Recombinant Human TNF-alpha Protein

(421 citations)
(16 Reviews)
  
  • Purity
    >97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
  • Endotoxin Level
    <0.10 EU per 1 μg of the protein by the LAL method.
  • Activity
    Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 221. The ED50 for this effect is 25-100 pg/mL.
    The specific activity of Recombinant Human TNF-alpha is approximately 7.6 x 104 IU/μg, which is calibrated against human TNF-alpha WHO International Standard (NIBSC code: 88/786).
  • Source
    E. coli-derived Val77-Leu233, with and without an N-terminal Met
  • Accession #
  • N-terminal Sequence
    Analysis
    Met & Val77
  • Predicted Molecular Mass
    17.5 kDa
  • SDS-PAGE
    17 kDa, reducing conditions
Carrier Free
What does CF mean?
CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.
What formulation is right for me?
In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.
210-TA
 
210-TA/CF
Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Data Images
Recombinant Human TNF-alpha (Catalog # 210‑TA) induces cytotoxicity in the L-929 mouse fibroblast cell line in the presence of the metabolic inhibitor actinomycin D. The ED50 for this effect is 25‑100 pg/mL.
1 µg/lane of Recombinant Human TNF-alpha was resolved by SDS-PAGE with silver staining, under reducing (R) conditions, showing a band at 17 kDa.
Background: TNF-alpha
Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (1, 2). Human TNF-alpha consisits of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 177 aa extracellular domain (ECD) (3). Within the ECD, human TNF-alpha shares 97% aa sequence identity with rhesus and 71%-92% with bovine, canine, cotton rat, equine, feline, mouse, porcine, and rat TNF-alpha. TNF-alpha is produced by a wide variety of immune, epithelial, endothelial, and tumor cells (1, 2). TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface (4). Cell surface TNF-alpha can induce the lysis of neighboring tumor cells and virus infected cells, and it can generate its own downstream cell signaling following ligation by soluble TNFR I (2, 5). Shedding of membrane bound TNF-alpha by TACE/ADAM17 releases the bioactive cytokine, a 55 kDa soluble trimer of the TNF-alpha extracellular domain (6-8). TNF-alpha binds the ubiquitous 55-60 kDa TNF RI (9, 10) and the hematopoietic cell-restricted 80 kDa TNF RII (11, 12), both of which are also expressed as homotrimers (1, 2, 13). Both type I and type II receptors bind TNF-alpha with comparable affinity (14), although only TNF RI contains a cytoplasmic death domain which triggers the activation of apoptosis. Soluble forms of both types of receptors are released and can neutralize the biological activity of TNF-alpha (15).
  • References:
    1. Zelova, H. and J. Hosek (2013) Inflamm. Res. 62:641.
    2. Juhasz, K. et al. (2013) Expert Rev. Clin. Immunol. 9:335.
    3. Pennica, D. et al. (1984) Nature 312:724.
    4. Tang, P. et al. (1996) Biochemistry 35:8216.
    5. Perez, C. et al. (1990) Cell 63:251.
    6. Black, R.A. et al. (1997) Nature 385:729.
    7. Moss, M.L. et al. (1997) Nature 385:733.
    8. Gearing, A.J.H. et al. (1994) Nature 370:555.
    9. Schall, T.J. et al. (1990) Cell 61:361.
    10. Loetscher, H. et al. (1990) Cell 61:351.
    11. Dembic, Z. et al. (1990) Cytokine 2:231.
    12. Smith, C.A. et al. (1990) Science 248:1019.
    13. Loetscher, H. et al. (1991) J. Biol. Chem. 266:18324.
    14. Pinckard, J.K. et al. (1997) J. Biol. Chem. 272:10784.
    15. Engelmann, H. et al. (1990) J. Biol. Chem. 265:1531.
  • Long Name:
    Tumor Necrosis Factor alpha
  • Entrez Gene IDs:
    7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
  • Alternate Names:
    APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; tnfa; tnf-a; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha
Related Research Areas
Citations:

