Mouse IGFBP-rP10 Antibody
Mouse IGFBP-rP10 Antibody Summary
Accession # NP_849260
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
IGFBP-rP10, also known as Kazal-type serine protease inhibitor domain-containing protein 1 and bone and odontoblast-expressed protein 1, belongs to the IFGBP superfamily. It is a 276 amino acid (aa) residue, 36 kDa secreted protein that contains an N-terminal IGFBP domain, a Kazal-type serine protease inhibitor region, a C2-type Ig-like domain and a C-terminal poly-glu segment. An alternate variant with a 16 aa substitution for the C-terminal 33 residues has also been reported. IGFBP‑rP10 is expressed in multiple tissues including osteoblasts/odontoblasts and is up-regulated during osteoblast differentiation and bone regeneration. Mouse mature IGFBP-rP10 shares 96% and 87% aa sequence identity with rat and human IGFBP-rP10, respectively.
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