Recombinant Human TNF-alpha Protein

Newer Version Available: 10291-TA
NEW
GMP Version Available: 210-GMP
GMP
A new TNF-alpha is available! The new protein is HEK293 expressed!

Carrier Free

Catalog # Availability Size / Price Qty
210-TA-02M/CF
210-TA-020/CF
210-TA-100/CF
210-TA-005/CF

With Carrier

Catalog # Availability Size / Price Qty
210-TA-020
210-TA-100
210-TA-005
Recombinant Human TNF-alpha Protein Bioactivity
2 Images
Product Details
Citations (674)
FAQs
Supplemental Products
Reviews (33)

Recombinant Human TNF-alpha Protein Summary

Product Specifications

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.10 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 221. The ED50 for this effect is 25-100 pg/mL.
The specific activity of Recombinant Human TNF-alpha is approximately 7.6 x 104 IU/μg, which is calibrated against human TNF-alpha WHO International Standard (NIBSC code: 88/786).   Specific activity is for reference purposes only and is not routinely tested.  
Source
E. coli-derived human TNF-alpha protein
Val77-Leu233, with and without an N-terminal Met
Accession #
N-terminal Sequence
Analysis
Met & Val77
Predicted Molecular Mass
17.5 kDa
SDS-PAGE
17 kDa, reducing conditions

Product Datasheets

210-TA (with carrier)

210-TA/CF (carrier free)

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

210-TA

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 0.1-1 mg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

210-TA/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS. *Small pack size (5 & 20 µg) is supplied as a 0.2 µm filtered solution in PBS. 
Reconstitution Reconstitute at 0.1-1 mg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (5 & 20 µg) is shipped with dry ice or equivalent. Upon receipt, store it immediately at -20 to -70 °C.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Images

Bioactivity Recombinant Human TNF-alpha Protein Bioactivity View Larger

Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 25‑100 pg/mL.

SDS-PAGE Recombinant Human TNF-alpha Protein SDS-PAGE View Larger

1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: TNF-alpha

Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (1, 2). Human TNF-alpha consisits of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD) (3). Within the ECD, human TNF-alpha shares 97% aa sequence identity with rhesus and 71%-92% with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-alpha. TNF-alpha is produced by a wide variety of immune, epithelial, endothelial, and tumor cells (1, 2). TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface (4). Cell surface TNF-alpha can induce the lysis of neighboring tumor cells and virus infected cells, and it can generate its own downstream cell signaling following ligation by soluble TNFR I (2, 5). Shedding of membrane bound TNF-alpha by TACE/ADAM17 releases the bioactive cytokine, a 55 kDa soluble trimer of the TNF-alpha extracellular domain (6-8). TNF-alpha binds the ubiquitous 55-60 kDa TNF RI (9, 10) and the hematopoietic cell-restricted 80 kDa TNF RII (11, 12), both of which are also expressed as homotrimers (1, 2, 13). Both type I and type II receptors bind TNF-alpha with comparable affinity (14), although only TNF RI contains a cytoplasmic death domain which triggers the activation of apoptosis. Soluble forms of both types of receptors are released and can neutralize the biological activity of TNF-alpha (15).

References
  1. Zelova, H. and J. Hosek (2013) Inflamm. Res. 62:641.
  2. Juhasz, K. et al. (2013) Expert Rev. Clin. Immunol. 9:335.
  3. Pennica, D. et al. (1984) Nature 312:724.
  4. Tang, P. et al. (1996) Biochemistry 35:8216.
  5. Perez, C. et al. (1990) Cell 63:251.
  6. Black, R.A. et al. (1997) Nature 385:729.
  7. Moss, M.L. et al. (1997) Nature 385:733.
  8. Gearing, A.J.H. et al. (1994) Nature 370:555.
  9. Schall, T.J. et al. (1990) Cell 61:361.
  10. Loetscher, H. et al. (1990) Cell 61:351.
  11. Dembic, Z. et al. (1990) Cytokine 2:231.
  12. Smith, C.A. et al. (1990) Science 248:1019.
  13. Loetscher, H. et al. (1991) J. Biol. Chem. 266:18324.
  14. Pinckard, J.K. et al. (1997) J. Biol. Chem. 272:10784.
  15. Engelmann, H. et al. (1990) J. Biol. Chem. 265:1531.
Long Name
Tumor Necrosis Factor alpha
Entrez Gene IDs
7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 102139631 (Cynomolgus Monkey); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
Alternate Names
APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFG1F; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha

Citations for Recombinant Human TNF-alpha Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