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

421 Citations: Showing 1 - 10
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Applications
Sample Type
  1. Autophagy gene ATG7 regulates ultraviolet radiation-induced inflammation and skin tumorigenesis
    Authors: L Qiang, A Sample, CR Shea, K Soltani, KF Macleod, YY He
    Autophagy, 2017;0(0):0.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  2. Human Cytomegalovirus MicroRNAs miR-US5-1 and miR-UL112-3p Block Proinflammatory Cytokine Production in Response to NF-?B-Activating Factors through Direct Downregulation of IKK? and IKK?
    Authors: MH Hancock, LM Hook, J Mitchell, JA Nelson
    MBio, 2017;8(2):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  3. Interleukin-1 primes human mesenchymal stem cells towards an anti-inflammatory and pro-trophic phenotype in vitro
    Authors: E Redondo-Ca, C Cunningham, J Miller, L Martuscell, S Aoulad-Ali, NJ Rothwell, CM Kielty, SM Allan, E Pinteaux
    Stem Cell Res Ther, 2017;8(1):79.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  4. MC-PPEA as a new and more potent inhibitor of CLP-induced sepsis and pulmonary inflammation than FK866
    Authors: P Huang, MW Lee, K Sadrerafi, DP Heruth, LQ Zhang, D Maulik, SQ Ye
    Drug Des Devel Ther, 2017;11(0):629-641.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  5. Adipogenic differentiation of MSC alters their immunomodulatory properties in a tissue-specific manner
    Authors: H Munir, LS Ward, L Sheriff, S Kemble, S Nayar, F Barone, GB Nash, HM McGettrick
    Stem Cells, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  6. Synovial cell death is regulated by TNF-?-induced expression of B-cell activating factor through an ERK-dependent increase in hypoxia-inducible factor-1?
    Authors: JW Lee, J Lee, SH Um, EY Moon
    Cell Death Dis, 2017;8(4):e2727.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  7. Stepwise inhibition of T cell recruitment at post-capillary venules by orally active desulfated heparins in inflammatory arthritis
    Authors: H Al Faruque, JH Kang, SR Hwang, S Sung, MM Alam, KH Sa, EJ Nam, YR Byun, YM Kang
    PLoS ONE, 2017;12(4):e0176110.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  8. Cell-Specific Variation in E-Selectin Ligand Expression among Human Peripheral Blood Mononuclear Cells: Implications for Immunosurveillance and Pathobiology
    Authors: M Silva, RK Fung, CB Donnelly, PA Videira, R Sackstein
    J. Immunol, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  9. Tim-3 is a Marker of Plasmacytoid Dendritic Cell Dysfunction during HIV Infection and Is Associated with the Recruitment of IRF7 and p85 into Lysosomes and with the Submembrane Displacement of TLR9
    Authors: JA Schwartz, KL Clayton, S Mujib, H Zhang, AK Rahman, J Liu, FY Yue, E Benko, C Kovacs, MA Ostrowski
    J. Immunol, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  10. Cathepsin S is the major activator of the psoriasis-associated proinflammatory cytokine IL-36?
    Authors: JS Ainscough, T Macleod, D McGonagle, R Brakefield, JM Baron, A Alase, M Wittmann, M Stacey
    Proc. Natl. Acad. Sci. U.S.A, 2017;114(13):E2748-E2757.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  11. Interleukin-17A-induced production of acute serum amyloid A by keratinocytes contributes to psoriasis pathogenesis
    Authors: E Couderc, F Morel, P Levillain, A Buffière-M, M Camus, C Paquier, C Bodet, JF Jégou, M Pohin, L Favot, M Garcia, V Huguier, J Mcheik, C Lacombe, H Yssel, G Guillet, FX Bernard, JC Lecron
    PLoS ONE, 2017;12(7):e0181486.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  12. Epigenetically-driven anatomical diversity of synovial fibroblasts guides joint-specific fibroblast functions
    Authors: M Frank-Bert, M Trenkmann, K Klein, E Karouzakis, H Rehrauer, A Bratus, C Kolling, M Armaka, A Filer, BA Michel, RE Gay, CD Buckley, G Kollias, S Gay, C Ospelt
    Nat Commun, 2017;8(0):14852.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  13. Flunarizine suppresses endothelial Angiopoietin-2 in a calcium - dependent fashion in sepsis
    Authors: J Retzlaff, K Thamm, CC Ghosh, W Ziegler, H Haller, SM Parikh, S David
    Sci Rep, 2017;7(0):44113.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  14. A possible role for neutrophils in allergic rhinitis revealed after cellular subclassification
    Authors: J Arebro, S Ekstedt, E Hjalmarsso, O Winqvist, S Kumlien Ge, LO Cardell
    Sci Rep, 2017;7(0):43568.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  15. STAT3/NF-?B-Regulated Lentiviral TK/GCV Suicide Gene Therapy for Cisplatin-Resistant Triple-Negative Breast Cancer
    Authors: WY Kuo, L Hwu, CY Wu, JS Lee, CW Chang, RS Liu
    Theranostics, 2017;7(3):647-663.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  16. A double-negative feedback loop between EpCAM and ERK contributes to the regulation of epithelial-mesenchymal transition in cancer
    Authors: NV Sankpal, TP Fleming, PK Sharma, HJ Wiedner, WE Gillanders
    Oncogene, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  17. HSPA5 Regulates Ferroptotic Cell Death in Cancer Cells
    Authors: S Zhu, Q Zhang, X Sun, HJ Zeh, MT Lotze, R Kang, D Tang
    Cancer Res, 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  18. A Synthetic Mammalian Therapeutic Gene Circuit for Sensing and Suppressing Inflammation
    Authors: A Smole, D Lain??ek, U Bezeljak, S Horvat, R Jerala
    Mol. Ther, 2017;25(1):102-119.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  19. IFN type I and II induce BAFF secretion from human decidual stromal cells
    Authors: AC Lundell, I Nordstr”m, K Andersson, C Lundqvist, E Telemo, S Nava, H Kaipe, A Rudin
    Sci Rep, 2017;7(0):39904.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  20. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
    Authors: KJ Chung, A Chatzigeor, M Economopou, R Garcia-Mar, VI Alexaki, I Mitroulis, M Nati, J Gebler, T Ziemssen, SE Goelz, J Phieler, JH Lim, KP Karalis, T Papayannop, M Blüher, G Hajishenga, T Chavakis
    Nat. Immunol., 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  21. Tissue-resident macrophages can contain replication-competent virus in antiretroviral-naive, SIV-infected Asian macaques
    Authors: SR DiNapoli, AM Ortiz, F Wu, K Matsuda, HL Twigg, VM Hirsch, K Knox, JM Brenchley
    JCI Insight, 2017;2(4):e91214.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Bioassay
  22. Atherosusceptible Shear Stress Activates Endoplasmic Reticulum Stress to Promote Endothelial Inflammation
    Authors: KA Bailey, FG Haj, SI Simon, AG Passerini
    Sci Rep, 2017;7(1):8196.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  23. Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity
    Authors: D Sagar, NP Singh, R Ginwala, X Huang, R Philip, M Nagarkatti, P Nagarkatti, K Neumann, J Ruland, AM Andrews, SH Ramirez, ZK Khan, P Jain
    Sci Rep, 2017;7(1):2707.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  24. Biological and functional characterization of bone marrow-derived mesenchymal stromal cells from patients affected by primary immunodeficiency
    Authors: N Starc, D Ingo, A Conforti, V Rossella, L Tomao, A Pitisci, F De Mattia, I Brigida, M Algeri, M Montanari, G Palumbo, P Merli, P Rossi, A Aiuti, F Locatelli, ME Bernardo
    Sci Rep, 2017;7(1):8153.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  25. Identification of benzazole compounds that induce HIV-1 transcription
    Authors: JD Graci, D Michaels, G Chen, GM Schiralli, S Nodder, M Weetall, GM Karp, Z Gu, JM Colacino, AJ Henderson
    PLoS ONE, 2017;12(6):e0179100.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  26. TNF?-Induced Disruption of the Blood-Retinal Barrier In Vitro Is Regulated by Intracellular 3',5'-Cyclic Adenosine Monophosphate Levels
    Authors: AE van der Wi, IMC Vogels, CJF van Noorde, I Klaassen, RO Schlingema
    Invest. Ophthalmol. Vis. Sci., 2017;58(9):3496-3505.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  27. Frontline Science: c-Myc regulates P-selectin glycoprotein ligand-1 expression in monocytes during HIV-1 infection
    Authors: R Connor, LD Jones, X Qiu, J Thakar, SB Maggirwar
    J. Leukoc. Biol., 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  28. Characterisation of preproendothelin-1 derived peptides identifies Endothelin-Like Domain Peptide as a modulator of Endothelin-1
    Authors: J Yuzugulen, JA Douthwaite, EG Wood, IC Villar, NSA Patel, J Jegard, H Gaertner, I Rossitto-B, K Rose, O Hartley, PR Cutillas, A Ahluwalia, R Corder
    Sci Rep, 2017;7(1):4956.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  29. Proinflammatory Cytokines IL-6 and TNF-? Increased Telomerase Activity through NF-?B/STAT1/STAT3 Activation, and Withaferin A Inhibited the Signaling in Colorectal Cancer Cells
    Authors: SS Chung, Y Wu, Q Okobi, D Adekoya, M Atefi, O Clarke, P Dutta, JV Vadgama
    Mediators Inflamm., 2017;2017(0):5958429.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  30. Transcriptional networks specifying homeostatic and inflammatory programs of gene expression in human aortic endothelial cells
    Authors: NT Hogan, MB Whalen, LK Stolze, NK Hadeli, MT Lam, JR Springstea, CK Glass, CE Romanoski
    Elife, 2017;6(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  31. ADAM10-Interacting Tetraspanins Tspan5 and Tspan17 Regulate VE-Cadherin Expression and Promote T Lymphocyte Transmigration
    Authors: JS Reyat, M Chimen, PJ Noy, J Szyroka, GE Rainger, MG Tomlinson
    J. Immunol., 2017;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  32. Obesity-induces Organ and Tissue Specific Tight Junction Restructuring and Barrier Deregulation by Claudin Switching
    Authors: R Ahmad, B Rah, D Bastola, P Dhawan, AB Singh
    Sci Rep, 2017;7(1):5125.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  33. Upregulation of circulating microRNA-134 in adult-onset Still's disease and its use as potential biomarker
    Authors: TL Liao, YM Chen, CW Hsieh, HH Chen, HC Lee, WT Hung, KT Tang, DY Chen
    Sci Rep, 2017;7(1):4214.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  34. TNF? promotes proliferation of human synovial MSCs while maintaining chondrogenic potential
    Authors: M Shioda, T Muneta, K Tsuji, M Mizuno, K Komori, H Koga, I Sekiya
    PLoS ONE, 2017;12(5):e0177771.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  35. The involvement and possible mechanism of pro-inflammatory tumor necrosis factor alpha (TNF-?) in thoracic ossification of the ligamentum flavum
    Authors: C Zhang, Z Chen, X Meng, M Li, L Zhang, A Huang
    PLoS ONE, 2017;12(6):e0178986.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  36. The autocrine role of proteoglycan-4 (PRG4) in modulating osteoarthritic synoviocyte proliferation and expression of matrix degrading enzymes
    Authors: A Alquraini, M Jamal, L Zhang, T Schmidt, GD Jay, KA Elsaid
    Arthritis Res. Ther., 2017;19(1):89.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  37. Interleukin-20 is triggered by TLR ligands and associates with disease activity in patients with rheumatoid arthritis
    Authors: L Šenolt, K Prajzlerov, H Hulejová, B Šumová, M Filková, D Veigl, K Pavelka, J Vencovský
    Cytokine, 2017;97(0):187-192.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  38. Ziziphus nummularia Inhibits Inflammation-Induced Atherogenic Phenotype of Human Aortic Smooth Muscle Cells
    Authors: M Fardoun, T Al-Shehabi, A El-Yazbi, K Issa, F Zouein, D Maaliki, R Iratni, AH Eid
    Oxid Med Cell Longev, 2017;2017(0):4134093.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  39. A 3D microfluidic model for preclinical evaluation of TCR-engineered T cells against solid tumors
    Authors: A Pavesi, AT Tan, S Koh, A Chia, M Colombo, E Antonecchi, C Miccolis, E Ceccarello, G Adriani, MT Raimondi, RD Kamm, A Bertoletti
    JCI Insight, 2017;2(12):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  40. Identification of a small molecule that primes the type I interferon response to cytosolic DNA
    Authors: S Khiar, M Lucas-Hour, S Nisole, N Smith, O Helynck, M Bourgine, C Ruffié, JP Herbeuval, H Munier-Leh, F Tangy, PO Vidalain
    Sci Rep, 2017;7(1):2561.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  41. Differentiation of Inflammation-Responsive Astrocytes from Glial Progenitors Generated from Human Induced Pluripotent Stem Cells
    Authors: R Santos, KC Vadodaria, BN Jaeger, A Mei, S Lefcochilo, APD Mendes, G Erikson, M Shokhirev, L Randolph-M, C Fredlender, S Dave, R Oefner, C Fitzpatric, M Pena, JJ Barron, M Ku, AM Denli, BE Kerman, P Charnay, JR Kelsoe, MC Marchetto, FH Gage
    Stem Cell Reports, 2017;8(6):1757-1769.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  42. Mosquito Saliva Increases Endothelial Permeability in the Skin, Immune Cell Migration, and Dengue Pathogenesis during Antibody-Dependent Enhancement
    Authors: Michael A Schmid
    PLoS Pathog, 2016;12(6):e1005676.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  43. Endothelial Cell Activation is Regulated by Epidermal Growth Factor-Like Domain 7 (Egfl7) during Inflammation
    J Biol Chem, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  44. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    Cell, 2016;0(0):.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  45. IRAK1, a Target of miR-146b, Reduces Cell Aggressiveness of Human Papillary Thyroid Carcinoma
    J Clin Endocrinol Metab, 2016;0(0):jc20162276.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  46. Directed elimination of senescent cells by inhibition of BCL-W and BCL-XL
    Authors: R Yosef, N Pilpel, R Tokarsky-A, A Biran, Y Ovadya, S Cohen, E Vadai, L Dassa, E Shahar, R Condiotti, I Ben-Porath, V Krizhanovs
    Nat Commun, 2016;7(0):11190.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  47. Androgen-Sensitized Apoptosis of HPr-1AR Human Prostate Epithelial Cells
    PLoS ONE, 2016;11(5):e0156145.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  48. Mycobacterium massiliense Induces Macrophage Extracellular Traps with Facilitating Bacterial Growth
    PLoS ONE, 2016;11(5):e0155685.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  49. Human lung fibroblasts may modulate dendritic cell phenotype and function: results from a pilot in vitro study
    Authors: O Freynet, J Marchal-So, F Jean-Louis, A Mailleux, B Crestani, P Soler, L Michel
    Respir Res, 2016;17(1):36.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  50. Interferon-? and Tumor Necrosis Factor-? Polarize Bone Marrow Stromal Cells Uniformly to a Th1 Phenotype
    Sci Rep, 2016;6(0):26345.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  51. IL-3 Decreases Cartilage Degeneration by Downregulating Matrix Metalloproteinases and Reduces Joint Destruction in Osteoarthritic Mice
    J Immunol, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  52. Mitochondrial Protein PGAM5 Regulates Mitophagic Protection against Cell Necroptosis.
    Authors: Lu W, Sun J, Yoon J, Zhang Y, Zheng L, Murphy E, Mattson M, Lenardo M
    PLoS ONE, 2016;11(1):e0147792.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  53. Tissue engineering of acellular vascular grafts capable of somatic growth in young lambs
    Nat Commun, 2016;7(0):12951.
    Species: Ovine
    Sample Type: Whole Tissue
    Application: Bioassay
  54. A Common Genetic Variant in TLR1 Enhances Human Neutrophil Priming and Impacts Length of Intensive Care Stay in Pediatric Sepsis.
    Authors: Whitmore L, Hook J, Philiph A, Hilkin B, Bing X, Ahn C, Wong H, Ferguson P, Moreland J
    J Immunol, 2016;196(3):1376-86.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  55. Retinal pigment epithelial cell expression of active Rap 1a by scAAV2 inhibits choroidal neovascularization
    Mol Ther Methods Clin Dev, 2016;3(0):16056.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  56. Up-Regulation of Human Inducible Nitric Oxide Synthase by p300 Transcriptional Complex.
    Authors: Guo Z, Zheng L, Liao X, Geller D
    PLoS ONE, 2016;11(1):e0146640.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  57. Growth Differentiation Factor-15-Induced Contractile Activity and Extracellular Matrix Production in Human Trabecular Meshwork Cells
    Invest. Ophthalmol. Vis. Sci, 2016;57(15):6482-6495.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  58. IL-37 suppresses hepatocellular carcinoma growth by converting pSmad3 signaling from JNK/pSmad3L/c-Myc oncogenic signaling to pSmad3C/P21 tumor-suppressive signaling
    Authors: R Liu, C Tang, A Shen, H Luo, X Wei, D Zheng, C Sun, Z Li, D Zhu, T Li, Z Wu
    Oncotarget, 2016;7(51):85079-85096.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  59. Serum YKL-40 as a marker of liver fibrosis in patients with non-alcoholic fatty liver disease
    Sci Rep, 2016;6(0):35282.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  60. Dual inhibition of CDK4/Rb and PI3K/AKT/mTOR pathways by ON123300 induces synthetic lethality in mantle cell lymphomas.
    Authors: Divakar S, Ramana Reddy M, Cosenza S, Baker S, Perumal D, Antonelli A, Brody J, Akula B, Parekh S, Premkumar Reddy E
    Leukemia, 2016;30(1):86-93.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  61. Genetic, immunological, and clinical features of patients with bacterial and fungal infections due to inherited IL-17RA deficiency
    Proc. Natl. Acad. Sci. U.S.A, 2016;0(0):.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  62. Tubular epithelial cells in renal clear cell carcinoma express high RIPK1/3 and show increased susceptibility to TNF receptor 1-induced necroptosis
    Cell Death Dis, 2016;7(6):e2287.
    Species: Human
    Sample Type: Whole Tissue
    Application: Bioassay
  63. Macrophages Enhance Migration in Inflammatory Breast Cancer Cells via RhoC GTPase Signaling
    Sci Rep, 2016;6(0):39190.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  64. Prenylated Polyphenols from Clusiaceae and Calophyllaceae with Immunomodulatory Activity on Endothelial Cells
    PLoS ONE, 2016;11(12):e0167361.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  65. P311 induces the transdifferentiation of epidermal stem cells to myofibroblast-like cells by stimulating transforming growth factor ?1 expression
    Stem Cell Res Ther, 2016;7(1):175.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  66. Impaired Tight Junctions in Atopic Dermatitis Skin and in a Skin-Equivalent Model Treated with Interleukin-17
    PLoS ONE, 2016;11(9):e0161759.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  67. Facile supermolecular aptamer inhibitors of L-selectin.
    Authors: Chang, Elizabet, Eckert, Mark A, Ali, M Monsur, Riazifar, Hamidrez, Pone, Egest J, Liu, Linan, Zhao, Weian
    PLoS ONE, 2015;10(3):e0123034.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  68. RelB/p50 complexes regulate cytokine-induced YKL-40 expression.
    Authors: Bhardwaj R, Yester J, Singh S, Biswas D, Surace M, Waters M, Hauser K, Yao Z, Boyce B, Kordula T
    J Immunol, 2015;194(6):2862-70.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  69. Cancer-testis antigen SLLP1 represents a promising target for the immunotherapy of multiple myeloma.
    Authors: Yousef S, Heise J, Lajmi N, Bartels K, Kroger N, Luetkens T, Atanackovic D
    J Transl Med, 2015;13(0):197.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  70. The cerebral cavernous malformation 3 gene is necessary for senescence induction.
    Authors: Guerrero A, Iglesias C, Raguz S, Floridia E, Gil J, Pombo C, Zalvide J
    Aging Cell, 2015;14(2):274-83.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  71. Th17-type cytokines, IL-6 and TNF-alpha synergistically activate STAT3 and NF-kB to promote colorectal cancer cell growth.
    Authors: De Simone V, Franze E, Ronchetti G, Colantoni A, Fantini M, Di Fusco D, Sica G, Sileri P, MacDonald T, Pallone F, Monteleone G, Stolfi C
    Oncogene, 2015;34(27):3493-503.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  72. Human HOIP and LUBAC deficiency underlies autoinflammation, immunodeficiency, amylopectinosis, and lymphangiectasia.
    Authors: Boisson B, Laplantine E, Dobbs K, Cobat A, Tarantino N, Hazen M, Lidov H, Hopkins G, DU L, Belkadi A, Chrabieh M, Itan Y, Picard C, Fournet J, Eibel H, Tsitsikov E, Pai S, Abel L, Al-Herz W, Casanova J, Israel A, Notarangelo L
    J Exp Med, 2015;212(6):939-51.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  73. Interleukin-22 is increased in multiple sclerosis patients and targets astrocytes.
    Authors: Perriard G, Mathias A, Enz L, Canales M, Schluep M, Gentner M, Schaeren-Wiemers N, Du Pasquier R
    J Neuroinflammation, 2015;12(0):119.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  74. BET bromodomain inhibition suppresses transcriptional responses to cytokine-Jak-STAT signaling in a gene-specific manner in human monocytes.
    Authors: Chan C, Fang C, Qiao Y, Yarilina A, Prinjha R, Ivashkiv L
    Eur J Immunol, 2015;45(1):287-97.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  75. 6-Mercaptopurine reduces cytokine and Muc5ac expression involving inhibition of NFkappaB activation in airway epithelial cells.
    Authors: Kurakula K, Hamers A, van Loenen P, de Vries C
    Respir Res, 2015;16(0):73.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  76. Inflammation and hypoxia linked to renal injury by CCAAT/enhancer-binding protein delta.
    Authors: Yamaguchi J, Tanaka T, Eto N, Nangaku M
    Kidney Int, 2015;88(2):262-75.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  77. Inhibition of T-cell activation by retinal pigment epithelial cells derived from induced pluripotent stem cells.
    Authors: Sugita S, Kamao H, Iwasaki Y, Okamoto S, Hashiguchi T, Iseki K, Hayashi N, Mandai M, Takahashi M
