Rat IL-6 Quantikine ELISA Kit

  (64 citations)     
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Product Details
Citations (64)
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  • Assay Length
    4.5 hours
  • Specificity
    Natural and recombinant rat IL-6
  • Cross-reactivity
    < 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
  • Interference
    No significant interference observed with available related molecules.
Product Summary
The Quantikine Rat IL-6 Immunoassay is a 4.5 hour solid phase ELISA designed to measure rat IL-6 in cell culture supernates, rat serum, and plasma. It contains E. coli-expressed recombinant rat IL-6 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant protein. Results obtained using natural rat IL-6 showed dose-response curves that were parallel to the standard curves obtained using the Quantikine kit standards. These results indicate that this kit can be used to determine relative mass values for natural rat IL-6.

Precision
Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision
Cell Culture Supernates, Serum, EDTA Plasma
Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 22 27 28
Mean 120 256 1028 134 268 987
Standard Deviation 10.6 22.4 46.2 13.4 21.7 69.2
CV% 8.8 8.8 4.5 10 8.1 7

Recovery

The recovery of rat IL-6 spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=5) 103 85-118
EDTA Plasma (n=5) 96 81-111
Serum (n=5) 97 91-105
Linearity
To assess the linearity of the assay, five or more samples containing and/or spiked with various concentrations of rat IL-6 in each matrix were diluted with Calibrator Diluent and then assayed.
 IL-6 [HRP]
Product Datasheets

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Preparation and Storage
  • Storage
    Store the unopened product at 2 - 8 °C. Do not use past expiration date.
Background: IL-6
IL-6 (Interleukin-6) is a pleiotropic cytokine that acts in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. It contributes to chronic inflammation in obesity, insulin resistance, inflammatory bowel disease, arthritis, sepsis, and atherosclerosis. IL-6 signals through a receptor complex of IL-6 R alpha and gp130. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 R alpha are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 R alpha elicit responses from gp130-expressing cells that lack cell surface IL-6 R alpha.
  • Long Name:
    Interleukin 6
  • Entrez Gene IDs:
    3569 (Human); 16193 (Mouse); 24498 (Rat); 399500 (Porcine); 280826 (Bovine); 403985 (Canine); 100034196 (Equine); 493687 (Feline); 100008733 (Rabbit)
  • Alternate Names:
    B cell stimulatory factor-2; B-cell differentiation factor; BSF-2; BSF2CTL differentiation factor; CDF; HGFHSFIFNB2Hybridoma growth factor; IFN-beta-2; IL6; IL-6; IL-6B-cell stimulatory factor 2; Interferon beta-2; interleukin 6 (interferon, beta 2); interleukin BSF-2; interleukin-6; MGI-2A
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

64 Citations: Showing 1 - 10
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Species
Sample Type
  1. Narrow Spectrum Kinase Inhibitors Demonstrate Promise for the Treatment of Dry Eye Disease and Other Ocular Inflammatory Disorders
    Authors: S Hagan, MCT Fyfe, B Ofori-Frim, K Oliver, MR Foster, S Sirohi, Y Solanke, M Doughty, A Rowley, M Taylor, S Webber, CA Walshe
    Invest. Ophthalmol. Vis. Sci., 2018;59(3):1443-1453.
    Species: Rat
    Sample Type: Tissue Homogenates
  2. Ablation of the Right Cardiac Vagus Nerve Reduces Acetylcholine Content without Changing the Inflammatory Response during Endotoxemia
    Authors: K Plaschke, TQM Do, F Uhle, T Brenner, MA Weigand, J Kopitz
    Int J Mol Sci, 2018;19(2):.
    Species: Rat
    Sample Type: Plasma
  3. The Effects of Remifentanil on Expression of High Mobility Group Box 1 in Septic Rats
    Authors: KH Seo, JW Choi, HS Jung, H Yoo, JD Joo
    J. Korean Med. Sci, 2017;32(3):542-551.
    Species: Rat
    Sample Type: Serum
  4. Anti-aging effect and gene expression profiling of dung beetle glycosaminoglycan in aged rats
    Authors: MY Ahn, BJ Kim, HJ Kim, JS Hwang, YS Jung, KK Park
    Biomater Res, 2017;21(0):5.
