Human TNF-alpha Quantikine HS ELISA

  (81 citations)   
Product Details
Citations (81)
FAQs
Supplemental Products
Reviews
  • Assay Length
    4 hours
  • Sample Type & Volume Required Per Well
    Serum (50 uL), EDTA Plasma (50 uL), Heparin Plasma (50 uL)
  • Sensitivity
    0.049 pg/mL
  • Assay Range
    0.2 - 10 pg/mL (Serum, EDTA Plasma, Heparin Plasma)
  • Specificity
    Natural and recombinant human TNF-alpha
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    No significant interference observed with available related molecules.
Control Available
QC232 , Quantikine Control Set 929 for Human HS TNF-a, HSTA00E - Please Inquire
Product Summary
The Quantikine HS Human TNF-alpha Immunoassay is a 6.5 hour solid phase ELISA designed to measure TNF-alpha in serum and plasma. It contains E. coli-derived recombinant human TNF-alpha and antibodies raised against the recombinant factor. It has been shown to accurately quantitate recombinant human TNF-alpha. Results obtained with naturally occurring TNF-alpha samples showed linear curves that were parallel to the standard curves obtained using the recombinant kit standards. These results indicate that this kit can be used to determine relative mass values for natural TNF-alpha. Since the measurement of TNF-alpha is insensitive to the addition of recombinant forms of either of the two types of soluble receptors, it is probable that this measurement detects the total amount of TNF-alpha in samples, i.e., the total amount of free TNF-alpha plus the amount of TNF-alpha bound to soluble receptors.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision.
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision.
Serum, EDTA Plasma, Heparin Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 20 20 20
Mean 1.07 3.3 6.71 1.09 3.26 6.51
Standard Deviation 0.024 0.066 0.129 0.073 0.22 0.406
CV% 2.2 2 1.9 6.7 6.7 6.2

Serum, EDTA Plasma, Heparin Plasma, Citrate Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 41 41 41
Mean 1.96 11.5 22.1 1.83 10.5 20.3
Standard Deviation 0.17 0.49 0.68 0.19 0.76 1.5
CV% 8.7 4.3 3.1 10.4 7.2 7.4

Recovery

The recovery of TNF-alpha was determined by spiking to three different levels throughout the range of the assay in various matrices.

Sample Type Average % Recovery Range %
EDTA Plasma (n=4) 97 80-111
Heparin Plasma (n=4) 96 80-111
Serum (n=4) 94 83-103
Linearity
To assess the linearity of the assay, samples were spiked with high concentrations of TNF-alpha and diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Human TNF-alpha Quantikine HS ELISA
Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: TNF-alpha

Tumor necrosis factor alpha (TNF-α), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, apoptosis, and immune system development. TNF-α is produced by a wide variety of immune and epithelial cell types. Human TNF-α consists of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD). Within the ECD, human TNF-α shares 97% aa sequence identity with rhesus and 71% - 92% with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-α. The 26 kDa type 2 transmembrane protein is assembled intracellularly to form a noncovalently linked homotrimer. Ligation of this complex induces reverse signaling that promotes lymphocyte costimulation but diminishes monocyte responsiveness.

Cleavage of membrane bound TNF-α by TACE/ADAM17 releases a 55 kDa soluble trimeric form of TNF-α. TNF-α trimers bind the ubiquitous TNF RI and the hematopoietic cell-restricted TNF RII, both of which are also expressed as homotrimers. TNF-α regulates lymphoid tissue development through control of apoptosis. It also promotes inflammatory responses by inducing the activation of vascular endothelial cells and macrophages. TNF-α is a key cytokine in the development of several inflammatory disorders. It contributes to the development of type 2 diabetes through its effects on insulin resistance and fatty acid metabolism.

  • Long Name:
    Tumor Necrosis Factor alpha
  • Entrez Gene IDs:
    7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
  • Alternate Names:
    APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; tnfa; tnf-a; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

81 Citations: Showing 1 - 10
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Species
Sample Type
  1. Repeated Excessive Exercise Attenuates the Anti-Inflammatory Effects of Exercise in Older Men
    Authors: RE Sahl, PR Andersen, K Gronbaek, TH Morville, M Rosenkilde, HK Rasmusen, SS Poulsen, C Prats, F Dela, JW Helge
    Front Physiol, 2017;8(0):407.
