Search for cell-cycle-inhibitors&view=expanded

Chemical Name:	(4R,7R,8S,9E,11S,12S)-8-(Acetyloxy)-4,7-dihydroxy-12-[(1E,3E,5S)-6-[(2R,3R)-3-[(1R,2S)-2-hydroxy-1-methylbutyl]-2-oxiranyl]-1,5-dimethyl-1,3-hexadien-1-yl]-7,11-dimethyloxacyclododec-9-en-2-one
Purity:	≥95%

Catalog #: 1230

Cytotoxic agent

Chemical Name:	N-[4-[[(2,4-Diamino-6-pteridinyl)methyl]methylamino]benzoyl]-L-glutamic acid
Purity:	≥98%

Catalog #: 5493

Potent and selective Cdc7 inhibitor

Alternate Names:	BMS 863233
Chemical Name:	8-Chloro-2-(2S)-2-pyrrolidinylbenzofuro[3,2-d]pyrimidin-4(3H)-one hydrochloride
Purity:	≥98%

Catalog #: 7157

Potent and selective CDK7 inhibitor; induces cell cycle arrest

Chemical Name:	N-[(1S)-2-(Dimethylamino)-1-phenylethyl]-4,6-dihydro-6,6-dimethyl-3-[[4-[(1-oxo-2-propen-1-yl)amino]benzoyl]amino]pyrrolo[3,4-c]pyrazole-5(1H)-carboxamide
Purity:	≥95%

Catalog #: 4406

(1)

Inhibits c-Myc-Max dimerization

Chemical Name:	5-[(4-Ethylphenyl)methylene]-2-thioxo-4-thiazolidinone
Purity:	≥98%

Catalog #: 7680

(1)

High affinity Bcl-2 family inhibitor; proapoptotic, senolytic and antitumor

Chemical Name:	4-[4-[[2-(4-Chlorophenyl)-5,5-dimethyl-1-cyclohexen-1-yl]methyl]-1-piperazinyl]-N-[[4-[[(1R)-3-(4-morpholinyl)-1-[(phenylthio)methyl]propyl]amino]-3-[(trifluoromethyl)sulfonyl]phenyl]sulfonyl]benzamide
Purity:	≥98%

Catalog #: 5331

(1)

BET bromodomain inhibitor; arrests cell cycle at G1 phase

Alternate Names:	TEN 010
Chemical Name:	(6S)-4-(4-Chlorophenyl)-2,3,9-trimethyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine-6-acetamide
Purity:	≥98%

Catalog #: 4282

Potent and selective mTOR inhibitor

Chemical Name:	N-[4-[4-(4-Morpholinyl)-1-[1-(3-pyridinylmethyl)-4-piperidinyl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]phenyl]-carbamic acid methyl ester dihydrochloride
Purity:	≥98%