    Species: Rat
    Sample Type: Serum
  5. Short-term treatment with taurolidine is associated with liver injury
    Authors: R Fahrner, A Möller, AT Press, A Kortgen, M Kiehntopf, F Rauchfuss, U Settmacher, AS Mosig
    BMC Pharmacol Toxicol, 2017;18(1):61.
    Species: Rat
    Sample Type: Serum
  6. Maternal-placental-fetal biodistribution of multimodal polymeric nanoparticles in a pregnant rat model in mid and late gestation
    Authors: D Ho, JW Leong, RC Crew, M Norret, MJ House, PJ Mark, BJ Waddell, KS Iyer, JA Keelan
    Sci Rep, 2017;7(1):2866.
    Species: Rat
    Sample Type: Plasma
  7. Protective effects of GV1001 on myocardial ischemia?reperfusion injury
    Authors: JE Chang, HJ Kim, S Jheon, C Lim
    Mol Med Rep, 2017;0(0):.
    Species: Rat
    Sample Type: Tissue Homogenates
  8. Mori Folium water extract alleviates articular cartilage damages and inflammatory responses in monosodium iodoacetate?induced osteoarthritis rats
    Authors: JW Jeong, HH Lee, J Kim, EO Choi, H Hwang-Bo, HJ Kim, MY Kim, KI Ahn, GY Kim, KW Lee, KY Kim, SG Kim, SH Hong, C Park, HJ Cha, YH Choi
    Mol Med Rep, 2017;0(0):.
    Species: Rat
    Sample Type: Serum
  9. Topical use and systemic action of green and roasted coffee oils and ground oils in a cutaneous incision model in rats (Rattus norvegicus albinus)
    Authors: BG Lania, J Morari, AL Souza, MND Silva, AR de Almeida, G Veira-Dami, SM Alegre, CL César, LA Velloso, ML Cintra, NB Maia, PENF Velho
    PLoS ONE, 2017;12(12):e0188779.
    Species: Rat
    Sample Type: Serum
  10. Aliskiren has chondroprotective efficacy in a rat model of osteoarthritis through suppression of the local renin-angiotensin system
    Authors: K Yan, Y Shen
    Mol Med Rep, 2017;0(0):.
    Species: Rat
    Sample Type: Serum
  11. Intraneural injection of ATP stimulates regeneration of primary sensory axons in the spinal cord
    Authors: D Wu, S Lee, J Luo, H Xia, S Gushchina, PM Richardson, J Yeh, U Krügel, H Franke, Y Zhang, X Bo
    J. Neurosci., 2017;0(0):.
    Species: Rat
    Sample Type: Tissue Homogenates
  12. Investigation of the effect of phlomisoside F on complete Freund's adjuvant-induced arthritis
    Authors: X Zhang, Y Dong, H Dong, W Zhang, F Li
    Exp Ther Med, 2017;13(2):710-716.
    Species: Rat
    Sample Type: Serum
  13. The P2X7 receptor links mechanical strain to cytokine IL-6 upregulation and release in neurons and astrocytes
    Authors: W Lu, F Albalawi, JM Beckel, JC Lim, AM Laties, CH Mitchell
    J. Neurochem, 2017;0(0):.
    Species: Rat
    Sample Type: Cell Lysates
  14. Negligible Oval Cell Proliferation Following Ischemia-Reperfusion Injury With and Without Partial Hepatectomy
    Authors: EK Tan, M Shuh, H Francois-V, JA Sanders, AJ Cohen
    Ochsner J, 2017;17(1):31-37.
    Species: Rat
    Sample Type: Serum
  15. The analgesic effect of rolipram is associated with the inhibition of the activation of the spinal astrocytic JNK/CCL2 pathway in bone cancer pain
    Authors: Chi-Hua Guo
    Int. J. Mol. Med, 2016;38(5):1433-1442.
    Species: Rat
    Sample Type: Tissue Homogenates
  16. IL-17A is implicated in lipopolysaccharide-induced neuroinflammation and cognitive impairment in aged rats via microglial activation.
    Authors: Sun J, Zhang S, Zhang X, Zhang X, Dong H, Qian Y
    J Neuroinflammation, 2015;12(0):165.
  17. Effect of Silodosin, an Alpha1A-Adrenoceptor Antagonist, on Ventral Prostatic Hyperplasia in the Spontaneously Hypertensive Rat.
