Recombinant Human TNF-alpha Protein

Telomere-to-mitochondria signalling by ZBP1 mediates replicative crisis
Authors: J Nassour, LG Aguiar, A Correia, TT Schmidt, L Mainz, S Przetocka, C Haggblom, N Tadepalle, A Williams, MN Shokhirev, SC Akincilar, V Tergaonkar, GS Shadel, J Karlseder
Nature, 2023-02-08;614(7949):767-773.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TGF-Beta Induces Activin A Production in Dermal Fibroblasts Derived from Patients with Fibrodysplasia Ossificans Progressiva
Authors: RD de Ruiter, LE Wisse, T Schoenmake, M Yaqub, G Sánchez-Du, EMW Eekhoff, D Micha
International Journal of Molecular Sciences, 2023-01-24;24(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fructose-1,6-bisphosphatase 1 dephosphorylates IkappaBalpha and suppresses colorectal tumorigenesis
Authors: W Zhu, H Chu, Y Zhang, T Luo, H Yu, H Zhu, Y Liu, H Gao, Y Zhao, Q Li, X Wang, G Li, W Yang
Cell Research, 2023-01-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-inflammatory properties of antiangiogenic fucoidan in retinal pigment epithelium cells
Authors: P Dörschmann, C Seeba, T Thalenhors, J Roider, A Klettner
Heliyon, 2023;9(4):e15202.
Species: Porcine
Sample Types: Whole Cells
Applications: Cell Culture

NKG2D receptor activation drives primary graft dysfunction severity and poor lung transplantation outcomes
Authors: DR Calabrese, T Tsao, M Magnen, C Valet, Y Gao, B Mallavia, JJ Tian, EA Aminian, KM Wang, A Shemesh, EB Punzalan, A Sarma, CS Calfee, SA Christenso, CR Langelier, SR Hays, JA Golden, LE Leard, ME Kleinhenz, NA Kolaitis, RJ Shah, A Venado, LL Lanier, JR Greenland, DM Sayah, A Ardehali, J Kukreja, SS Weigt, JA Belperio, JP Singer, MR Looney
JCI Insight, 2022-12-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Novel Cortisol Immunosensor Based on a Hafnium Oxide/Silicon Structure for Heart Failure Diagnosis
Authors: H Ben Halima, N Zine, J Bausells, N Jaffrezic-, A Errachid
Micromachines, 2022-12-16;13(12):.
Species: Human
Sample Types: Recombinanat Protein
Applications: Bioassay

Intestinal epithelial BLT1 promotes mucosal repair
Authors: S Hayashi, CK Muraleedha, M Oku, S Tomar, SP Hogan, M Quiros, CA Parkos, A Nusrat
JCI Insight, 2022-12-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Blood serum analysis: A modified sandwich enzyme-linked immunosorbent assay protocol
Authors: D Cai, M Fraunfelde, SY Chen
MethodsX, 2022-11-22;9(0):101923.
Species: Human
Sample Types: Serum
Applications: ELISA Control

Dienogest May Reduce Estradiol- and Inflammatory Cytokine-Induced Cell Viability and Proliferation and Inhibit the Pathogenesis of Endometriosis: A Cell Culture- and Mouse Model-Based Study
Authors: HJ Kim, SH Kim, YS Oh, SR Lee, HD Chae
Biomedicines, 2022-11-21;10(11):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Anti-inflammatory and pro-anabolic effects of 5-aminosalicylic acid on human inflammatory osteoarthritis models
Authors: K Li, Y Zhu, P Zhang, M Alini, S Grad, Z Li
Journal of Orthopaedic Translation, 2022-10-29;38(0):106-116.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

In Vitro Characterization of a Tissue Renin-Angiotensin System in Human Nucleus Pulposus Cells
Authors: B Saravi, Z Li, V Basoli, S Grad, S Häckel, CE Albers, M Alini, H Schmal, P Obid, G Lang
Cells, 2022-10-28;11(21):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeting hypoxia-induced tumor stemness by activating pathogen-induced stem cell niche defense.
Authors: Bhuyan S, Pal B, Pathak L, Saikia P, Mitra S, Gayan S, Mokhtari R, Li H, Ramana C, Baishya D, Das B
Front Immunol, 2022-09-29;13(0):933329.
Species: Complex Species Category
Sample Types: Whole Cells
Applications: Bioassay

Cytokine responsive networks in human colonic epithelial organoids unveil a molecular classification of inflammatory bowel disease
Authors: P Pavlidis, A Tsakmaki, A Treveil, K Li, D Cozzetto, F Yang, U Niazi, BH Hayee, M Saqi, J Friedman, T Korcsmaros, G Bewick, N Powell
Cell Reports, 2022-09-27;40(13):111439.
Species: Human
Sample Types: Organoid
Applications: Bioassay

Delayed regression of laser-induced choroidal neovascularization in TNFalpha-null mice
Authors: H Iwanishi, O Yamanaka, T Sumioka, S Yasuda, M Miyajima, S Saika
Journal of Cellular and Molecular Medicine, 2022-09-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Improved immunoassay sensitivity and specificity using single-molecule colocalization
Authors: AA Hariri, SS Newman, S Tan, D Mamerow, AM Adams, N Maganzini, BL Zhong, M Eisenstein, AR Dunn, HT Soh
Nature Communications, 2022-09-12;13(1):5359.
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay

DLL4 and VCAM1 enhance the emergence of T cell-competent hematopoietic progenitors from human pluripotent stem cells
Authors: YS Michaels, JM Edgar, MC Major, EL Castle, C Zimmerman, T Yin, A Hagner, C Lau, HH Hsu, MI Ibañez-Rio, LJ Durland, DJHF Knapp, PW Zandstra
Science Advances, 2022-08-24;8(34):eabn5522.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

STUB1 is an intracellular checkpoint for interferon gamma sensing
Authors: S Ng, S Lim, ACN Sim, R Mangadu, A Lau, C Zhang, SB Martinez, A Chandramoh, UM Lim, SSW Ho, SC Chang, P Gopal, LZ Hong, A Schwaid, AZ Fernandis, A Loboda, C Li, U Phan, B Henry, AW Partridge
Scientific Reports, 2022-08-18;12(1):14087.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dermatopontin Influences the Development of Obesity-Associated Colon Cancer by Changes in the Expression of Extracellular Matrix Proteins
Authors: V Catalán, P Domench, J Gómez-Ambr, B Ramírez, S Becerril, A Mentxaka, A Rodríguez, V Valentí, R Moncada, J Baixauli, C Silva, J Escalada, G Frühbeck
International Journal of Molecular Sciences, 2022-08-17;23(16):.
Species: Human
Sample Types: Whole Cells
Applications: Stimulation

Galectin-3 inhibitor GB0139 protects against acute lung injury by inhibiting neutrophil recruitment and activation
Authors: DC Humphries, R Mills, C Boz, BJ McHugh, N Hirani, AG Rossi, A Pedersen, HT Schambye, RJ Slack, H Leffler, UJ Nilsson, W Wang, T Sethi, AC Mackinnon
Frontiers in Pharmacology, 2022-08-08;13(0):949264.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Kynurenine metabolites predict survival in pulmonary arterial hypertension: A role for IL-6/IL-6Ralpha
Authors: Z Cai, S Tian, T Klein, L Tu, LW Geenen, T Koudstaal, AE van den Bo, YB de Rijke, IKM Reiss, E Boersma, C van der Le, M Van Faasse, I Kema, DJ Duncker, KA Boomars, K Tran-Lundm, C Guignabert, D Merkus
Scientific Reports, 2022-07-19;12(1):12326.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In vitro assessment of the anti-inflammatory and skin-moisturizing effects of Filipendula palmata (Pall.) Maxim. On human keratinocytes and identification of its bioactive phytochemicals
Authors: XJ Mi, JK Kim, S Lee, SK Moon, YJ Kim, H Kim
Journal of ethnopharmacology, 2022-07-07;296(0):115523.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hypo-osmotic stress induces the epithelial alarmin IL-33 in the colonic barrier of ulcerative colitis
Authors: MD Gundersen, KB Larsen, KM Johnsen, R Goll, J Florholmen, G Haraldsen
Scientific Reports, 2022-07-07;12(1):11550.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4
Authors: S Wang, B Li, V Solomon, A Fonteh, SI Rapoport, DA Bennett, Z Arvanitaki, HC Chui, PM Sullivan, HN Yassine
Molecular Neurodegeneration, 2022-06-15;17(1):42.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
Authors: E Iverson, K Griswold, D Song, TB Gagliardi, K Hamidzadeh, M Kesimer, S Sinha, M Perry, GA Duncan, MA Scull
MBio, 2022-06-14;0(0):e0105522.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dendrobium nobile Lindley Administration Attenuates Atopic Dermatitis-like Lesions by Modulating Immune Cells
Authors: S Hong, EY Kim, SE Lim, JH Kim, Y Sohn, HS Jung
International Journal of Molecular Sciences, 2022-04-18;23(8):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Secreted NF-kappaB suppressive microbial metabolites modulate gut inflammation
Authors: R Giri, EC Hoedt, S Khushi, AA Salim, AS Bergot, V Schreiber, R Thomas, MA McGuckin, TH Florin, M Morrison, RJ Capon, P Ó Cuív, J Begun
Cell Reports, 2022-04-12;39(2):110646.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effect of probiotic Lactobacillus paracasei on tumor necrosis factor-alpha level in gingival crevicular fluid of patients undergoing impacted third molar removal
Authors: S Banjonjit, M Taweechoti, S Rungsiyano
Journal of oral science, 2022-04-08;0(0):.
Species: Human
Sample Types: Recombinant Protein
Applications: ELISA Standard

The Thermal Dose of Photothermal Therapy Generates Differential Immunogenicity in Human Neuroblastoma Cells
Authors: P Sekhri, DK Ledezma, A Shukla, EE Sweeney, R Fernandes
Cancers, 2022-03-11;14(6):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Synoviocytes from pigmented villonodular synovitis are less sensitive to cadmium-induced cell death than synoviocytes from rheumatoid arthritis.
Authors: H Farese, Farese H, M Noack, Noack M, P Miossec
Sci Rep, 2022-03-09;12(1):3832.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Elucidating mechanisms of genetic cross-disease associations at the PROCR vascular disease locus
Authors: D Stacey, L Chen, PJ Stanczyk, JMM Howson, AM Mason, S Burgess, S MacDonald, J Langdown, H McKinney, K Downes, N Farahi, JE Peters, S Basu, JS Pankow, W Tang, N Pankratz, M Sabater-Ll, PS de Vries, NL Smith, CHARGE Hem, AD Gelinas, DJ Schneider, N Janjic, NJ Samani, S Ye, C Summers, ER Chilvers, J Danesh, DS Paul
Nature Communications, 2022-03-09;13(1):1222.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Administration of probiotics to healthy volunteers: effects on reactivity of intestinal mucosa and systemic leukocytes
Authors: C Stene, A Röme, I Palmquist, C Linninge, G Molin, S Ahrné, LB Johnson, B Jeppsson
BMC gastroenterology, 2022-03-05;22(1):100.
Species: Human
Sample Types: Whole Tissue
Applications: Cell Culture

5,8-Dihydroxy-4 ', 7-dimethoxyflavone Attenuates TNF-alpha-Induced Expression of Vascular Cell Adhesion Molecule-1 through EGFR/PKCalpha/PI3K/Akt/Sp1-Dependent Induction of Heme Oxygenase-1 in Human Cardiac Fibroblasts
Authors: CC Yang, LD Hsiao, YF Shih, HH Lin, CM Yang
Oxidative Medicine and Cellular Longevity, 2022-03-04;2022(0):1372958.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mulberrin confers protection against hepatic fibrosis by Trim31/Nrf2 signaling
Authors: C Ge, J Tan, D Lou, L Zhu, Z Zhong, X Dai, Y Sun, Q Kuang, J Zhao, L Wang, J Liu, B Wang, M Xu
Redox Biology, 2022-02-24;51(0):102274.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MG132 Induces Progerin Clearance and Improves Disease Phenotypes in HGPS-like Patients' Cells
Authors: K Harhouri, P Cau, F Casey, KM Guedenon, Y Doubaj, L Van Malder, G Mejia-Balt, C Bartoli, A De Sandre-, N Lévy
Cells, 2022-02-10;11(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of the Na+/K+-ATPase by cardiac glycosides suppresses expression of the IDO1 immune checkpoint in cancer cells by reducing STAT1 activation
Authors: MA Shandell, AL Capatina, SM Lawrence, WJ Brackenbur, D Lagos
The Journal of Biological Chemistry, 2022-02-09;0(0):101707.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Soluble PD-L1 through alternative polyadenylation works as a decoy in lung cancer immunotherapy
Authors: R Sagawa, S Sakata, B Gong, Y Seto, A Takemoto, S Takagi, H Ninomiya, N Yanagitani, M Nakao, M Mun, K Uchibori, M Nishio, Y Miyazaki, Y Shiraishi, S Ogawa, K Kataoka, N Fujita, K Takeuchi, R Katayama
JCI Insight, 2022-01-11;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tissue Inhibitor of Metalloproteinase-3 Ameliorates Diabetes-Induced Retinal Inflammation
Authors: AM Abu El-Asr, A Ahmad, MI Nawaz, MM Siddiquei, A De Zutter, L Vanbrabant, PW Gikandi, G Opdenakker, S Struyf
Frontiers in Physiology, 2022-01-10;12(0):807747.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Immune regulator LGP2 targets Ubc13/UBE2N to mediate widespread interference with K63 polyubiquitination and NF-kappaB activation
Authors: JJ Lenoir, JP Parisien, CM Horvath
Cell Reports, 2021-12-28;37(13):110175.
Species: Human, Transgenic Human
Sample Types: Transfected Whole Cells, Whole Cells
Applications: Bioassay