    Species: Human
    Sample Type: Plasma
  2. Association of plasma CD40L with acute chest syndrome in sickle cell anemia
    Authors: VT Garrido, L Sonzogni, SN Mtatiro, FF Costa, N Conran, SL Thein
    Cytokine, 2017;97(0):104-107.
    Species: Human
    Sample Type: Plasma
  3. Chemokine signals are crucial for enhanced homing and differentiation of circulating osteoclast progenitor cells
    Authors: A Sucur, Z Jajic, M Artukovic, MI Matijasevi, B Anic, D Flegar, A Markotic, T Kelava, S Ivcevic, N Kovacic, V Katavic, D Grcevic
    Arthritis Res. Ther., 2017;19(1):142.
    Species: Human
    Sample Type: Plasma
  4. Microenvironment inflammatory infiltrate drives growth speed and outcome of hepatocellular carcinoma: a prospective clinical study
    Authors: R Critelli, F Milosa, F Faillaci, R Condello, E Turola, L Marzi, B Lei, F Dituri, S Andreani, P Sighinolfi, P Manni, A Maiorana, C Caporali, F di Benedet, M Del Buono, N De Maria, F Schepis, ML Martinez-C, G Giannelli, E Villa
    Cell Death Dis, 2017;8(8):e3017.
    Species: Human
    Sample Type: Serum
  5. Visceral fat area is a strong predictor of leukocyte cell-derived chemotaxin 2, a potential biomarker of dyslipidemia
    Authors: K Tanisawa, H Taniguchi, X Sun, T Ito, R Kawakami, S Sakamoto, M Higuchi
    PLoS ONE, 2017;12(3):e0173310.
    Species: Human
    Sample Type: Serum
  6. Effects of nateglinide and rosiglitazone on pancreatic alpha- and beta-cells, GLP-1 secretion and inflammatory markers in patients with type 2 diabetes: randomized crossover clinical study.
    Authors: Tostes G, Cunha M, Fukui R, Correia M, Rocha D, Dos Santos R, da Silva M
    Diabetol Metab Syndr, 2016;8(0):1.
    Species: Human
    Sample Type: Serum
  7. The relationship between circulating neutrophil gelatinase-associated lipocalin and early alteration of metabolic parameters is associated with dietary saturated fat intake in non-diabetic Korean women
    Authors: GY Na, SR Yoon, J An, R Yeo, J Song, MN Jo, S Han, OY Kim
    Endocr. J, 2016;0(0):.
    Species: Human
    Sample Type: Plasma
  8. Anti-TNF-? Drugs Differently Affect the TNF?-sTNFR System and Monocyte Subsets in Patients with Psoriasis
    PLoS ONE, 2016;11(12):e0167757.
  9. Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury
    J Clin Invest, 2016;0(0):.
    Species: Human
    Sample Type: Serum
  10. Casein glycomacropeptide for active distal ulcerative colitis: a randomised pilot study
    Authors: CL Hvas, A Dige, M Bendix, PG Wernlund, LA Christense, JF Dahlerup, J Agnholt
    Eur J Clin Invest, 2016;0(0):.
    Species: Human
    Sample Type: Plasma
  11. Trait Hostility and Acute Inflammatory Responses to Stress in the Laboratory
    Authors: Dominique Girard
    PLoS ONE, 2016;11(6):e0156329.
    Species: Human
    Sample Type: Serum
  12. Reduction of c-Fos via Overexpression of miR-34a Results in Enhancement of TNF- Production by LPS in Neutrophils from Myelodysplastic Syndrome Patients
    PLoS ONE, 2016;11(8):e0158527.
    Species: Human
    Sample Type: Cell Culture Supernates
  13. Circadian misalignment increases cardiovascular disease risk factors in humans
    Proc. Natl. Acad. Sci. U.S.A., 2016;113(10):E1402-11.
    Species: Human
    Sample Type: Serum
  14. Interleukin-6 Is a Risk Factor for Atrial Fibrillation in Chronic Kidney Disease: Findings from the CRIC Study.
    Authors: Amdur R, Mukherjee M, Go A, Barrows I, Ramezani A, Shoji J, Reilly M, Gnanaraj J, Deo R, Roas S, Keane M, Master S, Teal V, Soliman E, Yang P, Feldman H, Kusek J, Tracy C, Raj D
    PLoS ONE, 2016;11(2):e0148189.
