Human SLURP1 Antibody
Human SLURP1 Antibody Summary
Accession # P55000
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
SLURP1 (Secreted Ly6/uPAR-related protein 1; also ARS Component B and ANUP) is a 9-10 kDa secreted member of the Ly6/uPAR Superfamily of proteins. It is expressed by restricted cell types, including sensory neurons, ciliated bronchial epithelium, T and B cells, and stratified squamous epithelium of the skin, vagina and esophagus. SLURP1 binds to the alpha 7 nicotinic acetylcholine receptor, which suggests it regulates Ca and Na transport. This translates into reduced TNF alpha release by macrophages, and activation of select cellular caspases. Mature human SLURP1 is 82 amino acids (aa) in length (aa 22-103). It contains one UPAR/Ly6 domain (aa 24‑73), and forms noncovalent homodimers. Mature human SLURP1 shares 67% aa identity with mouse SLURP1.
Citation for Human SLURP1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
Expression microarray analysis identifies novel epithelial-derived protein markers in eosinophilic esophagitis.
Authors: Matoso, Andres, Mukkada, Vincent, Lu, Shaolei, Monahan, Renee, Cleveland, Kelly, Noble, Lelia, Mangray, Shamlal, Resnick, Murray B
Mod Pathol, 2013;26(5):665-76.
Sample Types: Whole Tissue
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