Bcl-3 promotes TNF-induced hepatocyte apoptosis by regulating the deubiquitination of RIP1
Authors: Y Hu, H Zhang, N Xie, D Liu, Y Jiang, Z Liu, D Ye, S Liu, X Chen, C Li, Q Wang, X Huang, Y Liu, Y Shi, X Zhang
Cell Death and Differentiation, 2021-12-01;0(0):.
Species: Mouse
Sample Types: In Vivo
Applications: Bioassay

CRISPR/dCas9 Transcriptional Activation of Endogenous Apolipoprotein AI and Paraoxonase 1 in Enterocytes Alleviates Endothelial Cell Dysfunction
Authors: L Toma, T Barb?lat?, GM Sanda, LS Niculescu, AV Sima, CS Stancu
Biomolecules, 2021-11-25;11(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glucose metabolism and pyruvate carboxylase enhance glutathione synthesis and restrict oxidative stress in pancreatic islets
Authors: A Fu, L van Rooyen, L Evans, N Armstrong, D Avizonis, T Kin, GH Bird, A Reddy, ET Chouchani, M Liesa-Roig, LD Walensky, AMJ Shapiro, NN Danial
Cell Reports, 2021-11-23;37(8):110037.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Demystifying the long noncoding RNA landscape of small EVs derived from human mesenchymal stromal cells
Authors: CW Lee, YF Chen, AW Hsiao, AY Wang, OY Shen, BY Wang, LWC Ho, WT Lin, CHJ Choi, OK Lee
Journal of advanced research, 2021-11-19;39(0):73-88.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Histone deacetylase 5 deacetylates the phosphatase PP2A for positively regulating NF-kappaB signaling
Authors: C Xu, J Tang, Q Yang, H Zhao, Y Liu, J Cao, Y Zhou, X Chen, J Chen
The Journal of Biological Chemistry, 2021-11-03;0(0):101380.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Activin/FLRG pathway associates with poor COVID-19 outcomes in hospitalized patients
Authors: M McAleavy, Q Zhang, PJ Ehmann, J Xu, MF Wipperman, D Ajithdoss, L Pan, M Wakai, R Simonson, A Gadi, A Oyejide, SC Hamon, A Boyapati, LG Morton, T Shavlakadz, CA Kyratsous, DJ Glass
Molecular and Cellular Biology, 2021-11-01;0(0):MCB0046721.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Novel cytoplasmic lncRNA IKBKBAS promotes lung adenocarcinoma metastasis by upregulating IKKbeta and consequential activation of NF-kappaB signaling pathway
Authors: Y Xing, Y Lin, Y Zhang, J Hu, J Liu, Y Tian, J Zhao, W Chen, B Han
Cell Death & Disease, 2021-10-26;12(11):1004.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Diverse inflammatory threats modulate astrocytes Ca2+ signaling via connexin43 hemichannels in organotypic spinal slices
Authors: G Panattoni, R Amoriello, C Memo, A Thalhammer, C Ballerini, L Ballerini
Molecular Brain, 2021-10-25;14(1):159.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

Phospholipase A2 enzymes represent a shared pathogenic pathway in psoriasis and pityriasis rubra pilaris
Authors: S Shao, J Chen, WR Swindell, LC Tsoi, X Xing, F Ma, R Uppala, MK Sarkar, O Plazyo, AC Billi, R Wasikowski, KM Smith, P Honore, VE Scott, E Maverakis, JM Kahlenberg, G Wang, NL Ward, PW Harms, JE Gudjonsson
JCI Insight, 2021-10-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Angiotensin II-Induced Long Non-Coding RNA Alivec Regulates Chondrogenesis in Vascular Smooth Muscle Cells
Authors: VA Samara, S Das, MA Reddy, VS Tanwar, K Stapleton, A Leung, M Abdollahi, R Ganguly, L Lanting, R Natarajan
Cells, 2021-10-09;10(10):.
Species: Rat
Sample Types: Whole Cells
Applications: Cell Culture

Fundamentally different roles of neuronal TNF receptors in CNS pathology: TNFR1 and IKKbeta promote microglial responses and tissue injury in demyelination while TNFR2 protects against excitotoxicity in mice
Authors: I Papazian, E Tsoukala, A Boutou, M Karamita, K Kambas, L Iliopoulou, R Fischer, RE Kontermann, MC Denis, G Kollias, H Lassmann, L Probert
Journal of Neuroinflammation, 2021-09-26;18(1):222.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TNF-alpha Increases IP-10 Expression in MCF-7 Breast Cancer Cells via Activation of the JNK/c-Jun Pathways
Authors: S Kochumon, A Al-Sayyar, T Jacob, A Hasan, F Al-Mulla, S Sindhu, R Ahmad
Biomolecules, 2021-09-13;11(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Correction: Monocyte subset redistribution from blood to kidneys in patients with Puumala virus caused hemorrhagic fever with renal syndrome
Authors: S Vangeti, T Strandin, S Liu, J Tauriainen, A Räisänen-S, LE Cabrera, A Hassinen, S Mäkelä, J Mustonen, A Vaheri, O Vapalahti, J Klingström, A Smed-Sören
PloS Pathogens, 2021-08-25;17(8):e1009876.
Species: Human
Sample Types:
Applications: Bioassay

Pro-inflammatory beta cell small extracellular vesicles induce beta cell failure through activation of the CXCL10/CXCR3 axis in diabetes
Authors: N Javeed, TK Her, MR Brown, P Vanderboom, K Rakshit, AM Egan, A Vella, I Lanza, AV Matveyenko
Cell Reports, 2021-08-24;36(8):109613.
Species: Mouse
Sample Types: Whole Cells
Applications: Stimulation

Functional human iPSC-derived alveolar-like cells cultured in a miniaturized 96?Transwell air-liquid interface model
Authors: T Bluhmki, S Traub, AK Müller, S Bitzer, E Schruf, MT Bammert, M Leist, F Gantner, JP Garnett, R Heilker
Scientific Reports, 2021-08-23;11(1):17028.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Oncogene-induced senescence in hematopoietic progenitors features myeloid restricted hematopoiesis, chronic inflammation and histiocytosis
Authors: R Biavasco, E Lettera, K Giannetti, D Gilioli, S Beretta, A Conti, S Scala, D Cesana, P Gallina, M Norelli, L Basso-Ricc, A Bondanza, G Cavalli, M Ponzoni, L Dagna, C Doglioni, A Aiuti, I Merelli, R Di Micco, E Montini
Nature Communications, 2021-07-27;12(1):4559.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cellular senescence promotes endothelial activation through epigenetic alteration, and consequently accelerates atherosclerosis
Authors: S Honda, K Ikeda, R Urata, E Yamazaki, N Emoto, S Matoba
Scientific Reports, 2021-07-16;11(1):14608.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-378a-3p is overexpressed in psoriasis and modulates cell cycle arrest in keratinocytes via targeting BMP2 gene
Authors: W Soonthornc, P Tangtanata, K Meesilpavi, V Dalm, P Kueanjinda, J Wongpiyabo
Scientific Reports, 2021-07-09;11(1):14186.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Protective effects of the knockdown of lncRNA AK139328 against oxygen glucose deprivation/reoxygenation-induced injury in PC12 cells
Authors: L Liu, B Zheng, Z Wang
Molecular Medicine Reports, 2021-07-02;24(3):.
Species: Rat
Sample Types: Cell Culture Supernates

CD146/Soluble CD146 Pathway Is a Novel Biomarker of Angiogenesis and Inflammation in Proliferative Diabetic Retinopathy
Authors: AM Abu El-Asr, MI Nawaz, A Ahmad, MM Siddiquei, E Allegaert, PW Gikandi, G De Hertogh, G Opdenakker
Investigative Ophthalmology & Visual Science, 2021-07-01;62(9):32.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transdifferentiation of Human Fibroblasts into Skeletal Muscle Cells: Optimization and Assembly into Engineered Tissue Constructs through Biological Ligands
Authors: KMA Abdel-Raou, R Rezgui, C Stefanini, JCM Teo, N Christofor
Biology, 2021-06-16;10(6):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis
Authors: K Andelid, K Öst, A Andersson, E Mohamed, Z Jevnikar, LEGW Vanfletere, M Göransson
Respiratory Research, 2021-06-07;22(1):172.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induction of OCT2 contributes to regulate the gene expression program in human neutrophils activated via TLR8
Authors: N Tamassia, F Bianchetto, S Gasperini, S Polletti, E Gardiman, R Ostuni, G Natoli, MA Cassatella
Cell Reports, 2021-05-18;35(7):109143.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Necroptosis pathway blockage attenuates PFKFB3 inhibitor-induced cell viability loss and genome instability in colorectal cancer cells
Authors: S Yan, Q Li, D Zhang, X Wang, Y Xu, C Zhang, D Guo, Y Bao
American journal of cancer research, 2021-05-15;11(5):2062-2080.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RIPK1 activation mediates neuroinflammation and disease progression in multiple sclerosis
Authors: M Zelic, F Pontarelli, L Woodworth, C Zhu, A Mahan, Y Ren, M LaMorte, R Gruber, A Keane, P Loring, L Guo, TH Xia, B Zhang, P Orning, E Lien, A Degterev, T Hammond, D Ofengeim
Cell Reports, 2021-05-11;35(6):109112.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

XPO1 inhibition with selinexor synergizes with proteasome inhibition in neuroblastoma by targeting nuclear export of IkB
Authors: B Galinski, M Luxemburg, Y Landesman, B Pawel, KJ Johnson, SR Master, KW Freeman, DM Loeb, JM Hébert, DA Weiser
Translational Oncology, 2021-05-09;14(8):101114.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4
Authors: S Wang, B Li, V Solomon, A Fonteh, SI Rapoport, DA Bennett, Z Arvanitaki, HC Chui, C Miller, PM Sullivan, HY Wang, HN Yassine
Molecular Neurodegeneration, 2021-04-16;16(1):26.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell-Derived RPE
Authors: SR Sripathi, MW Hu, MM Liu, J Wan, J Cheng, Y Duan, JL Mertz, KJ Wahlin, J Maruotti, CA Berlinicke, J Qian, DJ Zack
Investigative Ophthalmology & Visual Science, 2021-04-01;62(4):1.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure
Authors: P Rueda, J Merlin, S Chimenti, M Feletou, J Paysant, PJ White, A Christopou, PM Sexton, RJ Summers, WN Charman, LT May, CJ Langmead
Frontiers in Pharmacology, 2021-03-11;12(0):628060.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

LL-37-mediated activation of host receptors is critical for defense against group A streptococcal infection
Authors: D Biswas, P Ambalavana, M Ravins, A Anand, A Sharma, KXZ Lim, RYM Tan, HY Lim, A Sol, G Bachrach, V Angeli, E Hanski
Cell Reports, 2021-03-02;34(9):108766.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm
Authors: P Gao, P Gao, J Zhao, S Shan, W Luo, OJ Slivano, W Zhang, A Tabuchi, SA LeMaire, L Maegdefess, YH Shen, JM Miano, HA Singer, X Long
Redox Biology, 2021-02-20;41(0):101903.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Bioassay

ABIN-1 is a key regulator in RIPK1-dependent apoptosis (RDA) and necroptosis, and ABIN-1 deficiency potentiates necroptosis-based cancer therapy in colorectal cancer
Authors: J Cai, D Hu, J Sakya, T Sun, D Wang, L Wang, X Mao, Z Su
Cell Death & Disease, 2021-02-01;12(2):140.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The inflammatory kinase IKK&alpha phosphorylates and stabilizes c-Myc and enhances its activity
Authors: B Moser, B Hochreiter, J Basílio, V Gleitsmann, A Panhuber, A Pardo-Garc, B Hoesel, M Salzmann, U Resch, M Noreen, JA Schmid
Molecular Cancer, 2021-01-18;20(1):16.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dendritic cells focus CTL responses toward highly conserved and topologically important HIV-1 epitopes
Authors: TM Garcia-Bat, ML Palma, RR Anderko, DC Hsu, J Ananworani, BT Korber, GD Gaiha, N Phanuphak, R Thomas, S Tovanabutr, BD Walker, JW Mellors, PA Piazza, E Kroon, SA Riddler, NL Michael, CR Rinaldo, RB Mailliard, I4C and RV
EBioMedicine, 2021-01-12;63(0):103175.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Vascular endothelial ERp72 is involved in the inflammatory response in a rat model of skeletal muscle injury
Authors: NB Khalaf, D Al-?ehatab, DM Fathallah
Molecular Medicine Reports, 2021-01-05;23(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality
Authors: J Stebbing, G Sánchez Ni, M Falcone, S Youhanna, P Richardson, S Ottaviani, JX Shen, C Sommerauer, G Tiseo, L Ghiadoni, A Virdis, F Monzani, LR Rizos, F Forfori, A Avendaño-C, S De Marco, L Carrozzi, F Lena, PM Sánchez-Ju, LG Lacerenza, N Cesira, D Caldevilla, A Perrella, L Niccoli, LS Méndez, D Matarrese, D Goletti, YJ Tan, V Monteil, G Dranitsari, F Cantini, A Farcomeni, S Dutta, SK Burley, H Zhang, M Pistello, W Li, M Mas Romero, F Andrés Pre, RS Simón-Tale, R García-Mol, C Kutter, JH Felce, ZF Nizami, AG Miklosi, JM Penninger, F Menichetti, A Mirazimi, P Abizanda, VM Lauschke
Sci Adv, 2021-01-01;0(0):.
Species: Human
Sample Types: Spheroid
Applications: Spheroid Culture