    Species: Human
    Sample Type: Plasma
  15. Plasma TNF-alpha and Soluble TNF Receptor Levels after Doxorubicin with or without Co-Administration of Mesna-A Randomized, Cross-Over Clinical Study.
    Authors: Hayslip J, Dressler E, Weiss H, Taylor T, Chambers M, Noel T, Miriyala S, Keeney J, Ren X, Sultana R, Vore M, Butterfield D, St Clair D, Moscow J
    PLoS ONE, 2015;10(4):e0124988.
    Species: Human
    Sample Type: Plasma
  16. A randomized, placebo controlled trial of omega-3 fatty acids in the treatment of young children with autism.
    Authors: Mankad D, Dupuis A, Smile S, Roberts W, Brian J, Lui T, Genore L, Zaghloul D, Iaboni A, Marcon P, Anagnostou E
    Mol Autism, 2015;6(0):18.
    Species: Human
    Sample Type: Plasma
  17. Effects of Acute Endurance Exercise Performed in the Morning and Evening on Inflammatory Cytokine and Metabolic Hormone Responses.
    Authors: Kim H, Konishi M, Takahashi M, Tabata H, Endo N, Numao S, Lee S, Kim Y, Suzuki K, Sakamoto S
    PLoS ONE, 2015;10(9):e0137567.
    Species: Human
    Sample Type: Plasma
  18. Sclerostin, TNF-alpha and Interleukin-18 Correlate and are Together with Klotho Related to Other Growth Factors and Cytokines in Haemodialysis Patients.
    Authors: Almroth G, Lonn J, Uhlin F, Brudin L, Andersson B, Hahn-Zoric M
    Scand J Immunol, 2015;83(1):58-63.
    Species: Human
    Sample Type: Serum
  19. Tumor-specific cytotoxic T lymphocyte activity determines colorectal cancer patient prognosis.
    Authors: Reissfelder C, Stamova S, Gossmann C, Braun M, Bonertz A, Walliczek U, Grimm M, Rahbari N, Koch M, Saadati M, Benner A, Buchler M, Jager D, Halama N, Khazaie K, Weitz J, Beckhove P
    J Clin Invest, 2015;125(2):739-51.
    Species: Human
    Sample Type: Tissue Homogenates
  20. Differential Patterns and Determinants of Cardiac Autonomic Nerve Dysfunction during Endotoxemia and Oral Fat Load in Humans.
    Authors: Ziegler D, Strom A, Strassburger K, Nowotny B, Zahiragic L, Nowotny P, Carstensen-Kirberg M, Herder C, Szendroedi J, Roden M
    PLoS ONE, 2015;10(4):e0124242.
    Species: Human
    Sample Type: Serum
  21. Effects of pentoxifylline on proteinuria and glucose control in patients with type 2 diabetes: a prospective randomized double-blind multicenter study.
    Authors: Han S, Kim H, Kim D, Sheen S, Chung C, Ahn C, Kim S, Cho Y, Park S, Kim S, Kim C, Kim K, Lee K
    Diabetol Metab Syndr, 2015;7(0):64.
    Species: Human
    Sample Type: Serum
  22. Association of Sarcopenic Obesity with Higher Serum High-Sensitivity C-Reactive Protein Levels in Chinese Older Males--A Community-Based Study (Taichung Community Health Study-Elderly, TCHS-E).
    Authors: Yang C, Li C, Li T, Liu C, Lin C, Lin W, Lin C
    PLoS ONE, 2015;10(7):e0132908.
    Species: Human
    Sample Type: Serum
  23. Disturbances in Hypothalamic-Pituitary-Adrenal Axis and Immunological Activity Differentiating between Unipolar and Bipolar Depressive Episodes.
    Authors: Becking K, Spijker A, Hoencamp E, Penninx B, Schoevers R, Boschloo L
    PLoS ONE, 2015;10(7):e0133898.
    Species: Human
    Sample Type: Plasma
  24. Association between Inflammation and Cardiac Geometry in Chronic Kidney Disease: Findings from the CRIC Study.
    Authors: Gupta J, Dominic E, Fink J, Ojo A, Barrows I, Reilly M, Townsend R, Joffe M, Rosas S, Wolman M, Patel S, Keane M, Feldman H, Kusek J, Raj D
    PLoS ONE, 2015;10(4):e0124772.