    Authors: Shimizu S, Shimizu T, Tsounapi P, Higashi Y, Martin D, Nakamura K, Honda M, Inoue K, Saito M
    PLoS ONE, 2015;10(8):e0133798.
  18. Melatonin attenuates the TLR4-mediated inflammatory response through MyD88- and TRIF-dependent signaling pathways in an in vivo model of ovarian cancer.
    Authors: Chuffa L, Fioruci-Fontanelli B, Mendes L, Ferreira Seiva F, Martinez M, Favaro W, Domeniconi R, Pinheiro P, Delazari Dos Santos L, Martinez F
    BMC Cancer, 2015;15(0):34.
    Species: Rat
    Sample Type: Tissue Culture Supernates
  19. Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy.
    Authors: Ahmed M, Kumar G, Navarro G, Wang Y, Gourevitch S, Moussa M, Rozenblum N, Levchenko T, Galun E, Torchilin V, Goldberg S
    PLoS ONE, 2015;10(7):e0128910.
    Species: Rat
    Sample Type: Serum
  20. Iron-hepcidin dysmetabolism, anemia and renal hypoxia, inflammation and fibrosis in the remnant kidney rat model.
    Authors: Garrido P, Ribeiro S, Fernandes J, Vala H, Bronze-da-Rocha E, Rocha-Pereira P, Belo L, Costa E, Santos-Silva A, Reis F
    PLoS ONE, 2015;10(4):e0124048.
    Species: Rat
    Sample Type: Serum
  21. The extent of irradiation-induced long-term visceral organ damage depends on cranial/brain exposure.
    Authors: Boittin F, Denis J, Mayol J, Martigne P, Raffin F, Coulon D, Grenier N, Drouet M, Herodin F
    PLoS ONE, 2015;10(4):e0122900.
    Species: Rat
    Sample Type: Plasma
  22. Perioperative aspirin improves neurological outcome after focal brain ischemia possibly via inhibition of Notch 1 in rat.
    Authors: Wang Z, Huang W, Zuo Z
    J Neuroinflammation, 2014;11(0):56.
    Species: Rat
    Sample Type: Whole Tissue
  23. Microglia trigger astrocyte-mediated neuroprotection via purinergic gliotransmission.
    Authors: Shinozaki Y, Nomura M, Iwatsuki K, Moriyama Y, Gachet C, Koizumi S
    Sci Rep, 2014;4(0):4329.
    Species: Rat
    Sample Type: Cell Culture Supernates
  24. Electrical stimulation induces IL-6 in skeletal muscle through extracellular ATP by activating Ca(2+) signals and an IL-6 autocrine loop.
    Authors: Bustamante M, Fernandez-Verdejo R, Jaimovich E, Buvinic S
    Am J Physiol Endocrinol Metab, 2014;306(8):E869-82.
    Species: Rat
    Sample Type: Cell Culture Supernates
  25. Quiescent hepatic stellate cells functionally contribute to the hepatic innate immune response via TLR3.
    Authors: Wilson C, Mann J, Walsh M, Perrugoria M, Oakley F, Wright M, Brignole C, Di Paolo D, Perri P, Ponzoni M, Karin M, Mann D
    PLoS ONE, 2014;9(1):e83391.
    Species: Rat
    Sample Type: Cell Culture Supernates
  26. Catalpol ameliorates sodium taurocholate-induced acute pancreatitis in rats via inhibiting activation of nuclear factor kappa B.
    Authors: Xiao W, Yin G, Fan Y, Qiu L, Cang X, Yu G, Hu Y, Xing M, Wu D, Wang X, Hu G, Wan R
    Int J Mol Sci, 2014;15(7):11957-72.
    Species: Rat
    Sample Type: Serum
  27. Targeting miR-21 inhibits in vitro and in vivo multiple myeloma cell growth.
    Authors: Leone E, Morelli E, Di Martino M, Amodio N, Foresta U, Gulla A, Rossi M, Neri A, Giordano A, Munshi N, Anderson K, Tagliaferri P, Tassone P
    Clin Cancer Res, 2013;19(8):2096-106.
    Species: Human
    Sample Type: Cell Culture Supernates
  28. Mechanical ventilation enhances HMGB1 expression in an LPS-induced lung injury model.
    Authors: Ding N, Wang F, Xiao H, Xu L, She S
    PLoS ONE, 2013;8(9):e74633.
