell line (SHEHi002-A (5426))from a patient of long QT syndrome type 8 with c.2573G>A mutation in the gene CACNA1C
Authors: HM Zhou, XQ Zhou, JZ Lu, WW Jia, JH Kang
Stem Cell Res, 2020;43(0):101731.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Identification of ALPPL2 as a Naive Pluripotent State-Specific Surface Protein Essential for Human Naive Pluripotency Regulation
Authors: Y Bi, Z Tu, Y Zhang, P Yang, M Guo, X Zhu, C Zhao, J Zhou, H Wang, Y Wang, S Gao
Cell Rep, 2020;30(11):3917-3931.e5.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Efficient in Utero Gene Transfer to the Mammalian Inner Ears by the Synthetic Adeno-Associated Viral Vector Anc80L65
Authors: CJ Hu, YC Lu, YH Tsai, HY Cheng, H Takeda, CY Huang, R Xiao, CJ Hsu, JW Tsai, LH Vandenberg, CC Wu, YF Cheng
Mol Ther Methods Clin Dev, 2020;18(0):493-500.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Multiscale 3D phenotyping of human cerebral organoids
Authors: A Albanese, JM Swaney, DH Yun, NB Evans, JM Antonucci, S Velasco, CH Sohn, P Arlotta, L Gehrke, K Chung
Scientific Reports, 2020;10(1):21487.
Species: Aedes albopictus (mosquito)
Sample Types: Organoid
Applications: ICC -
Human Lung Stem Cell-Based Alveolospheres Provide Insights into SARS-CoV-2-Mediated Interferon Responses and Pneumocyte Dysfunction
Authors: H Katsura, V Sontake, A Tata, Y Kobayashi, CE Edwards, BE Heaton, A Konkimalla, T Asakura, Y Mikami, EJ Fritch, PJ Lee, NS Heaton, RC Boucher, SH Randell, RS Baric, PR Tata
Cell Stem Cell, 2020;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency
Authors: DA Skelly, A Czechanski, C Byers, S Aydin, C Spruce, C Olivier, K Choi, DM Gatti, N Raghupathy, GR Keele, A Stanton, M Vincent, S Dion, I Greenstein, M Pankratz, DK Porter, W Martin, C O'Connor, W Qin, AH Harrill, T Choi, GA Churchill, SC Munger, CL Baker, LG Reinholdt
Cell Stem Cell, 2020;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Establishment of human induced pluripotent stem cell line (CPGHi002-A) from a 10-month-old female patient with DDOD syndrome carrying a heterozygous c.1516 C�>�T mutation in ATP6V1B2
Authors: X Gao, SW Qiu, ML Feng, SS Huang, DY Kang, MY Han, P Dai, YY Yuan
Stem Cell Res, 2020;48(0):101986.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
ROBO2 signaling in lung development regulates SOX2/SOX9 balance, branching morphogenesis and is dysregulated in nitrofen-induced congenital diaphragmatic hernia
Authors: AN Gonçalves, J Correia-Pi, C Nogueira-S
Respir Res, 2020;21(1):302.
Species: Rat
Sample Types: Cell Lysates
Applications: Western Blot -
Efficient in Utero Gene Transfer to the Mammalian Inner Ears by the Synthetic Adeno-Associated Viral Vector Anc80L65
Authors: CJ Hu, YC Lu, YH Tsai, HY Cheng, H Takeda, CY Huang, R Xiao, CJ Hsu, JW Tsai, LH Vandenberg, CC Wu, YF Cheng
Mol Ther Methods Clin Dev, 2020;18(0):493-500.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
TAZ Represses the Neuronal Commitment of Neural Stem Cells
Authors: N Robledinos, M Escoll, KL Guan, A Cuadrado
Cells, 2020;9(10):.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
SATB2 drives glioblastoma growth by recruiting CBP to promote FOXM1 expression in glioma stem cells
Authors: W Tao, A Zhang, K Zhai, Z Huang, H Huang, W Zhou, Q Huang, X Fang, BC Prager, X Wang, Q Wu, AE Sloan, MS Ahluwalia, JD Lathia, JS Yu, JN Rich, S Bao
EMBO Mol Med, 2020;0(0):e12291.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Mapping the Effects of Genetic Variation on Chromatin State and Gene Expression Reveals Loci That Control Ground State Pluripotency
Authors: DA Skelly, A Czechanski, C Byers, S Aydin, C Spruce, C Olivier, K Choi, DM Gatti, N Raghupathy, GR Keele, A Stanton, M Vincent, S Dion, I Greenstein, M Pankratz, DK Porter, W Martin, C O'Connor, W Qin, AH Harrill, T Choi, GA Churchill, SC Munger, CL Baker, LG Reinholdt
Cell Stem Cell, 2020;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC -
LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex
Authors: D Jeong, D Lozano Cas, A Gengathara, K Edwards, A Saghatelya, DR Kaplan, FD Miller, SA Yuzwa
Cell Rep, 2020;33(2):108257.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Reconstruction of Alzheimer's Disease Cell Model In Vitro via Extracted Peripheral Blood Molecular Cells from a Sporadic Patient
Authors: S Liu, Y Zhao, X Su, C Zhou, P Yang, Q Lin, S Li, H Tan, Q Wang, C Wang, Q Wu
Stem Cells International, 2020;2020(0):8897494.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Variation of Human Neural Stem Cells Generating Organizer States In�Vitro before Committing to Cortical Excitatory or Inhibitory Neuronal Fates
Authors: N Micali, SK Kim, M Diaz-Busta, G Stein-O'Br, S Seo, JH Shin, BG Rash, S Ma, Y Wang, NA Olivares, JI Arellano, KR Maynard, EJ Fertig, AJ Cross, RW Bürli, NJ Brandon, DR Weinberger, JG Chenoweth, DJ Hoeppner, N Sestan, P Rakic, C Colantuoni, RD McKay
Cell Rep, 2020;31(5):107599.
