Human RAR alpha /NR1B1 Antibody

R&D Systems | Catalog # PP-H1920-00

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Key Product Details

Species Reactivity

Validated:

Human

Cited:

Human, Primate - Chlorocebus aethiops (African Green Monkey)

Applications

Validated:

Western Blot, Direct ELISA, Immunoprecipitation

Cited:

Chromatin Immunoprecipitation (ChIP), Bioassay

Label

Unconjugated

Antibody Source

Monoclonal Mouse IgG1 Clone # H1920
View all RAR alpha/NR1B1 Primary Antibodies »

Product Specifications

Immunogen

Recombinant human RAR alpha/NR1B1

Specificity

This antibody specifically recognizes human RAR alpha and does not cross-react with human RAR beta or RAR gamma. Not yet tested in other species.

Clonality

Monoclonal

Host

Mouse

Isotype

IgG1

Applications for Human RAR alpha /NR1B1 Antibody

Application
Recommended Usage

Direct ELISA

This antibody can be used at 0.2 μg/mL with the appropriate secondary reagents to detect human RAR alpha.

Immunoprecipitation

Optimal dilutions should be determined by each laboratory.

Western Blot

This antibody can be used at 1 μg/mL under reducing conditions and at 3 μg/mL under non-reducing conditions with the appropriate secondary reagents to detect human RAR alpha.

Formulation, Preparation, and Storage

Purification

Protein A or G purified from hybridoma culture supernatant

Formulation

A liquid formulation in physiologic saline with 0.1% NaN3.

Shipping

The product is shipped with dry ice or equivalent. Upon receipt, store it immediately at the temperature recommended below.

Stability & Storage

This antibody is stable for greater than six months when held at -20 °C in a manual defrost freezer or at -70 °C. Upon thawing, the antibody can be stored at 2-8 °C for at least 1 month without detectable loss of activity. Avoid repeated freeze-thaw cycles.

Background: RAR alpha/NR1B1

Retinoic Acid Receptor alpha (RAR alpha ; NR1B1) is closely related to the Thyroid hormone Receptor (TR). RARs bind to two retinoids, all-trans retinoic acid and 9-cis retinoic acid. RAR alpha is expressed in adult skin, and lung. RAR alpha is redundantly involved in vertebrates in the pleiotropic control of embryonic patterning and organogenesis, cell proliferation, differentiation and apoptosis, as well as homeostatic control.

Long Name

Retinoic Acid Receptor, alpha

Alternate Names

NR1B1, RARA

Entrez Gene IDs

5914 (Human)

Gene Symbol

RARA

Additional RAR alpha/NR1B1 Products

Product Documents for Human RAR alpha /NR1B1 Antibody

Certificate of Analysis

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Note: Certificate of Analysis not available for kit components.

Product Specific Notices for Human RAR alpha /NR1B1 Antibody

For research use only

Citations for Human RAR alpha /NR1B1 Antibody

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