Recombinant Human TNF-alpha Protein

Formulations:
Catalog # Availability Size / Price Qty
210-TA-020
210-TA-100
210-TA-005
Recombinant Human TNF-alpha Protein Bioactivity
2 Images
Product Details
Citations (525)
FAQs
Supplemental Products
Reviews (20)

Recombinant Human TNF-alpha Protein Summary

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 221. The ED50 for this effect is 25-100 pg/mL.
The specific activity of Recombinant Human TNF-alpha is approximately 7.6 x 104 IU/μg, which is calibrated against human TNF-alpha WHO International Standard (NIBSC code: 88/786).
Source
E. coli-derived human TNF-alpha protein
Val77-Leu233, with and without an N-terminal Met
Accession #
N-terminal Sequence
Analysis
Met & Val77
Predicted Molecular Mass
17.5 kDa
SDS-PAGE
17 kDa, reducing conditions

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

210-TA

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

210-TA/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity Recombinant Human TNF-alpha Protein Bioactivity View Larger

Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 25‑100 pg/mL.

SDS-PAGE Recombinant Human TNF-alpha Protein SDS-PAGE View Larger

1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: TNF-alpha

Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (1, 2). Human TNF-alpha consisits of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD) (3). Within the ECD, human TNF-alpha shares 97% aa sequence identity with rhesus and 71%-92% with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-alpha. TNF-alpha is produced by a wide variety of immune, epithelial, endothelial, and tumor cells (1, 2). TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface (4). Cell surface TNF-alpha can induce the lysis of neighboring tumor cells and virus infected cells, and it can generate its own downstream cell signaling following ligation by soluble TNFR I (2, 5). Shedding of membrane bound TNF-alpha by TACE/ADAM17 releases the bioactive cytokine, a 55 kDa soluble trimer of the TNF-alpha extracellular domain (6-8). TNF-alpha binds the ubiquitous 55-60 kDa TNF RI (9, 10) and the hematopoietic cell-restricted 80 kDa TNF RII (11, 12), both of which are also expressed as homotrimers (1, 2, 13). Both type I and type II receptors bind TNF-alpha with comparable affinity (14), although only TNF RI contains a cytoplasmic death domain which triggers the activation of apoptosis. Soluble forms of both types of receptors are released and can neutralize the biological activity of TNF-alpha (15).

References
  1. Zelova, H. and J. Hosek (2013) Inflamm. Res. 62:641.
  2. Juhasz, K. et al. (2013) Expert Rev. Clin. Immunol. 9:335.
  3. Pennica, D. et al. (1984) Nature 312:724.
  4. Tang, P. et al. (1996) Biochemistry 35:8216.
  5. Perez, C. et al. (1990) Cell 63:251.
  6. Black, R.A. et al. (1997) Nature 385:729.
  7. Moss, M.L. et al. (1997) Nature 385:733.
  8. Gearing, A.J.H. et al. (1994) Nature 370:555.
  9. Schall, T.J. et al. (1990) Cell 61:361.
  10. Loetscher, H. et al. (1990) Cell 61:351.
  11. Dembic, Z. et al. (1990) Cytokine 2:231.
  12. Smith, C.A. et al. (1990) Science 248:1019.
  13. Loetscher, H. et al. (1991) J. Biol. Chem. 266:18324.
  14. Pinckard, J.K. et al. (1997) J. Biol. Chem. 272:10784.
  15. Engelmann, H. et al. (1990) J. Biol. Chem. 265:1531.
Long Name
Tumor Necrosis Factor alpha
Entrez Gene IDs
7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
Alternate Names
APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; tnfa; tnf-a; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha

Citations for Recombinant Human TNF-alpha Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