    Species: Rat
    Sample Type: BALF
  29. A short course of infusion of a hydrogen sulfide-donor attenuates endotoxemia induced organ injury via stimulation of anti-inflammatory pathways, with no additional protection from prolonged infusion.
    Cytokine, 2013;61(2):614-21.
    Species: Rat
    Sample Type: BALF
  30. Early cardiac changes in a rat model of prediabetes: brain natriuretic peptide overexpression seems to be the best marker.
    Authors: Nunes S, Soares E, Fernandes J, Viana S, Carvalho E, Pereira F, Reis F
    Cardiovasc Diabetol, 2013;12(0):44.
    Species: Rat
    Sample Type: Serum
  31. Increased intrahepatic resistance in severe steatosis: endothelial dysfunction, vasoconstrictor overproduction and altered microvascular architecture.
    Authors: Francque S, Laleman W, Verbeke L, Van Steenkiste C, Casteleyn C, Kwanten W, Van Dyck C
    Lab Invest, 2012;92(10):1428-39.
    Species: Rat
    Sample Type: Serum
  32. Keratinocyte expression of inflammatory mediators plays a crucial role in substance P-induced acute and chronic pain.
    J Neuroinflammation, 2012;9(0):181.
    Species: Rat
    Sample Type: Tissue Homogenates
  33. Vipera aspis venom reduces lethality and down-regulates tumor necrosis factor-alpha in a rat model of LPS-induced sepsis.
    Authors: Frolkis I, Klein Y, Locker C, Adi N, Dahan E, Uretzsky G, Shapira I, Sorkine P
    Cytokine, 2010;49(3):319-24.
    Species: Rat
    Sample Type: Serum
  34. In vivo Angiotensin II AT1 receptor blockade selectively inhibits LPS-induced innate immune response and ACTH release in rat pituitary gland.
    Authors: Sanchez-Lemus E, Benicky J, Pavel J, Saavedra JM
    Brain Behav. Immun., 2009;23(7):945-57.
    Species: Rat
    Sample Type: Plasma
  35. Mechanism of hepatoprotection in proestrus female rats following trauma-hemorrhage: heme oxygenase-1-derived normalization of hepatic inflammatory responses.
    Authors: Yang S, Hu S, Chen J, Choudhry MA, Rue LW, Bland KI, Chaudry IH
    J. Leukoc. Biol., 2009;85(6):1015-26.
    Species: Rat
    Sample Type: Serum
  36. Hypercapnic acidosis attenuates shock and lung injury in early and prolonged systemic sepsis.
    Authors: Costello J, Higgins B, Contreras M, Chonghaile MN, Hassett P, O'Toole D, Laffey JG
    Crit. Care Med., 2009;37(8):2412-20.
    Species: Rat
    Sample Type: BALF
  37. Role of central beta-adrenergic receptors in regulating proinflammatory cytokine responses to a peripheral bacterial challenge.
    Authors: Johnson JD, Cortez V, Kennedy SL, Foley TE, Hanson H, Fleshner M
    Brain Behav. Immun., 2008;22(7):1078-86.
    Species: Rat
    Sample Type: Plasma
  38. Regulation of liver cytochrome P450 by activation of brain dopaminergic system: physiological and pharmacological implications.
    Authors: Wojcikowski J, Golembiowska K, Daniel WA
    Biochem. Pharmacol., 2008;76(2):258-67.
    Species: Rat
    Sample Type: Plasma
  39. Antithrombin inhibits bronchoalveolar activation of coagulation and limits lung injury during Streptococcus pneumoniae pneumonia in rats.
    Authors: Choi G, Hofstra JJ, Roelofs JJ, Rijneveld AW, Bresser P, van der Zee JS, Florquin S, van der Poll T, Levi M, Schultz MJ
    Crit. Care Med., 2008;36(1):204-10.
    Species: Rat
    Sample Type: BALF
  40. JAK/STAT3 pathway is activated in spinal cord microglia after peripheral nerve injury and contributes to neuropathic pain development in rat.
