Mouse IL-6 Quantikine ELISA Kit

Catalog # Availability Size / Price Qty
PM6000B
SM6000B
M6000B
IL-6 ELISA Kit ELISA
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Product Details
Citations (311)
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Mouse IL-6 Quantikine ELISA Kit Summary

Assay Length
4.5 hours
Sample Type & Volume Required Per Well
Cell Culture Supernates (50 uL), Serum (50 uL), Heparin Plasma (50 uL)
Sensitivity
1.8 pg/mL
Assay Range
7.8 - 500 pg/mL (Cell Culture Supernates, Serum, Heparin Plasma)
Specificity
Natural and recombinant mouse IL-6
Cross-reactivity
< 0.5% cross-reactivity observed with available related molecules.< 50% cross-species reactivity observed with species tested.
Interference
No significant interference observed with available related molecules.

Product Summary

The Quantikine Mouse IL-6 Immunoassay is a 4.5 hour solid-phase ELISA designed to measure mouse IL-6 in cell culture supernates, serum, and plasma. It contains E. coli-expressed recombinant mouse IL-6 and antibodies raised against the recombinant factor. This immunoassay has been shown to accurately quantitate the recombinant mouse IL-6. Results obtained using natural mouse IL-6 showed dose response curves that were parallel to the standard curves obtained using the Quantikine mouse kit standards. These results indicate that this kit can be used to determine relative mass values for natural mouse IL-6.

Precision

Intra-Assay Precision (Precision within an assay) Three samples of known concentration were tested on one plate to assess intra-assay precision
Inter-Assay Precision (Precision between assays) Three samples of known concentration were tested in separate assays to assess inter-assay precision

Cell Culture Supernates, Serum, Heparin Plasma

Intra-Assay Precision Inter-Assay Precision
Sample 1 2 3 1 2 3
n 20 20 20 28 22 27
Mean 30 87 232 29 85 238
Standard Deviation 2 3.4 8.1 1.8 7.5 18.1
CV% 6.7 3.9 3.5 6.1 8.9 7.6

Recovery

The recovery of mouse IL-6 spiked to three levels throughout the range of the assay in various matrices was evaluated.

Sample Type Average % Recovery Range %
Cell Culture Supernates (n=5) 110 86-120
Heparin Plasma (n=6) 101 81-115
Serum (n=5) 99 84-113

Linearity

To assess the linearity of the assay, samples containing and/or spiked with high concentrations of mouse IL-6 were serially diluted with Calibrator Diluent to produce samples with values within the dynamic range of the assay.
Mouse IL-6 ELISA Linearity

Data Examples

Mouse IL-6 ELISA Standard Curve

Product Datasheets

Preparation and Storage

Storage
Store the unopened product at 2 - 8 °C. Do not use past expiration date.

Background: IL-6

Interleukin 6 (IL-6) is a pleiotropic, a-helical, 22-28 kDa phosphorylated and variably glycosylated cytokine that plays important roles in the acute phase reaction, inflammation, hematopoiesis, bone metabolism, and cancer progression. Mature human IL-6 is 183 amino acids (aa) in length and shares 39% aa sequence identity with mouse and rat IL-6. Alternative splicing generates several isoforms with internal deletions, some of which exhibit antagonistic properties. Cells known to express IL-6 include CD8+ T cells, fibroblasts, synoviocytes, adipocytes, osteoblasts, megakaryocytes, endothelial cells (under the influence of endothelins), sympathetic neurons, cerebral cortex neurons, adrenal medulla chromaffin cells, retinal pigment cells, mast cells, keratinocytes, Langerhans cells, fetal and adult astrocytes, neutrophils, monocytes, eosinophils, colonic epithelial cells, B1 B cells and pancreatic islet beta cells. IL-6 production is generally correlated with cell activation and is normally kept in control by glucocorticoids, catecholamines, and secondary sex steroids. Normal human circulating IL-6 is in the 1 pg/mL range, with slight elevations during the menstrual cycle, modest elevations in certain cancers, and large elevations after surgery.

