Human TREML1/TLT-1 Antibody
Human TREML1/TLT-1 Antibody Summary
Accession # Q86YW5
Complete Your Research
Complete Your Experiment
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
TREML1 is a type I transmembrane protein that differs from TREM in the cytoplasmic region by having two ITIMs (Immunoreceptor Tyrosine-based Inhibition Motif). A splice variant lacking ITIMs in its cytoplasmic domain also exists. TREML1 is found only in platelets and megakaryocytes. The extracellular region of human and mouse TREML1 share 75% amino acid sequence identity.
Citation for Human TREML1/TLT-1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
Inhibition of thrombin-induced platelet aggregation using human single-chain Fv antibodies specific for TREM-like transcript-1.
Authors: Giomarelli B, Washington VA, Chisholm MM, Quigley L, McMahon JB, Mori T, McVicar DW
Thromb. Haemost., 2007;97(6):955-63.
Sample Types: Cell Lysates
Applications: Western Blot
No product specific FAQs exist for this product, however you mayView all Antibody FAQs
Reviews for Human TREML1/TLT-1 Antibody
Average Rating: 5 (Based on 2 Reviews)
Have you used Human TREML1/TLT-1 Antibody?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image
Gated on lymphocyte FSC-A and SSC-A populations. Singlets were further gated on by FSC-A/FSC-H doublet exclusion. After primary antibody staining, cells were washED 2x and Alexa 488 labeled rabbit anti-goat IgG (1:200) was added for 20 min. Cells were washed 2x and fixed in orthofix. Isotype control shaded grey, TREML1 in open histogram.
Buffer: 2% FCS, 0.5 mM EDTA
Gated on monocytic FSC-A and SSC-A population. Singlets were further gated on by FSC-A/FSC-H doublet exclusion. After primary antibody staining, cells were washed 2x and Alexa 488 labeled rabbit anti-goat IgG (1:200) was added for 20 min. Cells were washed 2x and fixed in orthofix. Isotype control shaded grey, TREML1 in open histogram.
Buffer: 2% HS, 0.5 mM EDTA