Home / Myeloperoxidase/MPO / Human/Mouse Myeloperoxidase/MPO Antibody

Human/Mouse Myeloperoxidase/MPO Antibody

Catalog #: AF3667
67 Citations 4 Reviews Datasheet / COA / SDS
Catalog # Availability Size / Price Qty
AF3667
AF3667-SP
Detection of Human/Mouse Myeloperoxidase/MPO by Western Blot.
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Citations (67)
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Reviews (4)
Summary Data Examples Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human/Mouse Myeloperoxidase/MPO Antibody Summary

Species Reactivity
Human, Mouse
Specificity
Detects human and mouse Myeloperoxidase/MPO in Western blots. In direct ELISAs, less than 1% cross-reactivity with recombinant mouse EPPO is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
Mouse myeloma cell line NS0-derived recombinant mouse MPO
Met16-Thr718
Accession # P11247
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.
Label
Unconjugated

Applications

Recommended Concentration
Sample
Western Blot
0.5 µg/mL
See below
Simple Western
5 µg/mL
See below
Immunohistochemistry
1-15 µg/mL
See below
Immunocytochemistry
5-15 µg/mL
See below

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Scientific Data

Western Blot Detection of Human/Mouse Myeloperoxidase/MPO antibody by Western Blot. View Larger

Detection of Human/Mouse Myeloperoxidase/MPO by Western Blot. Western blot shows lysates of HL-60 human acute promyelocytic leukemia cell line, human neutrophil cells, and mouse spleen tissue. PVDF membrane was probed with 0.5 µg/mL of Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) followed by HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF019). A specific band was detected for Myeloperoxidase/MPO at approximately 60 kDa (as indicated). This experiment was conducted under reducing conditions and using Immunoblot Buffer Group 2.

Immunocytochemistry Myeloperoxidase/MPO antibody in Mouse Splenocytes by Immunocytochemistry (ICC). View Larger

Myeloperoxidase/MPO in Mouse Splenocytes. Myeloperoxidase/MPO was detected in immersion fixed mouse splenocytes using Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) at 15 µg/mL for 3 hours at room temperature. Cells were stained using the NorthernLights™ 557-conjugated Anti-Goat IgG Secondary Antibody (red; NL001) and counterstained with DAPI (blue). Specific staining was localized to cytoplasm. View our protocol for Fluorescent ICC Staining of Non-adherent Cells.

For human Immunocytochemistry samples, we recommend Mouse Anti-Human Myeloperoxidase/ MPO Monoclonal Antibody (MAB3174).

Immunohistochemistry Myeloperoxidase/MPO antibody in Mouse Spleen Tissue by Immunohistochemistry (IHC-P). View Larger

Myeloperoxidase/MPO in Mouse Spleen Tissue. Myeloperoxidase/MPO was detected in immersion fixed paraffin-embedded sections of mouse spleen tissue using Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) at 1 µg/mL for 1 hour at room temperature followed by incubation with the Anti-Goat IgG VisUCyte™ HRP Polymer Antibody (VC004). Tissue was stained using DAB (brown) and counterstained with hematoxylin (blue). Specific staining was localized to lymphocytes. Staining was performed using our IHC Staining with VisUCyte HRP Polymer Detection Reagents.

For human Immunohistochemistry samples, we recommend Mouse Anti-Human Myeloperoxidase/ MPO Monoclonal Antibody (MAB3174).

Simple Western Detection of Mouse Myeloperoxidase/MPO antibody by Simple Western<SUP>TM</SUP>. View Larger

Detection of Mouse Myeloperoxidase/MPO by Simple WesternTM. Simple Western lane view shows lysates of mouse spleen tissue, loaded at 0.2 mg/mL. A specific band was detected for Myeloperoxidase/MPO at approximately 67 kDa (as indicated) using 5 µg/mL of Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) followed by 1:50 dilution of HRP-conjugated Anti-Goat IgG Secondary Antibody (HAF109). This experiment was conducted under reducing conditions and using the 12-230 kDa separation system.

