83 results for "HMG-CoA Reductase/HMGCR" in Products
HMG-CoA Reductase/HMGCR Products
HMG-CoA reductase is the rate-limiting enzyme for cholesterol synthesis and is regulated via a negative feedback mechanism mediated by sterols and non-sterol metabolites derived from mevalonate, the product of the reaction catalyzed by reductase. Normally in mammalian cells this enzyme is suppressed by cholesterol derived from the internalization and degradation of low density lipoprotein (LDL) via the LDL receptor. Competitive inhibitors of the reductase induce the expression of LDL receptors ...
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #JF0981 |
| Applications: | IHC, WB, Simple Western, IP |
![Western Blot: HMG-CoA Reductase/HMGCR Antibody (JF0981) [NBP2-66888]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-JF0981-Western-Blot-NBP2-66888-img0003.jpg "Western Blot: HMG-CoA Reductase/HMGCR Antibody (JF0981) [NBP2-66888]")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL0259 |
| Applications: | IHC, WB, Mycoplasma |
![Western Blot: HMG-CoA Reductase/HMGCR Antibody (CL0259) [NBP2-61616]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-CL0259-Western-Blot-NBP2-61616-img0001.jpg "Western Blot: HMG-CoA Reductase/HMGCR Antibody (CL0259) [NBP2-61616]")
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC, ICC/IF |
![Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP1-91996]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-Immunohistochemistry-Paraffin-NBP1-91996-img0008.jpg "Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP1-91996]")
Inhibits hepatitis C viral life cycle; also α-crystallin (cryAB) chaperone
| Chemical Name: | Cholest-5-ene-3β,25-diol |
| Purity: | ≥95% |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0260 |
| Applications: | IHC, WB, Mycoplasma |
![Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-CL0260-Immunohistochemistry-Paraffin-NBP2-61617-img0010.jpg "Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP2-61617]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL0259 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0259) Immunohistochemistry: HMG-CoA Reductase/HMGCR Antibody (CL0259) [NBP3-52097]](https://resources.rndsystems.com/images/products/nbp3-52097_mouse-hmg-coa-reductase-hmgcr-mab-cl0259-immunohistochemistry-27320261519624.jpg "Immunohistochemistry: HMG-CoA Reductase/HMGCR Antibody (CL0259) [NBP3-52097]")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL0259 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0259) - Azide and BSA Free Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP3-43943]](https://resources.rndsystems.com/images/products/nbp3-43943_mouse-hmg-coa-reductase-hmgcr-mab-cl0259-azide-bsa-free-282202512195421.jpg "Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP3-43943]")
Recombinant Monoclonal Antibody
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0260 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0260) Immunohistochemistry: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP3-52096]](https://resources.rndsystems.com/images/products/nbp3-52096_mouse-hmg-coa-reductase-hmgcr-mab-cl0260-immunohistochemistry-27320261526915.jpg "Immunohistochemistry: HMG-CoA Reductase/HMGCR Antibody (CL0260) [NBP3-52096]")
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0260 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0260) - Azide and BSA Free Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP3-43933]](https://resources.rndsystems.com/images/products/nbp3-43933_mouse-hmg-coa-reductase-hmgcr-mab-cl0260-azide-bsa-free-282202512135869.jpg "Immunohistochemistry-Paraffin: HMG-CoA Reductase/HMGCR Antibody [NBP3-43933]")