IL-6 induces signaling through a cell surface heterodimeric receptor complex composed of a ligand binding subunit (IL-6 R alpha) and a signal transducing subunit (gp130). IL-6 binds to IL-6 Ra, triggering IL-6 Ra association with gp130 and gp130 dimerization. gp130 is also a component of the receptors for CLC, CNTF, CT-1, IL-11, IL-27, LIF, and OSM. Soluble forms of IL-6 Ra are generated by both alternative splicing and proteolytic cleavage. In a mechanism known as trans-signaling, complexes of soluble IL-6 and IL-6 Ra elicit responses from gp130-expressing cells that lack cell surface IL-6 Ra. Trans-signaling enables a wider range of cell types to respond to IL-6, as the expression of gp130 is ubiquitous, while that of IL-6 Ra is predominantly restricted to hepatocytes, monocytes, and resting lymphocytes. Soluble splice forms of gp130 block trans-signaling from IL-6/IL-6 Ra but not from other cytokines that use gp130 as a co-receptor.

IL-6, along with TNF-a and IL-1, drives the acute inflammatory response. IL-6 is almost solely responsible for fever and the acute phase response in the liver, and it is important in the transition from acute inflammation to either acquired immunity or chronic inflammatory disease. When dysregulated, it contributes to chronic inflammation in conditions such as obesity, insulin resistance, inflammatory bowel disease, arthritis, and sepsis. IL-6 modulates bone resorption and is a major effector of inflammatory joint destruction in rheumatoid arthritis through its promotion of Th17 cell development and activity. It contributes to atherosclerotic plaque development and destabilization as well as the development of inflammation-associated carcinogenesis.

Long Name:
Interleukin 6
Entrez Gene IDs:
3569 (Human); 16193 (Mouse); 24498 (Rat); 399500 (Porcine); 280826 (Bovine); 403985 (Canine); 100034196 (Equine); 493687 (Feline); 463288 (Primate); 100008733 (Rabbit)
Alternate Names:
B cell stimulatory factor-2; B-cell differentiation factor; BSF-2; BSF2CTL differentiation factor; CDF; HGFHSFIFNB2Hybridoma growth factor; IFN-beta-2; IL6; IL-6; IL-6B-cell stimulatory factor 2; Interferon beta-2; interleukin 6 (interferon, beta 2); interleukin BSF-2; interleukin-6; MGI-2A
⚠ WARNING: This product can expose you to chemicals including N,N-Dimethylforamide, which is known to the State of California to cause cancer. For more information, go to www.P65Warnings.ca.gov.

