Human IL-13 R alpha 2 Antibody
Human IL-13 R alpha 2 Antibody Summary
Accession # Q14627
Human IL-13 R alpha 2 Sandwich Immunoassay
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: IL-13 R alpha 2
Two type I membrane proteins belonging to the hemopoietin receptor family have been cloned and shown to bind IL-13 with high affinity. The lower affinity IL-13 binding protein is now referred to as IL-13 R alpha 1 and is also known as CD213a. IL-13 R alpha 1 combines with IL-4 R alpha to form a high affinity receptor complex capable of transducing an IL-13-dependent proliferative signal. The higher affinity IL-13 binding protein, now referred to as IL-13 R alpha 2, does not induce a signal and acts as a decoy receptor (1, 2).
- Wood, N. et al. (2003) J. Exp. Med. 197:703.
- Kelly-Welch, A. et al. (2003) Science 300:1527.
Citations for Human IL-13 R alpha 2 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Interleukin (IL)-4, IL-13, and IL-17A differentially affect the profibrotic and proinflammatory functions of fibrocytes from asthmatic patients.
Authors: Bellini A, Marini MA, Bianchetti L, Barczyk M, Schmidt M, Mattoli S
Mucosal Immunol, 2011-12-21;5(2):140-9.
Sample Types: Whole Cells
Applications: Flow Cytometry
Interleukin-13 receptor alpha2 chain: a potential biomarker and molecular target for ovarian cancer therapy.
Authors: Kioi M, Kawakami M, Shimamura T, Husain SR, Puri RK
Sample Types: Serum, Whole Tissue
Applications: ELISA Development, IHC-P
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