Immunohistochemistry Myeloperoxidase/MPO antibody in Human Spleen by Immunohistochemistry (IHC-P). View Larger

Myeloperoxidase/MPO in Human Spleen. Myeloperoxidase/MPO was detected in immersion fixed paraffin-embedded sections of human spleen using 3 µg/mL Goat Anti-Human/Mouse Myeloperoxidase/MPO Antigen Affinity-purified Polyclonal Antibody (Catalog # AF3667) overnight at 4 °C. Before incubation with the primary antibody tissue was subjected to heat-induced epitope retrieval using Antigen Retrieval Reagent-Basic (Catalog # CTS013). Tissue was stained with the Anti-Goat HRP-DAB Cell & Tissue Staining Kit (brown; Catalog # CTS008) and counterstained with hematoxylin (blue). View our protocol for Chromogenic IHC Staining of Paraffin-embedded Tissue Sections.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Myeloperoxidase/MPO

Myeloperoxidase (MPO) is a hemeprotein that belongs to the XPO subfamily of the heme peroxidase superfamily. MPO is synthesized as a preproprotein that undergoes proteolytic processing to generate a disulfide-linked heterodimer of the N-terminal beta -subunit (12 kDa) and C-terminal alpha subunit (60 kDa). Active MPO is a tetramer of two beta -subunits and two alpha -subunits that are also disulfide-linked through the two alpha -subunits. MPO is stored in granules and is an abundant protein in neutrophils and monocytes. MPO is released upon activation to catalyze the formation of powerful oxidants such as hypochlorous acid, which kills microbes. Unprocessed pro-MPO can also be released. Mouse MPO shares 87% amino acid sequence identity with that of human MPO.

Entrez Gene IDs
4353 (Human); 17523 (Mouse); 303413 (Rat)
Alternate Names
EC 1.11.1; EC 1.11.1.7; MPO; Myeloperoxidase

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Citations for Human/Mouse Myeloperoxidase/MPO Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

