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Selective NaV1.8 channel blocker
Cardiac Na+ channel blocker. Antiarrhythmic
Na+ channel blocker; antiarrhythmic agent
Antianginal, activates pyruvate dehydrogenase
Blocks voltage-sensitive Na+ and Ca2+ channels (T-type)
NaV blocker; neuroprotective
Inhibitor of neuronal NaV channels; anticonvulsant
Potent voltage-dependent NaV1.8 channel blocker
Potent and selective NaV1.8 channel blocker; active in vivo