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15 results for "compounds-for-hsc-proliferation-and-renewal&view=expanded" in Products

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

GMP Version Available: TB1614-GMP
GMP
Chemical Name: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity: ≥99%
dopaminergic neurons derived from hiPSCs using SB 431542
(2)
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Highly selective GSK-3 inhibitor; acts as Wnt activator

GMP Version Available: TB4423-GMP
GMP
Alternate Names: CHIR99021,CT99021
Chemical Name: 6-[[2-[[4-(2,4-Dichlorophenyl)-5-(5-methyl-1H-imidazol-2-yl)-2-pyrimidinyl]amino]ethyl]amino]-3-pyridinecarbonitrile
Purity: ≥98%
Cardiomyocyte derived from human induced pluripotent stem cells (hiPSCs) using CHIR 99021.
(2)
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Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin

Alternate Names: PGE2
Chemical Name: (5Z,11α,13E,15S)-11,15-Dihydroxy-9-oxo-prosta-5,13-dien-1-oic acid
Purity: ≥98%
Promotes HSCs expansion; increases HSCs engraftment; also endogenous prostaglandin
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Selective inhibitor of p38 MAPK

Alternate Names: Adezmapimod
Chemical Name: 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine
Purity: ≥98%
Selective inhibitor of p38 MAPK
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Potent GSK-3 inhibitor; also inhibits cdks

Alternate Names: 6BIO
Chemical Name: (2'Z,3'E)-6-Bromoindirubin-3'-oxime
Purity: ≥98%
Potent GSK-3 inhibitor; also inhibits cdks
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Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development

Chemical Name: (5Z,11α,13E,15R)-11,15-Dihydroxy-16,16-dimethyl-9-oxo-prosta-5,13-dien-1oic acid
Purity: ≥95%
Synthetic prostaglandin E2 (Cat. No. 2296) derivative; regulates HSC development
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Potent integrin inhibitor (αvβ3/αvβ6); also improves stem cell attachment in 3D cell culture scaffolds

Purity: ≥95%
Potent integrin inhibitor (αVβ3/αVβ5); also improves stem cell attachment in 3D cell culture scaffolds
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Glutathione (GSH) precursor; neuroprotective

Chemical Name: (2R)-2-(Acetylamino)-3-mercaptopropanamide
Glutathione (GSH) precursor; neuroprotective
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Selective PPARγ agonist; antidiabetic agent

Alternate Names: Rezulin
Chemical Name: 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione
Purity: ≥98%
Selective PPARγ agonist; antidiabetic agent
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PARP-1 inhibitor

Chemical Name: Pyridine-3-carboxamide
Purity: ≥99%
iPSC-derived Human Intestinal Organoid
(5)
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