Key Product Details

Species Reactivity

Human

Applications

Immunocytochemistry

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # 1039818
View all GPR88 Primary Antibodies »

Product Specifications

Immunogen

Human GPR88 synthetic peptide

Specificity

Detects human GPR88 in ELISA.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Scientific Data Images for Human GPR88 Antibody

Detection of GPR88 in NS0 Mouse Cell Line.

GPR88 was detected in immersion fixed NS0 mouse myeloma cell line transfected with GPR88 (positive staining) and absent in NS0 mouse myeloma cell line (wild type, negative control) using Mouse Anti-Human GPR88 Monoclonal Antibody (Catalog # MAB108281) at 3 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. Staining was performed our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Detection of GPR88 in HEK293 human cell line.

GPR88 was detected in immersion fixed HEK293 human cell line transfected with GPR88 (positive staining) and absent in HEK293 cell line (wild type, negative control) using Mouse Anti-Human GPR88 Monoclonal Antibody (Catalog # MAB108281) at 8 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Mouse IgG Secondary Antibody (red; Catalog # NL007) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

Applications for Human GPR88 Antibody

Application
Recommended Usage

Immunocytochemistry

3-25 µg/mL
Sample: Immersion fixed NS0 mouse myeloma cell line and HEK293 cell line transfected with GPR88

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

=
÷

Background: GPR88

GPR88 is an orphan receptor that probably belongs to the G-protein coupled receptor family.  Ligands for this receptor still largely remain unknown but agonists have been discovered.  It is a brain-specific receptor with almost exclusive expression in the striatum, being preferentially localized in medium spiny neurons.  Because of its expression, GPR88 is emerging as a drug target for CNS disorders such as schizophrenia, Parkinson's disease, anxiety, and addiction. Gpr88 KO mice data suggests that striatal GPR88 receptors influence activity in a range of procedures integrated by prefrontal, orbitofrontal and anterior cingulate cortico-striatal-thalamic loops leading to altered cognitive, motivational and reward evaluation processes.

Long Name

G Protein-coupled Receptor 88

Alternate Names

STRG

Entrez Gene IDs

54112 (Human); 64378 (Mouse); 64443 (Rat)

Gene Symbol

GPR88

Additional GPR88 Products

Product Documents for Human GPR88 Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human GPR88 Antibody

For research use only

Customer Reviews for Human GPR88 Antibody

There are currently no reviews for this product. Be the first to review Human GPR88 Antibody and earn rewards!

Have you used Human GPR88 Antibody?

Submit a review and receive an Amazon gift card!

$25/€18/£15/$25CAN/¥2500 Yen for a review with an image

$10/€7/£6/$10CAN/¥1110 Yen for a review without an image

Submit a review
Amazon Gift Card

FAQs

No product specific FAQs exist for this product.

View all FAQs for Antibodies