67 Citations: Showing 1 - 10
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  1. IL-1beta neutralization prevents diastolic dysfunction development, but lacks hepatoprotective effect in an aged mouse model of NASH
    Authors: D Kucsera, VE Tóth, NV Sayour, T Kovács, TG Gergely, M Ruppert, T Radovits, A Fábián, A Kovács, B Merkely, P Ferdinandy, ZV Varga
    Scientific Reports, 2023;13(1):356.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  2. High PANX1 Expression Leads to Neutrophil Recruitment and the Formation of a High Adenosine Immunosuppressive Tumor Microenvironment in Basal-like Breast Cancer
    Authors: W Chen, B Li, F Jia, J Li, H Huang, C Ni, W Xia
    Cancers, 2022;14(14):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  3. Disulfiram inhibits neutrophil extracellular trap formation protecting rodents from acute lung injury and SARS-CoV-2 infection
    Authors: JM Adrover, L Carrau, J Da beta ler-Ple, Y Bram, V Chandar, S Houghton, D Redmond, JR Merrill, M Shevik, BR tenOever, SK Lyons, RE Schwartz, M Egeblad
    JCI Insight, 2022;0(0):.
    Species: Hamster
    Sample Types: Whole Tissue
    Applications: IHC
  4. ADAM8 signaling drives neutrophil migration and ARDS severity
    Authors: C Conrad, D Yildiz, SJ Cleary, A Margraf, L Cook, U Schlomann, B Panaretou, JL Bowser, H Karmouty-Q, J Li, NK Berg, SC Martin, A Aljohmani, SF Moussavi-H, KM Wang, JJ Tian, M Magnen, C Valet, L Qiu, JP Singer, HK Eltzschig, CAPSys Stu, W Bertrams, S Herold, N Suttorp, B Schmeck, ZT Ball, A Zarbock, MR Looney, JW Bartsch
    JCI Insight, 2022;7(3):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  5. Epigallocatechin-3-gallate reduces neutrophil extracellular trap formation and tissue injury in severe acute pancreatitis
    Authors: H Li, C Qiao, L Zhao, Q Jing, D Xue, Y Zhang
    Journal of leukocyte biology, 2022;0(0):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  6. Depletion of gammadelta T Cells Leads to Reduced Angiogenesis and Increased Infiltration of Inflammatory M1-like Macrophages in Ischemic Muscle Tissue
    Authors: C Arnholdt, K Kumaraswam, P Götz, M Kübler, M Lasch, E Deindl
    Cells, 2022;11(9):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  7. Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice
    Authors: D Ye, J Yao, W Du, C Chen, Y Yang, K Yan, J Li, Y Xu, S Zang, Y Zhang, X Rong, R Zhang, A Xu, J Guo
    Cellular and Molecular Gastroenterology and Hepatology, 2022;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  8. Deficiency of leukocyte-specific protein 1 (LSP1) alleviates asthmatic inflammation in a mouse model
    Authors: NPK Le, AF do Nascime, D Schneberge, CC Quach, X Zhang, GK Aulakh, W Dawicki, L Liu, JR Gordon, B Singh
    Respiratory Research, 2022;23(1):165.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  9. Blocking the human common beta subunit of the GM-CSF, IL-5 and IL-3 receptors markedly reduces hyperinflammation in ARDS models
    Authors: H Wang, DJ Tumes, TR Hercus, KH Yip, C Aloe, R Vlahos, AF Lopez, N Wilson, CM Owczarek, S Bozinovski
    Cell Death & Disease, 2022;13(2):137.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  10. Dysfunctional ERG signaling drives pulmonary vascular aging and persistent fibrosis
    Authors: N Caporarell, J Lee, TX Pham, DL Jones, J Guan, PA Link, JA Meridew, G Marden, T Yamashita, CA Osborne, AV Bhagwate, SK Huang, RF Nicosia, DJ Tschumperl, M Trojanowsk, G Ligresti
    Nature Communications, 2022;13(1):4170.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  11. Inhibition of neutrophil elastase prevents cigarette smoke exposure-induced formation of neutrophil extracellular traps and improves lung function in a mouse model of chronic obstructive pulmonary disease
    Authors: K Wang, Y Liao, X Li, R Wang, Z Zeng, M Cheng, L Gao, D Xu, F Wen, T Wang, J Chen
    International immunopharmacology, 2022;114(0):109537.
    Species: Human
    Sample Types: Whole Cell
    Applications: ICC
  12. Neutrophil Extracellular Traps Promote NLRP3 Inflammasome Activation and Glomerular Endothelial Dysfunction in Diabetic Kidney Disease
    Authors: A Gupta, K Singh, S Fatima, S Ambreen, S Zimmermann, R Younis, S Krishnan, R Rana, I Gadi, C Schwab, R Biemann, K Shahzad, V Rani, S Ali, PR Mertens, S Kohli, B Isermann
    Nutrients, 2022;14(14):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  13. CLEC5A is critical in Pseudomonas aeruginosa-induced acute lung injury
