13 results for "PPAR gamma/NR1C3 Small Molecules and Peptides" in Products

PPAR gamma/NR1C3 Small Molecules and Peptides

Peroxisome proliferator-activated receptor gamma (PPAR gamma) is a lipid-activated nuclear hormone receptor with roles in adipocyte differentiation, lipid and glucose metabolism, and modulation of immune and inflammatory reactions. PPAR gamma is the receptor for insulin-sensitizing thiazolidinediones, commonly used for the treatment of type 2 diabe...

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Potent and selective PPARγ agonist; antidiabetic agent

Alternate Names: BRL 49653
Chemical Name: 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-thiazolidinedione
Purity: ≥98%
Potent and selective PPARγ agonist; antidiabetic agent
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Selective covalent PPARγ antagonist

Chemical Name: 2-Chloro-5-nitro-N-phenylbenzamide
Purity: ≥98%
Selective covalent PPARγ antagonist
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Selective PPARγ agonist; antidiabetic agent

Chemical Name: 5-[[4-[2-(5-Ethyl-2-pyridinyl)-ethoxy]phenyl]methyl]-2,4-thiazolidinedione hydrochloride
Purity: ≥98%
Selective PPARγ agonist; antidiabetic agent
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PPARγ partial agonist

Chemical Name: 2,4-Dichloro-N-[3,5-dichloro-4-(3-quinolinyloxy)phenyl]benzenesulfonamide
Purity: ≥98%
PPARγ partial agonist
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PPARα/γ agonist

Alternate Names: AZ 242
Chemical Name: (S)-2-Ethoxy-3-[4-[2-(4-methanesulfonyloxyphenyl)ethoxy]phenyl]propanoic acid
Purity: ≥98%
PPARα/γ agonist
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Dual site PPARγ inhibitor

Chemical Name: 2-Chloro-N-(6-methoxy-4-quinolinyl)-5-nitrobenzamide
Purity: ≥98%
Dual site PPARγ inhibitor
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Highly potent and selective covalent PPARγ antagonist

Chemical Name: 2-Chloro-5-nitro-N-4-pyridinylbenzamide
Purity: ≥98%
Highly potent and selective covalent PPARγ antagonist
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Selective PPARγ agonist. Orally active

Chemical Name: N-(2-Benzoylphenyl)-O-[2-(methyl-2-pyridinylamino)ethyl]-L-tyrosine hydrochloride
Purity: ≥98%
Selective PPARγ agonist. Orally active
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EGFR kinase inhibitor. Also estrogen and PPARγ ligand

Chemical Name: 5,7-Dihydroxy-3-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
Purity: ≥98%
EGFR kinase inhibitor. Also estrogen and PPARγ ligand
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Selective PPARγ agonist; antidiabetic agent

Alternate Names: Rezulin
Chemical Name: 5-[[4-[(3,4-Dihydro-6-hydroxy-2,5,7,8-tetramethyl-2H-1-benzopyran-2-yl)methoxy]phenyl]methyl]-2,4-thiazolidinedione
Purity: ≥98%
Selective PPARγ agonist; antidiabetic agent
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Potent and selective PPARγ agonist; antidiabetic

Alternate Names: R 483,BM 131258
Chemical Name: 5-[[4-[2-(5-Methyl-2-phenyl-4-oxazolyl)ethoxy]benzo[b]thien-7-yl]methyl]-2,4-thiazolidinedione
Purity: ≥98%
Potent and selective PPARγ agonist; antidiabetic
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Nrf2 signaling activator

Chemical Name: 1-(2-Cyano-3,12,28-trioxooleana-1,9(11)-dien-28-yl)-1H-imidazole
Purity: ≥98%
Nrf2 signaling activator
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Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit

Alternate Names: Gleevec,CGP 57148B
Chemical Name: 4-[(4-Methyl-1-piperazinyl)methyl]-N-[4-methyl-3-[[4-(3-pyridinyl)-2-pyrimidinyl]amino]phenyl]benzamide methanesulfonate
Purity: ≥98%
Potent and selective v-Abl tyrosine kinase inhibitor; also inhibits PDGFR and c-kit
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