    Invest Ophthalmol Vis Sci, 2015;56(2):1051-62.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  78. Persistence and toxin production by Clostridium difficile within human intestinal organoids result in disruption of epithelial paracellular barrier function.
    Authors: Leslie J, Huang S, Opp J, Nagy M, Kobayashi M, Young V, Spence J
    Infect Immun, 2015;83(1):138-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  79. Broadly-specific cytotoxic T cells targeting multiple HIV antigens are expanded from HIV+ patients: implications for immunotherapy.
    Authors: Lam, Sharon, Sung, Julia, Cruz, Conrad, Castillo-Caro, Paul, Ngo, Minhtran, Garrido, Carolina, Kuruc, Joann, Archin, Nancie, Rooney, Cliona, Margolis, David, Bollard, Catherin
    Mol Ther, 2015;23(2):387-95.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  80. Nuclear FAM21 participates in NF-kappaB-dependent gene regulation in pancreatic cancer cells.
    Authors: Deng Z, Gomez T, Osborne D, Phillips-Krawczak C, Zhang J, Billadeau D
    J Cell Sci, 2015;128(2):373-84.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  81. L-selectin shedding is activated specifically within transmigrating pseudopods of monocytes to regulate cell polarity in vitro.
    Authors: Rzeniewicz K, Newe A, Rey Gallardo A, Davies J, Holt M, Patel A, Charras G, Stramer B, Molenaar C, Tedder T, Parsons M, Ivetic A
    Proc Natl Acad Sci U S A, 2015;112(12):E1461-70.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  82. The effect of protease inhibitors on the induction of osteoarthritis-related biomarkers in bovine full-depth cartilage explants.
    Authors: He Y, Zheng Q, Jiang M, Sun S, Christiansen T, Kassem M, Karsdal M, Bay-Jensen A
    PLoS ONE, 2015;10(0):.
    Species: Bovine
    Sample Type: Whole Tissue
    Application: Bioassay
  83. Molecular mechanisms linking high dose medroxyprogesterone with HIV-1 risk.
    Authors: Irvin S, Herold B
    PLoS ONE, 2015;10(3):e0121135.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  84. Cytokine-induced loss of glucocorticoid function: effect of kinase inhibitors, long-acting beta(2)-adrenoceptor [corrected] agonist and glucocorticoid receptor ligands.
    Authors: Rider C, Shah S, Miller-Larsson A, Giembycz M, Newton R
    PLoS ONE, 2015;10(1):e0116773.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  85. Cytosolic phospholipase A2 modulates TLR2 signaling in synoviocytes.
    Authors: Sommerfelt R, Feuerherm A, Skuland T, Johansen B
    PLoS ONE, 2015;10(4):e0119088.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  86. Detection and quantification of microparticles from different cellular lineages using flow cytometry. Evaluation of the impact of secreted phospholipase A2 on microparticle assessment.
    Authors: Rousseau M, Belleannee C, Duchez A, Cloutier N, Levesque T, Jacques F, Perron J, Nigrovic P, Dieude M, Hebert M, Gelb M, Boilard E
    PLoS ONE, 2015;10(1):e0116812.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  87. Ubiquitin-associated domain-containing ubiquitin regulatory X (UBX) protein UBXN1 is a negative regulator of nuclear factor kappaB (NF-kappaB) signaling.
    Authors: Wang Y, Tan B, Mu R, Chang Y, Wu M, Tu H, Zhang Y, Guo S, Qin X, Li T, Li W, Li A, Zhang X, Li H
    J Biol Chem, 2015;290(16):10395-405.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  88. Role of transforming growth factor-activated kinase-1 on tumor necrosis factor-alpha actions in human adipose tissue-derived stromal cells.
    Authors: Lee S, Lee J, Shin K, Kim D, Kim Y, Bae Y, Jung J
    Stem Cells Dev, 2015;24(7):836-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  89. IL-4 Downregulates IL-1beta and IL-6 and Induces GATA3 in Psoriatic Epidermal Cells: Route of Action of a Th2 Cytokine.
    Authors: Onderdijk A, Baerveldt E, Kurek D, Kant M, Florencia E, Debets R, Prens E
    J Immunol, 2015;195(4):1744-52.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  90. PHLDA1 expression is controlled by an estrogen receptor-NFkappaB-miR-181 regulatory loop and is essential for formation of ER+ mammospheres.
    Authors: Kastrati I, Canestrari E, Frasor J
    Oncogene, 2015;34(18):2309-16.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  91. Tumour necrosis factor receptor I blockade shows that TNF-dependent and TNF-independent mechanisms synergise in TNF receptor associated periodic syndrome.
    Authors: Fairclough L, Stoop A, Negm O, Radford P, Tighe P, Todd I
    Eur J Immunol, 2015;45(10):2937-44.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  92. Tissue Inhibitor of Metalloproteinase-4 Triggers Apoptosis in Cervical Cancer Cells.
    Authors: Lizarraga F, Ceballos-Cancino G, Espinosa M, Vazquez-Santillan K, Maldonado V, Melendez-Zajgla J
    PLoS ONE, 2015;10(8):e0135929.
  93. CYLD and the NEMO Zinc Finger Regulate Tumor Necrosis Factor Signaling and Early Embryogenesis.
    Authors: Zhao Y, Ma C, Wu L, Iwai K, Ashwell J, Oltz E, Ballard D, Jain A
    J Biol Chem, 2015;290(36):22076-84.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  94. Endothelial CD99 signals through soluble adenylyl cyclase and PKA to regulate leukocyte transendothelial migration.
    Authors: Watson R, Buck J, Levin L, Winger R, Wang J, Arase H, Muller W
    J Exp Med, 2015;212(7):1021-41.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  95. RIP1 Kinase Is an Oncogenic Driver in Melanoma.
    Authors: Liu X, Lai F, Yan X, Jiang C, Guo S, Wang C, Croft A, Tseng H, Wilmott J, Scolyer R, Jin L, Zhang X
    Cancer Res, 2015;75(8):1736-48.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  96. Oncogenic Transformation Can Orchestrate Immune Evasion and Inflammation in Human Mesenchymal Stem Cells Independently of Extrinsic Immune-Selective Pressure.
    Authors: Miranda A, Funes J, Sanchez N, Limia C, Mesa M, Quezada S, Perez R, de Leon J
    Cancer Res, 2015;75(15):3032-42.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  97. Boswellia serrata Preserves Intestinal Epithelial Barrier from Oxidative and Inflammatory Damage.
    Authors: Catanzaro D, Rancan S, Orso G, Dall'Acqua S, Brun P, Giron M, Carrara M, Castagliuolo I, Ragazzi E, Caparrotta L, Montopoli M
    PLoS ONE, 2015;10(5):e0125375.
  98. Anti-apoptotic NF-kappaB and "gain of function" mutp53 in concert act pro-apoptotic in response to UVB+IL-1 via enhanced TNF production.
    Authors: Muller I, Beissert S, Kulms D
    J Invest Dermatol, 2015;135(3):851-60.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  99. Characterization of platelet-monocyte complexes in HIV-1-infected individuals: possible role in HIV-associated neuroinflammation.
    Authors: Singh, Meera V, Davidson, Donna C, Jackson, Joseph W, Singh, Vir B, Silva, Jharon, Ramirez, Servio H, Maggirwar, Sanjay B
    J Immunol, 2014;192(10):4674-84.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  100. Kinase control of latent HIV-1 infection: PIM-1 kinase as a major contributor to HIV-1 reactivation.
    Authors: Duverger, Alexandr, Wolschendorf, Frank, Anderson, Joshua C, Wagner, Frederic, Bosque, Alberto, Shishido, Takao, Jones, Jennifer, Planelles, Vicente, Willey, Christop, Cron, Randall, Kutsch, Olaf
    J Virol, 2014;88(1):364-76.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  101. Overexpression of CCN3 inhibits inflammation and progression of atherosclerosis in apolipoprotein E-deficient mice.
    Authors: Liu J, Ren Y, Kang L, Zhang L
    PLoS ONE, 2014;9(4):e94912.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  102. Innate lymphoid cells integrate stromal and immunological signals to enhance antibody production by splenic marginal zone B cells.
    Authors: Magri G, Miyajima M, Bascones S, Mortha A, Puga I, Cassis L, Barra C, Comerma L, Chudnovskiy A, Gentile M, Llige D, Cols M, Serrano S, Arostegui J, Juan M, Yague J, Merad M, Fagarasan S, Cerutti A
    Nat Immunol, 2014;15(4):354-64.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  103. Membrane type 1-matrix metalloproteinase/Akt signaling axis modulates TNF-alpha-induced procoagulant activity and apoptosis in endothelial cells.
    Authors: Ohkawara H, Ishibashi T, Sugimoto K, Ikeda K, Ogawa K, Takeishi Y
    PLoS ONE, 2014;9(8):e105697.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  104. Absence of a role for interleukin-13 in inflammatory bowel disease.
    Authors: Biancheri P, Di Sabatino A, Ammoscato F, Facciotti F, Caprioli F, Curciarello R, Hoque S, Ghanbari A, Joe-Njoku I, Giuffrida P, Rovedatti L, Geginat J, Corazza G, MacDonald T
    Eur J Immunol, 2014;44(2):370-85.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  105. Influence of proinflammatory stimuli on the expression of vascular ribonuclease 1 in endothelial cells.
    Authors: Gansler J, Preissner K, Fischer S
    FASEB J, 2014;28(2):752-60.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  106. Thymic stromal lymphopoietin links keratinocytes and dendritic cell-derived IL-23 in patients with psoriasis.
    Authors: Volpe E, Pattarini L, Martinez-Cingolani C, Meller S, Donnadieu M, Bogiatzi S, Fernandez M, Touzot M, Bichet J, Reyal F, Paronetto M, Chiricozzi A, Chimenti S, Nasorri F, Cavani A, Kislat A, Homey B, Soumelis V
    J Allergy Clin Immunol, 2014;134(2):373-81.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  107. Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1beta, TNF-alpha, and IFN-gamma.
    Authors: Sidney L, Kirkham G, Buttery L
    Stem Cells Dev, 2014;23(6):605-17.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  108. Toxoplasma gondii virulence factor ROP18 inhibits the host NF-kappaB pathway by promoting p65 degradation.
    Authors: Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J
    J Biol Chem, 2014;289(18):12578-92.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  109. Novel ex vivo culture method for human monocytes uses shear flow to prevent total loss of transendothelial diapedesis function.
    Authors: Tsubota Y, Frey J, Raines E
    J Leukoc Biol, 2014;95(1):191-5.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  110. Transcriptional repression of the transforming growth factor beta (TGF-beta) Pseudoreceptor BMP and activin membrane-bound inhibitor (BAMBI) by Nuclear Factor kappaB (NF-kappaB) p50 enhances TGF-beta signaling in hepatic stellate cells.
    Authors: Liu C, Chen X, Yang L, Kisseleva T, Brenner D, Seki E
    J Biol Chem, 2014;289(10):7082-91.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  111. Oncostatin M mediates STAT3-dependent intestinal epithelial restitution via increased cell proliferation, decreased apoptosis and upregulation of SERPIN family members.
    Authors: Beigel F, Friedrich M, Probst C, Sotlar K, Goke B, Diegelmann J, Brand S
    PLoS ONE, 2014;9(4):e93498.
    Species: N/A
    Sample Type: N/A
    Application: WB Standard
  112. Oncogenic Ras induces inflammatory cytokine production by upregulating the squamous cell carcinoma antigens SerpinB3/B4.
    Authors: Catanzaro J, Sheshadri N, Pan J, Sun Y, Shi C, Li J, Powers R, Crawford H, Zong W
    Nat Commun, 2014;5(0):3729.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  113. CD24-triggered caspase-dependent apoptosis via mitochondrial membrane depolarization and reactive oxygen species production of human neutrophils is impaired in sepsis.
    Authors: Parlato M, Souza-Fonseca-Guimaraes F, Philippart F, Misset B, Adib-Conquy M, Cavaillon J
    J Immunol, 2014;192(5):2449-59.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  114. A novel CD44-binding peptide from the pro-matrix metalloproteinase-9 hemopexin domain impairs adhesion and migration of chronic lymphocytic leukemia (CLL) cells.
    Authors: Ugarte-Berzal E, Bailon E, Amigo-Jimenez I, Albar J, Garcia-Marco J, Garcia-Pardo A
    J Biol Chem, 2014;289(22):15340-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  115. Family with sequence similarity 5, member C (FAM5C) increases leukocyte adhesion molecules in vascular endothelial cells: implication in vascular inflammation.
    Authors: Sato J, Kinugasa M, Satomi-Kobayashi S, Hatakeyama K, Knox A, Asada Y, Wierman M, Hirata K, Rikitake Y
    PLoS ONE, 2014;9(9):e107236.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  116. Tumour necrosis factor-alpha regulates human eosinophil apoptosis via ligation of TNF-receptor 1 and balance between NF-kappaB and AP-1.
    Authors: Kankaanranta H, Ilmarinen P, Zhang X, Adcock I, Lahti A, Barnes P, Giembycz M, Lindsay M, Moilanen E
    PLoS ONE, 2014;9(2):e90298.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  117. IL-2 phosphorylates STAT5 to drive IFN-gamma production and activation of human dendritic cells.
    Authors: Herr F, Lemoine R, Gouilleux F, Meley D, Kazma I, Heraud A, Velge-Roussel F, Baron C, Lebranchu Y
    J Immunol, 2014;192(12):5660-70.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  118. High activities of BACE1 in brains with mild cognitive impairment.
    Authors: Cheng X, He P, Lee T, Yao H, Li R, Shen Y
    Am J Pathol, 2014;184(1):141-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  119. Pharmacologic IKK/NF-kappaB inhibition causes antigen presenting cells to undergo TNFalpha dependent ROS-mediated programmed cell death.
    Authors: Tilstra J, Gaddy D, Zhao J, Dave S, Niedernhofer L, Plevy S, Robbins P
    Sci Rep, 2014;4(0):3631.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  120. Distinct mechanisms of induction of hepatic growth hormone resistance by endogenous IL-6, TNF-alpha, and IL-1beta.
    Authors: Zhao Y, Xiao X, Frank S, Lin H, Xia Y
    Am J Physiol Endocrinol Metab, 2014;307(2):E186-98.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  121. Stiffness-activated GEF-H1 expression exacerbates LPS-induced lung inflammation.
    Authors: Mambetsariev I, Tian Y, Wu T, Lavoie T, Solway J, Birukov K, Birukova A
    PLoS ONE, 2014;9(4):e92670.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  122. Microparticle alpha-2-macroglobulin enhances pro-resolving responses and promotes survival in sepsis.
    Authors: Dalli, Jesmond, Norling, Lucy V, Montero-Melendez, Trinidad, Federici Canova, Donata, Lashin, Hazem, Pavlov, Anton M, Sukhorukov, Gleb B, Hinds, Charles, Perretti, Mauro
    EMBO Mol Med, 2014;6(1):27-42.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  123. Sphingosine 1-phosphate induces neutrophil chemoattractant IL-8: repression by steroids.
    Authors: Rahman M, Alkhouri H, Tang F, Che W, Ge Q, Ammit A
    PLoS ONE, 2014;9(3):e92466.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  124. Endothelial activation by platelets from sickle cell anemia patients.
    Authors: Proenca-Ferreira R, Brugnerotto A, Garrido V, Dominical V, Vital D, Ribeiro M, dos Santos M, Traina F, Olalla-Saad S, Costa F, Conran N
    PLoS ONE, 2014;9(2):e89012.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  125. Identification of novel epitopes from human papillomavirus type 18 E7 that can sensitize PBMCs of multiple HLA class I against human cervical cancer.
    Authors: Kim S, Chung H, Lee K, Lim J
    J Transl Med, 2014;12(0):229.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  126. Carbamoylating activity associated with the activation of the antitumor agent laromustine inhibits angiogenesis by inducing ASK1-dependent endothelial cell death.
    Authors: Ji, Weidong, Yang, Mei, Praggastis, Alexandr, Li, Yonghao, Zhou, Huanjiao, He, Yun, Ghazvinian, Roxanne, Cincotta, Dylan J, Rice, Kevin P, Min, Wang
    PLoS ONE, 2014;9(7):e103224.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  127. Rad GTPase inhibits the NFkappaB pathway through interacting with RelA/p65 to impede its DNA binding and target gene transactivation.
    Authors: Hsiao B, Chang T, Wu I, Chen M
    Cell Signal, 2014;26(7):1437-44.
  128. Apremilast is a selective PDE4 inhibitor with regulatory effects on innate immunity.
    Authors: Schafer P, Parton A, Capone L, Cedzik D, Brady H, Evans J, Man H, Muller G, Stirling D, Chopra R
    Cell Signal, 2014;26(9):2016-29.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  129. Caffeic acid derivatives inhibit the growth of colon cancer: involvement of the PI3-K/Akt and AMPK signaling pathways.
    Authors: Chiang, En-Pei I, Tsai, Shu-Yao, Kuo, Yueh-Hsi, Pai, Man-Hui, Chiu, Hsi-Lin, Rodriguez, Raymond, Tang, Feng-Yao
    PLoS ONE, 2014;9(6):e99631.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  130. Restoring Akt1 activity in outgrowth endothelial cells from South Asian men rescues vascular reparative potential.
    Authors: Cubbon R, Yuldasheva N, Viswambharan H, Mercer B, Baliga V, Stephen S, Askham J, Sukumar P, Skromna A, Mughal R, Walker A, Bruns A, Bailey M, Galloway S, Imrie H, Gage M, Rakobowchuk M, Li J, Porter K, Ponnambalam S, Wheatcroft S, Beech D, Kearney M
    Stem Cells, 2014;32(10):2714-23.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  131. Neutrophils from vasculitis patients exhibit an increased propensity for activation by anti-neutrophil cytoplasmic antibodies.
    Authors: Ohlsson S, Ohlsson S, Soderberg D, Gunnarsson L, Pettersson A, Segelmark M, Hellmark T
    Clin Exp Immunol, 2014;176(3):363-72.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  132. TRAIL/DR5 signaling promotes macrophage foam cell formation by modulating scavenger receptor expression.
    Authors: Liu F, Wu X, Zhang Y, Wang Y, Jiang F
    PLoS ONE, 2014;9(1):e87059.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  133. TRIM38 inhibits TNFalpha- and IL-1beta-triggered NF-kappaB activation by mediating lysosome-dependent degradation of TAB2/3.
    Authors: Hu M, Yang Q, Zhang J, Liu S, Zhang Y, Lin H, Huang Z, Wang Y, Zhang X, Zhong B, Shu H
    Proc Natl Acad Sci U S A, 2014;111(4):1509-14.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  134. A20 deficiency causes spontaneous neuroinflammation in mice.
    Authors: Guedes R, Csizmadia E, Moll H, Ma A, Ferran C, da Silva C
    J Neuroinflammation, 2014;11(0):122.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Stimulation
  135. Selective and potent Akt inhibition triggers anti-myeloma activities and enhances fatal endoplasmic reticulum stress induced by proteasome inhibition.
    Authors: Mimura N, Hideshima T, Shimomura T, Suzuki R, Ohguchi H, Rizq O, Kikuchi S, Yoshida Y, Cottini F, Jakubikova J, Cirstea D, Gorgun G, Minami J, Tai Y, Richardson P, Utsugi T, Iwama A, Anderson K
    Cancer Res, 2014;74(16):4458-69.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  136. The differential regulation of human ACT1 isoforms by Hsp90 in IL-17 signaling.
    Authors: Wu L, Wang C, Boisson B, Misra S, Rayman P, Finke J, Puel A, Casanova J, Li X
    J Immunol, 2014;193(4):1590-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  137. The RhoA guanine nucleotide exchange factor, LARG, mediates ICAM-1-dependent mechanotransduction in endothelial cells to stimulate transendothelial migration.
    Authors: Lessey-Morillon E, Osborne L, Monaghan-Benson E, Guilluy C, O'Brien E, Superfine R, Burridge K
    J Immunol, 2014;192(7):3390-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  138. Nanoparticle-mediated combinatorial targeting of multiple human dendritic cell (DC) subsets leads to enhanced T cell activation via IL-15-dependent DC crosstalk.
    Authors: Sehgal K, Ragheb R, Fahmy T, Dhodapkar M, Dhodapkar K
    J Immunol, 2014;193(5):2297-305.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  139. Vaspin inhibits cytokine-induced nuclear factor-kappa B activation and adhesion molecule expression via AMP-activated protein kinase activation in vascular endothelial cells.
    Authors: Jung C, Lee M, Kang Y, Lee Y, Yoon H, Kang S, Lee W, Park J
    Cardiovasc Diabetol, 2014;13(0):41.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  140. Suberoylanilide hydroxamic acid-induced HeLa cell death is closely correlated with oxidative stress and thioredoxin 1 levels.
    Authors: You B, Park W
    Int J Oncol, 2014;44(5):1745-55.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  141. Morin, a flavonoid from Moraceae, suppresses growth and invasion of the highly metastatic breast cancer cell line MDA-MB231 partly through suppression of the Akt pathway.
    Authors: Jin H, Lee W, Eun S, Jung J, Park H, Kim G, Choi Y, Ryu C, Jung J, Hong S, Shin S, Kim H
    Int J Oncol, 2014;45(4):1629-37.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  142. Extrinsic apoptosis is impeded by direct binding of the APL fusion protein NPM-RAR to TRADD.
    Authors: Chattopadhyay A, Hood B, Conrads T, Redner R
    Mol Cancer Res, 2014;12(9):1283-91.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  143. Enriched protein screening of human bone marrow mesenchymal stromal cell secretions reveals MFAP5 and PENK as novel IL-10 modulators.
    Authors: Milwid, Jack M, Elman, Jessica, Li, Matthew, Shen, Keyue, Manrai, Arjun, Gabow, Aaron, Yarmush, Joshua, Jiao, Yunxin, Fletcher, Anne, Lee, Jungwoo, Cima, Michael, Yarmush, Martin L, Parekkadan, Biju
    Mol Ther, 2014;22(5):999-1007.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  144. Cell density impacts epigenetic regulation of cytokine-induced E-selectin gene expression in vascular endothelium.
    Authors: Hamada K, Osaka M, Yoshida M
    PLoS ONE, 2014;9(4):e90502.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  145. MicroRNA-26b suppresses the NF-kappaB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3.
    Authors: Zhao N, Wang R, Zhou L, Zhu Y, Gong J, Zhuang S
    Mol Cancer, 2014;13(0):35.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  146. p38-Mediated phosphorylation of Eps15 endocytic adaptor protein.
    Authors: Zhou Y, Tanaka T, Sugiyama N, Yokoyama S, Kawasaki Y, Sakuma T, Ishihama Y, Saiki I, Sakurai H