525 Citations: Showing 1 - 10
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  1. Induction of innate immune memory via microRNA targeting of chromatin remodelling factors
    Authors: JJ Seeley, RG Baker, G Mohamed, T Bruns, MS Hayden, SD Deshmukh, DE Freedberg, S Ghosh
    Nature, 2018;559(7712):114-119.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Arsenite exposure potentiates apoptosis-inducing effects of tumor necrosis factor-alpha- through reactive oxygen species
    Authors: P Singhirunn, B Moolmuang, K Lirdprapam, M Ruchirawat
    J Toxicol Sci, 2018;43(2):159-169.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  3. A20 regulates canonical wnt-signaling through an interaction with RIPK4
    Authors: BN Nakamura, A Glazier, MG Kattah, B Duong, Y Jia, D Campo, L Shao
    PLoS ONE, 2018;13(5):e0195893.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  4. The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts
    Authors: M Armaka, C Ospelt, M Pasparakis, G Kollias
    Nat Commun, 2018;9(1):618.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. High-Mobility Group Box 1 in Dry Eye Inflammation
    Authors: C Lema, RY Reins, RL Redfern
    Invest. Ophthalmol. Vis. Sci., 2018;59(5):1741-1750.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Virus-like infection induces human ? cell dedifferentiation
    Authors: M Oshima, KP Knoch, M Diedisheim, A Petzold, P Cattan, M Bugliani, P Marchetti, P Choudhary, GC Huang, SR Bornstein, M Solimena, O Albagli-Cu, R Scharfmann
    JCI Insight, 2018;3(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms
    Authors: E Vorkapic, A Kunath, D Wågsäter
    Mol Med Rep, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  8. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
    Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
    Sci Rep, 2018;8(1):1561.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Lipoxin A4 Attenuates the Inflammatory Response in Stem Cells of the Apical Papilla via ALX/FPR2
    Authors: A Gaudin, M Tolar, OA Peters
    Sci Rep, 2018;8(1):8921.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models
    Authors: A Lundin, L Delsing, M Clausen, P Ricchiuto, J Sanchez, A Sabirsh, M Ding, J Synnergren, H Zetterberg, G Brolén, R Hicks, A Herland, A Falk
    Stem Cell Reports, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Interactome analysis of transforming growth factor-?-activated kinase 1 inHelicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37
    Authors: O Sokolova, T Kähne, K Bryan, M Naumann
    Oncotarget, 2018;9(18):14366-14381.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties
    Authors: M Gabl, M Sundqvist, A Holdfeldt, S Lind, J Mårtensson, K Christenso, T Marutani, C Dahlgren, H Mukai, H Forsman
    J. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  13. NF-?B inducing kinase is a therapeutic target for systemic lupus erythematosus
    Authors: HD Brightbill, E Suto, N Blaquiere, N Ramamoorth, S Sujatha-Bh, EB Gogol, GM Castanedo, BT Jackson, YC Kwon, S Haller, J Lesch, K Bents, C Everett, PB Kohli, S Linge, L Christian, K Barrett, A Jaochico, LM Berezhkovs, PW Fan, Z Modrusan, K Veliz, MJ Townsend, J DeVoss, AR Johnson, R Godemann, WP Lee, CD Austin, BS McKenzie, JA Hackney, JJ Crawford, ST Staben, MH Alaoui Ism, LC Wu, N Ghilardi
    Nat Commun, 2018;9(1):179.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  14. Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus
    Authors: D Sireesh, U Dhamodhara, K Ezhilarasi, V Vijay, KM Ramkumar
    Sci Rep, 2018;8(1):5126.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies
    Authors: R Jalili, J Horecka, JR Swartz, RW Davis, HHJ Persson
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Applications: Bioassay
  16. Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation
    Authors: JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani
    Cell Death Dis, 2018;9(6):665.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Voriconazole-induced photocarcinogenesis is promoted by aryl hydrocarbon receptor-dependent COX-2 upregulation
    Authors: S Ikeya, JI Sakabe, T Yamada, T Naito, Y Tokura
    Sci Rep, 2018;8(1):5050.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Angiokine Wisp-1 is increased in myocardial infarction and regulates cardiac endothelial signaling
    Authors: LH Wright, DJ Herr, SS Brown, H Kasiganesa, DR Menick
    JCI Insight, 2018;3(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Sulforaphane rescues amyloid-? peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages
    Authors: KA Jhang, JS Park, HS Kim, YH Chong
    J Neuroinflammation, 2018;15(1):75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  20. LRRC15 promotes osteogenic differentiation of mesenchymal stem cells by modulating p65 cytoplasmic/nuclear translocation
    Authors: Y Wang, Y Liu, M Zhang, L Lv, X Zhang, P Zhang, Y Zhou
    Stem Cell Res Ther, 2018;9(1):65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells
    Authors: X Zhang, Y Zhang, J Xu, H Wang, X Zheng, Y Lou, B Han
    J Cancer, 2018;9(2):367-374.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
    Authors: AE Dodi, IO Ajayi, C Chang, M Beard, SL Ashley, SK Huang, VJ Thannickal, DJ Tschumperl, TH Sisson, JC Horowitz
    Respir. Res., 2018;19(1):91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  23. mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy
    Authors: SU Seo, SM Woo, HS Lee, SH Kim, KJ Min, TK Kwon
    Oncogene, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  24. EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells
    Authors: YJ Choi, SJ Park, YS Park, HS Park, KM Yang, K Heo
    PLoS ONE, 2018;13(1):e0190638.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
    Authors: M Boyd, M Thodberg, M Vitezic, J Bornholdt, K Vitting-Se, Y Chen, M Coskun, Y Li, BZS Lo, P Klausen, P Jan Schwei, AG Pedersen, N Rapin, K Skovgaard, K Dahlgaard, R Andersson, TB Terkelsen, B Lilje, JT Troelsen, AM Petersen, KB Jensen, I Gögenur, P Thielsen, JB Seidelin, OH Nielsen, JT Bjerrum, A Sandelin
    Nat Commun, 2018;9(1):1661.
    Species: Human
    Sample Types: Organoids
    Applications: Bioassay
  26. Galectin-3 Plays an Important Role in Preterm Birth Caused by Dental Infection of Porphyromonas gingivalis
    Authors: M Miyauchi, M Ao, H Furusho, C Chea, A Nagasaki, S Sakamoto, T Ando, T Inubushi, K Kozai, T Takata
    Sci Rep, 2018;8(1):2867.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Hyaluronic Acid Influence on Normal and Osteoarthritic Tissue-Engineered Cartilage
    Authors: S Hemmati-Sa, J Ringe, T Dehne, R Haag, M Sittinger
    Int J Mol Sci, 2018;19(5):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  28. DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway
    Authors: F Zhang, G Liu, D Li, C Wei, J Hao
    J. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  29. The proximal tubular ?7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction
    Authors: H Kim, SR Kim, J Je, K Jeong, S Kim, HJ Kim, KC Chang, SW Park
    Exp. Mol. Med., 2018;50(4):40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. Restoration of E-cadherin by PPBICA protects against cisplatin-induced acute kidney injury by attenuating inflammation and programmed cell death
    Authors: L Gao, MM Liu, HM Zang, QY Ma, Q Yang, L Jiang, GL Ren, HD Li, WF Wu, JN Wang, B Wei, XQ Liu, C Jiang, C Huang, J Li, XM Meng
    Lab. Invest., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
    Authors: MA Rapsomanik, XK Lun, S Woerner, M Laumanns, B Bodenmille, MR Martínez
    Nat Commun, 2018;9(1):632.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  32. Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-?
    Authors: M Schwede, EM Wilfong, RL Zemans, PJ Lee, C Dos Santos, X Fang, MA Matthay
    Physiol Rep, 2018;6(16):e13831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Bridging pro-inflammatory signals, synaptic transmission and protection in spinal explants in vitro
    Authors: M Medelin, V Giacco, A Aldinucci, G Castronovo, E Bonechi, A Sibilla, M Tanturli, M Torcia, L Ballerini, F Cozzolino, C Ballerini
    Mol Brain, 2018;11(1):3.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  34. Nucleoside Diphosphate Kinase-3 (NME3) Enhances TLR5-Induced NF-?B Activation
    Authors: K Flentie, C Gonzalez, B Kocher, Y Wang, H Zhu, J Marasa, D Piwnica-Wo
    Mol. Cancer Res., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. C/EBP? drives interactions between human MAIT cells and endothelial cells that are important for extravasation
    Authors: CH Lee, HH Zhang, SP Singh, L Koo, J Kabat, H Tsang, TP Singh, JM Farber
    Elife, 2018;7(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients
    Authors: E Canto, N Isobe, A Didonna,, SL Hauser, JR Oksenberg
    J Neuroinflammation, 2018;15(1):72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer
    Authors: AL Means, TJ Freeman, J Zhu, LG Woodbury, P Marincola-, C Wu, AR Meyer, CJ Weaver, C Padmanabha, H An, J Zi, BC Wessinger, R Chaturvedi, TD Brown, NG Deane, RJ Coffey, KT Wilson, JJ Smith, CL Sawyers, JR Goldenring, SV Novitskiy, MK Washington, C Shi, RD Beauchamp
    Cell Mol Gastroenterol Hepatol, 2018;6(3):257-276.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress
    Authors: V Tisato, S Gallo, E Melloni, C Celeghini, A Passaro, G Zauli, P Secchiero, C Bergamini, A Trentini, G Bonaccorsi, G Valacchi, G Zuliani, C Cervellati
    Mediators Inflamm., 2018;2018(0):9629537.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Sodium Butyrate Attenuates Diarrhea in Weaned Piglets and Promotes Tight Junction Protein Expression in Colon in a GPR109A-Dependent Manner
    Authors: W Feng, Y Wu, G Chen, S Fu, B Li, B Huang, D Wang, W Wang, J Liu
    Cell. Physiol. Biochem., 2018;47(4):1617-1629.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion
    Authors: S Ishii, T Isozaki, H Furuya, H Takeuchi, Y Tsubokura, K Inagaki, T Kasama
    Arthritis Res. Ther., 2018;20(1):159.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes
    Authors: SL Figenschau, E Knutsen, I Urbarova, C Fenton, B Elston, M Perander, ES Mortensen, KA Fenton
    Sci Rep, 2018;8(1):11720.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Proton irradiation orchestrates macrophage reprogramming through NF?B signaling
    Authors: G Genard, AC Wera, C Huart, B Le Calve, S Penninckx, A Fattacciol, T Tabarrant, C Demazy, N Ninane, AC Heuskin, S Lucas, C Michiels
    Cell Death Dis, 2018;9(7):728.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Elevated Expression of AXL May Contribute to the Epithelial-to-Mesenchymal Transition in Inflammatory Bowel Disease Patients
    Authors: É Boros, Z Kellermaye, P Balogh, G Strifler, A Vörös, P Sarlós, Á Vincze, C Varga, I Nagy
    Mediators Inflamm., 2018;2018(0):3241406.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  44. STAT3/NF-?B-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer
    Authors: WY Kuo, L Hwu, CY Wu, JS Lee, CW Chang, RS Liu
    Theranostics, 2017;7(3):647-663.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Identification of a small molecule that primes the type I interferon response to cytosolic DNA
    Authors: S Khiar, M Lucas-Hour, S Nisole, N Smith, O Helynck, M Bourgine, C Ruffié, JP Herbeuval, H Munier-Leh, F Tangy, PO Vidalain
    Sci Rep, 2017;7(1):2561.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Suppression of human arthritis synovial fibroblasts inflammation using dexamethasone-carbon nanotubes via increasing caveolin-dependent endocytosis and recovering mitochondrial membrane potential
    Authors: YK Lee, SW Kim, JY Park, WC Kang, YJ Kang, D Khang
    Int J Nanomedicine, 2017;12(0):5761-5779.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  47. AAV-based dual-reporter circuit for monitoring cell signaling in living human cells
    Authors: Z Zhang, Z Stickney, N Duong, K Curley, B Lu
    J Biol Eng, 2017;11(0):18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
    Authors: M Frank-Bert, M Trenkmann, K Klein, E Karouzakis, H Rehrauer, A Bratus, C Kolling, M Armaka, A Filer, BA Michel, RE Gay, CD Buckley, G Kollias, S Gay, C Ospelt
    Nat Commun, 2017;8(0):14852.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Association of HMGB1 with oxidative stress markers and regulators in PDR
    Authors: AM Abu El-Asr, K Alam, M Garcia-Ram, A Ahmad, MM Siddiquei, G Mohammad, A Mousa, G De Hertogh, G Opdenakker, R Simó
    Mol. Vis., 2017;23(0):853-871.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-?-Induced NF-?B Activation
    Authors: Z Wang, MY Li, C Mi, KS Wang, J Ma, X Jin
    Int J Mol Sci, 2017;18(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  51. ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
    Authors: JS Reyat, M Chimen, PJ Noy, J Szyroka, GE Rainger, MG Tomlinson
    J. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation
    Authors: KA Bailey, FG Haj, SI Simon, AG Passerini
    Sci Rep, 2017;7(1):8196.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis
    Authors: H Al Faruque, JH Kang, SR Hwang, S Sung, MM Alam, KH Sa, EJ Nam, YR Byun, YM Kang
    PLoS ONE, 2017;12(4):e0176110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Ziziphus nummularia Inhibits Inflammation-Induced Atherogenic Phenotype of Human Aortic Smooth Muscle Cells
    Authors: M Fardoun, T Al-Shehabi, A El-Yazbi, K Issa, F Zouein, D Maaliki, R Iratni, AH Eid
    Oxid Med Cell Longev, 2017;2017(0):4134093.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  55. A type of human skin dendritic cell marked by CD5 is associated with the development of inflammatory skin disease
    Authors: D Korenfeld, L Gorvel, A Munk, J Man, A Schaffer, T Tung, C Mann, E Klechevsky
    JCI Insight, 2017;2(18):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Proinflammatory Cytokines IL-6 and TNF-? Increased Telomerase Activity through NF-?B/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells
    Authors: SS Chung, Y Wu, Q Okobi, D Adekoya, M Atefi, O Clarke, P Dutta, JV Vadgama
    Mediators Inflamm., 2017;2017(0):5958429.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis
    Authors: BK Hong, S You, SA Yoo, D Park, D Hwang, CS Cho, WU Kim
    Exp. Mol. Med., 2017;49(8):e363.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Inhibition of 6-phosphofructo-2-kinase suppresses fibroblast-like synoviocytes- mediated synovial inflammation and joint destruction in rheumatoid arthritis
    Authors: Y Zou, S Zeng, M Huang, Q Qiu, Y Xiao, M Shi, Z Zhan, L Liang, X Yang, H Xu
    Br. J. Pharmacol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. CXorf48 is a potential therapeutic target for achieving treatment-free remission in CML patients
    Authors: M Matsushita, K Ozawa, T Suzuki, M Nakamura, N Nakano, S Kanchi, D Ichikawa, E Matsuki, M Sakurai, D Karigane, H Kasahara, N Tsukamoto, T Shimizu, T Mori, H Nakajima, S Okamoto, Y Kawakami, Y Hattori
    Blood Cancer J, 2017;7(9):e601.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Augmented Serum Amyloid A1/2 Mediated by TNF-induced NF-?B in Human Serous Ovarian Epithelial Tumors
    Authors: H Choi, RMC Ignacio, ES Lee, AJ Wilson, D Khabele, DS Son
    Immune Netw, 2017;17(2):121-127.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
    Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
    Autophagy, 2017;0(0):0.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Upregulation of circulating microRNA-134 in adult-onset Still's disease and its use as potential biomarker
    Authors: TL Liao, YM Chen, CW Hsieh, HH Chen, HC Lee, WT Hung, KT Tang, DY Chen
    Sci Rep, 2017;7(1):4214.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation
    Authors: S Ebtehaj, EG Gruppen, M Parvizi, UJF Tietge, RPF Dullaart
    Cardiovasc Diabetol, 2017;16(1):132.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Analytical ultracentrifugation with fluorescence detection system reveals differences in complex formation between recombinant human TNF and different biological TNF antagonists in various environments
    Authors: E Krayukhina, M Noda, K Ishii, T Maruno, H Wakabayash, M Tada, T Suzuki, A Ishii-Wata, M Kato, S Uchiyama
    MAbs, 2017;9(4):664-679.
    Applications: Bioassay
  65. Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy
    Authors: R Havunen, M Siurala, S Sorsa, S Grönberg-V, M Behr, S Tähtinen, JM Santos, P Karell, J Rusanen, DM Nettelbeck, A Ehrhardt, A Kanerva, A Hemminki
    Mol Ther Oncolytics, 2017;4(0):77-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. MicroRNA-155 induction via TNF-? and IFN-? suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells
    Authors: D Yee, KM Shah, MC Coles, TV Sharp, D Lagos
    J. Biol. Chem., 2017;292(50):20683-20693.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice
    Authors: GW He, C Günther, V Thonn, YQ Yu, E Martini, B Buchen, MF Neurath, M Stürzl, C Becker
    J. Exp. Med., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  68. Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching
    Authors: R Ahmad, B Rah, D Bastola, P Dhawan, AB Singh
    Sci Rep, 2017;7(1):5125.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor
    Authors: AT Holdbrooks, CM Britain, SL Bellis
    J. Biol. Chem., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Comprehensive proteome analysis of human skeletal muscle in cachexia and sarcopenia: A pilot study
    Authors: HA Ebhardt, S Degen, V Tadini, A Schilb, N Johns, CA Greig, KC Fearon, R Aebersold, C Jacobi
    J Cachexia Sarcopenia Muscle, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis
    Authors: E Couderc, F Morel, P Levillain, A Buffière-M, M Camus, C Paquier, C Bodet, JF Jégou, M Pohin, L Favot, M Garcia, V Huguier, J Mcheik, C Lacombe, H Yssel, G Guillet, FX Bernard, JC Lecron
    PLoS ONE, 2017;12(7):e0181486.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Substance P enhances proliferation and paracrine potential of adipose-derived stem cells in�vitro
    Authors: S Kim, J Piao, Y Son, HS Hong
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Long noncoding RNA NEAT1 promotes nasopharyngeal carcinoma progression through regulation of miR-124/NF-?B pathway
    Authors: N Cheng, Y Guo
    Onco Targets Ther, 2017;10(0):5843-5853.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  74. An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors
    Authors: CH Lo, N Vunnam, AK Lewis, TL Chiu, BE Brummel, TM Schaaf, BD Grant, P Bawaskar, DD Thomas, JN Sachs
    SLAS Discov, 2017;0(0):2472555217706.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Healing of Preterm Ruptured Fetal Membranes
    Authors: H Mogami, A Hari Kisho, Y Akgul, RA Word
    Sci Rep, 2017;7(1):13139.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Tumor necrosis factor ? decreases aquaporin 3 expression in intestinal epithelial cells through inhibition of constitutive transcription
    Authors: MA Peplowski, AJ Vegso, V Iablokov, M Dicay, RS Zaheer, B Renaux, D Proud, MD Hollenberg, PL Beck, WK MacNaughto
    Physiol Rep, 2017;5(19):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Synovial cell death is regulated by TNF-?-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1?
    Authors: JW Lee, J Lee, SH Um, EY Moon
    Cell Death Dis, 2017;8(4):e2727.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. The autocrine role of proteoglycan-4 (PRG4) in modulating osteoarthritic synoviocyte proliferation and expression of matrix degrading enzymes
    Authors: A Alquraini, M Jamal, L Zhang, T Schmidt, GD Jay, KA Elsaid
    Arthritis Res. Ther., 2017;19(1):89.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. TNF?-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels
    Authors: AE van der Wi, IMC Vogels, CJF van Noorde, I Klaassen, RO Schlingema
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3496-3505.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Metabolic Adaptation Establishes Disease Tolerance to Sepsis
    Authors: S Weis, AR Carlos, MR Moita, S Singh, B Blankenhau, S Cardoso, R Larsen, S Rebelo, S Schäuble, L Del Barrio, G Mithieux, F Rajas, S Lindig, M Bauer, MP Soares
    Cell, 2017;169(7):1263-1275.e14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. The involvement and possible mechanism of pro-inflammatory tumor necrosis factor alpha (TNF-?) in thoracic ossification of the ligamentum flavum
    Authors: C Zhang, Z Chen, X Meng, M Li, L Zhang, A Huang
    PLoS ONE, 2017;12(6):e0178986.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  82. Diosgenin, an Activator of 1,25D3-MARRS Receptor/ERp57, Attenuates the Effects of TNF-? by Causing ADAM10-Dependent Ectodomain Shedding of TNF Receptor 1
    Authors: WS Yang, SY Moon, MJ Lee, EK Lee, SK Park
    Cell. Physiol. Biochem., 2017;43(6):2434-2445.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  83. A possible role for neutrophils in allergic rhinitis revealed after cellular subclassification
    Authors: J Arebro, S Ekstedt, E Hjalmarsso, O Winqvist, S Kumlien Ge, LO Cardell
    Sci Rep, 2017;7(0):43568.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A*33;03 for Cervical Cancer Immunotherapy
    Authors: Jong Baeck Lim
    Yonsei Med. J., 2017;58(1):43-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps
    Authors: BF Wang, PP Cao, ZC Wang, ZY Li, ZZ Wang, J Ma, B Liao, YK Deng, XB Long, K Xu, H Wang, H Wang, M Zeng, X Lu, Z Liu
    Allergy, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?
    Authors: JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, M Wittmann, M Stacey
    Proc. Natl. Acad. Sci. U.S.A, 2017;114(13):E2748-E2757.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Identification of benzazole compounds that induce HIV-1 transcription
    Authors: JD Graci, D Michaels, G Chen, GM Schiralli, S Nodder, M Weetall, GM Karp, Z Gu, JM Colacino, AJ Henderson