    Authors: PS Sung, YC Peng, SP Yang, CH Chiu, SL Hsieh
    JCI Insight, 2022;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  14. Scavenging dicarbonyls with 5'-O-pentyl-pyridoxamine increases HDL net cholesterol efflux capacity and attenuates atherosclerosis and insulin resistance
    Authors: J Huang, H Tao, PG Yancey, Z Leuthner, LS May-Zhang, JY Jung, Y Zhang, L Ding, V Amarnath, D Liu, S Collins, SS Davies, MF Linton
    Molecular Metabolism, 2022;67(0):101651.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  15. A novel phosphocholine-mimetic inhibits a pro-inflammatory conformational change in C-reactive protein
    Authors: J Zeller, KS Cheung Tun, TL Nero, JD McFadyen, G Krippner, B Bogner, S Kreuzaler, J Kiefer, VK Horner, D Braig, H Danish, S Baratchi, M Fricke, X Wang, MG Kather, B Kammerer, KJ Woollard, P Sharma, CJ Morton, G Pietersz, MW Parker, K Peter, SU Eisenhardt
    Embo Molecular Medicine, 2022;0(0):e16236.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  16. KDM6A Loss Recruits Tumor-Associated Neutrophils and Promotes Neutrophil Extracellular Trap Formation in Pancreatic Cancer
    Authors: J Yang, L Jin, HS Kim, F Tian, Z Yi, K Bedi, M Ljungman, M Pasca di M, H Crawford, J Shi
    Cancer Research, 2022;0(0):OF1-OF14.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  17. Eosinophil extracellular traps drive asthma progression through neuro-immune signals
    Authors: Y Lu, Y Huang, J Li, J Huang, L Zhang, J Feng, J Li, Q Xia, Q Zhao, L Huang, S Jiang, S Su
    Nature Cell Biology, 2021;23(10):1060-1072.
    Species: Mouse
    Sample Types: BALF
    Applications: ICC
  18. AMPK hyperactivation promotes dendrite retraction, synaptic loss, and neuronal dysfunction in glaucoma
    Authors: N Belforte, J Agostinone, L Alarcon-Ma, D Villafranc, F Dotigny, JL Cueva Varg, A Di Polo
    Molecular Neurodegeneration, 2021;16(1):43.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  19. ELMO1 signaling is a promoter of osteoclast function and bone loss
    Authors: S Arandjelov, JSA Perry, M Zhou, A Ceroi, I Smirnov, SF Walk, LS Shankman, I Cambré, S Onengut-Gu, D Elewaut, TP Conrads, KS Ravichandr
    Nature Communications, 2021;12(1):4974.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  20. NETosis in the pathogenesis of acute lung injury following cutaneous chemical burns
    Authors: R Surolia, FJ Li, Z Wang, M Kashyap, RK Srivastava, AM Traylor, P Singh, KG Dsouza, H Kim, JF Pittet, JW Zmijewski, A Agarwal, M Athar, A Ahmad, VB Antony
    JCI Insight, 2021;6(10):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  21. Sprague Dawley Rats Gaining Weight on a High Energy Diet Exhibit Damage to Taste Tissue Even after Return to a Healthy Diet
    Authors: F Harnischfe, F O'Connell, M Weiss, B Axelrod, A Hajnal, K Czaja, PM Di Lorenzo, R Dando
    Nutrients, 2021;13(9):.
    Species: Rat
    Sample Types: Whole Tissue
    Applications: IHC
  22. Immunomodulatory role of reactive oxygen species and nitrogen species during T cell-driven neutrophil-enriched acute and chronic cutaneous delayed-type hypersensitivity reactions
    Authors: R Mehling, J Schwenck, C Lemberg, C Trautwein, L Zizmare, D Kramer, A Müller, B Fehrenbach, I Gonzalez-M, L Quintanill, K Schröder, RP Brandes, M Schaller, W Ruf, M Eichner, K Ghoreschi, M Röcken, BJ Pichler, M Kneilling
    Theranostics, 2021;11(2):470-490.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  23. Absence of Cold-Inducible RNA-Binding Protein (CIRP) Promotes Angiogenesis and Regeneration of Ischemic Tissue by Inducing M2-Like Macrophage Polarization
    Authors: M Kübler, S Beck, S Fischer, P Götz, K Kumaraswam, H Ishikawa-A, M Lasch, E Deindl
    Biomedicines, 2021;9(4):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  24. CXCR4 and CXCR7 Inhibition Ameliorates the Formation of Platelet-Neutrophil Complexes and Neutrophil Extracellular Traps through Adora2b Signaling
    Authors: KC Ngamsri, RA Putri, C Jans, K Schindler, A Fuhr, Y Zhang, J Gamper-Tsi, S Ehnert, FM Konrad
    International Journal of Molecular Sciences, 2021;22(24):.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  25. Modulation of Cellular NAD+ Attenuates Cancer-Associated Hypercoagulability and Thrombosis via the Inhibition of Tissue Factor and Formation of Neutrophil Extracellular Traps
    Authors: W Cao, MY Zhu, SH Lee, SB Lee, HJ Kim, BO Park, CH Yoon, D Khadka, GS Oh, H Shim, TH Kwak, HS So
