10 results for "Antifungal Compounds" in Products
Antifungal Compounds
Antimycotic Mechanism of Action
The majority of antimycotic compounds, including the azole antifungals such as Fluconazole, the polyene antibiotics such as Amphotericin B, and the allylamine, Terbinafine, exert their effects via disruption of the fungal cell membrane. Azoles are inhibitors of sterol 14α-demethylase, a fungal cytochrome P450 (CYP)-dependent enzyme, which results in depletion of cell membrane ergosterol and impaired membrane fluidity, leading to accumulation of toxic ...
Inhibitor of protein synthesis
| Chemical Name: | 4-[2-(3,5-Dimethyl-2-oxo-cyclohexyl)-2-hydroxyethyl]-2,6-piperidinedione |
| Purity: | ≥97% |
Adenosine analog; antifungal antibiotic
| Chemical Name: | 4-Amino-7-β-D-ribofuranosyl-7H-pyrrolo[2,3-d]pyrimidine-5-carbonitrile |
| Purity: | ≥98% |
Fluorescent cholesterol stain, also polyene antibiotic. Used for: Fluorescent cholesterol stain. Binds sterol in fungal membranes. Application: confocal microscopy
| Chemical Name: | (3R,4S,6S,8S,10R,12R,14R,16S,17E,19E,21E,23E,25E,27S,28R)-4,6,8,10,12,14,16,27-Octahydroxy-3-[(1R)-1-hydroxyhexyl]-17,28-dimethyloxacyclooctacosa-17,19,21,23,25-pentaen-2-one |
| Purity: | ≥90% |
Pan-histone demethylase inhibitor
| Chemical Name: | 6-Cyclohexyl-1-hydroxy-4-methyl-2(1H)-pyridinone |
| Purity: | ≥98% |
Triazole antifungal agent
| Alternate Names: | UK 49858 |
| Chemical Name: | 2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-1-yl)propan-2-ol |
Cytochrome P450 inhibitor; antifungal
| Alternate Names: | CLT |
| Chemical Name: | 1-(2-Chloro-α,α-diphenylbenzyl)imidazole |
| Purity: | ≥98% |
SMO antagonist; acts at different binding site to cyclopamine (Cat No. 1623)
| Chemical Name: | 4-[4-[4-[4-[[2-(2,4-Dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-yl]methoxy]phenyl]-1-piperazinyl]phenyl]-2,4-dihydro-2-(1-methylpropyl)-3H-1,2,4-triazol-3-one |
| Purity: | ≥98% |
Selective K2P9.1 (TASK-3) activator; also inhibits fungal squalene epoxidase
| Chemical Name: | N-[(2E)-6,6-Dimethyl-2-hepten-4-yn-1-yl]-N-methyl-1-naphthalenemethanamine hydrochloride |
| Purity: | ≥98% |
Forms monovalent ion channels in lipid bilyers; antifungal
| Chemical Name: | (1R,3S,5R,6R,9R,11R,15S,16R,17R,18S,19E,21E,23E,25E,27E,29E,31E,33R,35S,36R,37S)-33-[(3-Amino-3,6-dideoxy-β-D-mannopyranosyl)oxy]-1,3,5,6,9,11,17,37-octahydroxy-15,16,18-trimethyl-13-oxo-14,39-dioxabicyclo[33.3.1]nonatriaconta-19,21,23,25,27,29,31-heptaene-36-carboxylic acid |
| Purity: | ≥90% |
5-HT reuptake inhibitor
| Chemical Name: | (1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-N-methyl-1-naphthalenamine hydrochloride |
| Purity: | ≥98% |
