Human IGFBP-L1 Antibody

R&D Systems | Catalog # AF3877

R&D Systems

Key Product Details

Species Reactivity

Human

Applications

Western Blot

Label

Unconjugated

Antibody Source

Polyclonal Goat IgG
View all IGFBP-L1 Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human IGFBP-L1
Ser25-Met278
Accession # Q8WX77

Specificity

Detects human IGFBP-L1 in direct ELISAs and Western blots. In Western blots, approximately 15% cross-reactivity with recombinant mouse (rm) IGFBP-L1 is observed and less than 1% cross-reactivity with recombinant human IGFBP-1, -2, -3, -4, -5, -6, -7, and rmIGFBP-rP10 is observed.

Clonality

Polyclonal

Host

Goat

Isotype

IgG

Applications for Human IGFBP-L1 Antibody

Application
Recommended Usage

Western Blot

0.1 µg/mL
Sample: Recombinant Human IGFBP-L1

Formulation, Preparation, and Storage

Purification

Antigen Affinity-purified

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: IGFBP-L1

IGFBP-L1 is a secreted 38 kDa protein that shares 43% amino acid sequence identity with IGFBP-7 (IGFBP-rP1, Mac25). Although it was also referred to as IGFBP‑rP4 in one publication, it is distinct from Cyr61, a CCN family protein also named IGFBP-rP4 at one time. IGFBP-L1 contains an N-terminal IGFBP motif, a Kazal‑type serine protease inhibitor region and a C-terminal Ig-like domain. Human and mouse mature IGFBP-L1 share 76% amino acid sequence homology.

Long Name

Insulin-like Growth Factor Binding Protein-like 1

Alternate Names

IGFBP-RP4, IGFBPL1

Entrez Gene IDs

347252 (Human); 75426 (Mouse)

Gene Symbol

IGFBPL1

UniProt

Q8WX77

Additional IGFBP-L1 Products

Product Documents for Human IGFBP-L1 Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

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Product Specific Notices for Human IGFBP-L1 Antibody

For research use only

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