Species: Human
Sample Types:
Applications: IF -
Generation of an isogenic gene-corrected iPSC line (PUMCHi001-A-1) from a familial partial lipodystrophy type 2 (FPLD2) patient with a heterozygous R349W mutation in the LMNA gene
Authors: C Xiao, M Yu, J Liu, H Wu, M Deng, Q Zhang, X Xiao
Stem Cell Res, 2020;44(0):101753.
Species: Human
Sample Types: Whole Cells
Applications: Flow Cytometry -
Generation of an induced pluripotent stem cell line (DANi-011A) from a Parkinson's disease patient with a LRRK2 p.G2019S mutation
Authors: M Chen, M Maimaitili, SH Buchholdt, UB Jensen, F Febbraro, M Denham
Stem Cell Res, 2020;45(0):101781.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Generation of an iPSC line (CHWi001-A) from peripheral blood mononuclear cells in a patient with intellectual disability and haploinsufficiency of PLPPR4
Authors: R Wan, Q Zhang, H Li, X Xu, S Tang
Stem Cell Res, 2020;45(0):101811.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Hydraulic control of mammalian embryo size and cell fate
Authors: CJ Chan, M Costanzo, T Ruiz-Herre, G Mönke, RJ Petrie, M Bergert, A Diz-Muñoz, L Mahadevan, T Hiiragi
Nature, 2019;0(0):.
Species: Mouse
Sample Types: Embryo
Applications: IHC -
Direct Reprogramming of Human Neurons Identifies MARCKSL1 as a Pathogenic Mediator of Valproic Acid-Induced Teratogenicity
Authors: S Chanda, CE Ang, QY Lee, M Ghebrial, D Haag, Y Shibuya, M Wernig, TC Südhof
Cell Stem Cell, 2019;25(1):103-119.e6.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
O-GlcNAc transferase activates stem-like cell potential in hepatocarcinoma through O-GlcNAcylation of eukaryotic initiation factor 4E
Authors: B Cao, M Duan, Y Xing, C Liu, F Yang, Y Li, T Yang, Y Wei, Q Gao, J Jiang
J. Cell. Mol. Med., 2019;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Zika virus infection induces RNAi-mediated antiviral immunity in human neural progenitors and brain organoids
Authors: YP Xu, Y Qiu, B Zhang, G Chen, Q Chen, M Wang, F Mo, J Xu, J Wu, RR Zhang, ML Cheng, NN Zhang, B Lyu, WL Zhu, MH Wu, Q Ye, D Zhang, JH Man, XF Li, J Cui, Z Xu, B Hu, X Zhou, CF Qin
Cell Res., 2019;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Chi3l3 induces oligodendrogenesis in an experimental model of autoimmune neuroinflammation
Authors: SC Starossom, J Campo Garc, T Woelfle, S Romero-Sua, M Olah, F Watanabe, L Cao, A Yeste, JJ Tukker, FJ Quintana, J Imitola, F Witzel, D Schmitz, M Morkel, F Paul, C Infante-Du, SJ Khoury
Nat Commun, 2019;10(1):217.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
The BAF and PRC2 Complex Subunits Dpf2 and Eed Antagonistically Converge on Tbx3 to Control ESC Differentiation
Authors: W Zhang, C Chronis, X Chen, H Zhang, R Spalinskas, M Pardo, L Chen, G Wu, Z Zhu, Y Yu, L Yu, J Choudhary, J Nichols, MM Parast, B Greber, P Sahlén, K Plath
Cell Stem Cell, 2019;24(1):138-152.e8.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
YAP Activity Is Necessary and Sufficient for Basal Progenitor Abundance and Proliferation in the Developing Neocortex
Authors: M Kostic, JTML Paridaen, KR Long, N Kalebic, B Langen, N Grübling, P Wimberger, H Kawasaki, T Namba, WB Huttner
Cell Rep, 2019;27(4):1103-1118.e6.