    Species: Human
    Sample Type: Plasma
  25. Tumor necrosis factor-alpha confers cardioprotection through ectopic expression of keratins K8 and K18.
    Authors: Papathanasiou S, Rickelt S, Soriano M, Schips T, Maier H, Davos C, Varela A, Kaklamanis L, Mann D, Capetanaki Y
    Nat Med, 2015;21(9):1076-84.
    Species: Human
    Sample Type: Serum
  26. Compartment differences of inflammatory activity in chronic obstructive pulmonary disease.
    Authors: Ji J, von Scheele I, Bergstrom J, Billing B, Dahlen B, Lantz A, Larsson K, Palmberg L
    Respir Res, 2014;15(0):104.
    Species: Human
    Sample Type: Serum
  27. Zinc supplementation improves anticancer activity of monocytes in type-2 diabetic patients with metabolic syndrome.
    Authors: Meksawan K, Sermsri U, Chanvorachote P
    Anticancer Res, 2014;34(1):295-9.
    Species: Human
    Sample Type: Plasma
  28. The protective effect of esculentoside a on experimental acute liver injury in mice.
    Authors: Zhang F, Wang X, Qiu X, Wang J, Fang H, Wang Z, Sun Y, Xia Z
    PLoS ONE, 2014;9(11):e113107.
    Species: Human
    Sample Type: Cell Culture Supernates
  29. Threonyl-tRNA synthetase overexpression correlates with angiogenic markers and progression of human ovarian cancer.
    Authors: Wellman T, Eckenstein M, Wong C, Rincon M, Ashikaga T, Mount S, Francklyn C, Lounsbury K
    BMC Cancer, 2014;14(0):620.
    Species: Human
    Sample Type: Serum
  30. Role of diacylglycerol activation of PKCtheta in lipid-induced muscle insulin resistance in humans.
    Authors: Szendroedi J, Yoshimura T, Phielix E, Koliaki C, Marcucci M, Zhang D, Jelenik T, Muller J, Herder C, Nowotny P, Shulman G, Roden M
    Proc Natl Acad Sci U S A, 2014;111(26):9597-602.
    Species: Human
    Sample Type: Plasma
  31. Circulating mitochondrial DNA increases with age and is a familiar trait: Implications for "inflamm-aging"
    Authors: Pinti M, Cevenini E, Nasi M, De Biasi S, Salvioli S, Monti D, Benatti S, Gibellini L, Cotichini R, Stazi M, Trenti T, Franceschi C, Cossarizza A
    Eur J Immunol, 2014;44(5):1552-62.
    Species: Human
    Sample Type: Plasma
  32. The impact of two different transfusion strategies on patient immune response during major abdominal surgery: a preliminary report.
    Authors: Theodoraki K, Markatou M, Rizos D, Fassoulaki A
    J Immunol Res, 2014;2014(0):945829.
    Species: Human
    Sample Type: Plasma
  33. High-salt intake induced visceral adipose tissue hypoxia and its association with circulating monocyte subsets in humans.
    Authors: Zhou X, Yuan F, Ji W, Guo Z, Zhang L, Lu R, Liu X, Liu H, Zhang W, Jiang T, Zhang Z, Li Y
    Obesity (Silver Spring), 2014;22(6):1470-6.
    Species: Human
    Sample Type: Serum
  34. Smac mimetics and innate immune stimuli synergize to promote tumor death.
    Authors: Beug S, Tang V, Lacasse E, Cheung H, Beauregard C, Brun J, Nuyens J, Earl N, St-Jean M, Holbrook J, Dastidar H, Mahoney D, Ilkow C, Le Boeuf F, Bell J, Korneluk R
    Nat Biotechnol, 2014;32(2):182-90.
    Species: Human
    Sample Type: Cell Culture Supernates
  35. Race modifies the association between adiposity and inflammation in patients with chronic kidney disease: findings from the chronic renal insufficiency cohort study.
    Authors: Wing M, Yang W, Teal V, Navaneethan S, Tao K, Ojo A, Guzman N, Reilly M, Wolman M, Rosas S, Cuevas M, Fischer M, Lustigova E, Master S, Xie D, Appleby D, Joffe M, Kusek J, Feldman H, Raj D
    Obesity (Silver Spring), 2014;22(5):1359-66.