    FEBS Lett, 2014;588(1):131-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  147. Osteodifferentiated mesenchymal stem cells from bone marrow and adipose tissue express HLA-G and display immunomodulatory properties in HLA-mismatched settings: implications in bone repair therapy.
    Authors: Montespan F, Deschaseaux F, Sensebe L, Carosella E, Rouas-Freiss N
    J Immunol Res, 2014;2014(0):230346.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  148. Cytokines alter IgA1 O-glycosylation by dysregulating C1GalT1 and ST6GalNAc-II enzymes.
    Authors: Suzuki, Hitoshi, Raska, Milan, Yamada, Koshi, Moldoveanu, Zina, Julian, Bruce A, Wyatt, Robert J, Tomino, Yasuhiko, Gharavi, Ali G, Novak, Jan
    J Biol Chem, 2014;289(8):5330-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  149. Interleukin 7 plays a role in T lymphocyte apoptosis inhibition driven by mesenchymal stem cell without favoring proliferation and cytokines secretion.
    Authors: Normanton M, Alvarenga H, Hamerschlak N, Ribeiro A, Kondo A, Rizzo L, Marti L
    PLoS ONE, 2014;9(9):e106673.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  150. TNF-alpha induces matrix metalloproteinase-9-dependent soluble intercellular adhesion molecule-1 release via TRAF2-mediated MAPKs and NF-kappaB activation in osteoblast-like MC3T3-E1 cells.
    Authors: Tsai C, Chen W, Hsieh H, Chi P, Hsiao L, Yang C
    J Biomed Sci, 2014;21(0):12.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  151. Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M.
    Authors: Rabeony H, Petit-Paris I, Garnier J, Barrault C, Pedretti N, Guilloteau K, Jegou J, Guillet G, Huguier V, Lecron J, Bernard F, Morel F
    PLoS ONE, 2014;9(7):e101937.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  152. TNF-alpha blockade induces IL-10 expression in human CD4+ T cells.
    Authors: Evans H, Roostalu U, Walter G, Gullick N, Frederiksen K, Roberts C, Sumner J, Baeten D, Gerwien J, Cope A, Geissmann F, Kirkham B, Taams L
    Nat Commun, 2014;5(0):3199.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  153. Adoptive immunotherapy with MUC1-mRNA transfected dendritic cells and cytotoxic lymphocytes plus gemcitabine for unresectable pancreatic cancer.
    Authors: Shindo Y, Hazama S, Maeda Y, Matsui H, Iida M, Suzuki N, Yoshimura K, Ueno T, Yoshino S, Sakai K, Suehiro Y, Yamasaki T, Hinoda Y, Oka M
    J Transl Med, 2014;12(0):175.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  154. DeltaNp63 controls a TLR3-mediated mechanism that abundantly provides thymic stromal lymphopoietin in atopic dermatitis.
    Authors: Kubo T, Kamekura R, Kumagai A, Kawata K, Yamashita K, Mitsuhashi Y, Kojima T, Sugimoto K, Yoneta A, Sumikawa Y, Yamashita T, Sato N, Himi T, Ichimiya S
    PLoS ONE, 2014;9(8):e105498.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  155. Miro-1 links mitochondria and microtubule Dynein motors to control lymphocyte migration and polarity.
    Authors: Morlino G, Barreiro O, Baixauli F, Robles-Valero J, Gonzalez-Granado J, Villa-Bellosta R, Cuenca J, Sanchez-Sorzano C, Veiga E, Martin-Cofreces N, Sanchez-Madrid F
    Mol Cell Biol, 2014;34(8):1412-26.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  156. Linkage of inflammation and oxidative stress via release of glutathionylated peroxiredoxin-2, which acts as a danger signal.
    Authors: Salzano S, Checconi P, Hanschmann E, Lillig C, Bowler L, Chan P, Vaudry D, Mengozzi M, Coppo L, Sacre S, Atkuri K, Sahaf B, Herzenberg L, Herzenberg L, Mullen L, Ghezzi P
    Proc Natl Acad Sci U S A, 2014;111(33):12157-62.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  157. A pro-inflammatory signalome is constitutively activated by C33Y mutant TNF receptor 1 in TNF receptor-associated periodic syndrome (TRAPS).
    Authors: Negm O, Mannsperger H, McDermott E, Drewe E, Powell R, Todd I, Fairclough L, Tighe P
    Eur J Immunol, 2014;44(7):2096-110.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  158. p300-mediated acetylation of COMMD1 regulates its stability, and the ubiquitylation and nucleolar translocation of the RelA NF-kappaB subunit.
    Authors: O'Hara A, Simpson J, Morin P, Loveridge C, Williams A, Novo S, Stark L
    J Cell Sci, 2014;127(0):3659-65.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  159. Miro1 regulates intercellular mitochondrial transport & enhances mesenchymal stem cell rescue efficacy.
    Authors: Ahmad T, Mukherjee S, Pattnaik B, Kumar M, Singh S, Kumar M, Rehman R, Tiwari B, Jha K, Barhanpurkar A, Wani M, Roy S, Mabalirajan U, Ghosh B, Agrawal A
    EMBO J, 2014;33(9):994-1010.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  160. Durable remission of renal cell carcinoma in conjuncture with graft versus host disease following allogeneic stem cell transplantation and donor lymphocyte infusion: rule or exception?
    Authors: van Bergen, Cornelis, Verdegaal, Elisabet, Honders, M Wilhel, Hoogstraten, Conny, Steijn-van Tol, A Q M Je, de Quartel, Linda, de Jong, Joan, Meyering, Maaike, Falkenburg, J H Fred, Griffioen, Marieke, Osanto, Susanne
    PLoS ONE, 2014;9(1):e85198.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  161. Enhanced expression of the central survival of motor neuron (SMN) protein during the pathogenesis of osteoarthritis.
    Authors: Cucchiarini M, Madry H, Terwilliger E
    J Cell Mol Med, 2014;18(1):115-24.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  162. Modulation of ten-eleven translocation 1 (TET1), Isocitrate Dehydrogenase (IDH) expression, alpha-Ketoglutarate (alpha-KG), and DNA hydroxymethylation levels by interleukin-1beta in primary human chondrocytes.
    Authors: Haseeb A, Makki M, Haqqi T
    J Biol Chem, 2014;289(10):6877-85.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  163. A GPBAR1 (TGR5) small molecule agonist shows specific inhibitory effects on myeloid cell activation in vitro and reduces experimental autoimmune encephalitis (EAE) in vivo.
    Authors: Lewis, Nuruddee, Patnaude, Lori A, Pelletier, Josephin, Souza, Donald J, Lukas, Susan M, King, F James, Hill, Jonathan, Stefanopoulos, Dimitria, Ryan, Kelli, Desai, Sudha, Skow, Donna, Kauschke, Stefan G, Broermann, Andre, Kuzmich, Daniel, Harcken, Christia, Hickey, Eugene R, Modis, Louise K
    PLoS ONE, 2014;9(6):e100883.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  164. Soluble CEACAM8 interacts with CEACAM1 inhibiting TLR2-triggered immune responses.
    Authors: Singer B, Opp L, Heinrich A, Schreiber F, Binding-Liermann R, Berrocal-Almanza L, Heyl K, Muller M, Weimann A, Zweigner J, Slevogt H
    PLoS ONE, 2014;9(4):e94106.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  165. Tumor necrosis factor stimulates osteoclastogenesis from human bone marrow cells under hypoxic conditions.
    Authors: Nomura T, Aoyama M, Waguri-Nagaya Y, Goto Y, Suzuki M, Miyazawa K, Asai K, Goto S
    Exp Cell Res, 2014;321(2):167-77.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  166. Functional effects of Toll-like receptor (TLR)3, 7, 9, RIG-I and MDA-5 stimulation in nasal epithelial cells.
    Authors: Tengroth L, Millrud C, Kvarnhammar A, Kumlien Georen S, Latif L, Cardell L
    PLoS ONE, 2014;9(6):e98239.
    Species: Human
    Sample Type: Whole Tissue
    Application: Bioassay
  167. Glucocorticoid-induced reversal of interleukin-1beta-stimulated inflammatory gene expression in human oviductal cells.
    Authors: Backman S, Kollara A, Haw R, Stein L, Brown T
    PLoS ONE, 2014;9(5):e97997.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  168. TNF-alpha induces CXCL1 chemokine expression and release in human vascular endothelial cells in vitro via two distinct signaling pathways.
    Authors: Lo H, Lai T, Li C, Wu W
    Acta Pharmacol Sin, 2014;35(3):339-50.
  169. A composite model of the human postcapillary venule for investigation of microvascular leukocyte recruitment.
    Authors: Lauridsen H, Pober J, Gonzalez A
    FASEB J, 2014;28(3):1166-80.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  170. The in vitro pharmacology of GS-5759, a novel bifunctional phosphodiesterase 4 inhibitor and long acting beta2-adrenoceptor agonist.
    Authors: Tannheimer S, Sorensen E, Cui Z, Kim M, Patel L, Baker W, Phillips G, Wright C, Salmon M
    J Pharmacol Exp Ther, 2014;349(1):85-93.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  171. A splicing variant of NME1 negatively regulates NF-kappaB signaling and inhibits cancer metastasis by interacting with IKKbeta.
    Authors: You D, Park C, Lee H, Moon M, Kang J, Lee C, Oh S, Ahn C, Seong J, Hwang J
    J Biol Chem, 2014;289(25):17709-20.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  172. Overexpression of progelatinase B/proMMP-9 affects migration regulatory pathways and impairs chronic lymphocytic leukemia cell homing to bone marrow and spleen.
    Authors: Bailon E, Ugarte-Berzal E, Amigo-Jimenez I, Van den Steen P, Opdenakker G, Garcia-Marco J, Garcia-Pardo A
    J Leukoc Biol, 2014;96(2):185-99.
    Species: Human
    Sample Type: N/A
    Application: Not Specified
  173. Tumor necrosis factor (TNF)-alpha induction of CXCL10 in endothelial cells requires protein arginine methyltransferase 5 (PRMT5)-mediated nuclear factor (NF)-kappaB p65 methylation.
    Authors: Harris D, Bandyopadhyay S, Maxwell T, Willard B, DiCorleto P
    J Biol Chem, 2014;289(22):15328-39.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  174. Plasma cells in the mucosa of patients with inflammatory bowel disease produce granzyme B and possess cytotoxic activities.
    Authors: Cupi M, Sarra M, Marafini I, Monteleone I, Franze E, Ortenzi A, Colantoni A, Sica G, Sileri P, Rosado M, Carsetti R, MacDonald T, Pallone F, Monteleone G
    J Immunol, 2014;192(12):6083-91.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  175. IDO-independent suppression of T cell effector function by IFN-gamma-licensed human mesenchymal stromal cells.
    Authors: Chinnadurai R, Copland I, Patel S, Galipeau J
    J Immunol, 2014;192(4):1491-501.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  176. Luteolin inhibits human keratinocyte activation and decreases NF-kappaB induction that is increased in psoriatic skin.
    Authors: Weng Z, Patel A, Vasiadi M, Therianou A, Theoharides T
    PLoS ONE, 2014;9(2):e90739.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  177. MicroRNA-155 negatively affects blood-brain barrier function during neuroinflammation.
    Authors: Lopez-Ramirez M, Wu D, Pryce G, Simpson J, Reijerkerk A, King-Robson J, Kay O, de Vries H, Hirst M, Sharrack B, Baker D, Male D, Michael G, Romero I
    FASEB J, 2014;28(6):2551-65.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  178. Interleukin-2 alters distribution of CD144 (VE-cadherin) in endothelial cells.
    Authors: Kim, Dae Won, Zloza, Andrew, Broucek, Joseph, Schenkel, Jason M, Ruby, Carl, Samaha, Georges, Kaufman, Howard L
    J Transl Med, 2014;12(0):113.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  179. Role and regulation of PDGFRalpha signaling in liver development and regeneration.
    Authors: Awuah P, Nejak-Bowen K, Monga S
    Am J Pathol, 2013;182(5):1648-58.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  180. Interferon-beta induces distinct gene expression response patterns in human monocytes versus T cells.
    Authors: Henig N, Avidan N, Mandel I, Staun-Ram E, Ginzburg E, Paperna T, Pinter R, Miller A
    PLoS ONE, 2013;8(4):e62366.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  181. A GM-CSF/IL-33 pathway facilitates allergic airway responses to sub-threshold house dust mite exposure.
    Authors: Llop-Guevara A, Chu D, Walker T, Goncharova S, Fattouh R, Silver J, Moore C, Xie J, O'Byrne P, Coyle A, Kolbeck R, Humbles A, Stampfli M, Jordana M
    PLoS ONE, 2013;9(2):e88714.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  182. The microvesicle component of HIV-1 inocula modulates dendritic cell infection and maturation and enhances adhesion to and activation of T lymphocytes.
    Authors: Mercier S, Donaghy H, Botting R, Turville S, Harman A, Nasr N, Ji H, Kusebauch U, Mendoza L, Shteynberg D, Sandgren K, Simpson R, Moritz R, Cunningham A
    PLoS Pathog, 2013;9(10):e1003700.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  183. Protein carbamylation predicts mortality in ESRD.
    Authors: Koeth R, Kalantar-Zadeh K, Wang Z, Fu X, Tang W, Hazen S
    , 2013;0(0):.
    Species: Human
    Sample Type: Recombinant Protein
    Application: ELISA Standard
  184. Cytosolic phospholipase A2 regulates TNF-induced production of joint destructive effectors in synoviocytes.
    Authors: Sommerfelt R, Feuerherm A, Jones K, Johansen B
    PLoS ONE, 2013;8(12):e83555.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  185. NF-kappaB-induced IL-6 ensures STAT3 activation and tumor aggressiveness in glioblastoma.
    Authors: McFarland B, Hong S, Rajbhandari R, Twitty G, Gray G, Yu H, Benveniste E, Nozell S
    PLoS ONE, 2013;8(11):e78728.
    Species: Human
    Sample Type: Whole Cells
    Application: cell culture
  186. A mammalian pseudogene lncRNA at the interface of inflammation and anti-inflammatory therapeutics.
    Authors: Rapicavoli N, Qu K, Zhang J, Mikhail M, Laberge R, Chang H
    Elife, 2013;2(0):e00762.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  187. MUC1 and MUC13 differentially regulate epithelial inflammation in response to inflammatory and infectious stimuli.
    Authors: Sheng Y, Triyana S, Wang R, Das I, Gerloff K, Florin T, Sutton P, McGuckin M
    Mucosal Immunol, 2013;6(3):557-68.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  188. Attenuated TGF-beta1 responsiveness of dendritic cells and their precursors in atopic dermatitis.
    Authors: Peng W, Maintz L, Allam J, Novak N
    Eur J Immunol, 2013;43(5):1374-82.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  189. Long-term incubation with proteasome inhibitors (PIs) induces IkappaBalpha degradation via the lysosomal pathway in an IkappaB kinase (IKK)-dependent and IKK-independent manner.
    Authors: Lee K, Jeong J, Yoo C
    J Biol Chem, 2013;288(45):32777-86.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  190. A Lectin-EGF antibody promotes regulatory T cells and attenuates nephrotoxic nephritis via DC-SIGN on dendritic cells.
    Authors: Cai, Minchao, Wu, Jing, Mao, Chaoming, Ren, Jianmin, Li, Pu, Li, Xiao, Zhong, Jiuchang, Xu, Chundi, Zhou, Tong
    J Transl Med, 2013;11(0):103.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  191. Type I interferon upregulates Bak and contributes to T cell loss during human immunodeficiency virus (HIV) infection.
    Authors: Fraietta J, Mueller Y, Yang G, Boesteanu A, Gracias D, Do D, Hope J, Kathuria N, McGettigan S, Lewis M, Giavedoni L, Jacobson J, Katsikis P
    PLoS Pathog, 2013;9(10):e1003658.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  192. The internal architecture of leukocyte lipid body organelles captured by three-dimensional electron microscopy tomography.
    Authors: Melo, Rossana, Paganoti, Guillher, Dvorak, Ann M, Weller, Peter F
    PLoS ONE, 2013;8(3):e59578.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  193. IFN-alpha induces APOBEC3G, F, and A in immature dendritic cells and limits HIV-1 spread to CD4+ T cells.
    Authors: Mohanram V, Skold A, Bachle S, Pathak S, Spetz A
    J Immunol, 2013;190(7):3346-53.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  194. Tumor necrosis factor alpha-induced microRNA-18a activates rheumatoid arthritis synovial fibroblasts through a feedback loop in NF-kappaB signaling.
    Authors: Trenkmann M, Brock M, Gay R, Michel B, Gay S, Huber L
    Arthritis Rheum, 2013;65(4):916-27.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  195. 12/15-lipoxygenase expressed in non-epithelial cells causes airway epithelial injury in asthma.
    Authors: Mabalirajan U, Rehman R, Ahmad T, Kumar S, Leishangthem G, Singh S, Dinda A, Biswal S, Agrawal A, Ghosh B
    Sci Rep, 2013;3(0):1540.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  196. TCR-driven transendothelial migration of human effector memory CD4 T cells involves Vav, Rac, and myosin IIA.
    Authors: Manes, Thomas D, Pober, Jordan S
    J Immunol, 2013;190(7):3079-88.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  197. Regulation of development of CD56 bright CD11c + NK-like cells with helper function by IL-18.
    Authors: Li W, Okuda A, Yamamoto H, Yamanishi K, Terada N, Yamanishi H, Tanaka Y, Okamura H
    PLoS ONE, 2013;8(12):e82586.
    Species: Human
    Sample Type: N/A
    Application: Not Specified
  198. IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.
    Authors: Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, Behar S
    J Immunol, 2013;190(8):4196-204.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  199. Reduced BMPR2 expression induces GM-CSF translation and macrophage recruitment in humans and mice to exacerbate pulmonary hypertension.
    Authors: Sawada H, Saito T, Nickel N, Alastalo T, Glotzbach J, Chan R, Haghighat L, Fuchs G, Januszyk M, Cao A, Lai Y, Perez V, Kim Y, Wang L, Chen P, Spiekerkoetter E, Mitani Y, Gurtner G, Sarnow P, Rabinovitch M
    J Exp Med, 2013;211(2):263-80.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  200. The PI3-kinase delta inhibitor idelalisib (GS-1101) targets integrin-mediated adhesion of chronic lymphocytic leukemia (CLL) cell to endothelial and marrow stromal cells.
    Authors: Fiorcari S, Brown W, McIntyre B, Estrov Z, Maffei R, O'Brien S, Sivina M, Hoellenriegel J, Wierda W, Keating M, Ding W, Kay N, Lannutti B, Marasca R, Burger J
    PLoS ONE, 2013;8(12):e83830.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  201. Integration and regression of implanted engineered human vascular networks during deep wound healing.
    Authors: Hanjaya-Putra D, Shen Y, Wilson A, Fox-Talbot K, Khetan S, Burdick J, Steenbergen C, Gerecht S
    Stem Cells Transl Med, 2013;2(4):297-306.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  202. Outer membrane vesicles derived from Escherichia coli up-regulate expression of endothelial cell adhesion molecules in vitro and in vivo.
    Authors: Kim J, Yoon Y, Lee J, Choi E, Yi N, Park K, Park J, Lotvall J, Kim Y, Gho Y
    PLoS ONE, 2013;8(3):e59276.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  203. Magnolol inhibits migration of vascular smooth muscle cells via cytoskeletal remodeling pathway to attenuate neointima formation.
    Authors: Karki R, Kim S, Kim D
    Exp Cell Res, 2013;319(20):3238-50.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  204. Keratinocyte overexpression of IL-17C promotes psoriasiform skin inflammation.
    Authors: Johnston A, Fritz Y, Dawes S, Diaconu D, Al-Attar P, Guzman A, Chen C, Fu W, Gudjonsson J, McCormick T, Ward N
    J Immunol, 2013;190(5):2252-62.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  205. Fetal fibronectin signaling induces matrix metalloproteases and cyclooxygenase-2 (COX-2) in amnion cells and preterm birth in mice.
    Authors: Mogami H, Kishore A, Shi H, Keller P, Akgul Y, Word R
    J Biol Chem, 2013;288(3):1953-66.
    Species: Human
    Sample Type: Whole Cells
    Application: Media Supplement - Cell Prep
  206. In vivo modulation of the inflammatory response by nonsteroidal antiinflammatory drug-related compounds that trigger L-selectin shedding.
    Authors: Herrera-Garcia A, Dominguez-Luis M, Arce-Franco M, Lopez-Fernandez J, Feria M, Barreiro O, Sanchez-Madrid F, Diaz-Gonzalez F
    Eur J Immunol, 2013;43(1):55-64.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  207. A20/TNFAIP3 inhibits NF-kappaB activation induced by the Kaposi's sarcoma-associated herpesvirus vFLIP oncoprotein.
    Authors: Sakakibara S, Espigol-Frigole G, Gasperini P, Uldrick T, Yarchoan R, Tosato G
    Oncogene, 2013;32(10):1223-32.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  208. Targeting protein kinase CK2 suppresses prosurvival signaling pathways and growth of glioblastoma.
    Authors: Zheng Y, McFarland B, Drygin D, Yu H, Bellis S, Kim H, Bredel M, Benveniste E
    Clin Cancer Res, 2013;19(23):6484-94.
    Species: Human
    Sample Type: Whole Cells
    Application: cell culture
  209. Reference range and short- and long-term biological variation of interleukin (IL)-6, IL-17A and tissue necrosis factor-alpha using high sensitivity assays.
    Authors: Todd J, Simpson P, Estis J, Torres V, Wub A
    Cytokine, 2013;64(3):660-5.
    Species: Human
    Sample Type: Plasma
    Application: ELISA Standard
  210. Endothelial endoglin is involved in inflammation: role in leukocyte adhesion and transmigration.
    Authors: Rossi E, Sanz-Rodriguez F, Eleno N, Duwell A, Blanco F, Langa C, Botella L, Cabanas C, Lopez-Novoa J, Bernabeu C
    Blood, 2013;121(2):403-15.
  211. Comparison of drug and cell-based delivery: engineered adult mesenchymal stem cells expressing soluble tumor necrosis factor receptor II prevent arthritis in mouse and rat animal models.
    Authors: Liu L, Wang G, Hendricks K, Lee K, Bohnlein E, Junker U, Mosca J
    Stem Cells Transl Med, 2013;2(5):362-75.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  212. Discovery and preclinical characterization of novel small molecule TRK and ROS1 tyrosine kinase inhibitors for the treatment of cancer and inflammation.
    Authors: Narayanan R, Yepuru M, Coss C, Wu Z, Bauler M, Barrett C, Mohler M, Wang Y, Kim J, Snyder L, He Y, Levy N, Miller D, Dalton J
    PLoS ONE, 2013;8(12):e83380.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  213. The SDF-1α/CXCR4 Axis is Required for Proliferation and Maturation of Human Fetal Pancreatic Endocrine Progenitor Cells.
    Authors: Kayali AG, Lopez AD, Hao E, Hinton A, Hayek A, King CC