Species: Ferret
Sample Types: Whole Tissue
Applications: IHC -
Semaphorin-5B Controls Spiral Ganglion Neuron Branch Refinement During Development
Authors: JS Jung, KD Zhang, Z Wang, M McMurray, A Tkaczuk, Y Ogawa, R Hertzano, TM Coate
J. Neurosci., 2019;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Lack of whey acidic protein four disulphide core (WFDC) 2 protease inhibitor causes neonatal death from respiratory failure in mice
Authors: K Nakajima, M Ono, U Radovi?, S Dizdarevi?, SI Tomizawa, K Kuroha, G Naganatsu, I Hoshi, R Matsunaga, T Shirakawa, T Kurosawa, Y Miyazaki, M Seki, Y Suzuki, H Koseki, M Nakamura, T Suda, K Ohbo
Dis Model Mech, 2019;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
Biomanufacturing of organ-specific tissues with high cellular density and embedded vascular channels
Authors: MA Skylar-Sco, SGM Uzel, LL Nam, JH Ahrens, RL Truby, S Damaraju, JA Lewis
Sci Adv, 2019;5(9):eaaw2459.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Single-cell analysis reveals T cell infiltration in old neurogenic niches
Authors: BW Dulken, MT Buckley, P Navarro Ne, N Saligrama, R Cayrol, DS Leeman, BM George, SC Boutet, K Hebestreit, JV Pluvinage, T Wyss-Coray, IL Weissman, H Vogel, MM Davis, A Brunet
Nature, 2019;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
The RNA Helicase DDX6 Controls Cellular Plasticity by Modulating P-Body Homeostasis
Authors: B Di Stefano, EC Luo, C Haggerty, S Aigner, J Charlton, J Brumbaugh, F Ji, I Rabano Jim, KJ Clowers, AJ Huebner, K Clement, I Lipchina, MAC de Kort, A Anselmo, J Pulice, MFM Gerli, H Gu, SP Gygi, RI Sadreyev, A Meissner, GW Yeo, K Hochedling
Cell Stem Cell, 2019;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Epigenomic Profiling Discovers Trans-lineage SOX2 Partnerships Driving Tumor Heterogeneity in Lung Squamous Cell Carcinoma
Authors: T Sato, S Yoo, R Kong, A Sinha, P Chandraman, A Patel, M Fridrikh, O Nagano, T Masuko, MB Beasley, CA Powell, J Zhu, H Watanabe
Cancer Res., 2019;79(24):6084-6100.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Lysine acetyltransferase 8 is involved in cerebral development and syndromic intellectual disability
Authors: L Li, M Ghorbani, M Weisz-Hubs, J Rousseau, I Thiffault, RE Schnur, C Breen, R Oegema, MM Weiss, Q Waisfisz, S Welner, H Kingston, JA Hills, EM Boon, L Basel-Salm, O Konen, H Goldberg-S, L Bazak, S Tzur, J Jin, X Bi, M Bruccoleri, K McWalter, MT Cho, M Scarano, GB Schaefer, SS Brooks, SS Hughes, KLI van Gassen, JM van Hagen, TK Pandita, PB Agrawal, PM Campeau, XJ Yang
J. Clin. Invest., 2019;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Gastrointestinal transcription factors drive lineage-specific developmental programs in organ specification and cancer
Authors: R Francis, H Guo, C Streutker, M Ahmed, T Yung, PB Dirks, HH He, TH Kim
Sci Adv, 2019;5(12):eaax8898.
Species: Mouse
Sample Types: Cell Lysates
Applications: ChIP -
Establishment of induced pluripotent stem cell line (GSPHi001-A) from a 6-year old female with nephrotic syndrome
Authors: X Gao, X Gao, H Zhao, W Cui, M Tan, H Deng
Stem Cell Res, 2019;41(0):101661.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SNAI2 upregulation is associated with an aggressive phenotype in fulvestrant-resistant breast cancer cells and is an indicator of poor response to endocrine therapy in estrogen receptor-positive metastatic breast cancer
Authors: CL Alves, D Elias, MB Lyng, M Bak, HJ Ditzel
Breast Cancer Res., 2018;20(1):60.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
Authors: KA Lazarus, F Hadi, E Zambon, K Bach, MF Santolla, JK Watson, LL Correia, M Das, R Ugur, S Pensa, L Becker, LS Campos, G Ladds, P Liu, GI Evan, FM McCaughan, J Le Quesne, JH Lee, D Calado, WT Khaled
Nat Commun, 2018;9(1):3327.
Species: Human
Sample Types: DNA
Applications: ChIP -
Submucosal Gland Myoepithelial Cells Are Reserve Stem Cells That Can Regenerate Mouse Tracheal Epithelium
Authors: TJ Lynch, PJ Anderson, PG Rotti, SR Tyler, AK Crooke, SH Choi, DT Montoro, CL Silverman, W Shahin, R Zhao, CW Jensen-Cod, A Adamcakova, TIA Evans, W Xie, Y Zhang, H Mou, BP Herring, PS Thorne, J Rajagopal, C Yeaman, KR Parekh, JF Engelhardt
Cell Stem Cell, 2018;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
NMDA receptor signaling is important for neural tube formation and for preventing antiepileptic drug-induced neural tube defects