    International Journal of Molecular Sciences, 2021;22(21):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  26. Evidence of a Myenteric Plexus Barrier and Its Macrophage-Dependent Degradation During Murine Colitis: Implications in Enteric Neuroinflammation
    Authors: D Dora, S Ferenczi, R Stavely, VE Toth, ZV Varga, T Kovacs, I Bodi, R Hotta, KJ Kovacs, AM Goldstein, N Nagy
    Cellular and Molecular Gastroenterology and Hepatology, 2021;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  27. Hsp90-stabilized MIF supports tumor progression via macrophage recruitment and angiogenesis in colorectal cancer
    Authors: L Klemke, T De Oliveir, D Witt, N Winkler, H Bohnenberg, R Bucala, LC Conradi, R Schulz-Hed
    Cell Death & Disease, 2021;12(2):155.
    Species: Mouse
    Sample Types: Organoid
    Applications: IHC
  28. Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis
    Authors: EY Lin, HJ Lai, YK Cheng, KQ Leong, LC Cheng, YC Chou, YC Peng, YH Hsu, HS Chiang
    Biomedicines, 2020;8(8):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: ELISA Capture
  29. Type I IFN exacerbates disease in tuberculosis-susceptible mice by inducing neutrophil-mediated lung inflammation and NETosis
    Authors: L Moreira-Te, PJ Stimpson, E Stavropoul, S Hadebe, P Chakravart, M Ioannou, IV Aramburu, E Herbert, SL Priestnall, A Suarez-Bon, J Sousa, KL Fonseca, Q Wang, S Vashakidze, P Rodríguez-, C Vilaplana, M Saraiva, V Papayannop, A O'Garra
    Nat Commun, 2020;11(1):5566.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  30. Suppression of Metastatic Melanoma Growth in Lung by Modulated Electro-Hyperthermia Monitored by a Minimally Invasive Heat Stress Testing Approach in Mice
    Authors: MJ Thomas, E Major, A Benedek, I Horváth, D Máthé, R Bergmann, AM Szász, T Krenács, Z Benyó
    Cancers, 2020;12(12):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  31. Neutrophil extracellular traps exacerbate neurological deficits after traumatic brain injury
    Authors: K Vaibhav, M Braun, K Alverson, H Khodadadi, A Kutiyanawa, A Ward, C Banerjee, T Sparks, A Malik, MH Rashid, MB Khan, MF Waters, DC Hess, AS Arbab, JR Vender, N Hoda, B Baban, KM Dhandapani
    Sci Adv, 2020;6(22):eaax8847.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  32. The Metalloproteinase ADAMTS5 Is Expressed by Interstitial Inflammatory Cells in IgA Nephropathy and Is Proteolytically Active on the Kidney Matrix
    Authors: S Taylor, M Whitfield, J Barratt, A Didangelos
    J. Immunol., 2020;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  33. Alveolar barrier disruption in varicella pneumonia is associated with neutrophil extracellular trap formation
    Authors: WJ Ouwendijk, HJ van den Ha, MW Delany, JJ van Kampen, GP van Nierop, T Mehraban, F Zaaraoui-B, WF van IJcken, JM van den Br, RD De Vries, AC Andeweg, GM Verjans
    JCI Insight, 2020;0(0):.
    Species: Primate
    Sample Types: Whole Tissue
    Applications: IHC
  34. Immunohistological Analysis of Neutrophils and Neutrophil Extracellular Traps in Human Thrombemboli Causing Acute Ischemic Stroke
    Authors: F Essig, AM Kollikowsk, M Pham, L Solymosi, G Stoll, KG Haeusler, P Kraft, MK Schuhmann
    Int J Mol Sci, 2020;21(19):.
    Species: Human
    Sample Types: Whole Tissue
    Applications: IHC
  35. Neutrophil Extracellular Traps Impair Intestinal Barrier Function during Experimental Colitis
    Authors: EY Lin, HJ Lai, YK Cheng, KQ Leong, LC Cheng, YC Chou, YC Peng, YH Hsu, HS Chiang
    Biomedicines, 2020;8(8):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: ELISA Capture
  36. Therapeutic ACPA inhibits NET formation: a potential therapy for neutrophil-mediated inflammatory diseases
    Authors: RGS Chirivi, JWG van Rosmal, M van der Li, M Euler, G Schmets, G Bogatkevic, K Kambas, J Hahn, Q Braster, O Soehnlein, MH Hoffmann, HHGV Es, JMH Raats
    Cell. Mol. Immunol., 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  37. Deficiency in the glycosyltransferase Gcnt1 increases susceptibility to tuberculosis through a mechanism involving neutrophils
    Authors: KL Fonseca, AR Maceiras, R Matos, L Simoes-Cos, J Sousa, B Cá, L Barros, AI Fernandes, S Mereiter, R Reis, J Gomes, G Tapia, P Rodríguez-, M Martín-Cés, S Vashakidze, S Gogishvili, K Nikolaishv, R Appelberg, F Gärtner, PNS Rodrigues, C Vilaplana, CA Reis, A Magalhães, M Saraiva
    Mucosal Immunol, 2020;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  38. Programmed 'disarming' of the neutrophil proteome reduces the magnitude of inflammation
