Human Protein S/PROS1 Antibody Summary
Accession # P07225
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Detection of Human Protein S/PROS1 by Western Blot. Western blot shows human plasma. PVDF membrane was probed with 0.5 µg/mL of Mouse Anti-Human Protein S/PROS1 Monoclonal Antibody (Catalog # MAB4036) followed by HRP-conjugated Anti-Mouse IgG Secondary Antibody (Catalog # HAF018). A specific band was detected for Protein S/PROS1 at approximately 80 kDa (as indicated). This experiment was conducted under non-reducing conditions and using Immunoblot Buffer Group 1.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Background: Protein S/PROS1
The PROS1 gene encodes Protein S (PS), a ~70 kDa vitamin-K dependent plasma glycoprotein mainly synthesized by human hepatocytes. PS is a non-enzymatic cofactor in the degradation of coagulation factors Va and VIIIa and thus plays an anticoagulant role. Approximately 60% circulates in complex with C4b-binding protein. Free PS is a mixture of monomers and multimers. The 652 aa PS proprotein is heavily modified with 11 carboxyglutamates, one hydroxyaspartate, disulfides and glycosylation. Human Protein S shows 80% aa identity with mouse Protein S.
Citations for Human Protein S/PROS1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Alcohol and HIV-Derived Hepatocyte Apoptotic Bodies Induce Hepatic Stellate Cell Activation
Authors: M New-Aaron, RS Dagur, SS Koganti, M Ganesan, W Wang, E Makarov, M Ogunnaike, KK Kharbanda, LY Poluektova, NA Osna
Sample Types: Whole Cells
Human Placental Mesenchymal Stem/Stromal cells (pMSCs) inhibit agonist-induced platelet functions reducing atherosclerosis and thrombosis phenotypes
Authors: A Al Subayyi, YS Basmaeil, R Alenzi, T Khatlani
Journal of Cellular and Molecular Medicine, 2021;0(0):.
Sample Types: Cell Lysates
Applications: Western Blot
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