Acadesine suppresses TNF-&alpha induced complement component 3 (C3), in retinal pigment epithelial (RPE) cells
Authors: NE Efstathiou, GA Moustafa, DE Maidana, EK Konstantin, S Notomi, PRT Barbisan, CD Georgakopo, JW Miller, DG Vavvas
PLoS ONE, 2020-12-23;15(12):e0244307.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fluorofenidone Alleviates Renal Fibrosis by Inhibiting Necroptosis Through RIPK3/MLKL Pathway
Authors: Q Dai, Y Zhang, X Liao, Y Jiang, X Lv, X Yuan, J Meng, Y Xie, Z Peng, Q Yuan, L Tao, L Huang
Frontiers in Pharmacology, 2020-12-16;11(0):534775.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Intracellular role of IL-6 in mesenchymal stromal cell immunosuppression and proliferation
Authors: A Dorronsoro, V Lang, I Ferrin, J Fernández-, L Zabaleta, E Pérez-Ruiz, P Sepúlveda, C Trigueros
Scientific Reports, 2020-12-14;10(1):21853.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A macrophage-specific lncRNA regulates apoptosis and atherosclerosis by tethering HuR in the nucleus
Authors: V Simion, H Zhou, S Haemmig, JB Pierce, S Mendes, Y Tesmenitsk, D Pérez-Crem, JF Lee, AF Chen, N Ronda, B Papotti, JA Marto, MW Feinberg
Nature Communications, 2020-12-01;11(1):6135.
Species: Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Red-COLA1: a human fibroblast reporter cell line for type I collagen transcription
Authors: HH Wong, SH Seet, CC Bascom, RJ Isfort, F Bard
Sci Rep, 2020-11-12;10(1):19723.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

CD4 T-cell immune stimulation of HER2?+?breast cancer cells alters response to trastuzumab in vitro
Authors: PN Song, A Mansur, KJ Dugger, TR Davis, G Howard, TE Yankeelov, AG Sorace
Cancer Cell International, 2020-11-10;20(1):544.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Relative Deficiency of Anti-Inflammatory N-Acylethanolamines Compared to Prostaglandins in Oral Lichen Planus
Authors: L Rankin, S Gouveia-Fi, KP Danielsson, CJ Fowler
Biomedicines, 2020-11-06;8(11):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

&beta-Catenin Regulates Wound Healing and IL-6 Expression in Activated Human Astrocytes
Authors: VV Edara, S Nooka, J Proulx, S Stacy, A Ghorpade, K Borgmann
Biomedicines, 2020-11-06;8(11):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Preclinical validation of therapeutic targets predicted by tensor factorization on heterogeneous graphs
Authors: S Paliwal, A de Giorgio, D Neil, JB Michel, AM Lacoste
Sci Rep, 2020-10-26;10(1):18250.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG
Authors: K Landgraf, N Klöting, M Gericke, N Maixner, E Guiu-Jurad, M Scholz, AV Witte, F Beyer, JT Schwartze, M Lacher, A Villringer, P Kovacs, A Rudich, M Blüher, W Kiess, A Körner
Cell Rep, 2020-10-20;33(3):108295.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

LPS Induces GM-CSF Production by Breast Cancer MDA-MB-231 Cells via Long-Chain Acyl-CoA Synthetase 1
Authors: F Al-Rashed, R Thomas, A Al-Roub, F Al-Mulla, R Ahmad
Molecules, 2020-10-14;25(20):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia
Authors: S Nagel, C Pommerenke, C Meyer, RAF MacLeod, HG Drexler
PLoS ONE, 2020-10-13;15(10):e0240120.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Stearic Acid and TNF-&alpha Co-Operatively Potentiate MIP-1&alpha Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway
Authors: S Kochumon, H Arefanian, R Azim, S Shenouda, T Jacob, N Abu Khalaf, F Al-Rashed, A Hasan, S Sindhu, F Al-Mulla, R Ahmad
Biomedicines, 2020-10-09;8(10):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Proinflammatory cytokines and ARDS pulmonary edema fluid induce CD40 on human mesenchymal stromal cells-A potential mechanism for immune modulation
Authors: EM Wilfong, R Croze, X Fang, M Schwede, E Niemi, GY López, JW Lee, MC Nakamura, MA Matthay
PLoS ONE, 2020-10-06;15(10):e0240319.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

CX3CL1 and IL-15 Promote CD8 T cell chemoattraction in HIV and in atherosclerosis
Authors: S Panigrahi, B Chen, M Fang, D Potashniko, AA Komissarov, A Lebedeva, GM Michaelson, JM Wyrick, SR Morris, SF Sieg, M Paiardini, FJ Villinger, K Harth, VS Kashyap, MJ Cameron, CM Cameron, E Vasilieva, L Margolis, SA Younes, NT Funderburg, DA Zidar, MM Lederman, ML Freeman
PLoS Pathog, 2020-09-25;16(9):e1008885.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Association of tricellulin expression with poor colorectal cancer prognosis and metastasis
Authors: JX Zhang, MB Qin, Z Ye, P Peng, SM Li, Q Song, L Lin, SQ Liu, LH Xie, Y Zhu, JA Huang
Oncology reports, 2020-09-17;44(5):2174-2184.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Circulating miRNAs Associated with Dysregulated Vascular and Trophoblast Function as Target-Based Diagnostic Biomarkers for Preeclampsia
Authors: S Kim, M Park, JY Kim, T Kim, JY Hwang, KS Ha, MH Won, S Ryoo, YG Kwon, YM Kim
Cells, 2020-08-31;9(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Expressions of TSLP, IL-33, and IL-17A in Monocyte Derived Dendritic Cells from Asthma and COPD Patients are Related to Epithelial-Macrophage Interactions
Authors: M Paplinska-, P Misiukiewi, M Proboszcz, P Nejman-Gry, K Gorska, R Krenke
Cells, 2020-08-22;9(9):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Development of a miniaturized 96-Transwell air-liquid interface human small airway epithelial model
Authors: T Bluhmki, S Bitzer, JA Gindele, E Schruf, T Kiechle, M Webster, J Schymeinsk, R Ries, F Gantner, D Bischoff, J Garnett, R Heilker
Sci Rep, 2020-08-03;10(1):13022.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MIP-1alpha Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-alpha Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress
Authors: S Sindhu, N Akhter, A Wilson, R Thomas, H Arefanian, A Al Madhoun, F Al-Mulla, R Ahmad
Cells, 2020-07-29;9(8):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

METTL14 aggravates endothelial inflammation and atherosclerosis by increasing FOXO1 N6-methyladeosine modifications
Authors: D Jian, Y Wang, L Jian, H Tang, L Rao, K Chen, Z Jia, W Zhang, Y Liu, X Chen, X Shen, C Gao, S Wang, M Li
Theranostics, 2020-07-11;10(20):8939-8956.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterization of the TNF and IL-1 systems in human brain and blood after ischemic stroke
Authors: BH Clausen, M Wirenfeldt, SS Høgedal, LH Frich, HH Nielsen, HD Schrøder, K Østergaard, B Finsen, BW Kristensen, KL Lambertsen
Acta Neuropathol Commun, 2020-06-05;8(1):81.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Group V secreted phospholipase A2 plays a protective role against aortic dissection
Authors: K Watanabe, Y Taketomi, Y Miki, K Kugiyama, M Murakami
J. Biol. Chem., 2020-06-01;295(30):10092-10111.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES)
Authors: MY Hsieh, JJ Lin, SH Hsia, JL Huang, KW Yeh, KW Chang, WI Lee
Biomed J, 2020-05-29;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tumor necrosis factor-&alpha regulates skeletal myogenesis by inhibiting SP1 interaction with cis-acting regulatory elements within the Fbxl2 gene promoter
Authors: ME O'Brien, J Londino, M McGinnis, N Weathingto, J Adair, T Suber, V Kagan, K Chen, C Zou, B Chen, J Bon, RK Mallampall
Mol. Cell. Biol., 2020-05-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex
Authors: J Seo, D Seong, YW Nam, CH Hwang, SR Lee, CS Lee, Y Jin, HW Lee, DB Oh, P Vandenabee, J Song
Cell Death Differ., 2020-05-26;0(0):.
Applications: Cell Culture

Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes
Authors: MF Abas?yan?k, K Wolfe, H Van Phan, J Lin, B Laxman, SR White, PA Verhoef, GM Mutlu, B Patel, S Tay
Nat Commun, 2020-05-25;11(1):2607.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study
Authors: D Sinkeviciu, A Aspberg, Y He, AC Bay-Jensen, P Önnerfjord
BMC Rheumatol, 2020-05-12;4(0):30.
Species: Bovine
Sample Types: Whole Tissue
Applications: Bioassay

Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins
Authors: RA Lu, AA Zeki, S Ram-Mohan, N Nguyen, Y Bai, K Chmiel, S Pecic, X Ai, R Krishnan, CC Ghosh
Front Pharmacol, 2020-05-06;11(0):469.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

The Deubiquitinating Enzyme USP20 Regulates the TNFalpha-Induced NF-kappaB Signaling Pathway through Stabilization of p62
Authors: J Ha, M Kim, D Seo, JS Park, J Lee, J Lee, SH Park
Int J Mol Sci, 2020-04-28;21(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Synergistic activation of NF-&kappaB by TNFAIP3 (A20) reduction and UBE2L3 (UBCH7) augment that synergistically elevate lupus risk
Authors: T Kim, SC Bae, C Kang
Arthritis Res. Ther., 2020-04-25;22(1):93.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor &alpha (TNF-&alpha) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-?B) Signaling Pathway
Authors: X Wu, X Deng, J Wang, Q Li
Med. Sci. Monit., 2020-04-23;26(0):e919392.
Species: Human
Sample Types: Whole Cells

Cellular Importin-&alpha3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection
Authors: S Thiele, S Stanelle-B, S Beck, NM Kouassi, M Zickler, M Müller, B Tuku, P Resa-Infan, D van Riel, M Alawi, T Günther, F Rother, S Hügel, S Reimering, A McHardy, A Grundhoff, W Brune, A Osterhaus, M Bader, E Hartmann, G Gabriel
Cell Rep, 2020-04-21;31(3):107549.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations
Authors: A Nikonova, M Khaitov, DJ Jackson, S Traub, MB Trujillo-T, DA Kudlay, AS Dvornikov, A Del-Rosari, R Valenta, LA Stanciu, R Khaitov, SL Johnston
EBioMedicine, 2020-04-09;54(0):102734.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration
Authors: Y Wooff, N Fernando, JHC Wong, C Dietrich, R Aggio-Bruc, JA Chu-Tan, AAB Robertson, SL Doyle, SM Man, R Natoli
Sci Rep, 2020-02-10;10(1):2263.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Monocyte chemoattractant protein?1 promotes the proliferation, migration and differentiation potential of fibroblast?like synoviocytes via the PI3K/P38 cellular signaling pathway
Authors: X Tong, H Zeng, P Gu, K Wang, H Zhang, X Lin
Mol Med Rep, 2020-01-29;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Cell Culture

Increasing the Medium Osmolarity Reduces the Inflammatory Status of Human OA Chondrocytes and Increases Their Responsiveness to GDF-5
Authors: T Mang, S Lindemann, A Gigout
Int J Mol Sci, 2020-01-14;21(2):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma
Authors: M Tochimoto, Y Oguri, M Hashimura, R Konno, T Matsumoto, A Yokoi, Y Kodera, M Saegusa
Lab. Invest., 2019-12-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome
Authors: CC Gross, C Meyer, U Bhatia, L Yshii, I Kleffner, J Bauer, AR Tröscher, A Schulte-Me, S Herich, T Schneider-, H Plate, T Kuhlmann, M Schwaninge, W Brück, M Pawlitzki, DA Laplaud, D Loussouarn, J Parratt, M Barnett, ME Buckland, TA Hardy, SW Reddel, M Ringelstei, J Dörr, B Wildemann, M Kraemer, H Lassmann, R Höftberger, E Beltrán, K Dornmair, N Schwab, L Klotz, SG Meuth, G Martin-Blo, H Wiendl, R Liblau
Nat Commun, 2019-12-18;10(1):5779.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

