Mouse FAM3B Antibody
Mouse FAM3B Antibody Summary
Accession # Q9D309
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
FAM3B, also known as Pancreatic-Derived factor (PANDER), is a secreted, monomeric, 23 kDa glycoprotein that belongs to a new family of four-helix bundle cytokines. It is highly expressed in pancreatic islet cells and reproductive epithelium. FAM3B has been shown to induce b-cell apoptosis and decrease insulin secretion. Two alternative N-termini, at Glu 30 and Ser 46, have been observed for mature FAM3B. The long version of mature mouse FAM3B shares 80%, 92%, and 75% amino acid sequence homology with the human, rat and canine mature FAM3B, respectively.
Citations for Mouse FAM3B Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
Citations: Showing 1 - 2
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Parkinson's disease and multiple system atrophy patient iPSC-derived oligodendrocytes exhibit alpha-synuclein-induced changes in maturation and immune reactive properties
Authors: C Azevedo, G Teku, Y Pomeshchik, JF Reyes, M Chumarina, K Russ, E Savchenko, A Hammarberg, NJ Lamas, A Collin, GK Gouras, O Klementiev, M Hallbeck, R Taipa, M Vihinen, L Roybon
Proceedings of the National Academy of Sciences of the United States of America, 2022;119(12):e2111405119.
Sample Types: Whole Cells
Upregulation of pancreatic derived factor (FAM3B) expression in pancreatic beta-cells by MCP-1 (CCL2).
Authors: Hou X, Wang O, Li Z, Mou H, Chen J, Deng B, Qian L, Liu X, Le Y
Mol. Cell. Endocrinol., 2011;343(1):18-24.
Sample Types: Cell Lysates
Applications: Western Blot
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