Citations for Mouse IL-6 Quantikine ELISA Kit

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

311 Citations: Showing 1 - 10
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  1. miR-146a targeted to splenic macrophages prevents sepsis-induced multiple organ injury
    Authors: Y Funahashi, N Kato, T Masuda, F Nishio, H Kitai, T Ishimoto, T Kosugi, N Tsuboi, N Matsuda, S Maruyama, K Kadomatsu
    Lab. Invest., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  2. Dendritic cells modulate c-kit expression on the edge between activation and death
    Authors: S Simonetti, ABB Seijas, A Natalini, S Vitale, D Runci, A Soriani, A Di Virgili, E Aricò, L Gabriele, A Santoni, F Di Rosa
    Eur. J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  3. Costunolide alleviates HKSA-induced acute lung injury via inhibition of macrophage activation
    Authors: YT Chen, Y Du, B Zhao, LX Gan, KK Yu, L Sun, J Wang, F Qian
    Acta Pharmacol. Sin., 2019;0(0):.
    Species: Mouse
    Sample Types: BALF
  4. miR?155 mediates inflammatory injury of hippocampal neuronal cells via the activation of microglia
    Authors: XH Sun, MF Song, HD Song, YW Wang, MJ Luo, LM Yin
    Mol Med Rep, 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  5. Tofacitinib enhances delivery of antibody-based therapeutics to tumor cells through modulation of inflammatory cells
    Authors: N Simon, A Antignani, SM Hewitt, M Gadina, C Alewine, D FitzGerald
    JCI Insight, 2019;0(0):.
    Species: Mouse
    Sample Types: Serum
  6. Induced Pluripotent Stem Cells Regulate TREM-1 Expression and the p38 MAPK Pathway in Endotoxin-Induced Acute Lung Injury
    Authors: VY Su, KY Yang, SH Chiou, NJ Chen, MH Mo, CS Lin, CT Wang
    Stem Cells, 2019;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  7. Overexpression of SOCS3 mediated by adenovirus vector in mouse and human castration-resistant prostate cancer cells increases the sensitivity to NK cells in vitro and in vivo
    Authors: T Yoneda, N Kunimura, K Kitagawa, Y Fukui, H Saito, K Narikiyo, M Ishiko, N Otsuki, KI Nibu, M Fujisawa, S Serada, T Naka, T Shirakawa
    Cancer Gene Ther., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  8. Microbubble-mediated delivery of human adenoviruses does not elicit innate and adaptive immunity response in an immunocompetent mouse model of prostate cancer
    Authors: F De Carlo, L Thomas, B Brooke, ET Varney, R Nande, O Boskovic, GD Marshall, PP Claudio, CM Howard
    J Transl Med, 2019;17(1):19.
    Species: Mouse
    Sample Types: Serum
  9. Tissue-type plasminogen activator neutralizes LPS but not protease-activated receptor-mediated inflammatory responses to plasmin
    Authors: C Zalfa, P Azmoon, E Mantuano, SL Gonias
    J. Leukoc. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  10. Topical essential fatty acid oil on wounds: Local and systemic effects
    Authors: BG Lania, J Morari, AR Almeida, MND Silva, G Vieira-Dam, KA Lins, CL César, LA Velloso, NB Maia, ML Cintra, PENF Velho
    PLoS ONE, 2019;14(1):e0210059.
    Species: Mouse
    Sample Types: Serum
  11. The anticancer peptide RT53 induces immunogenic cell death
    Authors: E Pasquereau, J Habault, G Kroemer, JL Poyet
    PLoS ONE, 2018;13(8):e0201220.
    Species: Mouse
    Sample Types: Serum
  12. MTOR Suppresses Environmental Particle-Induced Inflammatory Response in Macrophages
    Authors: Z Li, Y Wu, H Chen, C Zhu, L Dong, Y Wang, H Liu, X Xu, J Zhou, Y Wu, W Li, S Ying, H Shen, Z Chen
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
  13. Antenatal IL-1-dependent inflammation persists postnatally and causes retinal and sub-retinal vasculopathy in progeny