    Authors: JM Adrover, A Aroca-Crev, G Crainiciuc, F Ostos, Y Rojas-Vega, A Rubio-Ponc, C Cilloniz, E Bonzón-Kul, E Calvo, D Rico, MA Moro, C Weber, I Lizasoaín, A Torres, J Ruiz-Cabel, J Vázquez, A Hidalgo
    Nat. Immunol., 2020;21(2):135-144.
    Species: Human
    Sample Types: Whole Cells
    Applications: Functional Assay
  39. Histones, DNA, and Citrullination Promote Neutrophil Extracellular Trap Inflammation by Regulating the Localization and Activation of TLR4
    Authors: TD Tsouroukts, A Warnatsch, M Ioannou, D Hoving, Q Wang, V Papayannop
    Cell Rep, 2020;31(5):107602.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  40. Extracellular vesicles from CLEC2-activated platelets enhance dengue virus-induced lethality via CLEC5A/TLR2
    Authors: PS Sung, TF Huang, SL Hsieh
    Nat Commun, 2019;10(1):2402.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC
  41. Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells
    Authors: N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald
    JCI Insight, 2019;0(0):.
    Species: Xenograft
    Sample Types: Whole Tissue
    Applications: IHC-P
  42. Lugdunin amplifies innate immune responses in the skin in synergy with host- and microbiota-derived factors
    Authors: K Bitschar, B Sauer, J Focken, H Dehmer, S Moos, M Konnerth, NA Schilling, S Grond, H Kalbacher, FC Kurschus, F Götz, B Krismer, A Peschel, B Schittek
    Nat Commun, 2019;10(1):2730.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  43. Qingnao dripping pills mediate immune-inflammatory response and MAPK signaling pathway after acute ischemic stroke in rats
    Authors: Z Zeng, Y Zhang, X Liang, F Wang, J Zhao, Z Xu, X Liu, X Liu
    J. Pharmacol. Sci., 2019;0(0):.
    Species: Rat
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  44. Acute Liver Injury after CCl4 Administration is Independent of Smad7 Expression in Myeloid Cells
    Authors: J Endig, L Unrau, P Sprezyna, S Rading, M Karsak, D Goltz, LC Heukamp, G Tiegs, L Diehl
    Int J Mol Sci, 2019;20(22):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  45. Keratinocyte-derived I&kappaB? drives psoriasis and associated systemic inflammation
    Authors: S Lorscheid, A Müller, J Löffler, C Resch, P Bucher, FC Kurschus, A Waisman, K Schäkel, S Hailfinger, K Schulze-Os, D Kramer
    JCI Insight, 2019;4(22):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  46. Locally instructed CXCR4hi neutrophils trigger environment-driven allergic asthma through the release of neutrophil extracellular traps
    Authors: C Radermecke, C Sabatel, C Vanwinge, C Ruscitti, P Maréchal, F Perin, J Schyns, N Rocks, M Toussaint, D Cataldo, SL Johnston, F Bureau, T Marichal
    Nat. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  47. Neutrophils escort circulating tumour cells to enable cell cycle progression
    Authors: BM Szczerba, F Castro-Gin, M Vetter, I Krol, S Gkountela, J Landin, MC Scheidmann, C Donato, R Scherrer, J Singer, C Beisel, C Kurzeder, V Heinzelman, C Rochlitz, WP Weber, N Beerenwink, N Aceto
    Nature, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: ICC
  48. Mesenchymal stem cells attenuate blood-brain barrier leakage after cerebral ischemia in mice
    Authors: Z Cheng, L Wang, M Qu, H Liang, W Li, Y Li, L Deng, Z Zhang, GY Yang
    J Neuroinflammation, 2018;15(1):135.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  49. GWAS for Interleukin-1? levels in gingival crevicular fluid identifies IL37 variants in periodontal inflammation
    Authors: S Offenbache, Y Jiao, SJ Kim, J Marchesan, KL Moss, L Jing, K Divaris, S Bencharit, CS Agler, T Morelli, S Zhang, L Sun, WT Seaman, D Cowley, SP Barros, JD Beck, M Munz, AS Schaefer, KE North
    Nat Commun, 2018;9(1):3686.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  50. Matrix metalloproteinase-9 deficiency protects mice from severe influenza A viral infection
    Authors: J Rojas-Quin, X Wang, J Tipper, PR Burkett, J Zuñiga, AR Ashtekar, F Polverino, A Rout, I Yambayev, C Hernández, L Jimenez, G Ramírez, KS Harrod, CA Owen
    JCI Insight, 2018;3(24):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  51. Reg3? is associated with cardiac inflammation and provides prognostic information in patients with acute coronary syndrome
    Authors: H Lörchner, C Widera, Y Hou, A Elsässer, H Warnecke, E Giannitsis, JS Hulot, T Braun, KC Wollert, J Pöling
    Int. J. Cardiol., 2018;258(0):7-13.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  52. Host DNA released by NETosis promotes rhinovirus-induced type-2 allergic asthma exacerbation
