Recombinant Mouse M-CSF Protein

Formulations:
Catalog # Availability Size / Price Qty
416-ML-010
416-ML-050
416-ML-500
Graph showing dose-dependent bioactivity of Human M-CSF Protein
1 Image
Product Details
Citations (336)
FAQs
Supplemental Products
Reviews (14)

Recombinant Mouse M-CSF Protein Summary

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<1.0 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cell proliferation assay using M‑NFS‑60 mouse myelogenous leukemia lymphoblast cells. Nakoinz, I. et al. (1990) J. Immunol. 145:860. The ED50 for this effect is 0.5‑3 ng/mL.
Source
E. coli-derived mouse M-CSF protein
Lys33-Glu262, with an N-terminal Met
Accession #
N-terminal Sequence
Analysis
Met
Structure / Form
Disulfide-linked homodimer
Predicted Molecular Mass
26 kDa (monomer)
SDS-PAGE
29 kDa, reducing conditions

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

416-ML

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

416-ML/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

Data Image

Bioactivity Bioactivity of M-CSF Protein View Larger

Recombinant Mouse M-CSF (416-ML) stimulates cell proliferation in the M-NFS-60 mouse myelogenous leukemia lymphoblast cell line in a dose-dependent manner. The ED50 for this effect is 0.5-3 ng/mL.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: M-CSF

M-CSF, also known as CSF-1, is a four-alpha -helical-bundle cytokine that is the primary regulator of macrophage survival, proliferation and differentiation (1-3). M-CSF protein is also essential for the survival and proliferation of osteoclast progenitors (1, 4). M-CSF also primes and enhances macrophage killing of tumor cells and microorganisms, regulates the release of cytokines and other inflammatory modulators from macrophages, and stimulates pinocytosis (2, 3). M-CSF increases during pregnancy to support implantation and growth of the decidua and placenta (5). Sources of M-CSF include fibroblasts, activated macrophages, endometrial secretory epithelium, bone marrow stromal cells and activated endothelial cells (1-5). The M-CSF receptor (c-fms) transduces its pleotropic effects and mediates its endocytosis. M-CSF mRNAs of various sizes occur (3-9). Full length mouse M-CSF transcripts encode a 520 amino acid (aa) type I transmembrane (TM) protein with a 462 aa extracellular region, a 21 aa TM domain, and a 37 aa cytoplasmic tail that forms a 140 kDa covalent dimer. Differential processing produces two proteolytically cleaved, secreted dimers. One is an N- and O- glycosylated 86 kDa dimer, while the other is modified by both glycosylation and chondroitin-sulfate proteoglycan (PG) to generate a 200 kDa subunit. Although PG-modified M-CSF protein can circulate, it may be immobilized by attachment to type V collagen (8). Shorter transcripts encode M‑CSF that lacks cleavage and PG sites and produces an N-glycosylated 68 kDa TM dimer and a slowly produced 44 kDa secreted dimer (7). Although forms may vary in activity and half-life, all contain the N-terminal 150 aa portion that is necessary and sufficient for interaction with the M-CSF receptor (10, 11). The first 229 aa of mature mouse M-CSF shares 87%, 83%, 82% and 81% aa identity with corresponding regions of rat, dog, cow and human M-CSF, respectively (12, 13). Human M‑CSF is active in the mouse, but mouse M-CSF is reported to be species-specific.

References
  1. Pixley, F.J. and E.R. Stanley (2004) Trends Cell Biol. 14:628.
  2. Chitu, V. and E.R. Stanley (2006) Curr. Opin. Immunol. 18:39.
  3. Fixe, P. and V. Praloran (1997) Eur. Cytokine Netw. 8:125.
  4. Ryan, G.R. et al. (2001) Blood 98:74.
  5. Makrigiannakis, A. et al. (2006) Trends Endocrinol. Metab. 17:178.
  6. Nandi, S. et al. (2006) Blood 107:786.
  7. Rettenmier, C.W. and M.F. Roussel (1988) Mol. Cell Biol. 8:5026.
  8. Suzu, S. et al. (1992) J. Biol. Chem. 267:16812.
  9. Manos, M.M. (1988) Mol. Cell. Biol. 8:5035.
  10. Koths, K. (1997) Mol. Reprod. Dev. 46:31.
  11. Jang, M-H. et al. (2006) J. Immunol. 177:4055.
  12. DeLamarter, J.F. et al. (1987) Nucleic Acids Res. 15:2389.
  13. Ladner, M.B. et al. (1988) Proc. Natl. Acad. Sci. USA 85:6706.
Long Name
Macrophage Colony Stimulating Factor
Entrez Gene IDs
1435 (Human); 12977 (Mouse)
Alternate Names
colony stimulating factor 1 (macrophage); CSF1; CSF-1; Lanimostim; macrophage colony stimulating factor; macrophage colony-stimulating factor 1; MCSF; M-CSF; MCSFlanimostim; MGC31930

Citations for Recombinant Mouse M-CSF Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