HMG-CoA reductase inhibitor
| Chemical Name: | (1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyly-2,2-dimethyl butanoate |
| Purity: | ≥98% |
Potent HMG-CoA reductase inhibitor
| Alternate Names: | Mevinolin |
| Chemical Name: | (2S)-(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-[2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl]-1-naphthalenyl-2-methyl butanoate |
| Purity: | ≥97% |
Potent HMG-CoA reductase inhibitor
| Chemical Name: | (±)-(3R*,5S*,6E)-7-[3-(4-Fluorophenyl)-1-(1-methyethyl)-1H-indol-2-yl]-3,5-dihydroxy-6-heptenoic acid sodium salt |
| Purity: | ≥98% |
HMG-CoA reductase inhibitor
| Alternate Names: | Eptastatin sodium |
| Chemical Name: | (βR,δR,1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-β,δ,6-trihydroxy-2-methyl-8-[(2S)-2-methyl-1-oxobutoxy]-1-naphthaleneheptanoic acid monosodium salt |
| Purity: | ≥98% |
HMG-CoA reductase inhibitor
| Alternate Names: | NK-104 |
| Chemical Name: | (3R,5S,6E)-7-[2-Cyclopropyl-4-(4-fluorophenyl)-3-quinolinyl]-3,5-dihydroxy-6-heptenoic acid hemicalcium salt |
| Purity: | ≥98% |
Potent HMG-CoA reductase inhibitor
| Chemical Name: | (3R,5S,6E)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl])-3,5-dihydroxyhept-6-enoic acid hemicalcium salt |
| Purity: | ≥98% |
| Reactivity: | Human |
| Source: | E. coli |
| Accession #: | P04035 |
| Applications: | Enzyme Activity |
| Reactivity: | Human |
| Details: | Goat IgG Polyclonal |
| Applications: | ELISA, Flow, ICC/IF |
![Immunocytochemistry/ Immunofluorescence: HMG-CoA Reductase/HMGCR Antibody [NBP3-05292]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-Immunocytochemistry-Immunofluorescence-NBP3-05292-img0001.jpg "Immunocytochemistry/ Immunofluorescence: HMG-CoA Reductase/HMGCR Antibody [NBP3-05292]")
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse, Rat |
| Details: | Rabbit IgG Monoclonal Clone #6Y9L8 |
| Applications: | WB |
![Western Blot: HMG-CoA Reductase/HMGCR Antibody (6Y9L8) [NBP3-15641]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-6Y9L8-Western-Blot-NBP3-15641-img0001.jpg "Western Blot: HMG-CoA Reductase/HMGCR Antibody (6Y9L8) [NBP3-15641]")
| Reactivity: | Human |
| Applications: | WB |
![Other: HMG-CoA Reductase/HMGCR 293T Cell Transient Overexpression Lysate [H00003156-T01]](https://resources.rndsystems.com/images/products/qc_test-H00003156-T01-1.jpg "Other: HMG-CoA Reductase/HMGCR 293T Cell Transient Overexpression Lysate [H00003156-T01]")
| Reactivity: | Human |
| Sensitivity: | 0.38 ng/mL |
| Assay Range: | 0.63 - 40 ng/mL |
| Applications: | ELISA |
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Polyclonal |
| Applications: | WB |
![Western Blot: HMG-CoA Reductase/HMGCR AntibodyBSA Free [NBP3-03778]](https://resources.rndsystems.com/images/products/HMG-CoA-Reductase-HMGCR-Antibody-Western-Blot-NBP3-03778-img0002.jpg "Western Blot: HMG-CoA Reductase/HMGCR AntibodyBSA Free [NBP3-03778]")
| Reactivity: | Human |
| Source: | E. coli |
| Applications: | AC |
| Reactivity: | Rat |
| Details: | Mouse IgG1 kappa Monoclonal Clone #C2 |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #CL0260 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0260) [CoraFluor™ 1]](https://resources.rndsystems.com/images/products/nbp3-43933cl1_mouse-hmg-coa-reductase-hmgcr-mab-cl0260-corafluor-1-249202516481317.png "Product Feature: CoraFluor Probes for TR-FRET")
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #CL0259 |
| Applications: | IHC, WB |
![HMG-CoA Reductase/HMGCR Antibody (CL0259) [CoraFluor™ 1]](https://resources.rndsystems.com/images/products/nbp3-43943cl1_mouse-hmg-coa-reductase-hmgcr-mab-cl0259-corafluor-1-810202510453013.png "Product Feature: CoraFluor Probes for TR-FRET")