Human PEG10 Antibody Summary
Accession # Q86TG7
This antibody functions as an ELISA capture antibody when paired with Mouse Anti-Human PEG10 Monoclonal Antibody (Catalog # MAB9975).
This product is intended for assay development on various assay platforms requiring antibody pairs.
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of PEG-10 in Human HepG2 cell line by Flow Cytometry. HepG2 human hepatoma cell line was stained with Mouse Anti-Human PEG-10 Monoclonal Antibody (Catalog # MAB99751, filled histogram) or isotype control antibody (Catalog # MAB003, open histogram), followed by PE-conjugated Anti-Mouse IgG Secondary Antibody(Catalog # F0102B). To facilitate intracellular staining, cells were fixed and permeabilized with FlowX FoxP3 Fixation & Permeabilization Buffer Kit (Catalog # FC012). View our protocol for Staining Intracellular Molecules.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Paternally Expressed Gene-10, or PEG10 (a.k.a Retrotransposon-derived protein PEG10, EDR, MART2, MEF3L1 and RGAG3) is a 708 amino acids (aa) protein encoded by the PEG10 gene. PEG-10 Inhibits the TGF-beta signaling by interacting with the TGF-beta receptor ALK1, possibly playing a key role in epithelial-mesenchymal transition (EMT). PEG-10 has been suggested to participate in cell proliferation, differentiation and cell apoptosis processes and identified as a prognostic biomarker for progression of several carcinomas, like breast, lung, liver and pancreatic carcinomas.
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