    PLoS ONE, 2017;12(6):e0179100.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
    Authors: S Zhu, Q Zhang, X Sun, HJ Zeh, MT Lotze, R Kang, D Tang
    Cancer Res, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Dendritic cells from rheumatoid arthritis patient peripheral blood induce Th17 cell differentiation via miR-363/Integrin ?v/TGF-? axis
    Authors: F Pan, H Xiang, J Yan, L Hong, L Zhang, Y Liu, X Feng, C Cai
    Scand. J. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. RalBP1 and p19-VHL play an oncogenic role, and p30-VHL plays a tumor suppressor role during the blebbishield emergency program
    Authors: GG Jinesh, AM Kamat
    Cell Death Discov, 2017;3(0):17023.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect
    Authors: BS Patel, MJ Kugel, G Baehring, AJ Ammit
    Pulm Pharmacol Ther, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  92. IFN-? and TNF-? synergism may provide a link between psoriasis and inflammatory atherogenesis
    Authors: NN Mehta, HL Teague, WR Swindell, Y Baumer, NL Ward, X Xing, B Baugous, A Johnston, AA Joshi, J Silverman, DH Barnes, L Wolterink, RP Nair, PE Stuart, M Playford, JJ Voorhees, MK Sarkar, JT Elder, K Gallagher, SK Ganesh, JE Gudjonsson
    Sci Rep, 2017;7(1):13831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Apomorphine suppresses TNF-?-induced MMP-9 expression and cell invasion through inhibition of ERK/AP-1 signaling pathway in MCF-7 cells
    Authors: YS Jung, SO Lee
    Biochem. Biophys. Res. Commun., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. HAT1 induces lung cancer cell apoptosis via up regulating Fas
    Authors: N Han, L Shi, Q Guo, W Sun, Y Yu, L Yang, X Zhang, M Zhang
    Oncotarget, 2017;8(52):89970-89977.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Decitabine treatment sensitizes tumor cells to T-cell-mediated cytotoxicity in patients with myelodysplastic syndromes
    Authors: Z Zhang, Q He, Y Tao, J Guo, F Xu, LY Wu, YS Zhao, D Wu, LY Zhou, JY Su, LX Song, C Xiao, X Li, CK Chang
    Am J Transl Res, 2017;9(2):454-465.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
    Authors: Y Haim, M Blüher, D Konrad, N Goldstein, N Klöting, I Harman-Boe, B Kirshtein, D Ginsberg, T Tarnovscki, Y Gepner, I Shai, A Rudich
    Mol Metab, 2017;6(7):725-736.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  97. IFN type I and II induce BAFF secretion from human decidual stromal cells
    Authors: AC Lundell, I Nordstr”m, K Andersson, C Lundqvist, E Telemo, S Nava, H Kaipe, A Rudin
    Sci Rep, 2017;7(0):39904.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology
    Authors: M Silva, RK Fung, CB Donnelly, PA Videira, R Sackstein
    J. Immunol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  99. A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors
    Authors: A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti
    JCI Insight, 2017;2(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques
    Authors: SR DiNapoli, AM Ortiz, F Wu, K Matsuda, HL Twigg, VM Hirsch, K Knox, JM Brenchley
    JCI Insight, 2017;2(4):e91214.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Frontline Science: c-Myc regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection
    Authors: R Connor, LD Jones, X Qiu, J Thakar, SB Maggirwar
    J. Leukoc. Biol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation
    Authors: T Tanaka, Y Zhou, T Ozawa, R Okizono, A Banba, T Yamamura, E Oga, A Muraguchi, H Sakurai
    J. Biol. Chem., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions
    Authors: X Wang, R Wilkinson, K Kildey, J Potriquet, J Mulvenna, RJ Lobb, A Möller, N Cloonan, P Mukhopadhy, AJ Kassianos, H Healy
    J Extracell Vesicles, 2017;6(1):1314073.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  104. MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866
    Authors: P Huang, MW Lee, K Sadrerafi, DP Heruth, LQ Zhang, D Maulik, SQ Ye
    Drug Des Devel Ther, 2017;11(0):629-641.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs)
    Authors: K Kinnunen, N Piippo, S Loukovaara, M Hytti, K Kaarnirant, A Kauppinen
    J Cell Commun Signal, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
    Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill,, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
    JCI Insight, 2017;2(17):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. Interleukin-20 is triggered by TLR ligands and associates with disease activity in patients with rheumatoid arthritis
    Authors: L Šenolt, K Prajzlerov, H Hulejová, B Šumová, M Filková, D Veigl, K Pavelka, J Vencovský
    Cytokine, 2017;97(0):187-192.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  108. A Synthetic Mammalian Therapeutic Gene Circuit for Sensing and Suppressing Inflammation
    Authors: A Smole, D Lain??ek, U Bezeljak, S Horvat, R Jerala
    Mol. Ther, 2017;25(1):102-119.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
    Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
    Stem Cell Res Ther, 2017;8(1):79.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Inhibition of the Receptor Tyrosine Kinase AXL Restores Paclitaxel Chemosensitivity in Uterine Serous Cancer
    Authors: ML Palisoul, JM Quinn, E Schepers, IS Hagemann, L Guo, K Reger, AR Hagemann, CK McCourt, PH Thaker, MA Powell, DG Mutch, KC Fuh
    Mol. Cancer Ther., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity
    Authors: D Sagar, NP Singh, R Ginwala, X Huang, R Philip, M Nagarkatti, P Nagarkatti, K Neumann, J Ruland, AM Andrews, SH Ramirez, ZK Khan, P Jain
    Sci Rep, 2017;7(1):2707.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells
    Authors: NT Hogan, MB Whalen, LK Stolze, NK Hadeli, MT Lam, JR Springstea, CK Glass, CE Romanoski
    Elife, 2017;6(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. iTRAQ quantitative proteomic study in patients with thoracic ossification of the ligamentum flavum
    Authors: B Wang, Z Chen, X Meng, M Li, X Yang, C Zhang
    Biochem. Biophys. Res. Commun., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  114. Suberanilohydroxamic Acid as a Pharmacological Kruppel-Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis
    Authors: Y Xu, S Xu, P Liu, M Koroleva, S Zhang, S Si, ZG Jin
    J Am Heart Assoc, 2017;6(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  115. In�vitro model of cerebral ischemia by using brain microvascular endothelial cells derived from human induced pluripotent stem cells
    Authors: Y Kokubu, T Yamaguchi, K Kawabata
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
    Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
    J. Immunol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. TNF? promotes proliferation of human synovial MSCs while maintaining chondrogenic potential
    Authors: M Shioda, T Muneta, K Tsuji, M Mizuno, K Komori, H Koga, I Sekiya
    PLoS ONE, 2017;12(5):e0177771.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Autophagy Impairment by Helicobacter pylori-induced Methylation Silencing of MAP1LC3Av1 Promotes Gastric Carcinogenesis
    Authors: JS Muhammad, S Nanjo, T Ando, S Yamashita, T Maekita, T Ushijima, Y Tabuchi, T Sugiyama
    Int. J. Cancer, 2017;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1
    Authors: J Yuzugulen, JA Douthwaite, EG Wood, IC Villar, NSA Patel, J Jegard, H Gaertner, I Rossitto-B, K Rose, O Hartley, PR Cutillas, A Ahluwalia, R Corder
    Sci Rep, 2017;7(1):4956.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells
    Authors: M Tanaka, H Tashiro, B Omer, N Lapteva, J Ando, M Ngo, B Mehta, G Dotti, PR Kinchingto, AM Leen, C Rossig, CM Rooney
    Clin. Cancer Res, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
    Authors: N Starc, D Ingo, A Conforti, V Rossella, L Tomao, A Pitisci, F De Mattia, I Brigida, M Algeri, M Montanari, G Palumbo, P Merli, P Rossi, A Aiuti, F Locatelli, ME Bernardo
    Sci Rep, 2017;7(1):8153.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  122. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells
    Authors: R Santos, KC Vadodaria, BN Jaeger, A Mei, S Lefcochilo, APD Mendes, G Erikson, M Shokhirev, L Randolph-M, C Fredlender, S Dave, R Oefner, C Fitzpatric, M Pena, JJ Barron, M Ku, AM Denli, BE Kerman, P Charnay, JR Kelsoe, MC Marchetto, FH Gage
    Stem Cell Reports, 2017;8(6):1757-1769.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  123. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
    Authors: KJ Chung, A Chatzigeor, M Economopou, R Garcia-Mar, VI Alexaki, I Mitroulis, M Nati, J Gebler, T Ziemssen, SE Goelz, J Phieler, JH Lim, KP Karalis, T Papayannop, M Blüher, G Hajishenga, T Chavakis
    Nat. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-?B-Activating Factors through Direct Downregulation of IKK? and IKK?
    Authors: MH Hancock, LM Hook, J Mitchell, JA Nelson
    MBio, 2017;8(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis
    Authors: J Retzlaff, K Thamm, CC Ghosh, W Ziegler, H Haller, SM Parikh, S David
    Sci Rep, 2017;7(0):44113.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Adipogenic differentiation of MSC alters their immunomodulatory properties in a tissue-specific manner
    Authors: H Munir, LS Ward, L Sheriff, S Kemble, S Nayar, F Barone, GB Nash, HM McGettrick
    Stem Cells, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  127. A double-negative feedback loop between EpCAM and ERK contributes to the regulation of epithelial-mesenchymal transition in cancer
    Authors: NV Sankpal, TP Fleming, PK Sharma, HJ Wiedner, WE Gillanders
    Oncogene, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Extracellular Microvesicle Production by Human Eosinophils Activated by Inflammatory Stimuli
    Authors: Rossana C N Melo
    Front Cell Dev Biol, 2016;4(0):117.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation
    Authors: Andrea Todisco
    Am. J. Physiol. Gastrointest. Liver Physiol., 2016;0(0):ajpgi.00169.2.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells
    Invest. Ophthalmol. Vis. Sci, 2016;57(15):6482-6495.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis.
    Authors: Lu W, Sun J, Yoon J, Zhang Y, Zheng L, Murphy E, Mattson M, Lenardo M
    PLoS ONE, 2016;11(1):e0147792.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization
    Mol Ther Methods Clin Dev, 2016;3(0):16056.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. IRAK1, a Target of miR-146b, Reduces Cell Aggressiveness of Human Papillary Thyroid Carcinoma
    J Clin Endocrinol Metab, 2016;0(0):jc20162276.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  134. Interferon-? and Tumor Necrosis Factor-? Polarize Bone Marrow Stromal Cells Uniformly to a Th1 Phenotype
    Sci Rep, 2016;6(0):26345.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells
    PLoS ONE, 2016;11(5):e0156145.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  136. IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  137. Environmental factor and inflammation-driven alteration of the total peripheral T-cell compartment in granulomatosis with polyangiitis
    Authors: Anja Kerstein
    J. Autoimmun, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex.
    Authors: Guo Z, Zheng L, Liao X, Geller D
    PLoS ONE, 2016;11(1):e0146640.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Roflumilast N-oxide in Combination with Formoterol Enhances the Anti-inflammatory Effect of Dexamethasone in ASM Cells
    Authors: Brijeshkumar S Patel
    Am. J. Respir. Cell Mol. Biol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement
    Authors: Michael A Schmid
    PLoS Pathog, 2016;12(6):e1005676.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  141. Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells
    PLoS ONE, 2016;11(12):e0167361.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.
    Authors: Divakar S, Ramana Reddy M, Cosenza S, Baker S, Perumal D, Antonelli A, Brody J, Akula B, Parekh S, Premkumar Reddy E
    Leukemia, 2016;30(1):86-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency
    Proc. Natl. Acad. Sci. U.S.A, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  144. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor ?1 expression
    Stem Cell Res Ther, 2016;7(1):175.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  145. MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations
    Authors: Robert Sabat
    Mediators Inflamm., 2016;2016(0):4097574.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17
    PLoS ONE, 2016;11(9):e0161759.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis
    Cell Death Dis, 2016;7(6):e2287.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  148. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population
    Authors: Derek N J Hart
    J. Immunol., 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Bioequivalence, safety and immunogenicity of BI 695501, an adalimumab biosimilar candidate, compared with the reference biologic in a randomized, double-blind, active-comparator Phase I clinical study (VOLTAIRE�-PK) in healthy subjects
    Authors: Niklas Czeloth
    Expert Opin Investig Drugs, 2016;0(0):.
    Applications: Bioassay
  150. Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7
    Authors: MM Halpert, V Konduri, D Liang, Y Chen, JB Wing, S Paust, JM Levitt, WK Decker
    Stem Cells Dev., 2016;25(10):774-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  151. HDL function is impaired in acute myocardial infarction independent of plasma HDL cholesterol levels
    Authors: Wijtske Annema
    J Clin Lipidol, 2016;10(6):1318-1328.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Anti-inflammatory and immunomodulatory effects of Aquaphilus dolomiae extract on in vitro models
    Authors: Nathalie Castex-Riz
    Clin Cosmet Investig Dermatol, 2016;9(0):421-434.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Endothelial Surface Protrusion by a Point Force
    Authors: Y Chen, L Lu, JY Shao
    Biophys. J, 2016;110(5):1150-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression
    Authors: Martin F Reiner
    Cardiovasc. Res, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling
    Sci Rep, 2016;6(0):39190.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  156. Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
    Authors: R Yosef, N Pilpel, R Tokarsky-A, A Biran, Y Ovadya, S Cohen, E Vadai, L Dassa, E Shahar, R Condiotti, I Ben-Porath, V Krizhanovs
    Nat Commun, 2016;7(0):11190.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  157. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    Cell, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  158. Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease
    Sci Rep, 2016;6(0):35282.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Endothelial Cell Activation is Regulated by Epidermal Growth Factor-Like Domain 7 (Egfl7) during Inflammation
    J Biol Chem, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme
    Authors: Joan W Conaway
    J. Biol. Chem., 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
    Nat Commun, 2016;7(0):12951.
    Species: Ovine
    Sample Types: Whole Tissue
    Applications: Bioassay
  162. Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study
    Authors: O Freynet, J Marchal-So, F Jean-Louis, A Mailleux, B Crestani, P Soler, L Michel
    Respir Res, 2016;17(1):36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Anti-inflammatory treatment improves high-density lipoprotein function in rheumatoid arthritis
    Authors: John Deanfield
    Heart, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  164. A Common Genetic Variant in TLR1 Enhances Human Neutrophil Priming and Impacts Length of Intensive Care Stay in Pediatric Sepsis.
    Authors: Whitmore L, Hook J, Philiph A, Hilkin B, Bing X, Ahn C, Wong H, Ferguson P, Moreland J
    J Immunol, 2016;196(3):1376-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Bradykinin stimulates protein kinase D-mediated colonic myofibroblast migration via cyclooxygenase-2 and heat shock protein 27
    Authors: Eric Chu
    J. Surg. Res, 2016;209(0):191-198.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Mycobacterium massiliense Induces Macrophage Extracellular Traps with Facilitating Bacterial Growth
    PLoS ONE, 2016;11(5):e0155685.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  167. Adsorption as a Contributor for Inflammatory Mediators Removal by Different Hemofiltration Membranes: A Pilot Study
    Authors: Benjamin Malard
    Artif Organs, 2016;0(0):.
    Species: Human
    Sample Types: Plasma
    Applications: Hemofiltration Procedure
  168. IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling
    Authors: R Liu, C Tang, A Shen, H Luo, X Wei, D Zheng, C Sun, Z Li, D Zhu, T Li, Z Wu
    Oncotarget, 2016;7(51):85079-85096.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
    Authors: Shailesh Dudhgaonka
    J. Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  170. Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting beta(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligands.
    Authors: Rider C, Shah S, Miller-Larsson A, Giembycz M, Newton R
    PLoS ONE, 2015;10(1):e0116773.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  171. L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro.
    Authors: Rzeniewicz K, Newe A, Rey Gallardo A, Davies J, Holt M, Patel A, Charras G, Stramer B, Molenaar C, Tedder T, Parsons M, Ivetic A
    Proc Natl Acad Sci U S A, 2015;112(12):E1461-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  172. Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome.
    Authors: Fairclough L, Stoop A, Negm O, Radford P, Tighe P, Todd I
    Eur J Immunol, 2015;45(10):2937-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage.
    Authors: Catanzaro D, Rancan S, Orso G, Dall'Acqua S, Brun P, Giron M, Carrara M, Castagliuolo I, Ragazzi E, Caparrotta L, Montopoli M
    PLoS ONE, 2015;10(5):e0125375.
  174. Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes.
    Authors: Sommerfelt R, Feuerherm A, Skuland T, Johansen B
    PLoS ONE, 2015;10(4):e0119088.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  175. RelB/p50 complexes regulate cytokine-induced YKL-40 expression.
    Authors: Bhardwaj R, Yester J, Singh S, Biswas D, Surace M, Waters M, Hauser K, Yao Z, Boyce B, Kordula T
    J Immunol, 2015;194(6):2862-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  176. IL-4 Downregulates IL-1beta and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine.
    Authors: Onderdijk A, Baerveldt E, Kurek D, Kant M, Florencia E, Debets R, Prens E
    J Immunol, 2015;195(4):1744-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.
    Authors: Boisson B, Laplantine E, Dobbs K, Cobat A, Tarantino N, Hazen M, Lidov H, Hopkins G, DU L, Belkadi A, Chrabieh M, Itan Y, Picard C, Fournet J, Eibel H, Tsitsikov E, Pai S, Abel L, Al-Herz W, Casanova J, Israel A, Notarangelo L
    J Exp Med, 2015;212(6):939-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
    Authors: Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, Schaeren-Wiemers N, Du Pasquier R
    J Neuroinflammation, 2015;12(0):119.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma.
    Authors: Yousef S, Heise J, Lajmi N, Bartels K, Kroger N, Luetkens T, Atanackovic D
    J Transl Med, 2015;13(0):197.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment.
    Authors: Rousseau M, Belleannee C, Duchez A, Cloutier N, Levesque T, Jacques F, Perron J, Nigrovic P, Dieude M, Hebert M, Gelb M, Boilard E
    PLoS ONE, 2015;10(1):e0116812.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor kappaB (NF-kappaB) signaling.
    Authors: Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, Zhang Y, Guo S, Qin X, Li T, Li W, Li A, Zhang X, Li H
    J Biol Chem, 2015;290(16):10395-405.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Oncogenic Transformation Can Orchestrate Immune Evasion and Inflammation in Human Mesenchymal Stem Cells Independently of Extrinsic Immune-Selective Pressure.
    Authors: Miranda A, Funes J, Sanchez N, Limia C, Mesa M, Quezada S, Perez R, de Leon J
    Cancer Res, 2015;75(15):3032-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. CYLD and the NEMO Zinc Finger Regulate Tumor Necrosis Factor Signaling and Early Embryogenesis.
    Authors: Zhao Y, Ma C, Wu L, Iwai K, Ashwell J, Oltz E, Ballard D, Jain A
    J Biol Chem, 2015;290(36):22076-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Facile supermolecular aptamer inhibitors of L-selectin.
    Authors: Chang, Elizabet, Eckert, Mark A, Ali, M Monsur, Riazifar, Hamidrez, Pone, Egest J, Liu, Linan, Zhao, Weian
    PLoS ONE, 2015;10(3):e0123034.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Anti-apoptotic NF-kappaB and "gain of function" mutp53 in concert act pro-apoptotic in response to UVB+IL-1 via enhanced TNF production.
    Authors: Muller I, Beissert S, Kulms D
    J Invest Dermatol, 2015;135(3):851-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Molecular mechanisms linking high dose medroxyprogesterone with HIV-1 risk.
    Authors: Irvin S, Herold B
    PLoS ONE, 2015;10(3):e0121135.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.
    Authors: Watson R, Buck J, Levin L, Winger R, Wang J, Arase H, Muller W
    J Exp Med, 2015;212(7):1021-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Role of transforming growth factor-activated kinase-1 on tumor necrosis factor-alpha actions in human adipose tissue-derived stromal cells.
    Authors: Lee S, Lee J, Shin K, Kim D, Kim Y, Bae Y, Jung J
    Stem Cells Dev, 2015;24(7):836-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
    Authors: Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M
    Invest Ophthalmol Vis Sci, 2015;56(2):1051-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
    Authors: Lam, Sharon, Sung, Julia, Cruz, Conrad, Castillo-Caro, Paul, Ngo, Minhtran, Garrido, Carolina, Kuruc, Joann, Archin, Nancie, Rooney, Cliona, Margolis, David, Bollard, Catherin
