Human VE-Statin Antibody

Catalog # Availability Size / Price Qty
AF3638
AF3638-SP
Product Details
Citations (3)
FAQs
Supplemental Products
Reviews

Human VE-Statin Antibody Summary

Species Reactivity
Human
Specificity
Detects human VE-Statin in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant mouse VE-Statin is observed.
Source
Polyclonal Goat IgG
Purification
Antigen Affinity-purified
Immunogen
E. coli-derived recombinant human VE-Statin
Glu21-Ser273
Accession # BAD01469
Formulation
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied as a 0.2 µm filtered solution in PBS.
Endotoxin Level
<0.10 EU per 1 μg of the antibody by the LAL method.

Applications

Recommended Concentration
Sample
Western Blot
0.1 µg/mL
Recombinant Human VE-Statin

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Preparation and Storage

Reconstitution
Reconstitute at 0.2 mg/mL in sterile PBS.
Reconstitution Buffer Available
Reconstitution Buffer 1 (PBS)
Catalog #
Availability
Size / Price
Qty
RB01
Shipping
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: VE-Statin

VE-Statin, also known as epidermal growth factor-like domain 7 (EGFL7), is a secreted endothelial-specific protein that is a marker for progenitor, embryonic and adult endothelial cells. Mature soluble VE-Statin is a 41 kDa protein containing an N-terminal cysteine-rich EMI domain, followed by two EGF-like domains and a coiled-coil region. VE-Statin inhibits PDGF-BB-induced smooth muscle cell migration. The amino acid sequence of human VE-Statin is 80% identical to that of mouse VE-Statin.

Long Name
Vascular Endothelial Statin/EGF-like Domain, Multiple 7
Entrez Gene IDs
51162 (Human)
Alternate Names
EGFL7; EGF-like protein 7; EGF-like-domain, multiple 7; epidermal growth factor-like protein 7; MEGF7; MGC111117; Multiple EGF-like domains protein 7; Multiple epidermal growth factor-like domains protein 7; NEU1 protein; NOTCH4-like protein; RP11-251M1.2; Vascular endothelial statin; VEStatin; VE-Statin; ZNEU1

Product Datasheets

Citations for Human VE-Statin Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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  1. Epidermal Growth Factor Like-domain 7 and miR-126 are abnormally expressed in diffuse Systemic Sclerosis fibroblasts
    Authors: V Liakouli, P Cipriani, P Di Benedet, N Panzera, P Ruscitti, I Pantano, O Berardicur, F Carubbi, F Esteves, G Mavria, F Del Galdo, R Giacomelli
    Sci Rep, 2019;9(1):4589.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  2. Endothelial Cell Activation is Regulated by Epidermal Growth Factor-Like Domain 7 (Egfl7) during Inflammation
    J Biol Chem, 2016;0(0):.
    Species: Human
    Sample Types: Cell Lysates
    Applications: Western Blot
  3. VE-statin/egfl7 regulates vascular elastogenesis by interacting with lysyl oxidases.
    Authors: Lelievre E, Hinek A, Lupu F, Buquet C, Soncin F, Mattot V
    EMBO J., 2009;27(12):1658-70.
    Species: Human
    Sample Types: Whole Cells
    Applications: ICC

FAQs

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Isotype Controls

Reconstitution Buffers

Secondary Antibodies

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