674 Citations: Showing 1 - 10
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  1. Calcium-dependent cytosolic phospholipase A2 activation is implicated in neuroinflammation and oxidative stress associated with ApoE4
    Authors: S Wang, B Li, V Solomon, A Fonteh, SI Rapoport, DA Bennett, Z Arvanitaki, HC Chui, C Miller, PM Sullivan, HY Wang, HN Yassine
    Molecular Neurodegeneration, 2021;16(1):26.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. MKL1 cooperates with p38MAPK to promote vascular senescence, inflammation, and abdominal aortic aneurysm
    Authors: P Gao, P Gao, J Zhao, S Shan, W Luo, OJ Slivano, W Zhang, A Tabuchi, SA LeMaire, L Maegdefess, YH Shen, JM Miano, HA Singer, X Long
    Redox Biology, 2021;41(0):101903.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  3. Pharmacological Insights Into Safety and Efficacy Determinants for the Development of Adenosine Receptor Biased Agonists in the Treatment of Heart Failure
    Authors: P Rueda, J Merlin, S Chimenti, M Feletou, J Paysant, PJ White, A Christopou, PM Sexton, RJ Summers, WN Charman, LT May, CJ Langmead
    Frontiers in Pharmacology, 2021;12(0):628060.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  4. Lung macrophages drive mucus production and steroid-resistant inflammation in chronic bronchitis
    Authors: K Andelid, K Öst, A Andersson, E Mohamed, Z Jevnikar, LEGW Vanfletere, M Göransson
    Respiratory Research, 2021;22(1):172.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Transdifferentiation of Human Fibroblasts into Skeletal Muscle Cells: Optimization and Assembly into Engineered Tissue Constructs through Biological Ligands
    Authors: KMA Abdel-Raou, R Rezgui, C Stefanini, JCM Teo, N Christofor
    Biology, 2021;10(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  6. LL-37-mediated activation of host receptors is critical for defense against group A streptococcal infection
    Authors: D Biswas, P Ambalavana, M Ravins, A Anand, A Sharma, KXZ Lim, RYM Tan, HY Lim, A Sol, G Bachrach, V Angeli, E Hanski
    Cell Reports, 2021;34(9):108766.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  7. Transcriptome Landscape of Epithelial to Mesenchymal Transition of Human Stem Cell-Derived RPE
    Authors: SR Sripathi, MW Hu, MM Liu, J Wan, J Cheng, Y Duan, JL Mertz, KJ Wahlin, J Maruotti, CA Berlinicke, J Qian, DJ Zack
    Investigative Ophthalmology & Visual Science, 2021;62(4):1.
    Species: Human
    Sample Types: Tissue Culture
    Applications: Tissue Culture
  8. Cellular Importin-&alpha3 Expression Dynamics in the Lung Regulate Antiviral Response Pathways against Influenza A Virus Infection
    Authors: S Thiele, S Stanelle-B, S Beck, NM Kouassi, M Zickler, M Müller, B Tuku, P Resa-Infan, D van Riel, M Alawi, T Günther, F Rother, S Hügel, S Reimering, A McHardy, A Grundhoff, W Brune, A Osterhaus, M Bader, E Hartmann, G Gabriel
    Cell Rep, 2020;31(3):107549.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Urinary cMet as a prognostic marker in immunoglobulin A nephropathy
    Authors: JN An, L Li, J Lee, SS Yu, JH Kim, J Lee, YC Kim, DK Kim, YK Oh, CS Lim, YS Kim, S Kim, SH Yang, JP Lee
    J. Cell. Mol. Med., 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  10. MIP-1&alpha Expression Induced by Co-Stimulation of Human Monocytic Cells with Palmitate and TNF-&alpha Involves the TLR4-IRF3 Pathway and Is Amplified by Oxidative Stress
    Authors: S Sindhu, N Akhter, A Wilson, R Thomas, H Arefanian, A Al Madhoun, F Al-Mulla, R Ahmad
    Cells, 2020;9(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Association of tricellulin expression with poor colorectal cancer prognosis and metastasis
    Authors: JX Zhang, MB Qin, Z Ye, P Peng, SM Li, Q Song, L Lin, SQ Liu, LH Xie, Y Zhu, JA Huang
    Oncology reports, 2020;44(5):2174-2184.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  12. Acadesine suppresses TNF-&alpha induced complement component 3 (C3), in retinal pigment epithelial (RPE) cells
    Authors: NE Efstathiou, GA Moustafa, DE Maidana, EK Konstantin, S Notomi, PRT Barbisan, CD Georgakopo, JW Miller, DG Vavvas
    PLoS ONE, 2020;15(12):e0244307.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  13. Monocyte chemoattractant protein?1 promotes the proliferation, migration and differentiation potential of fibroblast?like synoviocytes via the PI3K/P38 cellular signaling pathway
    Authors: X Tong, H Zeng, P Gu, K Wang, H Zhang, X Lin
    Mol Med Rep, 2020;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Cell Culture
  14. Tumor necrosis factor-&alpha regulates skeletal myogenesis by inhibiting SP1 interaction with cis-acting regulatory elements within the Fbxl2 gene promoter
    Authors: ME O'Brien, J Londino, M McGinnis, N Weathingto, J Adair, T Suber, V Kagan, K Chen, C Zou, B Chen, J Bon, RK Mallampall
    Mol. Cell. Biol., 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
  15. Group V secreted phospholipase A2 plays a protective role against aortic dissection
    Authors: K Watanabe, Y Taketomi, Y Miki, K Kugiyama, M Murakami
    J. Biol. Chem., 2020;295(30):10092-10111.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  16. Synergistic activation of NF-&kappaB by TNFAIP3 (A20) reduction and UBE2L3 (UBCH7) augment that synergistically elevate lupus risk
    Authors: T Kim, SC Bae, C Kang
    Arthritis Res. Ther., 2020;22(1):93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  17. M1-like macrophages are potent producers of anti-viral interferons and M1-associated marker-positive lung macrophages are decreased during rhinovirus-induced asthma exacerbations
    Authors: A Nikonova, M Khaitov, DJ Jackson, S Traub, MB Trujillo-T, DA Kudlay, AS Dvornikov, A Del-Rosari, R Valenta, LA Stanciu, R Khaitov, SL Johnston
    EBioMedicine, 2020;54(0):102734.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  18. Ultrasensitive digital quantification of cytokines and bacteria predicts septic shock outcomes
    Authors: MF Abas?yan?k, K Wolfe, H Van Phan, J Lin, B Laxman, SR White, PA Verhoef, GM Mutlu, B Patel, S Tay
    Nat Commun, 2020;11(1):2607.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  19. Beclin 1 functions as a negative modulator of MLKL oligomerisation by integrating into the necrosome complex
    Authors: J Seo, D Seong, YW Nam, CH Hwang, SR Lee, CS Lee, Y Jin, HW Lee, DB Oh, P Vandenabee, J Song
    Cell Death Differ., 2020;0(0):.
    Applications: Cell Culture
  20. Preclinical validation of therapeutic targets predicted by tensor factorization on heterogeneous graphs
    Authors: S Paliwal, A de Giorgio, D Neil, JB Michel, AM Lacoste
    Sci Rep, 2020;10(1):18250.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  21. Inhibiting Airway Smooth Muscle Contraction Using Pitavastatin: A Role for the Mevalonate Pathway in Regulating Cytoskeletal Proteins
    Authors: RA Lu, AA Zeki, S Ram-Mohan, N Nguyen, Y Bai, K Chmiel, S Pecic, X Ai, R Krishnan, CC Ghosh
    Front Pharmacol, 2020;11(0):469.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  22. Baicalin Inhibits Cell Proliferation and Inflammatory Cytokines Induced by Tumor Necrosis Factor &alpha (TNF-&alpha) in Human Immortalized Keratinocytes (HaCaT) Human Keratinocytes by Inhibiting the STAT3/Nuclear Factor kappa B (NF-?B) Signaling Pathway
    Authors: X Wu, X Deng, J Wang, Q Li
    Med. Sci. Monit., 2020;26(0):e919392.
    Species: Human
    Sample Types: Whole Cells
  23. Characterization of the interleukin-17 effect on articular cartilage in a translational model: an explorative study
    Authors: D Sinkeviciu, A Aspberg, Y He, AC Bay-Jensen, P Önnerfjord
    BMC Rheumatol, 2020;4(0):30.
    Species: Bovine
    Sample Types: Whole Tissue
    Applications: Bioassay
  24. Increasing the Medium Osmolarity Reduces the Inflammatory Status of Human OA Chondrocytes and Increases Their Responsiveness to GDF-5
    Authors: T Mang, S Lindemann, A Gigout
    Int J Mol Sci, 2020;21(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  25. Fluorofenidone Alleviates Renal Fibrosis by Inhibiting Necroptosis Through RIPK3/MLKL Pathway
    Authors: Q Dai, Y Zhang, X Liao, Y Jiang, X Lv, X Yuan, J Meng, Y Xie, Z Peng, Q Yuan, L Tao, L Huang
    Frontiers in Pharmacology, 2020;11(0):534775.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  26. Diminished toll-like receptor response in febrile infection-related epilepsy syndrome (FIRES)
    Authors: MY Hsieh, JJ Lin, SH Hsia, JL Huang, KW Yeh, KW Chang, WI Lee
    Biomed J, 2020;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  27. Aberrant expression of NKL homeobox genes HMX2 and HMX3 interferes with cell differentiation in acute myeloid leukemia
    Authors: S Nagel, C Pommerenke, C Meyer, RAF MacLeod, HG Drexler
    PLoS ONE, 2020;15(10):e0240120.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  28. Relative Deficiency of Anti-Inflammatory N-Acylethanolamines Compared to Prostaglandins in Oral Lichen Planus
    Authors: L Rankin, S Gouveia-Fi, KP Danielsson, CJ Fowler
    Biomedicines, 2020;8(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  29. LPS Induces GM-CSF Production by Breast Cancer MDA-MB-231 Cells via Long-Chain Acyl-CoA Synthetase 1
    Authors: F Al-Rashed, R Thomas, A Al-Roub, F Al-Mulla, R Ahmad
    Molecules, 2020;25(20):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  30. CD4 T-cell immune stimulation of HER2?+?breast cancer cells alters response to trastuzumab in vitro
    Authors: PN Song, A Mansur, KJ Dugger, TR Davis, G Howard, TE Yankeelov, AG Sorace
    Cancer Cell International, 2020;20(1):544.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  31. JAK inhibition reduces SARS-CoV-2 liver infectivity and modulates inflammatory responses to reduce morbidity and mortality
    Authors: J Stebbing, G Sánchez Ni, M Falcone, S Youhanna, P Richardson, S Ottaviani, JX Shen, C Sommerauer, G Tiseo, L Ghiadoni, A Virdis, F Monzani, LR Rizos, F Forfori, A Avendaño-C, S De Marco, L Carrozzi, F Lena, PM Sánchez-Ju, LG Lacerenza, N Cesira, D Caldevilla, A Perrella, L Niccoli, LS Méndez, D Matarrese, D Goletti, YJ Tan, V Monteil, G Dranitsari, F Cantini, A Farcomeni, S Dutta, SK Burley, H Zhang, M Pistello, W Li, M Mas Romero, F Andrés Pre, RS Simón-Tale, R García-Mol, C Kutter, JH Felce, ZF Nizami, AG Miklosi, JM Penninger, F Menichetti, A Mirazimi, P Abizanda, VM Lauschke
    Sci Adv, 2020;0(0):.
    Species: Human
    Sample Types: Spheroid
    Applications: Spheroid Culture
  32. Caspase-1-dependent inflammasomes mediate photoreceptor cell death in photo-oxidative damage-induced retinal degeneration
    Authors: Y Wooff, N Fernando, JHC Wong, C Dietrich, R Aggio-Bruc, JA Chu-Tan, AAB Robertson, SL Doyle, SM Man, R Natoli
    Sci Rep, 2020;10(1):2263.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  33. The Expressions of TSLP, IL-33, and IL-17A in Monocyte Derived Dendritic Cells from Asthma and COPD Patients are Related to Epithelial-Macrophage Interactions
    Authors: M Paplinska-, P Misiukiewi, M Proboszcz, P Nejman-Gry, K Gorska, R Krenke
    Cells, 2020;9(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  34. Stearic Acid and TNF-&alpha Co-Operatively Potentiate MIP-1&alpha Production in Monocytic Cells via MyD88 Independent TLR4/TBK/IRF3 Signaling Pathway
    Authors: S Kochumon, H Arefanian, R Azim, S Shenouda, T Jacob, N Abu Khalaf, F Al-Rashed, A Hasan, S Sindhu, F Al-Mulla, R Ahmad
    Biomedicines, 2020;8(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  35. &beta-Catenin Regulates Wound Healing and IL-6 Expression in Activated Human Astrocytes
    Authors: VV Edara, S Nooka, J Proulx, S Stacy, A Ghorpade, K Borgmann
    Biomedicines, 2020;8(11):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  36. The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG
    Authors: K Landgraf, N Klöting, M Gericke, N Maixner, E Guiu-Jurad, M Scholz, AV Witte, F Beyer, JT Schwartze, M Lacher, A Villringer, P Kovacs, A Rudich, M Blüher, W Kiess, A Körner
    Cell Rep, 2020;33(3):108295.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Neutrophil GM-CSF receptor dynamics in acute lung injury
    Authors: S De Alessan, GJ Ferguson, AJ Dodd, JK Juss, A Devaprasad, S Piper, O Wyatt, H Killick, DJ Corkill, ES Cohen, A Pandit, TRDJ Radstake, R Simmonds, AM Condliffe, MA Sleeman, AS Cowburn, DK Finch, ER Chilvers
    J. Leukoc. Biol., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Long intergenic non-coding RNAs regulate human lung fibroblast function: Implications for idiopathic pulmonary fibrosis
    Authors: MR Hadjichara, BT Roux, E Csomor, CA Feghali-Bo, LA Murray, DL Clarke, MA Lindsay
    Sci Rep, 2019;9(1):6020.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  39. Xanthatin inhibits STAT3 and NF-?B signalling by covalently binding to JAK and IKK kinases
    Authors: M Liu, CQ Xiao, MW Sun, MJ Tan, LH Hu, Q Yu
    J. Cell. Mol. Med., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Rifamycin SV exhibits strong anti-inflammatory in�vitro activity through pregnane X receptor stimulation and NF?B inhibition
    Authors: C Rosette, FJ Agan, N Rosette, L Moro, A Mazzetti, C Hassan, M Gerloni
    Drug Metab. Pharmacokinet., 2019;34(3):172-180.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Characterization of a New Member of Alphacoronavirus with Unique Genomic Features in Rhinolophus Bats
    Authors: N Wang, C Luo, H Liu, X Yang, B Hu, W Zhang, B Li, Y Zhu, G Zhu, X Shen, C Peng, Z Shi
    Viruses, 2019;11(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Langerhans Cells Sense Staphylococcus aureus Wall Teichoic Acid through Langerin To Induce Inflammatory Responses
    Authors: R van Dalen, JS De La Cruz, M Rumpret, FF Fuchsberge, NH van Teijli, J Hanske, C Rademacher, TBH Geijtenbee, JAG van Strijp, C Weidenmaie, A Peschel, DH Kaplan, NM van Sorge
    MBio, 2019;10(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  43. A Novel TNF-?-Targeting Aptamer for TNF-?-Mediated Acute Lung Injury and Acute Liver Failure
    Authors: WY Lai, JW Wang, BT Huang, EP Lin, PC Yang
    Theranostics, 2019;9(6):1741-1751.
    Species: Human
    Sample Types: DNA
    Applications: Bioassay
  44. Differential modulation of CXCL8 versus CXCL10, by cytokines, PPAR-gamma, or PPAR-alpha agonists, in primary cells from Graves' disease and ophthalmopathy
    Authors: SM Ferrari, F Ragusa, SR Paparo, F Nasini, M Nardi, SS Franceschi, P Fallahi, A Antonelli
    Autoimmun Rev, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Extrinsic or Intrinsic Apoptosis by Curcumin and Light: Still a Mystery
    Authors: V Laubach, R Kaufmann, A Bernd, S Kippenberg, N Zöller
    Int J Mol Sci, 2019;20(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  46. Heterogeneous GM-CSF signaling in macrophages is associated with control of Mycobacterium tuberculosis
    Authors: BD Bryson, TR Rosebrock, FG Tafesse, CY Itoh, A Nibasumba, GH Babunovic, B Corleis, C Martin, C Keegan, P Andrade, S Realegeno, D Kwon, RL Modlin, SM Fortune
    Nat Commun, 2019;10(1):2329.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Low concentration flufenamic acid enhances osteogenic differentiation of mesenchymal stem cells and suppresses bone loss by inhibition of the NF-κB signaling pathway
    Authors: X Liu, Z Li, H Liu, Y Zhu, D Xia, S Wang, R Gu, W Wu, P Zhang, Y Liu, Y Zhou
    Stem Cell Res Ther, 2019;10(1):213.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  48. Type 1-programmed dendritic cells drive antigen-specific latency reversal and immune elimination of persistent HIV-1
    Authors: J Kristoff, ML Palma, TM Garcia-Bat, C Shen, N Sluis-Crem, P Gupta, CR Rinaldo, RB Mailliard
    EBioMedicine, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  49. CRISPR/Cas9 Screens Reveal Multiple Layers of B cell CD40 Regulation
    Authors: C Jiang, SJ Trudeau, TC Cheong, R Guo, M Teng, LW Wang, Z Wang, C Pighi, C Gautier-Co, Y Ma, S Jiang, C Wang, B Zhao, L Paillard, JG Doench, R Chiarle, BE Gewurz
    Cell Rep, 2019;28(5):1307-1322.e8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  50. The P-selectin and PSGL-1 axis accelerates atherosclerosis via activation of dendritic cells by the TLR4 signaling pathway
    Authors: Z Ye, L Zhong, S Zhu, Y Wang, J Zheng, S Wang, J Zhang, R Huang
    Cell Death Dis, 2019;10(7):507.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Cancer-associated fibroblast-derived Gremlin 1 promotes breast cancer progression
    Authors: J Ren, M Smid, J Iaria, DCF Salvatori, H van Dam, HJ Zhu, JWM Martens, P Ten Dijke
    Breast Cancer Res., 2019;21(1):109.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Effect of Ionizing Radiation on Human EA.hy926 Endothelial Cells under Inflammatory Conditions and Their Interactions with A549 Tumour Cells
    Authors: S Schröder, S Broese, J Baake, D Juer beta, S Kriesen, G Hildebrand, K Manda
    J Immunol Res, 2019;2019(0):9645481.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  53. Progenitor-derived human endothelial cells evade alloimmunity by CRISPR/Cas9-mediated complete ablation of MHC expression
    Authors: J Merola, M Reschke, RW Pierce, L Qin, S Spindler, T Baltazar, TD Manes, F Lopez-Gira, G Li, LG Bracaglia, C Xie, N Kirkiles-S, WM Saltzman, GT Tietjen, G Tellides, JS Pober
    JCI Insight, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  54. Denisovan, modern human and mouse TNFAIP3 alleles tune A20 phosphorylation and immunity
    Authors: NW Zammit, OM Siggs, PE Gray, K Horikawa, DB Langley, SN Walters, SR Daley, C Loetsch, J Warren, JY Yap, D Cultrone, A Russell, EK Malle, JE Villanueva, MJ Cowley, V Gayevskiy, ME Dinger, R Brink, D Zahra, G Chaudhri, G Karupiah, B Whittle, C Roots, E Bertram, M Yamada, Y Jeelall, A Enders, BE Clifton, PD Mabbitt, CJ Jackson, SR Watson, CN Jenne, LL Lanier, T Wiltshire, MH Spitzer, GP Nolan, F Schmitz, A Aderem, BT Porebski, AM Buckle, DW Abbott, JB Ziegler, ME Craig, P Benitez-Ag, J Teo, SG Tangye, C King, M Wong, MP Cox, W Phung, J Tang, W Sandoval, IE Wertz, D Christ, CC Goodnow, ST Grey
    Nat. Immunol., 2019;20(10):1299-1310.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Glucocorticoid-dependent expression of IAP participates in the protection against TNF-mediated cytotoxicity in MCF7 cells
    Authors: IB Mitre-Agui, T Barrios-Ga, VM Ruiz-Lopez, AJ Cabrera-Qu, NR Mejia-Domi, JL Ventura-Ga, D Moreno-Mit, A Aranda-Gut, J Mejia-Rang, AR Escalona-G, Y Chavarri-G, A Leon-Del-R, A Zentella-D
