163 results for "GABA-B R1" in Products
GABA-B R1 Products
The neurotransmitter gamma-aminobutyric acid (GABA) mediates an inhibitory signal upon binding to two ligand-gated channels, GABA-A and GABA-C receptors, and a G protein-coupled receptor (GPCR), GABA-B. The GABA-B receptor is a heterodimeric complex composed of two 7-transmembrane GPCRs termed GABA-B R1 and GABA-B R2. GABA-B receptors have been implicated in the GABA-induced modulation of sympathetic and catecholaminergic pathways in the central nervous system.
Potent and selective GABAB antagonist
| Chemical Name: | (2S)-3-[[(1S)-1-(3,4-Dichlorophenyl)ethyl]amino-2-hydroxypropyl](phenylmethyl)phosphinic acid hydrochloride |
| Purity: | ≥98% |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG2a Kappa Monoclonal Clone #2D7 |
| Applications: | IHC, WB, ELISA, ICC/IF, Mycoplasma |
![Western Blot: GABA-B R1 Antibody (2D7) [H00002550-M01]](https://resources.rndsystems.com/images/products/GABA-B-R1-Antibody-2D7-Western-Blot-H00002550-M01-img0016.jpg "Western Blot: GABA-B R1 Antibody (2D7) [H00002550-M01]")
| Reactivity: | Human, Mouse, Rat |
| Details: | Sheep IgG Polyclonal |
| Applications: | IHC, WB |
Selective GABAB agonist; active enantiomer of (RS)-Baclofen (Cat. No. 0417)
| Alternate Names: | STX 209 |
| Chemical Name: | (R)-4-Amino-3-(4-chlorophenyl)butanoic acid |
| Purity: | ≥99% |
Potent and selective GABAB antagonist
| Chemical Name: | [S-(R*,R*)]-[3-[[1-(3,4-Dichlorophenyl)ethyl]amino]-2-hydroxypropyl](cyclohexylmethyl) phosphinic acid |
| Purity: | ≥96% |
Selective GABAB antagonist
| Chemical Name: | (RS)-3-Amino-2-(4-chlorophenyl)propylsulfonic acid |
| Purity: | ≥98% |
Selective GABAB antagonist; more potent than Saclofen (Cat. No. 0246)
| Chemical Name: | (RS)-3-Amino-2-(4-chlorophenyl)-2-hydroxypropyl-sulfonic acid |
Selective and competitive GABAB antagonist; orally bioavailable
| Chemical Name: | (2S)-(+)-5,5-Dimethyl-2-morpholineacetic acid |
| Purity: | ≥98% |
| Reactivity: | Rat |
| Details: | Mouse IgG2A Monoclonal Clone #751216 |
| Applications: | IHC |
Selective GABAB antagonist; brain penetrant
| Chemical Name: | (3-Aminopropyl)(diethoxymethyl)phosphinic acid |
Potent and selective GABAB antagonist
| Chemical Name: | 3-[[(3,4-Dichlorophenyl)methyl]amino]propyl] diethoxymethyl)phosphinic acid |
| Purity: | ≥98% |
Caged GABA; inhibits neural activity
| Alternate Names: | RuBi-GABA-PMe3 |
| Chemical Name: | (bis(2,2'-Bipyridine-N,N')trimethylphosphine)-4-aminobutyric acid ruthenium complex sodium hexafluorophosphate salt |
| Reactivity: | Human, Mouse, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #S93A-49 |
| Applications: | WB, ICC/IF |
![Western Blot: GABA-B R1 Antibody (S93A-49) [NBP2-59336]](https://resources.rndsystems.com/images/products/GABA-B-R1-Antibody-S93A-49-Western-Blot-NBP2-59336-img0005.jpg "Western Blot: GABA-B R1 Antibody (S93A-49) [NBP2-59336]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #PSH03-87 |
| Applications: | IHC, WB |
| Reactivity: | Human, Mouse, Rat, Porcine, Bat, +7 More |
| Details: | Goat IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: GABA-B R1 Antibody [NBP1-52389]](https://resources.rndsystems.com/images/products/GABA-B-R1-Antibody-Immunohistochemistry-Paraffin-NBP1-52389-img0002.jpg "Immunohistochemistry-Paraffin: GABA-B R1 Antibody [NBP1-52389]")
| Reactivity: | Human, Mouse, Rat, Porcine, Bat, +6 More |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
![Immunohistochemistry-Paraffin: GABA-B R1 Antibody - BSA Free [NLS5332]](https://resources.rndsystems.com/images/products/GABA-B-R1-Antibody-Immunohistochemistry-Paraffin-NLS5332-img0003.jpg "Immunohistochemistry-Paraffin: GABA-B R1 Antibody - BSA Free [NLS5332]")
Highly potent GABAB agonist; also GABAA-ρ antagonist
| Alternate Names: | CGP 35024 |
| Chemical Name: | 3-Aminopropyl(methyl)phosphinic acid |
Selective GABAB agonist
| Chemical Name: | (RS)-4-Amino-3-(4-chlorophenyl)butanoic acid |
| Purity: | ≥99% |
Positive allosteric modulator of GABAB receptors
| Chemical Name: | 3,5-bis(1,1-Dimethylethyl)-4-hydroxy-β,β-dimethyl-benzenepropanol |
| Purity: | ≥98% |
Positive allosteric modulator of GABAB receptors
| Chemical Name: | N,N'-Dicyclopentyl-2-(methylthio)-5-nitro-4,6-pyrimidinediamine |
| Purity: | ≥98% |
GABAB antagonist; displays activity at presynaptic receptors
| Chemical Name: | (3-Aminopropyl)ethylphosphinic acid hydrochloride |
| Purity: | ≥98% |
Potent and selective postitive allosteric modulator of GABAB receptors
| Chemical Name: | 5,7-Bis(1,1-dimethylethyl)-3-hydroxy-3(trifluoromethyl)-2(3H)-benzofuranone |
| Purity: | ≥98% |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: GABA-B R1 AntibodyBSA Free [NB300-160]](https://resources.rndsystems.com/images/products/GABA-B-R1-Antibody-Western-Blot-NB300-160-img0003.jpg "Western Blot: GABA-B R1 AntibodyBSA Free [NB300-160]")
| Reactivity: | Human |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #JE60-09 |
| Applications: | IHC, WB |
