10 results for "Glutamate (EAAT) Transporter Inhibitors Small Molecules and Peptides" in Products
Glutamate (EAAT) Transporter Inhibitors Small Molecules and Peptides
Glutamate transporters, also known as excitatory amino acid transporters (EAATs), are sodium- and potassium-dependent members of the solute carrier family 6 (SLC1) found widely distributed throughout the brain. There are five EAAT subtypes, each with a specific primary distribution; EAAT1 (cerebellar glia), EAAT2 (forebrain glia), EAAT3 (cortical neurons), EAAT4 (cerebellar Purkinje neurons) and EAAT5 (retina).
Functions of glutamate transporters include regulation of excitatory neurotransmission...
Selective non-transportable inhibitor of EAATs
| Chemical Name: | DL-threo-β-Benzyloxyaspartic acid |
| Purity: | ≥98% |
Potent and selective EAAT1 and EAAT2 blocker
| Chemical Name: | (3S)-3-[[3-[[4-(Trifluoromethyl)benzoyl]amino]phenyl]methoxy]-L-aspartic acid |
| Purity: | ≥98% |
EAAT2 (GLT-1)-selective non-transportable inhibitor of L-glutamate and L-aspartate uptake
| Chemical Name: | (2S,3S,4R)-2-Carboxy-4-isopropyl-3-pyrrolidineacetic acid |
Potent competitive inhibitor of L-glutamate uptake
| Chemical Name: | 7-Chloro-4-hydroxyquinoline-2-carboxylic acid |
| Purity: | ≥98% |
Dye for assessing cell viability and blood brain barrier permeability; also EAAT inhibitor and iGluR antagonist
| Chemical Name: | 6,6-[(3,3'-Dimethyl[1,1'-biphenyl]-4,4'-diyl)bis(azo)bis[4-amino- 5-hydroxy-1,3-naphthalenedisulphonic acid] tetrasodium salt |
| Purity: | ≥90% |
Selective non-substrate EAAT1 inhibitor
| Chemical Name: | 2-Amino-5,6,7,8-tetrahydro-4-(4-methoxyphenyl)-7-(naphthalen-1-yl)-5-oxo-4H-chromene-3-carbonitrile |
| Purity: | ≥98% |
Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor
| Alternate Names: | L-threo-β-Hydroxyaspartic acid |
| Purity: | ≥98% |
Transportable EAAT1-4 inhibitor/non-transportable EAAT5 inhibitor
| Alternate Names: | trans-4-Carboxy-L-proline |
| Chemical Name: | L-trans-Pyrrolidine-2,4-dicarboxylic acid |
| Purity: | ≥97% |
Potent, non-substrate EAAT2 inhibitor
| Chemical Name: | N-[4-(2-Bromo-4,5-difluorophenoxy)phenyl]-L-asparagine |
| Purity: | ≥98% |
Potent competitive inhibitor of L-glutamate uptake. Sodium salt of 7-Chlorokynurenic acid (Cat. No. 0237)
| Chemical Name: | 7-Chloro-4-hydroxyquinoline-2-carboxylic acid sodium salt |
| Purity: | ≥98% |