    Mol Ther, 2015;23(2):387-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  191. Tissue Inhibitor of Metalloproteinase-4 Triggers Apoptosis in Cervical Cancer Cells.
    Authors: Lizarraga F, Ceballos-Cancino G, Espinosa M, Vazquez-Santillan K, Maldonado V, Melendez-Zajgla J
    PLoS ONE, 2015;10(8):e0135929.
  192. BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak-STAT signaling in a gene-specific manner in human monocytes.
    Authors: Chan C, Fang C, Qiao Y, Yarilina A, Prinjha R, Ivashkiv L
    Eur J Immunol, 2015;45(1):287-97.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function.
    Authors: Leslie J, Huang S, Opp J, Nagy M, Kobayashi M, Young V, Spence J
    Infect Immun, 2015;83(1):138-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein delta.
    Authors: Yamaguchi J, Tanaka T, Eto N, Nangaku M
    Kidney Int, 2015;88(2):262-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  195. The cerebral cavernous malformation 3 gene is necessary for senescence induction.
    Authors: Guerrero A, Iglesias C, Raguz S, Floridia E, Gil J, Pombo C, Zalvide J
    Aging Cell, 2015;14(2):274-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  196. 6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NFkappaB activation in airway epithelial cells.
    Authors: Kurakula K, Hamers A, van Loenen P, de Vries C
    Respir Res, 2015;16(0):73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Nuclear FAM21 participates in NF-kappaB-dependent gene regulation in pancreatic cancer cells.
    Authors: Deng Z, Gomez T, Osborne D, Phillips-Krawczak C, Zhang J, Billadeau D
    J Cell Sci, 2015;128(2):373-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  198. RIP1 Kinase Is an Oncogenic Driver in Melanoma.
    Authors: Liu X, Lai F, Yan X, Jiang C, Guo S, Wang C, Croft A, Tseng H, Wilmott J, Scolyer R, Jin L, Zhang X
    Cancer Res, 2015;75(8):1736-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  199. The effect of protease inhibitors on the induction of osteoarthritis-related biomarkers in bovine full-depth cartilage explants.
    Authors: He Y, Zheng Q, Jiang M, Sun S, Christiansen T, Kassem M, Karsdal M, Bay-Jensen A
    PLoS ONE, 2015;10(0):.
    Species: Bovine
    Sample Types: Whole Tissue
    Applications: Bioassay
  200. PHLDA1 expression is controlled by an estrogen receptor-NFkappaB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres.
    Authors: Kastrati I, Canestrari E, Frasor J
    Oncogene, 2015;34(18):2309-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Th17-type cytokines, IL-6 and TNF-alpha synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.
    Authors: De Simone V, Franze E, Ronchetti G, Colantoni A, Fantini M, Di Fusco D, Sica G, Sileri P, MacDonald T, Pallone F, Monteleone G, Stolfi C
    Oncogene, 2015;34(27):3493-503.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Interleukin-2 alters distribution of CD144 (VE-cadherin) in endothelial cells.
    Authors: Kim, Dae Won, Zloza, Andrew, Broucek, Joseph, Schenkel, Jason M, Ruby, Carl, Samaha, Georges, Kaufman, Howard L
    J Transl Med, 2014;12(0):113.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-alpha, and IL-1beta.
    Authors: Zhao Y, Xiao X, Frank S, Lin H, Xia Y
    Am J Physiol Endocrinol Metab, 2014;307(2):E186-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. IL-2 phosphorylates STAT5 to drive IFN-gamma production and activation of human dendritic cells.
    Authors: Herr F, Lemoine R, Gouilleux F, Meley D, Kazma I, Heraud A, Velge-Roussel F, Baron C, Lebranchu Y
    J Immunol, 2014;192(12):5660-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. Vaspin inhibits cytokine-induced nuclear factor-kappa B activation and adhesion molecule expression via AMP-activated protein kinase activation in vascular endothelial cells.
    Authors: Jung C, Lee M, Kang Y, Lee Y, Yoon H, Kang S, Lee W, Park J
    Cardiovasc Diabetol, 2014;13(0):41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.
    Authors: Milwid, Jack M, Elman, Jessica, Li, Matthew, Shen, Keyue, Manrai, Arjun, Gabow, Aaron, Yarmush, Joshua, Jiao, Yunxin, Fletcher, Anne, Lee, Jungwoo, Cima, Michael, Yarmush, Martin L, Parekkadan, Biju
    Mol Ther, 2014;22(5):999-1007.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  207. p38-Mediated phosphorylation of Eps15 endocytic adaptor protein.
    Authors: Zhou Y, Tanaka T, Sugiyama N, Yokoyama S, Kawasaki Y, Sakuma T, Ishihama Y, Saiki I, Sakurai H
    FEBS Lett, 2014;588(1):131-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation.
    Authors: Sato J, Kinugasa M, Satomi-Kobayashi S, Hatakeyama K, Knox A, Asada Y, Wierman M, Hirata K, Rikitake Y
    PLoS ONE, 2014;9(9):e107236.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways.
    Authors: Chiang, En-Pei I, Tsai, Shu-Yao, Kuo, Yueh-Hsi, Pai, Man-Hui, Chiu, Hsi-Lin, Rodriguez, Raymond, Tang, Feng-Yao
    PLoS ONE, 2014;9(6):e99631.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity.
    Authors: Morlino G, Barreiro O, Baixauli F, Robles-Valero J, Gonzalez-Granado J, Villa-Bellosta R, Cuenca J, Sanchez-Sorzano C, Veiga E, Martin-Cofreces N, Sanchez-Madrid F
    Mol Cell Biol, 2014;34(8):1412-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members.
    Authors: Beigel F, Friedrich M, Probst C, Sotlar K, Goke B, Diegelmann J, Brand S
    PLoS ONE, 2014;9(4):e93498.
    Species: N/A
    Sample Types: N/A
    Applications: WB Standard
  212. Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.
    Authors: Ohlsson S, Ohlsson S, Soderberg D, Gunnarsson L, Pettersson A, Segelmark M, Hellmark T
    Clin Exp Immunol, 2014;176(3):363-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis.
    Authors: Dalli, Jesmond, Norling, Lucy V, Montero-Melendez, Trinidad, Federici Canova, Donata, Lashin, Hazem, Pavlov, Anton M, Sukhorukov, Gleb B, Hinds, Charles, Perretti, Mauro
    EMBO Mol Med, 2014;6(1):27-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3.
    Authors: Hu M, Yang Q, Zhang J, Liu S, Zhang Y, Lin H, Huang Z, Wang Y, Zhang X, Zhong B, Shu H
    Proc Natl Acad Sci U S A, 2014;111(4):1509-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  215. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion.
    Authors: Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L
    PLoS ONE, 2014;9(9):e106673.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  216. Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels.
    Authors: You B, Park W
    Int J Oncol, 2014;44(5):1745-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Functional effects of Toll-like receptor (TLR)3, 7, 9, RIG-I and MDA-5 stimulation in nasal epithelial cells.
    Authors: Tengroth L, Millrud C, Kvarnhammar A, Kumlien Georen S, Latif L, Cardell L
    PLoS ONE, 2014;9(6):e98239.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  218. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
    Authors: Sidney L, Kirkham G, Buttery L
    Stem Cells Dev, 2014;23(6):605-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids.
    Authors: Rahman M, Alkhouri H, Tang F, Che W, Ge Q, Ammit A
    PLoS ONE, 2014;9(3):e92466.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  220. Tumor necrosis factor (TNF)-alpha induction of CXCL10 in endothelial cells requires protein arginine methyltransferase 5 (PRMT5)-mediated nuclear factor (NF)-kappaB p65 methylation.
    Authors: Harris D, Bandyopadhyay S, Maxwell T, Willard B, DiCorleto P
    J Biol Chem, 2014;289(22):15328-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Luteolin inhibits human keratinocyte activation and decreases NF-kappaB induction that is increased in psoriatic skin.
    Authors: Weng Z, Patel A, Vasiadi M, Therianou A, Theoharides T
    PLoS ONE, 2014;9(2):e90739.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity.
    Authors: Schafer P, Parton A, Capone L, Cedzik D, Brady H, Evans J, Man H, Muller G, Stirling D, Chopra R
    Cell Signal, 2014;26(9):2016-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  223. A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS).
    Authors: Negm O, Mannsperger H, McDermott E, Drewe E, Powell R, Todd I, Fairclough L, Tighe P
    Eur J Immunol, 2014;44(7):2096-110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  224. The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling.
    Authors: Wu L, Wang C, Boisson B, Misra S, Rayman P, Finke J, Puel A, Casanova J, Li X
    J Immunol, 2014;193(4):1590-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  225. Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death.
    Authors: Ji, Weidong, Yang, Mei, Praggastis, Alexandr, Li, Yonghao, Zhou, Huanjiao, He, Yun, Ghazvinian, Roxanne, Cincotta, Dylan J, Rice, Kevin P, Min, Wang
    PLoS ONE, 2014;9(7):e103224.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Absence of a role for interleukin-13 in inflammatory bowel disease.
    Authors: Biancheri P, Di Sabatino A, Ammoscato F, Facciotti F, Caprioli F, Curciarello R, Hoque S, Ghanbari A, Joe-Njoku I, Giuffrida P, Rovedatti L, Geginat J, Corazza G, MacDonald T
    Eur J Immunol, 2014;44(2):370-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Osteodifferentiated mesenchymal stem cells from bone marrow and adipose tissue express HLA-G and display immunomodulatory properties in HLA-mismatched settings: implications in bone repair therapy.
    Authors: Montespan F, Deschaseaux F, Sensebe L, Carosella E, Rouas-Freiss N
    J Immunol Res, 2014;2014(0):230346.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-alpha-induced procoagulant activity and apoptosis in endothelial cells.
    Authors: Ohkawara H, Ishibashi T, Sugimoto K, Ikeda K, Ogawa K, Takeishi Y
    PLoS ONE, 2014;9(8):e105697.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Plasma cells in the mucosa of patients with inflammatory bowel disease produce granzyme B and possess cytotoxic activities.
    Authors: Cupi M, Sarra M, Marafini I, Monteleone I, Franze E, Ortenzi A, Colantoni A, Sica G, Sileri P, Rosado M, Carsetti R, MacDonald T, Pallone F, Monteleone G
    J Immunol, 2014;192(12):6083-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  230. Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential.
    Authors: Cubbon R, Yuldasheva N, Viswambharan H, Mercer B, Baliga V, Stephen S, Askham J, Sukumar P, Skromna A, Mughal R, Walker A, Bruns A, Bailey M, Galloway S, Imrie H, Gage M, Rakobowchuk M, Li J, Porter K, Ponnambalam S, Wheatcroft S, Beech D, Kearney M
    Stem Cells, 2014;32(10):2714-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer.
    Authors: Kim S, Chung H, Lee K, Lim J
    J Transl Med, 2014;12(0):229.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation.
    Authors: Mambetsariev I, Tian Y, Wu T, Lavoie T, Solway J, Birukov K, Birukova A
    PLoS ONE, 2014;9(4):e92670.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable pancreatic cancer.
    Authors: Shindo Y, Hazama S, Maeda Y, Matsui H, Iida M, Suzuki N, Yoshimura K, Ueno T, Yoshino S, Sakai K, Suehiro Y, Yamasaki T, Hinoda Y, Oka M
    J Transl Med, 2014;12(0):175.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.
    Authors: Singer B, Opp L, Heinrich A, Schreiber F, Binding-Liermann R, Berrocal-Almanza L, Heyl K, Muller M, Weimann A, Zweigner J, Slevogt H
    PLoS ONE, 2014;9(4):e94106.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  235. Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.
    Authors: Suzuki, Hitoshi, Raska, Milan, Yamada, Koshi, Moldoveanu, Zina, Julian, Bruce A, Wyatt, Robert J, Tomino, Yasuhiko, Gharavi, Ali G, Novak, Jan
    J Biol Chem, 2014;289(8):5330-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Endothelial activation by platelets from sickle cell anemia patients.
    Authors: Proenca-Ferreira R, Brugnerotto A, Garrido V, Dominical V, Vital D, Ribeiro M, dos Santos M, Traina F, Olalla-Saad S, Costa F, Conran N
    PLoS ONE, 2014;9(2):e89012.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk.
    Authors: Sehgal K, Ragheb R, Fahmy T, Dhodapkar M, Dhodapkar K
    J Immunol, 2014;193(5):2297-305.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, alpha-Ketoglutarate (alpha-KG), and DNA hydroxymethylation levels by interleukin-1beta in primary human chondrocytes.
    Authors: Haseeb A, Makki M, Haqqi T
    J Biol Chem, 2014;289(10):6877-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.
    Authors: Bailon E, Ugarte-Berzal E, Amigo-Jimenez I, Van den Steen P, Opdenakker G, Garcia-Marco J, Garcia-Pardo A
    J Leukoc Biol, 2014;96(2):185-99.
    Species: Human
    Sample Types: N/A
    Applications: Not Specified
  240. Characterization of platelet-monocyte complexes in HIV-1-infected individuals: possible role in HIV-associated neuroinflammation.
    Authors: Singh, Meera V, Davidson, Donna C, Jackson, Joseph W, Singh, Vir B, Silva, Jharon, Ramirez, Servio H, Maggirwar, Sanjay B
    J Immunol, 2014;192(10):4674-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Influence of proinflammatory stimuli on the expression of vascular ribonuclease 1 in endothelial cells.
    Authors: Gansler J, Preissner K, Fischer S
    FASEB J, 2014;28(2):752-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  242. CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis.
    Authors: Parlato M, Souza-Fonseca-Guimaraes F, Philippart F, Misset B, Adib-Conquy M, Cavaillon J
    J Immunol, 2014;192(5):2449-59.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  243. Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M.
    Authors: Rabeony H, Petit-Paris I, Garnier J, Barrault C, Pedretti N, Guilloteau K, Jegou J, Guillet G, Huguier V, Lecron J, Bernard F, Morel F
    PLoS ONE, 2014;9(7):e101937.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  244. High activities of BACE1 in brains with mild cognitive impairment.
    Authors: Cheng X, He P, Lee T, Yao H, Li R, Shen Y
    Am J Pathol, 2014;184(1):141-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Pharmacologic IKK/NF-kappaB inhibition causes antigen presenting cells to undergo TNFalpha dependent ROS-mediated programmed cell death.
    Authors: Tilstra J, Gaddy D, Zhao J, Dave S, Niedernhofer L, Plevy S, Robbins P
    Sci Rep, 2014;4(0):3631.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  246. A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells.
    Authors: Ugarte-Berzal E, Bailon E, Amigo-Jimenez I, Albar J, Garcia-Marco J, Garcia-Pardo A
    J Biol Chem, 2014;289(22):15340-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  247. A20 deficiency causes spontaneous neuroinflammation in mice.
    Authors: Guedes R, Csizmadia E, Moll H, Ma A, Ferran C, da Silva C
    J Neuroinflammation, 2014;11(0):122.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Stimulation
  248. Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal.
    Authors: Salzano S, Checconi P, Hanschmann E, Lillig C, Bowler L, Chan P, Vaudry D, Mengozzi M, Coppo L, Sacre S, Atkuri K, Sahaf B, Herzenberg L, Herzenberg L, Mullen L, Ghezzi P
    Proc Natl Acad Sci U S A, 2014;111(33):12157-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  249. Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis.
    Authors: Cucchiarini M, Madry H, Terwilliger E
    J Cell Mol Med, 2014;18(1):115-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition.
    Authors: Mimura N, Hideshima T, Shimomura T, Suzuki R, Ohguchi H, Rizq O, Kikuchi S, Yoshida Y, Cottini F, Jakubikova J, Cirstea D, Gorgun G, Minami J, Tai Y, Richardson P, Utsugi T, Iwama A, Anderson K
    Cancer Res, 2014;74(16):4458-69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  251. A composite model of the human postcapillary venule for investigation of microvascular leukocyte recruitment.
    Authors: Lauridsen H, Pober J, Gonzalez A
    FASEB J, 2014;28(3):1166-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  252. MicroRNA-26b suppresses the NF-kappaB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3.
    Authors: Zhao N, Wang R, Zhou L, Zhu Y, Gong J, Zhuang S
    Mol Cancer, 2014;13(0):35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Transcriptional repression of the transforming growth factor beta (TGF-beta) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor kappaB (NF-kappaB) p50 enhances TGF-beta signaling in hepatic stellate cells.
    Authors: Liu C, Chen X, Yang L, Kisseleva T, Brenner D, Seki E
    J Biol Chem, 2014;289(10):7082-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  254. Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB231 partly through suppression of the Akt pathway.
    Authors: Jin H, Lee W, Eun S, Jung J, Park H, Kim G, Choi Y, Ryu C, Jung J, Hong S, Shin S, Kim H
    Int J Oncol, 2014;45(4):1629-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Tumor necrosis factor stimulates osteoclastogenesis from human bone marrow cells under hypoxic conditions.
    Authors: Nomura T, Aoyama M, Waguri-Nagaya Y, Goto Y, Suzuki M, Miyazawa K, Asai K, Goto S
    Exp Cell Res, 2014;321(2):167-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  256. DeltaNp63 controls a TLR3-mediated mechanism that abundantly provides thymic stromal lymphopoietin in atopic dermatitis.
    Authors: Kubo T, Kamekura R, Kumagai A, Kawata K, Yamashita K, Mitsuhashi Y, Kojima T, Sugimoto K, Yoneta A, Sumikawa Y, Yamashita T, Sato N, Himi T, Ichimiya S
    PLoS ONE, 2014;9(8):e105498.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  257. Cell density impacts epigenetic regulation of cytokine-induced E-selectin gene expression in vascular endothelium.
    Authors: Hamada K, Osaka M, Yoshida M
    PLoS ONE, 2014;9(4):e90502.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  258. p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-kappaB subunit.
    Authors: O'Hara A, Simpson J, Morin P, Loveridge C, Williams A, Novo S, Stark L
    J Cell Sci, 2014;127(0):3659-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  259. The in vitro pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long acting beta2-adrenoceptor agonist.
    Authors: Tannheimer S, Sorensen E, Cui Z, Kim M, Patel L, Baker W, Phillips G, Wright C, Salmon M
    J Pharmacol Exp Ther, 2014;349(1):85-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  260. MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
    Authors: Lopez-Ramirez M, Wu D, Pryce G, Simpson J, Reijerkerk A, King-Robson J, Kay O, de Vries H, Hirst M, Sharrack B, Baker D, Male D, Michael G, Romero I
    FASEB J, 2014;28(6):2551-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.
    Authors: Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, Barra C, Comerma L, Chudnovskiy A, Gentile M, Llige D, Cols M, Serrano S, Arostegui J, Juan M, Yague J, Merad M, Fagarasan S, Cerutti A
    Nat Immunol, 2014;15(4):354-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  262. Glucocorticoid-induced reversal of interleukin-1beta-stimulated inflammatory gene expression in human oviductal cells.
    Authors: Backman S, Kollara A, Haw R, Stein L, Brown T
    PLoS ONE, 2014;9(5):e97997.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD.
    Authors: Chattopadhyay A, Hood B, Conrads T, Redner R
    Mol Cancer Res, 2014;12(9):1283-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  264. Toxoplasma gondii virulence factor ROP18 inhibits the host NF-kappaB pathway by promoting p65 degradation.
    Authors: Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J
    J Biol Chem, 2014;289(18):12578-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Novel ex vivo culture method for human monocytes uses shear flow to prevent total loss of transendothelial diapedesis function.
    Authors: Tsubota Y, Frey J, Raines E
    J Leukoc Biol, 2014;95(1):191-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  266. TNF-alpha induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways.
    Authors: Lo H, Lai T, Li C, Wu W
    Acta Pharmacol Sin, 2014;35(3):339-50.
  267. Tumour necrosis factor-alpha regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-kappaB and AP-1.
    Authors: Kankaanranta H, Ilmarinen P, Zhang X, Adcock I, Lahti A, Barnes P, Giembycz M, Lindsay M, Moilanen E
    PLoS ONE, 2014;9(2):e90298.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  268. Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy.
    Authors: Ahmad T, Mukherjee S, Pattnaik B, Kumar M, Singh S, Kumar M, Rehman R, Tiwari B, Jha K, Barhanpurkar A, Wani M, Roy S, Mabalirajan U, Ghosh B, Agrawal A
    EMBO J, 2014;33(9):994-1010.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  269. A splicing variant of NME1 negatively regulates NF-kappaB signaling and inhibits cancer metastasis by interacting with IKKbeta.
    Authors: You D, Park C, Lee H, Moon M, Kang J, Lee C, Oh S, Ahn C, Seong J, Hwang J
    J Biol Chem, 2014;289(25):17709-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivation.
    Authors: Duverger, Alexandr, Wolschendorf, Frank, Anderson, Joshua C, Wagner, Frederic, Bosque, Alberto, Shishido, Takao, Jones, Jennifer, Planelles, Vicente, Willey, Christop, Cron, Randall, Kutsch, Olaf
    J Virol, 2014;88(1):364-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  271. IDO-independent suppression of T cell effector function by IFN-gamma-licensed human mesenchymal stromal cells.
    Authors: Chinnadurai R, Copland I, Patel S, Galipeau J
    J Immunol, 2014;192(4):1491-501.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Rad GTPase inhibits the NFkappaB pathway through interacting with RelA/p65 to impede its DNA binding and target gene transactivation.
    Authors: Hsiao B, Chang T, Wu I, Chen M
    Cell Signal, 2014;26(7):1437-44.
  273. TRAIL/DR5 signaling promotes macrophage foam cell formation by modulating scavenger receptor expression.
    Authors: Liu F, Wu X, Zhang Y, Wang Y, Jiang F
    PLoS ONE, 2014;9(1):e87059.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  274. The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.