    BMC Cancer, 2019;19(1):356.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Synthesis and Biological Evaluation of Fangchinoline Derivatives as Anti-Inflammatory Agents through Inactivation of Inflammasome
    Authors: T Liu, Q Zeng, X Zhao, W Wei, Y Li, H Deng, D Song
    Molecules, 2019;24(6):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  57. CD44 Assists the Topical Anti-Psoriatic Efficacy of Curcumin-Loaded Hyaluronan-Modified Ethosomes: A New Strategy for Clustering Drug in Inflammatory Skin
    Authors: Y Zhang, Q Xia, Y Li, Z He, Z Li, T Guo, Z Wu, N Feng
    Theranostics, 2019;9(1):48-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Differential expression and regulation of the non-integrin 37/67-kDa laminin receptor on peripheral blood leukocytes of healthy individuals and patients with rheumatoid arthritis
    Authors: BA Kane, H An, P Rajasekari, HP McNeil, K Bryant, N Tedla
    Sci Rep, 2019;9(1):1149.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  59. hCMV-Mediated Immune Escape Mechanisms Favor Pathogen Growth and Disturb the Immune Privilege of the Eye
    Authors: K Spekker-Bo, CM Ufermann, M Maywald, A Zimmermann, A Domröse, C Woite, W Däubener, SK Eller
    Int J Mol Sci, 2019;20(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Anti-Allergic and Anti-Inflammatory Effects of Kuwanon G and Morusin on MC/9 Mast Cells and HaCaT Keratinocytes
    Authors: SE Jin, H Ha, HK Shin, CS Seo
    Molecules, 2019;24(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Autoimmune rheumatic disease IgG has differential effects upon neutrophil integrin activation that is modulated by the endothelium
    Authors: AA Khawaja, C Pericleous, VM Ripoll, JC Porter, IP Giles
    Sci Rep, 2019;9(1):1283.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Ornithine decarboxylase antizyme inhibitor 2 (AZIN2) is a signature of secretory phenotype and independent predictor of adverse prognosis in colorectal cancer
    Authors: T Kaprio, T Rasila, J Hagström, H Mustonen, P Lankila, C Haglund, LC Andersson
    PLoS ONE, 2019;14(2):e0211564.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  63. The inhibitor apoptosis protein antagonist Debio 1143 Is an attractive HIV-1 latency reversal candidate
    Authors: M Bobardt, J Kuo, U Chatterji, S Chanda, SJ Little, N Wiedemann, G Vuagniaux, PA Gallay
    PLoS ONE, 2019;14(2):e0211746.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Expression of connective tissue growth factor as a prognostic indicator and its possible involvement in the aggressive properties of epithelial ovarian carcinoma
    Authors: A Shimbo, H Kajiyama, S Tamauchi, N Yoshikawa, Y Ikeda, K Nishino, S Suzuki, K Niimi, J Sakata, F Kikkawa
    Oncol. Rep., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Cortistatin binds to TNF-? receptors and protects against osteoarthritis
    Authors: Y Zhao, Y Li, R Qu, X Chen, W Wang, C Qiu, B Liu, X Pan, L Liu, K Vasilev, J Hayball, S Dong, W Li
    EBioMedicine, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Inhibition of PTGS1 promotes osteogenic differentiation of adipose-derived stem cells by suppressing NF-kB signaling
    Authors: Y Wang, Y Liu, M Zhang, L Lv, X Zhang, P Zhang, Y Zhou
    Stem Cell Res Ther, 2019;10(1):57.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Targeted Disruption of HLA Genes via CRISPR-Cas9 Generates iPSCs with Enhanced Immune Compatibility
    Authors: H Xu, B Wang, M Ono, A Kagita, K Fujii, N Sasakawa, T Ueda, P Gee, M Nishikawa, M Nomura, F Kitaoka, T Takahashi, K Okita, Y Yoshida, S Kaneko, A Hotta
    Cell Stem Cell, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  68. CCL27/CCL28-CCR10 CHEMOKINE SIGNALING MEDIATES MIGRATION OF LYMPHATIC ENDOTHELIAL CELLS
    Authors: T Karnezis, R Farnsworth, NC Harris, SP Williams, C Caesar, DJ Byrne, P Herle, ML Macheda, R Shayan, YF Zhang, S Yazar, SJ Takouridis, C Gerard, S Fox, MG Achen, SA Stacker
    Cancer Res., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  69. Constructive approach for synthesis of a functional IgG using a reconstituted cell-free protein synthesis system
    Authors: S Murakami, R Matsumoto, T Kanamori
    Sci Rep, 2019;9(1):671.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: ELISA (Capture)
  70. Trimethylamine N-oxide promotes tissue factor expression and activity in vascular endothelial cells: A new link between trimethylamine N-oxide and atherosclerotic thrombosis
    Authors: X Cheng, X Qiu, Y Liu, C Yuan, X Yang
    Thromb. Res., 2019;177(0):110-116.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  71. TGF-?1/p65/MAT2A pathway regulates liver fibrogenesis via intracellular SAM
    Authors: K Wang, S Fang, Q Liu, J Gao, X Wang, H Zhu, Z Zhu, F Ji, J Wu, Y Ma, L Hu, X Shen, D Gao, J Zhu, P Liu, H Zhou
    EBioMedicine, 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Intravascular heavy chain-modification of hyaluronan during endotoxic shock
    Authors: K Ni, A Gill, D Cao, K Koike, KS Schweitzer, S Garantziot, I Petrache
    Biochem Biophys Rep, 2019;17(0):114-121.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  73. Physicochemical characterization and phase I study of CMAB008, an infliximab biosimilar produced by a different expression system
    Authors: Q An, Y Zheng, Y Zhao, T Liu, H Guo, D Zhang, W Qian, H Wang, Y Guo, S Hou, J Li
    Drug Des Devel Ther, 2019;13(0):791-805.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Involvement of the Dectin-1 Receptor upon the Effector Mechanisms of Human Phagocytic Cells against Paracoccidioides brasiliensis
    Authors: JC de Quaglia, AM Della Cole, TP Gardizani, GG Romagnoli, R Kaneno, LA Dias-Melic
    J Immunol Res, 2019;2019(0):1529189.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  75. The Possible Role of Neutrophils in the Induction of Osteoclastogenesis
    Authors: CGJ Moonen, TJ de Vries, P Rijkschroe, PE Poubelle, EA Nicu, BG Loos
    J Immunol Res, 2019;2019(0):8672604.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  76. TAK1 suppresses RIPK1-dependent cell death and is associated with disease progression in melanoma
    Authors: B Podder, C Guttà, J Rožanc, E Gerlach, M Feoktistov, D Panayotova, LG Alexopoulo, M Leverkus, M Rehm
    Cell Death Differ., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Melatonin Rescued Reactive Oxygen Species-Impaired Osteogenesis of Human Bone Marrow Mesenchymal Stem Cells in the Presence of Tumor Necrosis Factor-Alpha
    Authors: X Qiu, X Wang, J Qiu, Y Zhu, T Liang, B Gao, Z Wu, C Lian, Y Peng, A Liang, P Su, D Huang
    Stem Cells Int, 2019;2019(0):6403967.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  78. NF-kappaB-mediated inhibition of microRNA-149-5p regulates Chitinase-3-like 1 expression in human airway epithelial cells
    Authors: K Hübner, D Karwelat, E Pietsch, I Beinborn, S Winterberg, K Bedenbende, BJ Benedikter, B Schmeck, E Vollmeiste
    Cell. Signal., 2019;67(0):109498.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Down-regulation of the islet-specific zinc transporter-8 (ZnT8) protects human insulinoma cells against inflammatory stress
    Authors: C Merriman, D Fu
    J. Biol. Chem., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Anti-inflammatory mechanisms of the novel cytokine interleukin-38 in allergic asthma
    Authors: X Sun, T Hou, E Cheung, TN Iu, VW Tam, IM Chu, MS Tsang, PK Chan, CW Lam, CK Wong
    Cell. Mol. Immunol., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Hydrogel based protein biochip for parallel detection of biomarkers for diagnosis of a Systemic Inflammatory Response Syndrome (SIRS) in human serum
    Authors: A Stumpf, T Brandstett, J Hübner, J Rühe
    PLoS ONE, 2019;14(12):e0225525.
    Species: Human
    Sample Types: Serum
    Applications: ELISA Standard
  82. The role of endothelial MERTK during the inflammatory response in lungs
    Authors: Y Li, ES Wittchen, E Monaghan-B, C Hahn, HS Earp, CM Doerschuk, K Burridge
    PLoS ONE, 2019;14(12):e0225051.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Integrated microRNA/mRNA expression profiling of the skin of psoriasis patients
    Authors: D Deli?, K Wolk, R Schmid, O Gabrielyan, D Christou, K Rieber, M Rolser, I Jakob, F Wiech, M Griesser, C Wohnhaas, G Kokolakis, E Witte-Händ, P Baum, R Sabat
    J. Dermatol. Sci., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Iguratimod Inhibits the Aggressiveness of Rheumatoid Fibroblast-Like Synoviocytes
    Authors: J Lin, Y Yu, X Wang, Y Ke, C Sun, L Yue, G Xu, B Xu, L Xu, H Cao, D Xu, N Olsen, W Chen
    J Immunol Res, 2019;2019(0):6929286.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  85. S100A4/non-muscle myosin II signaling regulates epithelial-mesenchymal transition and stemness in uterine carcinosarcoma
    Authors: M Tochimoto, Y Oguri, M Hashimura, R Konno, T Matsumoto, A Yokoi, Y Kodera, M Saegusa
    Lab. Invest., 2019;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Fisetin, a 3,7,3',4'-Tetrahydroxyflavone Inhibits the PI3K/Akt/mTOR and MAPK Pathways and Ameliorates Psoriasis Pathology in 2D and 3D Organotypic Human Inflammatory Skin Models
    Authors: JC Chamcheu, S Esnault, VM Adhami, AL Noll, S Banang-Mbe, T Roy, SS Singh, S Huang, KG Kousoulas, H Mukhtar
    Cells, 2019;8(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Effector memory differentiation increases detection of replication-competent HIV-l in resting CD4+ T cells from virally suppressed individuals
    Authors: ER Wonderlich, K Subramania, B Cox, A Wiegand, C Lackman-Sm, MJ Bale, M Stone, R Hoh, MF Kearney, F Maldarelli, SG Deeks, MP Busch, RG Ptak, DA Kulpa
    PLoS Pathog., 2019;15(10):e1008074.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  88. TSG-6 in conditioned media from adipose mesenchymal stem cells protects against visual deficits in mild traumatic brain injury model through neurovascular modulation
    Authors: KA Jha, M Pentecost, R Lenin, J Gentry, L Klaic, N Del Mar, A Reiner, CH Yang, LM Pfeffer, N Sohl, R Gangaraju
    Stem Cell Res Ther, 2019;10(1):318.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  89. Intervention for early diabetic nephropathy by mesenchymal stem cells in a preclinical nonhuman primate model
    Authors: X An, G Liao, Y Chen, A Luo, J Liu, Y Yuan, L Li, L Yang, H Wang, F Liu, G Yang, S Yi, Y Li, J Cheng, Y Lu
    Stem Cell Res Ther, 2019;10(1):363.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  90. Intra-pancreatic tissue-derived mesenchymal stromal cells: a promising therapeutic potential with anti-inflammatory and pro-angiogenic profiles
    Authors: B Khiatah, M Qi, W Du, K T-Chen, KM van Megen, RG Perez, JS Isenberg, F Kandeel, BO Roep, HT Ku, IH Al-Abdulla
    Stem Cell Res Ther, 2019;10(1):322.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  91. Optimal Inhibition of Choroidal Neovascularization by scAAV2 with VMD2 Promoter-driven Active Rap1a in the RPE
    Authors: H Wang, E Kunz, GJ Stoddard, WW Hauswirth, ME Hartnett
    Sci Rep, 2019;9(1):15732.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  92. CD8+ T cell-mediated endotheliopathy is a targetable mechanism of neuro-inflammation in Susac syndrome
    Authors: CC Gross, C Meyer, U Bhatia, L Yshii, I Kleffner, J Bauer, AR Tröscher, A Schulte-Me, S Herich, T Schneider-, H Plate, T Kuhlmann, M Schwaninge, W Brück, M Pawlitzki, DA Laplaud, D Loussouarn, J Parratt, M Barnett, ME Buckland, TA Hardy, SW Reddel, M Ringelstei, J Dörr, B Wildemann, M Kraemer, H Lassmann, R Höftberger, E Beltrán, K Dornmair, N Schwab, L Klotz, SG Meuth, G Martin-Blo, H Wiendl, R Liblau
    Nat Commun, 2019;10(1):5779.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  93. Context-specific regulation of surface and soluble IL7R expression by an autoimmune risk allele
    Authors: H Al-Mossawi, N Yager, CA Taylor, E Lau, S Danielli, J de Wit, J Gilchrist, I Nassiri, EA Mahe, W Lee, L Rizvi, S Makino, J Cheeseman, M Neville, JC Knight, P Bowness, BP Fairfax
    Nat Commun, 2019;10(1):4575.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Anti-interleukin-6 receptor antibody treatment ameliorates postoperative adhesion formation
    Authors: N Uyama, H Tsutsui, S Wu, K Yasuda, E Hatano, XY Qin, S Kojima, J Fujimoto
    Sci Rep, 2019;9(1):17558.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC-P
  95. An Autocrine Wnt5a Loop Promotes NF-kappaB Pathway Activation and Cytokine/Chemokine Secretion in Melanoma
    Authors: G Barbero, MV Castro, MB Villanueva, MJ Quezada, NB Fernández, S DeMorrow, P Lopez-Berg
    Cells, 2019;8(9):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  96. Progranulin attenuates liver fibrosis by downregulating the inflammatory response
    Authors: W Yoo, J Lee, KH Noh, S Lee, D Jung, MH Kabir, D Park, C Lee, KS Kwon, JS Kim, S Kim
    Cell Death Dis, 2019;10(10):758.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  97. Tissue-regenerative potential of the secretome of gamma-irradiated peripheral blood mononuclear cells is mediated via TNFRSF1B-induced necroptosis
    Authors: E Simader, L Beer, M Laggner, V Vorstandle, A Gugerell, M Erb, P Kalinina, D Copic, D Moser, A Spittler, E Tschachler, H Jan Ankers, M Mildner
    Cell Death Dis, 2019;10(10):729.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Bioassay
  98. High-Mobility Group Box 1 in Dry Eye Inflammation
    Authors: C Lema, RY Reins, RL Redfern
    Invest. Ophthalmol. Vis. Sci., 2018;59(5):1741-1750.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Antigen presentation of the Oct4 and Sox2 peptides by CD154-activated B lymphocytes enhances the killing effect of cytotoxic T lymphocytes on tumor stem-like cells derived from cisplatin-resistant lung cancer cells
    Authors: X Zhang, Y Zhang, J Xu, H Wang, X Zheng, Y Lou, B Han
    J Cancer, 2018;9(2):367-374.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  100. IL-38 has an anti-inflammatory action in psoriasis and its expression correlates with disease severity and therapeutic response to anti-IL-17A treatment
    Authors: L Mercurio, M Morelli, C Scarponi, EZ Eisenmesse, N Doti, G Pagnanelli, E Gubinelli, C Mazzanti, A Cavani, M Ruvo, CA Dinarello, C Albanesi, S Madonna
    Cell Death Dis, 2018;9(11):1104.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  101. Long Non-Coding RNA Urothelial Carcinoma Associated 1 Promotes Proliferation, Migration and Invasion of Osteosarcoma Cells by Regulating microRNA-182
    Authors: Q Li, W Xing, X Gong, Y Wang
    Cell. Physiol. Biochem., 2018;51(3):1149-1163.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Restoration of E-cadherin by PPBICA protects against cisplatin-induced acute kidney injury by attenuating inflammation and programmed cell death
    Authors: L Gao, MM Liu, HM Zang, QY Ma, Q Yang, L Jiang, GL Ren, HD Li, WF Wu, JN Wang, B Wei, XQ Liu, C Jiang, C Huang, J Li, XM Meng
    Lab. Invest., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Astrocyte expression of the Drosophila TNF-alpha homologue, Eiger, regulates sleep in flies
    Authors: WM Vanderheyd, AG Goodman, RH Taylor, MG Frank, HPA Van Dongen, JR Gerstner
    PLoS Genet., 2018;14(10):e1007724.
    Species: Drosophila
    Sample Types: In Vivo
    Applications: In Vivo
  104. LncRNA Meg3 protects endothelial function by regulating the DNA damage response
    Authors: MS Shihabudee, X Cheng, M Moran, S Haemmig, MJ Naldrett, S Alvarez, MW Feinberg, X Sun
    Nucleic Acids Res., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Proton irradiation orchestrates macrophage reprogramming through NF?B signaling
    Authors: G Genard, AC Wera, C Huart, B Le Calve, S Penninckx, A Fattacciol, T Tabarrant, C Demazy, N Ninane, AC Heuskin, S Lucas, C Michiels
    Cell Death Dis, 2018;9(7):728.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Aberrant STAT phosphorylation signaling in peripheral blood mononuclear cells from multiple sclerosis patients
    Authors: E Canto, N Isobe, A Didonna,, SL Hauser, JR Oksenberg
    J Neuroinflammation, 2018;15(1):72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  107. C/EBP? drives interactions between human MAIT cells and endothelial cells that are important for extravasation
    Authors: CH Lee, HH Zhang, SP Singh, L Koo, J Kabat, H Tsang, TP Singh, JM Farber
    Elife, 2018;7(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  108. Bridging pro-inflammatory signals, synaptic transmission and protection in spinal explants in vitro
    Authors: M Medelin, V Giacco, A Aldinucci, G Castronovo, E Bonechi, A Sibilla, M Tanturli, M Torcia, L Ballerini, F Cozzolino, C Ballerini
    Mol Brain, 2018;11(1):3.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  109. EpCAM peptide-primed dendritic cell vaccination confers significant anti-tumor immunity in hepatocellular carcinoma cells
    Authors: YJ Choi, SJ Park, YS Park, HS Park, KM Yang, K Heo
    PLoS ONE, 2018;13(1):e0190638.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Nucleoside Diphosphate Kinase-3 (NME3) Enhances TLR5-Induced NF-?B Activation
    Authors: K Flentie, C Gonzalez, B Kocher, Y Wang, H Zhu, J Marasa, D Piwnica-Wo
    Mol. Cancer Res., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Hyaluronic Acid Influence on Normal and Osteoarthritic Tissue-Engineered Cartilage
    Authors: S Hemmati-Sa, J Ringe, T Dehne, R Haag, M Sittinger
    Int J Mol Sci, 2018;19(5):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  112. A20 regulates canonical wnt-signaling through an interaction with RIPK4
    Authors: BN Nakamura, A Glazier, MG Kattah, B Duong, Y Jia, D Campo, L Shao
    PLoS ONE, 2018;13(5):e0195893.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Galectin-3 Plays an Important Role in Preterm Birth Caused by Dental Infection of Porphyromonas gingivalis
    Authors: M Miyauchi, M Ao, H Furusho, C Chea, A Nagasaki, S Sakamoto, T Ando, T Inubushi, K Kozai, T Takata
    Sci Rep, 2018;8(1):2867.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  114. The p55TNFR-IKK2-Ripk3 axis orchestrates arthritis by regulating death and inflammatory pathways in synovial fibroblasts
    Authors: M Armaka, C Ospelt, M Pasparakis, G Kollias
