10 results for "Cytokine Compounds" in Products
Cytokine Compounds
Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases.
Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune ...
Binds cereblon; also TNF-α synthesis inhibitor
| Chemical Name: | N-(2,6-dioxo-3-piperidinyl)phthalimide |
| Purity: | ≥98% |
Macrophage migration inhibitory factor (MIF) inhibitor
| Chemical Name: | 4,5-Dihydro-3-(4-hydroxyphenyl)-5-isoxazoleacetic acid methyl ester |
| Purity: | ≥98% |
gp130 inhibitor; blocks cytokine-triggered gp130 signaling
| Chemical Name: | 2-(7-Fluoropyrrolo[1,2-a]quinoxalin-4-yl) 2-pyrazinecarboxylic acid hydrazide hydrochloride |
| Purity: | ≥98% |
Selective Syk kinase inhibitor
| Chemical Name: | 10-(3-Aminopropyl)-3,4-dimethyl-9(10H)-acridinone maleate |
| Purity: | ≥98% |
Serine protease inhibitor; inhibits thrombin, trypsin, kallikrein and plasmin
| Alternate Names: | FOY |
| Chemical Name: | 4-[[6-[(Aminoiminomethyl)amino]-1-oxohexyl]oxy]-benzoic acid ethyl ester mesylate |
| Purity: | ≥98% |
Potent and selective IRAK4 inhibitor
| Chemical Name: | N-[3-Aminocarbonyl)-1-(tetrahydro-2H-pyran-4-yl)-1H-pyrazol-4-yl]-2-(2-methyl-4-pyridinyl)-4-oxazolecarboxamide hydrochloride |
| Purity: | ≥98% |
NLRP3 inflammasome inhibitor
| Alternate Names: | JC121 |
| Chemical Name: | N-[2-[4-(Aminosulfonyl)phenyl]ethyl]-5-chloro-2-methoxybenzamide |
| Purity: | ≥98% |
TIR-TIR interaction inhibitor
| Chemical Name: | 1-Methyl-2,5-bis[[[(1S)-2-methyl-1-(1-pyrrolidinylcarbonyl)propyl](3-phenylpropyl)amino]carbonyl]pyridinium iodide |
| Purity: | ≥98% |
TRAF6-Ubc13 interaction inhibitor
| Chemical Name: | 3-[3,5-Dimethyl-1-(3-methyl-1,2,4-triazolo[4,3-b]pyridazin-6-yl)-1H-pyrazol-4-yl]-1-[4-(phenylmethyl)-1-piperidinyl]-1-propanone |
| Purity: | ≥98% |
Potent NLRP3 inflammasome inhibitor
| Chemical Name: | 2-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)amino)-5-(pyridin-2-ylmethyl)-[1,2,4]triazolo[1,5-a]pyrimidine-7(4H)-thione |
| Purity: | ≥95% |