    Authors: Lessey-Morillon E, Osborne L, Monaghan-Benson E, Guilluy C, O'Brien E, Superfine R, Burridge K
    J Immunol, 2014;192(7):3390-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  275. TNF-alpha blockade induces IL-10 expression in human CD4+ T cells.
    Authors: Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L
    Nat Commun, 2014;5(0):3199.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  276. TNF-alpha induces matrix metalloproteinase-9-dependent soluble intercellular adhesion molecule-1 release via TRAF2-mediated MAPKs and NF-kappaB activation in osteoblast-like MC3T3-E1 cells.
    Authors: Tsai C, Chen W, Hsieh H, Chi P, Hsiao L, Yang C
    J Biomed Sci, 2014;21(0):12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  277. Durable remission of renal cell carcinoma in conjuncture with graft versus host disease following allogeneic stem cell transplantation and donor lymphocyte infusion: rule or exception?
    Authors: van Bergen, Cornelis, Verdegaal, Elisabet, Honders, M Wilhel, Hoogstraten, Conny, Steijn-van Tol, A Q M Je, de Quartel, Linda, de Jong, Joan, Meyering, Maaike, Falkenburg, J H Fred, Griffioen, Marieke, Osanto, Susanne
    PLoS ONE, 2014;9(1):e85198.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  278. A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.
    Authors: Lewis, Nuruddee, Patnaude, Lori A, Pelletier, Josephin, Souza, Donald J, Lukas, Susan M, King, F James, Hill, Jonathan, Stefanopoulos, Dimitria, Ryan, Kelli, Desai, Sudha, Skow, Donna, Kauschke, Stefan G, Broermann, Andre, Kuzmich, Daniel, Harcken, Christia, Hickey, Eugene R, Modis, Louise K
    PLoS ONE, 2014;9(6):e100883.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  279. Overexpression of CCN3 inhibits inflammation and progression of atherosclerosis in apolipoprotein E-deficient mice.
    Authors: Liu J, Ren Y, Kang L, Zhang L
    PLoS ONE, 2014;9(4):e94912.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  280. Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis.
    Authors: Volpe E, Pattarini L, Martinez-Cingolani C, Meller S, Donnadieu M, Bogiatzi S, Fernandez M, Touzot M, Bichet J, Reyal F, Paronetto M, Chiricozzi A, Chimenti S, Nasorri F, Cavani A, Kislat A, Homey B, Soumelis V
    J Allergy Clin Immunol, 2014;134(2):373-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  281. Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4.
    Authors: Catanzaro J, Sheshadri N, Pan J, Sun Y, Shi C, Li J, Powers R, Crawford H, Zong W
    Nat Commun, 2014;5(0):3729.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  282. IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.
    Authors: Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, Behar S
    J Immunol, 2013;190(8):4196-204.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation.
    Authors: Narayanan R, Yepuru M, Coss C, Wu Z, Bauler M, Barrett C, Mohler M, Wang Y, Kim J, Snyder L, He Y, Levy N, Miller D, Dalton J
    PLoS ONE, 2013;8(12):e83380.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration.
    Authors: Rossi E, Sanz-Rodriguez F, Eleno N, Duwell A, Blanco F, Langa C, Botella L, Cabanas C, Lopez-Novoa J, Bernabeu C
    Blood, 2013;121(2):403-15.
  285. Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma.
    Authors: Zheng Y, McFarland B, Drygin D, Yu H, Bellis S, Kim H, Bredel M, Benveniste E
    Clin Cancer Res, 2013;19(23):6484-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: cell culture
  286. In vivo modulation of the inflammatory response by nonsteroidal antiinflammatory drug-related compounds that trigger L-selectin shedding.
    Authors: Herrera-Garcia A, Dominguez-Luis M, Arce-Franco M, Lopez-Fernandez J, Feria M, Barreiro O, Sanchez-Madrid F, Diaz-Gonzalez F
    Eur J Immunol, 2013;43(1):55-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  287. 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.
    Authors: Mabalirajan U, Rehman R, Ahmad T, Kumar S, Leishangthem G, Singh S, Dinda A, Biswal S, Agrawal A, Ghosh B
    Sci Rep, 2013;3(0):1540.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  288. Long-term incubation with proteasome inhibitors (PIs) induces IkappaBalpha degradation via the lysosomal pathway in an IkappaB kinase (IKK)-dependent and IKK-independent manner.
    Authors: Lee K, Jeong J, Yoo C
    J Biol Chem, 2013;288(45):32777-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  289. Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection.
    Authors: Fraietta J, Mueller Y, Yang G, Boesteanu A, Gracias D, Do D, Hope J, Kathuria N, McGettigan S, Lewis M, Giavedoni L, Jacobson J, Katsikis P
    PLoS Pathog, 2013;9(10):e1003658.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Magnolol inhibits migration of vascular smooth muscle cells via cytoskeletal remodeling pathway to attenuate neointima formation.
    Authors: Karki R, Kim S, Kim D
    Exp Cell Res, 2013;319(20):3238-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice.
    Authors: Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R
    J Biol Chem, 2013;288(3):1953-66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Media Supplement - Cell Prep
  292. Tumor necrosis factor alpha-induced microRNA-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NF-kappaB signaling.
    Authors: Trenkmann M, Brock M, Gay R, Michel B, Gay S, Huber L
    Arthritis Rheum, 2013;65(4):916-27.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  293. Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18.
    Authors: Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, Tanaka Y, Okamura H
    PLoS ONE, 2013;8(12):e82586.
    Species: Human
    Sample Types: N/A
    Applications: Not Specified
  294. Outer membrane vesicles derived from Escherichia coli up-regulate expression of endothelial cell adhesion molecules in vitro and in vivo.
    Authors: Kim J, Yoon Y, Lee J, Choi E, Yi N, Park K, Park J, Lotvall J, Kim Y, Gho Y
    PLoS ONE, 2013;8(3):e59276.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes.
    Authors: Sommerfelt R, Feuerherm A, Jones K, Johansen B
    PLoS ONE, 2013;8(12):e83555.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  296. MUC1 and MUC13 differentially regulate epithelial inflammation in response to inflammatory and infectious stimuli.
    Authors: Sheng Y, Triyana S, Wang R, Das I, Gerloff K, Florin T, Sutton P, McGuckin M
    Mucosal Immunol, 2013;6(3):557-68.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  297. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics.
    Authors: Rapicavoli N, Qu K, Zhang J, Mikhail M, Laberge R, Chang H
    Elife, 2013;2(0):e00762.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  298. The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytes.
    Authors: Mercier S, Donaghy H, Botting R, Turville S, Harman A, Nasr N, Ji H, Kusebauch U, Mendoza L, Shteynberg D, Sandgren K, Simpson R, Moritz R, Cunningham A
    PLoS Pathog, 2013;9(10):e1003700.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
    Authors: Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M
    J Exp Med, 2013;211(2):263-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  300. The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells.
    Authors: Fiorcari S, Brown W, McIntyre B, Estrov Z, Maffei R, O'Brien S, Sivina M, Hoellenriegel J, Wierda W, Keating M, Ding W, Kay N, Lannutti B, Marasca R, Burger J
    PLoS ONE, 2013;8(12):e83830.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  301. NF-kappaB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma.
    Authors: McFarland B, Hong S, Rajbhandari R, Twitty G, Gray G, Yu H, Benveniste E, Nozell S
    PLoS ONE, 2013;8(11):e78728.
    Species: Human
    Sample Types: Whole Cells
    Applications: cell culture
  302. Comparison of drug and cell-based delivery: engineered adult mesenchymal stem cells expressing soluble tumor necrosis factor receptor II prevent arthritis in mouse and rat animal models.
    Authors: Liu L, Wang G, Hendricks K, Lee K, Bohnlein E, Junker U, Mosca J
    Stem Cells Transl Med, 2013;2(5):362-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  303. Protein carbamylation predicts mortality in ESRD.
    Authors: Koeth R, Kalantar-Zadeh K, Wang Z, Fu X, Tang W, Hazen S
    , 2013;0(0):.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA Standard
  304. Integration and regression of implanted engineered human vascular networks during deep wound healing.
    Authors: Hanjaya-Putra D, Shen Y, Wilson A, Fox-Talbot K, Khetan S, Burdick J, Steenbergen C, Gerecht S
    Stem Cells Transl Med, 2013;2(4):297-306.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  305. The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography.
    Authors: Melo, Rossana, Paganoti, Guillher, Dvorak, Ann M, Weller, Peter F
    PLoS ONE, 2013;8(3):e59578.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  306. Role and regulation of PDGFRalpha signaling in liver development and regeneration.
    Authors: Awuah P, Nejak-Bowen K, Monga S
    Am J Pathol, 2013;182(5):1648-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  307. A20/TNFAIP3 inhibits NF-kappaB activation induced by the Kaposi's sarcoma-associated herpesvirus vFLIP oncoprotein.
    Authors: Sakakibara S, Espigol-Frigole G, Gasperini P, Uldrick T, Yarchoan R, Tosato G
    Oncogene, 2013;32(10):1223-32.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  308. Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays.
    Authors: Todd J, Simpson P, Estis J, Torres V, Wub A
    Cytokine, 2013;64(3):660-5.
    Species: Human
    Sample Types: Plasma
    Applications: ELISA Standard
  309. TCR-driven transendothelial migration of human effector memory CD4 T cells involves Vav, Rac, and myosin IIA.
    Authors: Manes, Thomas D, Pober, Jordan S
    J Immunol, 2013;190(7):3079-88.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  310. IFN-alpha induces APOBEC3G, F, and A in immature dendritic cells and limits HIV-1 spread to CD4+ T cells.
    Authors: Mohanram V, Skold A, Bachle S, Pathak S, Spetz A
    J Immunol, 2013;190(7):3346-53.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  311. A Lectin-EGF antibody promotes regulatory T cells and attenuates nephrotoxic nephritis via DC-SIGN on dendritic cells.
    Authors: Cai, Minchao, Wu, Jing, Mao, Chaoming, Ren, Jianmin, Li, Pu, Li, Xiao, Zhong, Jiuchang, Xu, Chundi, Zhou, Tong
    J Transl Med, 2013;11(0):103.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  312. Interferon-beta induces distinct gene expression response patterns in human monocytes versus T cells.
    Authors: Henig N, Avidan N, Mandel I, Staun-Ram E, Ginzburg E, Paperna T, Pinter R, Miller A
    PLoS ONE, 2013;8(4):e62366.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Attenuated TGF-beta1 responsiveness of dendritic cells and their precursors in atopic dermatitis.
    Authors: Peng W, Maintz L, Allam J, Novak N
    Eur J Immunol, 2013;43(5):1374-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation.
    Authors: Johnston A, Fritz Y, Dawes S, Diaconu D, Al-Attar P, Guzman A, Chen C, Fu W, Gudjonsson J, McCormick T, Ward N
    J Immunol, 2013;190(5):2252-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  315. A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.
    Authors: Llop-Guevara A, Chu D, Walker T, Goncharova S, Fattouh R, Silver J, Moore C, Xie J, O'Byrne P, Coyle A, Kolbeck R, Humbles A, Stampfli M, Jordana M
    PLoS ONE, 2013;9(2):e88714.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.
    Authors: Boisson B, Laplantine E, Prando C, Giliani S, Israelsson E, Xu Z, Abhyankar A, Israel L, Trevejo-Nunez G, Bogunovic D, Cepika A, MacDuff D, Chrabieh M, Hubeau M, Bajolle F, Debre M, Mazzolari E, Vairo D, Agou F, Virgin H, Bossuyt X, Rambaud C, Facchetti F, Bonnet D, Quartier P, Fournet J, Pascual V, Chaussabel D, Notarangelo L, Puel A, Israel A, Casanova J, Picard C
    Nat Immunol, 2012;13(12):1178-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients.
    Authors: Brusic, Ana, Hainz, Ursula, Wadleigh, Martha, Neuberg, Donna, Su, Mei, Canning, Christin, Deangelo, Daniel J, Stone, Richard, Lee, Jeng-Shi, Mulligan, Richard, Ritz, Jerome, Dranoff, Glenn, Sasada, Tetsuro, Wu, Catherin
    Oncoimmunology, 2012;1(7):1095-1103.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  318. The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase.
    Authors: Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD
    J. Biol. Chem., 2012;287(31):25964-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  319. Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.
    Authors: Hutter, Caroline, Kauer, Max, Simonitsch-Klupp, Ingrid, Jug, Gunhild, Schwentner, Raphaela, Leitner, Judith, Bock, Peter, Steinberger, Peter, Bauer, Wolfgang, Carlesso, Nadia, Minkov, Milen, Gadner, Helmut, Stingl, Georg, Kovar, Heinrich, Kriehuber, Ernst
    Blood, 2012;120(26):5199-208.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Osteoblast-like differentiation of cultured human coronary artery smooth muscle cells by bone morphogenetic protein endothelial cell precursor-derived regulator (BMPER).
    Authors: Satomi-Kobayashi S, Kinugasa M, Kobayashi R, Hatakeyama K, Kurogane Y, Ishida T, Emoto N, Asada Y, Takai Y, Hirata K, Rikitake Y
    J Biol Chem, 2012;287(36):30336-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  321. The SDF-1α/CXCR4 Axis is Required for Proliferation and Maturation of Human Fetal Pancreatic Endocrine Progenitor Cells.
    Authors: Kayali AG, Lopez AD, Hao E, Hinton A, Hayek A, King CC
    PLoS ONE, 2012;7(6):e38721.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  322. Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.
    J. Invest. Dermatol., 2012;132(11):2593-600.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  323. Constitutive expression of inter-alpha-inhibitor (IalphaI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex.
    Authors: Zhang S, He H, Day AJ, Tseng SC
    J. Biol. Chem., 2012;287(15):12433-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  324. Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.
    Authors: Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M
    Eur. J. Immunol., 2012;42(4):936-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  325. AAV2/IL-12 gene delivery into dendritic cells (DC) enhances CTL stimulation above other IL-12 applications: Evidence for IL-12 intracrine activity in DC.
    Authors: You C, Shi M, Liu Y, Cao M, Luo R, Hermonat P
    Oncoimmunology, 2012;1(6):847-855.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  326. Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E-selectin expression in human squamous cell carcinomas.
    J. Invest. Dermatol., 2012;132(11):2642-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  327. Kinome-wide functional genomics screen reveals a novel mechanism of TNFα-induced nuclear accumulation of the HIF-1α transcription factor in cancer cells.
    Authors: Schoolmeesters A, Brown DD, Fedorov Y
    PLoS ONE, 2012;7(2):e31270.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
    Gene Ther, 2012;19(10):1035-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Generation of allo-restricted peptide-specific T cells using RNA-pulsed dendritic cells: A three phase experimental procedure.
    Authors: Wilde S, Geiger C, Milosevic S, Mosetter B, Eichenlaub S, Schendel D
    Oncoimmunology, 2012;1(2):129-140.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Mycobacterium tuberculosis infection and tissue factor expression in macrophages.
    Authors: Kothari H, Rao L, Vankayalapati R, Pendurthi U
    PLoS ONE, 2012;7(9):e45700.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  331. Daily exposure to dust alters innate immunity.
    Authors: Sahlander K, Larsson K, Palmberg L
    PLoS ONE, 2012;7(2):e31646.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  332. Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation.
    Authors: Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, Kinoshita H, Sakamoto K, Nakagawa H, Akanuma M, Yoshida H, Maeda S, Koike K
    Infect Immun, 2012;80(11):3795-803.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
    Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
    PLoS ONE, 2012;7(4):e34965.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  334. Expression and regulation of CCL15 by human airway smooth muscle cells.
    Authors: Joubert P, Lajoie-Kadoch S, Wellemans V, Létuvé S, Tulic MK, Halayko AJ, Hamid Q
    Clin. Exp. Allergy, 2011;42(1):85-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection.
    Authors: Cross SA, Cook DR, Chi AW, Vance PJ, Kolson LL, Wong BJ, Jordan-Sciutto KL, Kolson DL
    J. Immunol., 2011;187(10):5015-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  336. Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis.
    Authors: Carrier Y, Ma HL, Ramon HE, Napierata L, Small C, O'Toole M, Young DA, Fouser LA, Nickerson-Nutter C, Collins M, Dunussi-Joannopoulos K, Medley QG
    J. Invest. Dermatol., 2011;131(12):2428-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission.
    Authors: Beck B, Dorfel D, Lichtenegger FS, Geiger C, Lindner L, Merk M, Schendel DJ, Subklewe M
    J Transl Med, 2011;9(0):151.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  338. IL-17A and TNF-alpha Exert Synergistic Effects on Expression of CXCL5 by Alveolar Type II Cells In Vivo and In Vitro.
    Authors: Liu Y, Mei J, Gonzales L, Yang G, Dai N, Wang P, Zhang P, Favara M, Malcolm KC, Guttentag S, Worthen GS
    J. Immunol., 2011;186(5):3197-205.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  339. LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism.
    Authors: Tiller G, Laumen H, Fischer-Posovszky P, Finck A, Skurk T, Keuper M, Brinkmann U, Wabitsch M, Link D, Hauner H
    Int J Obes (Lond), 2011;35(2):208-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  340. HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies.
    Authors: Peressin M, Holl V, Schmidt S, Decoville T, Mirisky D, Lederle A, Delaporte M, Xu K, Aubertin AM, Moog C
    J. Virol., 2011;85(2):1077-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  341. Cadherin-11 regulates fibroblast inflammation.
    Authors: Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM, Brenner MB
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(20):8402-7.
  342. IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.
    Authors: Ramirez-Carrozzi V, Sambandam A, Luis E
    Nat. Immunol., 2011;12(12):1159-66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  343. T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma.
    Authors: Corrigan CJ, Wang W, Meng Q, Fang C, Wu H, Reay V, Lv Z, Fan Y, An Y, Wang YH, Liu YJ, Lee TH, Ying S
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(4):1579-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  344. BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium.
    Authors: Helbing T, Rothweiler R, Ketterer E, Goetz L, Heinke J, Grundmann S, Duerschmied D, Patterson C, Bode C, Moser M
    Blood, 2011;118(18):5040-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  345. Complement Receptor Mac-1 Is an Adaptor for NB1 (CD177)-mediated PR3-ANCA Neutrophil Activation.
    Authors: Jerke U, Rolle S, Dittmar G, Bayat B, Santoso S, Sporbert A, Luft F, Kettritz R
    J. Biol. Chem., 2011;286(9):7070-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  346. Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo.
    Authors: Shin HS, Xu F, Bagchi A, Herrup E, Wilhelmsen K
    J. Immunol., 2011;186(2):1119-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  347. Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction.
    Authors: Estrada-Gutierrez G, Cappello RE, Mishra N, Romero R, Strauss JF, Walsh SW
    Am. J. Pathol., 2011;178(1):451-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  348. Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency.
    Authors: Sancho-Shimizu V, Perez de Diego R, Lorenzo L, Halwani R, Alangari A, Israelsson E, Fabrega S, Cardon A, Maluenda J, Tatematsu M, Mahvelati F, Herman M, Ciancanelli M, Guo Y, AlSum Z, Alkhamis N, Al-Makadma AS, Ghadiri A, Boucherit S, Plancoulaine S, Picard C, Rozenberg F, Tardieu M, Lebon P, Jouanguy E, Rezaei N, Seya T, Matsumoto M, Chaussabel D, Puel A, Zhang SY, Abel L, Al-Muhsen S, Casanova JL
    J. Clin. Invest., 2011;121(12):4889-902.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  349. IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression.
    Authors: Johnston A, Xing X, Guzman AM, Riblett M, Loyd CM, Ward NL, Wohn C, Prens EP, Wang F, Maier LE, Kang S, Voorhees JJ, Elder JT, Gudjonsson JE
    J. Immunol., 2011;186(4):2613-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  350. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes.
    Authors: Liu F, Chen HY, Huang XR, Chung AC, Zhou L, Fu P, Szalai AJ, Lan HY
    Diabetologia, 2011;54(10):2713-23.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  351. Monocytic microparticles activate endothelial cells in an IL-1{beta}-dependent manner.
    Authors: Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N
    Blood, 2011;118(8):2366-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  352. Focal increases of fetal macrophages in placentas from pregnancies with histological chorioamnionitis: potential role of fibroblast monocyte chemotactic protein-1.
    Authors: Toti P, Arcuri F, Tang Z, Schatz F, Zambrano E, Mor G, Niven-Fairchild T, Abrahams VM, Krikun G, Lockwood CJ, Guller S
    Am. J. Reprod. Immunol., 2011;65(5):470-9.
  353. B7-h3 augments the inflammatory response and is associated with human sepsis.
    Authors: Zhang G, Wang J, Kelly J
    J. Immunol., 2010;185(6):3677-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  354. IFN-gamma generates maturation-arrested dendritic cells that induce T cell hyporesponsiveness independent of Foxp3+ T-regulatory cell generation.