    Authors: Dominguez E, Rivat C, Pommier B, Mauborgne A, Pohl M
    J. Neurochem., 2008;107(1):50-60.
    Species: Rat
    Sample Type: Tissue Homogenates
  41. Trauma and hemorrhage-induced acute hepatic insulin resistance: dominant role of tumor necrosis factor-alpha.
    Authors: Xu J, Kim HT, Ma Y, Zhao L, Zhai L, Kokorina N, Wang P, Messina JL
    Endocrinology, 2008;149(5):2369-82.
    Species: Rat
    Sample Type: Serum
  42. Induction of type 2 iodothyronine deiodinase in the mediobasal hypothalamus by bacterial lipopolysaccharide: role of corticosterone.
    Authors: Sanchez E, Singru PS, Fekete C, Lechan RM
    Endocrinology, 2008;149(5):2484-93.
    Species: Rat
    Sample Type: Serum
  43. Comprehensive gene expression profiling of rat lung reveals distinct acute and chronic responses to cigarette smoke inhalation.
    Authors: Stevenson CS, Docx C, Webster R, Battram C, Hynx D, Giddings J, Cooper PR, Chakravarty P, Rahman I, Marwick JA, Kirkham PA, Charman C, Richardson DL, Nirmala NR, Whittaker P, Butler K
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(5):L1183-93.
    Species: Rat
    Sample Type: BALF
  44. Natural anticoagulants limit lipopolysaccharide-induced pulmonary coagulation but not inflammation.
    Authors: Choi G, Vlaar AP, Schouten M, Van't Veer C, van der Poll T, Levi M, Schultz MJ
    Eur. Respir. J., 2007;30(3):423-8.
    Species: Rat
    Sample Type: Tissue Homogenates
  45. ACE mediates ventilator-induced lung injury in rats via angiotensin II but not bradykinin.
    Authors: Wosten-van Asperen RM, Lutter R, Haitsma JJ, Merkus MP, van Woensel JB, van der Loos CM, Florquin S, Lachmann B, Bos AP
    Eur. Respir. J., 2007;31(2):363-71.
    Species: Rat
    Sample Type: BALF
  46. Changes of gene expression of iron regulatory proteins during turpentine oil-induced acute-phase response in the rat.
    Authors: Sheikh N, Dudas J, Ramadori G
    Lab. Invest., 2007;87(7):713-25.
    Species: Rat
    Sample Type: Serum
  47. Cell-based angiopoietin-1 gene therapy for acute lung injury.
    Authors: McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ
    Am. J. Respir. Crit. Care Med., 2007;175(10):1014-26.
    Species: Rat
    Sample Type: BALF
  48. Anti-rat soluble IL-6 receptor antibody down-regulates cardiac IL-6 and improves cardiac function following trauma-hemorrhage.
    Authors: Yang S, Hu S, Choudhry MA, Rue LW, Bland KI, Chaudry IH
    J. Mol. Cell. Cardiol., 2007;42(3):620-30.
    Species: Rat
    Sample Type: Plasma
  49. Mechanism of the nongenomic effects of estrogen on intestinal myeloperoxidase activity following trauma-hemorrhage: up-regulation of the PI-3K/Akt pathway.
    Authors: Yu HP, Hsieh YC, Suzuki T, Choudhry MA, Schwacha MG, Bland KI, Chaudry IH
    J. Leukoc. Biol., 2007;82(3):774-80.
    Species: Rat
    Sample Type: Tissue Homogenates
  50. The cytokine interleukin-6 is sufficient but not necessary to mimic the peripheral conditioning lesion effect on axonal growth.
    Authors: Cao Z, Gao Y, Bryson JB, Hou J, Chaudhry N, Siddiq M, Martinez J, Spencer T, Carmel J, Hart RB, Filbin MT
    J. Neurosci., 2006;26(20):5565-73.
    Species: Rat
    Sample Type: Cell Culture Supernates
  51. Effects of gabexate mesilate on serum inflammatory cytokines in rats with acute necrotizing pancreatitis.
    Authors: Chen CC, Wang SS, Tsay SH, Lee FY, Lu RH, Chang FY, Lee SD
    Cytokine, 2006;33(2):95-9.
    Species: Rat
    Sample Type: Serum
  52. Identification of astrocyte-expressed factors that modulate neural stem/progenitor cell differentiation.
    Authors: Barkho BZ, Song H, Aimone JB
    Stem Cells Dev., 2006;15(3):407-21.