    Authors: A Beaudry-Ri, M Nadeau-Val, É Prairie, N Maurice, É Heckel, M Nezhady, S Pundir, A Madaan, A Boudreault, X Hou, C Quiniou, EM Sierra, A Beaulac, G Lodygensky, SA Robertson, J Keelan, K Adams-Wald, DM Olson, JC Rivera, WD Lubell, JS Joyal, JF Bouchard, S Chemtob
    Sci Rep, 2018;8(1):11875.
    Species: Mouse
    Sample Types: Tissue Homogenates
  14. Perioperative use of cefazolin ameliorates postoperative cognitive dysfunction but induces gut inflammation in mice
    Authors: P Liang, W Shan, Z Zuo
    J Neuroinflammation, 2018;15(1):235.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  15. Therapeutic Effects of Systemic Administration of the Novel RANKL-Modified Peptide, MHP1, for Ischemic Stroke in Mice
    Authors: M Shimamura, H Nakagami, H Shimizu, K Wakayama, T Kawano, Y Ikeda, H Hayashi, S Yoshida, H Mochizuki, R Morishita
    Biomed Res Int, 2018;2018(0):4637084.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  16. Altered exocrine function can drive adipose wasting in early pancreatic cancer
    Authors: LV Danai, A Babic, MH Rosenthal, EA Dennstedt, A Muir, EC Lien, JR Mayers, K Tai, AN Lau, P Jones-Sali, CM Prado, GM Petersen, N Takahashi, M Sugimoto, JJ Yeh, N Lopez, N Bardeesy, C Fernandez-, AS Liss, AC Koong, J Bui, C Yuan, MW Welch, LK Brais, MH Kulke, C Dennis, CB Clish, BM Wolpin, MG Vander Hei
    Nature, 2018;558(7711):600-604.
    Species: Mouse
    Sample Types: Plasma
  17. CR6 interacting factor 1 deficiency promotes endothelial inflammation by SIRT1 downregulation
    Authors: S Piao, JW Lee, H Nagar, SB Jung, S Choi, S Kim, I Lee, SM Kim, N Shin, YR Lee, SD Lee, JB Park, K Irani, M Won, GM Hur, BH Jeon, DW Kim, CS Kim
    PLoS ONE, 2018;13(2):e0192693.
    Species: Mouse
    Sample Types: Plasma
  18. LncRNA GAS5 Overexpression Reverses LPS-Induced Inflammatory Injury and Apoptosis Through Up-Regulating KLF2 Expression in ATDC5 Chondrocytes
    Authors: F Li, J Sun, S Huang, G Su, G Pi
    Cell. Physiol. Biochem., 2018;45(3):1241-1251.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  19. Ginkgo biloba extracts prevent aortic rupture in angiotensin II-infused hypercholesterolemic mice
    Authors: XF Huang, SZ Zhang, YY You, N Zhang, H Lu, A Daugherty, XJ Xie
    Acta Pharmacol. Sin., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  20. Infection perturbs Bach2- and Bach1-dependent erythroid lineage 'choice' to cause anemia
    Authors: H Kato, A Itoh-Nakad, M Matsumoto, Y Ishii, M Watanabe-M, M Ikeda, R Ebina-Shib, Y Sato, M Kobayashi, H Nishizawa, K Suzuki, A Muto, T Fujiwara, Y Nannya, L Malcovati, M Cazzola, S Ogawa, H Harigae, K Igarashi
    Nat. Immunol., 2018;19(10):1059-1070.
    Species: Mouse
    Sample Types: Serum
  21. Adipocyte-specific expression of C-type natriuretic peptide suppresses lipid metabolism and adipocyte hypertrophy in adipose tissues in mice fed high-fat diet
    Authors: CR Bae, J Hino, H Hosoda, C Son, H Makino, T Tokudome, T Tomita, K Hosoda, M Miyazato, K Kangawa
    Sci Rep, 2018;8(1):2093.
    Species: Mouse
    Sample Types: Serum
  22. Prion protein protects mice from lethal infection with influenza A viruses
    Authors: J Chida, H Hara, M Yano, K Uchiyama, NR Das, E Takahashi, H Miyata, Y Tomioka, T Ito, H Kido, S Sakaguchi
    PLoS Pathog., 2018;14(5):e1007049.
    Species: Mouse
    Sample Types: Tissue Homogenates
  23. Salidroside prevents skin carcinogenesis induced by DMBA/TPA in a mouse model through suppression of inflammation and promotion of apoptosis
    Authors: YH Kong, SP Xu
    Oncol. Rep., 2018;0(0):.
    Species: Human
    Sample Types: Serum
  24. LLC tumor cells-derivated factors reduces adipogenesis in co-culture system
    Authors: MA Lopes, F Oliveira F, F Henriques, SB Peres, ML Batista