NF-kappaB-mediated inhibition of microRNA-149-5p regulates Chitinase-3-like 1 expression in human airway epithelial cells
Authors: K Hübner, D Karwelat, E Pietsch, I Beinborn, S Winterberg, K Bedenbende, BJ Benedikter, B Schmeck, E Vollmeiste
Cell. Signal., 2019-12-16;67(0):109498.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The role of endothelial MERTK during the inflammatory response in lungs
Authors: Y Li, ES Wittchen, E Monaghan-B, C Hahn, HS Earp, CM Doerschuk, K Burridge
PLoS ONE, 2019-12-05;14(12):e0225051.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum
Authors: A Stumpf, T Brandstett, J Hübner, J Rühe
PLoS ONE, 2019-12-02;14(12):e0225525.
Species: Human
Sample Types: Serum
Applications: ELISA Standard

Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model
Authors: X An, G Liao, Y Chen, A Luo, J Liu, Y Yuan, L Li, L Yang, H Wang, F Liu, G Yang, S Yi, Y Li, J Cheng, Y Lu
Stem Cell Res Ther, 2019-12-02;10(1):363.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients
Authors: D Deli?, K Wolk, R Schmid, O Gabrielyan, D Christou, K Rieber, M Rolser, I Jakob, F Wiech, M Griesser, C Wohnhaas, G Kokolakis, E Witte-Händ, P Baum, R Sabat
J. Dermatol. Sci., 2019-11-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation
Authors: N Uyama, H Tsutsui, S Wu, K Yasuda, E Hatano, XY Qin, S Kojima, J Fujimoto
Sci Rep, 2019-11-26;9(1):17558.
Species: Human
Sample Types: Whole Tissue
Applications: IHC-P

Intra-pancreatic tissue-derived mesenchymal stromal cells: a promising therapeutic potential with anti-inflammatory and pro-angiogenic profiles
Authors: B Khiatah, M Qi, W Du, K T-Chen, KM van Megen, RG Perez, JS Isenberg, F Kandeel, BO Roep, HT Ku, IH Al-Abdulla
Stem Cell Res Ther, 2019-11-15;10(1):322.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like Synoviocytes
Authors: J Lin, Y Yu, X Wang, Y Ke, C Sun, L Yue, G Xu, B Xu, L Xu, H Cao, D Xu, N Olsen, W Chen
J Immunol Res, 2019-11-14;2019(0):6929286.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation
Authors: KA Jha, M Pentecost, R Lenin, J Gentry, L Klaic, N Del Mar, A Reiner, CH Yang, LM Pfeffer, N Sohl, R Gangaraju
Stem Cell Res Ther, 2019-11-05;10(1):318.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE
Authors: H Wang, E Kunz, GJ Stoddard, WW Hauswirth, ME Hartnett
Sci Rep, 2019-10-31;9(1):15732.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma
Authors: X Sun, T Hou, E Cheung, TN Iu, VW Tam, IM Chu, MS Tsang, PK Chan, CW Lam, CK Wong
Cell. Mol. Immunol., 2019-10-23;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression
Authors: J Merola, M Reschke, RW Pierce, L Qin, S Spindler, T Baltazar, TD Manes, F Lopez-Gira, G Li, LG Bracaglia, C Xie, N Kirkiles-S, WM Saltzman, GT Tietjen, G Tellides, JS Pober
JCI Insight, 2019-10-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals
Authors: ER Wonderlich, K Subramania, B Cox, A Wiegand, C Lackman-Sm, MJ Bale, M Stone, R Hoh, MF Kearney, F Maldarelli, SG Deeks, MP Busch, RG Ptak, DA Kulpa
PLoS Pathog., 2019-10-14;15(10):e1008074.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele
Authors: H Al-Mossawi, N Yager, CA Taylor, E Lau, S Danielli, J de Wit, J Gilchrist, I Nassiri, EA Mahe, W Lee, L Rizvi, S Makino, J Cheeseman, M Neville, JC Knight, P Bowness, BP Fairfax
Nat Commun, 2019-10-08;10(1):4575.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress
Authors: C Merriman, D Fu
J. Biol. Chem., 2019-10-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Progranulin attenuates liver fibrosis by downregulating the inflammatory response
Authors: W Yoo, J Lee, KH Noh, S Lee, D Jung, MH Kabir, D Park, C Lee, KS Kwon, JS Kim, S Kim
Cell Death Dis, 2019-10-07;10(10):758.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Expression of connective tissue growth factor as a prognostic indicator and its possible involvement in the aggressive properties of epithelial ovarian carcinoma
Authors: A Shimbo, H Kajiyama, S Tamauchi, N Yoshikawa, Y Ikeda, K Nishino, S Suzuki, K Niimi, J Sakata, F Kikkawa
Oncol. Rep., 2019-10-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tissue-regenerative potential of the secretome of gamma-irradiated peripheral blood mononuclear cells is mediated via TNFRSF1B-induced necroptosis
Authors: E Simader, L Beer, M Laggner, V Vorstandle, A Gugerell, M Erb, P Kalinina, D Copic, D Moser, A Spittler, E Tschachler, H Jan Ankers, M Mildner
Cell Death Dis, 2019-09-30;10(10):729.
Species: Human
Sample Types: Recombinant Protein
Applications: Bioassay

Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity
Authors: NW Zammit, OM Siggs, PE Gray, K Horikawa, DB Langley, SN Walters, SR Daley, C Loetsch, J Warren, JY Yap, D Cultrone, A Russell, EK Malle, JE Villanueva, MJ Cowley, V Gayevskiy, ME Dinger, R Brink, D Zahra, G Chaudhri, G Karupiah, B Whittle, C Roots, E Bertram, M Yamada, Y Jeelall, A Enders, BE Clifton, PD Mabbitt, CJ Jackson, SR Watson, CN Jenne, LL Lanier, T Wiltshire, MH Spitzer, GP Nolan, F Schmitz, A Aderem, BT Porebski, AM Buckle, DW Abbott, JB Ziegler, ME Craig, P Benitez-Ag, J Teo, SG Tangye, C King, M Wong, MP Cox, W Phung, J Tang, W Sandoval, IE Wertz, D Christ, CC Goodnow, ST Grey
Nat. Immunol., 2019-09-18;20(10):1299-1310.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression
Authors: J Ren, M Smid, J Iaria, DCF Salvatori, H van Dam, HJ Zhu, JWM Martens, P Ten Dijke
Breast Cancer Res., 2019-09-18;21(1):109.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The Possible Role of Neutrophils in the Induction of Osteoclastogenesis
Authors: CGJ Moonen, TJ de Vries, P Rijkschroe, PE Poubelle, EA Nicu, BG Loos
J Immunol Res, 2019-09-15;2019(0):8672604.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models
Authors: JC Chamcheu, S Esnault, VM Adhami, AL Noll, S Banang-Mbe, T Roy, SS Singh, S Huang, KG Kousoulas, H Mukhtar
Cells, 2019-09-15;8(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An Autocrine Wnt5a Loop Promotes NF-kappaB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma
Authors: G Barbero, MV Castro, MB Villanueva, MJ Quezada, NB Fernández, S DeMorrow, P Lopez-Berg
Cells, 2019-09-10;8(9):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha
Authors: X Qiu, X Wang, J Qiu, Y Zhu, T Liang, B Gao, Z Wu, C Lian, Y Peng, A Liang, P Su, D Huang
Stem Cells Int, 2019-09-05;2019(0):6403967.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effect of Ionizing Radiation on Human EA.hy926 Endothelial Cells under Inflammatory Conditions and Their Interactions with A549 Tumour Cells
Authors: S Schröder, S Broese, J Baake, D Juer beta, S Kriesen, G Hildebrand, K Manda
J Immunol Res, 2019-09-02;2019(0):9645481.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation
Authors: C Jiang, SJ Trudeau, TC Cheong, R Guo, M Teng, LW Wang, Z Wang, C Pighi, C Gautier-Co, Y Ma, S Jiang, C Wang, B Zhao, L Paillard, JG Doench, R Chiarle, BE Gewurz
Cell Rep, 2019-07-30;28(5):1307-1322.e8.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Low concentration flufenamic acid enhances osteogenic differentiation of mesenchymal stem cells and suppresses bone loss by inhibition of the NF-κB signaling pathway
Authors: X Liu, Z Li, H Liu, Y Zhu, D Xia, S Wang, R Gu, W Wu, P Zhang, Y Liu, Y Zhou
Stem Cell Res Ther, 2019-07-19;10(1):213.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

The P-selectin and PSGL-1 axis accelerates atherosclerosis via activation of dendritic cells by the TLR4 signaling pathway
Authors: Z Ye, L Zhong, S Zhu, Y Wang, J Zheng, S Wang, J Zhang, R Huang
Cell Death Dis, 2019-07-01;10(7):507.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The expression of NOD2, NLRP3 and NLRC5 and renal injury in anti-neutrophil cytoplasmic antibody-associated vasculitis
Authors: LY Wang, XJ Sun, M Chen, MH Zhao
J Transl Med, 2019-06-11;17(1):197.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
Authors: BD Bryson, TR Rosebrock, FG Tafesse, CY Itoh, A Nibasumba, GH Babunovic, B Corleis, C Martin, C Keegan, P Andrade, S Realegeno, D Kwon, RL Modlin, SM Fortune
Nat Commun, 2019-05-27;10(1):2329.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses
Authors: R van Dalen, JS De La Cruz, M Rumpret, FF Fuchsberge, NH van Teijli, J Hanske, C Rademacher, TBH Geijtenbee, JAG van Strijp, C Weidenmaie, A Peschel, DH Kaplan, NM van Sorge
MBio, 2019-05-14;10(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Functional characterization of SLC26A3 c.392C>G (p.P131R) mutation in intestinal barrier function using CRISPR/CAS9-created cell models
Authors: N Zhang, DP Heruth, W Wu, LQ Zhang, MN Nsumu, K Shortt, K Li, X Jiang, B Wang, C Friesen, DY Li, SQ Ye
Cell Biosci, 2019-05-14;9(0):40.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Differential modulation of CXCL8 versus CXCL10, by cytokines, PPAR-gamma, or PPAR-alpha agonists, in primary cells from Graves' disease and ophthalmopathy
Authors: SM Ferrari, F Ragusa, SR Paparo, F Nasini, M Nardi, SS Franceschi, P Fallahi, A Antonelli
Autoimmun Rev, 2019-05-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats
Authors: N Wang, C Luo, H Liu, X Yang, B Hu, W Zhang, B Li, Y Zhu, G Zhu, X Shen, C Peng, Z Shi
Viruses, 2019-04-24;11(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Xanthatin inhibits STAT3 and NF-?B signalling by covalently binding to JAK and IKK kinases
Authors: M Liu, CQ Xiao, MW Sun, MJ Tan, LH Hu, Q Yu
J. Cell. Mol. Med., 2019-04-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Glucocorticoid-dependent expression of IAP participates in the protection against TNF-mediated cytotoxicity in MCF7 cells
Authors: IB Mitre-Agui, T Barrios-Ga, VM Ruiz-Lopez, AJ Cabrera-Qu, NR Mejia-Domi, JL Ventura-Ga, D Moreno-Mit, A Aranda-Gut, J Mejia-Rang, AR Escalona-G, Y Chavarri-G, A Leon-Del-R, A Zentella-D
BMC Cancer, 2019-04-15;19(1):356.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis
Authors: MR Hadjichara, BT Roux, E Csomor, CA Feghali-Bo, LA Murray, DL Clarke, MA Lindsay
Sci Rep, 2019-04-15;9(1):6020.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neutrophil GM-CSF receptor dynamics in acute lung injury
Authors: S De Alessan, GJ Ferguson, AJ Dodd, JK Juss, A Devaprasad, S Piper, O Wyatt, H Killick, DJ Corkill, ES Cohen, A Pandit, TRDJ Radstake, R Simmonds, AM Condliffe, MA Sleeman, AS Cowburn, DK Finch, ER Chilvers
J. Leukoc. Biol., 2019-04-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1
Authors: J Kristoff, ML Palma, TM Garcia-Bat, C Shen, N Sluis-Crem, P Gupta, CR Rinaldo, RB Mailliard
EBioMedicine, 2019-04-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TGF-?1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM
Authors: K Wang, S Fang, Q Liu, J Gao, X Wang, H Zhu, Z Zhu, F Ji, J Wu, Y Ma, L Hu, X Shen, D Gao, J Zhu, P Liu, H Zhou
EBioMedicine, 2019-03-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Synthesis and Biological Evaluation of Fangchinoline Derivatives as Anti-Inflammatory Agents through Inactivation of Inflammasome
Authors: T Liu, Q Zeng, X Zhao, W Wei, Y Li, H Deng, D Song
Molecules, 2019-03-23;24(6):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Physicochemical characterization and phase I study of CMAB008, an infliximab biosimilar produced by a different expression system
Authors: Q An, Y Zheng, Y Zhao, T Liu, H Guo, D Zhang, W Qian, H Wang, Y Guo, S Hou, J Li
Drug Des Devel Ther, 2019-03-12;13(0):791-805.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma
Authors: B Podder, C Guttà, J Rožanc, E Gerlach, M Feoktistov, D Panayotova, LG Alexopoulo, M Leverkus, M Rehm
Cell Death Differ., 2019-03-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
Cell Stem Cell, 2019-03-07;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A Novel TNF-?-Targeting Aptamer for TNF-?-Mediated Acute Lung Injury and Acute Liver Failure
Authors: WY Lai, JW Wang, BT Huang, EP Lin, PC Yang
Theranostics, 2019-02-28;9(6):1741-1751.
Species: Human
Sample Types: DNA
Applications: Bioassay

