Mouse Exostosin-like 2/EXTL2 Lumenal Domain Antibody

Catalog #: AF2536 Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF2536
AF2536-SP

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Exostosin-like 2/EXTL2 Lumenal Domain Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Exostosin-like 2/EXTL2 Lumenal Domain in direct ELISAs and Western blots. In Western blots, less than 5% cross-reactivity with recombinant mouse EXTL1 and recombinant human EXTL3 is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse Exostosin-like 2/EXTL2 Lumenal Domain
Asn43-Met330
Accession # Q9ES89

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse Exostosin-like 2/EXTL2 Lumenal Domain

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available

Reconstitution Buffer 1 (PBS)

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Exostosin-like 2/EXTL2

EXTL2 is a type II golgi membrane protein with a C-terminal lumenal region that contains the catalytic domain. It is a glycosyl transferase that is required for the biosynthesis of heparan sulfate. The lumenal region of mouse EXTL2 shares 90% and 86% aa sequence identity with the canine and human proteins, respectively.

Entrez Gene IDs

2135 (Human); 58193 (Mouse)

Alternate Names

Alpha-1,4-N-acetylhexosaminyltransferase EXTL2; alpha-1,4-N-acteylhexosaminyltransferase; Alpha-GalNAcT EXTL2; EC 2.4.1.223; exostoses (multiple)-like 2; Exostosin like 2; Exostosin-like 2; EXTL2; EXTR2; EXT-related protein 2; Glucuronyl-galactosyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase; processed exostosin-like 2