    Species: Human
    Sample Type: Plasma
  36. Big breakfast rich in protein and fat improves glycemic control in type 2 diabetics.
    Authors: Rabinovitz H, Boaz M, Ganz T, Jakubowicz D, Matas Z, Madar Z, Wainstein J
    Obesity (Silver Spring), 2014;22(5):E46-54.
    Species: Human
    Sample Type: Plasma
  37. Association between traffic-related air pollution, subclinical inflammation and impaired glucose metabolism: results from the SALIA study.
    Authors: Teichert T, Vossoughi M, Vierkotter A, Sugiri D, Schikowski T, Schulte T, Roden M, Luckhaus C, Herder C, Kramer U
    PLoS ONE, 2013;8(12):e83042.
    Species: Human
    Sample Type: Plasma
  38. Engulfment of hematopoietic stem cells caused by down-regulation of CD47 is critical in the pathogenesis of hemophagocytic lymphohistiocytosis.
    Authors: Kuriyama T, Takenaka K, Kohno K, Yamauchi T, Daitoku S, Yoshimoto G, Kikushige Y, Kishimoto J, Abe Y, Harada N, Miyamoto T, Iwasaki H, Teshima T, Akashi K
    Blood, 2012;120(19):4058-67.
    Species: Human
    Sample Type: Serum
  39. Multiplexing immunoassays for cytokine detection in the serum of patients with rheumatoid arthritis: lack of sensitivity and interference by rheumatoid factor.
    Authors: Churchman SM, Geiler J, Parmar R, Horner EA, Church LD, Emery P, Buch MH, McDermott MF, Ponchel F
    Clin. Exp. Rheumatol., 2012;30(4):534-42.
    Species: Human
    Sample Type: Serum
  40. A randomized trial of recombinant human granulocyte-macrophage colony stimulating factor for patients with acute lung injury.
    Authors: Paine R, Standiford TJ, Dechert RE, Moss M, Martin GS, Rosenberg AL, Thannickal VJ, Burnham EL, Brown MB, Hyzy RC
    Crit. Care Med., 2012;40(1):90-7.
    Species: Human
    Sample Type: BALF
  41. Fractalkine is an independent predictor of mortality in patients with advanced heart failure.
    Thromb Haemost, 2012;108(6):1220-7.
    Species: Human
    Sample Type: Plasma
  42. Adipocytokine levels mark endothelial function in normotensive individuals.
    Authors: Solini A, Stea F, Santini E, Bruno R, Duranti E, Taddei S, Ghiadoni L
    Cardiovasc Diabetol, 2012;11(0):103.
    Species: Human
    Sample Type: Plasma
  43. Mechanisms inducing low bone density in duchenne muscular dystrophy in mice and humans.
    Authors: Rufo A, Del Fattore A, Capulli M, Carvello F, De Pasquale L, Ferrari S, Pierroz D, Morandi L, De Simone M, Rucci N, Bertini E, Bianchi ML, De Benedetti F, Teti A
    J. Bone Miner. Res., 2011;26(8):1891-903.
    Species: Human
    Sample Type: Serum
  44. Effects of dietary fat modification on insulin sensitivity and on other risk factors of the metabolic syndrome-LIPGENE: a European randomized dietary intervention study.
    Authors: Tierney AC, McMonagle J, Shaw DI, Gulseth HL, Helal O, Saris WH, Paniagua JA, Golabek-Leszczynska I, Defoort C, Williams CM, Karsltrom B, Vessby B, Dembinska-Kiec A, Lopez-Miranda J, Blaak EE, Drevon CA, Gibney MJ, Lovegrove JA, Roche HM
    Int J Obes (Lond), 2011;35(6):800-9.
    Species: Human
    Sample Type: Serum
  45. Time-course of changes in inflammatory response after whole-body cryotherapy multi exposures following severe exercise.
    Authors: Pournot H, Bieuzen F, Louis J, Fillard JR, Barbiche E, Hausswirth C
    PLoS ONE, 2011;6(7):e22748.
    Species: Human
    Sample Type: Plasma
  46. Differential adaptation of human gut microbiota to bariatric surgery-induced weight loss: links with metabolic and low-grade inflammation markers.
