Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 369505
View all BMP-2/BMP-7 Heterodimer Primary Antibodies »

Product Specifications

Immunogen

E. coli-derived recombinant human BMP‑2/BMP‑7 Heterodimer
Ala284-Arg396 (BMP-2), Ser293-His431 (BMP-7)
Accession # NP_001191, NP_001710

Specificity

Detects human BMP‑2/BMP‑7 Heterodimer in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 5% cross‑reactivity with recombinant human (rh) BMP-2 is observed, and no cross-reactivity with rhBMP-4/7, -4, -5, -6, -7, or -8 is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human BMP‑2/BMP‑7 Heterodimer Antibody

Application
Recommended Usage

Western Blot

1 µg/mL
Sample: Recombinant Human BMP-2/BMP-7 Heterodimer (Catalog # 3229-BM) under non-reducing conditions only

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background: BMP-2/BMP-7 Heterodimer

Bone Morphgenetic Protein 7 (BMP-7), also known as osteogenic protein 1 (OP-1), and BMP-2 are members of the BMP subgroup of the TGF-beta superfamily and signal through heterodimeric complexes composed of type I and type II BMP receptors. After proteolytic removal of their propeptides, BMP-2 and BMP-7 can associate into 38 kDa disulfide-linked heterodimers. The heterodimers are significantly more potent than either homodimer in osteoblast differentiation and bone formation assays. Human and mouse BMP-2 and BMP-7 share 100% and 98% aa sequence identity, respectively.

Long Name

Bone Morphogenetic Protein 2/7

Alternate Names

BDA2;BMP2A;Bone morphogenetic protein 2;SSFSC;SSFSC1

Entrez Gene IDs

650 (Human)

Gene Symbol

BMP2

UniProt

NP_001191, NP_001710

Additional BMP-2/BMP-7 Heterodimer Products

Product Documents for Human BMP‑2/BMP‑7 Heterodimer Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human BMP‑2/BMP‑7 Heterodimer Antibody

For research use only

Citations for Human BMP‑2/BMP‑7 Heterodimer Antibody

Customer Reviews for Human BMP‑2/BMP‑7 Heterodimer Antibody

There are currently no reviews for this product. Be the first to review Human BMP‑2/BMP‑7 Heterodimer Antibody and earn rewards!

Have you used Human BMP‑2/BMP‑7 Heterodimer Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies