Human VE-Statin Antibody

Catalog #: AF3638
3 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF3638
AF3638-SP

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Product Details

Citations (3)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Human VE-Statin Antibody Summary

Species Reactivity

Human

Specificity

Detects human VE-Statin in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse VE-Statin is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

E. coli-derived recombinant human VE-Statin
Glu21-Ser273
Accession # BAD01469

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Endotoxin Level

<0.10 EU per 1 μg of the antibody by the LAL method.

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Human VE-Statin

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available

Reconstitution Buffer 1 (PBS)

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: VE-Statin

VE-Statin, also known as epidermal growth factor-like domain 7 (EGFL7), is a secreted endothelial-specific protein that is a marker for progenitor, embryonic and adult endothelial cells. Mature soluble VE-Statin is a 41 kDa protein containing an N-terminal cysteine-rich EMI domain, followed by two EGF-like domains and a coiled-coil region. VE-Statin inhibits PDGF-BB-induced smooth muscle cell migration. The amino acid sequence of human VE-Statin is 80% identical to that of mouse VE-Statin.

Long Name

Vascular Endothelial Statin/EGF-like Domain, Multiple 7

Entrez Gene IDs

51162 (Human)

Alternate Names

EGFL7; EGF-like protein 7; EGF-like-domain, multiple 7; epidermal growth factor-like protein 7; MEGF7; MGC111117; Multiple EGF-like domains protein 7; Multiple epidermal growth factor-like domains protein 7; NEU1 protein; NOTCH4-like protein; RP11-251M1.2; Vascular endothelial statin; VEStatin; VE-Statin; ZNEU1

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Human VE-Statin Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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Epidermal Growth Factor Like-domain 7 and miR-126 are abnormally expressed in diffuse Systemic Sclerosis fibroblasts
Authors: V Liakouli, P Cipriani, P Di Benedet, N Panzera, P Ruscitti, I Pantano, O Berardicur, F Carubbi, F Esteves, G Mavria, F Del Galdo, R Giacomelli
Sci Rep, 2019;9(1):4589.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot
Endothelial Cell Activation is Regulated by Epidermal Growth Factor-Like Domain 7 (Egfl7) during Inflammation
J Biol Chem, 2016;0(0):.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot
VE-statin/egfl7 regulates vascular elastogenesis by interacting with lysyl oxidases.
Authors: Lelievre E, Hinek A, Lupu F, Buquet C, Soncin F, Mattot V
EMBO J., 2009;27(12):1658-70.
Species: Human
Sample Types: Whole Cells
Applications: ICC