    Species: Rat
    Sample Type: Cell Culture Supernates
  53. Suppression of ocular inflammation in endotoxin-induced uveitis by inhibiting nonproteolytic activation of prorenin.
    Authors: Satofuka S, Ichihara A, Nagai N, Yamashiro K, Koto T, Shinoda H, Noda K, Ozawa Y, Inoue M, Tsubota K, Suzuki F, Oike Y, Ishida S
    Invest. Ophthalmol. Vis. Sci., 2006;47(6):2686-92.
    Species: Rat
    Sample Type: Tissue Homogenates
  54. Biomarker and drug-target discovery using proteomics in a new rat model of sepsis-induced acute renal failure.
    Authors: Holly MK, Dear JW, Hu X, Schechter AN, Gladwin MT, Hewitt SM, Yuen PS, Star RA
    Kidney Int., 2006;70(3):496-506.
    Species: Rat
    Sample Type: Serum
  55. Glucosamine administration during resuscitation improves organ function after trauma hemorrhage.
    Authors: Yang S, Zou LY, Bounelis P, Chaudry I, Chatham JC, Marchase RB
    Shock, 2006;25(6):600-7.
    Species: Rat
    Sample Type: Plasma
  56. Developmental changes induced by graded prenatal systemic hypoxic-ischemic insults in rats.
    Authors: Robinson S, Petelenz K, Li Q, Cohen ML, Dechant A, Tabrizi N, Bucek M, Lust D, Miller RH
    Neurobiol. Dis., 2005;18(3):568-81.
    Species: Rat
    Sample Type: Amniotic Fluid
  57. Interleukin-10 aerosol reduces proinflammatory mediators in bronchoalveolar fluid of endotoxemic rat.
    Authors: Hofstetter C, Flondor M, Hoegl S, Muhl H, Zwissler B
    Crit. Care Med., 2005;33(10):2317-22.
    Species: Rat
    Sample Type: BALF
  58. Insulin attenuates the systemic inflammatory response in endotoxemic rats.
    Authors: Jeschke MG, Klein D, Bolder U, Einspanier R
    Endocrinology, 2004;145(9):4084-93.
    Species: Rat
    Sample Type: Tissue Homogenates
  59. Insulin treatment improves hepatic morphology and function through modulation of hepatic signals after severe trauma.
    Authors: Schubert T, Horch RE
    Ann. Surg., 2004;240(2):340-9.
    Species: Rat
    Sample Type: Tissue Homogenates
  60. Anti-inflammatory effects of alpha-melanocyte-stimulating hormone against rat endotoxin-induced uveitis and the time course of inflammatory agents in aqueous humor.
    Authors: Nishida T, Miyata S, Itoh Y, Mizuki N, Ohgami K, Shiratori K, Ilieva IB, Ohno S, Taylor AW
    Int. Immunopharmacol., 2004;4(8):1059-66.
    Species: Rat
    Sample Type: Aqueous humor
  61. A method for measuring multiple cytokines from small samples.
    Authors: O&amp;amp;apos;Connor KA
    Brain Behav. Immun., 2004;18(3):274-80.
    Species: Rat
    Sample Type: CSF
  62. HIV-1 gp120 stimulates proinflammatory cytokine-mediated pain facilitation via activation of nitric oxide synthase-I (nNOS).
    Authors: Holguin A, O&amp;amp;apos;Connor KA, Biedenkapp J, Campisi J, Wieseler-Frank J, Milligan ED, Hansen MK, Spataro L, Maksimova E, Bravmann C, Martin D, Fleshner M, Maier SF, Watkins LR
    Pain, 2004;110(3):517-30.
    Species: Rat
    Sample Type: CSF
  63. Differential expression of cytokine genes and inducible nitric oxide synthase induced by opacity phenotype variants of Streptococcus pneumoniae during acute otitis media in the rat.
    Authors: Long JP, Tong HH, Shannon PA, DeMaria TF
    Infect. Immun., 2003;71(10):5531-40.
    Species: Rat
    Sample Type: Tissue Secretion
  64. Iron intake increases infarct volume after permanent middle cerebral artery occlusion in rats.
    Authors: Castellanos M, Puig N, Carbonell T, Castillo J, Martinez J, Rama R, Davalos A
    Brain Res., 2002;952(1):1-6.
    Species: Rat
    Sample Type: Serum
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