    PLoS ONE, 2012;7(6):e38721.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  214. Constitutive expression of inter-alpha-inhibitor (IalphaI) family proteins and tumor necrosis factor-stimulated gene-6 (TSG-6) by human amniotic membrane epithelial and stromal cells supporting formation of the heavy chain-hyaluronan (HC-HA) complex.
    Authors: Zhang S, He H, Day AJ, Tseng SC
    J. Biol. Chem., 2012;287(15):12433-44.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  215. Role of interleukin-32 in Helicobacter pylori-induced gastric inflammation.
    Authors: Sakitani K, Hirata Y, Hayakawa Y, Serizawa T, Nakata W, Takahashi R, Kinoshita H, Sakamoto K, Nakagawa H, Akanuma M, Yoshida H, Maeda S, Koike K
    Infect Immun, 2012;80(11):3795-803.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  216. Generation of allo-restricted peptide-specific T cells using RNA-pulsed dendritic cells: A three phase experimental procedure.
    Authors: Wilde S, Geiger C, Milosevic S, Mosetter B, Eichenlaub S, Schendel D
    Oncoimmunology, 2012;1(2):129-140.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  217. AAV2/IL-12 gene delivery into dendritic cells (DC) enhances CTL stimulation above other IL-12 applications: Evidence for IL-12 intracrine activity in DC.
    Authors: You C, Shi M, Liu Y, Cao M, Luo R, Hermonat P
    Oncoimmunology, 2012;1(6):847-855.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  218. The C-type Lectin Receptor CLECSF8 (CLEC4D) Is Expressed by Myeloid Cells and Triggers Cellular Activation through Syk Kinase.
    Authors: Graham LM, Gupta V, Schafer G, Reid DM, Kimberg M, Dennehy KM, Hornsell WG, Guler R, Campanero-Rhodes MA, Palma AS, Feizi T, Kim SK, Sobieszczuk P, Willment JA, Brown GD
    J. Biol. Chem., 2012;287(31):25964-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  219. Cross-presentation of tumour antigens by human induced pluripotent stem cell-derived CD141(+)XCR1+ dendritic cells.
    Gene Ther, 2012;19(10):1035-40.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  220. Kinome-wide functional genomics screen reveals a novel mechanism of TNFα-induced nuclear accumulation of the HIF-1α transcription factor in cancer cells.
    Authors: Schoolmeesters A, Brown DD, Fedorov Y
    PLoS ONE, 2012;7(2):e31270.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  221. Detecting T-cell reactivity to whole cell vaccines: Proof of concept analysis of T-cell response to K562 cell antigens in CML patients.
    Authors: Brusic, Ana, Hainz, Ursula, Wadleigh, Martha, Neuberg, Donna, Su, Mei, Canning, Christin, Deangelo, Daniel J, Stone, Richard, Lee, Jeng-Shi, Mulligan, Richard, Ritz, Jerome, Dranoff, Glenn, Sasada, Tetsuro, Wu, Catherin
    Oncoimmunology, 2012;1(7):1095-1103.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  222. Mycobacterium tuberculosis infection and tissue factor expression in macrophages.
    Authors: Kothari H, Rao L, Vankayalapati R, Pendurthi U
    PLoS ONE, 2012;7(9):e45700.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  223. Regulation of IL-33 expression by IFN-gamma and tumor necrosis factor-alpha in normal human epidermal keratinocytes.
    J. Invest. Dermatol., 2012;132(11):2593-600.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  224. Nitric oxide-producing myeloid-derived suppressor cells inhibit vascular E-selectin expression in human squamous cell carcinomas.
    J. Invest. Dermatol., 2012;132(11):2642-51.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  225. Notch is active in Langerhans cell histiocytosis and confers pathognomonic features on dendritic cells.
    Authors: Hutter, Caroline, Kauer, Max, Simonitsch-Klupp, Ingrid, Jug, Gunhild, Schwentner, Raphaela, Leitner, Judith, Bock, Peter, Steinberger, Peter, Bauer, Wolfgang, Carlesso, Nadia, Minkov, Milen, Gadner, Helmut, Stingl, Georg, Kovar, Heinrich, Kriehuber, Ernst
    Blood, 2012;120(26):5199-208.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  226. Pentraxin 3 (PTX3) expression in allergic asthmatic airways: role in airway smooth muscle migration and chemokine production.
    Authors: Zhang J, Shan L, Koussih L, Redhu NS, Halayko AJ, Chakir J, Gounni AS
    PLoS ONE, 2012;7(4):e34965.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  227. Immunodeficiency, autoinflammation and amylopectinosis in humans with inherited HOIL-1 and LUBAC deficiency.
    Authors: Boisson B, Laplantine E, Prando C, Giliani S, Israelsson E, Xu Z, Abhyankar A, Israel L, Trevejo-Nunez G, Bogunovic D, Cepika A, MacDuff D, Chrabieh M, Hubeau M, Bajolle F, Debre M, Mazzolari E, Vairo D, Agou F, Virgin H, Bossuyt X, Rambaud C, Facchetti F, Bonnet D, Quartier P, Fournet J, Pascual V, Chaussabel D, Notarangelo L, Puel A, Israel A, Casanova J, Picard C
    Nat Immunol, 2012;13(12):1178-86.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  228. Osteoblast-like differentiation of cultured human coronary artery smooth muscle cells by bone morphogenetic protein endothelial cell precursor-derived regulator (BMPER).
    Authors: Satomi-Kobayashi S, Kinugasa M, Kobayashi R, Hatakeyama K, Kurogane Y, Ishida T, Emoto N, Asada Y, Takai Y, Hirata K, Rikitake Y
    J Biol Chem, 2012;287(36):30336-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  229. Daily exposure to dust alters innate immunity.
    Authors: Sahlander K, Larsson K, Palmberg L
    PLoS ONE, 2012;7(2):e31646.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  230. Targeting of macrophage galactose-type C-type lectin (MGL) induces DC signaling and activation.
    Authors: Napoletano C, Zizzari IG, Rughetti A, Rahimi H, Irimura T, Clausen H, Wandall HH, Belleudi F, Bellati F, Pierelli L, Frati L, Nuti M
    Eur. J. Immunol., 2012;42(4):936-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  231. Herpes simplex encephalitis in children with autosomal recessive and dominant TRIF deficiency.
    Authors: Sancho-Shimizu V, Perez de Diego R, Lorenzo L, Halwani R, Alangari A, Israelsson E, Fabrega S, Cardon A, Maluenda J, Tatematsu M, Mahvelati F, Herman M, Ciancanelli M, Guo Y, AlSum Z, Alkhamis N, Al-Makadma AS, Ghadiri A, Boucherit S, Plancoulaine S, Picard C, Rozenberg F, Tardieu M, Lebon P, Jouanguy E, Rezaei N, Seya T, Matsumoto M, Chaussabel D, Puel A, Zhang SY, Abel L, Al-Muhsen S, Casanova JL
    J. Clin. Invest., 2011;121(12):4889-902.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  232. C-reactive protein promotes diabetic kidney disease in a mouse model of type 1 diabetes.
    Authors: Liu F, Chen HY, Huang XR, Chung AC, Zhou L, Fu P, Szalai AJ, Lan HY
    Diabetologia, 2011;54(10):2713-23.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  233. Effects of TLR agonists on maturation and function of 3-day dendritic cells from AML patients in complete remission.
    Authors: Beck B, Dorfel D, Lichtenegger FS, Geiger C, Lindner L, Merk M, Schendel DJ, Subklewe M
    J Transl Med, 2011;9(0):151.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  234. IL-1F5, -F6, -F8, and -F9: A Novel IL-1 Family Signaling System That Is Active in Psoriasis and Promotes Keratinocyte Antimicrobial Peptide Expression.
    Authors: Johnston A, Xing X, Guzman AM, Riblett M, Loyd CM, Ward NL, Wohn C, Prens EP, Wang F, Maier LE, Kang S, Voorhees JJ, Elder JT, Gudjonsson JE
    J. Immunol., 2011;186(4):2613-22.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  235. Expression and regulation of CCL15 by human airway smooth muscle cells.
    Authors: Joubert P, Lajoie-Kadoch S, Wellemans V, Létuvé S, Tulic MK, Halayko AJ, Hamid Q
    Clin. Exp. Allergy, 2011;42(1):85-94.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  236. Bacterial lipoprotein TLR2 agonists broadly modulate endothelial function and coagulation pathways in vitro and in vivo.
    Authors: Shin HS, Xu F, Bagchi A, Herrup E, Wilhelmsen K
    J. Immunol., 2011;186(2):1119-30.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  237. HIV-1 replication in Langerhans and interstitial dendritic cells is inhibited by neutralizing and Fc-mediated inhibitory antibodies.
    Authors: Peressin M, Holl V, Schmidt S, Decoville T, Mirisky D, Lederle A, Delaporte M, Xu K, Aubertin AM, Moog C
    J. Virol., 2011;85(2):1077-85.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  238. LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism.
    Authors: Tiller G, Laumen H, Fischer-Posovszky P, Finck A, Skurk T, Keuper M, Brinkmann U, Wabitsch M, Link D, Hauner H
    Int J Obes (Lond), 2011;35(2):208-16.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  239. IL-17A and TNF-alpha Exert Synergistic Effects on Expression of CXCL5 by Alveolar Type II Cells In Vivo and In Vitro.
    Authors: Liu Y, Mei J, Gonzales L, Yang G, Dai N, Wang P, Zhang P, Favara M, Malcolm KC, Guttentag S, Worthen GS
    J. Immunol., 2011;186(5):3197-205.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  240. Focal increases of fetal macrophages in placentas from pregnancies with histological chorioamnionitis: potential role of fibroblast monocyte chemotactic protein-1.
    Authors: Toti P, Arcuri F, Tang Z, Schatz F, Zambrano E, Mor G, Niven-Fairchild T, Abrahams VM, Krikun G, Lockwood CJ, Guller S
    Am. J. Reprod. Immunol., 2011;65(5):470-9.
  241. Increased expression of matrix metalloproteinase-1 in systemic vessels of preeclamptic women: a critical mediator of vascular dysfunction.
    Authors: Estrada-Gutierrez G, Cappello RE, Mishra N, Romero R, Strauss JF, Walsh SW
    Am. J. Pathol., 2011;178(1):451-60.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  242. T-helper cell type 2 (Th2) memory T cell-potentiating cytokine IL-25 has the potential to promote angiogenesis in asthma.
    Authors: Corrigan CJ, Wang W, Meng Q, Fang C, Wu H, Reay V, Lv Z, Fan Y, An Y, Wang YH, Liu YJ, Lee TH, Ying S
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(4):1579-84.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  243. BMP activity controlled by BMPER regulates the proinflammatory phenotype of endothelium.
    Authors: Helbing T, Rothweiler R, Ketterer E, Goetz L, Heinke J, Grundmann S, Duerschmied D, Patterson C, Bode C, Moser M
    Blood, 2011;118(18):5040-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  244. Inter-regulation of Th17 cytokines and the IL-36 cytokines in vitro and in vivo: implications in psoriasis pathogenesis.
    Authors: Carrier Y, Ma HL, Ramon HE, Napierata L, Small C, O'Toole M, Young DA, Fouser LA, Nickerson-Nutter C, Collins M, Dunussi-Joannopoulos K, Medley QG
    J. Invest. Dermatol., 2011;131(12):2428-37.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  245. Dimethyl fumarate, an immune modulator and inducer of the antioxidant response, suppresses HIV replication and macrophage-mediated neurotoxicity: a novel candidate for HIV neuroprotection.
    Authors: Cross SA, Cook DR, Chi AW, Vance PJ, Kolson LL, Wong BJ, Jordan-Sciutto KL, Kolson DL
    J. Immunol., 2011;187(10):5015-25.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  246. Monocytic microparticles activate endothelial cells in an IL-1{beta}-dependent manner.
    Authors: Wang JG, Williams JC, Davis BK, Jacobson K, Doerschuk CM, Ting JP, Mackman N
    Blood, 2011;118(8):2366-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  247. IL-17C regulates the innate immune function of epithelial cells in an autocrine manner.
    Authors: Ramirez-Carrozzi V, Sambandam A, Luis E
    Nat. Immunol., 2011;12(12):1159-66.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  248. Cadherin-11 regulates fibroblast inflammation.
    Authors: Chang SK, Noss EH, Chen M, Gu Z, Townsend K, Grenha R, Leon L, Lee SY, Lee DM, Brenner MB
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(20):8402-7.
  249. Complement Receptor Mac-1 Is an Adaptor for NB1 (CD177)-mediated PR3-ANCA Neutrophil Activation.
    Authors: Jerke U, Rolle S, Dittmar G, Bayat B, Santoso S, Sporbert A, Luft F, Kettritz R
    J. Biol. Chem., 2011;286(9):7070-81.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  250. Evidence for altered Wnt signaling in psoriatic skin.
    Authors: Gudjonsson JE, Johnston A, Stoll SW
    J. Invest. Dermatol., 2010;130(7):1849-59.
    Species: Human
    Sample Type: Whole Cells
  251. Increased B7-H1 expression on dendritic cells correlates with programmed death 1 expression on T cells in simian immunodeficiency virus-infected macaques and may contribute to T cell dysfunction and disease progression.
    Authors: Xu H, Wang X, Pahar B
    J. Immunol., 2010;185(12):7340-8.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Bioassay
  252. Hydroxylase inhibition abrogates TNF-alpha-induced intestinal epithelial damage by hypoxia-inducible factor-1-dependent repression of FADD.
    Authors: Hindryckx P, De Vos M, Jacques P, Ferdinande L, Peeters H, Olievier K, Bogaert S, Brinkman B, Vandenabeele P, Elewaut D, Laukens D
    J. Immunol., 2010;185(10):6306-16.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  253. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
    Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
    Mucosal Immunol, 2010;3(1):40-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  254. IL-10 suppresses Th17 cells and promotes regulatory T cells in the CD4+ T cell population of rheumatoid arthritis patients.
    Authors: Heo YJ, Joo YB, Oh HJ, Park MK, Heo YM, Cho ML, Kwok SK, Ju JH, Park KS, Cho SG, Park SH, Kim HY, Min JK
    Immunol. Lett., 2010;127(2):150-6.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  255. Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis.
    Authors: Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
    J. Immunol., 2010;184(0):5263-70.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  256. B7-h3 augments the inflammatory response and is associated with human sepsis.
    Authors: Zhang G, Wang J, Kelly J
    J. Immunol., 2010;185(6):3677-84.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  257. IFN-gamma generates maturation-arrested dendritic cells that induce T cell hyporesponsiveness independent of Foxp3+ T-regulatory cell generation.
    Authors: Rojas D, Krishnan R,
    Immunol. Lett., 2010;132(1):31-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  258. Inflammation-induced secretion of CCL21 in lymphatic endothelium is a key regulator of integrin-mediated dendritic cell transmigration.
    Authors: Johnson LA, Jackson DG
    Int. Immunol., 2010;22(10):839-49.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  259. IL-17 amplifies human contact hypersensitivity by licensing hapten nonspecific Th1 cells to kill autologous keratinocytes.
    Authors: Pennino D, Eyerich K, Scarponi C, Carbone T, Eyerich S, Nasorri F, Garcovich S, Traidl-Hoffmann C, Albanesi C, Cavani A
    J. Immunol., 2010;184(9):4880-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  260. Chemerin expression marks early psoriatic skin lesions and correlates with plasmacytoid dendritic cell recruitment.
    Authors: Albanesi C, Scarponi C, Pallotta S, Daniele R, Bosisio D, Madonna S, Fortugno P, Gonzalvo-Feo S, Franssen JD, Parmentier M, De Pita O, Girolomoni G, Sozzani S
    J. Exp. Med., 2009;206(1):249-58.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  261. Human bronchial intraepithelial T cells produce interferon-gamma and stimulate epithelial cells.
    Authors: Hirosako S, Goto E, Fujii K, Tsumori K, Hirata N, Tsumura S, Kamohara H, Kohrogi H
    Clin. Exp. Immunol., 2009;155(2):266-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  262. The E-selectin ligand basigin/CD147 is responsible for neutrophil recruitment in renal ischemia/reperfusion.
    Authors: Kato N, Yuzawa Y, Kosugi T
    J. Am. Soc. Nephrol., 2009;20(7):1565-76.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  263. Ethyl pyruvate decreases HMGB1 release and ameliorates murine colitis.
    Authors: Dave SH, Tilstra JS, Matsuoka K, Li F, DeMarco RA, Beer-Stolz D, Sepulveda AR, Fink MP, Lotze MT, Plevy SE
    J. Leukoc. Biol., 2009;86(3):633-43.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  264. TLR-stimulated CD34 stem cell-derived human skin-like and monocyte-derived dendritic cells fail to induce Th17 polarization of naive T cells but do stimulate Th1 and Th17 memory responses.
    Authors: Duraisingham SS, Hornig J, Gotch F, Patterson S
    J. Immunol., 2009;183(4):2242-51.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  265. Cytokine milieu modulates release of thymic stromal lymphopoietin from human keratinocytes stimulated with double-stranded RNA.
    Authors: Kinoshita H, Takai T, Le TA, Kamijo S, Wang XL, Ushio H, Hara M, Kawasaki J, Vu AT, Ogawa T, Gunawan H, Ikeda S, Okumura K, Ogawa H
    J. Allergy Clin. Immunol., 2009;123(1):179-86.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  266. The Th17 cytokine IL-22 induces IL-20 production in keratinocytes: a novel immunological cascade with potential relevance in psoriasis.
    Authors: Wolk K, Witte E, Warszawska K, Schulze-Tanzil G, Witte K, Philipp S, Kunz S, Docke WD, Asadullah K, Volk HD, Sterry W, Sabat R
    Eur. J. Immunol., 2009;39(12):3570-81.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  267. Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis.
    Authors: Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, Ohba M, Sueki H, Kokubu F, Hizawa N, Adachi M, Huang SK, Iijima M
    J. Invest. Dermatol., 2009;129(3):650-6.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  268. Production of interleukin 22 but not interleukin 17 by a subset of human skin-homing memory T cells.
    Authors: Duhen T, Geiger R, Jarrossay D, Lanzavecchia A, Sallusto F
    Nat. Immunol., 2009;10(8):857-63.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  269. Mast cell-dependent contraction of human airway smooth muscle cell-containing collagen gels: influence of cytokines, matrix metalloproteases, and serine proteases.
    Authors: Margulis A, Nocka KH, Brennan AM, Deng B, Fleming M, Goldman SJ, Kasaian MT
    J. Immunol., 2009;183(3):1739-50.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  270. Proteinase-activated receptor (PAR)-2 activation impacts bone resorptive properties of human osteoarthritic subchondral bone osteoblasts.
    Authors: Amiable N, Tat SK, Lajeunesse D, Duval N, Pelletier JP, Martel-Pelletier J, Boileau C
    Bone, 2009;44(6):1143-50.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  271. Human corneal epithelium-derived thymic stromal lymphopoietin links the innate and adaptive immune responses via TLRs and Th2 cytokines.
    Authors: Ma P, Bian F, Wang Z, Zheng X, Chotikavanich S, Pflugfelder SC, Li DQ
    Invest. Ophthalmol. Vis. Sci., 2009;50(6):2702-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  272. Ectopic expression of interleukin-1 receptor type II enhances cell migration through activation of the pre-interleukin 1alpha pathway.
    Authors: Chang SY, Su PF, Lee TC
    Cytokine, 2009;45(1):32-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  273. Inhibition of double-stranded RNA-induced TSLP in human keratinocytes by glucocorticoids.
    Authors: Le TA, Takai T, Kinoshita H, Suto H, Ikeda S, Okumura K, Ogawa H
    Allergy, 2009;64(8):1231-2.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  274. Inflammatory interaction between LIGHT and proteinase-activated receptor-2 in endothelial cells: potential role in atherogenesis.
    Authors: Sandberg WJ, Halvorsen B, Yndestad A, Smith C, Otterdal K, Brosstad FR, Froland SS, Olofsson PS, Damas JK, Gullestad L, Hansson GK, Oie E, Aukrust P
    Circ. Res., 2009;104(1):60-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  275. Vascular endothelial growth factor induces protein kinase D-dependent production of proinflammatory cytokines in endothelial cells.
    Authors: Hao Q, Wang L, Tang H
    Am. J. Physiol., Cell Physiol., 2009;296(4):C821-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  276. Adiponectin and functional adiponectin receptor 1 are expressed by airway epithelial cells in chronic obstructive pulmonary disease.
    Authors: Miller M, Cho JY, Pham A, Ramsdell J, Broide DH
    J. Immunol., 2009;182(1):684-91.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  277. Soluble decoy receptor 3 modulates the survival and formation of osteoclasts from multiple myeloma bone disease patients.
    Authors: Colucci S, Brunetti G, Mori G, Oranger A, Centonze M, Mori C, Cantatore FP, Tamma R, Rizzi R, Liso V, Zallone A, Grano M
    Leukemia, 2009;23(11):2139-46.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  278. Interferon-beta treatment in multiple sclerosis attenuates inflammatory gene expression through inducible activity of the phosphatase SHP-1.
    Authors: Christophi GP, Panos M, Hudson CA, Tsikkou C, Mihai C, Mejico LJ, Jubelt B, Massa PT
    Clin. Immunol., 2009;133(1):27-44.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  279. Epidermal receptor activator of NF-kappaB ligand controls Langerhans cells numbers and proliferation.
    Authors: Barbaroux JB, Beleut M, Brisken C, Mueller CG, Groves RW
    J. Immunol., 2008;181(2):1103-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  280. Development and validation of sandwich ELISA microarrays with minimal assay interference.
    Authors: Gonzalez RM, Seurynck-Servoss SL, Crowley SA
    J. Proteome Res., 2008;7(6):2406-14.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  281. Altered expression of MicroRNA in synovial fibroblasts and synovial tissue in rheumatoid arthritis.
    Authors: Stanczyk J, Pedrioli DM, Brentano F, Sanchez-Pernaute O, Kolling C, Gay RE, Detmar M, Gay S, Kyburz D
    Arthritis Rheum., 2008;58(4):1001-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  282. IL-12-impaired and IL-12-secreting dendritic cells produce IL-23 upon CD154 restimulation.
    Authors: Jasny E, Eisenblatter M, Matz-Rensing K, Tenner-Racz K, Tenbusch M, Schrod A, Stahl-Hennig C, Moos V, Schneider T, Racz P, Uberla K, Kaup FJ, Ignatius R