    Heliyon, 2018;4(7):e00708.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  25. Inhibition of nuclear factor of activated T cells (NFAT) c3 activation attenuates acute lung injury and pulmonary edema in murine models of sepsis
    Authors: M Karpurapu, YG Lee, Z Qian, J Wen, MN Ballinger, L Rusu, S Chung, J Deng, F Qian, BF Reader, TS Nirujogi, GY Park, D Pei, JW Christman
    Oncotarget, 2018;9(12):10606-10620.
    Species: Mouse
    Sample Types: BALF
  26. Inflammatory response of microglia to prions is controlled by sialylation of PrPSc
    Authors: S Srivastava, E Katorcha, N Makarava, JP Barrett, DJ Loane, IV Baskakov
    Sci Rep, 2018;8(1):11326.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  27. Regulation of the NLRP3 inflammasome and macrophage pyroptosis by the p38 MAPK signaling pathway in a mouse model of acute lung injury
    Authors: D Li, W Ren, Z Jiang, L Zhu
    Mol Med Rep, 2018;0(0):.
    Species: Mouse
    Sample Types: BALF
  28. JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents depression-associated behaviors induced by chronic social defeat stress
    Authors: X Zhu, MT Nedelcovyc, AG Thomas, Y Hasegawa, A Moreno-Meg, W Coomer, V Vohra, A Saito, G Perez, Y Wu, J Alt, E Prchalova, L Tenora, P Majer, R Rais, C Rojas, BS Slusher, A Kamiya
    Neuropsychopharmacology, 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  29. A Novel Peroxidase Mimics and Ameliorates Alzheimer's Disease-Related Pathology and Cognitive Decline in Mice
    Authors: J Xu, K Wang, Y Yuan, H Li, R Zhang, S Guan, L Wang
    Int J Mol Sci, 2018;19(11):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  30. ?-Synuclein disrupts the anti-inflammatory role of Drd2 via interfering ?-arrestin2-TAB1 interaction in astrocytes
    Authors: RH Du, Y Zhou, ML Xia, M Lu, JH Ding, G Hu
    J Neuroinflammation, 2018;15(1):258.
    Species: Mouse
    Sample Types: Tissue Homogenate
  31. Critical Adverse Impact of IL-6 in Acute Pneumovirus Infection
    Authors: CM Percopo, M Ma, TA Brenner, JO Krumholz, TJ Break, K Laky, HF Rosenberg
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Serum
  32. Nitric Oxide Is Involved in Activation of Toll-Like Receptor 4 Signaling through Tyrosine Nitration of Src Homology Protein Tyrosine Phosphatase 2 in Murine Dextran Sulfate-Induced Colitis
    Authors: X Tun, K Yasukawa, KI Yamada
    Biol. Pharm. Bull., 2018;41(12):1843-1852.
    Species: Mouse
    Sample Types: Cell Lysates
  33. Development of a novel RANKL-based peptide, microglial healing peptide1-AcN (MHP1-AcN), for treatment of ischemic stroke
    Authors: M Shimamura, H Nakagami, H Shimizu, H Mukai, R Watanabe, T Okuzono, T Kawano, Y Ikeda, H Hayashi, S Yoshida, N Ju, H Mochizuki, R Morishita
    Sci Rep, 2018;8(1):17770.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  34. SLC15A2 and SLC15A4 Mediate the Transport of Bacterially Derived Di/Tripeptides To Enhance the Nucleotide-Binding Oligomerization Domain-Dependent Immune Response in Mouse Bone Marrow-Derived Macrophages
    Authors: Y Hu, F Song, H Jiang, G Nuñez, DE Smith
    J. Immunol., 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  35. Targeting miR-223 in neutrophils enhances the�clearance of Staphylococcus aureus in infected�wounds
    Authors: M de Kerckho, K Tanaka, T Umehara, M Okamoto, S Kanematsu, H Hayashi, H Yano, S Nishiura, S Tooyama, Y Matsubayas, T Komatsu, S Park, Y Okada, R Takahashi, Y Kawano, T Hanawa, K Iwasaki, T Nozaki, H Torigoe, K Ikematsu, Y Suzuki, K Tanaka, P Martin, I Shimokawa, R Mori
    EMBO Mol Med, 2018;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  36. The anti-inflammatory action of maropitant in a mouse model of acute pancreatitis
    Authors: A Tsukamoto, M Ohgoda, N Haruki, M Hori, T Inomata
    J. Vet. Med. Sci., 2018;0(0):.