Cortistatin binds to TNF-? receptors and protects against osteoarthritis
Authors: Y Zhao, Y Li, R Qu, X Chen, W Wang, C Qiu, B Liu, X Pan, L Liu, K Vasilev, J Hayball, S Dong, W Li
EBioMedicine, 2019-02-28;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Trimethylamine N-oxide promotes tissue factor expression and activity in vascular endothelial cells: A new link between trimethylamine N-oxide and atherosclerotic thrombosis
Authors: X Cheng, X Qiu, Y Liu, C Yuan, X Yang
Thromb. Res., 2019-02-23;177(0):110-116.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LncRNA Meg3 protects endothelial function by regulating the DNA damage response
Authors: MS Shihabudee, X Cheng, M Moran, S Haemmig, MJ Naldrett, S Alvarez, MW Feinberg, X Sun
Nucleic Acids Res., 2019-02-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Extrinsic or Intrinsic Apoptosis by Curcumin and Light: Still a Mystery
Authors: V Laubach, R Kaufmann, A Bernd, S Kippenberg, N Zöller
Int J Mol Sci, 2019-02-19;20(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye
Authors: K Spekker-Bo, CM Ufermann, M Maywald, A Zimmermann, A Domröse, C Woite, W Däubener, SK Eller
Int J Mol Sci, 2019-02-16;20(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer
Authors: T Kaprio, T Rasila, J Hagström, H Mustonen, P Lankila, C Haglund, LC Andersson
PLoS ONE, 2019-02-15;14(2):e0211564.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling
Authors: Y Wang, Y Liu, M Zhang, L Lv, X Zhang, P Zhang, Y Zhou
Stem Cell Res Ther, 2019-02-13;10(1):57.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis
Authors: JC de Quaglia, AM Della Cole, TP Gardizani, GG Romagnoli, R Kaneno, LA Dias-Melic
J Immunol Res, 2019-02-06;2019(0):1529189.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Autoimmune rheumatic disease IgG has differential effects upon neutrophil integrin activation that is modulated by the endothelium
Authors: AA Khawaja, C Pericleous, VM Ripoll, JC Porter, IP Giles
Sci Rep, 2019-02-04;9(1):1283.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate
Authors: M Bobardt, J Kuo, U Chatterji, S Chanda, SJ Little, N Wiedemann, G Vuagniaux, PA Gallay
PLoS ONE, 2019-02-04;14(2):e0211746.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis
Authors: BA Kane, H An, P Rajasekari, HP McNeil, K Bryant, N Tedla
Sci Rep, 2019-02-04;9(1):1149.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS
Authors: T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker
Cancer Res., 2019-02-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system
Authors: S Murakami, R Matsumoto, T Kanamori
Sci Rep, 2019-01-24;9(1):671.
Species: Human
Sample Types: Recombinant Protein
Applications: ELISA (Capture)

Rifamycin SV exhibits strong anti-inflammatory in�vitro activity through pregnane X receptor stimulation and NF?B inhibition
Authors: C Rosette, FJ Agan, N Rosette, L Moro, A Mazzetti, C Hassan, M Gerloni
Drug Metab. Pharmacokinet., 2019-01-17;34(3):172-180.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes
Authors: SE Jin, H Ha, HK Shin, CS Seo
Molecules, 2019-01-11;24(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CD44 Assists the Topical Anti-Psoriatic Efficacy of Curcumin-Loaded Hyaluronan-Modified Ethosomes: A New Strategy for Clustering Drug in Inflammatory Skin
Authors: Y Zhang, Q Xia, Y Li, Z He, Z Li, T Guo, Z Wu, N Feng
Theranostics, 2019-01-01;9(1):48-64.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Intravascular heavy chain-modification of hyaluronan during endotoxic shock
Authors: K Ni, A Gill, D Cao, K Koike, KS Schweitzer, S Garantziot, I Petrache
Biochem Biophys Rep, 2018-12-26;17(0):114-121.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cell Size-Based Decision-Making of a Viral Gene Circuit
Authors: K Bohn-Wippe, EN Tevonian, Y Lu, MY Huang, MR Megaridis, RD Dar
Cell Rep, 2018-12-26;25(13):3844-3857.e5.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tumor necrosis factor-like weak inducer of apoptosis induces inflammation in Graves' orbital fibroblasts
Authors: SJ Lee, J Kim, J Ko, EJ Lee, HJ Koh, JS Yoon
PLoS ONE, 2018-12-21;13(12):e0209583.
Species: Human
Sample Types: Whole Cells

Long Non-Coding RNA Urothelial Carcinoma Associated 1 Promotes Proliferation, Migration and Invasion of Osteosarcoma Cells by Regulating microRNA-182
Authors: Q Li, W Xing, X Gong, Y Wang
Cell. Physiol. Biochem., 2018-11-27;51(3):1149-1163.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence
Authors: M Rentschler, Y Chen, J Pahl, L Soria-Mart, H Braumüller, E Brenner, O Bischof, M Röcken, T Wieder
Cell. Physiol. Biochem., 2018-11-26;51(3):1103-1118.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Agrimonia procera exerts antimicrobial effects, modulates the expression of defensins and cytokines in colonocytes and increases the immune response in lipopolysaccharide-challenged piglets
Authors: T Gräber, H Kluge, S Granica, G Horn, J Kalbitz, C Brandsch, A Breitenste, C Brütting, GI Stangl
BMC Vet. Res., 2018-11-15;14(1):346.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Astrocyte expression of the Drosophila TNF-alpha homologue, Eiger, regulates sleep in flies
Authors: WM Vanderheyd, AG Goodman, RH Taylor, MG Frank, HPA Van Dongen, JR Gerstner
PLoS Genet., 2018-10-31;14(10):e1007724.
Species: Drosophila
Sample Types: In Vivo
Applications: In Vivo

IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment
Authors: L Mercurio, M Morelli, C Scarponi, EZ Eisenmesse, N Doti, G Pagnanelli, E Gubinelli, C Mazzanti, A Cavani, M Ruvo, CA Dinarello, C Albanesi, S Madonna
Cell Death Dis, 2018-10-30;9(11):1104.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Protective mechanisms of resveratrol derivatives against TNF-?-induced inflammatory responses in rat mesangial cells
Authors: IT Lee, CF Lin, YL Huang, KY Chong, MF Hsieh, TH Huang, CY Cheng
Cytokine, 2018-10-30;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines
Authors: S Perriot, A Mathias, G Perriard, M Canales, N Jonkmans, N Merienne, C Meunier, L El Kassar, AL Perrier, DA Laplaud, M Schluep, N Déglon, R Du Pasquie
Stem Cell Reports, 2018-10-25;11(5):1199-1210.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Divergent TCR-Initiated Calcium Signals Govern Recruitment versus Activation of Human Alloreactive Effector Memory T Cells by Endothelial Cells
Authors: TD Manes, V Wang, JS Pober
J. Immunol., 2018-10-19;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anacardic acid suppresses fibroblast-like synoviocyte proliferation and invasion and ameliorates collagen-induced arthritis in a mouse model
Authors: GH Yang, C Zhang, N Wang, Y Meng, YS Wang
Cytokine, 2018-09-28;111(0):350-356.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Catalase Enhances Viability of Human Chondrocytes in Culture by Reducing Reactive Oxygen Species and Counteracting Tumor Necrosis Factor-?-Induced Apoptosis
Authors: S Li, X Yang, Z Feng, P Wang, W Zhu, S Cui
Cell. Physiol. Biochem., 2018-09-27;49(6):2427-2442.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activation of calcium-sensing receptor by allosteric agonists cinacalcet and AC-265347 abolishes the 1,25(OH)2D3-induced Ca2+ transport: Evidence that explains how the intestine prevents excessive Ca2+ absorption
Authors: K Wongdee, M Rodrat, C Keadsai, W Jantarajit, J Teerapornp, J Thongbunch, N Charoenpha
Arch. Biochem. Biophys., 2018-09-11;657(0):15-22.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Presenilin 1 Regulates NF-?B Activation via Association with Breakpoint Cluster Region and Casein Kinase II
Authors: Y Tanaka, L Sabharwal, M Ota, I Nakagawa, JJ Jiang, Y Arima, H Ogura, M Okochi, M Ishii, D Kamimura, M Murakami
J. Immunol., 2018-09-10;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes
Authors: SL Figenschau, E Knutsen, I Urbarova, C Fenton, B Elston, M Perander, ES Mortensen, KA Fenton
Sci Rep, 2018-08-06;8(1):11720.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion
Authors: S Ishii, T Isozaki, H Furuya, H Takeuchi, Y Tsubokura, K Inagaki, T Kasama
Arthritis Res. Ther., 2018-08-02;20(1):159.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-?
Authors: M Schwede, EM Wilfong, RL Zemans, PJ Lee, C Dos Santos, X Fang, MA Matthay
Physiol Rep, 2018-08-01;6(16):e13831.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress
Authors: V Tisato, S Gallo, E Melloni, C Celeghini, A Passaro, G Zauli, P Secchiero, C Bergamini, A Trentini, G Bonaccorsi, G Valacchi, G Zuliani, C Cervellati
Mediators Inflamm., 2018-07-26;2018(0):9629537.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

XAF1 forms a positive feedback loop with IRF-1 to drive apoptotic stress response and suppress tumorigenesis
Authors: SI Jeong, JW Kim, KP Ko, BK Ryu, MG Lee, HJ Kim, SG Chi
Cell Death Dis, 2018-07-24;9(8):806.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Elevated Expression of AXL May Contribute to the Epithelial-to-Mesenchymal Transition in Inflammatory Bowel Disease Patients
Authors: É Boros, Z Kellermaye, P Balogh, G Strifler, A Vörös, P Sarlós, Á Vincze, C Varga, I Nagy
Mediators Inflamm., 2018-07-22;2018(0):3241406.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sodium Butyrate Attenuates Diarrhea in Weaned Piglets and Promotes Tight Junction Protein Expression in Colon in a GPR109A-Dependent Manner
Authors: W Feng, Y Wu, G Chen, S Fu, B Li, B Huang, D Wang, W Wang, J Liu
Cell. Physiol. Biochem., 2018-06-27;47(4):1617-1629.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Induction of innate immune memory via microRNA targeting of chromatin remodelling factors
Authors: JJ Seeley, RG Baker, G Mohamed, T Bruns, MS Hayden, SD Deshmukh, DE Freedberg, S Ghosh
Nature, 2018-06-27;559(7712):114-119.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Proton irradiation orchestrates macrophage reprogramming through NF?B signaling
Authors: G Genard, AC Wera, C Huart, B Le Calve, S Penninckx, A Fattacciol, T Tabarrant, C Demazy, N Ninane, AC Heuskin, S Lucas, C Michiels
Cell Death Dis, 2018-06-27;9(7):728.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lipoxin A4 Attenuates the Inflammatory Response in Stem Cells of the Apical Papilla via ALX/FPR2
Authors: A Gaudin, M Tolar, OA Peters
Sci Rep, 2018-06-11;8(1):8921.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation
Authors: JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani
Cell Death Dis, 2018-06-04;9(6):665.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Synergistic effect of interleukin-17 and tumor necrosis factor-α on inflammatory response in hepatocytes through interleukin-6 dependent and independent pathways
Authors: A Beringer, N Thiam, J Molle, B Bartosch, P Miossec
Clin. Exp. Immunol., 2018-05-31;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy
Authors: SU Seo, SM Woo, HS Lee, SH Kim, KJ Min, TK Kwon
Oncogene, 2018-05-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer
Authors: AL Means, TJ Freeman, J Zhu, LG Woodbury, P Marincola-, C Wu, AR Meyer, CJ Weaver, C Padmanabha, H An, J Zi, BC Wessinger, R Chaturvedi, TD Brown, NG Deane, RJ Coffey, KT Wilson, JJ Smith, CL Sawyers, JR Goldenring, SV Novitskiy, MK Washington, C Shi, RD Beauchamp
Cell Mol Gastroenterol Hepatol, 2018-05-24;6(3):257-276.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Hyaluronic Acid Influence on Normal and Osteoarthritic Tissue-Engineered Cartilage
Authors: S Hemmati-Sa, J Ringe, T Dehne, R Haag, M Sittinger
Int J Mol Sci, 2018-05-19;19(5):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
Authors: AE Dodi, IO Ajayi, C Chang, M Beard, SL Ashley, SK Huang, VJ Thannickal, DJ Tschumperl, TH Sisson, JC Horowitz
Respir. Res., 2018-05-10;19(1):91.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A20 regulates canonical wnt-signaling through an interaction with RIPK4
Authors: BN Nakamura, A Glazier, MG Kattah, B Duong, Y Jia, D Campo, L Shao
PLoS ONE, 2018-05-02;13(5):e0195893.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anisakis pegreffii impacts differentiation and function of human dendritic cells
Authors: C Napoletano, S Mattiucci, A Colantoni, F Battisti, IG Zizzari, H Rahimi, M Nuti, A Rughetti
Parasite Immunol., 2018-05-01;0(0):e12527.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms
Authors: E Vorkapic, A Kunath, D Wågsäter
Mol Med Rep, 2018-04-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
Authors: M Boyd, M Thodberg, M Vitezic, J Bornholdt, K Vitting-Se, Y Chen, M Coskun, Y Li, BZS Lo, P Klausen, P Jan Schwei, AG Pedersen, N Rapin, K Skovgaard, K Dahlgaard, R Andersson, TB Terkelsen, B Lilje, JT Troelsen, AM Petersen, KB Jensen, I Gögenur, P Thielsen, JB Seidelin, OH Nielsen, JT Bjerrum, A Sandelin
Nat Commun, 2018-04-25;9(1):1661.
Species: Human
Sample Types: Organoids
Applications: Bioassay