    Authors: Furet JP, Kong LC, Tap J, Poitou C, Basdevant A, Bouillot JL, Mariat D, Corthier G, Dore J, Henegar C, Rizkalla S, Clement K
    Diabetes, 2010;59(12):3049-57.
    Species: Human
    Sample Type: Plasma
  47. Nonalcoholic fatty liver disease as the transducer of hepatic oversecretion of very-low-density lipoprotein-apolipoprotein B-100 in obesity.
    Authors: Chan DC, Watts GF, Gan S
    Arterioscler. Thromb. Vasc. Biol., 2010;30(5):1043-50.
    Species: Human
    Sample Type: Plasma
  48. Changes in cytokine levels during acute hyperinsulinemia in offspring of type 2 diabetic subjects.
    Authors: Ruotsalainen E, Stancakova A, Vauhkonen I, Salmenniemi U, Pihlajamaki J, Punnonen K, Laakso M
    Atherosclerosis, 2010;210(2):536-41.
    Species: Human
    Sample Type: Plasma
  49. B7-h3 augments the inflammatory response and is associated with human sepsis.
    Authors: Zhang G, Wang J, Kelly J
    J. Immunol., 2010;185(6):3677-84.
    Species: Human
    Sample Type: Plasma
  50. Sensitive plasma protein analysis by microparticle-based proximity ligation assays.
    Authors: Darmanis S, Nong RY, Hammond M, Gu J, Alderborn A, Vanelid J, Siegbahn A, Gustafsdottir S, Ericsson O, Landegren U, Kamali-Moghaddam M
    Mol. Cell Proteomics, 2010;9(2):327-35.
    Species: Human
    Sample Type: Plasma
  51. SIRT1 mRNA expression may be associated with energy expenditure and insulin sensitivity.
    Authors: Rutanen J, Yaluri N, Modi S, Pihlajamaki J, Vanttinen M, Itkonen P, Kainulainen S, Yamamoto H, Lagouge M, Sinclair DA, Elliott P, Westphal C, Auwerx J, Laakso M
    Diabetes, 2010;59(4):829-35.
    Species: Human
    Sample Type: Plasma
  52. Prehospital resuscitation with hypertonic saline-dextran modulates inflammatory, coagulation and endothelial activation marker profiles in severe traumatic brain injured patients.
    Authors: Rhind SG, Crnko NT, Baker AJ
    J Neuroinflammation, 2010;7(0):5.
    Species: Human
    Sample Type: Serum
  53. Procalcitonin as an early marker of bacterial infection in neutropenic febrile children with acute lymphoblastic leukemia.
    Authors: Hatzistilianou M, Rekliti A, Athanassiadou F, Catriu D
    Inflamm. Res., 2010;59(5):339-47.
    Species: Human
    Sample Type: Serum
  54. Sex differences in inflammatory markers: what is the contribution of visceral adiposity?
    Authors: Cartier A, Cote M, Lemieux I, Perusse L, Tremblay A, Bouchard C, Despres JP
    Am. J. Clin. Nutr., 2009;89(5):1307-14.
    Species: Human
    Sample Type: Plasma
  55. Serum CXCL13 positively correlates with prostatic disease, prostate-specific antigen and mediates prostate cancer cell invasion, integrin clustering and cell adhesion.
    Authors: Singh S, Singh R, Sharma PK, Singh UP, Rai SN, Chung LW, Cooper CR, Novakovic KR, Grizzle WE, Lillard JW
    Cancer Lett., 2009;283(1):29-35.
    Species: Human
    Sample Type: Serum
  56. Resistin, adiponectin, and risk of heart failure the Framingham offspring study.
    Authors: Frankel DS, Vasan RS, D'Agostino RB, Benjamin EJ, Levy D, Wang TJ, Meigs JB
    J. Am. Coll. Cardiol., 2009;53(9):754-62.
    Species: Human
    Sample Type: Plasma
  57. Intervention of an inflammation amplifier, triggering receptor expressed on myeloid cells 1, for treatment of autoimmune arthritis.
    Authors: Murakami Y, Akahoshi T, Aoki N, Toyomoto M, Miyasaka N, Kohsaka H
    Arthritis Rheum., 2009;60(6):1615-23.