336 Citations: Showing 1 - 10
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  1. A RUNX2 stabilization pathway mediates physiologic and pathologic bone formation
    Authors: JM Kim, YS Yang, KH Park, X Ge, R Xu, N Li, M Song, H Chun, S Bok, JF Charles, O Filhol-Coc, B Boldyreff, T Dinter, PB Yu, N Kon, W Gu, T Takarada, MB Greenblatt, JH Shim
    Nat Commun, 2020;11(1):2289.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. CNTF-STAT3-IL-6 Axis Mediates Neuroinflammatory Cascade across Schwann Cell-Neuron-Microglia
    Authors: Z Hu, N Deng, K Liu, N Zhou, Y Sun, W Zeng
    Cell Rep, 2020;31(7):107657.
    Species: Mouse
    Sample Types:
    Applications: In Vivo
  3. Hedgehog Inhibitors Suppress Osteoclastogenesis in In Vitro Cultures, and Deletion of Smo in Macrophage/Osteoclast Lineage Prevents Age-Related Bone Loss
    Authors: Y Kohara, R Haraguchi, R Kitazawa, Y Imai, S Kitazawa
    Int J Mol Sci, 2020;21(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  4. Distinct iron homeostasis in C57BL/6 and Balb/c mouse strains
    Authors: P Saha, X Xiao, Y Li, RM Golonka, AA Abokor, BS Yeoh, M Vijay-Kuma
    Physiol Rep, 2020;8(9):e14441.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Microglia response following acute demyelination is heterogeneous and limits infiltrating macrophage dispersion
    Authors: JR Plemel, JA Stratton, NJ Michaels, KS Rawji, E Zhang, S Sinha, CS Baaklini, Y Dong, M Ho, K Thorburn, TN Friedman, S Jawad, C Silva, AV Caprariell, V Hoghooghi, J Yue, A Jaffer, K Lee, BJ Kerr, R Midha, PK Stys, J Biernaskie, VW Yong
    Sci Adv, 2020;6(3):eaay6324.
    Species: Mouse
    Sample Types: Cell Culture Supernates
    Applications: Cell Culture
  6. Environmental arginine controls multinuclear giant cell metabolism and formation
    Authors: JS Brunner, L Vulliard, M Hofmann, M Kieler, A Lercher, A Vogel, M Russier, JB Brüggenthi, M Kerndl, V Saferding, B Niederreit, A Junza, A Frauenstei, C Scholtysek, Y Mikami, K Klavins, G Krönke, A Bergthaler, JJ O'Shea, T Weichhart, F Meissner, JS Smolen, P Cheng, O Yanes, J Menche, PJ Murray, O Sharif, S Blüml, G Schabbauer
    Nat Commun, 2020;11(1):431.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  7. PI3K activation increases SDF-1 production and number of osteoclast precursors, and enhances SDF-1-mediated osteoclast precursor migration
    Authors: NS Adapala, S Root, J Lorenzo, H Aguila, A Sanjay
    Bone Rep, 2019;10(0):100203.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. The Parkinson's disease-linked Leucine-rich repeat kinase 2 (LRRK2) is required for insulin-stimulated translocation of GLUT4
    Authors: N Funk, M Munz, T Ott, K Brockmann, A Wenninger-, R Kühn, D Vogt-Weise, F Giesert, W Wurst, T Gasser, S Biskup
    Sci Rep, 2019;9(1):4515.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Mycobacterium tuberculosis Rv3463 induces mycobactericidal activity in macrophages by enhancing phagolysosomal fusion and exhibits therapeutic potential
    Authors: HS Park, YW Back, KW Shin, HS Bae, KI Lee, HG Choi, S Choi, HH Lee, CH Choi, JK Park, HJ Kim
    Sci Rep, 2019;9(1):4246.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Siglec-15 as an immune suppressor and potential target for normalization cancer immunotherapy
    Authors: J Wang, J Sun, LN Liu, DB Flies, X Nie, M Toki, J Zhang, C Song, M Zarr, X Zhou, X Han, KA Archer, T O'Neill, RS Herbst, AN Boto, MF Sanmamed, S Langermann, DL Rimm, L Chen
    Nat. Med., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Enhancement of the gut barrier integrity by a microbial metabolite through the Nrf2 pathway
    Authors: R Singh, S Chandrashe, SR Bodduluri, BV Baby, B Hegde, NG Kotla, AA Hiwale, T Saiyed, P Patel, M Vijay-Kuma, MGI Langille, GM Douglas, X Cheng, EC Rouchka, SJ Waigel, GW Dryden, H Alatassi, HG Zhang, B Haribabu, PK Vemula, VR Jala
    Nat Commun, 2019;10(1):89.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. Global deletion of Optineurin results in altered type I IFN signaling and abnormal bone remodeling in a model of Paget's disease
    Authors: SW Wong, BW Huang, X Hu, E Ho Kim, JP Kolb, RJ Padilla, P Xue, L Wang, TH Oguin, PA Miguez, HC Tseng, CC Ko, J Martinez
    Cell Death Differ., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. A cell-penetrating peptide blocks Toll-like receptor-mediated downstream signaling and ameliorates autoimmune and inflammatory diseases in mice
    Authors: HK Kwon, MC Patra, HJ Shin, X Gui, A Achek, S Panneersel, DJ Kim, SJ Song, R Hong, KS Kim, YG Kim, FY Lee, DH Hahm, SH Lee, S Choi
    Exp. Mol. Med., 2019;51(4):50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  14. MyD88 and IL-1R signaling drive antibacterial immunity and osteoclast-driven bone loss during Staphylococcus aureus osteomyelitis
    Authors: NE Putnam, LE Fulbright, JM Curry, CA Ford, JR Petronglo, AS Hendrix, JE Cassat
    PLoS Pathog., 2019;15(4):e1007744.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Tumor derived EDIL3 modulates the expansion and osteoclastogenesis of myeloid derived suppressor cells in murine breast cancer model
    Authors: Z Kun, G Xin, W Tao, Z Chenglong, W Dongsheng, T Liang, L Tielong, X Jianru
    J Bone Oncol, 2019;16(0):100238.
    Species: Mouse
    Sample Types: Tumor Cells
    Applications: Bioassay
  16. Rg6, a rare ginsenoside, inhibits systemic inflammation through the induction of interleukin-10 and microRNA-146a
    Authors: S Paik, JH Choe, GE Choi, JE Kim, JM Kim, GY Song, EK Jo
    Sci Rep, 2019;9(1):4342.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  17. Exosomal miRNA-19b-3p of tubular epithelial cells promotes M1 macrophage activation in kidney injury
    Authors: LL Lv, Y Feng, M Wu, B Wang, ZL Li, X Zhong, WJ Wu, J Chen, HF Ni, TT Tang, RN Tang, HY Lan, BC Liu
    Cell Death Differ., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  18. Cathepsin K-deficient osteocytes prevent lactation-induced bone loss and parathyroid hormone suppression
    Authors: S Lotinun, Y Ishihara, K Nagano, R Kiviranta, V Carpentier, L Neff, V Parkman, N Ide, D Hu, P Dann, D Brooks, ML Bouxsein, J Wysolmersk, F Gori, R Baron
    J. Clin. Invest., 2019;130(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  19. Characterisation of genes differentially expressed in macrophages by virulent and attenuated Mycobacterium tuberculosis through RNA-Seq analysis
    Authors: J Lee, SG Lee, KK Kim, YJ Lim, JA Choi, SN Cho, C Park, CH Song
    Sci Rep, 2019;9(1):4027.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. SIRT3 promotes antimycobacterial defenses by coordinating mitochondrial and autophagic functions
    Authors: TS Kim, YB Jin, YS Kim, S Kim, JK Kim, HM Lee, HW Suh, JH Choe, YJ Kim, BS Koo, HN Kim, M Jung, SH Lee, DK Kim, C Chung, JW Son, JJ Min, JM Kim, CX Deng, HS Kim, SR Lee, EK Jo
    Autophagy, 2019;0(0):20-Jan.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  21. Iron alters macrophage polarization status and leads to steatohepatitis and fibrogenesis
    Authors: P Handa, S Thomas, V Morgan-Ste, BD Maliken, E Gochanour, S Boukhar, MM Yeh, KV Kowdley
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Regulation of cytoskeleton and adhesion signaling in osteoclasts by tetraspanin CD82
    Authors: A Bergsma, SS Ganguly, ME Wiegand, D Dick, BO Williams, CK Miranti
    Bone Rep, 2019;10(0):100196.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. Stachydrine prevents LPS-induced bone loss by inhibiting osteoclastogenesis via NF-κB and Akt signalling
    Authors: J Meng, C Zhou, W Zhang, W Wang, B He, B Hu, G Jiang, Y Wang, J Hong, S Li, J He, S Yan, W Yan
    J. Cell. Mol. Med., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  24. Evodiamine inhibits RANKL-induced osteoclastogenesis and prevents ovariectomy-induced bone loss in mice
    Authors: H Jin, L Yao, K Chen, Y Liu, Q Wang, Z Wang, Q Liu, Z Cao, J Kenny, J Tickner, X Wang, J Xu
    J. Cell. Mol. Med., 2019;23(1):522-534.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. A potential therapeutic target for regulating osteoporosis via suppression of osteoclast differentiation
    Authors: Q Sun, B Zhang, W Zhu, W Wei, J Ma, FR Tay
    J Dent, 2019;0(0):.
    Species: Mouse
    Sample Types:
    Applications: Bioassay
  26. Fasciola hepatica GST downregulates NF-?B pathway effectors and inflammatory cytokines while promoting survival in a mouse septic shock model
    Authors: V Aguayo, BN Valdés Fer, M Rodríguez-, C Ruiz-Jimén, MJ Ramos-Bení, LB Méndez, AM Espino
    Sci Rep, 2019;9(1):2275.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. CD200 Modulates S. aureus-Induced Innate Immune Responses Through Suppressing p38 Signaling
    Authors: B Zhu, Y Yu, X Liu, Q Han, Y Kang, L Shi
    Int J Mol Sci, 2019;20(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Dampened NLRP3-mediated inflammation in bats and implications for a special viral reservoir host
    Authors: M Ahn, DE Anderson, Q Zhang, CW Tan, BL Lim, K Luko, M Wen, WN Chia, S Mani, LC Wang, JHJ Ng, RM Sobota, CA Dutertre, F Ginhoux, ZL Shi, AT Irving, LF Wang
    Nat Microbiol, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  29. Oxidized LDL upregulates macrophage DPP4 expression via TLR4/TRIF/CD36 pathways
    Authors: X Rao, S Zhao, Z Braunstein, H Mao, M Razavi, L Duan, Y Wei, AC Toomey, S Rajagopala, J Zhong
    EBioMedicine, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  30. The neurosteroid, pregnenolone promotes degradation of key proteins in the innate immune signalling to suppress inflammation
    Authors: S Murugan, P Jakka, S Namani, V Mujumdar, G Radhakrish
    J. Biol. Chem., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. Skeletal phenotype of the neuropeptide Y knockout mouse
    Authors: NKY Wee, BP Sinder, S Novak, X Wang, C Stoddard, BG Matthews, I Kalajzic
    Neuropeptides, 2019;73(0):78-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  32. L-caldesmon alters cell spreading and adhesion force in RANKL-induced osteoclasts
    Authors: CL Chan, JY Chen, MC Shih, CA Wang, YM Liou
    J. Biomed. Sci., 2019;26(1):12.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Long noncoding RNA Malat1 regulates differential activation of macrophage and response to lung injury
    Authors: H Cui, S Banerjee, S Guo, N Xie, J Ge, D Jiang, M Zörnig, VJ Thannickal, G Liu
    JCI Insight, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  34. Caspase-1 initiates apoptosis in the absence of gasdermin D
    Authors: K Tsuchiya, S Nakajima, S Hosojima, D Thi Nguyen, T Hattori, T Manh Le, O Hori, MR Mahib, Y Yamaguchi, M Miura, T Kinoshita, H Kushiyama, M Sakurai, T Shiroishi, T Suda
    Nat Commun, 2019;10(1):2091.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  35. Discovery of new inhibitors against both NF-?B and osteoclastogenesis from in-house library with ?, ?-unsaturated-enone fragment
    Authors: C Zhao, D Huang, R Li, J Xu, Q Gu, J Xu
    Bioorg. Chem., 2019;87(0):638-646.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  36. Nerve modulation therapy in gouty arthritis: targeting increased sFRP2 expression in dorsal root ganglion regulates macrophage polarization and alleviates endothelial damage
    Authors: J Mei, F Zhou, H Qiao, H Li, T Tang
    Theranostics, 2019;9(13):3707-3722.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  37. A Novel Sulforaphane-Regulated Gene Network in Suppression of Breast Cancer-Induced Osteolytic Bone Resorption
    Authors: SK Pore, ER Hahm, SH Kim, KB Singh, L Nyiranshut, JD Latoche, CJ Anderson, J Adamik, DL Galson, KR Weiss, RJ Watters, B Lee, PN Kumta, SV Singh
    Mol. Cancer Ther., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. PRMT6 promotes lung tumor progression via the alternate activation of tumor-associated macrophages
    Authors: S Avasarala, PY Wu, SQ Khan, S Yanlin, M Van Scoyk, J Bao, A Di Lorenzo, O David, MT Bedford, V Gupta, RA Winn, RK Bikkavilli
    Mol. Cancer Res., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  39. MicroRNA-29a Counteracts Glucocorticoid Induction of Bone Loss through Repressing TNFSF13b Modulation of Osteoclastogenesis
    Authors: RW Wu, WS Lian, YS Chen, CW Kuo, HC Ke, CK Hsieh, SY Wang, JY Ko, FS Wang
    Int J Mol Sci, 2019;20(20):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Cell Culture
  40. The interferon stimulated gene 20 protein (ISG20) is an innate defense antiviral factor that discriminates self versus non-self translation
    Authors: N Wu, XN Nguyen, L Wang, R Appourchau, C Zhang, B Panthu, H Gruffat, C Journo, S Alais, J Qin, N Zhang, K Tartour, F Catez, R Mahieux, T Ohlmann, M Liu, B Du, A Cimarelli
    PLoS Pathog., 2019;15(10):e1008093.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  41. Cleavage of RIPK1 by caspase-8�is crucial for limiting apoptosis and necroptosis
    Authors: K Newton, KE Wickliffe, DL Dugger, A Maltzman, M Roose-Girm, M Dohse, L K?m?ves, JD Webster, VM Dixit
    Nature, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. P2Y6 signaling in alveolar macrophages prevents leukotriene-dependent type 2 allergic lung inflammation
    Authors: J Nagai, B Balestrier, LB Fanning, T Kyin, H Cirka, J Lin, M Idzko, A Zech, EY Kim, PJ Brennan, JA Boyce
    J. Clin. Invest., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Inhibitory effects of dabigatran etexilate, a direct thrombin inhibitor, on osteoclasts and osteoblasts
    Authors: AL Rocha, RL Bighetti-T, LF Duffles, JAA de Arruda, TM Taira, BRD Assis, S Macari, IMA Diniz, MM Beloti, AL Rosa, SY Fukada, GAC Goulart, DD Ribeiro, LG Abreu, TA Silva
    Thromb. Res., 2019;186(0):45-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  44. The protective effect of WKYMVm peptide on inflammatory osteolysis through regulating NF-kappaB and CD9/gp130/STAT3 signalling pathway
    Authors: J Hu, X Li, Y Chen, X Han, L Li, Z Yang, L Duan, H Lu, Q He
    J. Cell. Mol. Med., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  45. Adult stem cell deficits drive Slc29a3 disorders in mice
    Authors: S Nair, AM Strohecker, AK Persaud, B Bissa, S Muruganand, C McElroy, R Pathak, M Williams, R Raj, A Kaddoumi, A Sparreboom, AM Beedle, R Govindaraj
    Nat Commun, 2019;10(1):2943.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation
  46. Acidity promotes tumour progression by altering macrophage phenotype in prostate cancer
    Authors: A El-Kenawi, C Gatenbee, M Robertson-, R Bravo, J Dhillon, Y Balaguruna, A Berglund, N Visvakarma, A Ibrahim-Ha, J Choi, K Luddy, R Gatenby, S Pilon-Thom, A Anderson, B Ruffell, R Gillies
    Br. J. Cancer, 2019;121(7):556-566.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  47. Interleukin-27 Is Essential for Type 1 Diabetes Development and Sj�gren Syndrome-like Inflammation
    Authors: AE Ciecko, B Foda, JY Barr, S Ramanathan, MA Atkinson, DV Serreze, AM Geurts, SM Lieberman, YG Chen
    Cell Rep, 2019;29(10):3073-3086.e5.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Tissue Culture
  48. Diterpenoids from the aerial parts of Flueggea acicularis and their activity against RANKL-induced osteoclastogenesis
    Authors: D Huang, X Luo, Z Yin, J Xu, Q Gu
    Bioorg. Chem., 2019;0(0):103453.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Phillyrin Attenuates Osteoclast Formation and Function and Prevents LPS-Induced Osteolysis in Mice
    Authors: J Wang, G Chen, Q Zhang, F Zhao, X Yu, X Ma, M Liu
    Front Pharmacol, 2019;10(0):1188.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. Lycorine Attenuates Autophagy in Osteoclasts via an Axis of mROS/TRPML1/TFEB to Reduce LPS-Induced Bone Loss
    Authors: HJ Park, M Gholam-Zad, JH Suh, HS Choi
    Oxid Med Cell Longev, 2019;2019(0):8982147.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  51. Mitofusin 2-Deficiency Suppresses Mycobacterium tuberculosis Survival in Macrophages
    Authors: J Lee, JA Choi, SN Cho, SH Son, CH Song
    Cells, 2019;8(11):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  52. Nobiletin-loaded micelles reduce ovariectomy-induced bone loss by suppressing osteoclastogenesis
    Authors: Y Wang, J Xie, Z Ai, J Su
    Int J Nanomedicine, 2019;14(0):7839-7849.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  53. Gas6/MerTK signaling is negatively regulated by NF-&kappaB and supports lung carcinogenesis
    Authors: SV Novitskiy, R Zaynagetdi, G Vasiukov, S Gutor, W Han, A Serezani, A Matafonov, LA Gleaves, TP Sherrill, VV Polosukhin, TS Blackwell