Authors: EB Sequerra, R Goyal, PA Castro, JB Levin, LN Borodinsky
J. Neurosci., 2018;0(0):.
Species: Xenopus
Sample Types: Whole Tissue
Applications: IHC -
NADsupplementation normalizes key Alzheimer's features and DNA damage responses in a new AD mouse model with introduced DNA repair deficiency
Authors: Y Hou, S Lautrup, S Cordonnier, Y Wang, DL Croteau, E Zavala, Y Zhang, K Moritoh, JF O'Connell, BA Baptiste, TV Stevnsner, MP Mattson, VA Bohr
Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Transcriptional repressor GATA binding 1-mediated repression of SRY-box 2 expression suppresses cancer stem cell functions and tumor initiation
Authors: X Gong, W Liu, L Wu, Z Ma, Y Wang, S Yu, J Zhang, H Xie, G Wei, F Ma, L Lu, L Chen
J. Biol. Chem., 2018;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Generation of a human Juvenile myelomonocytic leukemia iPSC line, CHOPi001-A, with a mutation in CBL
Authors: AL Gagne, JA Maguire, S Gandre-Bab, ST Chou, SK Tasian, ML Loh, MJ Weiss, P Gadue, DL French
Stem Cell Res, 2018;31(0):157-160.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Selective enrichment of CD133+/SOX2+ glioblastoma stem cells via adherent culture
Authors: K Lv, Z Chen, X Zhang, Q Zhang, L Liu
Oncol Lett, 2018;16(4):4567-4576.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Complementary expression of calcium binding proteins delineates the functional organization of the locomotor network
Authors: EM Berg, M Bertuzzi, K Ampatzis
Brain Struct Funct, 2018;0(0):.
Species: Zebrafish
Sample Types: Whole Tissue
Applications: IHC -
Central and Peripheral Nervous System Progenitors Derived from Human Pluripotent Stem Cells Reveal a Unique Temporal and Cell-Type Specific Expression of PMCAs
Authors: M Chen, SH Laursen, M Habekost, CH Knudsen, SH Buchholdt, J Huang, F Xu, X Liu, L Bolund, Y Luo, P Nissen, F Febbraro, M Denham
Front Cell Dev Biol, 2018;6(0):5.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
Authors: PR Tata, RD Chow, SV Saladi, A Tata, A Konkimalla, A Bara, D Montoro, LP Hariri, AR Shih, M Mino-Kenud, H Mou, S Kimura, LW Ellisen, J Rajagopal
Dev. Cell, 2018;44(6):679-693.e5.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-Fr -
Generation of Spinocerebellar Ataxia Type 2 induced pluripotent stem cell lines, CHOPi002-A and CHOPi003-A, from patients with abnormal CAG repeats in the coding region of the ATXN2 gene
Authors: JA Maguire, AL Gagne, P Gonzalez-A, BL Davidson, V Shakkottai, P Gadue, DL French
Stem Cell Res, 2018;34(0):101361.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
BMP and WNT signalling cooperate through LEF1 in the neuronal specification of adult hippocampal neural stem and progenitor cells
Authors: T Armenteros, Z Andreu, R Hortigüela, DC Lie, H Mira
Sci Rep, 2018;8(1):9241.
Species: Rat
Sample Types: Whole Cells
Applications: ICC -
Treatment of Human Glioblastoma with a Live Attenuated Zika Virus Vaccine Candidate
Authors: Q Chen, J Wu, Q Ye, F Ma, Q Zhu, Y Wu, C Shan, X Xie, D Li, X Zhan, C Li, XF Li, X Qin, T Zhao, H Wu, PY Shi, J Man, CF Qin
MBio, 2018;9(5):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Generation of seven induced pluripotent stem cell lines from neonates of different ethnic backgrounds
Authors: Y Yin, AJ Petersen, C Soref, WD Richards, T Ludwig, S Taapken, E Berndt, SC Zhang, A Bhattachar
Stem Cell Res, 2018;34(0):101365.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Reduced expression of the murine HLA-G homolog Qa-2 is associated with malignancy, epithelial-mesenchymal transition and stemness in breast cancer cells
Authors: IL da Silva, L Montero-Mo, E Martín-Vil, J Martin-Pér, B Sainz, J Renart, R Toscano Si, É Soares Vel, C Salviano T, MC de Oliveir, E Ferreira, M Quintanill
Sci Rep, 2017;7(1):6276.
Species: Mouse
Sample Types: Cell Lysates
Applications: Western Blot -
Colitis promotes neuronal differentiation of Sox2+ and PLP1+ enteric cells
Authors: J Belkind-Ge, HK Graham, J Reynolds, R Hotta, N Nagy, L Cheng, M Kamionek, HN Shi, CM Aherne, AM Goldstein
Sci Rep, 2017;7(1):2525.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Folate receptor alpha is necessary for neural plate cell apical constriction during Xenopus neural tube formation
Authors: OA Balashova, O Visina, LN Borodinsky
Development, 2017;0(0):.