    Species: Mouse
    Sample Types: Plasma
  37. Endothelial cell-specific anticoagulation reduces inflammation in a mouse model of acute lung injury
    Authors: J Lou, Y Hu, MD Wu, LQ Che, YF Wu, Y Zhao, BP Tian, ZQ Bao, C Zhu, YP Wu, LL He, CX Bai, J Zhou, SM Ying, W Li, ZH Chen, DX Chen, A Dorling, HH Shen
    Acta Pharmacol. Sin., 2018;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenate
  38. Impact of Acetazolamide, a Carbonic Anhydrase Inhibitor, on the Development of Intestinal Polyps in Min Mice
    Authors: N Noma, G Fujii, S Miyamoto, M Komiya, R Nakanishi, M Shimura, SI Tanuma, M Mutoh
    Int J Mol Sci, 2017;18(4):.
    Species: Mouse
    Sample Types: Serum
  39. ACVR2B/Fc counteracts chemotherapy-induced loss of muscle and bone mass
    Authors: R Barreto, Y Kitase, T Matsumoto, F Pin, KC Colston, KE Couch, TM O'Connell, ME Couch, LF Bonewald, A Bonetto
    Sci Rep, 2017;7(1):14470.
    Species: Mouse
    Sample Types: Plasma
  40. Para-hydroxyphenylpyruvate inhibits the pro-inflammatory stimulation of macrophage preventing LPS-mediated nitro-oxidative unbalance and immunometabolic shift
    Authors: R Scrima, M Menga, C Pacelli, F Agriesti, O Cela, C Piccoli, A Cotoia, A De Gregori, JV Gefter, G Cinnella, N Capitanio
    PLoS ONE, 2017;12(11):e0188683.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  41. The Synthetic Lignan Secoisolariciresinol Diglucoside Prevents Asbestos-Induced NLRP3 Inflammasome Activation in Murine Macrophages
    Authors: RA Pietrofesa, P Woodruff, WT Hwang, P Patel, S Chatterjee, SM Albelda, M Christofid
    Oxid Med Cell Longev, 2017;2017(0):7395238.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  42. Circulating soluble endoglin modifies the inflammatory response in mice
    Authors: L Ruiz-Remol, C Ollauri-Ib, L Pérez-Roqu, E Núñez-Góme, F Pérez-Barr, JM López-Novo, M Pericacho, A Rodríguez-
    PLoS ONE, 2017;12(11):e0188204.
    Species: Mouse
    Sample Types: Plasma
  43. Epithelial Fli1 deficiency drives systemic autoimmunity and fibrosis: Possible roles in scleroderma
    Authors: T Takahashi, Y Asano, K Sugawara, T Yamashita, K Nakamura, R Saigusa, Y Ichimura, T Toyama, T Taniguchi, K Akamata, S Noda, A Yoshizaki, D Tsuruta, M Trojanowsk, S Sato
    J. Exp. Med, 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  44. The Effect of Low-Dose Proteasome Inhibition on Pre-Existing Atherosclerosis in LDL Receptor-Deficient Mice
    Authors: N Wilck, M Fechner, C Dan, V Stangl, K Stangl, A Ludwig
    Int J Mol Sci, 2017;18(4):.
    Species: Mouse
    Sample Types: Serum
  45. Endosomal NOX2 oxidase exacerbates virus pathogenicity and is a target for antiviral therapy
    Authors: EE To, R Vlahos, R Luong, ML Halls, PC Reading, PT King, C Chan, GR Drummond, CG Sobey, BRS Broughton, MR Starkey, R van der Sl, SR Lewin, S Bozinovski, LAJ O'Neill, T Quach, CJH Porter, DA Brooks, JJ O'Leary, S Selemidis
    Nat Commun, 2017;8(1):69.
    Species: Mouse
    Sample Types: BALF
  46. Protective Efficacy of the Trivalent Pseudomonas aeruginosa Vaccine Candidate PcrV-OprI-Hcp1 in Murine Pneumonia and Burn Models
    Authors: F Yang, J Gu, L Yang, C Gao, H Jing, Y Wang, H Zeng, Q Zou, F Lv, J Zhang
    Sci Rep, 2017;7(1):3957.
    Species: Mouse
    Sample Types: BALF
  47. Modifying Antigen-Encapsulating Liposomes with KALA Facilitates MHC Class I Antigen Presentation and Enhances Anti-tumor Effects
    Authors: N Miura, H Akita, N Tateshita, T Nakamura, H Harashima
    Mol. Ther, 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  48. In vivo biomarker analysis of intranasally dosed PC945, a novel antifungal triazole, on Aspergillus fumigatus infection in immunocompromised mice
    Authors: G Kimura, T Nakaoki, T Colley, G Rapeport, P Strong, K Ito, Y Kizawa