    Authors: M Toussaint, DJ Jackson, D Swieboda, A Guedán, TD Tsouroukts, YM Ching, C Radermecke, H Makrinioti, J Aniscenko, MR Edwards, R Solari, F Farnir, V Papayannop, F Bureau, T Marichal, SL Johnston
    Nat. Med., 2017;23(6):681-691.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  53. Obesity promotes prolonged ovalbumin-induced airway inflammation modulating Th1, Th2 and Th17 immune responses in BALB/c mice
    Authors: FM Silva, EE Oliveira, AC Gouveia, AS Brugiolo, CC Alves, JO Correa, J Gameiro, J Mattes, HC Teixeira, AP Ferreira
    Clin. Exp. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  54. Topical Fibronectin Improves Wound Healing of Irradiated Skin
    Authors: MB Johnson, B Pang, DJ Gardner, S Niknam-Ben, V Soundaraja, A Bramos, DP Perrault, K Banks, GK Lee, RY Baker, GH Kim, S Lee, Y Chai, M Chen, W Li, L Kwong, YK Hong, AK Wong
    Sci Rep, 2017;7(1):3876.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  55. Cell-penetrating interactomic inhibition of nuclear factor-kappa B in a mouse model of postoperative cognitive dysfunction
    Authors: SY Cheon, JM Kim, EH Kam, CC Ho, EJ Kim, S Chung, JH Jeong, DD Lee, SW Lee, BN Koo
    Sci Rep, 2017;7(1):13482.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  56. The blood-borne sialyltransferase ST6Gal-1 is a negative systemic regulator of granulopoiesis
    Authors: CWL Dougher, A Buffone, MJ Nemeth, M Nasirikena, EE Irons, PN Bogner, JTY Lau
    J. Leukoc. Biol., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Lysates
    Applications: Western Blot
  57. Neutrophil Attack Triggers Extracellular Trap-Dependent Candida Cell Wall Remodeling and Altered Immune Recognition
    PLoS Pathog, 2016;12(5):e1005644.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  58. Swimming Motility Mediates the Formation of Neutrophil Extracellular Traps Induced by Flagellated Pseudomonas aeruginosa
    PLoS Pathog., 2016;12(11):e1005987.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: IHC
  59. Beneficial Effects of Sodium Phenylbutyrate Administration During Infection with Salmonella enterica serovar Typhimurium
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  60. PAD4 Deficiency Decreases Inflammation and Susceptibility to Pregnancy Loss in a Mouse Model
    Authors: Luise Erpenbeck
    Biol. Reprod, 2016;95(6):132.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P
  61. Correction: A chitin-like component on sclerotic cells of fonsecaea pedrosoi inhibits dectin-1-mediated murine Th17 development by masking beta-glucans.
    PLoS ONE, 2015;10(3):e0119244.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  62. Rhadinovirus host entry by co-operative infection.
    Authors: Lawler C, Milho R, May J, Stevenson P
    PLoS Pathog, 2015;11(3):e1004761.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  63. IL-33 targeting attenuates intestinal mucositis and enhances effective tumor chemotherapy in mice.
    Authors: Guabiraba R, Besnard A, Menezes G, Secher T, Jabir M, Amaral S, Braun H, Lima-Junior R, Ribeiro R, Cunha F, Teixeira M, Beyaert R, Graham G, Liew F
    Mucosal Immunol, 2014;7(5):1079-93.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  64. Lactobacillus rhamnosus GG and Bifidobacterium longum attenuate lung injury and inflammatory response in experimental sepsis.
    Authors: Khailova L, Petrie B, Baird C, Dominguez Rieg J, Wischmeyer P
    PLoS ONE, 2014;9(5):e97861.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC
  65. The cytokine IL-22 promotes pathogen colonization by suppressing related commensal bacteria.
    Authors: Behnsen J, Jellbauer S, Wong C, Edwards R, George M, Ouyang W, Raffatellu M
    Immunity, 2014;40(2):262-73.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: Western Blot
  66. Transcriptomic analysis of host immune and cell death responses associated with the influenza A virus PB1-F2 protein.
    Authors: Le Goffic R, Leymarie O, Chevalier C, Rebours E, Da Costa B, Vidic J, Descamps D, Sallenave JM, Rauch M, Samson M, Delmas B
    PLoS Pathog., 2011;7(8):e1002202.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-Fr
  67. Tissue inhibitor of metalloproteinases 3 regulates resolution of inflammation following acute lung injury.
    Authors: Gill SE, Huizar I, Bench EM
    Am. J. Pathol., 2010;176(1):64-73.
    Species: Mouse
    Sample Types: Tissue Homogenates
    Applications: ELISA Development