    Oncotarget, 2019;10(66):7031-7042.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  54. The Nrf2 activator RTA-408 attenuates osteoclastogenesis by inhibiting STING dependent NF-?b signaling
    Authors: X Sun, Z Xie, B Hu, B Zhang, Y Ma, X Pan, H Huang, J Wang, X Zhao, Z Jie, P Shi, Z Chen
    Redox Biol, 2019;28(0):101309.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Bone-targeting AAV-mediated silencing of Schnurri-3 prevents bone loss in osteoporosis
    Authors: YS Yang, J Xie, D Wang, JM Kim, PWL Tai, E Gravallese, G Gao, JH Shim
    Nat Commun, 2019;10(1):2958.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  56. Propofol directly induces caspase-1-dependent macrophage pyroptosis through the NLRP3-ASC inflammasome
    Authors: L Sun, W Ma, W Gao, Y Xing, L Chen, Z Xia, Z Zhang, Z Dai
    Cell Death Dis, 2019;10(8):542.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  57. Salmonella Coiled-Coil- and TIR-Containing TcpS Evades the Innate Immune System and Subdues Inflammation
    Authors: D Xiong, L Song, S Geng, Y Jiao, X Zhou, H Song, X Kang, Y Zhou, X Xu, J Sun, Z Pan, X Jiao
    Cell Rep, 2019;28(3):804-818.e7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Cathepsin L secretion by host and neoplastic cells potentiates invasion
    Authors: SS Dykes, HO Fasanya, DW Siemann
    Oncotarget, 2019;10(53):5560-5568.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. MicroRNA-29a represses osteoclast formation and protects against osteoporosis by regulating PCAF-mediated RANKL and CXCL12
    Authors: WS Lian, JY Ko, YS Chen, HJ Ke, CK Hsieh, CW Kuo, SY Wang, BW Huang, JG Tseng, FS Wang
    Cell Death Dis, 2019;10(10):705.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  60. Statin as a novel pharmacotherapy of pulmonary alveolar proteinosis
    Authors: C McCarthy, E Lee, JP Bridges, A Sallese, T Suzuki, JC Woods, BJ Bartholmai, T Wang, C Chalk, BC Carey, P Arumugam, K Shima, EJ Tarling, BC Trapnell
    Nat Commun, 2018;9(1):3127.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Human umbilical cord-derived mesenchymal stem cells direct macrophage polarization to alleviate pancreatic islets dysfunction in type 2 diabetic mice
    Authors: Y Yin, H Hao, Y Cheng, L Zang, J Liu, J Gao, J Xue, Z Xie, Q Zhang, W Han, Y Mu
    Cell Death Dis, 2018;9(7):760.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  62. Coupling of bone resorption and formation by RANKL reverse signalling
    Authors: Y Ikebuchi, S Aoki, M Honma, M Hayashi, Y Sugamori, M Khan, Y Kariya, G Kato, Y Tabata, JM Penninger, N Udagawa, K Aoki, H Suzuki
    Nature, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. Modulating bone marrow hematopoietic lineage potential to prevent bone metastasis in breast cancer
    Authors: JM Ubellacker, N Baryawno, N Severe, MJ DeCristo, J Sceneay, JN Hutchinson, MT Haider, CS Rhee, Y Qin, WM Gregory, AC Garrido-Ca, I Holen, JE Brown, RE Coleman, DT Scadden, SS McAllister
    Cancer Res., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Silencing LAIR-1 in human THP-1 macrophage increases foam cell formation by modulating PPAR? and M2 polarization
    Authors: X Yi, J Zhang, R Zhuang, S Wang, S Cheng, D Zhang, J Xie, W Hu, X Liu, Y Zhang, Y Ding, Y Zhang
    Cytokine, 2018;111(0):194-205.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  65. Bone marrow mesenchymal stem cells tune the differentiation of myeloid-derived suppressor cells in bleomycin-induced lung injury
    Authors: X Su, L Yang, Y Yin, J Huang, F Qiao, Y Fang, L Yu, Y Wang, K Zhou, J Wang
    Stem Cell Res Ther, 2018;9(1):253.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. Glucosylceramide modifies the LPS-induced inflammatory response in macrophages and the orientation of the LPS/TLR4 complex in silico
    Authors: E Mobarak, L Håversen, M Manna, M Rutberg, M Levin, R Perkins, T Rog, I Vattulaine, J Borén
    Sci Rep, 2018;8(1):13600.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. GABAergic signaling linked to autophagy enhances host protection against intracellular bacterial infections
    Authors: JK Kim, YS Kim, HM Lee, HS Jin, C Neupane, S Kim, SH Lee, JJ Min, M Sasai, JH Jeong, SK Choe, JM Kim, M Yamamoto, HE Choy, JB Park, EK Jo
    Nat Commun, 2018;9(1):4184.
  68. Stevioside Prevents Wear Particle-Induced Osteolysis by Inhibiting Osteoclastogenesis and Inflammatory Response via the Suppression of TAK1 Activation
    Authors: J Meng, C Zhou, B Hu, M Luo, Y Yang, Y Wang, W Wang, G Jiang, J Hong, S Li, H Wu, S Yan, W Yan
    Front Pharmacol, 2018;9(0):1053.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  69. The Trem2 R47H Alzheimer's risk variant impairs splicing and reduces Trem2 mRNA and protein in mice but not in humans
    Authors: X Xiang, TM Piers, B Wefers, K Zhu, A Mallach, B Brunner, G Kleinberge, W Song, M Colonna, J Herms, W Wurst, JM Pocock, C Haass
    Mol Neurodegener, 2018;13(1):49.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. A dual-specific macrophage colony-stimulating factor antagonist of c-FMS and ?v?3 integrin for osteoporosis therapy
    Authors: Y Zur, L Rosenfeld, CA Keshelman, N Dalal, G Guterman-R, A Orenbuch, Y Einav, N Levaot, N Papo
    PLoS Biol., 2018;16(8):e2002979.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  71. Indian Hedgehog Suppresses a Stromal Cell-Driven Intestinal Immune Response
    Authors: BF Westendorp, NVJA Büller, ON Karpus, WA van Dop, J Koster, R Versteeg, PJ Koelink, CY Snel, S Meisner, JJTH Roelofs, A Uhmann, E Ver Loren, J Heijmans, H Hahn, V Muncan, ME Wildenberg, GR van den Br
    Cell Mol Gastroenterol Hepatol, 2018;5(1):67-82.e1.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Mononuclear phagocytes locally specify and adapt their phenotype in a multiple sclerosis model
    Authors: G Locatelli, D Theodorou, A Kendirli, MJC Jordão, O Staszewski, K Phulphagar, L Cantuti-Ca, A Dagkalis, A Bessis, M Simons, F Meissner, M Prinz, M Kerschenst
    Nat. Neurosci., 2018;21(9):1196-1208.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. In Silico Discovery of Plant-Origin Natural Product Inhibitors of Tumor Necrosis Factor (TNF) and Receptor Activator of NF-?B Ligand (RANKL)
    Authors: G Melagraki, E Ntougkos, D Papadopoul, V Rinotas, G Leonis, E Douni, A Afantitis, G Kollias
    Front Pharmacol, 2018;9(0):800.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. Effects of metal ions on caspase-1 activation and interleukin-1? release in murine bone marrow-derived macrophages
    Authors: MA Ferko, I Catelas
    PLoS ONE, 2018;13(8):e0199936.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Artemisinin-Daumone Hybrid Inhibits Cancer Cell-Mediated Osteolysis by Targeting Cancer Cells and Osteoclasts
    Authors: GT Ma, SK Lee, KK Park, J Park, SH Son, M Jung, WY Chung
    Cell. Physiol. Biochem., 2018;49(4):1460-1475.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Treatment of collagenase-induced osteoarthritis with a viral vector encoding TSG-6 results in ectopic bone formation
    Authors: MGA Broeren, I Di Ceglie, MB Bennink, PLEM van Lent, WB van den Be, MI Koenders, EN Blaney Dav, PM van der Kr, FAJ van de Loo
    PeerJ, 2018;6(0):e4771.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Inflammatory response of microglia to prions is controlled by sialylation of PrPSc
    Authors: S Srivastava, E Katorcha, N Makarava, JP Barrett, DJ Loane, IV Baskakov
    Sci Rep, 2018;8(1):11326.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. Reduced oxidative capacity in macrophages results in systemic insulin resistance
    Authors: SB Jung, MJ Choi, D Ryu, HS Yi, SE Lee, JY Chang, HK Chung, YK Kim, SG Kang, JH Lee, KS Kim, HJ Kim, CS Kim, CH Lee, RW Williams, H Kim, HK Lee, J Auwerx, M Shong
    Nat Commun, 2018;9(1):1551.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
    Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages
    Authors: Y Hu, F Song, H Jiang, G Nuñez, DE Smith
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. RGC32 Promotes Bleomycin-Induced Systemic Sclerosis in a Murine Disease Model by Modulating Classically Activated Macrophage Function
    Authors: C Sun, SY Chen
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  82. IFN Regulatory Factor 2 Inhibits Expression of Glycolytic Genes and Lipopolysaccharide-Induced Proinflammatory Responses in Macrophages
    Authors: H Cui, S Banerjee, S Guo, N Xie, G Liu
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Neither Lys- and DAP-type peptidoglycans stimulate mouse or human innate immune cells via Toll-like receptor 2
    Authors: M Langer, AW Girton, NI Popescu, T Burgett, JP Metcalf, KM Coggeshall
    PLoS ONE, 2018;13(2):e0193207.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  84. Anti-TLR2 antibody triggers oxidative phosphorylation in microglia and increases phagocytosis of ?-amyloid
    Authors: A Rubio-Arai, OM Finucane, S Keogh, MA Lynch
    J Neuroinflammation, 2018;15(1):247.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival
    Authors: K Subramania, DR Neill, HA Malak, L Spelmink, S Khandaker, G Dalla Libe, E Dearing, A Kirby, M Yang, A Achour, J Nilvebrant, PÅ Nygren, L Plant, A Kadioglu, B Henriques-
    Nat Microbiol, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  86. Induction of Kr�ppel-like factor 2 reduces K/BxN serum-induced arthritis
    Authors: M Das, D Laha, S Kanji, M Joseph, R Aggarwal, OH Iwenofu, VJ Pompili, MK Jain, H Das
    J. Cell. Mol. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  87. The Long Pentraxin 3 Plays a Role in Bone Turnover and Repair
    Authors: D Gr?evi?, M Sironi, S Valentino, L Deban, H Cvija, A Inforzato, N Kova?i?, V Katavi?, T Kelava, I Kalajzi?, A Mantovani, B Bottazzi
    Front Immunol, 2018;9(0):417.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Neogambogic Acid Suppresses Receptor Activator of Nuclear Factor ?B Ligand (RANKL)-Induced Osteoclastogenesis by Inhibiting the JNK and NF-?B Pathways in Mouse Bone Marrow-Derived Monocyte/Macrophages
    Authors: G Jin, FF Wang, T Li, DD Jia, Y Shen, HC Xu
    Med. Sci. Monit., 2018;24(0):2569-2577.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Poria cocos polysaccharide attenuates RANKL-induced osteoclastogenesis by suppressing NFATc1 activity and phosphorylation of ERK and STAT3
    Authors: D Song, Z Cao, J Tickner, H Qiu, C Wang, K Chen, Z Wang, C Guo, S Dong, J Xu
    Arch. Biochem. Biophys., 2018;647(0):76-83.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Cell Culture
  90. Protective Role of the MER Tyrosine Kinase via Efferocytosis in Rheumatoid Arthritis Models
    Authors: CEJ Waterborg, S Beermann, MGA Broeren, MB Bennink, MI Koenders, PLEM van Lent, WB van den Be, PM van der Kr, FAJ van de Loo
    Front Immunol, 2018;9(0):742.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Protease-Activated Receptor-2 Plays a Critical Role in Vascular Inflammation and Atherosclerosis in Apolipoprotein E-Deficient Mice
    Authors: T Hara, PT Phuong, D Fukuda, K Yamaguchi, C Murata, S Nishimoto, S Yagi, K Kusunose, H Yamada, T Soeki, T Wakatsuki, I Imoto, M Shimabukur, M Sata
    Circulation, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Systemic administration of ?-glucan of 200�kDa modulates melanoma microenvironment and suppresses metastatic cancer
    Authors: M Zhang, L Chun, V Sandoval, H Graor, J Myers, J Nthale, P Rauhe, Z Senders, K Choong, AY Huang, J Kim
    Oncoimmunology, 2018;7(2):e1387347.
    Species: Mouse
    Sample Types: Whole Cell
    Applications: Cell Culture
  93. Sphingosine 1-phosphate receptors regulate TLR4-induced CXCL5 release from astrocytes and microglia
    Authors: SA O'Sullivan, C O'Sullivan, LM Healy, KK Dev, GK Sheridan
    J. Neurochem., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  94. Toll-Interacting Protein, Tollip, Inhibits IL-13-Mediated Pulmonary Eosinophilic Inflammation in Mice
    Authors: Y Ito, N Schaefer, A Sanchez, D Francisco, R Alam, RJ Martin, JG Ledford, C Stevenson, D Jiang, L Li, M Kraft, HW Chu
    J Innate Immun, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Hyperactivation of Nrf2 leads to hypoplasia of bone in vivo
    Authors: E Yoshida, T Suzuki, M Morita, K Taguchi, K Tsuchida, H Motohashi, M Doita, M Yamamoto
    Genes Cells, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  96. TNF-?-mediated ER stress causes elimination of Mycobacterium fortuitum reservoirs by macrophage apoptosis
    Authors: SM Oh, YJ Lim, JA Choi, J Lee, SN Cho, D Go, SH Kim, CH Song
    FASEB J., 2018;0(0):fj201701407R.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  97. OC-STAMP promotes osteoclast fusion for pathogenic bone resorption in periodontitis via up-regulation of permissive fusogen CD9
    Authors: T Ishii, M Ruiz-Torru, A Ikeda, S Shindo, A Movila, H Mawardi, A Albassam, RA Kayal, AA Al-Dharrab, K Egashira, W Wisitrasam, K Yamamoto, AI Mira, K Sueishi, X Han, MA Taubman, T Miyamoto, T Kawai
    FASEB J., 2018;0(0):fj201701424R.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  98. Adenosine Areceptor (A2AR) stimulation modulates expression of semaphorins 4D and 3A, regulators of bone homeostasis
    Authors: A Mediero, T Wilder, L Shah, BN Cronstein
    FASEB J., 2018;0(0):fj201700217R.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation
  99. ISRE-Reporter Mouse Reveals High Basal and Induced Type I IFN Responses in Inflammatory Monocytes
    Authors: MB Uccellini, A García-Sas
    Cell Rep, 2018;25(10):2784-2796.e3.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. PGC1? Organizes the Osteoclast Cytoskeleton by Mitochondrial Biogenesis and Activation
    Authors: Y Zhang, N Rohatgi, DJ Veis, J Schilling, SL Teitelbaum, W Zou
    J. Bone Miner. Res., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  101. High-Resolution Mapping and Dynamics of the Transcriptome, Transcription Factors, and Transcription Co-Factor Networks in Classically and Alternatively Activated Macrophages
    Authors: A Das, CS Yang, S Arifuzzama, S Kim, SY Kim, KH Jung, YS Lee, YG Chai
    Front Immunol, 2018;9(0):22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Differentiation
  102. Monomeric C-Reactive Protein Binds and Neutralizes Receptor Activator of NF-?B Ligand-Induced Osteoclast Differentiation
    Authors: ZK Jia, HY Li, YL Liang, LA Potempa, SR Ji, Y Wu
    Front Immunol, 2018;9(0):234.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner
    Authors: M Datta, O Staszewski, E Raschi, M Frosch, N Hagemeyer, TL Tay, T Blank, M Kreutzfeld, D Merkler, S Ziegler-Wa, P Matthias, M Meyer-Lueh, M Prinz
    Immunity, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. Exosomes released from tumor-associated macrophages transfer miRNAs that induce a Treg/Th17 cell imbalance in epithelial ovarian cancer
    Authors: J Zhou, X Li, X Wu, T Zhang, Q Zhu, X Wang, H Wang, K Wang, Y Lin, X Wang
    Cancer Immunol Res, 2018;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  105. Elevated extracellular calcium ions promote proliferation and migration of mesenchymal stem cells via increasing osteopontin expression
    Authors: MN Lee, HS Hwang, SH Oh, A Roshanzade, JW Kim, JH Song, ES Kim, JT Koh
    Exp. Mol. Med., 2018;50(11):142.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Inhibition of STAT5A promotes osteogenesis by DLX5 regulation
    Authors: KM Lee, KH Park, JS Hwang, M Lee, DS Yoon, HA Ryu, HS Jung, KW Park, J Kim, SW Park, SH Kim, YM Chun, WJ Choi, JW Lee
    Cell Death Dis, 2018;9(11):1136.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  107. An immune cell spray (ICS) formulation allows for the delivery of functional monocyte/macrophages
    Authors: V Beneke, F Küster, AL Neehus, C Hesse, E Lopez-Rodr, K Haake, A Rafiei Has, JW Schott, D Walter, A Braun, WF Wolkers, M Ackermann, N Lachmann
    Sci Rep, 2018;8(1):16281.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. HIF prolyl hydroxylase inhibition protects skeletal muscle from eccentric contraction-induced injury
    Authors: AN Billin, SE Honeycutt, AV McDougal, JP Kerr, Z Chen, JM Freudenber, DK Rajpal, G Luo, HF Kramer, RS Geske, F Fang, B Yao, RV Clark, J Lepore, A Cobitz, R Miller, K Nosaka, AC Hinken, AJ Russell
    Skelet Muscle, 2018;8(1):35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  109. Protective effects of a traditional herbal extract from Stellaria dichotoma var. lanceolata against Mycobacterium abscessus infections
    Authors: SJ Bae, JW Choi, BJ Park, J Lee, EK Jo, YH Lee, SB Kim, JM Yuk
    PLoS ONE, 2018;13(11):e0207696.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  110. Targeted disruption of adenosine kinase in myeloid monocyte cells increases osteoclastogenesis and bone resorption in mice
    Authors: Q Ye, G Li, S Liu, Y Guan, Y Li, J Li, H Jia, X Li, Q Li, R Huang, H Wang, Y Zhang
    Int. J. Mol. Med., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  111. Fraxinellone Attenuates Rheumatoid Inflammation in Mice
    Authors: SM Jung, J Lee, SY Baek, J Lee, SG Jang, SM Hong, JS Park, ML Cho, SH Park, SK Kwok
    Int J Mol Sci, 2018;19(3):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  112. Short-chain fatty acids regulate systemic bone mass and protect from pathological bone loss
    Authors: S Lucas, Y Omata, J Hofmann, M Böttcher, A Iljazovic, K Sarter, O Albrecht, O Schulz, B Krishnacou, G Krönke, M Herrmann, D Mougiakako, T Strowig, G Schett, MM Zaiss
    Nat Commun, 2018;9(1):55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. LncRNA-AK131850 Sponges MiR-93-5p in Newborn and Mature Osteoclasts to Enhance the Secretion of Vascular Endothelial Growth Factor a Promoting Vasculogenesis of Endothelial Progenitor Cells
    Authors: H Quan, M Liang, N Li, C Dou, C Liu, Y Bai, W Luo, J Li, F Kang, Z Cao, X Yang, H Jiang, S Dong
    Cell. Physiol. Biochem., 2018;46(1):401-417.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. A novel prospective isolation of murine fetal liver progenitors to study in utero hematopoietic defects
    Authors: JE Draper, P Sroczynska, MZH Fadlullah, R Patel, G Newton, W Breitwiese, V Kouskoff, G Lacaud
    PLoS Genet., 2018;14(1):e1007127.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  115. Increased A20-E3 ubiquitin ligase interactions in bid-deficient glia attenuate TLR3- and TLR4-induced inflammation
    Authors: S Kinsella, M Fichtner, O Watters, HG König, JHM Prehn
    J Neuroinflammation, 2018;15(1):130.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  116. Microbiota Reconstitution Does Not Cause Bone Loss in Germ-Free Mice
    Authors: D Quach, F Collins, N Parameswar, L McCabe, RA Britton
    mSphere, 2018;3(1):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  117. CD82 hypomethylation is essential for tuberculosis pathogenesis via regulation of RUNX1-Rab5/22
    Authors: HJ Koh, YR Kim, JS Kim, JS Yun, S Kim, SY Kim, K Jang, CS Yang
    Exp. Mol. Med., 2018;50(5):62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  118. Fc? receptor-mediated influx of S100A8/A9-producing neutrophils as inducer of bone erosion during antigen-induced arthritis
    Authors: I Di Ceglie, G Ascone, NAJ Cremers, AW Sloetjes, B Walgreen, T Vogl, J Roth, JS Verbeek, FAJ van de Loo, MI Koenders, PM van der Kr, AB Blom, MHJ van den Bo, PLEM van Lent
    Arthritis Res. Ther., 2018;20(1):80.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Allogeneic transplantation of programmable cells of monocytic origin (PCMO) improves angiogenesis and tissue recovery in critical limb ischemia (CLI): a translational approach
    Authors: R Berndt, L Hummitzsch, K He beta, M Albrecht, K Zitta, R Rusch, B Sarras, A Bayer, J Cremer, F Faendrich, J Gro beta
    Stem Cell Res Ther, 2018;9(1):117.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  120. A Bach2-Cebp Gene Regulatory Network for the Commitment of Multipotent Hematopoietic Progenitors
    Authors: A Itoh-Nakad, M Matsumoto, H Kato, J Sasaki, Y Uehara, Y Sato, R Ebina-Shib, M Morooka, R Funayama, K Nakayama, K Ochiai, A Muto, K Igarashi
    Cell Rep, 2017;18(10):2401-2414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  121. Hypomorphic A20 expression confers susceptibility to psoriasis
    Authors: A Aki, M Nagasaki, BA Malynn, A Ma, T Kagari
    PLoS ONE, 2017;12(6):e0180481.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  122. 25-hydroxycholesterol promotes RANKL-induced osteoclastogenesis through coordinating NFATc1 and Sp1 complex in the transcription of miR-139-5p
    Authors: L Zhang, Y Lv, G Xian, Y Lin
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  123. Tumor-Associated Macrophages Suppress the Cytotoxic Activity of Antimitotic Agents
    Authors: OC Olson, H Kim, DF Quail, EA Foley, JA Joyce
    Cell Rep, 2017;19(1):101-113.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  124. Commensal Gut Microbiota Immunomodulatory Actions in Bone Marrow and Liver have Catabolic Effects on Skeletal Homeostasis in Health
    Authors: CM Novince, CR Whittow, JD Aartun, JD Hathaway, N Poulides, MB Chavez, HM Steinkamp, KA Kirkwood, E Huang, C Westwater, KL Kirkwood
    Sci Rep, 2017;7(1):5747.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. NF-?B activation is critical for bacterial lipoprotein tolerance-enhanced bactericidal activity in macrophages during microbial infection
    Authors: J Liu, J Xiang, X Li, S Blankson, S Zhao, J Cai, Y Jiang, HP Redmond, JH Wang
    Sci Rep, 2017;7(0):40418.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  126. OCLI-023, a Novel Pyrimidine Compound, Suppresses Osteoclastogenesis In Vitro and Alveolar Bone Resorption In Vivo
    Authors: HJ Ihn, T Lee, JA Kim, D Lee, ND Kim, HI Shin, YC Bae, EK Park
    PLoS ONE, 2017;12(1):e0170159.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  127. Glial cells are functionally impaired in juvenile neuronal ceroid lipofuscinosis and detrimental to neurons
    Authors: L Parviainen, S Dihanich, GW Anderson, AM Wong, HR Brooks, R Abeti, P Rezaie, G Lalli, S Pope, SJ Heales, HM Mitchison, BP Williams, JD Cooper
    Acta Neuropathol Commun, 2017;5(1):74.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  128. Barley Seedling Extracts Inhibit RANKL-Induced Differentiation, Fusion, and Maturation of Osteoclasts in the Early-to-Late Stages of Osteoclastogenesis
    Authors: SW Choi, SH Kim, KS Lee, HJ Kang, MJ Lee, KI Park, JH Lee, KD Park, WD Seo
    Evid Based Complement Alternat Med, 2017;2017(0):6072573.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Metabolic origins of spatial organization in the tumor microenvironment
    Authors: C Carmona-Fo, M Deforet, L Akkari, CB Thompson, JA Joyce, JB Xavier
    Proc. Natl. Acad. Sci. U.S.A, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  130. Scaling of titanium implants entrains inflammation-induced osteolysis
    Authors: M Eger, N Sterer, T Liron, D Kohavi, Y Gabet
    Sci Rep, 2017;7(0):39612.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  131. Inhibition of lipopolysaccharide-induced osteoclast formation and bone resorption in vitro and in vivo by cysteine proteinase inhibitors
    Authors: F Strålberg, A Kassem, F Kasprzykow, M Abrahamson, A Grubb, C Lindholm, UH Lerner
    J. Leukoc. Biol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. CCL11, a novel mediator of inflammatory bone resorption
    Authors: E Kindstedt, CK Holm, R Sulniute, I Martinez-C, R Lundmark, P Lundberg
    Sci Rep, 2017;7(1):5334.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  133. Inositol polyphosphate multikinase promotes Toll-like receptor-induced inflammation by stabilizing TRAF6
    Authors: E Kim, J Beon, S Lee, SJ Park, H Ahn, MG Kim, JE Park, W Kim, JM Yuk, SJ Kang, SH Lee, EK Jo, RH Seong, S Kim
    Sci Adv, 2017;3(4):e1602296.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  134. Colony-stimulating factor 1 receptor blockade inhibits tumor growth by altering the polarization of tumor-associated macrophages in hepatocellular carcinoma
    Authors: JY Ao, XD Zhu, ZT Chai, H Cai, YY Zhang, KZ Zhang, LQ Kong, N Zhang, BG Ye, DN Ma, HC Sun
    Mol. Cancer Ther., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  135. ESRRA (estrogen related receptor, alpha) is a key coordinator of transcriptional and post-translational activation of autophagy to promote innate host defense
    Authors: SY Kim, CS Yang, HM Lee, JK Kim, YS Kim, YR Kim, JS Kim, TS Kim, JM Yuk, CR Dufour, SH Lee, JM Kim, HS Choi, V Giguère, EK Jo
    Autophagy, 2017;0(0):0.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Small leucine rich proteoglycans, a novel link to osteoclastogenesis
    Authors: V Kram, TM Kilts, N Bhattachar, L Li, MF Young
    Sci Rep, 2017;7(1):12627.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. The influence of macrophage growth factors on Theiler's Murine Encephalomyelitis Virus (TMEV) infection and activation of macrophages
    Authors: KM Schneider, NB Watson, SB Minchenber, PT Massa
    Cytokine, 2017;0(0):.
  138. Theranostic Nucleic Acid Binding Nanoprobe Exerts Anti-inflammatory and Cytoprotective Effects in Ischemic Injury
    Authors: HH Chen, H Yuan, H Cho, Y Feng, S Ngoy, AT Kumar, R Liao, W Chao, L Josephson, DE Sosnovik
    Theranostics, 2017;7(4):814-825.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  139. The Cytokine Response to Lipopolysaccharide Does Not Predict the Host Response to Infection
    Authors: BA Fensterhei, Y Guo, ER Sherwood, JK Bohannon
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  140. Activity-independent targeting of mTOR to lysosomes in primary osteoclasts
    Authors: A Wang, LR Carraro-La, C Owen, B Gao, PN Corey, P Tyrrell, JH Brumell, I Voronov
    Sci Rep, 2017;7(1):3005.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  141. TRPV1 deletion impaired fracture healing and inhibited osteoclast and osteoblast differentiation
    Authors: LH He, M Liu, Y He, E Xiao, L Zhao, T Zhang, HQ Yang, Y Zhang
    Sci Rep, 2017;7(0):42385.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  142. Toxoplasma gondii GRA7-Targeted ASC and PLD1 Promote Antibacterial Host Defense via PKC�
    Authors: HJ Koh, YR Kim, JS Kim, JS Yun, K Jang, CS Yang
    PLoS Pathog, 2017;13(1):e1006126.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  143. CLEC5A is a critical receptor in innate immunity against Listeria infection
    Authors: ST Chen, FJ Li, TY Hsu, SM Liang, YC Yeh, WY Liao, TY Chou, NJ Chen, M Hsiao, WB Yang, SL Hsieh
    Nat Commun, 2017;8(1):299.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  144. STING-Dependent Signaling Underlies IL-10 Controlled Inflammatory Colitis
    Authors: J Ahn, S Son, SC Oliveira, GN Barber
    Cell Rep, 2017;21(13):3873-3884.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  145. Lyn and Fyn function as molecular switches that control immunoreceptors to direct homeostasis or inflammation
    Authors: SB Mkaddem, A Murua, H Flament, D Titeca-Bea, C Bounaix, L Danelli, P Launay, M Benhamou, U Blank, E Daugas, N Charles, RC Monteiro
    Nat Commun, 2017;8(1):246.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  146. Metformin Mediates Protection against Legionella Pneumonia through Activation of AMPK and Mitochondrial Reactive Oxygen Species
    Authors: C Kajiwara, Y Kusaka, S Kimura, T Yamaguchi, Y Nanjo, Y Ishii, H Udono, TJ Standiford, K Tateda
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  147. Up-Regulation of RANK Expression via ERK1/2 by Insulin Contributes to the Enhancement of Osteoclast Differentiation
    Authors: JH Oh, NK Lee
    Mol. Cells, 2017;40(5):371-377.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  148. Interleukin-13 reduces cardiac injury and prevents heart dysfunction in viral myocarditis via enhanced M2 macrophage polarization
    Authors: H Yang, Y Chen, C Gao
    Oncotarget, 2017;8(59):99495-99503.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Irisin prevents and restores bone loss and muscle atrophy in hind-limb suspended mice
    Authors: G Colaianni, T Mongelli, C Cuscito, P Pignataro, L Lippo, G Spiro, A Notarnicol, I Severi, G Passeri, G Mori, G Brunetti, B Moretti, U Tarantino, SC Colucci, JE Reseland, R Vettor, S Cinti, M Grano
    Sci Rep, 2017;7(1):2811.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  150. The PSMP-CCR2 interactions trigger monocyte/macrophage-dependent colitis
    Authors: X Pei, D Zheng, S She, J Ma, C Guo, X Mo, Y Zhang, Q Song, Y Zhang, D Ma, Y Wang
    Sci Rep, 2017;7(1):5107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  151. The HIV co-receptor CCR5 regulates osteoclast function
    Authors: JW Lee, A Hoshino, K Inoue, T Saitou, S Uehara, Y Kobayashi, S Ueha, K Matsushima, A Yamaguchi, Y Imai, T Iimura
    Nat Commun, 2017;8(1):2226.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis
    Authors: EM Grössinger, M Kang, L Bouchareyc, R Sarin, DR Haudenschi, LN Borodinsky, IE Adamopoulo
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  153. Pharmacological HIF-inhibition attenuates postoperative adhesion formation
    Authors: MJ Strowitzki, AS Ritter, P Radhakrish, JM Harnoss, VM Opitz, M Biller, J Wehrmann, U Keppler, J Scheer, M Wallwiener, T Schmidt, A Ulrich, M Schneider
    Sci Rep, 2017;7(1):13151.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  154. IL-33 contributes to sepsis-induced long-term immunosuppression by expanding the regulatory T cell population
    Authors: DC Nascimento, PH Melo, AR Piñeros, RG Ferreira, DF Colón, PB Donate, FV Castanheir, A Gozzi, PG Czaikoski, W Niedbala, MC Borges, DS Zamboni, FY Liew, FQ Cunha, JC Alves-Filh
    Nat Commun, 2017;8(0):14919.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  155. Muramyl Dipeptide, a Shared Structural Motif of Peptidoglycans, Is a Novel Inducer of Bone Formation through Induction of Runx2
    Authors: OJ Park, J Kim, J Yang, CH Yun, SH Han
    J. Bone Miner. Res, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. PEDF mediates pathological neovascularization by regulating macrophage recruitment and polarization in the mouse model of oxygen-induced retinopathy
    Authors: S Gao, C Li, Y Zhu, Y Wang, A Sui, Y Zhong, B Xie, X Shen
    Sci Rep, 2017;7(0):42846.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  157. PPAR-? Activation Mediates Innate Host Defense through Induction of TFEB and Lipid Catabolism
    Authors: YS Kim, HM Lee, JK Kim, CS Yang, TS Kim, M Jung, HS Jin, S Kim, J Jang, GT Oh, JM Kim, EK Jo
    J. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  158. MiR-30a attenuates osteoclastogenesis via targeting DC-STAMP-c-Fos-NFATc1 signaling
    Authors: Y Yin, L Tang, J Chen, X Lu
    Am J Transl Res, 2017;9(12):5743-5753.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  159. Preferred M2 Polarization by ASC-Based Hydrogel Accelerated Angiogenesis and Myogenesis in Volumetric Muscle Loss Rats
    Authors: H Huang, J Liu, H Hao, D Chen, L Zhizhong, M Li, H Song, R Xiang, C Jiang, X Fu, W Han
    Stem Cells Int, 2017;2017(0):2896874.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  160. Specific calpain inhibition protects kidney against inflammaging
    Authors: G Hanouna, L Mesnard, S Vandermeer, J Perez, S Placier, JP Haymann, F Campagne, J Moroch, A Bataille, L Baud, E Letavernie
    Sci Rep, 2017;7(1):8016.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  161. Extracellular MicroRNAs Induce Potent Innate Immune Responses via TLR7/MyD88-Dependent Mechanisms
    Authors: Y Feng, L Zou, D Yan, H Chen, G Xu, W Jian, P Cui, W Chao
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Gastrodin inhibits osteoclastogenesis via down-regulating the NFATc1 signaling pathway and stimulates osseointegration in vitro
    Authors: F Zhou, Y Shen, B Liu, X Chen, L Wan, D Peng
    Biochem. Biophys. Res. Commun, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  163. Negative regulation of NF-?B p65 activity by serine 536 phosphorylation.
    Authors: Jean-Philippe Pradère, Céline Hernandez, Christiane Koppe, Richard A Friedman, Tom Luedde, Robert F Schwabe
    Science Signaling, 2016;0(0):1937-9145.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  164. TLR9 Deficiency Leads to Accelerated Renal Disease and Myeloid Lineage Abnormalities in Pristane-Induced Murine Lupus
    Authors: L Bossaller, A Christ, K Pelka, K Nündel, PI Chiang, C Pang, N Mishra, P Busto, RG Bonegio, RE Schmidt, E Latz, A Marshak-Ro
    J. Immunol., 2016;197(4):1044-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Anti-Inflammatory Effects of Metformin Irrespective of Diabetes Status
    Circ Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  166. Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation
    Neuropharmacology, 2016;114(0):88-100.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  167. VISTA deficiency accelerates the development of fatal murine lupus nephritis
    Authors: Sabrina Ceeraz
    Arthritis & rheumatology (Hoboken, N.J.), 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Characterization of a novel adult murine immortalized microglial cell line and its activation by amyloid-beta.
    Authors: McCarthy R, Lu D, Alkhateeb A, Gardeck A, Lee C, Wessling-Resnick M
    J Neuroinflammation, 2016;13(1):21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  169. The Role of Prostate Apoptosis Response-4 (Par-4) in Mycobacterium tuberculosis Infected Macrophages
    Sci Rep, 2016;6(0):32079.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  170. The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity
    Cell, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. Analysis of the Effects of the Bruton's tyrosine kinase (Btk) Inhibitor Ibrutinib on Monocyte Fc? Receptor (Fc?R) Function
    Authors: L Ren, A Campbell, H Fang, S Gautam, S Elavazhaga, K Fatehchand, P Mehta, A Stiff, BF Reader, X Mo, JC Byrd, WE Carson, JP Butchar, S Tridandapa
    J. Biol. Chem, 2016;291(6):3043-52.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. The role of MyD88- and TRIF-dependent signaling in monophosphoryl lipid A-induced expansion and recruitment of innate immunocytes.
    Authors: Hernandez A, Bohannon J, Luan L, Fensterheim B, Guo Y, Patil N, McAdams C, Wang J, Sherwood E
    J Leukoc Biol, 2016;100(6):1311-1322.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Multiple myeloma-derived MMP-13 mediates osteoclast fusogenesis and osteolytic disease
    Authors: J Fu, S Li, R Feng, H Ma, F Sabeh, GD Roodman, J Wang, S Robinson, XE Guo, T Lund, D Normolle, MY Mapara, SJ Weiss, S Lentzsch
    J Clin Invest, 2016;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  174. Inhibition of cathepsin X reduces the strength of microglial-mediated neuroinflammation
    Authors: Janko Kos
    Neuropharmacology, 2016;114(0):88-100.
    Species: Mouse
    Sample Types: Whole Cells
  175. Roles of endoplasmic reticulum stress-mediated apoptosis in M1-polarized macrophages during mycobacterial infections
    Sci Rep, 2016;6(0):37211.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  176. TREM2 deficiency reduces the efficacy of immunotherapeutic amyloid clearance
    EMBO Mol Med, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Brucella abortus Invasion of Osteocytes Modulates Connexin 43 and Integrin Expression and Induces Osteoclastogenesis via Receptor Activator of NF-kappaB Ligand and Tumor Necrosis Factor Alpha Secretion.
    Authors: Pesce Viglietti A, Arriola Benitez P, Gentilini M, Velasquez L, Fossati C, Giambartolomei G, Delpino M
    Infect Immun, 2016;84(1):11-20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  178. Adipokine Chemerin Bridges Metabolic Dyslipidemia and Alveolar Bone Loss in Mice
    Authors: Erivan S Ramos-Juni
    J. Bone Miner. Res, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Docosahexaenoic acid signaling attenuates the proliferation and differentiation of bone marrow-derived osteoclast precursors and promotes apoptosis in mature osteoclasts
    Authors: Young-Ran Yoon
    Cell. Signal., 2016;29(0):226-232.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Cytoskeleton-centric protein transportation by exosomes transforms tumor-favorable macrophages
    Oncotarget, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  181. Negative regulation of bacterial killing and inflammation by two novel CD16 ligands
    Eur J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  182. Mycobacterium abscessus ESX-3 plays an important role in host inflammatory and pathological responses during infection
    Microbes Infect, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  183. Spatiotemporal expression of endogenous TLR4 ligands leads to inflammation and bone erosion in mouse collagen-induced arthritis
    Eur J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  184. Treatment with cestode parasite antigens recruits CCR2+ myeloid cells, the adoptive transfer of which ameliorates colitis
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Macrophages and cardiac fibroblasts are the main producers of eotaxins and regulate eosinophil trafficking to the heart
    Eur J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  186. Mycobacterium avium MAV2054 protein induces macrophage apoptosis by targeting mitochondria and reduces intracellular bacterial growth
    Sci Rep, 2016;6(0):37804.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  187. Theaflavin-3,3'-digallate represses osteoclastogenesis and prevents wear debris-induced osteolysis via suppression of ERK pathway
    Authors: Dechun Geng
    Acta Biomater, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  188. Dynamics of the sealing zone in cultured osteoclasts
    Authors: Sarit Batsir
    Cytoskeleton (Hoboken), 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  189. Prader-Willi Critical Region, a Non-Translated, Imprinted Central Regulator of Bone Mass: Possible Role in Skeletal Abnormalities in Prader-Willi Syndrome.
    Authors: Khor E, Fanshawe B, Qi Y, Zolotukhin S, Kulkarni R, Enriquez R, Purtell L, Lee N, Wee N, Croucher P, Campbell L, Herzog H, Baldock P
    PLoS ONE, 2016;11(1):e0148155.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  190. Defect density in multiwalled carbon nanotubes influences ovalbumin adsorption and promotes macrophage activation and CD4(+) T-cell proliferation
    Int J Nanomedicine, 2016;11(0):4357-71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  191. MicroRNAs: Potential Biomarkers and Therapeutic Targets for Alveolar Bone Loss in Periodontal Disease
    Int J Mol Sci, 2016;17(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  192. Immune complexes regulate bone metabolism through FcRgamma signalling.
    Authors: Negishi-Koga T, Gober H, Sumiya E, Komatsu N, Okamoto K, Sawa S, Suematsu A, Suda T, Sato K, Takai T, Takayanagi H
    Nat Commun, 2015;6(0):6637.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  193. Fasciola hepatica fatty acid binding protein inhibits TLR4 activation and suppresses the inflammatory cytokines induced by lipopolysaccharide in vitro and in vivo.
    Authors: Martin I, Caban-Hernandez K, Figueroa-Santiago O, Espino A
    J Immunol, 2015;194(8):3924-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Sexual Dimorphism in MAPK-Activated Protein Kinase-2 (MK2) Regulation of RANKL-Induced Osteoclastogenesis in Osteoclast Progenitor Subpopulations.
    Authors: Herbert B, Valerio M, Gaestel M, Kirkwood K
    PLoS ONE, 2015;10(5):e0125387.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  195. Impaired macrophage autophagy increases the immune response in obese mice by promoting proinflammatory macrophage polarization.
    Authors: Liu K, Zhao E, Ilyas G, Lalazar G, Lin Y, Haseeb M, Tanaka K, Czaja M
    Autophagy, 2015;11(2):271-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  196. Regulation of L-type Voltage Gated Calcium Channel CACNA1S in Macrophages upon Mycobacterium tuberculosis Infection.
    Authors: Antony C, Mehto S, Tiwari B, Singh Y, Natarajan K
    PLoS ONE, 2015;10(4):e0124263.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  197. Activin A inhibits RANKL-mediated osteoclast formation, movement and function in murine bone marrow macrophage cultures.
    Authors: Fowler T, Kamalakar A, Akel N, Kurten R, Suva L, Gaddy D
    J Cell Sci, 2015;128(4):683-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  198. Pyruvate dehydrogenase kinase 1 participates in macrophage polarization via regulating glucose metabolism.
    Authors: Tan Z, Xie N, Cui H, Moellering D, Abraham E, Thannickal V, Liu G
    J Immunol, 2015;194(12):6082-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  199. Inhibitory Effects of KP-A159, a Thiazolopyridine Derivative, on Osteoclast Differentiation, Function, and Inflammatory Bone Loss via Suppression of RANKL-Induced MAP Kinase Signaling Pathway.
    Authors: Ihn H, Lee D, Lee T, Kim S, Shin H, Bae Y, Hong J, Park E
    PLoS ONE, 2015;10(11):e0142201.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Sim1 inhibits bone formation by enhancing the sympathetic tone in male mice.
    Authors: Wang X, Wei W, Zinn A, Wan Y
    Endocrinology, 2015;156(4):1408-15.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  201. Porphyromonas gingivalis Stimulates Bone Resorption by Enhancing RANKL (Receptor Activator of NF-kappaB Ligand) through Activation of Toll-like Receptor 2 in Osteoblasts.
    Authors: Kassem A, Henning P, Lundberg P, Souza P, Lindholm C, Lerner U
    J Biol Chem, 2015;290(33):20147-58.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  202. Netrin-1 is a critical autocrine/paracrine factor for osteoclast differentiation.
    Authors: Mediero A, Ramkhelawon B, Perez-Aso M, Moore K, Cronstein B
    J Bone Miner Res, 2015;30(5):837-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  203. CHMP5 controls bone turnover rates by dampening NF-kappaB activity in osteoclasts.
    Authors: Greenblatt M, Park K, Oh H, Kim J, Shin D, Lee J, Lee J, Singh A, Lee K, Hu D, Xiao C, Charles J, Penninger J, Lotinun S, Baron R, Ghosh S, Shim J
    J Exp Med, 2015;212(8):1283-301.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  204. MicroRNA-125a Inhibits Autophagy Activation and Antimicrobial Responses during Mycobacterial Infection.
    Authors: Kim J, Yuk J, Kim S, Kim T, Jin H, Yang C, Jo E
    J Immunol, 2015;194(11):5355-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  205. TNF Induction of NF-kappaB RelB Enhances RANKL-Induced Osteoclastogenesis by Promoting Inflammatory Macrophage Differentiation but also Limits It through Suppression of NFATc1 Expression.
    Authors: Zhao Z, Hou X, Yin X, Li Y, Duan R, Boyce B, Yao Z
    PLoS ONE, 2015;10(8):e0135728.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  206. Phosphorylation and linear ubiquitin direct A20 inhibition of inflammation.
    Authors: Wertz I, Newton K, Seshasayee D, Kusam S, Lam C, Zhang J, Popovych N, Helgason E, Schoeffler A, Jeet S, Ramamoorthi N, Kategaya L, Newman R, Horikawa K, Dugger D, Sandoval W, Mukund S, Zindal A, Martin F, Quan C, Tom J, Fairbrother W, Townsend M, Warming S, DeVoss J, Liu J, Dueber E, Caplazi P, Lee W, Goodnow C, Balazs M, Yu K, Kolumam G, Dixit V
    Nature, 2015;528(7582):370-5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  207. The clinically approved drugs dasatinib and bosutinib induce anti-inflammatory macrophages by inhibiting the salt-inducible kinases.
    Authors: Ozanne J, Prescott A, Clark K
    Biochem J, 2015;465(2):271-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  208. Network integration of parallel metabolic and transcriptional data reveals metabolic modules that regulate macrophage polarization.
    Authors: Jha A, Huang S, Sergushichev A, Lampropoulou V, Ivanova Y, Loginicheva E, Chmielewski K, Stewart K, Ashall J, Everts B, Pearce E, Driggers E, Artyomov M
    Immunity, 2015;42(3):419-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  209. Mouse Resistin (mRetn): cloning, expression and purification in Escherichia coli and the potential regulative effects on murine bone marrow hematopoiesis.
    Authors: Wang F, Gao J, Malisani A, Xi X, Han W, Wan X
    BMC Biotechnol, 2015;15(0):105.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  210. The Effects of Androgens on Murine Cortical Bone Do Not Require AR or ERalpha Signaling in Osteoblasts and Osteoclasts.
    Authors: Ucer S, Iyer S, Bartell S, Martin-Millan M, Han L, Kim H, Weinstein R, Jilka R, O'Brien C, Almeida M, Manolagas S
    J Bone Miner Res, 2015;30(7):1138-49.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  211. FTY720 inhibited proinflammatory cytokine release and osteoclastogenesis induced by Aggregatibacter actinomycetemcomitans.
    Authors: Yu H, Herbert B, Valerio M, Yarborough L, Hsu L, Argraves K
    Lipids Health Dis, 2015;14(0):66.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  212. GPCR-mediated PLCbetagamma/PKCbeta/PKD signaling pathway regulates the cofilin phosphatase slingshot 2 in neutrophil chemotaxis.
    Authors: Xu X, Gera N, Li H, Yun M, Zhang L, Wang Y, Wang Q, Jin T
    Mol Biol Cell, 2015;26(5):874-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  213. Macrophage-inducible C-type lectin Mincle-expressing dendritic cells contribute to control of splenic Mycobacterium bovis BCG infection in mice.
    Authors: Behler F, Maus R, Bohling J, Knippenberg S, Kirchhof G, Nagata M, Jonigk D, Izykowski N, Magel L, Welte T, Yamasaki S, Maus U
    Infect Immun, 2015;83(1):184-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  214. Small heterodimer partner interacts with NLRP3 and negatively regulates activation of the NLRP3 inflammasome.
    Authors: Yang C, Kim J, Kim T, Lee P, Kim S, Lee H, Shin D, Nguyen L, Lee M, Jin H, Kim K, Lee C, Kim M, Park S, Kim J, Choi H, Jo E
    Nat Commun, 2015;6(0):6115.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  215. A novel phthalimide derivative, TC11, has preclinical effects on high-risk myeloma cells and osteoclasts.
    Authors: Matsushita M, Ozaki Y, Hasegawa Y, Terada F, Tabata N, Shiheido H, Yanagawa H, Oikawa T, Matsuo K, Du W, Yamada T, Hozumi M, Ichikawa D, Hattori Y
    PLoS ONE, 2015;10(1):e0116135.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  216. 15-deoxy-delta12,14-prostaglandin j2 inhibits osteolytic breast cancer bone metastasis and estrogen deficiency-induced bone loss.
    Authors: Kim K, Kim H, Lee S, Ma G, Park K, Chung W
    PLoS ONE, 2015;10(4):e0122764.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  217. Targeted 25-hydroxyvitamin D3 1alpha-hydroxylase adoptive gene therapy ameliorates dss-induced colitis without causing hypercalcemia in mice.
    Authors: Li B, Baylink D, Walter M, Lau K, Meng X, Wang J, Cherkas A, Tang X, Qin X
    Mol Ther, 2015;23(2):339-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  218. WNT1-induced Secreted Protein-1 (WISP1), a Novel Regulator of Bone Turnover and Wnt Signaling.
    Authors: Maeda A, Ono M, Holmbeck K, Li L, Kilts T, Kram V, Noonan M, Yoshioka Y, McNerny E, Tantillo M, Kohn D, Lyons K, Robey P, Young M
    J Biol Chem, 2015;290(22):14004-18.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  219. Differential expression of claudin family members during osteoblast and osteoclast differentiation: Cldn-1 is a novel positive regulator of osteoblastogenesis.
    Authors: Alshbool F, Mohan S
    PLoS ONE, 2015;9(12):e114357.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  220. MicroRNA-188 regulates age-related switch between osteoblast and adipocyte differentiation.
    Authors: Li, Chang-Ju, Cheng, Peng, Liang, Meng-Ke, Chen, Yu-Si, Lu, Qiong, Wang, Jin-Yu, Xia, Zhu-Ying, Zhou, Hou-De, Cao, Xu, Xie, Hui, Liao, Er-Yuan, Luo, Xiang-Ha
    J Clin Invest, 2015;125(4):1509-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  221. Iron Chelation Inhibits Osteoclastic Differentiation In Vitro and in Tg2576 Mouse Model of Alzheimer's Disease.
    Authors: Guo J, Pan J, Xiong L, Xia W, Cui S, Xiong W
    PLoS ONE, 2015;10(11):e0139395.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  222. The ketone metabolite beta-hydroxybutyrate blocks NLRP3 inflammasome-mediated inflammatory disease.
    Authors: Youm Y, Nguyen K, Grant R, Goldberg E, Bodogai M, Kim D, D'Agostino D, Planavsky N, Lupfer C, Kanneganti T, Kang S, Horvath T, Fahmy T, Crawford P, Biragyn A, Alnemri E, Dixit V
    Nat Med, 2015;21(3):263-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  223. Anabolic bone formation via a site-specific bone-targeting delivery system by interfering with semaphorin 4D expression.
    Authors: Zhang Y, Wei L, Miron R, Shi B, Bian Z
    J Bone Miner Res, 2015;30(2):286-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  224. IL-1 receptor type 2 suppresses collagen-induced arthritis by inhibiting IL-1 signal on macrophages.
    Authors: Shimizu K, Nakajima A, Sudo K, Liu Y, Mizoroki A, Ikarashi T, Horai R, Kakuta S, Watanabe T, Iwakura Y
    J Immunol, 2015;194(7):3156-68.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  225. Bone Cell-autonomous Contribution of Type 2 Cannabinoid Receptor to Breast Cancer-induced Osteolysis.
    Authors: Sophocleous A, Marino S, Logan J, Mollat P, Ralston S, Idris A
    J Biol Chem, 2015;290(36):22049-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  226. ERK5 Activation Is Essential for Osteoclast Differentiation.
    Authors: Amano, Shigeru, Chang, Yu-Tzu, Fukui, Yasuhisa
    PLoS ONE, 2015;10(4):e0125054.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  227. Lipocalin (LCN) 2 Mediates Pro-Atherosclerotic Processes and Is Elevated in Patients with Coronary Artery Disease.