    Antimicrob. Agents Chemother., 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  49. The Orphan Nuclear Receptor NR4A3 Is Involved in the Function of Dendritic Cells
    Authors: M Nagaoka, T Yashiro, Y Uchida, T Ando, M Hara, H Arai, H Ogawa, K Okumura, K Kasakura, C Nishiyama
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  50. The nuclear factor-erythroid 2-related factor/heme oxygenase-1 axis is critical for the inflammatory features of type 2 diabetes-associated osteoarthritis
    Authors: C Vaamonde-G, A Courties, A Pigenet, MC Laiguillon, A Sautet, X Houard, S Kerdine-Rö, R Meijide, F Berenbaum, J Sellam
    J. Biol. Chem., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  51. The RB-IL-6 axis controls self-renewal and endocrine therapy resistance by fine-tuning mitochondrial activity
    Authors: S Kitajima, A Yoshida, S Kohno, F Li, S Suzuki, N Nagatani, Y Nishimoto, N Sasaki, H Muranaka, Y Wan, TC Thai, N Okahashi, F Matsuda, H Shimizu, T Nishiuchi, Y Suzuki, K Tominaga, N Gotoh, M Suzuki, ME Ewen, DA Barbie, O Hirose, T Tanaka, C Takahashi
    Oncogene, 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  52. Regulation of Arthritis Severity by the Acid Sphingomyelinase
    Authors: N Beckmann, KA Becker, S Walter, JU Becker, M Kramer, G Hessler, S Weber, JR Göthert, K Fassbender, E Gulbins, A Carpinteir
    Cell. Physiol. Biochem., 2017;43(4):1.
    Species: Mouse
    Sample Types: Tissue Homogenates
  53. Over-expressing the soluble gp130-Fc does not ameliorate methionine and choline deficient diet-induced non alcoholic steatohepatitis in mice
    Authors: HL Kammoun, TL Allen, DC Henstridge, MJ Kraakman, L Peijs, S Rose-John, MA Febbraio
    PLoS ONE, 2017;12(6):e0179099.
    Species: Mouse
    Sample Types: Plasma
  54. TDAG8, TRPV1, and ASIC3 involved in establishing hyperalgesic priming in experimental rheumatoid arthritis
    Authors: WS Hsieh, CC Kung, SL Huang, SC Lin, WH Sun
    Sci Rep, 2017;7(1):8870.
    Species: Mouse
    Sample Types: Serum
  55. A Phosphoproteomic Screen Identifies a Guanine Nucleotide Exchange Factor for Rab3A Protein as a Mitogen-activated Protein (MAP) Kinase Phosphatase-5-regulated MAP Kinase Target in Interleukin 6 (IL-6) Secretion and Myogenesis
    Authors: H Lee, K Min, JS Yi, H Shi, W Chang, L Jackson, AM Bennett
    J. Biol. Chem, 2017;292(9):3581-3590.
    Species: Mouse
    Sample Types: Serum
  56. Paradoxical Suppression of Atherosclerosis in the Absence of microRNA-146a
    Authors: HS Cheng, R Besla, A Li, Z Chen, EA Shikatani, M Nazari-Jah, A Hammoutène, MA Nguyen, M Geoffrion, L Cai, N Khyzha, T Li, SA MacParland, M Husain, MI Cybulsky, CM Boulanger, RE Temel, A Schober, KJ Rayner, C Robbins, JE Fish
    Circ. Res., 2017;0(0):.
  57. Hepatocyte-specific Smad7 deletion accelerates DEN-induced HCC via activation of STAT3 signaling in mice
    Authors: T Feng, J Dzieran, X Yuan, A Dropmann, T Maass, A Teufel, S Marhenke, T Gaiser, F Rückert, I Kleiter, S Kanzler, MP Ebert, A Vogel, P Ten Dijke, S Dooley, NM Meindl-Bei
    Oncogenesis, 2017;6(1):e294.
    Species: Mouse
    Sample Types: Serum
  58. Ginsenoside Rb1 Attenuates Isoflurane/surgery-induced Cognitive Dysfunction via Inhibiting Neuroinflammation and Oxidative Stress
    Authors: HH Miao, Y Zhang, GN Ding, FX Hong, P Dong, M Tian
    Biomed. Environ. Sci., 2017;30(5):363-372.
    Species: Mouse
    Sample Types: Tissue Homogenates
  59. Quercetin Protects Obesity-Induced Hypothalamic Inflammation by Reducing Microglia-Mediated Inflammatory Responses via HO-1 Induction
    Authors: J Yang, CS Kim, TH Tu, MS Kim, T Goto, T Kawada, MS Choi, T Park, MK Sung, JW Yun, SY Choe, JH Lee, Y Joe, HS Choi, SH Back, HT Chung, R Yu
