Key Product Details

Species Reactivity

Human

Applications

Western Blot, Immunoprecipitation

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG2B Clone # 474034
View all PGLYRP4/PGRP-I beta Primary Antibodies »

Product Specifications

Immunogen

Mouse myeloma cell line NS0-derived recombinant human PGLYRP4/PGRP-I beta
Asp18-His373
Accession # Q96LB8

Specificity

Detects human PGLYRP4/PGRP-I beta in direct ELISAs and Western blots. In direct ELISAs and Western blots, no cross-reactivity with recombinant mouse PGRP-I beta or recombinant human PGRP-S is observed.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG2B

Applications for Human PGLYRP4/PGRP‑I beta Antibody

Application
Recommended Usage

Immunoprecipitation

25 µg/mL
Sample: Conditioned cell culture medium spiked with Recombinant Human PGLYRP4/PGRP-I beta, see our available Western blot detection antibodies

Western Blot

1 µg/mL
Sample: Recombinant Human PGLYRP4/PGRP-I beta

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Reconstitution

Reconstitute at 0.5 mg/mL in sterile PBS. For liquid material, refer to CoA for concentration.

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Shipping

Lyophilized product is shipped at ambient temperature. Liquid small pack size (-SP) is shipped with polar packs. Upon receipt, store immediately at the temperature recommended below.

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Calculators

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: PGLYRP4/PGRP-I beta

Peptidoglycan recognition protein intermediate beta (PGRP-I beta ), also known as peptidoglycan recognition protein 4 (PGLRP4), belongs to the family of human recognition molecules that bind peptidoglycan (a ubiquitous component of bacterial cell walls) and gram-positive bacteria as part of the innate immune response. It has N-acetylmuramoyl-L-alanine amidase activity and is primarily expressed in the esophagus, where it is thought to play a role in host antimicrobial defense. PGRP-I beta has two predicted transmembrane domains and extracellular N- and C-termini. The amino acid sequence of human PGRP- I beta is 99% and 76% identical to that of chimpanzee and mouse.

Long Name

Peptidoglycan Recognition Protein Intermediate, Beta/Peptidoglycan Recognition Protein 4

Alternate Names

Pglyrp-1 beta, PGRP-I beta, PGRPI beta

Entrez Gene IDs

57115 (Human)

Gene Symbol

PGLYRP4

UniProt

Q96LB8

Additional PGLYRP4/PGRP-I beta Products

Product Documents for Human PGLYRP4/PGRP‑I beta Antibody

Certificate of Analysis

To download a Certificate of Analysis, please enter a lot or batch number in the search box below.

Note: Certificate of Analysis not available for kit components.

Download SDS

Product Specific Notices for Human PGLYRP4/PGRP‑I beta Antibody

For research use only

Related Research Areas

Host Defense/Innate Immunity

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