The proximal tubular ?7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction
Authors: H Kim, SR Kim, J Je, K Jeong, S Kim, HJ Kim, KC Chang, SW Park
Exp. Mol. Med., 2018-04-20;50(4):40.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling
Authors: JP Parisien, JJ Lenoir, R Mandhana, KR Rodriguez, K Qian, AM Bruns, CM Horvath
EMBO Rep., 2018-04-16;0(0):.
Species: Human
Sample Types: Transfected Whole Cells
Applications: Bioassay

Lymphatic exosomes promote dendritic cell migration along guidance cues
Authors: M Brown, LA Johnson, DA Leone, P Majek, K Vaahtomeri, D Senfter, N Bukosza, H Schachner, G Asfour, B Langer, R Hauschild, K Parapatics, YK Hong, KL Bennett, R Kain, M Detmar, M Sixt, DG Jackson, D Kerjaschki
J. Cell Biol., 2018-04-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Matrix metalloproteinase-9 (MMP9) is involved in the TNF-α-induced fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 cancer cells
Authors: J Weiler, M Mohr, KS Zänker, T Dittmar
Cell Commun. Signal, 2018-04-10;16(1):14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
Authors: R Drolia, S Tenguria, AC Durkes, JR Turner, AK Bhunia
Cell Host Microbe, 2018-04-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

High-Mobility Group Box 1 in Dry Eye Inflammation
Authors: C Lema, RY Reins, RL Redfern
Invest. Ophthalmol. Vis. Sci., 2018-04-01;59(5):1741-1750.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties
Authors: M Gabl, M Sundqvist, A Holdfeldt, S Lind, J Mårtensson, K Christenso, T Marutani, C Dahlgren, H Mukai, H Forsman
J. Immunol., 2018-03-30;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Restoration of E-cadherin by PPBICA protects against cisplatin-induced acute kidney injury by attenuating inflammation and programmed cell death
Authors: L Gao, MM Liu, HM Zang, QY Ma, Q Yang, L Jiang, GL Ren, HD Li, WF Wu, JN Wang, B Wei, XQ Liu, C Jiang, C Huang, J Li, XM Meng
Lab. Invest., 2018-03-26;0(0):.
Species: Mouse
Sample Types: Whole Cells
Applications: Bioassay

Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus
Authors: D Sireesh, U Dhamodhara, K Ezhilarasi, V Vijay, KM Ramkumar
Sci Rep, 2018-03-23;8(1):5126.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Voriconazole-induced photocarcinogenesis is promoted by aryl hydrocarbon receptor-dependent COX-2 upregulation
Authors: S Ikeya, JI Sakabe, T Yamada, T Naito, Y Tokura
Sci Rep, 2018-03-22;8(1):5050.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Strigolactone GR24 and pinosylvin attenuate adipogenesis and inflammation of white adipocytes
Authors: S Modi, N Yaluri, T Kokkola
Biochem. Biophys. Res. Commun., 2018-03-21;0(0):.
Species: Mouse
Sample Types: 3T3-L1 adipocytes
Applications: Bioassay

Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients
Authors: CM Dickinson, BW LeBlanc, MM Edhi, DS Heffernan, MH Faridi, V Gupta, WG Cioffi, X O'Brien, JS Reichner
J Intensive Care, 2018-03-15;6(0):19.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Unraveling the interplay between senescent dermal fibroblasts and cutaneous squamous cell carcinoma cell lines at different stages of tumorigenesis
Authors: M Toutfaire, E Dumortier, A Fattacciol, MV Steenbrugg, CM Proby, F Debacq-Cha
Int. J. Biochem. Cell Biol., 2018-03-14;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Sulforaphane rescues amyloid-? peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages
Authors: KA Jhang, JS Park, HS Kim, YH Chong
J Neuroinflammation, 2018-03-12;15(1):75.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Nucleoside Diphosphate Kinase-3 (NME3) Enhances TLR5-Induced NF-?B Activation
Authors: K Flentie, C Gonzalez, B Kocher, Y Wang, H Zhu, J Marasa, D Piwnica-Wo
Mol. Cancer Res., 2018-03-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LRRC15 promotes osteogenic differentiation of mesenchymal stem cells by modulating p65 cytoplasmic/nuclear translocation
Authors: Y Wang, Y Liu, M Zhang, L Lv, X Zhang, P Zhang, Y Zhou
Stem Cell Res Ther, 2018-03-09;9(1):65.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The induced RNA-binding protein, HuR targets 3'-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis
Authors: K Ouhara, S Munenaga, M Kajiya, K Takeda, S Matsuda, Y Sato, Y Hamamoto, T Iwata, S Yamasaki, K Akutagawa, N Mizuno, T Fujita, E Sugiyama, H Kurihara
Clin. Exp. Immunol., 2018-03-08;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients
Authors: E Canto, N Isobe, A Didonna, SL Hauser, JR Oksenberg
J Neuroinflammation, 2018-03-07;15(1):72.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease
Authors: AW Clarke, L Poulton, D Shim, D Mabon, D Butt, M Pollard, V Pande, J Husten, J Lyons, C Tian, AG Doyle
MAbs, 2018-03-05;0(0):1-43.
Species: Human
Sample Types: Recombinant Protein
Applications: Surface Plasmon Resonance (SPR

Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury
Authors: S Wink, SW Hiemstra, S Huppelscho, JE Klip, B van de Wat
Arch. Toxicol., 2018-03-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

BTKCys481Serdrives ibrutinib resistance via ERK1/2, and protects BTKWild-TypeMYD88 mutated cells by a paracrine mechanism
Authors: JG Chen, X Liu, M Munshi, L Xu, N Tsakmaklis, MG Demos, A Kofides, ML Guerrera, GG Chan, CJ Patterson, KE Meid, J Gustine, T Dubeau, P Severns, JJ Castillo, ZR Hunter, J Wang, SJ Buhrlage, NS Gray, SP Treon, G Yang
Blood, 2018-03-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Class 1-selective histone deacetylase inhibitors enhance HIV latency reversal while preserving the activity of HDAC isoforms necessary for maximal HIV gene expression
Authors: TD Zaikos, MM Painter, NT Sebastian, VH Terry, KL Collins
J. Virol., 2018-02-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Angiokine Wisp-1 is increased in myocardial infarction and regulates cardiac endothelial signaling
Authors: LH Wright, DJ Herr, SS Brown, H Kasiganesa, DR Menick
JCI Insight, 2018-02-22;3(4):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

C/EBP? drives interactions between human MAIT cells and endothelial cells that are important for extravasation
Authors: CH Lee, HH Zhang, SP Singh, L Koo, J Kabat, H Tsang, TP Singh, JM Farber
Elife, 2018-02-22;7(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interactome analysis of transforming growth factor-?-activated kinase 1 inHelicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37
Authors: O Sokolova, T Kähne, K Bryan, M Naumann
Oncotarget, 2018-02-21;9(18):14366-14381.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

LAIR-1 shedding from human fibroblast-like synoviocytes in rheumatoid arthritis following TNF-? stimulation
Authors: Y Zhang, S Wang, H Dong, X Yi, J Zhang, X Liu, R Zhuang, Y Ding
Clin. Exp. Immunol., 2018-02-20;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Progesterone Inhibits Apoptosis in Fetal Membranes by Altering Expression of Both Pro- and Antiapoptotic Proteins
Authors: Y Wang, VM Abrahams, G Luo, NG Norwitz, VV Snegovskik, SW Ng, ER Norwitz
Reprod Sci, 2018-02-20;0(0):1933719118759.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models
Authors: A Lundin, L Delsing, M Clausen, P Ricchiuto, J Sanchez, A Sabirsh, M Ding, J Synnergren, H Zetterberg, G Brolén, R Hicks, A Herland, A Falk
Stem Cell Reports, 2018-02-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes
Authors: AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, EK Sims
Diabetologia, 2018-02-14;0(0):.
Species: Human, Mouse
Sample Types: Whole Cells
Applications: Cell Culture

Changes in the Anti-Allergic Activities of Sesame by Bioconversion
Authors: TD Jung, SI Choi, SH Choi, BY Cho, WS Sim, SJ Lee, SJ Park, DB Kim, YC Kim, JH Lee, OH Lee
Nutrients, 2018-02-14;10(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
Authors: MA Rapsomanik, XK Lun, S Woerner, M Laumanns, B Bodenmille, MR Martínez
Nat Commun, 2018-02-12;9(1):632.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Galectin-3 Plays an Important Role in Preterm Birth Caused by Dental Infection of Porphyromonas gingivalis
Authors: M Miyauchi, M Ao, H Furusho, C Chea, A Nagasaki, S Sakamoto, T Ando, T Inubushi, K Kozai, T Takata
Sci Rep, 2018-02-12;8(1):2867.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Filifactor alocis modulates human neutrophil antimicrobial functional responses
Authors: JS Edmisson, S Tian, CL Armstrong, A Vashishta, CK Klaes, I Miralda, E Jimenez-Fl, J Le, Q Wang, RJ Lamont, SM Uriarte
Cell. Microbiol., 2018-02-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts
Authors: M Armaka, C Ospelt, M Pasparakis, G Kollias
Nat Commun, 2018-02-12;9(1):618.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
Authors: W Klement, R Garbelli, E Zub, L Rossini, L Tassi, B Girard, M Blaquiere, F Bertaso, J Perroy, F de Bock, N Marchi
Neurobiol. Dis., 2018-02-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

Up-regulation of SFTPB expression and attenuation of acute lung injury by pulmonary epithelial cell-specific NAMPT knockdown
Authors: G Bi, L Wu, P Huang, S Islam, DP Heruth, LQ Zhang, DY Li, V Sampath, W Huang, BA Simon, RB Easley, SQ Ye
FASEB J., 2018-02-08;0(0):fj201701059R.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Virus-like infection induces human ? cell dedifferentiation
Authors: M Oshima, KP Knoch, M Diedisheim, A Petzold, P Cattan, M Bugliani, P Marchetti, P Choudhary, GC Huang, SR Bornstein, M Solimena, O Albagli-Cu, R Scharfmann
JCI Insight, 2018-02-08;3(3):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
Authors: L Chung, ET Orberg, AL Geis, JL Chan, K Fu, CED Shields, CM Dejea, P Fathi, J Chen, BB Finard, AJ Tam, FM McAllister, H Fan, X Wu, S Ganguly, A Lebid, P Metz, SW Van Meerbe, DL Huso, EC Wick, DM Pardoll, F Wan, S Wu, CL Sears, F Housseau
Cell Host Microbe, 2018-02-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ANKRD1 regulates innate immune responses against herpes simplex virus 1: A potential role in eczema herpeticum
Authors: L Bin, X Li, B Richers, JE Streib, JW Hu, P Taylor, DYM Leung
J. Allergy Clin. Immunol., 2018-01-31;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes
Authors: A Rutkowska, DR Shimshek, AW Sailer, KK Dev
Neuropharmacology, 2018-01-31;133(0):121-128.
Species: Human, Mouse, Rat
Sample Types: Whole Cells
Applications: Bioassay

RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature
Authors: WR Swindell, MA Beamer, MK Sarkar, S Loftus, J Fullmer, X Xing, NL Ward, LC Tsoi, MJ Kahlenberg, Y Liang, JE Gudjonsson
Front Immunol, 2018-01-29;9(0):80.
Species: Human
Sample Types: Whole Cells
Applications: Cell Culture

TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles
Authors: M Frank-Bert, DS Pisetsky, C Kolling, BA Michel, RE Gay, A Jüngel, S Gay
Front Immunol, 2018-01-29;9(0):28.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway
Authors: F Zhang, G Liu, D Li, C Wei, J Hao
J. Immunol., 2018-01-29;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
Sci Rep, 2018-01-24;8(1):1561.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock
Authors: TA Nakada, P Wacharasin, JA Russell, JH Boyd, E Nakada, SA Thair, T Shimada, KR Walley
J Innate Immun, 2018-01-16;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies
Authors: R Jalili, J Horecka, JR Swartz, RW Davis, HHJ Persson
Proc. Natl. Acad. Sci. U.S.A., 2018-01-16;0(0):.
Applications: Bioassay

Bridging pro-inflammatory signals, synaptic transmission and protection in spinal explants in vitro
Authors: M Medelin, V Giacco, A Aldinucci, G Castronovo, E Bonechi, A Sibilla, M Tanturli, M Torcia, L Ballerini, F Cozzolino, C Ballerini
Mol Brain, 2018-01-15;11(1):3.
Species: Mouse
Sample Types: Whole Tissue
Applications: Bioassay

NF-?B inducing kinase is a therapeutic target for systemic lupus erythematosus
Authors: HD Brightbill, E Suto, N Blaquiere, N Ramamoorth, S Sujatha-Bh, EB Gogol, GM Castanedo, BT Jackson, YC Kwon, S Haller, J Lesch, K Bents, C Everett, PB Kohli, S Linge, L Christian, K Barrett, A Jaochico, LM Berezhkovs, PW Fan, Z Modrusan, K Veliz, MJ Townsend, J DeVoss, AR Johnson, R Godemann, WP Lee, CD Austin, BS McKenzie, JA Hackney, JJ Crawford, ST Staben, MH Alaoui Ism, LC Wu, N Ghilardi
Nat Commun, 2018-01-12;9(1):179.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Role of thyroid transcription factor-1 in transcriptional regulation of heme oxygenase-1
Authors: B Jeong, HR Kim, NS Choi, BS Park, H Eom, JW Park, JG Kim, BJ Lee
Biochem. Biophys. Res. Commun., 2018-01-04;0(0):.
Species: Mouse, Rat
Sample Types: In Vivo, Whole Cells
Applications: Bioassay, In Vivo

EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells
Authors: YJ Choi, SJ Park, YS Park, HS Park, KM Yang, K Heo
PLoS ONE, 2018-01-03;13(1):e0190638.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RvD1 inhibits TNF?-induced c-Myc expression in normal intestinal epithelial cells and destabilizes hyper-expressed c-Myc in colon cancer cells
Authors: X Zhong, HN Lee, YJ Surh
Biochem. Biophys. Res. Commun., 2018-01-03;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells
Authors: X Zhang, Y Zhang, J Xu, H Wang, X Zheng, Y Lou, B Han
J Cancer, 2018-01-01;9(2):367-374.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Arsenite exposure potentiates apoptosis-inducing effects of tumor necrosis factor-alpha- through reactive oxygen species
Authors: P Singhirunn, B Moolmuang, K Lirdprapam, M Ruchirawat
J Toxicol Sci, 2018-01-01;43(2):159-169.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.
Authors: Michael J Workman, John P Gleeson, Elissa J Troisi, Hannah Q Estrada, S Jordan Kerns, Christopher D Hinojosa, Geraldine A Hamilton, Stephan R Targan, Clive N Svendsen, Robert J Barrett
Cellular and Molecular Gastroenterology and Hepatology, 2017-12-29;0(0):2352-345X.
Species: Human
Sample Types:
Applications: Bioassay

Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation
Authors: T Tanaka, Y Zhou, T Ozawa, R Okizono, A Banba, T Yamamura, E Oga, A Muraguchi, H Sakurai
J. Biol. Chem., 2017-12-18;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor
Authors: AT Holdbrooks, CM Britain, SL Bellis
J. Biol. Chem., 2017-12-12;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Long noncoding RNA NEAT1 promotes nasopharyngeal carcinoma progression through regulation of miR-124/NF-?B pathway
Authors: N Cheng, Y Guo
Onco Targets Ther, 2017-12-11;10(0):5843-5853.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Association of HMGB1 with oxidative stress markers and regulators in PDR
Authors: AM Abu El-Asr, K Alam, M Garcia-Ram, A Ahmad, MM Siddiquei, G Mohammad, A Mousa, G De Hertogh, G Opdenakker, R Simó
Mol. Vis., 2017-12-05;23(0):853-871.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Suberanilohydroxamic Acid as a Pharmacological Kruppel-Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis
Authors: Y Xu, S Xu, P Liu, M Koroleva, S Zhang, S Si, ZG Jin
J Am Heart Assoc, 2017-11-30;6(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Diosgenin, an Activator of 1,25D3-MARRS Receptor/ERp57, Attenuates the Effects of TNF-? by Causing ADAM10-Dependent Ectodomain Shedding of TNF Receptor 1
Authors: WS Yang, SY Moon, MJ Lee, EK Lee, SK Park
Cell. Physiol. Biochem., 2017-10-27;43(6):2434-2445.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-155 induction via TNF-? and IFN-? suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells
Authors: D Yee, KM Shah, MC Coles, TV Sharp, D Lagos
J. Biol. Chem., 2017-10-24;292(50):20683-20693.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFN-? and TNF-? synergism may provide a link between psoriasis and inflammatory atherogenesis
Authors: NN Mehta, HL Teague, WR Swindell, Y Baumer, NL Ward, X Xing, B Baugous, A Johnston, AA Joshi, J Silverman, DH Barnes, L Wolterink, RP Nair, PE Stuart, M Playford, JJ Voorhees, MK Sarkar, JT Elder, K Gallagher, SK Ganesh, JE Gudjonsson
Sci Rep, 2017-10-23;7(1):13831.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13
Authors: S Gogia, A Kelkar, C Zhang, KM Dayananda, S Neelamegha
Blood Adv, 2017-10-20;1(23):2063-2074.
Applications: Western Blot

Tumor necrosis factor ? decreases aquaporin 3 expression in intestinal epithelial cells through inhibition of constitutive transcription
Authors: MA Peplowski, AJ Vegso, V Iablokov, M Dicay, RS Zaheer, B Renaux, D Proud, MD Hollenberg, PL Beck, WK MacNaughto
Physiol Rep, 2017-10-16;5(19):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Healing of Preterm Ruptured Fetal Membranes
Authors: H Mogami, A Hari Kisho, Y Akgul, RA Word
Sci Rep, 2017-10-13;7(1):13139.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation
Authors: S Ebtehaj, EG Gruppen, M Parvizi, UJF Tietge, RPF Dullaart
Cardiovasc Diabetol, 2017-10-12;16(1):132.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HAT1 induces lung cancer cell apoptosis via up regulating Fas
Authors: N Han, L Shi, Q Guo, W Sun, Y Yu, L Yang, X Zhang, M Zhang
Oncotarget, 2017-09-23;8(52):89970-89977.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A type of human skin dendritic cell marked by CD5 is associated with the development of inflammatory skin disease
Authors: D Korenfeld, L Gorvel, A Munk, J Man, A Schaffer, T Tung, C Mann, E Klechevsky
JCI Insight, 2017-09-21;2(18):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of the Receptor Tyrosine Kinase AXL Restores Paclitaxel Chemosensitivity in Uterine Serous Cancer
Authors: ML Palisoul, JM Quinn, E Schepers, IS Hagemann, L Guo, K Reger, AR Hagemann, CK McCourt, PH Thaker, MA Powell, DG Mutch, KC Fuh
Mol. Cancer Ther., 2017-09-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
JCI Insight, 2017-09-07;2(17):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

CXorf48 is a potential therapeutic target for achieving treatment-free remission in CML patients
Authors: M Matsushita, K Ozawa, T Suzuki, M Nakamura, N Nakano, S Kanchi, D Ichikawa, E Matsuki, M Sakurai, D Karigane, H Kasahara, N Tsukamoto, T Shimizu, T Mori, H Nakajima, S Okamoto, Y Kawakami, Y Hattori
Blood Cancer J, 2017-09-01;7(9):e601.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
Authors: N Starc, D Ingo, A Conforti, V Rossella, L Tomao, A Pitisci, F De Mattia, I Brigida, M Algeri, M Montanari, G Palumbo, P Merli, P Rossi, A Aiuti, F Locatelli, ME Bernardo
Sci Rep, 2017-08-15;7(1):8153.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation
Authors: KA Bailey, FG Haj, SI Simon, AG Passerini
Sci Rep, 2017-08-15;7(1):8196.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Suppression of human arthritis synovial fibroblasts inflammation using dexamethasone-carbon nanotubes via increasing caveolin-dependent endocytosis and recovering mitochondrial membrane potential
Authors: YK Lee, SW Kim, JY Park, WC Kang, YJ Kang, D Khang
Int J Nanomedicine, 2017-08-10;12(0):5761-5779.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis
Authors: BK Hong, S You, SA Yoo, D Park, D Hwang, CS Cho, WU Kim
Exp. Mol. Med., 2017-08-04;49(8):e363.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-?-Induced NF-?B Activation
Authors: Z Wang, MY Li, C Mi, KS Wang, J Ma, X Jin
Int J Mol Sci, 2017-07-26;18(8):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis
Authors: E Couderc, F Morel, P Levillain, A Buffière-M, M Camus, C Paquier, C Bodet, JF Jégou, M Pohin, L Favot, M Garcia, V Huguier, J Mcheik, C Lacombe, H Yssel, G Guillet, FX Bernard, JC Lecron
PLoS ONE, 2017-07-14;12(7):e0181486.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching
Authors: R Ahmad, B Rah, D Bastola, P Dhawan, AB Singh
Sci Rep, 2017-07-11;7(1):5125.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1
Authors: J Yuzugulen, JA Douthwaite, EG Wood, IC Villar, NSA Patel, J Jegard, H Gaertner, I Rossitto-B, K Rose, O Hartley, PR Cutillas, A Ahluwalia, R Corder
Sci Rep, 2017-07-10;7(1):4956.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TNF?-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels
Authors: AE van der Wi, IMC Vogels, CJF van Noorde, I Klaassen, RO Schlingema
Invest. Ophthalmol. Vis. Sci., 2017-07-01;58(9):3496-3505.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Frontline Science: c-Myc regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection
Authors: R Connor, LD Jones, X Qiu, J Thakar, SB Maggirwar
J. Leukoc. Biol., 2017-06-29;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of benzazole compounds that induce HIV-1 transcription
Authors: JD Graci, D Michaels, G Chen, GM Schiralli, S Nodder, M Weetall, GM Karp, Z Gu, JM Colacino, AJ Henderson
PLoS ONE, 2017-06-28;12(6):e0179100.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-20 is triggered by TLR ligands and associates with disease activity in patients with rheumatoid arthritis
Authors: L Šenolt, K Prajzlerov, H Hulejová, B Šumová, M Filková, D Veigl, K Pavelka, J Vencovský
Cytokine, 2017-06-26;97(0):187-192.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Upregulation of circulating microRNA-134 in adult-onset Still's disease and its use as potential biomarker
Authors: TL Liao, YM Chen, CW Hsieh, HH Chen, HC Lee, WT Hung, KT Tang, DY Chen
Sci Rep, 2017-06-23;7(1):4214.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Metabolic Adaptation Establishes Disease Tolerance to Sepsis
Authors: S Weis, AR Carlos, MR Moita, S Singh, B Blankenhau, S Cardoso, R Larsen, S Rebelo, S Schäuble, L Del Barrio, G Mithieux, F Rajas, S Lindig, M Bauer, MP Soares
Cell, 2017-06-15;169(7):1263-1275.e14.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors
Authors: A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti
JCI Insight, 2017-06-15;2(12):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
Authors: JS Reyat, M Chimen, PJ Noy, J Szyroka, GE Rainger, MG Tomlinson
J. Immunol., 2017-06-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells
Authors: NT Hogan, MB Whalen, LK Stolze, NK Hadeli, MT Lam, JR Springstea, CK Glass, CE Romanoski
Elife, 2017-06-06;6(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells
Authors: R Santos, KC Vadodaria, BN Jaeger, A Mei, S Lefcochilo, APD Mendes, G Erikson, M Shokhirev, L Randolph-M, C Fredlender, S Dave, R Oefner, C Fitzpatric, M Pena, JJ Barron, M Ku, AM Denli, BE Kerman, P Charnay, JR Kelsoe, MC Marchetto, FH Gage
Stem Cell Reports, 2017-06-06;8(6):1757-1769.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Proinflammatory Cytokines IL-6 and TNF-? Increased Telomerase Activity through NF-?B/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells
Authors: SS Chung, Y Wu, Q Okobi, D Adekoya, M Atefi, O Clarke, P Dutta, JV Vadgama
Mediators Inflamm., 2017-06-06;2017(0):5958429.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