    Authors: Rojas D, Krishnan R,
    Immunol. Lett., 2010;132(1):31-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  355. Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.
    Authors: Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D
    J. Immunol., 2010;185(10):6306-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  356. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients.
    Authors: Heo YJ, Joo YB, Oh HJ, Park MK, Heo YM, Cho ML, Kwok SK, Ju JH, Park KS, Cho SG, Park SH, Kim HY, Min JK
    Immunol. Lett., 2010;127(2):150-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  357. IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.
    Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
    J. Immunol., 2010;184(9):4880-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  358. Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration.
    Authors: Johnson LA, Jackson DG
    Int. Immunol., 2010;22(10):839-49.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  359. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
    Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
    Mucosal Immunol, 2010;3(1):40-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  360. Evidence for altered Wnt signaling in psoriatic skin.
    Authors: Gudjonsson JE, Johnston A, Stoll SW
    J. Invest. Dermatol., 2010;130(7):1849-59.
    Species: Human
    Sample Types: Whole Cells
  361. Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis.
    Authors: Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
    J. Immunol., 2010;184(0):5263-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  362. Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression.
    Authors: Xu H, Wang X, Pahar B
    J. Immunol., 2010;185(12):7340-8.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  363. Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines.
    Authors: Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ
    Invest. Ophthalmol. Vis. Sci., 2009;50(6):2702-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  364. The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion.
    Authors: Kato N, Yuzawa Y, Kosugi T
    J. Am. Soc. Nephrol., 2009;20(7):1565-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  365. Soluble decoy receptor 3 modulates the survival and formation of osteoclasts from multiple myeloma bone disease patients.
    Authors: Colucci S, Brunetti G, Mori G, Oranger A, Centonze M, Mori C, Cantatore FP, Tamma R, Rizzi R, Liso V, Zallone A, Grano M
    Leukemia, 2009;23(11):2139-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  366. Ectopic expression of interleukin-1 receptor type II enhances cell migration through activation of the pre-interleukin 1alpha pathway.
    Authors: Chang SY, Su PF, Lee TC
    Cytokine, 2009;45(1):32-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  367. Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
    Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT
    Clin. Immunol., 2009;133(1):27-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  368. Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
    Authors: Dave SH, Tilstra JS, Matsuoka K, Li F, DeMarco RA, Beer-Stolz D, Sepulveda AR, Fink MP, Lotze MT, Plevy SE
    J. Leukoc. Biol., 2009;86(3):633-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  369. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
    Authors: Hao Q, Wang L, Tang H
    Am. J. Physiol., Cell Physiol., 2009;296(4):C821-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  370. Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells.
    Authors: Hirosako S, Goto E, Fujii K, Tsumori K, Hirata N, Tsumura S, Kamohara H, Kohrogi H
    Clin. Exp. Immunol., 2009;155(2):266-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  371. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis.
    Authors: Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P
    Circ. Res., 2009;104(1):60-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  372. Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases.
    Authors: Margulis A, Nocka KH, Brennan AM, Deng B, Fleming M, Goldman SJ, Kasaian MT
    J. Immunol., 2009;183(3):1739-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  373. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis.
    Authors: Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, Kunz S, Docke WD, Asadullah K, Volk HD, Sterry W, Sabat R
    Eur. J. Immunol., 2009;39(12):3570-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  374. TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses.
    Authors: Duraisingham SS, Hornig J, Gotch F, Patterson S
    J. Immunol., 2009;183(4):2242-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  375. Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease.
    Authors: Miller M, Cho JY, Pham A, Ramsdell J, Broide DH
    J. Immunol., 2009;182(1):684-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  376. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.
    Authors: Amiable N, Tat SK, Lajeunesse D, Duval N, Pelletier JP, Martel-Pelletier J, Boileau C
    Bone, 2009;44(6):1143-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  377. Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis.
    Authors: Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, Ohba M, Sueki H, Kokubu F, Hizawa N, Adachi M, Huang SK, Iijima M
    J. Invest. Dermatol., 2009;129(3):650-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Inhibition of double-stranded RNA-induced TSLP in human keratinocytes by glucocorticoids.
    Authors: Le TA, Takai T, Kinoshita H, Suto H, Ikeda S, Okumura K, Ogawa H
    Allergy, 2009;64(8):1231-2.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment.
    Authors: Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pita O, Girolomoni G, Sozzani S
    J. Exp. Med., 2009;206(1):249-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  380. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
    Authors: Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
    J. Allergy Clin. Immunol., 2009;123(1):179-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  381. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.
    Authors: Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F
    Nat. Immunol., 2009;10(8):857-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  382. Nitric oxide attenuates vascular endothelial cadherin-mediated vascular integrity in human chronic inflammation.
    Authors: Hama S, Takeichi O, Fujisaki K, Tanabe N, Maeno M, Ochiai K
    Clin. Exp. Immunol., 2008;154(3):384-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  383. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps.
    Authors: Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP
    J. Allergy Clin. Immunol., 2008;121(6):1385-92, 1392.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  384. Development and validation of sandwich ELISA microarrays with minimal assay interference.
    Authors: Gonzalez RM, Seurynck-Servoss SL, Crowley SA
    J. Proteome Res., 2008;7(6):2406-14.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  385. Effect of fudosteine on mucin production.
    Authors: Rhee CK, Kang CM, You MB, Yoon HK, Kim YK, Kim KH, Moon HS, Park SH, Song JS
    Eur. Respir. J., 2008;32(5):1195-202.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  386. Epidermal receptor activator of NF-kappaB ligand controls Langerhans cells numbers and proliferation.
    Authors: Barbaroux JB, Beleut M, Brisken C, Mueller CG, Groves RW
    J. Immunol., 2008;181(2):1103-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  387. Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis.
    Authors: Stanczyk J, Pedrioli DM, Brentano F, Sanchez-Pernaute O, Kolling C, Gay RE, Detmar M, Gay S, Kyburz D
    Arthritis Rheum., 2008;58(4):1001-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  388. Expression and regulation of CCR1 by airway smooth muscle cells in asthma.
    Authors: Joubert P, Lajoie-Kadoch S, Welman M, Dragon S, Letuvee S, Tolloczko B, Halayko AJ, Gounni AS, Maghni K, Hamid Q
    J. Immunol., 2008;180(2):1268-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  389. p38 mitogen-activated protein kinase inhibitor LY2228820 enhances bortezomib-induced cytotoxicity and inhibits osteoclastogenesis in multiple myeloma; therapeutic implications.
    Authors: Ishitsuka K, Hideshima T, Neri P, Vallet S, Shiraishi N, Okawa Y, Shen Z, Raje N, Kiziltepe T, Ocio EM, Chauhan D, Tassone P, Munshi N, Campbell RM, Dios AD, Shih C, Starling JJ, Tamura K, Anderson KC
    Br. J. Haematol., 2008;141(5):598-606.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  390. A novel method to establish microglia-free astrocyte cultures: comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia.
    Authors: Crocker SJ, Frausto RF, Whitton JL, Milner R
    Glia, 2008;56(0):1187-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  391. IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation.
    Authors: Jasny E, Eisenblatter M, Matz-Rensing K, Tenner-Racz K, Tenbusch M, Schrod A, Stahl-Hennig C, Moos V, Schneider T, Racz P, Uberla K, Kaup FJ, Ignatius R
    J. Immunol., 2008;180(10):6629-39.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  392. Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes.
    Authors: Wolk K, Witte K, Witte E, Proesch S, Schulze-Tanzil G, Nasilowska K, Thilo J, Asadullah K, Sterry W, Volk HD, Sabat R
    J. Leukoc. Biol., 2008;83(5):1181-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  393. Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma.
    Authors: Wente MN, Gaida MM, Mayer C, Michalski CW, Haag N, Giese T, Felix K, Bergmann F, Giese NA, Friess H
    Int. J. Oncol., 2008;33(2):297-308.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  394. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo.
    Authors: Biancotto A, Iglehart SJ, Lisco A, Vanpouille C, Grivel JC, Lurain NS, Reichelderfer PS, Margolis LB
    AIDS Res. Hum. Retroviruses, 2008;24(3):453-62.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  395. Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells.
    Authors: Secchiero P, Melloni E, Corallini F, Beltrami AP, Alviano F, Milani D, D'Aurizio F, di Iasio MG, Cesselli D, Bagnara GP, Zauli G
    Stem Cells, 2008;26(11):2955-63.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  396. Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts.
    Authors: Kwan Tat S, Pelletier JP, Amiable N, Boileau C, Lajeunesse D, Duval N, Martel-Pelletier J
    Arthritis Rheum., 2008;58(12):3820-30.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  397. IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells.
    Authors: Gerber SA, Pober JS
    J. Immunol., 2008;181(2):1052-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  398. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils.
    Authors: Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H
    J. Allergy Clin. Immunol., 2008;121(6):1484-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  399. Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells.
    Authors: Lee SK, Pi SH, Kim SH, Min KS, Lee HJ, Chang HS, Kang KH, Kim HR, Shin HI, Lee SK, Kim EC
    Clin. Exp. Immunol., 2007;150(3):567-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  400. IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease.
    Authors: Wolk K, Witte E, Hoffmann U, Doecke WD, Endesfelder S, Asadullah K, Sterry W, Volk HD, Wittig BM, Sabat R
    J. Immunol., 2007;178(9):5973-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  401. Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression.
    Authors: Kamohara H, Ogawa M, Ishiko T, Sakamoto K, Baba H
    Int. J. Oncol., 2007;30(4):977-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  402. Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression.
    Authors: Brechter AB, Lerner UH
    Arthritis Rheum., 2007;56(3):910-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  403. IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation.
    Authors: Dame TM, Orenzoff BL, Palmer LE, Furie MB
    J. Immunol., 2007;178(2):1172-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  404. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.
    Authors: Ponte AL, Marais E, Gallay N, Langonne A, Delorme B, Herault O, Charbord P, Domenech J
    Stem Cells, 2007;25(7):1737-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  405. Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
    Authors: Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS
    J. Biol. Chem., 2007;282(43):31643-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  406. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells.
    Authors: Tacke F, Gabele E, Bataille F, Schwabe RF, Hellerbrand C, Klebl F, Straub RH, Luedde T, Manns MP, Trautwein C, Brenner DA, Scholmerich J, Schnabl B
    Dig. Dis. Sci., 2007;52(12):3404-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  407. Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis.
    Authors: Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C
    J. Leukoc. Biol., 2007;82(4):946-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  408. The F11 receptor (F11R/JAM-A) in atherothrombosis: overexpression of F11R in atherosclerotic plaques.
    Authors: Babinska A, Azari BM, Salifu MO, Liu R, Jiang XC, Sobocka MB, Boo D, Al Khoury G, Deitch JS, Marmur JD, Ehrlich YH, Kornecki E
    Thromb. Haemost., 2007;97(2):272-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  409. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
    Authors: Sa SM, Valdez PA, Wu J
    J. Immunol., 2007;178(4):2229-40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  410. SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration.
    Authors: Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R
    J. Leukoc. Biol., 2007;81(3):748-56.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  411. Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes.
    Authors: Hundhausen C, Schulte A, Schulz B, Andrzejewski MG, Schwarz N, von Hundelshausen P, Winter U, Paliga K, Reiss K, Saftig P, Weber C, Ludwig A
    J. Immunol., 2007;178(12):8064-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  412. Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators.
    Authors: Orfanos SE, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, Sotiropoulou C, Zakynthinos S, Armaganidis A, Papapetropoulos A, Roussos C
    Crit. Care Med., 2007;35(1):199-206.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  413. Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers.
    Authors: van Grevenstein WM, Hofland LJ, van Rossen ME, van Koetsveld PM, Jeekel J, van Eijck CH
    Dig. Dis. Sci., 2007;52(10):2775-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  414. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
    Authors: Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, Repici A, Arena V, Malesci A, Panes J, Grinnell BW, Danese S
    J. Clin. Invest., 2007;117(7):1951-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  415. The role of vascular cell adhesion molecule 1/ very late activation antigen 4 in endothelial progenitor cell recruitment to rheumatoid arthritis synovium.
    Authors: Silverman MD, Haas CS, Rad AM, Arbab AS, Koch AE
    Arthritis Rheum., 2007;56(6):1817-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  416. Role of mesothelial cell-derived granulocyte colony-stimulating factor in interleukin-17-induced neutrophil accumulation in the peritoneum.
    Authors: Witowski J, Ksiazek K, Warnecke C, Kuzlan M, Korybalska K, Tayama H, Wisniewska-Elnur J, Pawlaczyk K, Trominska J, Breborowicz A, Jorres A
    Kidney Int., 2007;71(6):514-25.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  417. Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques.
    Authors: Zahorchak AF, Kean LS, Tokita D, Turnquist HR, Abe M, Finke J, Hamby K, Rigby MR, Larsen CP, Thomson AW
    Transplantation, 2007;84(2):196-206.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  418. Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway.
    Authors: Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2007;210(1):192-200.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  419. Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.
    Authors: Dambacher J, Beigel F, Seiderer J, Haller D, Goke B, Auernhammer CJ, Brand S
    Gut, 2007;56(9):1257-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  420. Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm.
    Authors: Schreiber TH, Shinder V, Cain DW, Alon R, Sackstein R
    Blood, 2007;109(4):1381-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  421. Calcineurin modulates the catabolic and anabolic activity of chondrocytes and participates in the progression of experimental osteoarthritis.
    Authors: Yoo SA, Park BH, Yoon HJ, Lee JY, Song JH, Kim HA, Cho CS, Kim WU
    Arthritis Rheum., 2007;56(7):2299-311.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  422. CD28-mediated regulation of multiple myeloma cell proliferation and survival.
    Authors: Bahlis NJ, King AM, Kolonias D, Carlson LM, Liu HY, Hussein MA, Terebelo HR, Byrne GE, Levine BL, Boise LH, Lee KP
    Blood, 2007;109(11):5002-10.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  423. Regulation of neuronal pituitary adenylate cyclase-activating polypeptide expression during culture of guinea-pig cardiac ganglia.
    Authors: Girard BM, Young BA, Buttolph TR, White SL, Parsons RL
    Neuroscience, 2007;146(2):584-93.
    Species: Guinea Pig
    Sample Types: Whole Cells
    Applications: Bioassay
  424. Ultrasensitive flow-based immunoassays using single-molecule counting.
    Authors: Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
    Clin. Chem., 2007;53(11):1990-5.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  425. Guinea pig neutrophils infected with Mycobacterium tuberculosis produce cytokines which activate alveolar macrophages in noncontact cultures.
    Authors: Sawant KV, McMurray DN
    Infect. Immun., 2007;75(4):1870-7.
  426. Pharmacologic inhibition of tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood.
    Authors: Hall JP, Kurdi Y, Hsu S, Cuozzo J, Liu J, Telliez JB, Seidl KJ, Winkler A, Hu Y, Green N, Askew GR, Tam S, Clark JD, Lin LL
    J. Biol. Chem., 2007;282(46):33295-304.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  427. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines.
    Authors: Qui H, Ferrell EP, Nolan N, Phelps BH, Tabibiazar R, Whitney DH, Naelfski EA
    Clin. Chem., 2007;53(11):2010-2.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  428. Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells.
    Authors: Fitzgerald DC, Meade KG, McEvoy AN, Lillis L, Murphy EP, Machugh DE, Baird AW
    Vet. Immunol. Immunopathol., 2007;116(1):59-68.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  429. Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork.
    Authors: Kelley MJ, Rose AY, Song K, Chen Y, Bradley JM, Rookhuizen D, Acott TS
    Invest. Ophthalmol. Vis. Sci., 2007;48(6):2634-43.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  430. Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells.
    Authors: Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di Iasio MG, Rustighi A, Del Sal G, Zauli G
    Blood, 2007;111(3):1287-94.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  431. IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis.
    Authors: Caruso R, Fina D, Peluso I, Fantini MC, Tosti C, Del Vecchio Blanco G, Paoluzi OA, Caprioli F, Andrei F, Stolfi C, Romano M, Ricci V, MacDonald TT, Pallone F, Monteleone G
    J. Immunol., 2007;178(9):5957-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  432. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates.
    Authors: Luty WH, Rodeberg D, Parness J, Vyas YM
    J. Immunol., 2007;179(2):819-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  433. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
    Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
    Blood, 2007;111(8):4096-105.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  434. Mitochondrially targeted ceramide LCL-30 inhibits colorectal cancer in mice.
    Authors: Dahm F, Bielawska A, Nocito A, Georgiev P, Szulc ZM, Bielawski J, Jochum W, Dindo D, Hannun YA, Clavien PA
    Br. J. Cancer, 2007;98(1):98-105.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  435. TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells.
    Authors: Kato A, Favoreto S, Avila PC, Schleimer RP
    J. Immunol., 2007;179(2):1080-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  436. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.
    Authors: Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P
    AIDS, 2007;21(10):1263-72.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  437. Dehydroepiandrosterone inhibits the TNF-alpha-induced inflammatory response in human umbilical vein endothelial cells.
    Authors: Gutierrez G, Mendoza C, Zapata E, Montiel A, Reyes E, Montano LF, Lopez-Marure R
    Atherosclerosis, 2007;190(1):90-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  438. Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1.
    Authors: Lee SY, Cherla RP, Tesh VL
    Infect. Immun., 2007;75(3):1291-302.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  439. Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells.
    Authors: Pietila TE, Veckman V, Lehtonen A, Lin R, Hiscott J, Julkunen I
    J. Immunol., 2007;178(1):253-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  440. IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune response.
    Authors: Rao DA, Tracey KJ, Pober JS