    Nat Commun, 2018;9(1):618.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  115. LRRC15 promotes osteogenic differentiation of mesenchymal stem cells by modulating p65 cytoplasmic/nuclear translocation
    Authors: Y Wang, Y Liu, M Zhang, L Lv, X Zhang, P Zhang, Y Zhou
    Stem Cell Res Ther, 2018;9(1):65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Neutrophils induce macrophage anti-inflammatory reprogramming by suppressing NF-?B activation
    Authors: JA Marwick, R Mills, O Kay, K Michail, J Stephen, AG Rossi, I Dransfield, N Hirani
    Cell Death Dis, 2018;9(6):665.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  117. Activation of Activin receptor-like kinases curbs mucosal inflammation and proliferation in chronic rhinosinusitis with nasal polyps
    Authors: L Tengroth, J Arebro, O Larsson, C Bachert, SK Georén, LO Cardell
    Sci Rep, 2018;8(1):1561.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  118. ANKRD1 regulates innate immune responses against herpes simplex virus 1: A potential role in eczema herpeticum
    Authors: L Bin, X Li, B Richers, JE Streib, JW Hu, P Taylor, DYM Leung
    J. Allergy Clin. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  119. Mitocryptides from Human Mitochondrial DNA-Encoded Proteins Activate Neutrophil Formyl Peptide Receptors: Receptor Preference and Signaling Properties
    Authors: M Gabl, M Sundqvist, A Holdfeldt, S Lind, J Mårtensson, K Christenso, T Marutani, C Dahlgren, H Mukai, H Forsman
    J. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  120. Interactome analysis of transforming growth factor-?-activated kinase 1 inHelicobacter pylori-infected cells revealed novel regulators tripartite motif 28 and CDC37
    Authors: O Sokolova, T Kähne, K Bryan, M Naumann
    Oncotarget, 2018;9(18):14366-14381.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Nuclear Translocation of Argonaute 2 in Cytokine-Induced Senescence
    Authors: M Rentschler, Y Chen, J Pahl, L Soria-Mart, H Braumüller, E Brenner, O Bischof, M Röcken, T Wieder
    Cell. Physiol. Biochem., 2018;51(3):1103-1118.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  122. Arsenite exposure potentiates apoptosis-inducing effects of tumor necrosis factor-alpha- through reactive oxygen species
    Authors: P Singhirunn, B Moolmuang, K Lirdprapam, M Ruchirawat
    J Toxicol Sci, 2018;43(2):159-169.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Sulforaphane rescues amyloid-? peptide-mediated decrease in MerTK expression through its anti-inflammatory effect in human THP-1 macrophages
    Authors: KA Jhang, JS Park, HS Kim, YH Chong
    J Neuroinflammation, 2018;15(1):75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  124. ICAM1 expression is induced by proinflammatory cytokines and associated with TLS formation in aggressive breast cancer subtypes
    Authors: SL Figenschau, E Knutsen, I Urbarova, C Fenton, B Elston, M Perander, ES Mortensen, KA Fenton
    Sci Rep, 2018;8(1):11720.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  125. Association of NF-E2 Related Factor 2 (Nrf2) and inflammatory cytokines in recent onset Type 2 Diabetes Mellitus
    Authors: D Sireesh, U Dhamodhara, K Ezhilarasi, V Vijay, KM Ramkumar
    Sci Rep, 2018;8(1):5126.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  126. Characterization of the enhancer and promoter landscape of inflammatory bowel disease from human colon biopsies
    Authors: M Boyd, M Thodberg, M Vitezic, J Bornholdt, K Vitting-Se, Y Chen, M Coskun, Y Li, BZS Lo, P Klausen, P Jan Schwei, AG Pedersen, N Rapin, K Skovgaard, K Dahlgaard, R Andersson, TB Terkelsen, B Lilje, JT Troelsen, AM Petersen, KB Jensen, I Gögenur, P Thielsen, JB Seidelin, OH Nielsen, JT Bjerrum, A Sandelin
    Nat Commun, 2018;9(1):1661.
    Species: Human
    Sample Types: Organoids
    Applications: Bioassay
  127. DDIT4 and Associated lncDDIT4 Modulate Th17 Differentiation through the DDIT4/TSC/mTOR Pathway
    Authors: F Zhang, G Liu, D Li, C Wei, J Hao
    J. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  128. The proximal tubular ?7 nicotinic acetylcholine receptor attenuates ischemic acute kidney injury through Akt/PKC signaling-mediated HO-1 induction
    Authors: H Kim, SR Kim, J Je, K Jeong, S Kim, HJ Kim, KC Chang, SW Park
    Exp. Mol. Med., 2018;50(4):40.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Sodium Butyrate Attenuates Diarrhea in Weaned Piglets and Promotes Tight Junction Protein Expression in Colon in a GPR109A-Dependent Manner
    Authors: W Feng, Y Wu, G Chen, S Fu, B Li, B Huang, D Wang, W Wang, J Liu
    Cell. Physiol. Biochem., 2018;47(4):1617-1629.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  130. Effects of bone marrow-derived mesenchymal stromal cells on gene expression in human alveolar type II cells exposed to TNF-?, IL-1?, and IFN-?
    Authors: M Schwede, EM Wilfong, RL Zemans, PJ Lee, C Dos Santos, X Fang, MA Matthay
    Physiol Rep, 2018;6(16):e13831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Epithelial Smad4 Deletion Up-Regulates Inflammation and Promotes Inflammation-Associated Cancer
    Authors: AL Means, TJ Freeman, J Zhu, LG Woodbury, P Marincola-, C Wu, AR Meyer, CJ Weaver, C Padmanabha, H An, J Zi, BC Wessinger, R Chaturvedi, TD Brown, NG Deane, RJ Coffey, KT Wilson, JJ Smith, CL Sawyers, JR Goldenring, SV Novitskiy, MK Washington, C Shi, RD Beauchamp
    Cell Mol Gastroenterol Hepatol, 2018;6(3):257-276.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. TRAIL and Ceruloplasmin Inverse Correlation as a Representative Crosstalk between Inflammation and Oxidative Stress
    Authors: V Tisato, S Gallo, E Melloni, C Celeghini, A Passaro, G Zauli, P Secchiero, C Bergamini, A Trentini, G Bonaccorsi, G Valacchi, G Zuliani, C Cervellati
    Mediators Inflamm., 2018;2018(0):9629537.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Elevated Expression of AXL May Contribute to the Epithelial-to-Mesenchymal Transition in Inflammatory Bowel Disease Patients
    Authors: É Boros, Z Kellermaye, P Balogh, G Strifler, A Vörös, P Sarlós, Á Vincze, C Varga, I Nagy
    Mediators Inflamm., 2018;2018(0):3241406.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  134. ADAM-17 is expressed on rheumatoid arthritis fibroblast-like synoviocytes and regulates proinflammatory mediator expression and monocyte adhesion
    Authors: S Ishii, T Isozaki, H Furuya, H Takeuchi, Y Tsubokura, K Inagaki, T Kasama
    Arthritis Res. Ther., 2018;20(1):159.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  135. Induction of innate immune memory via microRNA targeting of chromatin remodelling factors
    Authors: JJ Seeley, RG Baker, G Mohamed, T Bruns, MS Hayden, SD Deshmukh, DE Freedberg, S Ghosh
    Nature, 2018;559(7712):114-119.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Protective mechanisms of resveratrol derivatives against TNF-?-induced inflammatory responses in rat mesangial cells
    Authors: IT Lee, CF Lin, YL Huang, KY Chong, MF Hsieh, TH Huang, CY Cheng
    Cytokine, 2018;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  137. XAF1 forms a positive feedback loop with IRF-1 to drive apoptotic stress response and suppress tumorigenesis
    Authors: SI Jeong, JW Kim, KP Ko, BK Ryu, MG Lee, HJ Kim, SG Chi
    Cell Death Dis, 2018;9(8):806.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  138. Catalase Enhances Viability of Human Chondrocytes in Culture by Reducing Reactive Oxygen Species and Counteracting Tumor Necrosis Factor-?-Induced Apoptosis
    Authors: S Li, X Yang, Z Feng, P Wang, W Zhu, S Cui
    Cell. Physiol. Biochem., 2018;49(6):2427-2442.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  139. Activation of calcium-sensing receptor by allosteric agonists cinacalcet and AC-265347 abolishes the 1,25(OH)2D3-induced Ca2+ transport: Evidence that explains how the intestine prevents excessive Ca2+ absorption
    Authors: K Wongdee, M Rodrat, C Keadsai, W Jantarajit, J Teerapornp, J Thongbunch, N Charoenpha
    Arch. Biochem. Biophys., 2018;657(0):15-22.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Anacardic acid suppresses fibroblast-like synoviocyte proliferation and invasion and ameliorates collagen-induced arthritis in a mouse model
    Authors: GH Yang, C Zhang, N Wang, Y Meng, YS Wang
    Cytokine, 2018;111(0):350-356.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  141. Virus-like infection induces human ? cell dedifferentiation
    Authors: M Oshima, KP Knoch, M Diedisheim, A Petzold, P Cattan, M Bugliani, P Marchetti, P Choudhary, GC Huang, SR Bornstein, M Solimena, O Albagli-Cu, R Scharfmann
    JCI Insight, 2018;3(3):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Human iPS-Derived Astroglia from a Stable Neural Precursor State Show Improved Functionality Compared with Conventional Astrocytic Models
    Authors: A Lundin, L Delsing, M Clausen, P Ricchiuto, J Sanchez, A Sabirsh, M Ding, J Synnergren, H Zetterberg, G Brolén, R Hicks, A Herland, A Falk
    Stem Cell Reports, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  143. Presenilin 1 Regulates NF-?B Activation via Association with Breakpoint Cluster Region and Casein Kinase II
    Authors: Y Tanaka, L Sabharwal, M Ota, I Nakagawa, JJ Jiang, Y Arima, H Ogura, M Okochi, M Ishii, D Kamimura, M Murakami
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  144. Tumor necrosis factor-like weak inducer of apoptosis induces inflammation in Graves' orbital fibroblasts
    Authors: SJ Lee, J Kim, J Ko, EJ Lee, HJ Koh, JS Yoon
    PLoS ONE, 2018;13(12):e0209583.
    Species: Human
    Sample Types: Whole Cells
  145. Human Induced Pluripotent Stem Cell-Derived Astrocytes Are Differentially Activated by Multiple Sclerosis-Associated Cytokines
    Authors: S Perriot, A Mathias, G Perriard, M Canales, N Jonkmans, N Merienne, C Meunier, L El Kassar, AL Perrier, DA Laplaud, M Schluep, N Déglon, R Du Pasquie
    Stem Cell Reports, 2018;11(5):1199-1210.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Cell Size-Based Decision-Making of a Viral Gene Circuit
    Authors: K Bohn-Wippe, EN Tevonian, Y Lu, MY Huang, MR Megaridis, RD Dar
    Cell Rep, 2018;25(13):3844-3857.e5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Agrimonia procera exerts antimicrobial effects, modulates the expression of defensins and cytokines in colonocytes and increases the immune response in lipopolysaccharide-challenged piglets
    Authors: T Gräber, H Kluge, S Granica, G Horn, J Kalbitz, C Brandsch, A Breitenste, C Brütting, GI Stangl
    BMC Vet. Res., 2018;14(1):346.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Divergent TCR-Initiated Calcium Signals Govern Recruitment versus Activation of Human Alloreactive Effector Memory T Cells by Endothelial Cells
    Authors: TD Manes, V Wang, JS Pober
    J. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  149. CellCycleTRACER accounts for cell cycle and volume in mass cytometry data
    Authors: MA Rapsomanik, XK Lun, S Woerner, M Laumanns, B Bodenmille, MR Martínez
    Nat Commun, 2018;9(1):632.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  150. The induced RNA-binding protein, HuR targets 3'-UTR region of IL-6 mRNA and enhances its stabilization in periodontitis
    Authors: K Ouhara, S Munenaga, M Kajiya, K Takeda, S Matsuda, Y Sato, Y Hamamoto, T Iwata, S Yamasaki, K Akutagawa, N Mizuno, T Fujita, E Sugiyama, H Kurihara
    Clin. Exp. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  151. RNA sensor LGP2 inhibits TRAF ubiquitin ligase to negatively regulate innate immune signaling
    Authors: JP Parisien, JJ Lenoir, R Mandhana, KR Rodriguez, K Qian, AM Bruns, CM Horvath
    EMBO Rep., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Strigolactone GR24 and pinosylvin attenuate adipogenesis and inflammation of white adipocytes
    Authors: S Modi, N Yaluri, T Kokkola
    Biochem. Biophys. Res. Commun., 2018;0(0):.
    Species: Mouse
    Sample Types: 3T3-L1 adipocytes
    Applications: Bioassay
  153. NF-?B inducing kinase is a therapeutic target for systemic lupus erythematosus
    Authors: HD Brightbill, E Suto, N Blaquiere, N Ramamoorth, S Sujatha-Bh, EB Gogol, GM Castanedo, BT Jackson, YC Kwon, S Haller, J Lesch, K Bents, C Everett, PB Kohli, S Linge, L Christian, K Barrett, A Jaochico, LM Berezhkovs, PW Fan, Z Modrusan, K Veliz, MJ Townsend, J DeVoss, AR Johnson, R Godemann, WP Lee, CD Austin, BS McKenzie, JA Hackney, JJ Crawford, ST Staben, MH Alaoui Ism, LC Wu, N Ghilardi
    Nat Commun, 2018;9(1):179.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Anisakis pegreffii impacts differentiation and function of human dendritic cells
    Authors: C Napoletano, S Mattiucci, A Colantoni, F Battisti, IG Zizzari, H Rahimi, M Nuti, A Rughetti
    Parasite Immunol., 2018;0(0):e12527.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Unraveling the interplay between senescent dermal fibroblasts and cutaneous squamous cell carcinoma cell lines at different stages of tumorigenesis
    Authors: M Toutfaire, E Dumortier, A Fattacciol, MV Steenbrugg, CM Proby, F Debacq-Cha
    Int. J. Biochem. Cell Biol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  156. EBI2 regulates pro-inflammatory signalling and cytokine release in astrocytes
    Authors: A Rutkowska, DR Shimshek, AW Sailer, KK Dev
    Neuropharmacology, 2018;133(0):121-128.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Seizure progression and inflammatory mediators promote pericytosis and pericyte-microglia clustering at the cerebrovasculature
    Authors: W Klement, R Garbelli, E Zub, L Rossini, L Tassi, B Girard, M Blaquiere, F Bertaso, J Perroy, F de Bock, N Marchi
    Neurobiol. Dis., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  158. Beta cell extracellular vesicle miR-21-5p cargo is increased in response to inflammatory cytokines and serves as a biomarker of type 1 diabetes
    Authors: AJ Lakhter, RE Pratt, RE Moore, KK Doucette, BF Maier, LA DiMeglio, EK Sims
    Diabetologia, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  159. Dynamic imaging of adaptive stress response pathway activation for prediction of drug induced liver injury
    Authors: S Wink, SW Hiemstra, S Huppelscho, JE Klip, B van de Wat
    Arch. Toxicol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Synergistic effect of interleukin-17 and tumor necrosis factor-α on inflammatory response in hepatocytes through interleukin-6 dependent and independent pathways
    Authors: A Beringer, N Thiam, J Molle, B Bartosch, P Miossec
    Clin. Exp. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Voriconazole-induced photocarcinogenesis is promoted by aryl hydrocarbon receptor-dependent COX-2 upregulation
    Authors: S Ikeya, JI Sakabe, T Yamada, T Naito, Y Tokura
    Sci Rep, 2018;8(1):5050.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  162. TLR3 Ligand Poly(I:C) Exerts Distinct Actions in Synovial Fibroblasts When Delivered by Extracellular Vesicles
    Authors: M Frank-Bert, DS Pisetsky, C Kolling, BA Michel, RE Gay, A Jüngel, S Gay
    Front Immunol, 2018;9(0):28.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Matrix metalloproteinase-9 (MMP9) is involved in the TNF-α-induced fusion of human M13SV1-Cre breast epithelial cells and human MDA-MB-435-pFDR1 cancer cells
    Authors: J Weiler, M Mohr, KS Zänker, T Dittmar
    Cell Commun. Signal, 2018;16(1):14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  164. BTKCys481Serdrives ibrutinib resistance via ERK1/2, and protects BTKWild-TypeMYD88 mutated cells by a paracrine mechanism
    Authors: JG Chen, X Liu, M Munshi, L Xu, N Tsakmaklis, MG Demos, A Kofides, ML Guerrera, GG Chan, CJ Patterson, KE Meid, J Gustine, T Dubeau, P Severns, JJ Castillo, ZR Hunter, J Wang, SJ Buhrlage, NS Gray, SP Treon, G Yang
    Blood, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Up-regulation of SFTPB expression and attenuation of acute lung injury by pulmonary epithelial cell-specific NAMPT knockdown
    Authors: G Bi, L Wu, P Huang, S Islam, DP Heruth, LQ Zhang, DY Li, V Sampath, W Huang, BA Simon, RB Easley, SQ Ye
    FASEB J., 2018;0(0):fj201701059R.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Progesterone Inhibits Apoptosis in Fetal Membranes by Altering Expression of Both Pro- and Antiapoptotic Proteins
    Authors: Y Wang, VM Abrahams, G Luo, NG Norwitz, VV Snegovskik, SW Ng, ER Norwitz
    Reprod Sci, 2018;0(0):1933719118759.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  167. Changes in the Anti-Allergic Activities of Sesame by Bioconversion
    Authors: TD Jung, SI Choi, SH Choi, BY Cho, WS Sim,, SJ Lee, SJ Park, DB Kim, YC Kim, JH Lee, OH Lee
    Nutrients, 2018;10(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Regulation of fibroblast Fas expression by soluble and mechanical pro-fibrotic stimuli
    Authors: AE Dodi, IO Ajayi, C Chang, M Beard, SL Ashley, SK Huang, VJ Thannickal, DJ Tschumperl, TH Sisson, JC Horowitz
    Respir. Res., 2018;19(1):91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  169. Filifactor alocis modulates human neutrophil antimicrobial functional responses
    Authors: JS Edmisson, S Tian, CL Armstrong, A Vashishta, CK Klaes, I Miralda, E Jimenez-Fl, J Le, Q Wang, RJ Lamont, SM Uriarte
    Cell. Microbiol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  170. An anti-TL1A antibody for the treatment of asthma and inflammatory bowel disease
    Authors: AW Clarke, L Poulton, D Shim, D Mabon, D Butt, M Pollard, V Pande, J Husten, J Lyons, C Tian, AG Doyle
    MAbs, 2018;0(0):1-43.
    Species: Human
    Sample Types: Recombinant Protein
    Applications: Surface Plasmon Resonance (SPR
  171. RNA-Seq Analysis of IL-1B and IL-36 Responses in Epidermal Keratinocytes Identifies a Shared MyD88-Dependent Gene Signature
    Authors: WR Swindell, MA Beamer, MK Sarkar, S Loftus, J Fullmer, X Xing, NL Ward, LC Tsoi, MJ Kahlenberg, Y Liang, JE Gudjonsson
    Front Immunol, 2018;9(0):80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  172. mTORC1/2 inhibitor and curcumin induce apoptosis through lysosomal membrane permeabilization-mediated autophagy
    Authors: SU Seo, SM Woo, HS Lee, SH Kim, KJ Min, TK Kwon
    Oncogene, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Streamlined circular proximity ligation assay provides high stringency and compatibility with low-affinity antibodies
    Authors: R Jalili, J Horecka, JR Swartz, RW Davis, HHJ Persson
