Human NgR2/NgRH1 Antibody
Human NgR2/NgRH1 Antibody Summary
Accession # Q86UN3
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
NgR2, also known as reticulon 4 receptor-like 2 and NgR2, is a 60 kDa glycosylphosphatidylinositol-anchored protein that is expressed primarily in the brain. It contains eight leucine-rich repeats that are flanked by cysteine-rich sequences at both the N- as well as the C-terminus. Membrane-anchored NgR2 can be solubilized through the action of phospholipase or an unidentified MT-MMP to generate a 46 kDa soluble receptor. Mature human NgR2 shares 48% aa sequence identity with human NgRH2. It also shares 96% aa sequence identity with mouse and rat mature NgR2.
Citations for Human NgR2/NgRH1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 3
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The NOGO receptor NgR2, a novel alphaVbeta3 integrin effector, induces neuroendocrine differentiation in prostate cancer
Authors: F Quaglia, SR Krishn, K Sossey-Ala, PS Rana, E Pluskota, PH Park, CD Shields, S Lin, P McCue, AV Kossenkov, Y Wang, DW Goodrich, SY Ku, H Beltran, WK Kelly, E Corey, M Klose, C Bandtlow, Q Liu, DC Altieri, EF Plow, LR Languino
Scientific Reports, 2022-11-07;12(1):18879.
Sample Types: Protein
Applications: Western Blot
Ganglioside inhibition of neurite outgrowth requires Nogo receptor function: identification of interaction sites and development of novel antagonists.
Authors: Williams G, Wood A, Williams EJ, Gao Y, Mercado ML, Katz A, Joseph-McCarthy D, Bates B, Ling HP, Aulabaugh A, Zaccardi J, Xie Y, Pangalos MN, Walsh FS, Doherty P
J. Biol. Chem., 2008-04-14;283(24):16641-52.
Sample Types: Tissue Homogenates
Applications: Western Blot
A role for Nogo receptor in macrophage clearance from injured peripheral nerve.
Authors: Fry EJ, Ho C, David S
Sample Types: Cell Lysates, Whole Cells
Applications: Flow Cytometry, Slot Blot
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