AAV-based dual-reporter circuit for monitoring cell signaling in living human cells
Authors: Z Zhang, Z Stickney, N Duong, K Curley, B Lu
J Biol Eng, 2017-06-05;11(0):18.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity
Authors: D Sagar, NP Singh, R Ginwala, X Huang, R Philip, M Nagarkatti, P Nagarkatti, K Neumann, J Ruland, AM Andrews, SH Ramirez, ZK Khan, P Jain
Sci Rep, 2017-06-02;7(1):2707.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The involvement and possible mechanism of pro-inflammatory tumor necrosis factor alpha (TNF-?) in thoracic ossification of the ligamentum flavum
Authors: C Zhang, Z Chen, X Meng, M Li, L Zhang, A Huang
PLoS ONE, 2017-06-02;12(6):e0178986.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Dendritic cells from rheumatoid arthritis patient peripheral blood induce Th17 cell differentiation via miR-363/Integrin ?v/TGF-? axis
Authors: F Pan, H Xiang, J Yan, L Hong, L Zhang, Y Liu, X Feng, C Cai
Scand. J. Immunol., 2017-06-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Identification of a small molecule that primes the type I interferon response to cytosolic DNA
Authors: S Khiar, M Lucas-Hour, S Nisole, N Smith, O Helynck, M Bourgine, C Ruffié, JP Herbeuval, H Munier-Leh, F Tangy, PO Vidalain
Sci Rep, 2017-05-31;7(1):2561.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

RalBP1 and p19-VHL play an oncogenic role, and p30-VHL plays a tumor suppressor role during the blebbishield emergency program
Authors: GG Jinesh, AM Kamat
Cell Death Discov, 2017-05-29;3(0):17023.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs)
Authors: K Kinnunen, N Piippo, S Loukovaara, M Hytti, K Kaarnirant, A Kauppinen
J Cell Commun Signal, 2017-05-25;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors
Authors: CH Lo, N Vunnam, AK Lewis, TL Chiu, BE Brummel, TM Schaaf, BD Grant, P Bawaskar, DD Thomas, JN Sachs
SLAS Discov, 2017-05-22;0(0):2472555217706.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Anti-Inflammatory Effects of OxPAPC Involve Endothelial Cell-Mediated Generation of LXA4.
Authors: Yunbo Ke, Noureddine Zebda, Olga Oskolkova, Taras Afonyushk, Evgeny Berdyshev, Yufeng Tian, Fanyong Meng, Nicolene Sarich, Valery N Bochkov, Ji Ming Wang, Anna A Birukova, Konstantin G Birukov
Circulation Research, 2017-05-18;0(0):1524-4571.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

TNF? promotes proliferation of human synovial MSCs while maintaining chondrogenic potential
Authors: M Shioda, T Muneta, K Tsuji, M Mizuno, K Komori, H Koga, I Sekiya
PLoS ONE, 2017-05-18;12(5):e0177771.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Ziziphus nummularia Inhibits Inflammation-Induced Atherogenic Phenotype of Human Aortic Smooth Muscle Cells
Authors: M Fardoun, T Al-Shehabi, A El-Yazbi, K Issa, F Zouein, D Maaliki, R Iratni, AH Eid
Oxid Med Cell Longev, 2017-05-15;2017(0):4134093.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The autocrine role of proteoglycan-4 (PRG4) in modulating osteoarthritic synoviocyte proliferation and expression of matrix degrading enzymes
Authors: A Alquraini, M Jamal, L Zhang, T Schmidt, GD Jay, KA Elsaid
Arthritis Res. Ther., 2017-05-08;19(1):89.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
Authors: Y Haim, M Blüher, D Konrad, N Goldstein, N Klöting, I Harman-Boe, B Kirshtein, D Ginsberg, T Tarnovscki, Y Gepner, I Shai, A Rudich
Mol Metab, 2017-05-06;6(7):725-736.
Species: Human
Sample Types: Whole Tissue
Applications: Bioassay

Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice
Authors: GW He, C Günther, V Thonn, YQ Yu, E Martini, B Buchen, MF Neurath, M Stürzl, C Becker
J. Exp. Med., 2017-05-05;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Apomorphine suppresses TNF-?-induced MMP-9 expression and cell invasion through inhibition of ERK/AP-1 signaling pathway in MCF-7 cells
Authors: YS Jung, SO Lee
Biochem. Biophys. Res. Commun., 2017-05-02;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

iTRAQ quantitative proteomic study in patients with thoracic ossification of the ligamentum flavum
Authors: B Wang, Z Chen, X Meng, M Li, X Yang, C Zhang
Biochem. Biophys. Res. Commun., 2017-04-26;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Adipogenic differentiation of MSC alters their immunomodulatory properties in a tissue-specific manner
Authors: H Munir, LS Ward, L Sheriff, S Kemble, S Nayar, F Barone, GB Nash, HM McGettrick
Stem Cells, 2017-04-24;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions
Authors: X Wang, R Wilkinson, K Kildey, J Potriquet, J Mulvenna, RJ Lobb, A Möller, N Cloonan, P Mukhopadhy, AJ Kassianos, H Healy
J Extracell Vesicles, 2017-04-21;6(1):1314073.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Augmented Serum Amyloid A1/2 Mediated by TNF-induced NF-?B in Human Serous Ovarian Epithelial Tumors
Authors: H Choi, RMC Ignacio, ES Lee, AJ Wilson, D Khabele, DS Son
Immune Netw, 2017-04-20;17(2):121-127.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis
Authors: H Al Faruque, JH Kang, SR Hwang, S Sung, MM Alam, KH Sa, EJ Nam, YR Byun, YM Kang
PLoS ONE, 2017-04-18;12(4):e0176110.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
Stem Cell Res Ther, 2017-04-17;8(1):79.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
Authors: KJ Chung, A Chatzigeor, M Economopou, R Garcia-Mar, VI Alexaki, I Mitroulis, M Nati, J Gebler, T Ziemssen, SE Goelz, J Phieler, JH Lim, KP Karalis, T Papayannop, M Blüher, G Hajishenga, T Chavakis
Nat. Immunol., 2017-04-17;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect
Authors: BS Patel, MJ Kugel, G Baehring, AJ Ammit
Pulm Pharmacol Ther, 2017-04-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Synovial cell death is regulated by TNF-?-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1?
Authors: JW Lee, J Lee, SH Um, EY Moon
Cell Death Dis, 2017-04-06;8(4):e2727.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps
Authors: BF Wang, PP Cao, ZC Wang, ZY Li, ZZ Wang, J Ma, B Liao, YK Deng, XB Long, K Xu, H Wang, H Wang, M Zeng, X Lu, Z Liu
Allergy, 2017-04-04;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Roflumilast N-oxide in Combination with Formoterol Enhances the Anti-inflammatory Effect of Dexamethasone in ASM Cells
Authors: Brijeshkumar S Patel
Am. J. Respir. Cell Mol. Biol, 2017-04-01;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Inhibition of 6-phosphofructo-2-kinase suppresses fibroblast-like synoviocytes- mediated synovial inflammation and joint destruction in rheumatoid arthritis
Authors: Y Zou, S Zeng, M Huang, Q Qiu, Y Xiao, M Shi, Z Zhan, L Liang, X Yang, H Xu
Br. J. Pharmacol, 2017-03-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
Authors: M Frank-Bert, M Trenkmann, K Klein, E Karouzakis, H Rehrauer, A Bratus, C Kolling, M Armaka, A Filer, BA Michel, RE Gay, CD Buckley, G Kollias, S Gay, C Ospelt
Nat Commun, 2017-03-23;8(0):14852.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology
Authors: M Silva, RK Fung, CB Donnelly, PA Videira, R Sackstein
J. Immunol, 2017-03-22;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

In�vitro model of cerebral ischemia by using brain microvascular endothelial cells derived from human induced pluripotent stem cells
Authors: Y Kokubu, T Yamaguchi, K Kawabata
Biochem. Biophys. Res. Commun, 2017-03-21;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Comprehensive proteome analysis of human skeletal muscle in cachexia and sarcopenia: A pilot study
Authors: HA Ebhardt, S Degen, V Tadini, A Schilb, N Johns, CA Greig, KC Fearon, R Aebersold, C Jacobi
J Cachexia Sarcopenia Muscle, 2017-03-15;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Autophagy Impairment by Helicobacter pylori-induced Methylation Silencing of MAP1LC3Av1 Promotes Gastric Carcinogenesis
Authors: JS Muhammad, S Nanjo, T Ando, S Yamashita, T Maekita, T Ushijima, Y Tabuchi, T Sugiyama
Int. J. Cancer, 2017-03-14;0(0):.
Species: Rat
Sample Types: Whole Cells
Applications: Bioassay

Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-? through up-regulation of TNF receptor 1 in lung cancer cells.
Authors: Bo Ra You, Bo Ram Han, Woo Hyun Park
Oncotarget, 2017-03-14;0(0):1949-2553.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?
Authors: JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, M Wittmann, M Stacey
Proc. Natl. Acad. Sci. U.S.A, 2017-03-13;114(13):E2748-E2757.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis
Authors: J Retzlaff, K Thamm, CC Ghosh, W Ziegler, H Haller, SM Parikh, S David
Sci Rep, 2017-03-09;7(0):44113.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A possible role for neutrophils in allergic rhinitis revealed after cellular subclassification
Authors: J Arebro, S Ekstedt, E Hjalmarsso, O Winqvist, S Kumlien Ge, LO Cardell
Sci Rep, 2017-03-08;7(0):43568.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-?B-Activating Factors through Direct Downregulation of IKK? and IKK?
Authors: MH Hancock, LM Hook, J Mitchell, JA Nelson
MBio, 2017-03-07;8(2):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
J. Immunol, 2017-03-06;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866
Authors: P Huang, MW Lee, K Sadrerafi, DP Heruth, LQ Zhang, D Maulik, SQ Ye
Drug Des Devel Ther, 2017-03-03;11(0):629-641.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

The role of indoleamine 2,3-dioxygenase-aryl hydrocarbon receptor pathway in the TLR4-induced tolerogenic phenotype in human DCs
Authors: F Salazar, D Awuah, OH Negm, F Shakib, AM Ghaemmagha
Sci Rep, 2017-03-03;7(0):43337.
Species: Complex Species Category
Sample Types: Plasma
Applications: Bioassay

Analytical ultracentrifugation with fluorescence detection system reveals differences in complex formation between recombinant human TNF and different biological TNF antagonists in various environments
Authors: E Krayukhina, M Noda, K Ishii, T Maruno, H Wakabayash, M Tada, T Suzuki, A Ishii-Wata, M Kato, S Uchiyama
MAbs, 2017-03-03;9(4):664-679.
Applications: Bioassay

Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques
Authors: SR DiNapoli, AM Ortiz, F Wu, K Matsuda, HL Twigg, VM Hirsch, K Knox, JM Brenchley
JCI Insight, 2017-02-23;2(4):e91214.
Species: Primate - Macaca mulatta (Rhesus Macaque)
Sample Types: Whole Cells
Applications: Bioassay

Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity
Authors: L Israel, Y Wang, K Bulek, E Della Mina, Z Zhang, V Pedergnana, M Chrabieh, NA Lemmens, V Sancho-Shi, M Descatoire, T Lasseau, E Israelsson, L Lorenzo, L Yun, A Belkadi, A Moran, LE Weisman, F Vandenesch, F Batteux, S Weller, M Levin, J Herberg, A Abhyankar, C Prando, Y Itan, WJB van Wamel, C Picard, L Abel, D Chaussabel, X Li, B Beutler, PD Arkwright, JL Casanova, A Puel
Cell, 2017-02-23;168(5):789-800.e10.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay, Cell Culture

Decitabine treatment sensitizes tumor cells to T-cell-mediated cytotoxicity in patients with myelodysplastic syndromes
Authors: Z Zhang, Q He, Y Tao, J Guo, F Xu, LY Wu, YS Zhao, D Wu, LY Zhou, JY Su, LX Song, C Xiao, X Li, CK Chang
Am J Transl Res, 2017-02-15;9(2):454-465.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

A double-negative feedback loop between EpCAM and ERK contributes to the regulation of epithelial-mesenchymal transition in cancer
Authors: NV Sankpal, TP Fleming, PK Sharma, HJ Wiedner, WE Gillanders
Oncogene, 2017-02-13;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Substance P enhances proliferation and paracrine potential of adipose-derived stem cells in�vitro
Authors: S Kim, J Piao, Y Son, HS Hong
Biochem. Biophys. Res. Commun, 2017-02-10;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells
Authors: M Tanaka, H Tashiro, B Omer, N Lapteva, J Ando, M Ngo, B Mehta, G Dotti, PR Kinchingto, AM Leen, C Rossig, CM Rooney
Clin. Cancer Res, 2017-02-09;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
Authors: S Zhu, Q Zhang, X Sun, HJ Zeh, MT Lotze, R Kang, D Tang
Cancer Res, 2017-01-27;0(0):.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

STAT3/NF-?B-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer
Authors: WY Kuo, L Hwu, CY Wu, JS Lee, CW Chang, RS Liu
Theranostics, 2017-01-15;7(3):647-663.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay

IFN type I and II induce BAFF secretion from human decidual stromal cells
Authors: AC Lundell, I Nordstr”m, K Andersson, C Lundqvist, E Telemo, S Nava, H Kaipe, A Rudin
Sci Rep, 2017-01-06;7(0):39904.
Species: Human
Sample Types: Whole Cells
Applications: Bioassay