    Proc. Natl. Acad. Sci. U.S.A., 2018;0(0):.
    Applications: Bioassay
  174. Lipoxin A4 Attenuates the Inflammatory Response in Stem Cells of the Apical Papilla via ALX/FPR2
    Authors: A Gaudin, M Tolar, OA Peters
    Sci Rep, 2018;8(1):8921.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  175. Role of thyroid transcription factor-1 in transcriptional regulation of heme oxygenase-1
    Authors: B Jeong, HR Kim, NS Choi, BS Park, H Eom, JW Park, JG Kim, BJ Lee
    Biochem. Biophys. Res. Commun., 2018;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  176. Enhanced Utilization of Induced Pluripotent Stem Cell-Derived Human Intestinal Organoids Using Microengineered Chips.
    Authors: Michael J Workman, John P Gleeson, Elissa J Troisi, Hannah Q Estrada, S Jordan Kerns, Christopher D Hinojosa, Geraldine A Hamilton, Stephan R Targan, Clive N Svendsen, Robert J Barrett
    Cellular and Molecular Gastroenterology and Hepatology, 2018;0(0):2352-345X.
    Species: Human
    Sample Types: Whole Cells on Intestine Chip
    Applications: Bioassay
  177. The IL20 Genetic Polymorphism Is Associated with Altered Clinical Outcome in Septic Shock
    Authors: TA Nakada, P Wacharasin, JA Russell, JH Boyd, E Nakada, SA Thair, T Shimada, KR Walley
    J Innate Immun, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Leukadherin-1 ameliorates endothelial barrier damage mediated by neutrophils from critically ill patients
    Authors: CM Dickinson, BW LeBlanc, MM Edhi, DS Heffernan, MH Faridi, V Gupta, WG Cioffi, X O'Brien, JS Reichner
    J Intensive Care, 2018;6(0):19.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
    Authors: R Drolia, S Tenguria, AC Durkes, JR Turner, AK Bhunia
    Cell Host Microbe, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  180. RvD1 inhibits TNF?-induced c-Myc expression in normal intestinal epithelial cells and destabilizes hyper-expressed c-Myc in colon cancer cells
    Authors: X Zhong, HN Lee, YJ Surh
    Biochem. Biophys. Res. Commun., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  181. LAIR-1 shedding from human fibroblast-like synoviocytes in rheumatoid arthritis following TNF-? stimulation
    Authors: Y Zhang, S Wang, H Dong, X Yi, J Zhang, X Liu, R Zhuang, Y Ding
    Clin. Exp. Immunol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Effects of osteoprotegerin/TNFRSF11B in two models of abdominal aortic aneurysms
    Authors: E Vorkapic, A Kunath, D Wågsäter
    Mol Med Rep, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Bacteroides fragilis Toxin Coordinates a Pro-carcinogenic Inflammatory Cascade via Targeting of Colonic Epithelial Cells
    Authors: L Chung, ET Orberg, AL Geis, JL Chan, K Fu, CED Shields, CM Dejea, P Fathi, J Chen, BB Finard, AJ Tam, FM McAllister, H Fan, X Wu, S Ganguly, A Lebid, P Metz, SW Van Meerbe, DL Huso, EC Wick, DM Pardoll, F Wan, S Wu, CL Sears, F Housseau
    Cell Host Microbe, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Lymphatic exosomes promote dendritic cell migration along guidance cues
    Authors: M Brown, LA Johnson, DA Leone, P Majek, K Vaahtomeri, D Senfter, N Bukosza, H Schachner, G Asfour, B Langer, R Hauschild, K Parapatics, YK Hong, KL Bennett, R Kain, M Detmar, M Sixt, DG Jackson, D Kerjaschki
    J. Cell Biol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Class 1-selective histone deacetylase inhibitors enhance HIV latency reversal while preserving the activity of HDAC isoforms necessary for maximal HIV gene expression
    Authors: TD Zaikos, MM Painter, NT Sebastian, VH Terry, KL Collins
    J. Virol., 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Angiokine Wisp-1 is increased in myocardial infarction and regulates cardiac endothelial signaling
    Authors: LH Wright, DJ Herr, SS Brown, H Kasiganesa, DR Menick
    JCI Insight, 2018;3(4):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Interleukin-20 is triggered by TLR ligands and associates with disease activity in patients with rheumatoid arthritis
    Authors: L Šenolt, K Prajzlerov, H Hulejová, B Šumová, M Filková, D Veigl, K Pavelka, J Vencovský
    Cytokine, 2017;97(0):187-192.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Comprehensive proteome analysis of human skeletal muscle in cachexia and sarcopenia: A pilot study
    Authors: HA Ebhardt, S Degen, V Tadini, A Schilb, N Johns, CA Greig, KC Fearon, R Aebersold, C Jacobi
    J Cachexia Sarcopenia Muscle, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  189. In�vitro model of cerebral ischemia by using brain microvascular endothelial cells derived from human induced pluripotent stem cells
    Authors: Y Kokubu, T Yamaguchi, K Kawabata
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Doxofylline does not increase formoterol-induced cAMP nor MKP-1 expression in ASM cells resulting in lack of anti-inflammatory effect
    Authors: BS Patel, MJ Kugel, G Baehring, AJ Ammit
    Pulm Pharmacol Ther, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  191. Lysosomal destabilization activates the NLRP3 inflammasome in human umbilical vein endothelial cells (HUVECs)
    Authors: K Kinnunen, N Piippo, S Loukovaara, M Hytti, K Kaarnirant, A Kauppinen
    J Cell Commun Signal, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  192. iTRAQ quantitative proteomic study in patients with thoracic ossification of the ligamentum flavum
    Authors: B Wang, Z Chen, X Meng, M Li, X Yang, C Zhang
    Biochem. Biophys. Res. Commun., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Substance P enhances proliferation and paracrine potential of adipose-derived stem cells in�vitro
    Authors: S Kim, J Piao, Y Son, HS Hong
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques
    Authors: SR DiNapoli, AM Ortiz, F Wu, K Matsuda, HL Twigg, VM Hirsch, K Knox, JM Brenchley
    JCI Insight, 2017;2(4):e91214.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Types: Whole Cells
    Applications: Bioassay
  195. Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis
    Authors: E Couderc, F Morel, P Levillain, A Buffière-M, M Camus, C Paquier, C Bodet, JF Jégou, M Pohin, L Favot, M Garcia, V Huguier, J Mcheik, C Lacombe, H Yssel, G Guillet, FX Bernard, JC Lecron
    PLoS ONE, 2017;12(7):e0181486.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  196. MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866
    Authors: P Huang, MW Lee, K Sadrerafi, DP Heruth, LQ Zhang, D Maulik, SQ Ye
    Drug Des Devel Ther, 2017;11(0):629-641.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Unique molecular profile of exosomes derived from primary human proximal tubular epithelial cells under diseased conditions
    Authors: X Wang, R Wilkinson, K Kildey, J Potriquet, J Mulvenna, RJ Lobb, A Möller, N Cloonan, P Mukhopadhy, AJ Kassianos, H Healy
    J Extracell Vesicles, 2017;6(1):1314073.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  198. A double-negative feedback loop between EpCAM and ERK contributes to the regulation of epithelial-mesenchymal transition in cancer
    Authors: NV Sankpal, TP Fleming, PK Sharma, HJ Wiedner, WE Gillanders
    Oncogene, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells
    Authors: NT Hogan, MB Whalen, LK Stolze, NK Hadeli, MT Lam, JR Springstea, CK Glass, CE Romanoski
    Elife, 2017;6(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Decitabine treatment sensitizes tumor cells to T-cell-mediated cytotoxicity in patients with myelodysplastic syndromes
    Authors: Z Zhang, Q He, Y Tao, J Guo, F Xu, LY Wu, YS Zhao, D Wu, LY Zhou, JY Su, LX Song, C Xiao, X Li, CK Chang
    Am J Transl Res, 2017;9(2):454-465.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  201. An Innovative High-Throughput Screening Approach for Discovery of Small Molecules That Inhibit TNF Receptors
    Authors: CH Lo, N Vunnam, AK Lewis, TL Chiu, BE Brummel, TM Schaaf, BD Grant, P Bawaskar, DD Thomas, JN Sachs
    SLAS Discov, 2017;0(0):2472555217706.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  202. IFN type I and II induce BAFF secretion from human decidual stromal cells
    Authors: AC Lundell, I Nordstr”m, K Andersson, C Lundqvist, E Telemo, S Nava, H Kaipe, A Rudin
    Sci Rep, 2017;7(0):39904.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  203. Tumor necrosis factor ? decreases aquaporin 3 expression in intestinal epithelial cells through inhibition of constitutive transcription
    Authors: MA Peplowski, AJ Vegso, V Iablokov, M Dicay, RS Zaheer, B Renaux, D Proud, MD Hollenberg, PL Beck, WK MacNaughto
    Physiol Rep, 2017;5(19):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  204. A Synthetic Mammalian Therapeutic Gene Circuit for Sensing and Suppressing Inflammation
    Authors: A Smole, D Lain??ek, U Bezeljak, S Horvat, R Jerala
    Mol. Ther, 2017;25(1):102-119.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  205. The anti-inflammatory function of HDL is impaired in type 2 diabetes: role of hyperglycemia, paraoxonase-1 and low grade inflammation
    Authors: S Ebtehaj, EG Gruppen, M Parvizi, UJF Tietge, RPF Dullaart
    Cardiovasc Diabetol, 2017;16(1):132.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  206. The involvement and possible mechanism of pro-inflammatory tumor necrosis factor alpha (TNF-?) in thoracic ossification of the ligamentum flavum
    Authors: C Zhang, Z Chen, X Meng, M Li, L Zhang, A Huang
    PLoS ONE, 2017;12(6):e0178986.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  207. Interferon-? induced insufficient autophagy contributes to p62-dependent apoptosis of epithelial cells in chronic rhinosinusitis with nasal polyps
    Authors: BF Wang, PP Cao, ZC Wang, ZY Li, ZZ Wang, J Ma, B Liao, YK Deng, XB Long, K Xu, H Wang, H Wang, M Zeng, X Lu, Z Liu
    Allergy, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Human Adaptive Immunity Rescues an Inborn Error of Innate Immunity
    Authors: L Israel, Y Wang, K Bulek, E Della Mina, Z Zhang, V Pedergnana, M Chrabieh, NA Lemmens, V Sancho-Shi, M Descatoire, T Lasseau, E Israelsson, L Lorenzo, L Yun, A Belkadi, A Moran, LE Weisman, F Vandenesch, F Batteux, S Weller, M Levin, J Herberg, A Abhyankar, C Prando, Y Itan, WJB van Wamel, C Picard, L Abel, D Chaussabel, X Li, B Beutler, PD Arkwright, JL Casanova, A Puel
    Cell, 2017;168(5):789-800.e10.
    Species: Human
    Sample Types: Whole Blood
    Applications: Activiation
  209. Upregulation of circulating microRNA-134 in adult-onset Still's disease and its use as potential biomarker
    Authors: TL Liao, YM Chen, CW Hsieh, HH Chen, HC Lee, WT Hung, KT Tang, DY Chen
    Sci Rep, 2017;7(1):4214.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  210. Association of HMGB1 with oxidative stress markers and regulators in PDR
    Authors: AM Abu El-Asr, K Alam, M Garcia-Ram, A Ahmad, MM Siddiquei, G Mohammad, A Mousa, G De Hertogh, G Opdenakker, R Simó
    Mol. Vis., 2017;23(0):853-871.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  211. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells
    Authors: R Santos, KC Vadodaria, BN Jaeger, A Mei, S Lefcochilo, APD Mendes, G Erikson, M Shokhirev, L Randolph-M, C Fredlender, S Dave, R Oefner, C Fitzpatric, M Pena, JJ Barron, M Ku, AM Denli, BE Kerman, P Charnay, JR Kelsoe, MC Marchetto, FH Gage
    Stem Cell Reports, 2017;8(6):1757-1769.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  212. Mollugin Has an Anti-Cancer Therapeutic Effect by Inhibiting TNF-?-Induced NF-?B Activation
    Authors: Z Wang, MY Li, C Mi, KS Wang, J Ma, X Jin
    Int J Mol Sci, 2017;18(8):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  213. ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
    Authors: JS Reyat, M Chimen, PJ Noy, J Szyroka, GE Rainger, MG Tomlinson
    J. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Autophagy Impairment by Helicobacter pylori-induced Methylation Silencing of MAP1LC3Av1 Promotes Gastric Carcinogenesis
    Authors: JS Muhammad, S Nanjo, T Ando, S Yamashita, T Maekita, T Ushijima, Y Tabuchi, T Sugiyama
    Int. J. Cancer, 2017;0(0):.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  215. MicroRNA-143 and -145 modulate the phenotype of synovial fibroblasts in rheumatoid arthritis
    Authors: BK Hong, S You, SA Yoo, D Park, D Hwang, CS Cho, WU Kim
    Exp. Mol. Med., 2017;49(8):e363.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  216. A possible role for neutrophils in allergic rhinitis revealed after cellular subclassification
    Authors: J Arebro, S Ekstedt, E Hjalmarsso, O Winqvist, S Kumlien Ge, LO Cardell
    Sci Rep, 2017;7(0):43568.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  217. STAT3/NF-?B-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer
    Authors: WY Kuo, L Hwu, CY Wu, JS Lee, CW Chang, RS Liu
    Theranostics, 2017;7(3):647-663.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  218. Suberanilohydroxamic Acid as a Pharmacological Kruppel-Like Factor 2 Activator That Represses Vascular Inflammation and Atherosclerosis
    Authors: Y Xu, S Xu, P Liu, M Koroleva, S Zhang, S Si, ZG Jin
    J Am Heart Assoc, 2017;6(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Proinflammatory Cytokines IL-6 and TNF-? Increased Telomerase Activity through NF-?B/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells
    Authors: SS Chung, Y Wu, Q Okobi, D Adekoya, M Atefi, O Clarke, P Dutta, JV Vadgama
    Mediators Inflamm., 2017;2017(0):5958429.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  220. The autocrine role of proteoglycan-4 (PRG4) in modulating osteoarthritic synoviocyte proliferation and expression of matrix degrading enzymes
    Authors: A Alquraini, M Jamal, L Zhang, T Schmidt, GD Jay, KA Elsaid
    Arthritis Res. Ther., 2017;19(1):89.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis
    Authors: H Al Faruque, JH Kang, SR Hwang, S Sung, MM Alam, KH Sa, EJ Nam, YR Byun, YM Kang
    PLoS ONE, 2017;12(4):e0176110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  222. Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation
    Authors: KA Bailey, FG Haj, SI Simon, AG Passerini
    Sci Rep, 2017;7(1):8196.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  223. AAV-based dual-reporter circuit for monitoring cell signaling in living human cells
    Authors: Z Zhang, Z Stickney, N Duong, K Curley, B Lu
    J Biol Eng, 2017;11(0):18.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  224. Suppression of human arthritis synovial fibroblasts inflammation using dexamethasone-carbon nanotubes via increasing caveolin-dependent endocytosis and recovering mitochondrial membrane potential
    Authors: YK Lee, SW Kim, JY Park, WC Kang, YJ Kang, D Khang
    Int J Nanomedicine, 2017;12(0):5761-5779.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  225. TNF?-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels
    Authors: AE van der Wi, IMC Vogels, CJF van Noorde, I Klaassen, RO Schlingema
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3496-3505.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  226. Healing of Preterm Ruptured Fetal Membranes
    Authors: H Mogami, A Hari Kisho, Y Akgul, RA Word
    Sci Rep, 2017;7(1):13139.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity
    Authors: D Sagar, NP Singh, R Ginwala, X Huang, R Philip, M Nagarkatti, P Nagarkatti, K Neumann, J Ruland, AM Andrews, SH Ramirez, ZK Khan, P Jain
    Sci Rep, 2017;7(1):2707.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
    Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
    J. Immunol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1
    Authors: J Yuzugulen, JA Douthwaite, EG Wood, IC Villar, NSA Patel, J Jegard, H Gaertner, I Rossitto-B, K Rose, O Hartley, PR Cutillas, A Ahluwalia, R Corder
    Sci Rep, 2017;7(1):4956.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  230. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
    Authors: KJ Chung, A Chatzigeor, M Economopou, R Garcia-Mar, VI Alexaki, I Mitroulis, M Nati, J Gebler, T Ziemssen, SE Goelz, J Phieler, JH Lim, KP Karalis, T Papayannop, M Blüher, G Hajishenga, T Chavakis
    Nat. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  231. Oncolytic Adenoviruses Armed with Tumor Necrosis Factor Alpha and Interleukin-2 Enable Successful Adoptive Cell Therapy
    Authors: R Havunen, M Siurala, S Sorsa, S Grönberg-V, M Behr, S Tähtinen, JM Santos, P Karell, J Rusanen, DM Nettelbeck, A Ehrhardt, A Kanerva, A Hemminki
    Mol Ther Oncolytics, 2017;4(0):77-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  232. Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
    Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill,, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
    JCI Insight, 2017;2(17):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  233. TNF? promotes proliferation of human synovial MSCs while maintaining chondrogenic potential
    Authors: M Shioda, T Muneta, K Tsuji, M Mizuno, K Komori, H Koga, I Sekiya
    PLoS ONE, 2017;12(5):e0177771.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Augmented Serum Amyloid A1/2 Mediated by TNF-induced NF-?B in Human Serous Ovarian Epithelial Tumors
    Authors: H Choi, RMC Ignacio, ES Lee, AJ Wilson, D Khabele, DS Son
    Immune Netw, 2017;17(2):121-127.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  235. RalBP1 and p19-VHL play an oncogenic role, and p30-VHL plays a tumor suppressor role during the blebbishield emergency program
    Authors: GG Jinesh, AM Kamat
    Cell Death Discov, 2017;3(0):17023.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  236. IFN-? and TNF-? synergism may provide a link between psoriasis and inflammatory atherogenesis
    Authors: NN Mehta, HL Teague, WR Swindell, Y Baumer, NL Ward, X Xing, B Baugous, A Johnston, AA Joshi, J Silverman, DH Barnes, L Wolterink, RP Nair, PE Stuart, M Playford, JJ Voorhees, MK Sarkar, JT Elder, K Gallagher, SK Ganesh, JE Gudjonsson
    Sci Rep, 2017;7(1):13831.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  237. A type of human skin dendritic cell marked by CD5 is associated with the development of inflammatory skin disease
    Authors: D Korenfeld, L Gorvel, A Munk, J Man, A Schaffer, T Tung, C Mann, E Klechevsky
    JCI Insight, 2017;2(18):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Ziziphus nummularia Inhibits Inflammation-Induced Atherogenic Phenotype of Human Aortic Smooth Muscle Cells
