Human SLC6A2/NET (NP_001034) VersaClone cDNA

Name: Human SLC6A2/NET (NP_001034) VersaClone cDNA
Brand: R&D Systems
SKU: RDC1112
Price: 675 USD
Availability: InStock

R&D Systems | Catalog # RDC1112

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Preparation & Storage
Background
Product Documents
Specific Notices

Key Product Details

Species

Human

Accession Number

NP_001034

Formulation, Preparation, and Storage

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.

Storage

Store the unopened product at -20 to -70 °C. Use a manual defrost freezer and avoid repeated freeze-thaw cycles. Do not use past expiration date.

Background: SLC6A2/NET

Norepinephrine Transporter [NET] (or noradrenaline transporter (NAT)) is a monoamine transporter that transports the neurotransmitter noradrenaline from the synapse back to its vesicles for storage until later use. It also appears to transport the neurotransmitter dopamine in the same way, but to a lesser degree. Studies have shown a decrease in NET levels in the locus coeruleus in patients diagnosed with major depression (Klimek et al., 1997). Cocaine, amphetamines and many therapeutic antidepressants, such as the SNRIs (Serotonin-norepinephrine reuptake inhibitors) and the tricyclic antidepressants (TCAs) act to raise noradrenaline. Furthermore, deficits in the NET gene have been associated with ADHD (Kim et al., 2006).

Long Name

Norepinephrine Transporter

Alternate Names

NAT1, Noradrenalin Transporter, Norepinephrine Transporter

Entrez Gene IDs

6530 (Human); 20538 (Mouse); 83511 (Rat)

Gene Symbol

SLC6A2

UniProt

NP_001034

Additional SLC6A2/NET Products

Product Documents for Human SLC6A2/NET (NP_001034) VersaClone cDNA

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Certificate of Analysis

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Product Specific Notices for Human SLC6A2/NET (NP_001034) VersaClone cDNA

For research use only

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