252 results for "TrkC" in Products

TrkC Products

Members of the Tyrosine Kinase Receptor (Trk) family (TrkA, TrkB, and TrkC) of receptor tyrosine kinases act as receptors for the neurotrophin family: BDNF, NGF, NT-3, and NT-4. Trks exhibit selectivity for specific neurotrophins. TrkA, TrkB and TrkC preferentially bind NGF, NT-4 and BDNF, and NT-3, respectively. All Trk family proteins share a common structural organization consisting of an extracellular region with two cysteine-rich domains, a cluster of three leucine-rich motifs, and two immunoglobulin-like domains, and an intracellular region that contains the tyrosine kinase domain. They are best known for their regulation of neuronal survival and axon outgrowth. TrkC is predominantly expressed in the central nervous system.

Contains 4 membranes - each spotted in duplicate with 49 different RTK antibodies

Reactivity: Human
Detection of Human Receptor Tyrosine Kinase Phosphorylation in KATO-III Cell Line.
(2)
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Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 Monoclonal Clone #OTI2B8
Applications: IHC, WB, ICC/IF
Western Blot: TrkC Antibody (OTI2B8) [NBP1-47900]
(11)
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Reactivity: Human, Mouse, Rat
Details: Mouse IgG1 Monoclonal Clone #OTI2B8
Applications: IHC, WB, ICC/IF
Western Blot: TrkC Antibody (OTI2B8)Azide and BSA Free [NBP2-74626]
(11)
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Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, ICC/IF
Immunocytochemistry/ Immunofluorescence: TrkC Antibody [NB100-98829]
(12)
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Reactivity: Human
Source: NS0
Accession #: Q96CY4
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
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Reactivity: Human, Mouse, Rat
Details: Rabbit IgG Polyclonal
Applications: IHC, WB
Western Blot: TrkC [p Tyr820] Antibody [NBP1-03448]
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Reactivity: Mouse
Source: NS0
Accession #: Q6VNS1
Applications: Bioactivity
Recombinant Mouse TrkC Fc Chimera Protein Bioactivity
(2)
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His-tag

Reactivity: Mouse, Rat
Source: NS0
Accession #: Q6VNS1
Applications: Bioactivity
R&D Systems Recombinant Proteins and Enzymes
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Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC

Chemical Name: N-[3-[[2,3-Dihydro-2-oxo-3-(1H-pyrrol-2-ylmethylene)-1H-indol-6-yl]amino]-4-methylphenyl]-N'-[2-fluoro-5-(trifluoromethyl)phenyl]urea
Purity: ≥98%
Potent Trk inhibitor; inhibits TrkA, TrkB and TrkC
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TrkB and TrkC agonist; brain penetrant

Chemical Name: 2,2',2',2'''-[[(4-Chlorophenyl)methylene]bis(4,1-phenylenenitrilo)]tetrakisethanol
Purity: ≥97%
TrkB and TrkC agonist; brain penetrant
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Potent and selective pan-Trk inhibitor; peripherally restricted

Chemical Name: N-[5-[[2-Amino-7-(2-hydroxy-1,1-dimethylethyl)-7H-pyrrolo[2,3-d]pyrimidin-5-yl]carbonyl]-3-pyridinyl]-5-chloro-2-pyridineacetamide
Purity: ≥98%
Potent and selective pan-Trk inhibitor; peripherally restricted
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Reactivity: Human
R&D Systems VersaClone cDNA Plasmids
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Contains 4 membranes - each spotted in duplicate with 39 different RTK antibodies

Reactivity: Mouse
The Mouse Phospho-RTK Array detects multiple tyrosine phosphorylated receptors in untreated and ligand-treated cell lysates.
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Reactivity: Mouse
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Applications: AC
TrkC Antibody Blocking Peptide
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