9 results for "Cytokine Compounds" in Products

Cytokine Compounds

Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases.

Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune ...

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Antifibrotic agent; regulates cytokine levels in vivo

Chemical Name: 5-methyl-1-phenyl-2(1H)-pyridinone
Purity: ≥98%
Antifibrotic agent; regulates cytokine levels in vivo
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Suppressor of MDK expression; inhibits PI 3-K signaling

Chemical Name: 3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one
Purity: ≥98%
Suppressor of MDK expression; inhibits PI 3-K signaling
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Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase

Chemical Name: 3-(4-Amino-1,3-dihydro-1-oxo-2H-isoindol-2-yl)-2,6-piperidinedione
Purity: ≥98%
Cereblon binder; induces ubiquitination and degradation of CK1α by E3 ubiquitin ligase
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Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate

Chemical Name: 4-Iodo-6-phenylpyrimidine
Purity: ≥98%
Inhibitor of macrophage migration inhibitory factor (MIF); suicide substrate
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Cereblon binder; also TNF-α inhibitor and antiangiogenic

Chemical Name: 4-Amino-2-(2,6-dioxo-3-piperidinyl)-1H-isoindole-1,3(2H)-dione
Purity: ≥98%
Cereblon binder; also TNF-α inhibitor and antiangiogenic
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Immunomodulator; reduces production of pro-inflammatory cytokines

Chemical Name: 4,5-Dihydro-3-phenyl-5-isoxazoleacetic acid
Purity: ≥98%
Immunomodulator; reduces production of pro-inflammatory cytokines
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MIF binder

Chemical Name: 2-(2-Pyridinyl)-4H-1,3-benzothiazin-4-one
Purity: ≥98%
MIF binder
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Immunomodulatory and antitumor compound

Chemical Name: 2-Amino-5-bromo-6-phenyl-4(3H)-pyrimidone
Purity: ≥98%
Immunomodulatory and antitumor compound
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Active metabolite binds CPSF3; Pro-drug

Alternate Names: TO-207
Chemical Name: N-[3,5-Dichloro-2-hydroxy-4-[2-(4-methyl-1-piperazinyl)ethoxy]benzoyl]-L-phenylalanine ethyl ester dihydrochloride
Purity: ≥98%
Active metabolite binds CPSF3; Pro-drug
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