    J. Immunol., 2008;180(10):6629-39.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Bioassay
  283. Activation of the receptor EphB4 by its specific ligand ephrin B2 in human osteoarthritic subchondral bone osteoblasts.
    Authors: Kwan Tat S, Pelletier JP, Amiable N, Boileau C, Lajeunesse D, Duval N, Martel-Pelletier J
    Arthritis Rheum., 2008;58(12):3820-30.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  284. IFN-alpha induces transcription of hypoxia-inducible factor-1alpha to inhibit proliferation of human endothelial cells.
    Authors: Gerber SA, Pober JS
    J. Immunol., 2008;181(2):1052-62.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  285. A novel IL-1 family cytokine, IL-33, potently activates human eosinophils.
    Authors: Cherry WB, Yoon J, Bartemes KR, Iijima K, Kita H
    J. Allergy Clin. Immunol., 2008;121(6):1484-90.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  286. Expression and regulation of CCR1 by airway smooth muscle cells in asthma.
    Authors: Joubert P, Lajoie-Kadoch S, Welman M, Dragon S, Letuvee S, Tolloczko B, Halayko AJ, Gounni AS, Maghni K, Hamid Q
    J. Immunol., 2008;180(2):1268-75.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  287. Maturing dendritic cells are an important source of IL-29 and IL-20 that may cooperatively increase the innate immunity of keratinocytes.
    Authors: Wolk K, Witte K, Witte E, Proesch S, Schulze-Tanzil G, Nasilowska K, Thilo J, Asadullah K, Sterry W, Volk HD, Sabat R
    J. Leukoc. Biol., 2008;83(5):1181-93.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  288. A novel method to establish microglia-free astrocyte cultures: comparison of matrix metalloproteinase expression profiles in pure cultures of astrocytes and microglia.
    Authors: Crocker SJ, Frausto RF, Whitton JL, Milner R
    Glia, 2008;56(0):1187-98.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  289. Tumor necrosis factor-related apoptosis-inducing ligand promotes migration of human bone marrow multipotent stromal cells.
    Authors: Secchiero P, Melloni E, Corallini F, Beltrami AP, Alviano F, Milani D, D'Aurizio F, di Iasio MG, Cesselli D, Bagnara GP, Zauli G
    Stem Cells, 2008;26(11):2955-63.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  290. Nitric oxide attenuates vascular endothelial cadherin-mediated vascular integrity in human chronic inflammation.
    Authors: Hama S, Takeichi O, Fujisaki K, Tanabe N, Maeno M, Ochiai K
    Clin. Exp. Immunol., 2008;154(3):384-90.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  291. Effect of fudosteine on mucin production.
    Authors: Rhee CK, Kang CM, You MB, Yoon HK, Kim YK, Kim KH, Moon HS, Park SH, Song JS
    Eur. Respir. J., 2008;32(5):1195-202.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  292. Evidence of a role for B cell-activating factor of the TNF family in the pathogenesis of chronic rhinosinusitis with nasal polyps.
    Authors: Kato A, Peters A, Suh L, Carter R, Harris KE, Chandra R, Conley D, Grammer LC, Kern R, Schleimer RP
    J. Allergy Clin. Immunol., 2008;121(6):1385-92, 1392.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  293. Expression and potential function of the CXC chemokine CXCL16 in pancreatic ductal adenocarcinoma.
    Authors: Wente MN, Gaida MM, Mayer C, Michalski CW, Haag N, Giese T, Felix K, Bergmann F, Giese NA, Friess H
    Int. J. Oncol., 2008;33(2):297-308.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  294. Upregulation of human cytomegalovirus by HIV type 1 in human lymphoid tissue ex vivo.
    Authors: Biancotto A, Iglehart SJ, Lisco A, Vanpouille C, Grivel JC, Lurain NS, Reichelderfer PS, Margolis LB
    AIDS Res. Hum. Retroviruses, 2008;24(3):453-62.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  295. p38 mitogen-activated protein kinase inhibitor LY2228820 enhances bortezomib-induced cytotoxicity and inhibits osteoclastogenesis in multiple myeloma; therapeutic implications.
    Authors: Ishitsuka K, Hideshima T, Neri P, Vallet S, Shiraishi N, Okawa Y, Shen Z, Raje N, Kiziltepe T, Ocio EM, Chauhan D, Tassone P, Munshi N, Campbell RM, Dios AD, Shih C, Starling JJ, Tamura K, Anderson KC
    Br. J. Haematol., 2008;141(5):598-606.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  296. Expression and role of CCR6/CCL20 chemokine axis in pulmonary sarcoidosis.
    Authors: Facco M, Baesso I, Miorin M, Bortoli M, Cabrelle A, Boscaro E, Gurrieri C, Trentin L, Zambello R, Calabrese F, Cassatella MA, Semenzato G, Agostini C
    J. Leukoc. Biol., 2007;82(4):946-55.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  297. Growth factor induction of Cripto-1 shedding by glycosylphosphatidylinositol-phospholipase D and enhancement of endothelial cell migration.
    Authors: Watanabe K, Bianco C, Strizzi L, Hamada S, Mancino M, Bailly V, Mo W, Wen D, Miatkowski K, Gonzales M, Sanicola M, Seno M, Salomon DS
    J. Biol. Chem., 2007;282(43):31643-55.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  298. SPARC is a VCAM-1 counter-ligand that mediates leukocyte transmigration.
    Authors: Kelly KA, Allport JR, Yu AM, Sinh S, Sage EH, Gerszten RE, Weissleder R
    J. Leukoc. Biol., 2007;81(3):748-56.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  299. Angiopoietin-2 is increased in severe sepsis: correlation with inflammatory mediators.
    Authors: Orfanos SE, Kotanidou A, Glynos C, Athanasiou C, Tsigkos S, Dimopoulou I, Sotiropoulou C, Zakynthinos S, Armaganidis A, Papapetropoulos A, Roussos C
    Crit. Care Med., 2007;35(1):199-206.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  300. Infusion of stably immature monocyte-derived dendritic cells plus CTLA4Ig modulates alloimmune reactivity in rhesus macaques.
    Authors: Zahorchak AF, Kean LS, Tokita D, Turnquist HR, Abe M, Finke J, Hamby K, Rigby MR, Larsen CP, Thomson AW
    Transplantation, 2007;84(2):196-206.
    Species: Primate - Macaca mulatta (Rhesus Macaque)
    Sample Type: Whole Cells
    Application: Bioassay
  301. Abnormal activation and cytokine spectra in lymph nodes of people chronically infected with HIV-1.
    Authors: Biancotto A, Grivel JC, Iglehart SJ, Vanpouille C, Lisco A, Sieg SF, Debernardo R, Garate K, Rodriguez B, Margolis LB, Lederman MM
    Blood, 2007;109(10):4272-9.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  302. Interleukin 31 mediates MAP kinase and STAT1/3 activation in intestinal epithelial cells and its expression is upregulated in inflammatory bowel disease.
    Authors: Dambacher J, Beigel F, Seiderer J, Haller D, Goke B, Auernhammer CJ, Brand S
    Gut, 2007;56(9):1257-65.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  303. HIV-1 pathogenesis differs in rectosigmoid and tonsillar tissues infected ex vivo with CCR5- and CXCR4-tropic HIV-1.
    Authors: Grivel JC, Elliott J, Lisco A, Biancotto A, Condack C, Shattock RJ, McGowan I, Margolis L, Anton P
    AIDS, 2007;21(10):1263-72.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  304. IL-22 induces lipopolysaccharide-binding protein in hepatocytes: a potential systemic role of IL-22 in Crohn's disease.
    Authors: Wolk K, Witte E, Hoffmann U, Doecke WD, Endesfelder S, Asadullah K, Sterry W, Volk HD, Wittig BM, Sabat R
    J. Immunol., 2007;178(9):5973-81.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  305. Crucial role of the protein C pathway in governing microvascular inflammation in inflammatory bowel disease.
    Authors: Scaldaferri F, Sans M, Vetrano S, Graziani C, De Cristofaro R, Gerlitz B, Repici A, Arena V, Malesci A, Panes J, Grinnell BW, Danese S
    J. Clin. Invest., 2007;117(7):1951-60.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  306. Substance P regulates macrophage inflammatory protein 3alpha/chemokine C-C ligand 20 (CCL20) with heme oxygenase-1 in human periodontal ligament cells.
    Authors: Lee SK, Pi SH, Kim SH, Min KS, Lee HJ, Chang HS, Kang KH, Kim HR, Shin HI, Lee SK, Kim EC
    Clin. Exp. Immunol., 2007;150(3):567-75.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  307. Interferon-gamma differentially regulates TGF-beta1 and TGF-beta2 expression in human retinal pigment epithelial cells through JAK-STAT pathway.
    Authors: Nagineni CN, Cherukuri KS, Kutty V, Detrick B, Hooks JJ
    J. Cell. Physiol., 2007;210(1):192-200.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  308. Bradykinin potentiates cytokine-induced prostaglandin biosynthesis in osteoblasts by enhanced expression of cyclooxygenase 2, resulting in increased RANKL expression.
    Authors: Brechter AB, Lerner UH
    Arthritis Rheum., 2007;56(3):910-23.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  309. Tumour necrosis factor-alpha (TNF-alpha) increases nuclear factor kappaB (NFkappaB) activity in and interleukin-8 (IL-8) release from bovine mammary epithelial cells.
    Authors: Fitzgerald DC, Meade KG, McEvoy AN, Lillis L, Murphy EP, Machugh DE, Baird AW
    Vet. Immunol. Immunopathol., 2007;116(1):59-68.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  310. Ultrasensitive flow-based immunoassays using single-molecule counting.
    Authors: Todd J, Freese B, Lu A, Held D, Morey J, Livingston R, Goix P
    Clin. Chem., 2007;53(11):1990-5.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  311. Mitochondrially targeted ceramide LCL-30 inhibits colorectal cancer in mice.
    Authors: Dahm F, Bielawska A, Nocito A, Georgiev P, Szulc ZM, Bielawski J, Jochum W, Dindo D, Hannun YA, Clavien PA
    Br. J. Cancer, 2007;98(1):98-105.
    Species: Mouse
    Sample Type: Whole Cells
    Application: Bioassay
  312. Activation of the p53 pathway down-regulates the osteoprotegerin expression and release by vascular endothelial cells.
    Authors: Secchiero P, Corallini F, Rimondi E, Chiaruttini C, di Iasio MG, Rustighi A, Del Sal G, Zauli G
    Blood, 2007;111(3):1287-94.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  313. The role of vascular cell adhesion molecule 1/ very late activation antigen 4 in endothelial progenitor cell recruitment to rheumatoid arthritis synovium.
    Authors: Silverman MD, Haas CS, Rad AM, Arbab AS, Koch AE
    Arthritis Rheum., 2007;56(6):1817-26.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  314. Inflammatory cytokines stimulate the adhesion of colon carcinoma cells to mesothelial monolayers.
    Authors: van Grevenstein WM, Hofland LJ, van Rossen ME, van Koetsveld PM, Jeekel J, van Eijck CH
    Dig. Dis. Sci., 2007;52(10):2775-83.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  315. Bone morphogenetic protein 7 is elevated in patients with chronic liver disease and exerts fibrogenic effects on human hepatic stellate cells.
    Authors: Tacke F, Gabele E, Bataille F, Schwabe RF, Hellerbrand C, Klebl F, Straub RH, Luedde T, Manns MP, Trautwein C, Brenner DA, Scholmerich J, Schnabl B
    Dig. Dis. Sci., 2007;52(12):3404-15.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  316. Synergism of TNF and IL-1 in the induction of matrix metalloproteinase-3 in trabecular meshwork.
    Authors: Kelley MJ, Rose AY, Song K, Chen Y, Bradley JM, Rookhuizen D, Acott TS
    Invest. Ophthalmol. Vis. Sci., 2007;48(6):2634-43.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  317. Simultaneous induction of apoptotic and survival signaling pathways in macrophage-like THP-1 cells by Shiga toxin 1.
    Authors: Lee SY, Cherla RP, Tesh VL
    Infect. Immun., 2007;75(3):1291-302.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  318. Regulated shedding of transmembrane chemokines by the disintegrin and metalloproteinase 10 facilitates detachment of adherent leukocytes.
    Authors: Hundhausen C, Schulte A, Schulz B, Andrzejewski MG, Schwarz N, von Hundelshausen P, Winter U, Paliga K, Reiss K, Saftig P, Weber C, Ludwig A
    J. Immunol., 2007;178(12):8064-72.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  319. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
    Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
    Blood, 2007;111(8):4096-105.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  320. Role of mesothelial cell-derived granulocyte colony-stimulating factor in interleukin-17-induced neutrophil accumulation in the peritoneum.
    Authors: Witowski J, Ksiazek K, Warnecke C, Kuzlan M, Korybalska K, Tayama H, Wisniewska-Elnur J, Pawlaczyk K, Trominska J, Breborowicz A, Jorres A
    Kidney Int., 2007;71(6):514-25.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  321. LIGHT up-regulated on B lymphocytes and monocytes in rheumatoid arthritis mediates cellular adhesion and metalloproteinase production by synoviocytes.
    Authors: Kang YM, Kim SY, Kang JH
    Arthritis Rheum., 2007;56(4):1106-17.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  322. IFN-gamma alters the response of Borrelia burgdorferi-activated endothelium to favor chronic inflammation.
    Authors: Dame TM, Orenzoff BL, Palmer LE, Furie MB
    J. Immunol., 2007;178(2):1172-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  323. The effects of IL-20 subfamily cytokines on reconstituted human epidermis suggest potential roles in cutaneous innate defense and pathogenic adaptive immunity in psoriasis.
    Authors: Sa SM, Valdez PA, Wu J
    J. Immunol., 2007;178(4):2229-40.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  324. Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression.
    Authors: Kamohara H, Ogawa M, Ishiko T, Sakamoto K, Baba H
    Int. J. Oncol., 2007;30(4):977-83.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  325. Fluorescence single-molecule counting assays for high-sensitivity detection of cytokines and chemokines.
    Authors: Qui H, Ferrell EP, Nolan N, Phelps BH, Tabibiazar R, Whitney DH, Naelfski EA
    Clin. Chem., 2007;53(11):2010-2.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  326. Pharmacologic inhibition of tpl2 blocks inflammatory responses in primary human monocytes, synoviocytes, and blood.
    Authors: Hall JP, Kurdi Y, Hsu S, Cuozzo J, Liu J, Telliez JB, Seidl KJ, Winkler A, Hu Y, Green N, Askew GR, Tam S, Clark JD, Lin LL
    J. Biol. Chem., 2007;282(46):33295-304.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  327. Antiparallel segregation of notch components in the immunological synapse directs reciprocal signaling in allogeneic Th:DC conjugates.
    Authors: Luty WH, Rodeberg D, Parness J, Vyas YM
    J. Immunol., 2007;179(2):819-29.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  328. Calcineurin modulates the catabolic and anabolic activity of chondrocytes and participates in the progression of experimental osteoarthritis.
    Authors: Yoo SA, Park BH, Yoon HJ, Lee JY, Song JH, Kim HA, Cho CS, Kim WU
    Arthritis Rheum., 2007;56(7):2299-311.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  329. Angiotensin II controls occludin function and is required for blood brain barrier maintenance: relevance to multiple sclerosis.
    Authors: Wosik K, Cayrol R, Dodelet-Devillers A, Berthelet F, Bernard M, Moumdjian R, Bouthillier A, Reudelhuber TL, Prat A
    J. Neurosci., 2007;27(34):9032-42.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  330. IL-21 is highly produced in Helicobacter pylori-infected gastric mucosa and promotes gelatinases synthesis.
    Authors: Caruso R, Fina D, Peluso I, Fantini MC, Tosti C, Del Vecchio Blanco G, Paoluzi OA, Caprioli F, Andrei F, Stolfi C, Romano M, Ricci V, MacDonald TT, Pallone F, Monteleone G
    J. Immunol., 2007;178(9):5957-65.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  331. Guinea pig neutrophils infected with Mycobacterium tuberculosis produce cytokines which activate alveolar macrophages in noncontact cultures.
    Authors: Sawant KV, McMurray DN
    Infect. Immun., 2007;75(4):1870-7.
  332. The F11 receptor (F11R/JAM-A) in atherothrombosis: overexpression of F11R in atherosclerotic plaques.
    Authors: Babinska A, Azari BM, Salifu MO, Liu R, Jiang XC, Sobocka MB, Boo D, Al Khoury G, Deitch JS, Marmur JD, Ehrlich YH, Kornecki E
    Thromb. Haemost., 2007;97(2):272-81.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  333. Constitutive and inducible thymic stromal lymphopoietin expression in human airway smooth muscle cells: role in chronic obstructive pulmonary disease.
    Authors: Zhang K, Shan L, Rahman MS, Unruh H, Halayko AJ, Gounni AS
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(2):L375-82.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  334. Dehydroepiandrosterone inhibits the TNF-alpha-induced inflammatory response in human umbilical vein endothelial cells.
    Authors: Gutierrez G, Mendoza C, Zapata E, Montiel A, Reyes E, Montano LF, Lopez-Marure R
    Atherosclerosis, 2007;190(1):90-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  335. Shear flow-dependent integration of apical and subendothelial chemokines in T-cell transmigration: implications for locomotion and the multistep paradigm.
    Authors: Schreiber TH, Shinder V, Cain DW, Alon R, Sackstein R
    Blood, 2007;109(4):1381-6.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  336. Regulation of neuronal pituitary adenylate cyclase-activating polypeptide expression during culture of guinea-pig cardiac ganglia.
    Authors: Girard BM, Young BA, Buttolph TR, White SL, Parsons RL
    Neuroscience, 2007;146(2):584-93.
    Species: Guinea Pig
    Sample Type: Whole Cells
    Application: Bioassay
  337. Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection.
    Authors: Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, Szymkowski DE
    J. Immunol., 2007;179(3):1872-83.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  338. The in vitro migration capacity of human bone marrow mesenchymal stem cells: comparison of chemokine and growth factor chemotactic activities.
    Authors: Ponte AL, Marais E, Gallay N, Langonne A, Delorme B, Herault O, Charbord P, Domenech J
    Stem Cells, 2007;25(7):1737-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  339. IL-1alpha and IL-1beta are endogenous mediators linking cell injury to the adaptive alloimmune response.
    Authors: Rao DA, Tracey KJ, Pober JS
    J. Immunol., 2007;179(10):6536-46.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  340. CD28-mediated regulation of multiple myeloma cell proliferation and survival.
    Authors: Bahlis NJ, King AM, Kolonias D, Carlson LM, Liu HY, Hussein MA, Terebelo HR, Byrne GE, Levine BL, Boise LH, Lee KP
    Blood, 2007;109(11):5002-10.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  341. TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells.
    Authors: Kato A, Favoreto S, Avila PC, Schleimer RP
    J. Immunol., 2007;179(2):1080-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  342. Multiple NF-kappaB and IFN regulatory factor family transcription factors regulate CCL19 gene expression in human monocyte-derived dendritic cells.
    Authors: Pietila TE, Veckman V, Lehtonen A, Lin R, Hiscott J, Julkunen I
    J. Immunol., 2007;178(1):253-61.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  343. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
    Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
    J. Exp. Med., 2006;203(12):2763-77.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  344. Control of matrix metalloproteinase production in human intestinal fibroblasts by interleukin 21.
    Authors: Monteleone G, Caruso R, Fina D, Peluso I, Gioia V, Stolfi C, Fantini MC, Caprioli F, Tersigni R, Alessandroni L, MacDonald TT, Pallone F
    Gut, 2006;55(12):1774-80.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  345. Increased ENA-78 in the follicular fluid of patients with endometriosis.
    Authors: Wunder DM, Mueller MD, Birkhauser MH, Bersinger NA
    Acta Obstet Gynecol Scand, 2006;85(3):336-42.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  346. Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
    Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
    J. Immunol., 2006;177(11):7665-72.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  347. The ascochlorin derivative, AS-6, inhibits TNF-alpha-induced adhesion molecule and chemokine expression in rat vascular smooth muscle cells.
    Authors: Park KG, Lee KM, Magae J, Kim YN, Lee KU, Lee IK
    Life Sci., 2006;80(2):120-6.
    Species: Rat
    Sample Type: Whole Cells
    Application: Bioassay
  348. Spatial compartmentalization of tumor necrosis factor (TNF) receptor 1-dependent signaling pathways in human airway smooth muscle cells. Lipid rafts are essential for TNF-alpha-mediated activation of RhoA but dispensable for the activation of the NF-kappaB and MAPK pathways.
    Authors: Hunter I, Nixon GF
    J. Biol. Chem., 2006;281(45):34705-15.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  349. Normalizing the bone marrow microenvironment with p38 inhibitor reduces multiple myeloma cell proliferation and adhesion and suppresses osteoclast formation.
    Authors: Nguyen AN, Stebbins EG, Henson M, O&amp;amp;apos;Young G, Choi SJ, Quon D, Damm D, Reddy M, Ma JY, Haghnazari E, Kapoun AM, Medicherla S, Protter A, Schreiner GF, Kurihara N, Anderson J, Roodman GD, Navas TA, Higgins LS
    Exp. Cell Res., 2006;312(10):1909-23.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  350. Selective regulation of IL-10 signaling and function by zymosan.
    Authors: Du Z, Kelly E, Mecklenbrauker I, Agle L, Herrero C, Paik P, Ivashkiv LB
    J. Immunol., 2006;176(8):4785-92.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  351. Cigarette smoke synergistically enhances respiratory mucin induction by proinflammatory stimuli.
    Authors: Baginski TK, Dabbagh K, Satjawatcharaphong C, Swinney DC
    Am. J. Respir. Cell Mol. Biol., 2006;35(2):165-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  352. Human intestinal intraepithelial lymphocytes keep TNF alpha levels low by cell uptake and feedback inhibition of transcription.