    Authors: M Fardoun, T Al-Shehabi, A El-Yazbi, K Issa, F Zouein, D Maaliki, R Iratni, AH Eid
    Oxid Med Cell Longev, 2017;2017(0):4134093.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  239. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
    Authors: Y Haim, M Blüher, D Konrad, N Goldstein, N Klöting, I Harman-Boe, B Kirshtein, D Ginsberg, T Tarnovscki, Y Gepner, I Shai, A Rudich
    Mol Metab, 2017;6(7):725-736.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  240. Synovial cell death is regulated by TNF-?-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1?
    Authors: JW Lee, J Lee, SH Um, EY Moon
    Cell Death Dis, 2017;8(4):e2727.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  241. Identification of a small molecule that primes the type I interferon response to cytosolic DNA
    Authors: S Khiar, M Lucas-Hour, S Nisole, N Smith, O Helynck, M Bourgine, C Ruffié, JP Herbeuval, H Munier-Leh, F Tangy, PO Vidalain
    Sci Rep, 2017;7(1):2561.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  242. Inhibition of 6-phosphofructo-2-kinase suppresses fibroblast-like synoviocytes- mediated synovial inflammation and joint destruction in rheumatoid arthritis
    Authors: Y Zou, S Zeng, M Huang, Q Qiu, Y Xiao, M Shi, Z Zhan, L Liang, X Yang, H Xu
    Br. J. Pharmacol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  243. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
    Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
    Autophagy, 2017;0(0):0.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  244. Suberoylanilide hydroxamic acid increases anti-cancer effect of tumor necrosis factor-? through up-regulation of TNF receptor 1 in lung cancer cells.
    Authors: Bo Ra You, Bo Ram Han, Woo Hyun Park
    Oncotarget, 2017;0(0):1949-2553.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Anti-Inflammatory Effects of OxPAPC Involve Endothelial Cell-Mediated Generation of LXA4.
    Authors: Yunbo Ke, Noureddine Zebda, Olga Oskolkova, Taras Afonyushk, Evgeny Berdyshev, Yufeng Tian, Fanyong Meng, Nicolene Sarich, Valery N Bochkov, Ji Ming Wang, Anna A Birukova, Konstantin G Birukov
    Circulation Research, 2017;0(0):1524-4571.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  246. Dendritic cells from rheumatoid arthritis patient peripheral blood induce Th17 cell differentiation via miR-363/Integrin ?v/TGF-? axis
    Authors: F Pan, H Xiang, J Yan, L Hong, L Zhang, Y Liu, X Feng, C Cai
    Scand. J. Immunol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  247. HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
    Authors: S Zhu, Q Zhang, X Sun, HJ Zeh, MT Lotze, R Kang, D Tang
    Cancer Res, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?
    Authors: JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, M Wittmann, M Stacey
    Proc. Natl. Acad. Sci. U.S.A, 2017;114(13):E2748-E2757.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  249. Vaccination targeting native receptors to enhance the function and proliferation of chimeric antigen receptor (CAR)-modified T cells
    Authors: M Tanaka, H Tashiro, B Omer, N Lapteva, J Ando, M Ngo, B Mehta, G Dotti, PR Kinchingto, AM Leen, C Rossig, CM Rooney
    Clin. Cancer Res, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis
    Authors: J Retzlaff, K Thamm, CC Ghosh, W Ziegler, H Haller, SM Parikh, S David
    Sci Rep, 2017;7(0):44113.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  251. HAT1 induces lung cancer cell apoptosis via up regulating Fas
    Authors: N Han, L Shi, Q Guo, W Sun, Y Yu, L Yang, X Zhang, M Zhang
    Oncotarget, 2017;8(52):89970-89977.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  252. Identificaiton of Novel Immunogenic Human Papillomavirus Type 16 E7-Specific Epitopes Restricted to HLA-A*33;03 for Cervical Cancer Immunotherapy
    Authors: Jong Baeck Lim
    Yonsei Med. J., 2017;58(1):43-50.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  253. Inhibition of the Receptor Tyrosine Kinase AXL Restores Paclitaxel Chemosensitivity in Uterine Serous Cancer
    Authors: ML Palisoul, JM Quinn, E Schepers, IS Hagemann, L Guo, K Reger, AR Hagemann, CK McCourt, PH Thaker, MA Powell, DG Mutch, KC Fuh
    Mol. Cancer Ther., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  254. Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
    Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
    Stem Cell Res Ther, 2017;8(1):79.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  255. Frontline Science: c-Myc regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection
    Authors: R Connor, LD Jones, X Qiu, J Thakar, SB Maggirwar
    J. Leukoc. Biol., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  256. Role of calcium in regulating the intra- and extracellular cleavage of von Willebrand factor by the protease ADAMTS13
    Authors: S Gogia, A Kelkar, C Zhang, KM Dayananda, S Neelamegha
    Blood Adv, 2017;1(23):2063-2074.
    Applications: Western Blot
  257. Metabolic Adaptation Establishes Disease Tolerance to Sepsis
    Authors: S Weis, AR Carlos, MR Moita, S Singh, B Blankenhau, S Cardoso, R Larsen, S Rebelo, S Schäuble, L Del Barrio, G Mithieux, F Rajas, S Lindig, M Bauer, MP Soares
    Cell, 2017;169(7):1263-1275.e14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  258. CXorf48 is a potential therapeutic target for achieving treatment-free remission in CML patients
    Authors: M Matsushita, K Ozawa, T Suzuki, M Nakamura, N Nakano, S Kanchi, D Ichikawa, E Matsuki, M Sakurai, D Karigane, H Kasahara, N Tsukamoto, T Shimizu, T Mori, H Nakajima, S Okamoto, Y Kawakami, Y Hattori
    Blood Cancer J, 2017;7(9):e601.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
    Authors: M Frank-Bert, M Trenkmann, K Klein, E Karouzakis, H Rehrauer, A Bratus, C Kolling, M Armaka, A Filer, BA Michel, RE Gay, CD Buckley, G Kollias, S Gay, C Ospelt
    Nat Commun, 2017;8(0):14852.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Identification of benzazole compounds that induce HIV-1 transcription
    Authors: JD Graci, D Michaels, G Chen, GM Schiralli, S Nodder, M Weetall, GM Karp, Z Gu, JM Colacino, AJ Henderson
    PLoS ONE, 2017;12(6):e0179100.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology
    Authors: M Silva, RK Fung, CB Donnelly, PA Videira, R Sackstein
    J. Immunol, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  262. Diosgenin, an Activator of 1,25D3-MARRS Receptor/ERp57, Attenuates the Effects of TNF-? by Causing ADAM10-Dependent Ectodomain Shedding of TNF Receptor 1
    Authors: WS Yang, SY Moon, MJ Lee, EK Lee, SK Park
    Cell. Physiol. Biochem., 2017;43(6):2434-2445.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  263. Apomorphine suppresses TNF-?-induced MMP-9 expression and cell invasion through inhibition of ERK/AP-1 signaling pathway in MCF-7 cells
    Authors: YS Jung, SO Lee
    Biochem. Biophys. Res. Commun., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  264. MicroRNA-155 induction via TNF-? and IFN-? suppresses expression of programmed death ligand-1 (PD-L1) in human primary cells
    Authors: D Yee, KM Shah, MC Coles, TV Sharp, D Lagos
    J. Biol. Chem., 2017;292(50):20683-20693.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  265. Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching
    Authors: R Ahmad, B Rah, D Bastola, P Dhawan, AB Singh
    Sci Rep, 2017;7(1):5125.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  266. Adipogenic differentiation of MSC alters their immunomodulatory properties in a tissue-specific manner
    Authors: H Munir, LS Ward, L Sheriff, S Kemble, S Nayar, F Barone, GB Nash, HM McGettrick
    Stem Cells, 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  267. ST6Gal-I sialyltransferase promotes tumor necrosis factor (TNF)-mediated cancer cell survival via sialylation of the TNF receptor 1 (TNFR1) death receptor
    Authors: AT Holdbrooks, CM Britain, SL Bellis
    J. Biol. Chem., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  268. Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-?B-Activating Factors through Direct Downregulation of IKK? and IKK?
    Authors: MH Hancock, LM Hook, J Mitchell, JA Nelson
    MBio, 2017;8(2):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  269. A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors
    Authors: A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti
    JCI Insight, 2017;2(12):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Regression of apoptosis-resistant colorectal tumors by induction of necroptosis in mice
    Authors: GW He, C Günther, V Thonn, YQ Yu, E Martini, B Buchen, MF Neurath, M Stürzl, C Becker
    J. Exp. Med., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  271. Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
    Authors: N Starc, D Ingo, A Conforti, V Rossella, L Tomao, A Pitisci, F De Mattia, I Brigida, M Algeri, M Montanari, G Palumbo, P Merli, P Rossi, A Aiuti, F Locatelli, ME Bernardo
    Sci Rep, 2017;7(1):8153.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  272. Long noncoding RNA NEAT1 promotes nasopharyngeal carcinoma progression through regulation of miR-124/NF-?B pathway
    Authors: N Cheng, Y Guo
    Onco Targets Ther, 2017;10(0):5843-5853.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  273. Ligand-activated epidermal growth factor receptor (EGFR) signaling governs endocytic trafficking of unliganded receptor monomers by non-canonical phosphorylation
    Authors: T Tanaka, Y Zhou, T Ozawa, R Okizono, A Banba, T Yamamura, E Oga, A Muraguchi, H Sakurai
    J. Biol. Chem., 2017;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  274. Analytical ultracentrifugation with fluorescence detection system reveals differences in complex formation between recombinant human TNF and different biological TNF antagonists in various environments
    Authors: E Krayukhina, M Noda, K Ishii, T Maruno, H Wakabayash, M Tada, T Suzuki, A Ishii-Wata, M Kato, S Uchiyama
    MAbs, 2017;9(4):664-679.
    Applications: Bioassay
  275. Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.
    Authors: Divakar S, Ramana Reddy M, Cosenza S, Baker S, Perumal D, Antonelli A, Brody J, Akula B, Parekh S, Premkumar Reddy E
    Leukemia, 2016;30(1):86-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  276. Endothelial Cell Activation is Regulated by Epidermal Growth Factor-Like Domain 7 (Egfl7) during Inflammation
    J Biol Chem, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  277. Endothelial Surface Protrusion by a Point Force
    Authors: Y Chen, L Lu, JY Shao
    Biophys. J, 2016;110(5):1150-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  278. IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  279. A Common Genetic Variant in TLR1 Enhances Human Neutrophil Priming and Impacts Length of Intensive Care Stay in Pediatric Sepsis.
    Authors: Whitmore L, Hook J, Philiph A, Hilkin B, Bing X, Ahn C, Wong H, Ferguson P, Moreland J
    J Immunol, 2016;196(3):1376-86.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  280. Interferon-? and Tumor Necrosis Factor-? Polarize Bone Marrow Stromal Cells Uniformly to a Th1 Phenotype
    Sci Rep, 2016;6(0):26345.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  281. Bioequivalence, safety and immunogenicity of BI 695501, an adalimumab biosimilar candidate, compared with the reference biologic in a randomized, double-blind, active-comparator Phase I clinical study (VOLTAIRE�-PK) in healthy subjects
    Authors: Niklas Czeloth
    Expert Opin Investig Drugs, 2016;0(0):.
    Applications: Bioassay
  282. Dendritic Cell-Secreted Cytotoxic T-Lymphocyte-Associated Protein-4 Regulates the T-cell Response by Downmodulating Bystander Surface B7
    Authors: MM Halpert, V Konduri, D Liang, Y Chen, JB Wing, S Paust, JM Levitt, WK Decker
    Stem Cells Dev., 2016;25(10):774-87.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Regulation and function of Bone Morphogenetic Protein signaling in colonic injury and inflammation
    Authors: Andrea Todisco
    Am. J. Physiol. Gastrointest. Liver Physiol., 2016;0(0):ajpgi.00169.2.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study
    Authors: O Freynet, J Marchal-So, F Jean-Louis, A Mailleux, B Crestani, P Soler, L Michel
    Respir Res, 2016;17(1):36.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  285. Negative regulation of NF-?B p65 activity by serine 536 phosphorylation.
    Authors: Jean-Philippe Pradère, Céline Hernandez, Christiane Koppe, Richard A Friedman, Tom Luedde, Robert F Schwabe
    Science Signaling, 2016;0(0):1937-9145.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  286. HDL function is impaired in acute myocardial infarction independent of plasma HDL cholesterol levels
    Authors: Wijtske Annema
    J Clin Lipidol, 2016;10(6):1318-1328.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  287. Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling
    Sci Rep, 2016;6(0):39190.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  288. Cytokines TNF-?, IL-6, IL-17F, and IL-4 Differentially Affect Osteogenic Differentiation of Human Adipose Stem Cells.
    Authors: Angela P Bastidas-C, Astrid D Bakker, Behrouz Zandieh-D, Cornelis J Kleverlaa, Nathalie Bravenboe, Tim Forouzanf, Jenneke Klein-Nul
    Stem Cells International, 2016;0(0):1687-966X.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  289. Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
    Nat Commun, 2016;7(0):12951.
    Species: Ovine
    Sample Types: Whole Tissue
    Applications: Bioassay
  290. Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
    Authors: R Yosef, N Pilpel, R Tokarsky-A, A Biran, Y Ovadya, S Cohen, E Vadai, L Dassa, E Shahar, R Condiotti, I Ben-Porath, V Krizhanovs
    Nat Commun, 2016;7(0):11190.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  291. Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17
    PLoS ONE, 2016;11(9):e0161759.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  292. Role for the MED21-MED7 Hinge in Assembly of the Mediator-RNA Polymerase II Holoenzyme
    Authors: Joan W Conaway
    J. Biol. Chem., 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  293. Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement
    Authors: Michael A Schmid
    PLoS Pathog, 2016;12(6):e1005676.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  294. Selective IRAK4 Inhibition Attenuates Disease in Murine Lupus Models and Demonstrates Steroid Sparing Activity
    Authors: Shailesh Dudhgaonka
    J. Immunol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex.
    Authors: Guo Z, Zheng L, Liao X, Geller D
    PLoS ONE, 2016;11(1):e0146640.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  296. Bradykinin stimulates protein kinase D-mediated colonic myofibroblast migration via cyclooxygenase-2 and heat shock protein 27
    Authors: Eric Chu
    J. Surg. Res, 2016;209(0):191-198.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  297. The Analysis of CD83 Expression on Human Immune Cells Identifies a Unique CD83+-Activated T Cell Population
    Authors: Derek N J Hart
    J. Immunol., 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Anti-inflammatory treatment improves high-density lipoprotein function in rheumatoid arthritis
    Authors: John Deanfield
    Heart, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis
    Cell Death Dis, 2016;7(6):e2287.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  300. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    Cell, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  301. Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells
    PLoS ONE, 2016;11(5):e0156145.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  302. Ticagrelor, but not clopidogrel, reduces arterial thrombosis via endothelial tissue factor suppression
    Authors: Martin F Reiner
    Cardiovasc. Res, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  303. Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis.
    Authors: Lu W, Sun J, Yoon J, Zhang Y, Zheng L, Murphy E, Mattson M, Lenardo M
    PLoS ONE, 2016;11(1):e0147792.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  304. Extracellular Microvesicle Production by Human Eosinophils Activated by Inflammatory Stimuli
    Authors: Rossana C N Melo
    Front Cell Dev Biol, 2016;4(0):117.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Environmental factor and inflammation-driven alteration of the total peripheral T-cell compartment in granulomatosis with polyangiitis
    Authors: Anja Kerstein
    J. Autoimmun, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  306. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency
    Proc. Natl. Acad. Sci. U.S.A, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells
    PLoS ONE, 2016;11(12):e0167361.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  308. MMP8 Is Increased in Lesions and Blood of Acne Inversa Patients: A Potential Link to Skin Destruction and Metabolic Alterations
    Authors: Robert Sabat
    Mediators Inflamm., 2016;2016(0):4097574.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  309. IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling
    Authors: R Liu, C Tang, A Shen, H Luo, X Wei, D Zheng, C Sun, Z Li, D Zhu, T Li, Z Wu
    Oncotarget, 2016;7(51):85079-85096.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Adsorption as a Contributor for Inflammatory Mediators Removal by Different Hemofiltration Membranes: A Pilot Study
    Authors: Benjamin Malard
    Artif Organs, 2016;0(0):.
    Species: Human
    Sample Types: Plasma
    Applications: Hemofiltration Procedure
  311. Anti-inflammatory and immunomodulatory effects of Aquaphilus dolomiae extract on in vitro models
    Authors: Nathalie Castex-Riz
    Clin Cosmet Investig Dermatol, 2016;9(0):421-434.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  312. IRAK1, a Target of miR-146b, Reduces Cell Aggressiveness of Human Papillary Thyroid Carcinoma
    J Clin Endocrinol Metab, 2016;0(0):jc20162276.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease
    Sci Rep, 2016;6(0):35282.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Roflumilast N-oxide in Combination with Formoterol Enhances the Anti-inflammatory Effect of Dexamethasone in ASM Cells
