AKT [Unconjugated]

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Background: Akt

Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.

Related Research Areas

• Apoptosis Intracellular Kinases
• Cancer Biomarkers
• Chemokine Receptor Intracellular Signaling
• Common gamma Chain Receptor Family
• Diabetic Peripheral Neuropathy
• GDNF Family
• IL-10 Family
• Interferons
• Intracellular Kinases
• Intracellular Kinases in the Akt Pathway
• Intracellular Signaling Molecules in Angiogenesis
• Kinases and Phosphatases in Endothelial Cells
• Multiple Myeloma
• Neurotrophin/Trk Family
• Notch Pathway
• PDGF Family
• Platelet Signaling
• Search Kinases and Phosphatases
• Signaling Molecules and Transcriptional Regulators of Tfh Cell Differentiation
• VEGF Family