Species: Xenopus
Sample Types: Whole Tissue
Applications: IHC-P -
CryoPause: A New Method to Immediately Initiate Experiments after Cryopreservation of Pluripotent Stem Cells
Authors: KG Wong, SD Ryan, K Ramnarine, SA Rosen, SE Mann, A Kulick, E De Stanchi, FJ Müller, TJ Kacmarczyk, C Zhang, D Betel, MJ Tomishima
Stem Cell Reports, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Peptide-Based Scaffolds Support Human Cortical Progenitor Graft Integration to Reduce Atrophy and Promote Functional Repair in a Model of Stroke
Authors: FA Somaa, TY Wang, JC Niclis, KF Bruggeman, JA Kauhausen, H Guo, S McDougall, RJ Williams, DR Nisbet, LH Thompson, CL Parish
Cell Rep, 2017;20(8):1964-1977.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Evidence of functional duplicity of Nestin expression in the adult mouse midbrain
Authors: P Farzanehfa, SS Lu, A Dey, D Musiienko, H Baagil, MK Horne, TD Aumann
Stem Cell Res, 2017;19(0):82-93.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Sin3a regulates epithelial progenitor cell fate during lung development
Authors: C Yao, G Carraro, B Konda, X Guan, T Mizuno, N Chiba, M Kostelny, A Kurkciyan, G David, JL McQualter, BR Stripp
Development, 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Generation of a multipurpose Prdm16 allele by targeted trapping
Authors: A Strassman, F Schnütgen, Q Dai, JC Jones, AC Gomez, L Pitstick, NE Holton, R Moskal, ER Leslie, H von Melchn, DR Beier, BC Bjork
Dis Model Mech, 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Long-Distance Axonal Growth and Protracted Functional Maturation of Neurons Derived From Human Induced Pluripotent Stem Cells After Intracerebral Transplantation
Authors: JC Niclis, C Turner, J Durnall, S McDougal, JA Kauhausen, B Leaw, M Dottori, CL Parish, LH Thompson
Stem Cells Transl Med, 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Human neural progenitors derived from integration-free iPSCs for SCI therapy
Authors: Y Liu, Y Zheng, S Li, H Xue, K Schmitt, GW Hergenroed, J Wu, Y Zhang, DH Kim, Q Cao
Stem Cell Res, 2017;19(0):55-64.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Directed transdifferentiation of M�ller glial cells to photoreceptors using the sonic hedgehog signaling pathway agonist purmorphamine
Authors: D Gu, S Wang, S Zhang, P Zhang, G Zhou
Mol Med Rep, 2017;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: ICC -
Synaptic regulator ?-synuclein in dopaminergic fibers is essentially required for the maintenance of subependymal neural stem cells
Authors: A Perez-Vill, M Salomé Sir, G Belenguer, R Soriano-Ca, A Belén Muño, J Villadiego, D Alarcón-Ar, FN Soria, B Dehay, E Bezard, M Vila, A Bortolozzi, J José Toled, F Pérez-Sánc, I Fariñas
J. Neurosci., 2017;0(0):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Sox2 regulates M�ller glia reprogramming and proliferation in the regenerating zebrafish retina via Lin28 and Ascl1a
Authors: RA Gorsuch, M Lahne, CE Yarka, ME Petravick, J Li, DR Hyde
Exp. Eye Res., 2017;0(0):.
Species: Fish
Sample Types: Whole Tissue
Applications: IHC -
Succession of transiently active tumor-initiating cell clones in human pancreatic cancer xenografts
Authors: CR Ball, F Oppel, KR Ehrenberg, TD Dubash, SM Dieter, CM Hoffmann, U Abel, F Herbst, M Koch, J Werner, F Bergmann, N Ishaque, M Schmidt, C von Kalle, C Scholl, S Fröhling, B Brors, W Weichert, J Weitz, H Glimm
EMBO Mol Med, 2017;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Patient-Specific Screening Using High-Grade Glioma Explants to Determine Potential Radiosensitization by a TGF-? Small Molecule Inhibitor
Neoplasia, 2016;18(12):795-805.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
SOX2 and PI3K Cooperate to Induce and Stabilize a Squamous-Committed Stem Cell Injury State during Lung Squamous Cell Carcinoma Pathogenesis
PLoS Biol., 2016;14(11):e1002581.
Species: Human
Sample Types: Whole Cells
Applications: IHC-P -
RBPJ maintains brain tumor-initiating cells through CDK9-mediated transcriptional elongation
Authors: Qi Xie
J Clin Invest, 2016;126(7):2757-2772.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
An essential role of SVZ progenitors in cortical folding in gyrencephalic mammals
Sci Rep, 2016;6(0):29578.
Species: Ferret
Sample Types: Whole Tissue
Applications: IHC -
Traumatic Brain Injury Stimulates Neural Stem Cell Proliferation via Mammalian Target of Rapamycin Signaling Pathway Activation
Authors: Jinhui Chen
eNeuro, 2016;3(5):.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Mitochondrial control by DRP1 in brain tumor initiating cells.
Authors: Xie Q, Wu Q, Horbinski C, Flavahan W, Yang K, Zhou W, Dombrowski S, Huang Z, Fang X, Shi Y, Ferguson A, Kashatus D, Bao S, Rich J
Nat Neurosci, 2015;18(4):501-10.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
The chromatin regulator Brpf1 regulates embryo development and cell proliferation.