    Authors: Brijeshkumar S Patel
    Am. J. Respir. Cell Mol. Biol, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Mycobacterium massiliense Induces Macrophage Extracellular Traps with Facilitating Bacterial Growth
    PLoS ONE, 2016;11(5):e0155685.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization
    Mol Ther Methods Clin Dev, 2016;3(0):16056.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells
    Invest. Ophthalmol. Vis. Sci, 2016;57(15):6482-6495.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  318. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor ?1 expression
    Stem Cell Res Ther, 2016;7(1):175.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  319. Facile supermolecular aptamer inhibitors of L-selectin.
    Authors: Chang, Elizabet, Eckert, Mark A, Ali, M Monsur, Riazifar, Hamidrez, Pone, Egest J, Liu, Linan, Zhao, Weian
    PLoS ONE, 2015;10(3):e0123034.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Nuclear FAM21 participates in NF-kappaB-dependent gene regulation in pancreatic cancer cells.
    Authors: Deng Z, Gomez T, Osborne D, Phillips-Krawczak C, Zhang J, Billadeau D
    J Cell Sci, 2015;128(2):373-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  321. Role of transforming growth factor-activated kinase-1 on tumor necrosis factor-alpha actions in human adipose tissue-derived stromal cells.
    Authors: Lee S, Lee J, Shin K, Kim D, Kim Y, Bae Y, Jung J
    Stem Cells Dev, 2015;24(7):836-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  322. Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage.
    Authors: Catanzaro D, Rancan S, Orso G, Dall'Acqua S, Brun P, Giron M, Carrara M, Castagliuolo I, Ragazzi E, Caparrotta L, Montopoli M
    PLoS ONE, 2015;10(5):e0125375.
  323. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.
    Authors: Watson R, Buck J, Levin L, Winger R, Wang J, Arase H, Muller W
    J Exp Med, 2015;212(7):1021-41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  324. The effect of protease inhibitors on the induction of osteoarthritis-related biomarkers in bovine full-depth cartilage explants.
    Authors: He Y, Zheng Q, Jiang M, Sun S, Christiansen T, Kassem M, Karsdal M, Bay-Jensen A
    PLoS ONE, 2015;10(0):.
    Species: Bovine
    Sample Types: Whole Tissue
    Applications: Bioassay
  325. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
    Authors: Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M
    Invest Ophthalmol Vis Sci, 2015;56(2):1051-62.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  326. Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome.
    Authors: Fairclough L, Stoop A, Negm O, Radford P, Tighe P, Todd I
    Eur J Immunol, 2015;45(10):2937-44.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  327. Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma.
    Authors: Yousef S, Heise J, Lajmi N, Bartels K, Kroger N, Luetkens T, Atanackovic D
    J Transl Med, 2015;13(0):197.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Anti-apoptotic NF-kappaB and "gain of function" mutp53 in concert act pro-apoptotic in response to UVB+IL-1 via enhanced TNF production.
    Authors: Muller I, Beissert S, Kulms D
    J Invest Dermatol, 2015;135(3):851-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
    Authors: Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, Schaeren-Wiemers N, Du Pasquier R
    J Neuroinflammation, 2015;12(0):119.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Molecular mechanisms linking high dose medroxyprogesterone with HIV-1 risk.
    Authors: Irvin S, Herold B
    PLoS ONE, 2015;10(3):e0121135.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  331. Oncogenic Transformation Can Orchestrate Immune Evasion and Inflammation in Human Mesenchymal Stem Cells Independently of Extrinsic Immune-Selective Pressure.
    Authors: Miranda A, Funes J, Sanchez N, Limia C, Mesa M, Quezada S, Perez R, de Leon J
    Cancer Res, 2015;75(15):3032-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  332. CYLD and the NEMO Zinc Finger Regulate Tumor Necrosis Factor Signaling and Early Embryogenesis.
    Authors: Zhao Y, Ma C, Wu L, Iwai K, Ashwell J, Oltz E, Ballard D, Jain A
    J Biol Chem, 2015;290(36):22076-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  333. RelB/p50 complexes regulate cytokine-induced YKL-40 expression.
    Authors: Bhardwaj R, Yester J, Singh S, Biswas D, Surace M, Waters M, Hauser K, Yao Z, Boyce B, Kordula T
    J Immunol, 2015;194(6):2862-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  334. Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment.
    Authors: Rousseau M, Belleannee C, Duchez A, Cloutier N, Levesque T, Jacques F, Perron J, Nigrovic P, Dieude M, Hebert M, Gelb M, Boilard E
    PLoS ONE, 2015;10(1):e0116812.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  335. L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro.
    Authors: Rzeniewicz K, Newe A, Rey Gallardo A, Davies J, Holt M, Patel A, Charras G, Stramer B, Molenaar C, Tedder T, Parsons M, Ivetic A
    Proc Natl Acad Sci U S A, 2015;112(12):E1461-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  336. Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function.
    Authors: Leslie J, Huang S, Opp J, Nagy M, Kobayashi M, Young V, Spence J
    Infect Immun, 2015;83(1):138-45.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  337. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor kappaB (NF-kappaB) signaling.
    Authors: Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, Zhang Y, Guo S, Qin X, Li T, Li W, Li A, Zhang X, Li H
    J Biol Chem, 2015;290(16):10395-405.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  338. RIP1 Kinase Is an Oncogenic Driver in Melanoma.
    Authors: Liu X, Lai F, Yan X, Jiang C, Guo S, Wang C, Croft A, Tseng H, Wilmott J, Scolyer R, Jin L, Zhang X
    Cancer Res, 2015;75(8):1736-48.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  339. Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.
    Authors: Boisson B, Laplantine E, Dobbs K, Cobat A, Tarantino N, Hazen M, Lidov H, Hopkins G, DU L, Belkadi A, Chrabieh M, Itan Y, Picard C, Fournet J, Eibel H, Tsitsikov E, Pai S, Abel L, Al-Herz W, Casanova J, Israel A, Notarangelo L
    J Exp Med, 2015;212(6):939-51.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  340. Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes.
    Authors: Sommerfelt R, Feuerherm A, Skuland T, Johansen B
    PLoS ONE, 2015;10(4):e0119088.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  341. Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
    Authors: Lam, Sharon, Sung, Julia, Cruz, Conrad, Castillo-Caro, Paul, Ngo, Minhtran, Garrido, Carolina, Kuruc, Joann, Archin, Nancie, Rooney, Cliona, Margolis, David, Bollard, Catherin
    Mol Ther, 2015;23(2):387-95.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  342. The cerebral cavernous malformation 3 gene is necessary for senescence induction.
    Authors: Guerrero A, Iglesias C, Raguz S, Floridia E, Gil J, Pombo C, Zalvide J
    Aging Cell, 2015;14(2):274-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  343. Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting beta(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligands.
    Authors: Rider C, Shah S, Miller-Larsson A, Giembycz M, Newton R
    PLoS ONE, 2015;10(1):e0116773.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  344. BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak-STAT signaling in a gene-specific manner in human monocytes.
    Authors: Chan C, Fang C, Qiao Y, Yarilina A, Prinjha R, Ivashkiv L
    Eur J Immunol, 2015;45(1):287-97.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  345. PHLDA1 expression is controlled by an estrogen receptor-NFkappaB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres.
    Authors: Kastrati I, Canestrari E, Frasor J
    Oncogene, 2015;34(18):2309-16.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  346. Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein delta.
    Authors: Yamaguchi J, Tanaka T, Eto N, Nangaku M
    Kidney Int, 2015;88(2):262-75.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  347. IL-4 Downregulates IL-1beta and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine.
    Authors: Onderdijk A, Baerveldt E, Kurek D, Kant M, Florencia E, Debets R, Prens E
    J Immunol, 2015;195(4):1744-52.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  348. Th17-type cytokines, IL-6 and TNF-alpha synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.
    Authors: De Simone V, Franze E, Ronchetti G, Colantoni A, Fantini M, Di Fusco D, Sica G, Sileri P, MacDonald T, Pallone F, Monteleone G, Stolfi C
    Oncogene, 2015;34(27):3493-503.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  349. 6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NFkappaB activation in airway epithelial cells.
    Authors: Kurakula K, Hamers A, van Loenen P, de Vries C
    Respir Res, 2015;16(0):73.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  350. Tissue Inhibitor of Metalloproteinase-4 Triggers Apoptosis in Cervical Cancer Cells.
    Authors: Lizarraga F, Ceballos-Cancino G, Espinosa M, Vazquez-Santillan K, Maldonado V, Melendez-Zajgla J
    PLoS ONE, 2015;10(8):e0135929.
  351. Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.
    Authors: Singer B, Opp L, Heinrich A, Schreiber F, Binding-Liermann R, Berrocal-Almanza L, Heyl K, Muller M, Weimann A, Zweigner J, Slevogt H
    PLoS ONE, 2014;9(4):e94106.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  352. Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal.
    Authors: Salzano S, Checconi P, Hanschmann E, Lillig C, Bowler L, Chan P, Vaudry D, Mengozzi M, Coppo L, Sacre S, Atkuri K, Sahaf B, Herzenberg L, Herzenberg L, Mullen L, Ghezzi P
    Proc Natl Acad Sci U S A, 2014;111(33):12157-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  353. Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential.
    Authors: Cubbon R, Yuldasheva N, Viswambharan H, Mercer B, Baliga V, Stephen S, Askham J, Sukumar P, Skromna A, Mughal R, Walker A, Bruns A, Bailey M, Galloway S, Imrie H, Gage M, Rakobowchuk M, Li J, Porter K, Ponnambalam S, Wheatcroft S, Beech D, Kearney M
    Stem Cells, 2014;32(10):2714-23.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  354. A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells.
    Authors: Ugarte-Berzal E, Bailon E, Amigo-Jimenez I, Albar J, Garcia-Marco J, Garcia-Pardo A
    J Biol Chem, 2014;289(22):15340-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  355. Endothelial activation by platelets from sickle cell anemia patients.
    Authors: Proenca-Ferreira R, Brugnerotto A, Garrido V, Dominical V, Vital D, Ribeiro M, dos Santos M, Traina F, Olalla-Saad S, Costa F, Conran N
    PLoS ONE, 2014;9(2):e89012.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  356. IL-2 phosphorylates STAT5 to drive IFN-gamma production and activation of human dendritic cells.
    Authors: Herr F, Lemoine R, Gouilleux F, Meley D, Kazma I, Heraud A, Velge-Roussel F, Baron C, Lebranchu Y
    J Immunol, 2014;192(12):5660-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  357. Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death.
    Authors: Ji, Weidong, Yang, Mei, Praggastis, Alexandr, Li, Yonghao, Zhou, Huanjiao, He, Yun, Ghazvinian, Roxanne, Cincotta, Dylan J, Rice, Kevin P, Min, Wang
    PLoS ONE, 2014;9(7):e103224.
    Species: Bovine
    Sample Types: Whole Cells
    Applications: Bioassay
  358. Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels.
    Authors: You B, Park W
    Int J Oncol, 2014;44(5):1745-55.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  359. Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis.
    Authors: Dalli, Jesmond, Norling, Lucy V, Montero-Melendez, Trinidad, Federici Canova, Donata, Lashin, Hazem, Pavlov, Anton M, Sukhorukov, Gleb B, Hinds, Charles, Perretti, Mauro
    EMBO Mol Med, 2014;6(1):27-42.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  360. Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation.
    Authors: Mambetsariev I, Tian Y, Wu T, Lavoie T, Solway J, Birukov K, Birukova A
    PLoS ONE, 2014;9(4):e92670.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  361. A splicing variant of NME1 negatively regulates NF-kappaB signaling and inhibits cancer metastasis by interacting with IKKbeta.
    Authors: You D, Park C, Lee H, Moon M, Kang J, Lee C, Oh S, Ahn C, Seong J, Hwang J
    J Biol Chem, 2014;289(25):17709-20.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  362. Rad GTPase inhibits the NFkappaB pathway through interacting with RelA/p65 to impede its DNA binding and target gene transactivation.
    Authors: Hsiao B, Chang T, Wu I, Chen M
    Cell Signal, 2014;26(7):1437-44.
  363. Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer.
    Authors: Kim S, Chung H, Lee K, Lim J
    J Transl Med, 2014;12(0):229.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  364. TRAIL/DR5 signaling promotes macrophage foam cell formation by modulating scavenger receptor expression.
    Authors: Liu F, Wu X, Zhang Y, Wang Y, Jiang F
    PLoS ONE, 2014;9(1):e87059.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  365. Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.
    Authors: Ohlsson S, Ohlsson S, Soderberg D, Gunnarsson L, Pettersson A, Segelmark M, Hellmark T
    Clin Exp Immunol, 2014;176(3):363-72.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  366. The in vitro pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long acting beta2-adrenoceptor agonist.
    Authors: Tannheimer S, Sorensen E, Cui Z, Kim M, Patel L, Baker W, Phillips G, Wright C, Salmon M
    J Pharmacol Exp Ther, 2014;349(1):85-93.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  367. MicroRNA-26b suppresses the NF-kappaB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3.
    Authors: Zhao N, Wang R, Zhou L, Zhu Y, Gong J, Zhuang S
    Mol Cancer, 2014;13(0):35.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  368. Tumour necrosis factor-alpha regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-kappaB and AP-1.
    Authors: Kankaanranta H, Ilmarinen P, Zhang X, Adcock I, Lahti A, Barnes P, Giembycz M, Lindsay M, Moilanen E
    PLoS ONE, 2014;9(2):e90298.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  369. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.
    Authors: Bailon E, Ugarte-Berzal E, Amigo-Jimenez I, Van den Steen P, Opdenakker G, Garcia-Marco J, Garcia-Pardo A
    J Leukoc Biol, 2014;96(2):185-99.
    Species: Human
    Sample Types: N/A
    Applications: Not Specified
  370. Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways.
    Authors: Chiang, En-Pei I, Tsai, Shu-Yao, Kuo, Yueh-Hsi, Pai, Man-Hui, Chiu, Hsi-Lin, Rodriguez, Raymond, Tang, Feng-Yao
    PLoS ONE, 2014;9(6):e99631.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  371. Glucocorticoid-induced reversal of interleukin-1beta-stimulated inflammatory gene expression in human oviductal cells.
    Authors: Backman S, Kollara A, Haw R, Stein L, Brown T
    PLoS ONE, 2014;9(5):e97997.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  372. Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk.
    Authors: Sehgal K, Ragheb R, Fahmy T, Dhodapkar M, Dhodapkar K
    J Immunol, 2014;193(5):2297-305.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  373. Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis.
    Authors: Volpe E, Pattarini L, Martinez-Cingolani C, Meller S, Donnadieu M, Bogiatzi S, Fernandez M, Touzot M, Bichet J, Reyal F, Paronetto M, Chiricozzi A, Chimenti S, Nasorri F, Cavani A, Kislat A, Homey B, Soumelis V
    J Allergy Clin Immunol, 2014;134(2):373-81.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  374. Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-alpha-induced procoagulant activity and apoptosis in endothelial cells.
    Authors: Ohkawara H, Ishibashi T, Sugimoto K, Ikeda K, Ogawa K, Takeishi Y
    PLoS ONE, 2014;9(8):e105697.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  375. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.
    Authors: Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, Barra C, Comerma L, Chudnovskiy A, Gentile M, Llige D, Cols M, Serrano S, Arostegui J, Juan M, Yague J, Merad M, Fagarasan S, Cerutti A
    Nat Immunol, 2014;15(4):354-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  376. Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation.
    Authors: Sato J, Kinugasa M, Satomi-Kobayashi S, Hatakeyama K, Knox A, Asada Y, Wierman M, Hirata K, Rikitake Y
    PLoS ONE, 2014;9(9):e107236.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  377. Absence of a role for interleukin-13 in inflammatory bowel disease.
    Authors: Biancheri P, Di Sabatino A, Ammoscato F, Facciotti F, Caprioli F, Curciarello R, Hoque S, Ghanbari A, Joe-Njoku I, Giuffrida P, Rovedatti L, Geginat J, Corazza G, MacDonald T
    Eur J Immunol, 2014;44(2):370-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  378. Influence of proinflammatory stimuli on the expression of vascular ribonuclease 1 in endothelial cells.
    Authors: Gansler J, Preissner K, Fischer S
    FASEB J, 2014;28(2):752-60.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  379. Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition.
    Authors: Mimura N, Hideshima T, Shimomura T, Suzuki R, Ohguchi H, Rizq O, Kikuchi S, Yoshida Y, Cottini F, Jakubikova J, Cirstea D, Gorgun G, Minami J, Tai Y, Richardson P, Utsugi T, Iwama A, Anderson K
    Cancer Res, 2014;74(16):4458-69.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  380. Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M.
    Authors: Rabeony H, Petit-Paris I, Garnier J, Barrault C, Pedretti N, Guilloteau K, Jegou J, Guillet G, Huguier V, Lecron J, Bernard F, Morel F
    PLoS ONE, 2014;9(7):e101937.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  381. Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable pancreatic cancer.
    Authors: Shindo Y, Hazama S, Maeda Y, Matsui H, Iida M, Suzuki N, Yoshimura K, Ueno T, Yoshino S, Sakai K, Suehiro Y, Yamasaki T, Hinoda Y, Oka M
    J Transl Med, 2014;12(0):175.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  382. Interleukin-2 alters distribution of CD144 (VE-cadherin) in endothelial cells.