    Authors: Ebert EC, Mehta V
    Cell. Immunol., 2006;241(1):7-13.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  353. Apoptotic neutrophils release macrophage migration inhibitory factor upon stimulation with tumor necrosis factor-alpha.
    Authors: Daryadel A, Grifone RF, Simon HU, Yousefi S
    J. Biol. Chem., 2006;281(37):27653-61.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  354. LIGHT (TNFSF14), a novel mediator of bone resorption, is elevated in rheumatoid arthritis.
    Authors: Edwards JR, Sun SG, Locklin R, Shipman CM, Adamopoulos IE, Athanasou NA, Sabokbar A
    Arthritis Rheum., 2006;54(5):1451-62.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  355. Regulation of SDF-1 (CXCL12) production by osteoblasts; a possible mechanism for stem cell homing.
    Authors: Jung Y, Wang J, Schneider A, Sun YX, Koh-Paige AJ, Osman NI, McCauley LK, Taichman RS
    Bone, 2006;38(4):497-508.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  356. Nrf2 is a critical regulator of the innate immune response and survival during experimental sepsis.
    Authors: Thimmulappa RK, Lee H, Rangasamy T, Reddy SP, Yamamoto M, Kensler TW, Biswal S
    J. Clin. Invest., 2006;116(4):984-95.
    Species: Mouse
    Sample Type: In Vivo
    Application: In Vivo
  357. Human plasmacytoid predendritic cells activate NK cells through glucocorticoid-induced tumor necrosis factor receptor-ligand (GITRL).
    Authors: Hanabuchi S, Watanabe N, Wang YH, Ito T, Shaw J, Cao W, Qin FX, Liu YJ
    Blood, 2006;107(9):3617-23.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  358. Modeling of tumor necrosis factor receptor superfamily 1A mutants associated with tumor necrosis factor receptor-associated periodic syndrome indicates misfolding consistent with abnormal function.
    Authors: Rebelo SL, Bainbridge SE, Amel-Kashipaz MR, Radford PM, Powell RJ, Todd I, Tighe PJ
    Arthritis Rheum., 2006;54(8):2674-87.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  359. Differential survival of leukocyte subsets mediated by synovial, bone marrow, and skin fibroblasts: site-specific versus activation-dependent survival of T cells and neutrophils.
    Authors: Filer A, Parsonage G, Smith E, Osborne C, Thomas AM, Curnow SJ, Rainger GE, Raza K, Nash GB, Lord J, Salmon M, Buckley CD
    Arthritis Rheum., 2006;54(7):2096-108.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  360. Modulation of neonatal microbial recognition: TLR-mediated innate immune responses are specifically and differentially modulated by human milk.
    Authors: LeBouder E, Rey-Nores JE, Raby AC, Affolter M, Vidal K, Thornton CA, Labeta MO
    J. Immunol., 2006;176(6):3742-52.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  361. Autocrine tumor necrosis factor alpha links endoplasmic reticulum stress to the membrane death receptor pathway through IRE1alpha-mediated NF-kappaB activation and down-regulation of TRAF2 expression.
    Authors: Hu P, Han Z, Couvillon AD, Kaufman RJ, Exton JH
    Mol. Cell. Biol., 2006;26(8):3071-84.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  362. Sepsis and pathophysiology of anthrax in a nonhuman primate model.
    Authors: Stearns-Kurosawa DJ, Lupu F, Taylor FB, Kinasewitz G, Kurosawa S
    Am. J. Pathol., 2006;169(2):433-44.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  363. Development of an in vitro pancreatic tissue model to study regulation of islet neogenesis associated protein expression.
    Authors: Petropavlovskaia M, Makhlin J, Sampalis J, Rosenberg L
    J. Endocrinol., 2006;191(1):65-81.
    Species: Hamster
    Sample Type: Whole Cells
    Application: Bioassay
  364. HIV-1-infected and/or immune activated macrophages regulate astrocyte SDF-1 production through IL-1beta.
    Authors: Peng H, Erdmann N, Whitney N, Dou H, Gorantla S, Gendelman HE, Ghorpade A, Zheng J
    Glia, 2006;54(6):619-29.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  365. Evidence for downregulation of erythropoietin receptor in bone marrow erythroid cells of patients with chronic idiopathic neutropenia.
    Authors: Pontikoglou C, Liapakis G, Pyrovolaki K, Papadakis M, Bux J, Eliopoulos GD, Papadaki HA
    Exp. Hematol., 2006;34(10):1312-22.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  366. Intraarticular corticosteroids decrease synovial RANKL expression in inflammatory arthritis.
    Authors: Makrygiannakis D, af Klint E, Catrina SB, Botusan IR, Klareskog E, Klareskog L, Ulfgren AK, Catrina AI
    Arthritis Rheum., 2006;54(5):1463-72.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  367. Expression of B7-H1 on gastric epithelial cells: its potential role in regulating T cells during Helicobacter pylori infection.
    Authors: Das S, Suarez G, Beswick EJ, Sierra JC, Graham DY, Reyes VE
    J. Immunol., 2006;176(5):3000-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  368. Dendritic cells can turn CD4+ T lymphocytes into vascular endothelial growth factor-carrying cells by intercellular neuropilin-1 transfer.
    Authors: Bourbie-Vaudaine S, Blanchard N, Hivroz C, Romeo PH
    J. Immunol., 2006;177(3):1460-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  369. IL-17E upregulates the expression of proinflammatory cytokines in lung fibroblasts.
    Authors: Létuvé S, Lajoie-Kadoch S, Audusseau S, Rothenberg ME, Fiset PO, Ludwig MS, Hamid Q
    J. Allergy Clin. Immunol., 2006;117(3):590-6.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  370. Aberrant regulation of synovial T cell activation by soluble costimulatory molecules in rheumatoid arthritis.
    Authors: Wan B, Nie H, Liu A, Feng G, He D, Xu R, Zhang Q, Dong C, Zhang JZ
    J. Immunol., 2006;177(12):8844-50.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  371. Interface tissue fibroblasts from loose total hip replacement prosthesis produce receptor activator of nuclear factor-kappaB ligand, osteoprotegerin, and cathepsin K.
    Authors: Mandelin J, Li TF, Hukkanen M, Liljestrom M, Salo J, Santavirta S, Konttinen YT
    J. Rheumatol., 2005;32(4):713-20.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  372. Inhibition of interferon-stimulated JAK-STAT signaling by a tick-borne flavivirus and identification of NS5 as an interferon antagonist.
    Authors: Best SM, Morris KL, Shannon JG, Robertson SJ, Mitzel DN, Park GS, Boer E, Wolfinbarger JB, Bloom ME
    J. Virol., 2005;79(20):12828-39.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Type: Whole Cells
    Application: Bioassay
  373. Effects of the active metabolite of leflunomide, A77 1726, on cytokine release and the MAPK signalling pathway in human rheumatoid arthritis synoviocytes.
    Authors: Vergne-Salle&lt;/LastName&gt;&lt;F P&lt;/Initial, Vergne-Salle P, Leger DY, Bertin P, Treves R, Beneytout JL, Liagre B
    Cytokine, 2005;31(5):335-48.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  374. Dendritic cells induce MUC1 expression and polarization on human T cells by an IL-7-dependent mechanism.
    Authors: Vasir B, Avigan D, Wu Z, Crawford K, Turnquist S, Ren J, Kufe D
    J. Immunol., 2005;174(4):2376-86.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  375. Tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induces rheumatoid arthritis synovial fibroblast proliferation through mitogen-activated protein kinases and phosphatidylinositol 3-kinase/Akt.
    Authors: Morel J, Audo R, Hahne M, Combe B
    J. Biol. Chem., 2005;280(16):15709-18.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  376. Tumor necrosis factor alpha and adiponectin in bone marrow interstitial fluid from patients with acute myeloid leukemia inhibit normal hematopoiesis.
    Authors: Iversen PO, Wiig H
    Clin. Cancer Res., 2005;11(19):6793-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  377. Generation of feline dendritic cells derived from peripheral blood monocytes for in vivo use.
    Authors: Freer G, Matteucci D, Mazzetti P, Bozzacco L, Bendinelli M
    Clin. Diagn. Lab. Immunol., 2005;12(10):1202-8.
    Species: Feline
    Sample Type: Whole Cells
    Application: Bioassay
  378. Modulation of GM-CSF release by enantiomers of beta-agonists in human airway smooth muscle.
    Authors: Ameredes BT, Calhoun WJ
    J. Allergy Clin. Immunol., 2005;116(1):65-72.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  379. Phenotype and function of myeloid dendritic cells derived from African green monkey blood monocytes.
    Authors: Mortara L, Ploquin MJ, Faye A, Scott-Algara D, Vaslin B, Butor C, Hosmalin A, Barre-Sinoussi F, Diop OM, Muller-Trutwin MC
    J. Immunol. Methods, 2005;308(1):138-55.
    Species: Primate - Chlorocebus pygerythrus (Vervet Monkey)
    Sample Type: Whole Cells
    Application: Bioassay
  380. CC chemokines and transmigration of eosinophils in the presence of vascular cell adhesion molecule 1.
    Authors: Yamamoto H, Nagata M, Sakamoto Y
    Ann. Allergy Asthma Immunol., 2005;94(2):292-300.
    Species: Human
    Sample Type: Cell Culture Supernates
    Application: Bioassay
  381. Phagocytosis of codeveloping megakaryocytic progenitors by dendritic cells in culture with thrombopoietin and tumor necrosis factor-alpha and its possible role in hemophagocytic syndrome.
    Authors: Saito K, Hirokawa M, Inaba K, Fukaya H, Kawabata Y, Komatsuda A, Yamashita J, Sawada K
    Blood, 2005;107(4):1366-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  382. TNFalpha increases the inflammatory response to vascular balloon injury without accelerating neointimal formation.
    Authors: Miller AM, McPhaden AR, Preston A, Wadsworth RM, Wainwright CL
    Atherosclerosis, 2005;179(1):51-9.
    Species: Rabbit
    Sample Type: Whole Cells
    Application: Bioassay
  383. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004;200(11):1419-26.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  384. Direct comparison of traditional ELISAs and membrane protein arrays for detection and quantification of human cytokines.
    Authors: Copeland S, Siddiqui J, Remick D
    J. Immunol. Methods, 2004;284(1):99-106.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  385. trans fatty acids and systemic inflammation in heart failure.
    Authors: Mozaffarian D, Rimm EB, King IB, Lawler RL, McDonald GB, Levy WC
    Am. J. Clin. Nutr., 2004;80(6):1521-5.
    Species: N/A
    Sample Type: N/A
    Application: ELISA Standard
  386. Impact of fibronectin fragments on the transendothelial migration of HIV-infected leukocytes and the development of subendothelial foci of infectious leukocytes.
    Authors: Birdsall HH, Porter WJ, Green DM, Rubio J, Trial J, Rossen RD
    J. Immunol., 2004;173(4):2746-54.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  387. TNF-related apoptosis-inducing ligand mediates human neuronal apoptosis: links to HIV-1-associated dementia.
    Authors: Ryan LA, Peng H, Erichsen DA, Huang Y, Persidsky Y, Zhou Y, Gendelman HE, Zheng J
    J. Neuroimmunol., 2004;148(1):127-39.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  388. Human bronchial epithelial cells express and secrete MMP-12.
    Authors: Lavigne MC, Thakker P, Gunn J, Miyashiro JS, Wasserman AM, Wei SQ, Pelker JW
    Biochem. Biophys. Res. Commun., 2004;324(2):534-46.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  389. Activation of primary porcine endothelial cells induces release of porcine endogenous retroviruses.
    Authors: Cunningham DA, Dos Santos Cruz GJ, Fernandez-Suarez XM, Whittam AJ, Herring C, Copeman L, Richards A, Langford GA
    Transplantation, 2004;77(7):1071-9.
    Species: Porcine
    Sample Type: Whole Cells
    Application: Bioassay
  390. Angiopoietin 1 and vascular endothelial growth factor modulate human glomerular endothelial cell barrier properties.
    Authors: Satchell SC, Anderson KL, Mathieson PW
    J. Am. Soc. Nephrol., 2004;15(3):566-74.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  391. Rapid chemokine secretion from endothelial cells originates from 2 distinct compartments.
    Authors: Oynebraten I, Bakke O, Brandtzaeg P, Johansen FE, Haraldsen G
    Blood, 2004;104(2):314-20.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  392. Eosinophils adhere to vascular cell adhesion molecule-1 via podosomes.
    Authors: Johansson MW, Lye MH, Barthel SR, Duffy AK, Annis DS, Mosher DF
    Am. J. Respir. Cell Mol. Biol., 2004;31(4):413-22.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  393. TARC augments TNF-alpha-induced CTACK production in keratinocytes.
    Authors: Vestergaard C, Johansen C, Christensen U, Just H, Hohwy T, Deleuran M
    Exp. Dermatol., 2004;13(9):551-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  394. KLF2 Is a novel transcriptional regulator of endothelial proinflammatory activation.
    Authors: SenBanerjee S, Lin Z, Atkins GB, Greif DM, Rao RM, Kumar A, Feinberg MW, Chen Z, Simon DI, Luscinskas FW, Michel TM, Gimbrone MA, Garcia-Cardena G, Jain MK
    J. Exp. Med., 2004;199(10):1305-15.
    Species: Bovine
    Sample Type: Whole Cells
    Application: Bioassay
  395. A soluble form of the triggering receptor expressed on myeloid cells-1 modulates the inflammatory response in murine sepsis.
    Authors: Gibot S, Kolopp-Sarda MN, Bollaert PE, Lozniewski A, Mory F, Levy B, Faure GC
    J. Exp. Med., 2004;200(11):1419-26.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  396. CC chemokine ligand 18, an atopic dermatitis-associated and dendritic cell-derived chemokine, is regulated by staphylococcal products and allergen exposure.
    Authors: Pivarcsi A, Gombert M, Dieu-Nosjean MC, Kubitza R, Meller S, Rieker J, Muller A, Da Cunha L, Haahtela A, Sonkoly E, Fridman WH, Alenius H, Kemeny L, Ruzicka T, Zlotnik A
    J. Immunol., 2004;173(9):5810-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  397. Rapid analysis of inflammatory cytokines in cerebrospinal fluid using chip-based immunoaffinity electrophoresis.
    Authors: Phillips TM
    Electrophoresis, 2004;25(10):1652-9.
    Species: N/A
    Sample Type: N/A
    Application: Standard
  398. Aberration of CCR7 CD8 memory T cells from patients with systemic lupus erythematosus: an inducer of T helper type 2 bias of CD4 T cells.
    Authors: Sen Y, Chunsong H, Baojun H, Linjie Z, Qun L, San J, Qiuping Z, Junyan L, Zhang X, Jinquan T
    Immunology, 2004;112(2):274-89.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  399. CD14 is an acute-phase protein.
    Authors: Bas S, Gauthier BR, Spenato U, Stingelin S, Gabay C
    J. Immunol., 2004;172(7):4470-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  400. IL-17 markedly up-regulates beta-defensin-2 expression in human airway epithelium via JAK and NF-kappaB signaling pathways.
    Authors: Kao CY, Chen Y, Thai P, Wachi S, Huang F, Kim C, Harper RW, Wu R
    J. Immunol., 2004;173(5):3482-91.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  401. The anti-apoptotic effect of Notch-1 requires p56lck-dependent, Akt/PKB-mediated signaling in T cells.
    Authors: Sade H, Krishna S, Sarin A
    J. Biol. Chem., 2004;279(4):2937-44.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  402. Distinct roles of IL-12 and IL-15 in human natural killer cell activation by dendritic cells from secondary lymphoid organs.
    Authors: Ferlazzo G, Pack M, Thomas D, Paludan C, Schmid D, Strowig T, Bougras G, Muller WA, Moretta L, Munz C
    Proc. Natl. Acad. Sci. U.S.A., 2004;101(47):16606-11.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  403. Synergistic induction of apoptosis in breast cancer cells by cotreatment with butyrate and TNF-alpha, TRAIL, or anti-Fas agonist antibody involves enhancement of death receptors' signaling and requires P21(waf1).
    Authors: Chopin V, Slomianny C, Hondermarck H, Le Bourhis X
    Exp. Cell Res., 2004;298(2):560-73.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  404. Induction of lysosomal and plasma membrane-bound sialidases in human T-cells via T-cell receptor.
    Authors: Wang P, Zhang J, Bian H, Wu P, Kuvelkar R, Kung TT, Crawley Y, Egan RW, Billah MM
    Biochem. J., 2004;380(0):425-33.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  405. The effect of inflammatory cytokines on secretion of macrophage colony-stimulating factor and monocyte chemoattractant protein-1 in human granulosa cells.
    Authors: Kawano Y, Fukuda J, Itoh H, Takai N, Nasu K, Miyakawa I
    Am. J. Reprod. Immunol., 2004;52(2):124-8.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  406. CXCR4 enhances adhesion of B16 tumor cells to endothelial cells in vitro and in vivo via beta(1) integrin.
    Authors: Cardones AR, Murakami T, Hwang ST
    Cancer Res., 2003;63(20):6751-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  407. Interleukin-8 production in tuberculous pleurisy: role of mesothelial cells stimulated by cytokine network involving tumour necrosis factor-alpha and interleukin-1 beta.
    Authors: Park JS, Kim YS, Jee YK, Myong NH, Lee KY
    Scand. J. Immunol., 2003;57(5):463-9.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  408. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
    Authors: McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N
    J. Clin. Invest., 2003;112(4):598-607.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  409. Stimulation of T cell autoreactivity by anomalous expression of NKG2D and its MIC ligands in rheumatoid arthritis.
    Authors: Groh V, Bruhl A, El-Gabalawy H, Nelson JL, Spies T
    Proc. Natl. Acad. Sci. U.S.A., 2003;100(16):9452-7.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  410. Endogenously expressed nef uncouples cytokine and chemokine production from membrane phenotypic maturation in dendritic cells.
    Authors: Messmer D, Jacque JM, Santisteban C, Bristow C, Han SY, Villamide-Herrera L, Mehlhop E, Marx PA, Steinman RM, Gettie A, Pope M
    J. Immunol., 2002;169(8):4172-82.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  411. Activation of NF-kappaB and upregulation of intracellular anti-apoptotic proteins via the IGF-1/Akt signaling in human multiple myeloma cells: therapeutic implications.
    Authors: Mitsiades CS, Mitsiades N, Poulaki V, Schlossman R, Akiyama M, Chauhan D, Hideshima T, Treon SP, Munshi NC, Richardson PG, Anderson KC
    Oncogene, 2002;21(37):5673-83.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  412. Acute topical application of tumor necrosis factor alpha evokes protein kinase A-dependent responses in rat sensory neurons.
    Authors: Zhang JM, Li H, Liu B, Brull SJ
    J. Neurophysiol., 2002;88(3):1387-92.
    Species: Rat
    Sample Type: In Vivo
    Application: In Vivo
  413. The correlation of adhesions and peritoneal fluid cytokine concentrations: a pilot study.
    Authors: Cheong YC, Laird SM, Shelton JB, Ledger WL, Li TC, Cooke ID
    Hum. Reprod., 2002;17(4):1039-45.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  414. LIGHT, a member of the tumor necrosis factor ligand superfamily, prevents tumor necrosis factor-alpha-mediated human primary hepatocyte apoptosis, but not Fas-mediated apoptosis.
    Authors: Hikichi Y, Tsuji I, Shintani Y
    J. Biol. Chem., 2002;277(51):50054-61.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  415. Lack of an immune response against the tetracycline-dependent transactivator correlates with long-term doxycycline-regulated transgene expression in nonhuman primates after intramuscular injection of recombinant adeno-associated virus.
    Authors: Favre D, Blouin V, Provost N, Spisek R, Porrot F, Bohl D, Marme F, Cherel Y, Salvetti A, Hurtrel B, Heard JM, Riviere Y, Moullier P
    J. Virol., 2002;76(22):11605-11.
    Species: Primate - Macaca fascicularis (Crab-eating Monkey or Cynomolgus Macaque)
    Sample Type: Whole Cells
    Application: Bioassay
  416. A cytokine-to-chemokine axis between T lymphocytes and keratinocytes can favor Th1 cell accumulation in chronic inflammatory skin diseases.
    Authors: Albanesi C, Scarponi C, Sebastiani S, Cavani A, Federici M, Sozzani S, Girolomoni G
    J. Leukoc. Biol., 2001;70(4):617-23.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  417. Perfusion-contraction mismatch with coronary microvascular obstruction: role of inflammation.
    Authors: Dorge H, Neumann T, Behrends M, Skyschally A, Schulz R, Kasper C, Erbel R, Heusch G
    Am. J. Physiol. Heart Circ. Physiol., 2000;279(6):H2587-92.
    Species: Canine
    Sample Type: Whole Cells
    Application: Bioassay
  418. Tumour necrosis factor-alpha- and interleukin-1beta-stimulated cell proliferation through activation of mitogen-activated protein kinase in canine tracheal smooth muscle cells.
    Authors: Yang CM, Luo SF, Wang CC, Chiu CT, Chien CS, Lin CC, Hsiao LD
    Br. J. Pharmacol., 2000;130(4):891-9.
    Species: Canine
    Sample Type: Whole Cells
    Application: Bioassay
  419. Expression of Fas/CD95 and Bcl-2 by primitive hematopoietic progenitors freshly isolated from human fetal liver.
    Authors: Barcena A, Park SW, Banapour B, Muench MO, Mechetner E
    Blood, 1996;88(6):2013-25.
    Species: Human
    Sample Type:
    Application: Bioassay
  420. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
    Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
    J Biol Chem, 0;284(36):24035-48.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
  421. Natural killer cell-produced IFN-gamma and TNF-alpha induce target cell cytolysis through up-regulation of ICAM-1.
    Authors: Wang R, Jaw JJ, Jaw J, Stutzman N, Stutzman NC, Zou Z, Sun PD
    J Leukoc Biol, 0;91(2):299-309.
    Species: Human
    Sample Type: Whole Cells
    Application: Bioassay
Expand to show all 421 Citations
Animal-Free Recombinant Proteins
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Recombinant Human TNF-alpha, Animal-Free Protein

