8 results for "GABA-B R1" in Products
GABA-B R1 Products
The neurotransmitter gamma-aminobutyric acid (GABA) mediates an inhibitory signal upon binding to two ligand-gated channels, GABA-A and GABA-C receptors, and a G protein-coupled receptor (GPCR), GABA-B. The GABA-B receptor is a heterodimeric complex composed of two 7-transmembrane GPCRs termed GABA-B R1 and GABA-B R2. GABA-B receptors have been implicated in the GABA-induced modulation of sympathetic and catecholaminergic pathways in the central nervous system.
Potent and selective GABAB antagonist
| Chemical Name: | (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinic acid hydrochloride |
| Purity: | ≥98% |
Potent and selective GABAB antagonist
| Chemical Name: | [S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl) phosphinic acid |
| Purity: | ≥96% |
Selective GABAB antagonist
| Chemical Name: | (RS)-3-Amino-2-(4-chlorophenyl)propylsulfonic acid |
| Purity: | ≥98% |
Selective GABAB antagonist; more potent than Saclofen (Cat. No. 0246)
| Chemical Name: | (RS)-3-Amino-2-(4-chlorophenyl)-2-hydroxypropyl-sulfonic acid |
Selective and competitive GABAB antagonist; orally bioavailable
| Chemical Name: | (2S)-(+)-5,5-Dimethyl-2-morpholineacetic acid |
| Purity: | ≥98% |
Selective GABAB antagonist; brain penetrant
| Chemical Name: | (3-Aminopropyl)(diethoxymethyl)phosphinic acid |
Potent and selective GABAB antagonist
| Chemical Name: | 3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid |
| Purity: | ≥98% |
GABAB antagonist; displays activity at presynaptic receptors
| Chemical Name: | (3-Aminopropyl)ethylphosphinic acid hydrochloride |
| Purity: | ≥98% |