    Authors: Oberoi R, Bogalle E, Matthes L, Schuett H, Koch A, Grote K, Schieffer B, Schuett J, Luchtefeld M
    PLoS ONE, 2015;10(9):e0137924.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  228. Osteocytes produce interferon-beta as a negative regulator of osteoclastogenesis.
    Authors: Hayashida C, Ito J, Nakayachi M, Okayasu M, Ohyama Y, Hakeda Y, Sato T
    J Biol Chem, 2014;289(16):11545-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  229. Increased IL-6 expression in osteoclasts is necessary but not sufficient for the development of Paget's disease of bone.
    Authors: Teramachi J, Zhou H, Subler M, Kitagawa Y, Galson D, Dempster D, Windle J, Kurihara N, Roodman G
    J Bone Miner Res, 2014;29(6):1456-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  230. Regulation of osteoclast homeostasis and inflammatory bone loss by MFG-E8.
    Authors: Abe T, Shin J, Hosur K, Udey M, Chavakis T, Hajishengallis G
    J Immunol, 2014;193(3):1383-91.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  231. miR-27a regulates inflammatory response of macrophages by targeting IL-10.
    Authors: Xie N, Cui H, Banerjee S, Tan Z, Salomao R, Fu M, Abraham E, Thannickal V, Liu G
    J Immunol, 2014;193(1):327-34.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  232. NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.
    Authors: Noubade, Rajkumar, Wong, Kit, Ota, Naruhisa, Rutz, Sascha, Eidenschenk, Celine, Valdez, Patricia, Ding, Jiabing, Peng, Ivan, Sebrell, Andrew, Caplazi, Patrick, DeVoss, Jason, Soriano, Robert H, Sai, Tao, Lu, Rongze, Modrusan, Zora, Hackney, Jason, Ouyang, Wenjun
    Nature, 2014;509(7499):235-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  233. miR-34a blocks osteoporosis and bone metastasis by inhibiting osteoclastogenesis and Tgif2.
    Authors: Krzeszinski J, Wei W, Huynh H, Jin Z, Wang X, Chang T, Xie X, He L, Mangala L, Lopez-Berestein G, Sood A, Mendell J, Wan Y
    Nature, 2014;512(7515):431-5.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  234. Lipocalin 2 is a regulator of macrophage polarization and NF-kappaB/STAT3 pathway activation.
    Authors: Guo H, Jin D, Chen X
    Mol Endocrinol, 2014;28(10):1616-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  235. Aged mice are unable to mount an effective myeloid response to sepsis.
    Authors: Nacionales D, Gentile L, Vanzant E, Lopez M, Cuenca A, Cuenca A, Ungaro R, Li Y, Baslanti T, Bihorac A, Moore F, Baker H, Leeuwenburgh C, Moldawer L, Efron P
    J Immunol, 2014;192(2):612-22.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  236. Chloroquine reduces osteoclastogenesis in murine osteoporosis by preventing TRAF3 degradation.
    Authors: Xiu Y, Xu H, Zhao C, Li J, Morita Y, Yao Z, Xing L, Boyce B
    J Clin Invest, 2014;124(1):297-310.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  237. Changes of microRNA profile and microRNA-mRNA regulatory network in bones of ovariectomized mice.
    Authors: An J, Ohn J, Song J, Yang J, Park H, Choi H, Kim S, Kim S, Park W, Shin C
    J Bone Miner Res, 2014;29(3):644-56.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  238. Dual regulation of SPI1/PU.1 transcription factor by heat shock factor 1 (HSF1) during macrophage differentiation of monocytes.
    Authors: Jego G, Lanneau D, de Thonel A, Berthenet K, Hazoume A, Droin N, Hamman A, Girodon F, Bellaye P, Wettstein G, Jacquel A, Duplomb L, Le Mouel A, Papanayotou C, Christians E, Bonniaud P, Lallemand-Mezger V, Solary E, Garrido C
    Leukemia, 2014;28(8):1676-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  239. Myeloid-derived suppressor cells are involved in lysosomal acid lipase deficiency-induced endothelial cell dysfunctions.
    Authors: Zhao T, Ding X, Du H, Yan C
    J Immunol, 2014;193(4):1942-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  240. Bisphosphonates inhibit osteosarcoma-mediated osteolysis via attenuation of tumor expression of MCP-1 and RANKL.
    Authors: Ohba T, Cole H, Cates J, Slosky D, Haro H, Ando T, Schwartz H, Schoenecker J
    J Bone Miner Res, 2014;29(6):1431-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  241. FoxO proteins restrain osteoclastogenesis and bone resorption by attenuating H2O2 accumulation.
    Authors: Bartell, Shoshana, Kim, Ha-Neui, Ambrogini, Elena, Han, Li, Iyer, Srividhy, Serra Ucer, S, Rabinovitch, Peter, Jilka, Robert L, Weinstein, Robert S, Zhao, Haibo, O'Brien, Charles, Manolagas, Stavros, Almeida, Maria
    Nat Commun, 2014;5(0):3773.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  242. Identification of novel transcription factors in osteoclast differentiation using genome-wide analysis of open chromatin determined by DNase-seq.
    Authors: Inoue K, Imai Y
    J Bone Miner Res, 2014;29(8):1823-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  243. RasGRP3 limits Toll-like receptor-triggered inflammatory response in macrophages by activating Rap1 small GTPase.
    Authors: Tang, Songqing, Chen, Taoyong, Yu, Zhou, Zhu, Xuhui, Yang, Mingjin, Xie, Bin, Li, Nan, Cao, Xuetao, Wang, Jianli
    Nat Commun, 2014;5(0):4657.
  244. Comprehensive profiling analysis of actively resorbing osteoclasts identifies critical signaling pathways regulated by bone substrate.
    Authors: Purdue, P Edward, Crotti, Tania N, Shen, Zhenxin, Swantek, Jennifer, Li, Jun, Hill, Jonathan, Hanidu, Adedayo, Dimock, Janice, Nabozny, Gerald, Goldring, Steven R, McHugh, Kevin P
    Sci Rep, 2014;4(0):7595.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  245. Reactive oxygen species induce the association of SHP-1 with c-Src and the oxidation of both to enhance osteoclast survival.
    Authors: Ke K, Sul O, Choi E, Safdar A, Kim E, Choi H
    Am J Physiol Endocrinol Metab, 2014;307(1):E61-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  246. The pro-inflammatory cytokine, interleukin-6, enhances the polarization of alternatively activated macrophages.
    Authors: Fernando M, Reyes J, Iannuzzi J, Leung G, McKay D
    PLoS ONE, 2014;9(4):e94188.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  247. OX40L blockade is therapeutic in arthritis, despite promoting osteoclastogenesis.
    Authors: Gwyer Findlay, Emily, Danks, Lynett, Madden, Jodie, Cavanagh, Mary M, McNamee, Kay, McCann, Fiona, Snelgrove, Robert J, Shaw, Stevan, Feldmann, Marc, Taylor, Peter Ch, Horwood, Nicole J, Hussell, Tracy
    Proc Natl Acad Sci U S A, 2014;111(6):2289-94.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  248. Caspase-2 maintains bone homeostasis by inducing apoptosis of oxidatively-damaged osteoclasts.
    Authors: Sharma, Ramaswam, Callaway, Danielle, Vanegas, Difernan, Bendele, Michelle, Lopez-Cruzan, Marisa, Horn, Diane, Guda, Teja, Fajardo, Roberto, Abboud-Werner, Sherry, Herman, Brian
    PLoS ONE, 2014;9(4):e93696.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  249. An unexpected twist to the activation of IKKbeta: TAK1 primes IKKbeta for activation by autophosphorylation.
    Authors: Zhang J, Clark K, Lawrence T, Peggie M, Cohen P
    Biochem J, 2014;461(3):531-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  250. Preferential macrophage recruitment and polarization in LPS-induced animal model for COPD: noninvasive tracking using MRI.
    Authors: Al Faraj, Achraf, Sultana Shaik, Asma, Pureza, Mary Ang, Alnafea, Mohammad, Halwani, Rabih
    PLoS ONE, 2014;9(3):e90829.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  251. Cellular stress amplifies TLR3/4-induced CXCL1/2 gene transcription in mononuclear phagocytes via RIPK1.
    Authors: Zhao C, Pavicic P, Datta S, Sun D, Novotny M, Hamilton T
    J Immunol, 2014;193(2):879-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  252. Lysophosphatidic acid receptor type 1 (LPA1) plays a functional role in osteoclast differentiation and bone resorption activity.
    Authors: David M, Machuca-Gayet I, Kikuta J, Ottewell P, Mima F, LeBlanc R, Bonnelye E, Ribeiro J, Holen I, Lopez Vales R, Jurdic P, Chun J, Clezardin P, Ishii M, Peyruchaud O
    J Biol Chem, 2014;289(10):6551-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  253. C5L2 is required for C5a-triggered receptor internalization and ERK signaling.
    Authors: Hsu W, Yang F, Lin C, Hsieh S, Chen N
    Cell Signal, 2014;26(7):1409-19.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  254. The transcription factor T-box 3 regulates colony-stimulating factor 1-dependent Jun dimerization protein 2 expression and plays an important role in osteoclastogenesis.
    Authors: Yao C, Yao G, Sun B, Zhang C, Tommasini S, Insogna K
    J Biol Chem, 2014;289(10):6775-90.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  255. A novel TLR2-triggered signalling crosstalk synergistically intensifies TNF-mediated IL-6 induction.
    Authors: Chang Y, Chen T, Wu Y, Chen G, Weng T, Tseng P, Hsieh S, Fu S, Lin C, Chen C, Chu C, Chio I, Mak T, Chen N
    J Cell Mol Med, 2014;18(7):1344-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  256. NOTCH inhibits osteoblast formation in inflammatory arthritis via noncanonical NF-kappaB.
    Authors: Zhang H, Hilton M, Anolik J, Welle S, Zhao C, Yao Z, Li X, Wang Z, Boyce B, Xing L
    J Clin Invest, 2014;124(7):3200-14.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  257. Bone resorption is regulated by cell-autonomous negative feedback loop of Stat5-Dusp axis in the osteoclast.
    Authors: Hirose J, Masuda H, Tokuyama N, Omata Y, Matsumoto T, Yasui T, Kadono Y, Hennighausen L, Tanaka S
    J Exp Med, 2014;211(1):153-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  258. TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation.
    Authors: Sun Q, Sammut B, Wang F, Kurihara N, Windle J, Roodman G, Galson D
    J Bone Miner Res, 2014;29(1):90-102.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  259. Cardiac fibroblasts mediate IL-17A-driven inflammatory dilated cardiomyopathy.
    Authors: Wu L, Ong S, Talor M, Barin J, Baldeviano G, Kass D, Bedja D, Zhang H, Sheikh A, Margolick J, Iwakura Y, Rose N, Cihakova D
    J Exp Med, 2014;211(7):1449-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  260. Pathogenic conversion of Foxp3+ T cells into TH17 cells in autoimmune arthritis.
    Authors: Komatsu N, Okamoto K, Sawa S, Nakashima T, Oh-hora M, Kodama T, Tanaka S, Bluestone J, Takayanagi H
    Nat Med, 2014;20(1):62-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  261. Toll-like receptor 9 mediated responses in cardiac fibroblasts.
    Authors: Ohm I, Alfsnes K, Belland Olsen M, Ranheim T, Sandanger O, Dahl T, Aukrust P, Finsen A, Yndestad A, Vinge L
    PLoS ONE, 2014;9(8):e104398.
  262. Distinct actions of akt1 on skeletal architecture and function.
    Authors: Mukherjee, Aditi, Larson, Emily A, Klein, Robert F, Rotwein, Peter
    PLoS ONE, 2014;9(3):e93040.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  263. A nonapoptotic role for CASP2/caspase 2: modulation of autophagy.
    Authors: Tiwari, Meenaksh, Sharma, Lokendra, Vanegas, Difernan, Callaway, Danielle, Bai, Yidong, Lechleiter, James D, Herman, Brian
    Autophagy, 2014;10(6):1054-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  264. Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment.
    Authors: Chaturvedi, Pallavi, Gilkes, Daniele, Takano, Naoharu, Semenza, Gregg L
    Proc Natl Acad Sci U S A, 2014;111(20):E2120-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  265. SRT2104 extends survival of male mice on a standard diet and preserves bone and muscle mass.
    Authors: Mercken E, Mitchell S, Martin-Montalvo A, Minor R, Almeida M, Gomes A, Scheibye-Knudsen M, Palacios H, Licata J, Zhang Y, Becker K, Khraiwesh H, Gonzalez-Reyes J, Villalba J, Baur J, Elliott P, Westphal C, Vlasuk G, Ellis J, Sinclair D, Bernier M, de Cabo R
    Aging Cell, 2014;13(5):787-96.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  266. Microtubule dynamic instability controls podosome patterning in osteoclasts through EB1, cortactin, and Src.
    Authors: Biosse Duplan, Martin, Zalli, Detina, Stephens, Sebastie, Zenger, Serhan, Neff, Lynn, Oelkers, J Margit, Lai, Frank P, Horne, William, Rottner, Klemens, Baron, Roland
    Mol Cell Biol, 2014;34(1):16-29.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  267. Anti-osteoclastogenic activity of praeruptorin A via inhibition of p38/Akt-c-Fos-NFATc1 signaling and PLCgamma-independent Ca2+ oscillation.
    Authors: Yeon J, Kim K, Choi S, Moon S, Park Y, Ryu B, Oh J, Kim M, Erkhembaatar M, Son Y, Kim S
    PLoS ONE, 2014;9(2):e88974.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  268. DLX3 regulates bone mass by targeting genes supporting osteoblast differentiation and mineral homeostasis in vivo.
    Authors: Isaac, J, Erthal, J, Gordon, J, Duverger, O, Sun, H-W, Lichtler, A C, Stein, G S, Lian, J B, Morasso, M I
    Cell Death Differ, 2014;21(9):1365-76.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  269. T-cell costimulation protects obesity-induced adipose inflammation and insulin resistance.
    Authors: Zhong, Jixin, Rao, Xiaoquan, Braunstein, Zachary, Taylor, Anne, Narula, Vimal, Hazey, Jeffrey, Mikami, Dean, Needleman, Bradley, Rutsky, Jessica, Sun, Qinghua, Deiuliis, Jeffrey, Satoskar, Abhay R, Rajagopalan, Sanjay
    Diabetes, 2014;63(4):1289-302.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  270. Heparanase promotes lymphangiogenesis and tumor invasion in pancreatic neuroendocrine tumors.
    Authors: Hunter, K E, Palermo, C, Kester, J C, Simpson, K, Li, J-P, Tang, L H, Klimstra, D S, Vlodavsky, I, Joyce, J A
    Oncogene, 2014;33(14):1799-808.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  271. Unique macrophages different from M1/M2 macrophages inhibit T cell mitogenesis while upregulating Th17 polarization.
    Authors: Tatano Y, Shimizu T, Tomioka H
    Sci Rep, 2014;4(0):4146.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  272. MafB promotes atherosclerosis by inhibiting foam-cell apoptosis.
    Authors: Hamada, Michito, Nakamura, Megumi, Tran, Mai Thi, Moriguchi, Takashi, Hong, Cynthia, Ohsumi, Takayuki, Dinh, Tra Thi, Kusakabe, Manabu, Hattori, Motochik, Katsumata, Tokio, Arai, Satoko, Nakashima, Katsuhik, Kudo, Takashi, Kuroda, Etsushi, Wu, Chien-Hu, Kao, Pei-Han, Sakai, Masaharu, Shimano, Hitoshi, Miyazaki, Toru, Tontonoz, Peter, Takahashi, Satoru
    Nat Commun, 2014;5(0):3147.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  273. The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity.
    Authors: McMichael B, Scherer K, Franklin N, Lee B
    PLoS ONE, 2014;9(1):e87402.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  274. A crucial role for the ubiquitously expressed transcription factor Sp1 at early stages of hematopoietic specification.
    Authors: Gilmour J, Assi S, Jaegle U, Kulu D, van de Werken H, Clarke D, Westhead D, Philipsen S, Bonifer C
    Development, 2014;141(12):2391-401.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  275. EGCG attenuates autoimmune arthritis by inhibition of STAT3 and HIF-1alpha with Th17/Treg control.
    Authors: Yang E, Lee J, Lee S, Kim E, Moon Y, Jung Y, Park S, Cho M
    PLoS ONE, 2014;9(2):e86062.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  276. A macrophage-specific synthetic promoter for therapeutic application of adiponectin.
    Authors: Kang, W S, Kwon, J S, Kim, H B, Jeong, H-Y, Kang, H J, Jeong, M H, Cho, J G, Park, J C, Kim, Y S, Ahn, Y
    Gene Ther, 2014;21(4):353-62.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  277. Modulation of osteoclastogenesis with macrophage M1- and M2-inducing stimuli.
    Authors: Jeganathan S, Fiorino C, Naik U, Sun H, Harrison R
    PLoS ONE, 2014;9(8):e104498.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  278. Kruppel like factor 4 promoter undergoes active demethylation during monocyte/macrophage differentiation.
    Authors: Karpurapu M, Ranjan R, Deng J, Chung S, Lee Y, Xiao L, Nirujogi T, Jacobson J, Park G, Christman J
    PLoS ONE, 2014;9(4):e93362.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  279. IFN-gamma primes macrophage activation by increasing phosphatase and tensin homolog via downregulation of miR-3473b.
    Authors: Wu C, Xue Y, Wang P, Lin L, Liu Q, Li N, Xu J, Cao X
    J Immunol, 2014;193(6):3036-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  280. Swedish mutant APP suppresses osteoblast differentiation and causes osteoporotic deficit, which are ameliorated by N-acetyl-L-cysteine.
    Authors: Xia W, Jung J, Shun C, Xiong S, Xiong L, Shi X, Mei L, Xiong W
