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11 results for "Adrenergic Transporter Inhibitors Small Molecules and Peptides" in Products

Adrenergic Transporter Inhibitors Small Molecules and Peptides

Adrenergic transporters (NET) are sodium- and chloride-dependent members of the solute carrier family 6 (SLC6) widely distributed throughout the brain within noradrenergic neuronal plasma membranes. They are responsible for the re-uptake of adrenalin, noradrenalin and (to a lesser extent) dopamine from the synaptic cleft back into vesicles for storage until later use, resulting in the termination of neurotransmitter action.

Adrenergic transporters contain the following structural motifs: 12-TM domains, extracellular loops, cytoplasmic C- and N-termini and putative phosphorylation sites. A role for NETs has been proposed in attention deficit disorder, substance abuse, neurodegenerative disorders and clinical depression.

Potent noradrenalin and dopamine uptake inhibitor. Antidepressant

Chemical Name: 1,2,3,4-Tetrahydro-2-methyl-4-phenyl-8-isoquinolinamine maleate
Purity: ≥98%
Potent noradrenalin and dopamine uptake inhibitor. Antidepressant
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Selective inhibitor of noradrenalin transporters

Chemical Name: 10-11-Dihydro-N-methyl-5H-dibenz(Z)[b,f]azepine-5-propanamine hydrochloride
Purity: ≥98%
Selective inhibitor of noradrenalin transporters
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Noradrenalin re-uptake inhibitor

Chemical Name: (±)-γ-(2-Methoxyphenoxy)-N-methylbenzenepropanamine hydrochloride
Purity: ≥98%
Noradrenalin re-uptake inhibitor
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Potent and selective noradrenalin re-uptake inhibitor

Alternate Names: Atomoxetine,LY 139603
Chemical Name: (R)-N-Methyl-γ-(2-methylphenoxy)-benzenepropanamine hydrochloride
Purity: ≥98%
Potent and selective noradrenalin re-uptake inhibitor
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Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake

Alternate Names: Lu 19-005
Chemical Name: (1R,3S)-rel-3-(3,4-Dichlorophenyl)-2,3-dihydro-N-methyl-1H-inden-1-amine hydrochloride
Purity: ≥98%
Potent 5-HT uptake inhibitor; also inhibits dopamine and noradrenalin uptake
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Potent and selective noradrenalin uptake inhibitor; orally active

Chemical Name: (2R*)-2-[(R*)-(2-Ethoxyphenoxy)phenylmethyl]morpholine mesylate
Purity: ≥98%
Potent and selective noradrenalin uptake inhibitor; orally active
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Potent inhibitor of vesicular monoamine transport

Chemical Name: (3R,11bR)-rel-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-3-(2-methylpropyl)-2H-benzo[a]quinolizin-2-one
Purity: ≥98%
Potent inhibitor of vesicular monoamine transport
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Non-selective inhibitor of dopamine and noradrenalin transporters

Chemical Name: 1-(3-Chlorophenyl)-2-[(1,1-dimethylethyl)amino]-1-propanone hydrochloride
Purity: ≥98%
Non-selective inhibitor of dopamine and noradrenalin transporters
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5-HT and NA reuptake inhibitor (SNRI)

Alternate Names: Wy 45030
Chemical Name: 1-[2-(Dimethylamino)-1-(4-methoxyphenyl)ethyl]cyclohexanol hydrochloride
Purity: ≥98%
5-HT and NA reuptake inhibitor (SNRI)
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Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake

Chemical Name: (+)-(S)-N-Methyl-3-(1-naphthyloxy)-3-(2-thienyl)propanamine hydrochloride
Purity: ≥98%
Potent 5-HT and NA reuptake inhibitor (SNRI); also blocks dopamine reuptake
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Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment

Chemical Name: 5-(3-Dimethylaminopropyl)-10,11-dihydro-5H-dibenz[b,f]azepine hydrochloride
Purity: ≥98%
Potent inhibitor of 5-HT and noradrenalin transporters; promotes immunostimulatory tumor microenvironment
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