    Authors: Kim, Dae Won, Zloza, Andrew, Broucek, Joseph, Schenkel, Jason M, Ruby, Carl, Samaha, Georges, Kaufman, Howard L
    J Transl Med, 2014;12(0):113.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  383. p38-Mediated phosphorylation of Eps15 endocytic adaptor protein.
    Authors: Zhou Y, Tanaka T, Sugiyama N, Yokoyama S, Kawasaki Y, Sakuma T, Ishihama Y, Saiki I, Sakurai H
    FEBS Lett, 2014;588(1):131-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  384. A20 deficiency causes spontaneous neuroinflammation in mice.
    Authors: Guedes R, Csizmadia E, Moll H, Ma A, Ferran C, da Silva C
    J Neuroinflammation, 2014;11(0):122.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Stimulation
  385. Luteolin inhibits human keratinocyte activation and decreases NF-kappaB induction that is increased in psoriatic skin.
    Authors: Weng Z, Patel A, Vasiadi M, Therianou A, Theoharides T
    PLoS ONE, 2014;9(2):e90739.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  386. Novel ex vivo culture method for human monocytes uses shear flow to prevent total loss of transendothelial diapedesis function.
    Authors: Tsubota Y, Frey J, Raines E
    J Leukoc Biol, 2014;95(1):191-5.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  387. DeltaNp63 controls a TLR3-mediated mechanism that abundantly provides thymic stromal lymphopoietin in atopic dermatitis.
    Authors: Kubo T, Kamekura R, Kumagai A, Kawata K, Yamashita K, Mitsuhashi Y, Kojima T, Sugimoto K, Yoneta A, Sumikawa Y, Yamashita T, Sato N, Himi T, Ichimiya S
    PLoS ONE, 2014;9(8):e105498.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  388. Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis.
    Authors: Cucchiarini M, Madry H, Terwilliger E
    J Cell Mol Med, 2014;18(1):115-24.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  389. Transcriptional repression of the transforming growth factor beta (TGF-beta) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor kappaB (NF-kappaB) p50 enhances TGF-beta signaling in hepatic stellate cells.
    Authors: Liu C, Chen X, Yang L, Kisseleva T, Brenner D, Seki E
    J Biol Chem, 2014;289(10):7082-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  390. Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.
    Authors: Milwid, Jack M, Elman, Jessica, Li, Matthew, Shen, Keyue, Manrai, Arjun, Gabow, Aaron, Yarmush, Joshua, Jiao, Yunxin, Fletcher, Anne, Lee, Jungwoo, Cima, Michael, Yarmush, Martin L, Parekkadan, Biju
    Mol Ther, 2014;22(5):999-1007.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  391. Tumor necrosis factor (TNF)-alpha induction of CXCL10 in endothelial cells requires protein arginine methyltransferase 5 (PRMT5)-mediated nuclear factor (NF)-kappaB p65 methylation.
    Authors: Harris D, Bandyopadhyay S, Maxwell T, Willard B, DiCorleto P
    J Biol Chem, 2014;289(22):15328-39.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  392. Durable remission of renal cell carcinoma in conjuncture with graft versus host disease following allogeneic stem cell transplantation and donor lymphocyte infusion: rule or exception?
    Authors: van Bergen, Cornelis, Verdegaal, Elisabet, Honders, M Wilhel, Hoogstraten, Conny, Steijn-van Tol, A Q M Je, de Quartel, Linda, de Jong, Joan, Meyering, Maaike, Falkenburg, J H Fred, Griffioen, Marieke, Osanto, Susanne
    PLoS ONE, 2014;9(1):e85198.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  393. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
    Authors: Sidney L, Kirkham G, Buttery L
    Stem Cells Dev, 2014;23(6):605-17.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  394. Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, alpha-Ketoglutarate (alpha-KG), and DNA hydroxymethylation levels by interleukin-1beta in primary human chondrocytes.
    Authors: Haseeb A, Makki M, Haqqi T
    J Biol Chem, 2014;289(10):6877-85.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  395. Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity.
    Authors: Morlino G, Barreiro O, Baixauli F, Robles-Valero J, Gonzalez-Granado J, Villa-Bellosta R, Cuenca J, Sanchez-Sorzano C, Veiga E, Martin-Cofreces N, Sanchez-Madrid F
    Mol Cell Biol, 2014;34(8):1412-26.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  396. Characterization of platelet-monocyte complexes in HIV-1-infected individuals: possible role in HIV-associated neuroinflammation.
    Authors: Singh, Meera V, Davidson, Donna C, Jackson, Joseph W, Singh, Vir B, Silva, Jharon, Ramirez, Servio H, Maggirwar, Sanjay B
    J Immunol, 2014;192(10):4674-84.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  397. Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-alpha, and IL-1beta.
    Authors: Zhao Y, Xiao X, Frank S, Lin H, Xia Y
    Am J Physiol Endocrinol Metab, 2014;307(2):E186-98.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  398. CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis.
    Authors: Parlato M, Souza-Fonseca-Guimaraes F, Philippart F, Misset B, Adib-Conquy M, Cavaillon J
    J Immunol, 2014;192(5):2449-59.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  399. TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3.
    Authors: Hu M, Yang Q, Zhang J, Liu S, Zhang Y, Lin H, Huang Z, Wang Y, Zhang X, Zhong B, Shu H
    Proc Natl Acad Sci U S A, 2014;111(4):1509-14.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  400. TNF-alpha induces matrix metalloproteinase-9-dependent soluble intercellular adhesion molecule-1 release via TRAF2-mediated MAPKs and NF-kappaB activation in osteoblast-like MC3T3-E1 cells.
    Authors: Tsai C, Chen W, Hsieh H, Chi P, Hsiao L, Yang C
    J Biomed Sci, 2014;21(0):12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  401. Cell density impacts epigenetic regulation of cytokine-induced E-selectin gene expression in vascular endothelium.
    Authors: Hamada K, Osaka M, Yoshida M
    PLoS ONE, 2014;9(4):e90502.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  402. A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS).
    Authors: Negm O, Mannsperger H, McDermott E, Drewe E, Powell R, Todd I, Fairclough L, Tighe P
    Eur J Immunol, 2014;44(7):2096-110.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  403. Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy.
    Authors: Ahmad T, Mukherjee S, Pattnaik B, Kumar M, Singh S, Kumar M, Rehman R, Tiwari B, Jha K, Barhanpurkar A, Wani M, Roy S, Mabalirajan U, Ghosh B, Agrawal A
    EMBO J, 2014;33(9):994-1010.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  404. p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-kappaB subunit.
    Authors: O'Hara A, Simpson J, Morin P, Loveridge C, Williams A, Novo S, Stark L
    J Cell Sci, 2014;127(0):3659-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  405. MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
    Authors: Lopez-Ramirez M, Wu D, Pryce G, Simpson J, Reijerkerk A, King-Robson J, Kay O, de Vries H, Hirst M, Sharrack B, Baker D, Male D, Michael G, Romero I
    FASEB J, 2014;28(6):2551-65.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  406. IDO-independent suppression of T cell effector function by IFN-gamma-licensed human mesenchymal stromal cells.
    Authors: Chinnadurai R, Copland I, Patel S, Galipeau J
    J Immunol, 2014;192(4):1491-501.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  407. High activities of BACE1 in brains with mild cognitive impairment.
    Authors: Cheng X, He P, Lee T, Yao H, Li R, Shen Y
    Am J Pathol, 2014;184(1):141-7.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  408. Pharmacologic IKK/NF-kappaB inhibition causes antigen presenting cells to undergo TNFalpha dependent ROS-mediated programmed cell death.
    Authors: Tilstra J, Gaddy D, Zhao J, Dave S, Niedernhofer L, Plevy S, Robbins P
    Sci Rep, 2014;4(0):3631.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  409. A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.
    Authors: Lewis, Nuruddee, Patnaude, Lori A, Pelletier, Josephin, Souza, Donald J, Lukas, Susan M, King, F James, Hill, Jonathan, Stefanopoulos, Dimitria, Ryan, Kelli, Desai, Sudha, Skow, Donna, Kauschke, Stefan G, Broermann, Andre, Kuzmich, Daniel, Harcken, Christia, Hickey, Eugene R, Modis, Louise K
    PLoS ONE, 2014;9(6):e100883.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  410. Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.
    Authors: Suzuki, Hitoshi, Raska, Milan, Yamada, Koshi, Moldoveanu, Zina, Julian, Bruce A, Wyatt, Robert J, Tomino, Yasuhiko, Gharavi, Ali G, Novak, Jan
    J Biol Chem, 2014;289(8):5330-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  411. Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivation.
    Authors: Duverger, Alexandr, Wolschendorf, Frank, Anderson, Joshua C, Wagner, Frederic, Bosque, Alberto, Shishido, Takao, Jones, Jennifer, Planelles, Vicente, Willey, Christop, Cron, Randall, Kutsch, Olaf
    J Virol, 2014;88(1):364-76.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  412. TNF-alpha blockade induces IL-10 expression in human CD4+ T cells.
    Authors: Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L
    Nat Commun, 2014;5(0):3199.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  413. Toxoplasma gondii virulence factor ROP18 inhibits the host NF-kappaB pathway by promoting p65 degradation.
    Authors: Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J
    J Biol Chem, 2014;289(18):12578-92.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  414. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity.
    Authors: Schafer P, Parton A, Capone L, Cedzik D, Brady H, Evans J, Man H, Muller G, Stirling D, Chopra R
    Cell Signal, 2014;26(9):2016-29.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  415. Osteodifferentiated mesenchymal stem cells from bone marrow and adipose tissue express HLA-G and display immunomodulatory properties in HLA-mismatched settings: implications in bone repair therapy.
    Authors: Montespan F, Deschaseaux F, Sensebe L, Carosella E, Rouas-Freiss N
    J Immunol Res, 2014;2014(0):230346.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  416. Plasma cells in the mucosa of patients with inflammatory bowel disease produce granzyme B and possess cytotoxic activities.
    Authors: Cupi M, Sarra M, Marafini I, Monteleone I, Franze E, Ortenzi A, Colantoni A, Sica G, Sileri P, Rosado M, Carsetti R, MacDonald T, Pallone F, Monteleone G
    J Immunol, 2014;192(12):6083-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  417. Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB231 partly through suppression of the Akt pathway.
    Authors: Jin H, Lee W, Eun S, Jung J, Park H, Kim G, Choi Y, Ryu C, Jung J, Hong S, Shin S, Kim H
    Int J Oncol, 2014;45(4):1629-37.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  418. Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4.
    Authors: Catanzaro J, Sheshadri N, Pan J, Sun Y, Shi C, Li J, Powers R, Crawford H, Zong W
    Nat Commun, 2014;5(0):3729.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  419. Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members.
    Authors: Beigel F, Friedrich M, Probst C, Sotlar K, Goke B, Diegelmann J, Brand S
    PLoS ONE, 2014;9(4):e93498.
    Species: N/A
    Sample Types: N/A
    Applications: Western Blot
  420. The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.
    Authors: Lessey-Morillon E, Osborne L, Monaghan-Benson E, Guilluy C, O'Brien E, Superfine R, Burridge K
    J Immunol, 2014;192(7):3390-8.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  421. Overexpression of CCN3 inhibits inflammation and progression of atherosclerosis in apolipoprotein E-deficient mice.
    Authors: Liu J, Ren Y, Kang L, Zhang L
    PLoS ONE, 2014;9(4):e94912.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  422. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion.
    Authors: Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L
    PLoS ONE, 2014;9(9):e106673.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  423. Vaspin inhibits cytokine-induced nuclear factor-kappa B activation and adhesion molecule expression via AMP-activated protein kinase activation in vascular endothelial cells.
    Authors: Jung C, Lee M, Kang Y, Lee Y, Yoon H, Kang S, Lee W, Park J
    Cardiovasc Diabetol, 2014;13(0):41.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  424. Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD.
    Authors: Chattopadhyay A, Hood B, Conrads T, Redner R
    Mol Cancer Res, 2014;12(9):1283-91.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  425. Tumor necrosis factor stimulates osteoclastogenesis from human bone marrow cells under hypoxic conditions.
    Authors: Nomura T, Aoyama M, Waguri-Nagaya Y, Goto Y, Suzuki M, Miyazawa K, Asai K, Goto S
    Exp Cell Res, 2014;321(2):167-77.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  426. TNF-alpha induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways.
    Authors: Lo H, Lai T, Li C, Wu W
    Acta Pharmacol Sin, 2014;35(3):339-50.
  427. The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling.
    Authors: Wu L, Wang C, Boisson B, Misra S, Rayman P, Finke J, Puel A, Casanova J, Li X
    J Immunol, 2014;193(4):1590-9.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  428. A composite model of the human postcapillary venule for investigation of microvascular leukocyte recruitment.
    Authors: Lauridsen H, Pober J, Gonzalez A
    FASEB J, 2014;28(3):1166-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  429. Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids.
    Authors: Rahman M, Alkhouri H, Tang F, Che W, Ge Q, Ammit A
    PLoS ONE, 2014;9(3):e92466.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  430. Functional effects of Toll-like receptor (TLR)3, 7, 9, RIG-I and MDA-5 stimulation in nasal epithelial cells.
    Authors: Tengroth L, Millrud C, Kvarnhammar A, Kumlien Georen S, Latif L, Cardell L
    PLoS ONE, 2014;9(6):e98239.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  431. The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells.
    Authors: Fiorcari S, Brown W, McIntyre B, Estrov Z, Maffei R, O'Brien S, Sivina M, Hoellenriegel J, Wierda W, Keating M, Ding W, Kay N, Lannutti B, Marasca R, Burger J
    PLoS ONE, 2013;8(12):e83830.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  432. Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18.
    Authors: Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, Tanaka Y, Okamura H
    PLoS ONE, 2013;8(12):e82586.
    Species: Human
    Sample Types: N/A
    Applications: Not Specified
  433. Integration and regression of implanted engineered human vascular networks during deep wound healing.
    Authors: Hanjaya-Putra D, Shen Y, Wilson A, Fox-Talbot K, Khetan S, Burdick J, Steenbergen C, Gerecht S
    Stem Cells Transl Med, 2013;2(4):297-306.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  434. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics.
    Authors: Rapicavoli N, Qu K, Zhang J, Mikhail M, Laberge R, Chang H
    Elife, 2013;2(0):e00762.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  435. IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.
    Authors: Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, Behar S
    J Immunol, 2013;190(8):4196-204.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  436. Role and regulation of PDGFRalpha signaling in liver development and regeneration.
    Authors: Awuah P, Nejak-Bowen K, Monga S
    Am J Pathol, 2013;182(5):1648-58.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  437. Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes.
    Authors: Sommerfelt R, Feuerherm A, Jones K, Johansen B
    PLoS ONE, 2013;8(12):e83555.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  438. In vivo modulation of the inflammatory response by nonsteroidal antiinflammatory drug-related compounds that trigger L-selectin shedding.
    Authors: Herrera-Garcia A, Dominguez-Luis M, Arce-Franco M, Lopez-Fernandez J, Feria M, Barreiro O, Sanchez-Madrid F, Diaz-Gonzalez F
    Eur J Immunol, 2013;43(1):55-64.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  439. 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.
    Authors: Mabalirajan U, Rehman R, Ahmad T, Kumar S, Leishangthem G, Singh S, Dinda A, Biswal S, Agrawal A, Ghosh B
    Sci Rep, 2013;3(0):1540.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  440. Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration.
    Authors: Rossi E, Sanz-Rodriguez F, Eleno N, Duwell A, Blanco F, Langa C, Botella L, Cabanas C, Lopez-Novoa J, Bernabeu C
    Blood, 2013;121(2):403-15.
  441. Interferon-beta induces distinct gene expression response patterns in human monocytes versus T cells.
    Authors: Henig N, Avidan N, Mandel I, Staun-Ram E, Ginzburg E, Paperna T, Pinter R, Miller A
    PLoS ONE, 2013;8(4):e62366.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  442. Outer membrane vesicles derived from Escherichia coli up-regulate expression of endothelial cell adhesion molecules in vitro and in vivo.
    Authors: Kim J, Yoon Y, Lee J, Choi E, Yi N, Park K, Park J, Lotvall J, Kim Y, Gho Y
    PLoS ONE, 2013;8(3):e59276.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  443. The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytes.
    Authors: Mercier S, Donaghy H, Botting R, Turville S, Harman A, Nasr N, Ji H, Kusebauch U, Mendoza L, Shteynberg D, Sandgren K, Simpson R, Moritz R, Cunningham A
    PLoS Pathog, 2013;9(10):e1003700.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  444. NF-kappaB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma.
    Authors: McFarland B, Hong S, Rajbhandari R, Twitty G, Gray G, Yu H, Benveniste E, Nozell S
    PLoS ONE, 2013;8(11):e78728.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture
  445. Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
    Authors: Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M
    J Exp Med, 2013;211(2):263-80.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  446. Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice.
    Authors: Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R
    J Biol Chem, 2013;288(3):1953-66.
    Species: Human
    Sample Types: Whole Cells
    Applications: Cell Culture