Authors: You L, Yan K, Zou J, Zhao H, Bertos N, Park M, Wang E, Yang X
J Biol Chem, 2015;290(18):11349-64.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
DNMT-dependent suppression of microRNA regulates the induction of GBM tumor-propagating phenotype by Oct4 and Sox2.
Authors: Lopez-Bertoni H, Lal B, Li A, Caplan M, Guerrero-Cazares H, Eberhart C, Quinones-Hinojosa A, Glas M, Scheffler B, Laterra J, Li Y
Oncogene, 2015;34(30):3994-4004.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Angiogenesis in the developing spinal cord: blood vessel exclusion from neural progenitor region is mediated by VEGF and its antagonists.
Authors: Takahashi, Teruaki, Takase, Yuta, Yoshino, Takashi, Saito, Daisuke, Tadokoro, Ryosuke, Takahashi, Yoshiko
PLoS ONE, 2015;10(1):e0116119.
Species: Avian - Quail
Sample Types: Whole Tissue
Applications: IHC-Fr -
Acellular lung scaffolds direct differentiation of endoderm to functional airway epithelial cells: requirement of matrix-bound HS proteoglycans.
Authors: Shojaie S, Ermini L, Ackerley C, Wang J, Chin S, Yeganeh B, Bilodeau M, Sambi M, Rogers I, Rossant J, Bear C, Post M
Stem Cell Reports, 2015;4(3):419-30.
Species: Mouse
Sample Types: Whole Cells
Applications: IHC -
Increased cycling cell numbers and stem cell associated proteins as potential biomarkers for high grade human papillomavirus+ve pre-neoplastic cervical disease.
Authors: Canham, Maurice, Charsou, Chara, Stewart, June, Moncur, Sharon, Hoodless, Laura, Bhatia, Ramya, Cong, Duanduan, Cubie, Heather, Busby-Earle, Camille, Williams, Alistair, McLoughlin, Victoria, Campbell, John D M, Cuschieri, Kate, Howie, Sarah
PLoS ONE, 2015;9(12):e115379.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
Deficiency of the chromatin regulator BRPF1 causes abnormal brain development.
Authors: You L, Zou J, Zhao H, Bertos N, Park M, Wang E, Yang X
J Biol Chem, 2015;290(11):7114-29.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
3D imaging of Sox2 enhancer clusters in embryonic stem cells.
Authors: Liu, Zhe, Legant, Wesley R, Chen, Bi-Chang, Li, Li, Grimm, Jonathan, Lavis, Luke D, Betzig, Eric, Tjian, Robert
Elife, 2014;3(0):e04236.
Species: Mouse
Sample Types: Cell Lysates
Applications: ChIP -
Positive feedback loop between Sox2 and Sox6 inhibits neuronal differentiation in the developing central nervous system.
Authors: Lee, Kyung Eu, Seo, Jihae, Shin, Jiheon, Ji, Eun Hye, Roh, Jiwon, Kim, Joo Yeon, Sun, Woong, Muhr, Jonas, Lee, Sanghyuk, Kim, Jaesang
Proc Natl Acad Sci U S A, 2014;111(7):2794-9.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Expression and regulation of prostate apoptosis response-4 (Par-4) in human glioma stem cells in drug-induced apoptosis.
Authors: Jagtap, Jayashre, Dawood, Parveen, Shah, Reecha D, Chandrika, Goparaju, Natesh, Kumar, Shiras, Anjali, Hegde, Amba S, Ranade, Deepak, Shastry, Padma
PLoS ONE, 2014;9(2):e88505.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
MOF-associated complexes ensure stem cell identity and Xist repression.
Authors: Chelmicki T, Dundar F, Turley M, Khanam T, Aktas T, Ramirez F, Gendrel A, Wright P, Videm P, Backofen R, Heard E, Manke T, Akhtar A
Elife, 2014;3(0):e02024.
Species: Mouse
Sample Types: Cell Lysates
Applications: ChIP -
Selective lentiviral gene delivery to CD133-expressing human glioblastoma stem cells.
Authors: Bayin, N Sumru, Modrek, Aram S, Dietrich, August, Lebowitz, Jonathan, Abel, Tobias, Song, Hae-Ri, Schober, Markus, Zagzag, David, Buchholz, Christia, Chao, Moses V, Placantonakis, Dimitris
PLoS ONE, 2014;9(12):e116114.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Lineage-specific splicing of a brain-enriched alternative exon promotes glioblastoma progression.
Authors: Ferrarese R, Harsh G, Yadav A, Bug E, Maticzka D, Reichardt W, Dombrowski S, Miller T, Masilamani A, Dai F, Kim H, Hadler M, Scholtens D, Yu I, Beck J, Srinivasasainagendra V, Costa F, Baxan N, Pfeifer D, von Elverfeldt D, Backofen R, Weyerbrock A, Duarte C, He X, Prinz M, Chandler J, Vogel H, Chakravarti A, Rich J, Carro M, Bredel M
J Clin Invest, 2014;124(7):2861-76.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
In vitro generation of neuromesodermal progenitors reveals distinct roles for wnt signalling in the specification of spinal cord and paraxial mesoderm identity.
