Klotho: Products

The Klotho proteins, Klotho and Klotho beta (beta KL), are type I transmembrane glycoproteins with extracellular regions that contain two beta-glycosidase-like repeats.

Klotho beta, a divergent structural member of the glycosidase I superfamily, is primarily expressed in the liver and pancreas, with lower expression in adipose tissue. Klotho beta mediates the interaction of FGF-15 (human FGF-19) with FGF Receptor 4 in the liver, which negatively regulates bile acid synthesis by controlling the secretion of two key bile acid synthase genes. Klotho beta is also a cofactor for the interaction of FGF-21 with FGF Receptor 1c in adipocytes. The expression pattern of Klotho beta suggests it may play a role in lipid metabolism.

"Klotho" has 8 results in Products.
Sort by:
Results Per Page:

Mouse Klotho Antibody 

3 Images
ELISA, IHC, WB

Mouse Klotho Antibody 

Human Klotho Antibody 

Recombinant Human Klotho His-tag Protein, CF 

Mucin Stalk Chimera
2 Images
Bioactivity
page of 1