    Species: Human
    Sample Type: Serum
  58. Adiposity and gingival crevicular fluid tumour necrosis factor-alpha levels in children.
    Authors: Khosravi R, Tran SD, Lambert M, O'Loughlin J, Kâ K, Feine JS, Caron C, Tremblay A, Nicolau B
    J. Clin. Periodontol., 2009;36(4):301-7.
    Species: Human
    Sample Type: Gingival Crevicular Fluid (GCF)
  59. Characteristics of dengue virus-infected peripheral blood mononuclear cell death that correlates with the severity of illness.
    Authors: Jaiyen Y, Masrinoul P, Kalayanarooj S, Pulmanausahakul R, Ubol S
    Microbiol. Immunol., 2009;53(8):442-50.
    Species: Human
    Sample Type: Plasma
  60. Interleukin-6 is a significant predictor of radiographic knee osteoarthritis: The Chingford Study.
    Authors: Livshits G, Zhai G, Hart DJ, Kato BS, Wang H, Williams FM, Spector TD
    Arthritis Rheum., 2009;60(7):2037-45.
    Species: Human
    Sample Type: Serum
  61. Age-dependent mobilization of circulating endothelial progenitor cells in infants and young children undergoing cardiac surgery with cardiopulmonary bypass.
    Authors: Sun Y, Yi D, Wang Y, Zheng R, Sun G, Wang J, Liu Y, Ren J, Wang Y, Zhang S, Gu C, Pei J
    Cytokine, 2009;47(3):206-13.
    Species: Human
    Sample Type: Plasma
  62. Acetaldehyde stimulates monocyte adhesion in a P-selectin- and TNFalpha-dependent manner.
    Authors: Redmond EM, Morrow D, Kundimi S, Miller-Graziano CL, Cullen JP
    Atherosclerosis, 2009;204(2):372-80.
    Species: Human
    Sample Type: Cell Culture Supernates
  63. Interleukin-18 is a strong predictor of cardiovascular events in elderly men with the metabolic syndrome: synergistic effect of inflammation and hyperglycemia.
    Authors: Troseid M, Seljeflot I, Hjerkinn EM, Arnesen H
    Diabetes Care, 2009;32(3):486-92.
    Species: Human
    Sample Type: Serum
  64. Urinary proinflammatory cytokine response in renal transplant recipients with polyomavirus BK viruria.
    Authors: Sadeghi M, Daniel V, Schnitzler P, Lahdou I, Naujokat C, Zeier M, Opelz G
    Transplantation, 2009;88(9):1109-16.
    Species: Human
    Sample Type: Urine
  65. Smoking, inflammatory patterns and postprandial hypertriglyceridemia.
    Authors: Kabagambe EK, Ordovas JM, Tsai MY, Borecki IB, Hopkins PN, Glasser SP, Arnett DK
    Atherosclerosis, 2009;203(2):633-9.
    Species: Human
    Sample Type: Serum
  66. The proinflammatory environment in potential heart and lung donors: prevalence and impact of donor management and hormonal therapy.
    Authors: Venkateswaran RV, Dronavalli V, Lambert PA, Steeds RP, Wilson IC, Thompson RD, Mascaro JG, Bonser RS
    Transplantation, 2009;88(4):582-8.
    Species: Human
    Sample Type: Serum
  67. Immunomodulation by chronobiologically-based glucocorticoids treatment for multiple sclerosis relapses.
    Authors: Glass-Marmor L, Paperna T, Galboiz Y, Miller A
    J. Neuroimmunol., 2009;210(1):124-7.
    Species: Human
    Sample Type: Serum
  68. Duffy antigen modifies the chemokine response in human endotoxemia.
    Authors: Mayr FB, Spiel AO, Leitner JM, Firbas C, Kliegel T, Jilma-Stohlawetz P, Derendorf H, Jilma B
    Crit. Care Med., 2008;36(1):159-65.
    Species: Human
    Sample Type: Plasma
  69. Low-dose acetylsalicylic acid inhibits the secretion of interleukin-6 from white adipose tissue.
    Authors: Ogston NC, Karastergiou K, Hosseinzadeh-Attar MJ, Bhome R, Madani R, Stables M, Gilroy D, Flachs P, Hensler M, Kopecky J, Mohamed-Ali V
    Int J Obes (Lond), 2008;32(12):1807-15.