Authors: Gouti, Mina, Tsakiridis, Anestis, Wymeersch, Filip J, Huang, Yali, Kleinjung, Jens, Wilson, Valerie, Briscoe, James
PLoS Biol, 2014;12(8):e1001937.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
GATA6 levels modulate primitive endoderm cell fate choice and timing in the mouse blastocyst.
Authors: Schrode N, Saiz N, Di Talia S, Hadjantonakis A
Dev Cell, 2014;29(4):454-67.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Neuronal activity promotes oligodendrogenesis and adaptive myelination in the mammalian brain.
Authors: Gibson, Erin M, Purger, David, Mount, Christop, Goldstein, Andrea K, Lin, Grant L, Wood, Lauren S, Inema, Ingrid, Miller, Sarah E, Bieri, Gregor, Zuchero, J Bradle, Barres, Ben A, Woo, Pamelyn, Vogel, Hannes, Monje, Michelle
Science, 2014;344(6183):1252304.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Role of SOX2 in the etiology of embryonal carcinoma, based on analysis of the NCCIT and NT2 cell lines.
Authors: Eini, Ronak, Stoop, Hans, Gillis, Ad J M, Biermann, Katharin, Dorssers, Lambert, Looijenga, Leendert
PLoS ONE, 2014;9(1):e83585.
Species: Human
Sample Types: Whole Cells
Applications: IHC-P -
Otx2 cell-autonomously determines dorsal mesencephalon versus cerebellum fate independently of isthmic organizing activity.
Authors: Di Giovannantonio, Luca G, Di Salvio, Michela, Omodei, Daniela, Prakash, Nilima, Wurst, Wolfgang, Pierani, Alessand, Acampora, Dario, Simeone, Antonio
Development, 2014;141(2):377-88.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Pharmacological inhibition of poly(ADP-ribose) polymerase-1 modulates resistance of human glioblastoma stem cells to temozolomide.
Authors: Tentori, Lucio, Ricci-Vitiani, Lucia, Muzi, Alessia, Ciccarone, Fabio, Pelacchi, Federica, Calabrese, Roberta, Runci, Daniele, Pallini, Roberto, Caiafa, Paola, Graziani, Grazia
BMC Cancer, 2014;14(0):151.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Efficient generation of human iPSCs by a synthetic self-replicative RNA.
Authors: Yoshioka N, Gros E, Li H, Kumar S, Deacon D, Maron C, Muotri A, Chi N, Fu X, Yu B, Dowdy S
Cell Stem Cell, 2013;13(2):246-54.
Species: Human
Sample Types: Whole Cells
Applications: IHC -
BEND6 is a nuclear antagonist of Notch signaling during self-renewal of neural stem cells.
Authors: Dai Q, Andreu-Agullo C, Insolera R, Wong L, Shi S, Lai E
Development, 2013;140(9):1892-902.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Transcription factors FOXG1 and Groucho/TLE promote glioblastoma growth.
Authors: Verginelli F, Perin A, Dali R, Fung K, Lo R, Longatti P, Guiot M, Del Maestro R, Rossi S, di Porzio U, Stechishin O, Weiss S, Stifani S
Nat Commun, 2013;4(0):2956.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
SOX2 expression associates with stem cell state in human ovarian carcinoma.
Authors: Bareiss, Petra M, Paczulla, Anna, Wang, Hui, Schairer, Rebekka, Wiehr, Stefan, Kohlhofer, Ursula, Rothfuss, Oliver C, Fischer, Anna, Perner, Sven, Staebler, Annette, Wallwiener, Diethelm, Fend, Falko, Fehm, Tanja, Pichler, Bernd, Kanz, Lothar, Quintanilla-Martinez, Leticia, Schulze-Osthoff, Klaus, Essmann, Frank, Lengerke, Claudia
Cancer Res, 2013;73(17):5544-55.
Species: Human
Sample Types: Whole Tissue
Applications: IHC -
Sox2 marks epithelial competence to generate teeth in mammals and reptiles.
Authors: Juuri, Emma, Jussila, Maria, Seidel, Kerstin, Holmes, Scott, Wu, Ping, Richman, Joy, Heikinheimo, Kristiin, Chuong, Cheng-Mi, Arnold, Katrin, Hochedlinger, Konrad, Klein, Ophir, Michon, Frederic, Thesleff, Irma
Development, 2013;140(7):1424-32.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-P -
Sex determining region Y-box 2 (SOX2) amplification is an independent indicator of disease recurrence in sinonasal cancer.
Authors: Schrock A, Goke F, Wagner P, Bode M, Franzen A, Braun M, Huss S, Agaimy A, Ihrler S, Menon R, Kirsten R, Kristiansen G, Bootz F, Lengerke C, Perner S
PLoS ONE, 2013;8(3):e59201.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
Genome-wide chromatin interactions of the Nanog locus in pluripotency, differentiation, and reprogramming.