    J Bone Miner Res, 2013;28(10):2122-35.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  281. Overexpression of developmentally regulated GTP-binding protein-2 increases bone loss.
    Authors: Ke K, Sul O, Kim W, Lee M, Ko M, Suh J, Kim H, Kim S, Park J, Choi H
    Am J Physiol Endocrinol Metab, 2013;304(7):E703-10.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  282. Identification of a lupus-susceptibility locus leading to impaired clearance of apoptotic debris on New Zealand Black chromosome 13.
    Authors: Pau E, Loh C, Minty G, Chang N, Wither J
    Genes Immun, 2013;14(3):154-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  283. Osteoblast CFTR inactivation reduces differentiation and osteoprotegerin expression in a mouse model of cystic fibrosis-related bone disease.
    Authors: Stalvey M, Clines K, Havasi V, McKibbin C, Dunn L, Chung W, Clines G
    PLoS ONE, 2013;8(11):e80098.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  284. Fas-mediated inflammatory response in Listeria monocytogenes infection.
    Authors: Uchiyama R, Yonehara S, Tsutsui H
    J Immunol, 2013;190(8):4245-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  285. Identification, characterization, and isolation of a common progenitor for osteoclasts, macrophages, and dendritic cells from murine bone marrow and periphery.
    Authors: Jacome-Galarza C, Lee S, Lorenzo J, Aguila H
    J Bone Miner Res, 2013;28(5):1203-13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  286. Toll-like receptor 2 ligands regulate monocyte Fcgamma receptor expression and function.
    Authors: Shah P, Fatehchand K, Patel H, Fang H, Justiniano S, Mo X, Jarjoura D, Tridandapani S, Butchar J
    J Biol Chem, 2013;288(17):12345-52.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  287. Cloning and expression of feline colony stimulating factor receptor (CSF-1R) and analysis of the species specificity of stimulation by colony stimulating factor-1 (CSF-1) and interleukin-34 (IL-34).
    Cytokine, 2013;61(2):630-8.
    Species: Feline
    Sample Types: Whole Cells
    Applications: Bioassay
  288. IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation.
    Authors: Sandig H, Jobbings C, Roldan N, Whittingham-Dowd J, Orinska Z, Takeuchi O, Akira S, Bulfone-Paus S
    Eur J Immunol, 2013;43(4):979-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  289. Chemerin neutralization blocks hematopoietic stem cell osteoclastogenesis.
    Authors: Muruganandan S, Dranse H, Rourke J, McMullen N, Sinal C
    Stem Cells, 2013;31(10):2172-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  290. Caffeine enhances osteoclast differentiation and maturation through p38 MAP kinase/Mitf and DC-STAMP/CtsK and TRAP pathway.
    Authors: Choi J, Choi S, Lee S, Lee J, Kim H, Lee S, Lee N
    Cell Signal, 2013;25(5):1222-7.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  291. RNA interference-mediated silencing of Atp6i prevents both periapical bone erosion and inflammation in the mouse model of endodontic disease.
    Authors: Ma, Junqing, Chen, Wei, Zhang, Lijie, Tucker, Byron, Zhu, Guochun, Sasaki, Hajime, Hao, Liang, Wang, Lin, Ci, Honglian, Jiang, Hongbing, Stashenko, Philip, Li, Yi-Ping
    Infect Immun, 2013;81(4):1021-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  292. Liver X receptor activation inhibits osteoclastogenesis by suppressing NF-kappaB activity and c-Fos induction and prevents inflammatory bone loss in mice.
    Authors: Kim H, Yoon K, Yoon H, Hong J, Lee M, Lee I, Kim S
    J Leukoc Biol, 2013;94(1):99-107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  293. Acteoside suppresses RANKL-mediated osteoclastogenesis by inhibiting c-Fos induction and NF-kappaB pathway and attenuating ROS production.
    Authors: Lee S, Lee K, Yi S, Kook S, Lee J
    PLoS ONE, 2013;8(12):e80873.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  294. Vps35 loss promotes hyperresorptive osteoclastogenesis and osteoporosis via sustained RANKL signaling.
    Authors: Xia W, Tang F, Xiong L, Xiong S, Jung J, Lee D, Li X, Feng X, Mei L, Xiong W
    J Cell Biol, 2013;200(6):821-37.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  295. Identification of transcription factors for lineage-specific ESC differentiation.
    Authors: Yamamizu K, Piao Y, Sharov A, Zsiros V, Yu H, Nakazawa K, Schlessinger D, Ko M
    Stem Cell Reports, 2013;1(6):545-59.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  296. Differential immune responses to Segniliparus rotundus and Segniliparus rugosus infection and analysis of their comparative virulence profiles.
    Authors: Kim J, Kim W, Lee K, Won C, Kim J, Eum S, Koh W, Shin S
    PLoS ONE, 2013;8(3):e59646.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  297. The newly discovered cytokine IL-34 is expressed in gingival fibroblasts, shows enhanced expression by pro-inflammatory cytokines, and stimulates osteoclast differentiation.
    Authors: Bostrom E, Lundberg P
    PLoS ONE, 2013;8(12):e81665.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  298. Macrophages as IL-25/IL-33-responsive cells play an important role in the induction of type 2 immunity.
    Authors: Yang Z, Grinchuk V, Urban J, Bohl J, Sun R, Notari L, Yan S, Ramalingam T, Keegan A, Wynn T, Shea-Donohue T, Zhao A
    , 2013;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  299. Dectin-1 regulates IL-10 production via a MSK1/2 and CREB dependent pathway and promotes the induction of regulatory macrophage markers.
    Authors: Elcombe S, Naqvi S, van den Bosch M, Mackenzie K, Cianfanelli F, Brown G, Arthur J
    PLoS ONE, 2013;8(3):e60086.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  300. Mitogen-activated protein kinase 2 regulates physiological and pathological bone turnover.
    Authors: Braun T, Lepper J, Ruiz Heiland G, Hofstetter W, Siegrist M, Lezuo P, Gaestel M, Rumpler M, Thaler R, Klaushofer K, Distler J, Schett G, Zwerina J
    J Bone Miner Res, 2013;28(4):936-47.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  301. Talin1 and Rap1 are critical for osteoclast function.
    Authors: Zou W, Izawa T, Zhu T, Chappel J, Otero K, Monkley S, Critchley D, Petrich B, Morozov A, Ginsberg M, Teitelbaum S
    Mol Cell Biol, 2013;33(4):830-44.
  302. Lenalidomide inhibits lymphangiogenesis in preclinical models of mantle cell lymphoma.
    Authors: Song K, Herzog B, Sheng M, Fu J, McDaniel J, Chen H, Ruan J, Xia L
    Cancer Res, 2013;73(24):7254-64.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  303. Role of c-Jun N-terminal protein kinase 1/2 (JNK1/2) in macrophage-mediated MMP-9 production in response to Moraxella catarrhalis lipooligosaccharide (LOS).
    Authors: Hassan F, Ren D, Zhang W
    PLoS ONE, 2012;7(5):e37912.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  304. Regulatory T cells in the bone marrow microenvironment in patients with prostate cancer.
    Authors: Zhao E, Wang L, Dai J, Kryczek I, Wei S, Vatan L, Altuwaijri S, Sparwasser T, Wang G, Keller E, Zou W
    Oncoimmunology, 2012;1(2):152-161.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  305. Macrophages participate in IL-17-mediated inflammation.
    Authors: Barin JG, Baldeviano GC, Talor MV, Wu L, Ong S, Quader F, Chen P, Zheng D, Caturegli P, Rose NR, Cihakova D
    Eur. J. Immunol., 2012;42(3):726-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  306. Osteoprotection by semaphorin 3A.
    Authors: Hayashi M, Nakashima T, Taniguchi M, Kodama T, Kumanogoh A, Takayanagi H
    Nature, 2012;485(7396):69-74.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  307. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  308. Macrophage infiltration predicts a poor prognosis for human ewing sarcoma.
    Authors: Fujiwara T, Fukushi J, Yamamoto S, Matsumoto Y, Setsu N, Oda Y, Yamada H, Okada S, Watari K, Ono M, Kuwano M, Kamura S, Iida K, Okada Y, Koga M, Iwamoto Y
    Am. J. Pathol., 2011;179(3):1157-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  309. Inactivation of glycogen synthase kinase-3beta is required for osteoclast differentiation.
    Authors: Jang HD, Shin JH, Park DR, Hong JH, Yoon K, Ko R, Ko CY, Kim HS, Jeong D, Kim N, Lee SY
    J. Biol. Chem., 2011;286(45):39043-50.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  310. Smad1 signaling restricts hematopoietic potential after promoting hemangioblast commitment.
    Authors: Cook BD, Liu S, Evans T
    Blood, 2011;117(24):6489-97.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  311. Myeloid cells, BAFF, and IFN-gamma establish an inflammatory loop that exacerbates autoimmunity in Lyn-deficient mice.
    Authors: Scapini P, Hu Y, Chu CL
    J. Exp. Med., 2010;207(8):1757-73.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  312. B7-h3 augments the inflammatory response and is associated with human sepsis.
    Authors: Zhang G, Wang J, Kelly J
    J. Immunol., 2010;185(6):3677-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  313. Osteoclast inhibitory peptide-1 binding to the Fc gammaRIIB inhibits osteoclast differentiation.
    Authors: Shanmugarajan S, Beeson CC, Reddy SV
    Endocrinology, 2010;151(9):4389-99.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  314. Inhibition of osteoclastogenesis by mechanically loaded osteocytes: involvement of MEPE.
    Authors: Kulkarni RN, Bakker AD, Everts V, Klein-Nulend J
    Calcif. Tissue Int., 2010;87(5):461-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  315. Substance P stimulates bone marrow stromal cell osteogenic activity, osteoclast differentiation, and resorption activity in vitro.
    Authors: Wang L, Zhao R, Shi X, Wei T, Halloran BP, Clark DJ, Jacobs CR, Kingery WS
    Bone, 2009;45(2):309-20.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  316. Transient overexpression of sonic hedgehog alters the architecture and mechanical properties of trabecular bone.
    Authors: Kiuru M, Solomon J, Ghali B, van der Meulen M, Crystal RG, Hidaka C
    J. Bone Miner. Res., 2009;24(9):1598-607.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  317. Estrogen-dependent and C-C chemokine receptor-2-dependent pathways determine osteoclast behavior in osteoporosis.
    Authors: Binder NB, Niederreiter B, Hoffmann O, Stange R, Pap T, Stulnig TM, Mack M, Erben RG, Smolen JS, Redlich K
    Nat. Med., 2009;15(4):417-24.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  318. Milk fat globule EGF-8 promotes melanoma progression through coordinated Akt and twist signaling in the tumor microenvironment.
    Authors: Jinushi M, Nakazaki Y, Carrasco DR, Draganov D, Souders N, Johnson M, Mihm MC, Dranoff G
    Cancer Res., 2008;68(21):8889-98.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  319. Cardiotrophin-1 is an osteoclast-derived stimulus of bone formation required for normal bone remodeling.
    Authors: Walker EC, McGregor NE, Poulton IJ, Pompolo S, Allan EH, Quinn JM, Gillespie MT, Martin TJ, Sims NA
    J. Bone Miner. Res., 2008;23(12):2025-32.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  320. Estrogen protects bone by inducing Fas ligand in osteoblasts to regulate osteoclast survival.
    Authors: Krum SA, Miranda-Carboni GA, Hauschka PV, Carroll JS, Lane TF, Freedman LP, Brown M
    EMBO J., 2008;27(3):535-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  321. Microglia-derived interleukin-6 and leukaemia inhibitory factor promote astrocytic differentiation of neural stem/progenitor cells.
    Authors: Nakanishi M, Niidome T, Matsuda S, Akaike A, Kihara T, Sugimoto H
    Eur. J. Neurosci., 2007;25(3):649-58.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  322. Administration of cyclooxygenase-2 inhibitor reduces joint inflammation but exacerbates osteopenia in IL-1 alpha transgenic mice due to GM-CSF overproduction.
    Authors: Niki Y, Takaishi H, Takito J, Miyamoto T, Kosaki N, Matsumoto H, Toyama Y, Tada N
    J. Immunol., 2007;179(1):639-46.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  323. Imatinib promotes osteoblast differentiation by inhibiting PDGFR signaling and inhibits osteoclastogenesis by both direct and stromal cell-dependent mechanisms.
    Authors: O'Sullivan S, Naot D, Callon K, Porteous F, Horne A, Wattie D, Watson M, Cornish J, Browett P, Grey A
    J. Bone Miner. Res., 2007;22(11):1679-89.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  324. Bacterial lipopolysaccharide induces osteoclast formation in RAW 264.7 macrophage cells.
    Authors: Islam S, Hassan F, Tumurkhuu G, Dagvadorj J, Koide N, Naiki Y, Mori I, Yoshida T, Yokochi T
    Biochem. Biophys. Res. Commun., 2007;360(2):346-51.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  325. Hematopoietic stem cell-targeted neonatal gene therapy reverses lethally progressive osteopetrosis in oc/oc mice.
    Authors: Johansson MK, de Vries TJ, Schoenmaker T, Ehinger M, Brun AC, Fasth A, Karlsson S, Everts V, Richter J
    Blood, 2007;109(12):5178-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  326. The Fas/Fas ligand system inhibits differentiation of murine osteoblasts but has a limited role in osteoblast and osteoclast apoptosis.
    Authors: Kovacic N, Lukic IK, Grcevic D, Katavic V, Croucher P, Marusic A
    J. Immunol., 2007;178(6):3379-89.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  327. Bone marrow-derived cells require a functional glucose 6-phosphate transporter for normal myeloid functions.
    Authors: Kim SY, Nguyen AD, Gao JL, Murphy PM, Mansfield BC, Chou JY
    J. Biol. Chem., 2006;281(39):28794-801.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  328. Glucocorticoids act directly on osteoclasts to increase their life span and reduce bone density.
    Authors: Jia D, O'Brien CA, Stewart SA, Manolagas SC, Weinstein RS
    Endocrinology, 2006;147(12):5592-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  329. Inhibition of prostate tumor growth and bone remodeling by the vascular targeting agent VEGF121/rGel.
    Authors: Mohamedali KA, Poblenz AT, Sikes CR, Navone NM, Thorpe PE, Darnay BG, Rosenblum MG
    Cancer Res., 2006;66(22):10919-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  330. Gingival fibroblasts are better at inhibiting osteoclast formation than periodontal ligament fibroblasts.
    Authors: de Vries TJ, Schoenmaker T, Wattanaroonwong N, van den Hoonaard M, Nieuwenhuijse A, Beertsen W, Everts V
    J. Cell. Biochem., 2006;98(2):370-82.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  331. Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.
    Authors: Conway JG, Conway&lt;/LastName&gt;&lt;ForeNam JG&lt;/Initia, McDonald B, Parham J, Keith B, Rusnak DW, Shaw E, Jansen M, Lin P, Payne A, Crosby RM, Johnson JH, Frick L, Lin MH, Depee S, Tadepalli S, Votta B, James I, Fuller K, Chambers TJ, Kull FC, Chamberlain SD, Hutchins JT
    Proc. Natl. Acad. Sci. U.S.A., 2005;102(44):16078-83.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  332. Development of a culture system that supports adult microglial cell proliferation and maintenance in the resting state.
    Authors: Ponomarev ED, Novikova M, Maresz K, Shriver LP, Dittel BN
    J. Immunol. Methods, 2005;300(1):32-46.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  333. Syk is required for monocyte/macrophage chemotaxis to CX3CL1 (Fractalkine).
    Authors: Gevrey JC, Isaac BM, Cox D
    J. Immunol., 2005;175(6):3737-45.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  334. IFN-alpha priming results in a gain of proinflammatory function by IL-10: implications for systemic lupus erythematosus pathogenesis.
    Authors: Sharif MN, Tassiulas I, Hu Y, Mecklenbrauker I, Tarakhovsky A, Ivashkiv LB
    J. Immunol., 2004;172(10):6476-81.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  335. Minimally modified LDL binds to CD14, induces macrophage spreading via TLR4/MD-2, and inhibits phagocytosis of apoptotic cells.
    Authors: Miller YI, Viriyakosol S, Binder CJ, Feramisco JR, Kirkland TN, Witztum JL
    J. Biol. Chem., 2002;278(3):1561-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  336. Pneumolysin binds to the mannose receptor C type 1 (MRC-1) leading to anti-inflammatory responses and enhanced pneumococcal survival.
    Authors: Subramanian K, Neill D, Malak H, Spelmink L, Khandaker S, Dalla Libera Marchiori G, Dearing E, Kirby A, Yang M, Achour A, Nilvebrant J, Nygren P, Plant L, Kadioglu A, Henriques-Normark B
    Nat Microbiol, 0;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay

FAQs

  1. How long will recombinant mouse M-CSF last in cell culture?

    • End-users will need to determine the appropriate concentration and timing when adding Recombinant Mouse M-CSF Proteins to cell culturing experiments. The addition of protein may be dependent on certain culture conditions, including the cell number, density, and media content. For techniques and methodologies, we recommend reviewing our list of publications under the Citations tab on the product-specific web page to find reported use of our products in similar experimental layouts.

View all Proteins and Enzyme FAQs

Reviews for Recombinant Mouse M-CSF Protein

Average Rating: 4.6 (Based on 14 Reviews)

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Recombinant Mouse M-CSF Protein
By Anonymous on 04/17/2020
Application: CellProlif

Recombinant Mouse M-CSF Protein
By Anonymous on 11/15/2019
Application: Stem/Immune cell maintenance or differentiation

Recombinant Mouse M-CSF Protein
By Anonymous on 06/10/2019
Application: In vitro bioactivity in cell culture

Microglia were isolated from adult mice and kept in culture. Medium was supplemented with 10ng/ml M-CSF and it refreshed after 3 days.


Recombinant Mouse M-CSF Protein
By Anonymous on 01/09/2019
Application: In vitro bioactivity in cell culture
Reason for Rating: We used this in bone marrow macrophages to induce osteoblast. It works great cells can easily been seen under a scope. We later ran TRAP staining

Plate cells 5X10^6 on 10cm dishes. After 3 hours change media to 60 ng/ml MSCF.


Recombinant Mouse M-CSF Protein
By Anonymous on 11/20/2018
Application: Cell migration/motility
Reason for Rating: The cells migrated well attracted by the M-CSF

Recombinant Mouse M-CSF Protein
By Anonymous on 11/02/2017
Application: Other
Reason for Rating: We use this to induce the bone derived macrophage from mouse. It worked well in a relatively low concentration.

Recombinant Mouse M-CSF Protein
By Anonymous on 10/20/2017
Application: We used it to stimulate the monocyte in bone marrow of mice into macrophage.
Reason for Rating: Due to the tight budget plan, we used the M-CFS as a relatively low concentration as 10ng/ml. But it works well.

bone marrow was flushed from femurs, and tibias and resuspended in bone marrow C-BMDM(10% FBS+1% penicillin/streptomycin , 10ng/ml recombinant mouse M-CSF).


Recombinant Mouse M-CSF Protein
By Anonymous on 07/20/2017
Application: Media additive for protein or antibody production

Recombinant Mouse M-CSF Protein
By Anonymous on 02/01/2017
Application: In vivo study

Recombinant Mouse M-CSF Protein
By Anonymous on 07/21/2016
Application: Osteoclast differentiation assay

Recombinant Mouse M-CSF Protein
By Anonymous on 05/24/2016
Application: SDS-PAGE Control

Recombinant Mouse M-CSF Protein
By Anonymous on 05/16/2016
Application: Stem/Immune cell maintenance or differentiation
Reason for Rating: Worked as expected

Recombinant Mouse M-CSF Protein
By Anonymous on 05/16/2016
Application: Media additive for protein or antibody production

Recombinant Mouse M-CSF Protein
By Anonymous on 01/18/2016
Application: Stem/Immune cell maintenance or differentiation