    J. Immunol., 2007;179(10):6536-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  441. LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes.
    Authors: Kang YM, Kim SY, Kang JH
    Arthritis Rheum., 2007;56(4):1106-17.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  442. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
    Authors: Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM
    Blood, 2007;109(10):4272-9.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  443. Constitutive and inducible thymic stromal lymphopoietin expression in human airway smooth muscle cells: role in chronic obstructive pulmonary disease.
    Authors: Zhang K, Shan L, Rahman MS, Unruh H, Halayko AJ, Gounni AS
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(2):L375-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  444. Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection.
    Authors: Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, Szymkowski DE
    J. Immunol., 2007;179(3):1872-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  445. Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis.
    Authors: Wosik K, Cayrol R, Dodelet-Devillers A, Berthelet F, Bernard M, Moumdjian R, Bouthillier A, Reudelhuber TL, Prat A
    J. Neurosci., 2007;27(34):9032-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  446. Modeling of tumor necrosis factor receptor superfamily 1A mutants associated with tumor necrosis factor receptor-associated periodic syndrome indicates misfolding consistent with abnormal function.
    Authors: Rebelo SL, Bainbridge SE, Amel-Kashipaz MR, Radford PM, Powell RJ, Todd I, Tighe PJ
    Arthritis Rheum., 2006;54(8):2674-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  447. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
    Authors: Ebert EC, Mehta V
    Cell. Immunol., 2006;241(1):7-13.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  448. IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts.
    Authors: Létuvé S, Lajoie-Kadoch S, Audusseau S, Rothenberg ME, Fiset PO, Ludwig MS, Hamid Q
    J. Allergy Clin. Immunol., 2006;117(3):590-6.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  449. Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation.
    Authors: Nguyen AN, Stebbins EG, Henson M, O&amp;amp;apos;Young G, Choi SJ, Quon D, Damm D, Reddy M, Ma JY, Haghnazari E, Kapoun AM, Medicherla S, Protter A, Schreiner GF, Kurihara N, Anderson J, Roodman GD, Navas TA, Higgins LS
    Exp. Cell Res., 2006;312(10):1909-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  450. Expression of B7-H1 on gastric epithelial cells: its potential role in regulating T cells during Helicobacter pylori infection.
    Authors: Das S, Suarez G, Beswick EJ, Sierra JC, Graham DY, Reyes VE
    J. Immunol., 2006;176(5):3000-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  451. The ascochlorin derivative, AS-6, inhibits TNF-alpha-induced adhesion molecule and chemokine expression in rat vascular smooth muscle cells.
    Authors: Park KG, Lee KM, Magae J, Kim YN, Lee KU, Lee IK
    Life Sci., 2006;80(2):120-6.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  452. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.
    Authors: Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS
    Bone, 2006;38(4):497-508.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  453. Sepsis and pathophysiology of anthrax in a nonhuman primate model.
    Authors: Stearns-Kurosawa DJ, Lupu F, Taylor FB, Kinasewitz G, Kurosawa S
    Am. J. Pathol., 2006;169(2):433-44.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  454. Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression.
    Authors: Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L
    J. Endocrinol., 2006;191(1):65-81.
    Species: Hamster
    Sample Types: Whole Cells
    Applications: Bioassay
  455. Increased ENA-78 in the follicular fluid of patients with endometriosis.
    Authors: Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA
    Acta Obstet Gynecol Scand, 2006;85(3):336-42.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  456. Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli.
    Authors: Baginski TK, Dabbagh K, Satjawatcharaphong C, Swinney DC
    Am. J. Respir. Cell Mol. Biol., 2006;35(2):165-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  457. Dendritic cells can turn CD4+ T lymphocytes into vascular endothelial growth factor-carrying cells by intercellular neuropilin-1 transfer.
    Authors: Bourbie-Vaudaine S, Blanchard N, Hivroz C, Romeo PH
    J. Immunol., 2006;177(3):1460-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  458. Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha.
    Authors: Daryadel A, Grifone RF, Simon HU, Yousefi S
    J. Biol. Chem., 2006;281(37):27653-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  459. Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21.
    Authors: Monteleone G, Caruso R, Fina D, Peluso I, Gioia V, Stolfi C, Fantini MC, Caprioli F, Tersigni R, Alessandroni L, MacDonald TT, Pallone F
    Gut, 2006;55(12):1774-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  460. Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis.
    Authors: Wan B, Nie H, Liu A, Feng G, He D, Xu R, Zhang Q, Dong C, Zhang JZ
    J. Immunol., 2006;177(12):8844-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  461. Selective regulation of IL-10 signaling and function by zymosan.
    Authors: Du Z, Kelly E, Mecklenbrauker I, Agle L, Herrero C, Paik P, Ivashkiv LB
    J. Immunol., 2006;176(8):4785-92.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  462. Differential survival of leukocyte subsets mediated by synovial, bone marrow, and skin fibroblasts: site-specific versus activation-dependent survival of T cells and neutrophils.
    Authors: Filer A, Parsonage G, Smith E, Osborne C, Thomas AM, Curnow SJ, Rainger GE, Raza K, Nash GB, Lord J, Salmon M, Buckley CD
    Arthritis Rheum., 2006;54(7):2096-108.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  463. Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia.
    Authors: Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA
    Exp. Hematol., 2006;34(10):1312-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  464. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression.
    Authors: Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH
    Mol. Cell. Biol., 2006;26(8):3071-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  465. Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
    Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
    J. Immunol., 2006;177(11):7665-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  466. Intraarticular corticosteroids decrease synovial RANKL expression in inflammatory arthritis.
    Authors: Makrygiannakis D, af Klint E, Catrina SB, Botusan IR, Klareskog E, Klareskog L, Ulfgren AK, Catrina AI
    Arthritis Rheum., 2006;54(5):1463-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  467. Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
    Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
    J. Immunol., 2006;176(6):3742-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  468. LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis.
    Authors: Edwards JR, Sun SG, Locklin R, Shipman CM, Adamopoulos IE, Athanasou NA, Sabokbar A
    Arthritis Rheum., 2006;54(5):1451-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  469. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis.
    Authors: Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, Biswal S
    J. Clin. Invest., 2006;116(4):984-95.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  470. Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).
    Authors: Hanabuchi S, Watanabe N, Wang YH, Ito T, Shaw J, Cao W, Qin FX, Liu YJ
    Blood, 2006;107(9):3617-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  471. Spatial compartmentalization of tumor necrosis factor (TNF) receptor 1-dependent signaling pathways in human airway smooth muscle cells. Lipid rafts are essential for TNF-alpha-mediated activation of RhoA but dispensable for the activation of the NF-kappaB and MAPK pathways.
    Authors: Hunter I, Nixon GF
    J. Biol. Chem., 2006;281(45):34705-15.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  472. HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
    Authors: Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J
    Glia, 2006;54(6):619-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  473. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
    Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
    J. Exp. Med., 2006;203(12):2763-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  474. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist.
    Authors: Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME
    J. Virol., 2005;79(20):12828-39.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Types: Whole Cells
    Applications: Bioassay
  475. Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism.
    Authors: Vasir B, Avigan D, Wu Z, Crawford K, Turnquist S, Ren J, Kufe D
    J. Immunol., 2005;174(4):2376-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  476. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
    Authors: Vergne-Salle&lt;/LastName&gt;&lt;F P&lt;/Initial, Vergne-Salle P, Leger DY, Bertin P, Treves R, Beneytout JL, Liagre B
    Cytokine, 2005;31(5):335-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  477. Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K.
    Authors: Mandelin J, Li TF, Hukkanen M, Liljestrom M, Salo J, Santavirta S, Konttinen YT
    J. Rheumatol., 2005;32(4):713-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  478. CC chemokines and transmigration of eosinophils in the presence of vascular cell adhesion molecule 1.
    Authors: Yamamoto H, Nagata M, Sakamoto Y
    Ann. Allergy Asthma Immunol., 2005;94(2):292-300.
    Species: Human
    Sample Types: Cell Culture Supernates
    Applications: Bioassay
  479. Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis.
    Authors: Iversen PO, Wiig H
    Clin. Cancer Res., 2005;11(19):6793-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  480. Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle.
    Authors: Ameredes BT, Calhoun WJ
    J. Allergy Clin. Immunol., 2005;116(1):65-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  481. Generation of feline dendritic cells derived from peripheral blood monocytes for in vivo use.
    Authors: Freer G, Matteucci D, Mazzetti P, Bozzacco L, Bendinelli M
    Clin. Diagn. Lab. Immunol., 2005;12(10):1202-8.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Bioassay
  482. TNFalpha increases the inflammatory response to vascular balloon injury without accelerating neointimal formation.
    Authors: Miller AM, McPhaden AR, Preston A, Wadsworth RM, Wainwright CL
    Atherosclerosis, 2005;179(1):51-9.
    Species: Rabbit
    Sample Types: Whole Cells
    Applications: Bioassay
  483. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt.
    Authors: Morel J, Audo R, Hahne M, Combe B
    J. Biol. Chem., 2005;280(16):15709-18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  484. Phagocytosis of codeveloping megakaryocytic progenitors by dendritic cells in culture with thrombopoietin and tumor necrosis factor-alpha and its possible role in hemophagocytic syndrome.
    Authors: Saito K, Hirokawa M, Inaba K, Fukaya H, Kawabata Y, Komatsuda A, Yamashita J, Sawada K
    Blood, 2005;107(4):1366-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  485. Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes.
    Authors: Mortara L, Ploquin MJ, Faye A, Scott-Algara D, Vaslin B, Butor C, Hosmalin A, Barre-Sinoussi F, Diop OM, Muller-Trutwin MC
    J. Immunol. Methods, 2005;308(1):138-55.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Types: Whole Cells
    Applications: Bioassay
  486. Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties.
    Authors: Satchell SC, Anderson KL, Mathieson PW
    J. Am. Soc. Nephrol., 2004;15(3):566-74.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  487. KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation.
    Authors: SenBanerjee S, Lin Z, Atkins GB, Greif DM, Rao RM, Kumar A, Feinberg MW, Chen Z, Simon DI, Luscinskas FW, Michel TM, Gimbrone MA, Garcia-Cardena G, Jain MK
    J. Exp. Med., 2004;199(10):1305-15.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  488. The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells.
    Authors: Sade H, Krishna S, Sarin A
    J. Biol. Chem., 2004;279(4):2937-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  489. Human bronchial epithelial cells express and secrete MMP-12.
    Authors: Lavigne MC, Thakker P, Gunn J, Miyashiro JS, Wasserman AM, Wei SQ, Pelker JW
    Biochem. Biophys. Res. Commun., 2004;324(2):534-46.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  490. CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure.
    Authors: Pivarcsi A, Gombert M, Dieu-Nosjean MC, Kubitza R, Meller S, Rieker J, Muller A, Da Cunha L, Haahtela A, Sonkoly E, Fridman WH, Alenius H, Kemeny L, Ruzicka T, Zlotnik A
    J. Immunol., 2004;173(9):5810-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  491. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
    Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
    J. Immunol., 2004;173(5):3482-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  492. Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1).
    Authors: Chopin V, Slomianny C, Hondermarck H, Le Bourhis X
    Exp. Cell Res., 2004;298(2):560-73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  493. Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
    Authors: Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
    Immunology, 2004;112(2):274-89.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  494. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
    Authors: Copeland S, Siddiqui J, Remick D
    J. Immunol. Methods, 2004;284(1):99-106.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  495. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs.
    Authors: Ferlazzo G, Pack M, Thomas D, Paludan C, Schmid D, Strowig T, Bougras G, Muller WA, Moretta L, Munz C
    Proc. Natl. Acad. Sci. U.S.A., 2004;101(47):16606-11.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  496. Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
    Authors: Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM
    Biochem. J., 2004;380(0):425-33.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  497. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004;200(11):1419-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  498. Impact of fibronectin fragments on the transendothelial migration of HIV-infected leukocytes and the development of subendothelial foci of infectious leukocytes.
    Authors: Birdsall HH, Porter WJ, Green DM, Rubio J, Trial J, Rossen RD
    J. Immunol., 2004;173(4):2746-54.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  499. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis.
    Authors: Phillips TM
    Electrophoresis, 2004;25(10):1652-9.
    Species: N/A
    Sample Types: N/A
    Applications: Standard
  500. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004;200(11):1419-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  501. Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes.
    Authors: Johansson MW, Lye MH, Barthel SR, Duffy AK, Annis DS, Mosher DF
    Am. J. Respir. Cell Mol. Biol., 2004;31(4):413-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  502. Activation of primary porcine endothelial cells induces release of porcine endogenous retroviruses.
    Authors: Cunningham DA, Dos Santos Cruz GJ, Fernandez-Suarez XM, Whittam AJ, Herring C, Copeman L, Richards A, Langford GA
    Transplantation, 2004;77(7):1071-9.
    Species: Porcine
    Sample Types: Whole Cells
    Applications: Bioassay
  503. CD14 is an acute-phase protein.
    Authors: Bas S, Gauthier BR, Spenato U, Stingelin S, Gabay C
    J. Immunol., 2004;172(7):4470-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  504. TARC augments TNF-alpha-induced CTACK production in keratinocytes.
    Authors: Vestergaard C, Johansen C, Christensen U, Just H, Hohwy T, Deleuran M
    Exp. Dermatol., 2004;13(9):551-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  505. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
    Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
    Blood, 2004;104(2):314-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  506. TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia.
    Authors: Ryan LA, Peng H, Erichsen DA, Huang Y, Persidsky Y, Zhou Y, Gendelman HE, Zheng J
    J. Neuroimmunol., 2004;148(1):127-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  507. The effect of inflammatory cytokines on secretion of macrophage colony-stimulating factor and monocyte chemoattractant protein-1 in human granulosa cells.
    Authors: Kawano Y, Fukuda J, Itoh H, Takai N, Nasu K, Miyakawa I
    Am. J. Reprod. Immunol., 2004;52(2):124-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  508. trans fatty acids and systemic inflammation in heart failure.
    Authors: Mozaffarian D, Rimm EB, King IB, Lawler RL, McDonald GB, Levy WC
    Am. J. Clin. Nutr., 2004;80(6):1521-5.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA Standard
  509. Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta.
    Authors: Park JS, Kim YS, Jee YK, Myong NH, Lee KY
    Scand. J. Immunol., 2003;57(5):463-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  510. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis.
    Authors: Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T
    Proc. Natl. Acad. Sci. U.S.A., 2003;100(16):9452-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  511. CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin.
    Authors: Cardones AR, Murakami T, Hwang ST
    Cancer Res., 2003;63(20):6751-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  512. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
    Authors: McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N
    J. Clin. Invest., 2003;112(4):598-607.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  513. LIGHT, a member of the tumor necrosis factor ligand superfamily, prevents tumor necrosis factor-alpha-mediated human primary hepatocyte apoptosis, but not Fas-mediated apoptosis.
    Authors: Hikichi Y, Tsuji I, Shintani Y
    J. Biol. Chem., 2002;277(51):50054-61.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  514. Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus.
    Authors: Favre D, Blouin V, Provost N, Spisek R, Porrot F, Bohl D, Marme F, Cherel Y, Salvetti A, Hurtrel B, Heard JM, Riviere Y, Moullier P
    J. Virol., 2002;76(22):11605-11.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  515. Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells.
    Authors: Messmer D, Jacque JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M
    J. Immunol., 2002;169(8):4172-82.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  516. Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications.
    Authors: Mitsiades CS, Mitsiades N, Poulaki V, Schlossman R, Akiyama M, Chauhan D, Hideshima T, Treon SP, Munshi NC, Richardson PG, Anderson KC
    Oncogene, 2002;21(37):5673-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  517. Acute topical application of tumor necrosis factor alpha evokes protein kinase A-dependent responses in rat sensory neurons.
    Authors: Zhang JM, Li H, Liu B, Brull SJ
    J. Neurophysiol., 2002;88(3):1387-92.
    Species: Rat
    Sample Types: In Vivo
    Applications: In Vivo
  518. The correlation of adhesions and peritoneal fluid cytokine concentrations: a pilot study.
    Authors: Cheong YC, Laird SM, Shelton JB, Ledger WL, Li TC, Cooke ID
    Hum. Reprod., 2002;17(4):1039-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  519. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases.
    Authors: Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, Girolomoni G
    J. Leukoc. Biol., 2001;70(4):617-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  520. Tumour necrosis factor-alpha- and interleukin-1beta-stimulated cell proliferation through activation of mitogen-activated protein kinase in canine tracheal smooth muscle cells.
    Authors: Yang CM, Luo SF, Wang CC, Chiu CT, Chien CS, Lin CC, Hsiao LD
    Br. J. Pharmacol., 2000;130(4):891-9.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  521. Perfusion-contraction mismatch with coronary microvascular obstruction: role of inflammation.
    Authors: Dorge H, Neumann T, Behrends M, Skyschally A, Schulz R, Kasper C, Erbel R, Heusch G
    Am. J. Physiol. Heart Circ. Physiol., 2000;279(6):H2587-92.
    Species: Canine
    Sample Types: Whole Cells
    Applications: Bioassay
  522. Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver.
    Authors: Barcena A, Park SW, Banapour B, Muench MO, Mechetner E
    Blood, 1996;88(6):2013-25.
    Species: Human
    Sample Types:
    Applications: Bioassay
  523. Natural killer cell-produced IFN-gamma and TNF-alpha induce target cell cytolysis through up-regulation of ICAM-1.
    Authors: Wang R, Jaw JJ, Jaw J, Stutzman N, Stutzman NC, Zou Z, Sun PD
    J Leukoc Biol, 0;91(2):299-309.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  524. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
    Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
    J Biol Chem, 0;284(36):24035-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  525. Interleukin-1 family cytokines and their regulatory proteins in normal pregnancy and pre-eclampsia.
    Authors: Southcombe J, Redman C, Sargent I, Granne I
    Clin Exp Immunol, 0;181(3):480-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay

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Animal-Free Recombinant Proteins

Reviews for Recombinant Human TNF-alpha Protein

Average Rating: 4.8 (Based on 20 Reviews)

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Recombinant Human TNF-alpha Protein
By Anonymous on 09/10/2018
Application: In vitro bioactivity in cell culture
Reason for Rating: Was used to stimulate human aortic endothelial cells.

Recombinant Human TNF-alpha Protein
By Anonymous on 08/06/2018
Application: Immunoassay Standard

Recombinant Human TNF-alpha Protein
By Anonymous on 01/29/2018
Application: Immunoassay Standard

Recombinant Human TNF-alpha Protein
By Anonymous on 01/08/2018
Application: Cell proliferation
Reason for Rating: Works very well to induce NF-KB. Used it in our publications

We tried it for induction of NF-KB detected with luciferase and immunoblot


Recombinant Human TNF-alpha Protein
By Anonymous on 10/30/2017
Application: In vivo study

Recombinant Human TNF-alpha Protein
By Anonymous on 07/17/2017
Application: In vitro bioactivity in cell culture

Recombinant Human TNF-alpha Protein
By Anonymous on 06/01/2017
Application: In vitro bioactivity in cell culture

Recombinant Human TNF-alpha Protein
By Anonymous on 05/23/2017
Application: Cell migration/motility

Recombinant Human TNF-alpha Protein
By Anonymous on 05/16/2017
Application: In vitro bioactivity in cell culture
Reason for Rating: Consistent and expect bioactive in our cell culture assays

We used TNF-a to stimulation macrophages and myofibroblast


Recombinant Human TNF-alpha Protein
By Anonymous on 05/15/2017

Recombinant Human TNF-alpha Protein
By Anonymous on 12/19/2016
Application: In vitro bioactivity in cell culture
Reason for Rating: Functioned well and reproducible data with TNF from another company.

Recombinant Human TNF-alpha Protein
By Anonymous on 08/01/2016
Application: In vitro bioactivity in cell culture

Rat primary embryonic cortical culture stimulated with TNFa (10, 50, 100 ng/ml), PBS+BSA (negative stimulation control), or Okadaic Acid (OA; positive phosphorylation control) for 30 minutes. Protein isolated for western blot analysis of phospho-Akt.


Recombinant Human TNF-alpha Protein
By Anonymous on 07/29/2016
Application: In vitro bioactivity in cell culture

Cultured endothelial cells were pre-treated (or not) with 1mg/mL HDL, then treated for 6 hours with 10ng/mL TNFa. TNFa treatment caused a massive upregulation of ICAM1 and E-Selectin versus control cells (untreated); HDL pre-treatment partially reversed this response.


Recombinant Human TNF-alpha Protein
By Anonymous on 07/21/2016
Application: In vitro bioactivity in cell culture

Recombinant Human TNF-alpha Protein
By Anonymous on 07/21/2016
Application: In vitro bioactivity in cell culture
Reason for Rating: At equal concentrations this protein supplied by R and D systems showed biological activity in our assay system (induction of known downstream genes) when the same protein from two other suppliers failed in all but the positive control condition.

Recombinant Human TNF-alpha Protein
By Anonymous on 05/16/2016
Application: Immunoassay Standard

Recombinant Human TNF-alpha Protein
By Anonymous on 05/12/2016
Application: Our lab has repeatedly purchased this product from 2014 until now. I could say it is excellent. And we will keep use it.

Recombinant Human TNF-alpha Protein
By Anonymous on 02/12/2016
Application: Cell Adhesion
Reason for Rating: This has worked well in WB

Recombinant Human TNF-alpha Protein
By Anonymous on 01/29/2016
Application: Cell Adhesion
Reason for Rating: the band is strong and clear.

Recombinant Human TNF-alpha Protein
By Anonymous on 01/13/2016
Application: use TNF-alpha to stimulate human epithelial cell, the production of inflammation factor is stable and strongly evaluated by western blot and ELISA.
Reason for Rating: stable cheap and convenience