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Isotype Controls

Normal Goat IgG Control

AB-108-C
351 Citations
18 Reviews
1 Image
Ctrl

Reconstitution Buffers

Reconstitution Buffer 1 (PBS)

RB01
3 Reviews

Secondary Antibodies

Chicken Anti-Goat IgG Biotinylated Antibody

BAF019
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Donkey Anti-Goat IgG (H+L) PerCP-conjugated Antibody

F0124
Flow

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Goat IgG (H+L) APC-conjugated Antibody

F0108
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1 Image
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Goat IgG (H+L) Fluorescein-conjugated Antibody

F0109
3 Citations
1 Image
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Goat IgG (H+L) PE-conjugated Antibody

F0107
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1 Image
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Goat IgG HRP-conjugated Antibody

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WB,Simple Western

Goat IgG HRP-conjugated Antibody

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Goat IgG Horseradish Peroxidase-conjugated Antibody

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17 Citations
1 Image
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Goat IgG VisUCyte HRP Polymer

VC004
5 Citations
1 Image
IHC

Rabbit Anti-Goat IgG (H+L) Antibody, X Absorbed

R-401-C-ABS
WB,ELISA

Rabbit Anti-Goat IgG Biotinylated Antibody

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Human/Mouse Myeloperoxidase/MPO Antibody
By Anonymous on 01/24/2023
Application: ICC/IF Sample Tested: Spleen tissue Species: Mouse
Immunocytochemistry/Immunofluorescence Human/Mouse Myeloperoxidase/MPO Antibody AF3667
Human/Mouse Myeloperoxidase/MPO Antibody
By Anonymous on 06/27/2021
Application: IHC Sample Tested: Epithelium Species: Mouse
Immunohistochemistry Human/Mouse Myeloperoxidase/MPO Antibody AF3667
Human/Mouse Myeloperoxidase/MPO Antibody
By Anonymous on 07/27/2019
Application: ICC/IF Sample Tested: Peritoneal macrophages Species: Mouse

DAPI-blue
MPO-green

Immunocytochemistry/Immunofluorescence Human/Mouse Myeloperoxidase/MPO Antibody AF3667
Human/Mouse Myeloperoxidase/MPO Antibody
By Anonymous on 09/30/2018
Application: ICC/IF Sample Tested: Bone marrow cells Species: Mouse
Immunocytochemistry/Immunofluorescence Human/Mouse Myeloperoxidase/MPO Antibody AF3667