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Average Rating: 4.9 (Based on 16 reviews)

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We have 15 reviews tested in 7 applications: In vivo study, In vitro bioactivity in cell culture, Cell migration/motility, Immunoassay Standard, Our lab has repeatedly purchased this product from 2014 until now. I could say it is excellent. And we will keep use it., Cell Adhesion, use TNF-alpha to stimulate human epithelial cell, the production of inflammation factor is stable and strongly evaluated by western blot and ELISA. .
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Our lab has repeatedly purchased this product from 2014 until now. I could say it is excellent. And we will keep use it.
(1)
Cell Adhesion
(2)
use TNF-alpha to stimulate human epithelial cell, the production of inflammation factor is stable and strongly evaluated by western blot and ELISA.
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  Excellent
 In vivo study Anonymous 10/30/2017
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Summary

ApplicationIn vivo study
In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA-020
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Excellent
 In vitro bioactivity in cell culture Anonymous 07/17/2017
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In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA-020
In vitro bioactivity in cell culture: Recombinant Human TNF-alpha Protein [210-TA-020]

Summary

ApplicationIn vitro bioactivity in cell culture
  Excellent
 In vitro bioactivity in cell culture Anonymous 06/01/2017
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Summary

ApplicationIn vitro bioactivity in cell culture
  Excellent
 Cell migration/motility Anonymous 05/23/2017
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Summary

ApplicationCell migration/motility
  Excellent
 In vitro bioactivity in cell culture Anonymous 05/16/2017
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Summary

ApplicationIn vitro bioactivity in cell culture
Reason for RatingConsistent and expect bioactive in our cell culture assays

Other Experimental Details

Other Experimental DetailsWe used TNF-a to stimulation macrophages and myofibroblast
  Excellent
  Anonymous 05/15/2017
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  Excellent
 In vitro bioactivity in cell culture Anonymous 12/19/2016
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Summary

ApplicationIn vitro bioactivity in cell culture
Reason for RatingFunctioned well and reproducible data with TNF from another company.
In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA
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Very Good
 In vitro bioactivity in cell culture Anonymous 08/01/2016
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In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA
In vitro bioactivity in cell culture: Recombinant Human TNF-alpha Protein [210-TA]

Summary

ApplicationIn vitro bioactivity in cell culture

Other Experimental Details

Other Experimental DetailsRat primary embryonic cortical culture stimulated with TNFa (10, 50, 100 ng/ml), PBS+BSA (negative stimulation control), or Okadaic Acid (OA; positive phosphorylation control) for 30 minutes. Protein isolated for western blot analysis of phospho-Akt.
In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA
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Excellent
 In vitro bioactivity in cell culture Anonymous 07/29/2016
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In vitro bioactivity in cell culture Recombinant Human TNF-alpha Protein 210-TA
In vitro bioactivity in cell culture: Recombinant Human TNF-alpha Protein [210-TA]

Summary

ApplicationIn vitro bioactivity in cell culture

Other Experimental Details

Other Experimental DetailsCultured endothelial cells were pre-treated (or not) with 1mg/mL HDL, then treated for 6 hours with 10ng/mL TNFa. TNFa treatment caused a massive upregulation of ICAM1 and E-Selectin versus control cells (untreated); HDL pre-treatment partially reversed this response.
  Excellent
 In vitro bioactivity in cell culture Anonymous 07/21/2016
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Summary

ApplicationIn vitro bioactivity in cell culture
  Excellent
 In vitro bioactivity in cell culture Anonymous 07/21/2016
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Summary

ApplicationIn vitro bioactivity in cell culture
Reason for RatingAt equal concentrations this protein supplied by R and D systems showed biological activity in our assay system (induction of known downstream genes) when the same protein from two other suppliers failed in all but the positive control condition.
  Very Good
 Immunoassay Standard Anonymous 05/16/2016
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Summary

ApplicationImmunoassay Standard
Our lab has repeatedly purchased this product from 2014 until now. I could say it is excellent. And we will keep use it. Recombinant Human TNF-alpha Protein 210-TA
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Excellent
 Our lab has repeatedly purchased this product from 2014 until now. I could say it is excellent. And we will keep use it. Anonymous 05/12/2016
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Our lab has repeatedly purchased this product from 2014 until now. I could say it is excellent. And we will keep use it. Recombinant Human TNF-alpha Protein 210-TA
Our lab has repeatedly purchased this product from 2014 until now. I could say it is excellent. And we will keep use it.: Recombinant Human TNF-alpha Protein [210-TA]

Summary

ApplicationOur lab has repeatedly purchased this product from 2014 until now. I could say it is excellent. And we will keep use it.
Cell Adhesion Recombinant Human TNF-alpha Protein 210-TA
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Excellent
 Cell Adhesion Anonymous 02/12/2016
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Cell Adhesion Recombinant Human TNF-alpha Protein 210-TA
Cell Adhesion: Recombinant Human TNF-alpha Protein [210-TA]

Summary

ApplicationCell Adhesion
Reason for RatingThis has worked well in WB
Cell Adhesion Recombinant Human TNF-alpha Protein 210-TA
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Excellent
 Cell Adhesion Anonymous 01/29/2016
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Cell Adhesion Recombinant Human TNF-alpha Protein 210-TA
Cell Adhesion: Recombinant Human TNF-alpha Protein [210-TA]

Summary

ApplicationCell Adhesion
Reason for Ratingthe band is strong and clear.
  Excellent
 use TNF-alpha to stimulate human epithelial cell, the production of inflammation factor is stable and strongly evaluated by western blot and ELISA. Anonymous 01/13/2016
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Summary

Applicationuse TNF-alpha to stimulate human epithelial cell, the production of inflammation factor is stable and strongly evaluated by western blot and ELISA.
Reason for Ratingstable cheap and convenience

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