When IL-2 R alpha is associated with the IL-2 receptor beta and gamma chains, a high affinity heterotrimeric receptor complex that transduces IL-2 signals is formed. The gamma chain is also the common signaling subunit of the high affinity receptor complex for IL-2, IL-4, IL-7, IL-9, IL-15 and IL-21.
Human Common gamma Chain (NP_000197) VersaClone cDNA
R&D Systems | Catalog # RDC1129
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Background: Common gamma Chain/IL-2 R gamma
Long Name
IL-2 Receptor gamma
Alternate Names
CD132, IL-2 R gamma, IL2R gamma, IL2RG
Gene Symbol
IL2RG
UniProt
Additional Common gamma Chain/IL-2 R gamma Products
Product Documents for Human Common gamma Chain (NP_000197) VersaClone cDNA
Certificate of Analysis
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Product Specific Notices for Human Common gamma Chain (NP_000197) VersaClone cDNA
For research use only
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Associated Pathways
IL-7 Signaling Pathways
IL-7 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types
IL-9 Signaling Pathways
IL-9 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types
IL-15 Signaling Pathways
IL-15 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types
IL-21 Signaling Pathways
IL-21 Signaling Pathways and their Primary Biological Effects in Different Immune Cell Types
Th2 Differentiation Pathway
Th17 Differentiation Pathway