Authors: Apostolou E, Ferrari F, Walsh R, Bar-Nur O, Stadtfeld M, Cheloufi S, Stuart H, Polo J, Ohsumi T, Borowsky M, Kharchenko P, Park P, Hochedlinger K
Cell Stem Cell, 2013;12(6):699-712.
Species: Mouse
Sample Types: Cell Lysates
Applications: ChIP -
The germinal matrices in the developing dentate gyrus are composed of neuronal progenitors at distinct differentiation stages.
Authors: Sugiyama T, Osumi N, Katsuyama Y
Dev Dyn, 2013;242(12):1442-53.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC -
Sox2 cooperates with Chd7 to regulate genes that are mutated in human syndromes.
Authors: Engelen E, Akinci U, Bryne JC
Nat. Genet., 2011;43(6):607-11.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Specific detection of OCT3/4 isoform A/B/B1 expression in solid (germ cell) tumours and cell lines: confirmation of OCT3/4 specificity for germ cell tumours.
Authors: Rijlaarsdam MA, van Herk HA, Gillis AJ
Br. J. Cancer, 2011;105(6):854-63.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P -
Sonic hedgehog signaling is decoded by calcium spike activity in the developing spinal cord.
Authors: Belgacem YH, Borodinsky LN,
Proc. Natl. Acad. Sci. U.S.A., 2011;108(11):4482-7.
Species: Xenopus
Sample Types: Whole Tissue
Applications: IHC -
A defined glycosaminoglycan-binding substratum for human pluripotent stem cells.
Authors: Klim JR, Li L, Wrighton PJ
Nat. Methods, 2010;7(12):989-94.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Activity-dependent expression of Lmx1b regulates specification of serotonergic neurons modulating swimming behavior.
Authors: Demarque M, Spitzer NC
Neuron, 2010;67(2):321-34.
Species: Xenopus
Sample Types: Whole Tissue
Applications: IHC-Fr -
SIP1 mediates cell-fate decisions between neuroectoderm and mesendoderm in human pluripotent stem cells.
Authors: Chng Z, Teo A, Pedersen RA, Vallier L
Cell Stem Cell, 2010;6(1):59-70.
Species: Human
Sample Types: Cell Lysates
Applications: ChIP -
Glioma stem cell lines expanded in adherent culture have tumor-specific phenotypes and are suitable for chemical and genetic screens.
Authors: Pollard SM, Yoshikawa K, Clarke ID, Danovi D, Stricker S, Russell R, Bayani J, Head R, Lee M, Bernstein M, Squire JA, Smith A, Dirks P
Cell Stem Cell, 2009;4(6):568-80.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Regulation of self-renewal and pluripotency by Sox2 in human embryonic stem cells.
Authors: Fong H, Hohenstein KA, Donovan PJ
Stem Cells, 2008;26(8):1931-8.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Epigenetic-mediated dysfunction of the bone morphogenetic protein pathway inhibits differentiation of glioblastoma-initiating cells.
Authors: Lee J, Son MJ, Woolard K, Donin NM, Li A, Cheng CH, Kotliarova S, Kotliarov Y, Walling J, Ahn S, Kim M, Totonchy M, Cusack T, Ene C, Ma H, Su Q, Zenklusen JC, Zhang W, Maric D, Fine HA
Cancer Cell, 2008;13(1):69-80.
Species: Human
Sample Types: Whole Cells
Applications: ICC -
Hyaluronan-CD44 interaction activates stem cell marker Nanog, Stat-3-mediated MDR1 gene expression, and ankyrin-regulated multidrug efflux in breast and ovarian tumor cells.
Authors: Bourguignon LY, Peyrollier K, Xia W, Gilad E
J. Biol. Chem., 2008;283(25):17635-51.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot -
Characterization of progenitor domains in the developing mouse thalamus.
Authors: Vue TY, Aaker J, Taniguchi A
J. Comp. Neurol., 2007;505(1):73-91.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC-Fr -
New cell lines from mouse epiblast share defining features with human embryonic stem cells.
Authors: Tesar PJ, Chenoweth JG, Brook FA, Davies TJ, Evans EP, Mack DL, Gardner RL, McKay RD
Nature, 2007;448(7150):196-9.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC -
Microglia instruct subventricular zone neurogenesis.
Authors: Walton NM, Sutter BM, Laywell ED, Levkoff LH, Kearns SM, Marshall GP, Scheffler B, Steindler DA
Glia, 2006;54(8):815-25.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC
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Reviews for Human/Mouse/Rat SOX2 Antibody
Average Rating: 3.5 (Based on 6 Reviews)
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Goat antibody used with Donkey anti goad linked to A647.
We have another SOX2 antibody that works beautiful in the same conditions but it's not goat (we wanted a goat one). But the secondary antibody works with other goat antibodies too.
staining of cortical spheroids derived from iPS cells
The sample (mouse embryonic lung) was fixed in 4% PFA for 1 hour and washed 3 times with PBS prior to embedding in OCT and cryosection. No antigen retrieval required. It labels the epithelial cells of bronchioles. Works Great!