    Species: Human
    Sample Type: Plasma
  70. Comparing Type D personality and older age as correlates of tumor necrosis factor-alpha dysregulation in chronic heart failure.
    Authors: Denollet J, Vrints CJ, Conraads VM
    Brain Behav. Immun., 2008;22(5):736-43.
    Species: Human
    Sample Type: Plasma
  71. Neutropenia in 6 ethnic groups from the Caribbean and the U.S.
    Authors: Grann VR, Bowman N, Joseph C, Wei Y, Horwitz MS, Jacobson JS, Santella RP, Hershman DL
    Cancer, 2008;113(4):854-60.
    Species: Human
    Sample Type: Plasma
  72. Duffy (Fy), DARC, and neutropenia among women from the United States, Europe and the Caribbean.
    Authors: Grann VR, Ziv E, Joseph CK, Neugut AI, Wei Y, Jacobson JS, Horwitz MS, Bowman N, Beckmann K, Hershman DL
    Br. J. Haematol., 2008;143(2):288-93.
    Species: Human
    Sample Type: Plasma
  73. Effects of atorvastatin added to inhaled corticosteroids on lung function and sputum cell counts in atopic asthma.
    Authors: Hothersall EJ, Chaudhuri R, McSharry C, Donnelly I, Lafferty J, McMahon AD, Weir CJ, Meiklejohn J, Sattar N, McInnes I, Wood S, Thomson NC
    Thorax, 2008;63(12):1070-5.
    Species: Human
    Sample Type: Serum
  74. Self-esteem levels and cardiovascular and inflammatory responses to acute stress.
    Authors: O'Donnell K, Brydon L, Wright CE, Steptoe A
    Brain Behav. Immun., 2008;0(0):.
    Species: Human
    Sample Type: Plasma
  75. In vivo transmigrated monocytes from patients with stable coronary artery disease have a reduced expression of CD11b.
    Authors: Paulsson JM, Dadfar E, Held C, Jacobson SH, Lundahl J
    Clin. Exp. Immunol., 2008;153(2):196-204.
    Species: Human
    Sample Type: Serum
  76. Identification of interleukin-7 as a candidate disease mediator in spondylarthritis.
    Authors: Rihl M, Kellner H, Kellner W, Barthel C, Yu DT, Tak PP, Zeidler H, Baeten D
    Arthritis Rheum., 2008;58(11):3430-5.
    Species: Human
    Sample Type: Synovial Fluid
  77. Effects of rehabilitative exercise on peripheral muscle TNFalpha, IL-6, IGF-I and MyoD expression in patients with COPD.
    Authors: Vogiatzis I, Stratakos G, Simoes DC, Terzis G, Georgiadou O, Roussos C, Zakynthinos S
    Thorax, 2007;62(11):950-6.
    Species: Human
    Sample Type: Plasma
  78. Co-occurrence of IgA antibodies against ethanol metabolites and tissue transglutaminase in alcohol consumers: correlation with proinflammatory cytokines and markers of fibrogenesis.
    Authors: Koivisto H, Hietala J, Anttila P, Niemela O
    Dig. Dis. Sci., 2007;53(2):500-5.
    Species: Human
    Sample Type: Serum
  79. The activity of N-acetyl-beta-D-glucosaminidase and tumor necrosis factor-alpha at early stage of diabetic retinopathy development in type 1 diabetes mellitus children.
    Authors: Mysliwiec M, Zorena K, Balcerska A, Mysliwska J, Lipowski P, Raczynska K
    Clin. Biochem., 2006;39(8):851-6.
    Species: Human
    Sample Type: Serum
  80. Cerebrospinal fluid IL-6, HSP72, and TNF-alpha in exercising humans.
    Authors: Steensberg A, Dalsgaard MK, Secher NH, Pedersen BK
    Brain Behav. Immun., 2006;20(6):585-9.
    Species: Human
    Sample Type: Plasma
  81. Postprandial total and HMW adiponectin following a high-fat meal in lean, obese and diabetic men.
    Authors: Phillips L, Peake J, Zhang X, Hickman I, Briskey D, Huang B, Simpson P, Li S, Whitehead J, Martin J, Prins J
    Eur J Clin Nutr, 0;67(4):377-84.
    Species: Human
    Sample Type: Plasma
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Quantikine Control Set 929 for Human HS TNF-a, HSTA00E

QC232
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