    Nutrients, 2017;9(7):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  60. Antioxidant, anti-inflammatory and anti-septic potential of phenolic acids and flavonoid fractions isolated from Lolium multiflorum
    Authors: Ki-Choon Choi
    Pharm Biol, 2017;55(1):611-619.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  61. Autoantibody-induced internalization of CNS AQP4 water channel and EAAT2 glutamate transporter requires astrocytic Fc receptor
    Authors: SR Hinson, IC Clift, N Luo, TJ Kryzer, VA Lennon
    Proc. Natl. Acad. Sci. U.S.A., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  62. B Cell Homeostasis and Functional Properties Are Altered in an Hypochlorous Acid-Induced Murine Model of Systemic Sclerosis
    Authors: S Sanges, M Jendoubi, N Kavian, C Hauspie, S Speca, JC Crave, T Guerrier, G Lefèvre, V Sobanski, A Savina, E Hachulla, PY Hatron, M Labalette, F Batteux, S Dubucquoi, D Launay
    Front Immunol, 2017;8(0):53.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  63. Cytoplasmic Linker Protein CLIP170 Negatively Regulates TLR4 Signaling by Targeting the TLR Adaptor Protein TIRAP
    Authors: P Jakka, B Bhargavi, S Namani, S Murugan, G Splitter, G Radhakrish
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  64. Cigarette Smoke Impairs A2A Adenosine Receptor Mediated Wound Repair through Up-regulation of Duox-1 Expression
    Authors: Z Tian, H Zhang, J Dixon, N Traphagen, TA Wyatt, K Kharbanda, S Simet Chad, N Kolliputi, DS Allen-Gips
    Sci Rep, 2017;7(0):44405.
  65. Two novel roles of buffalo milk lactoperoxidase, antibiofilm agent and immunomodulator against multidrug resistant Salmonella enterica serovar Typhi and Listeria monocytogenes
    Authors: L Mahdi, H Musafer, L Zwain, I Salman, I Al-Joofy, K Rasool, A Mussa, S Al-Kakei, R Al-Oqaili, S Al-Alak, A Chaloob, A Abdulkaree, B Hussein, N Mahdi, N Taher
    Microb. Pathog., 2017;0(0):.
    Species: Mouse
    Sample Types: Serum
  66. Protective effect of Cl-amidine against CLP-induced lethal septic shock in mice
    Sci Rep, 2016;6(0):36696.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  67. Kruppel-like factor 6 promotes macrophage-mediated inflammation by suppressing B cell leukemia/lymphoma 6 expression
    J Biol Chem, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  68. Microenvironment-dependent growth of preneoplastic and malignant plasma cells in humanized mice
    Authors: R Das, T Strowig, R Verma, S Koduru, A Hafemann, S Hopf, MH Kocoglu, C Borsotti, L Zhang, A Branagan, E Eynon, MG Manz, RA Flavell, MV Dhodapkar
    Nat. Med., 2016;22(11):1351-1357.
    Species: Mouse
    Sample Types: Serum
  69. KLHDC10 Deficiency Protects Mice against TNF?-Induced Systemic Inflammation
    PLoS ONE, 2016;11(9):e0163118.
    Species: Mouse
    Sample Types: Serum
  70. CF Lung Infection and Inflammation: IL-17 Pathophysiology and Therapeutic Intervention
    Authors: Daniel Hsu
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: BALF
  71. Growth and metastasis of lung adenocarcinoma is potentiated by BMP4-mediated immunosuppression
    Authors: Limo Chen
    Oncoimmunology, 2016;5(11):e1234570.
    Species: Mouse
    Sample Types: Tissue Homogenates
  72. Intravenous hMSCs Ameliorate Acute Pancreatitis in Mice via Secretion of Tumor Necrosis Factor-? Stimulated Gene/Protein 6
    Sci Rep, 2016;6(0):38438.
    Species: Mouse
    Sample Types: Serum
  73. Leptin Production by Encapsulated Adipocytes Increases Brown Fat, Decreases Resistin, and Improves Glucose Intolerance in Obese Mice
    Authors: DJ DiSilvestr, E Melgar-Ber, R Yasmeen, P Fadda, LJ Lee, A Kalyanasun, CL Gilor, O Ziouzenkov
    PLoS ONE, 2016;11(4):e0153198.
    Species: Mouse
    Sample Types: Plasma
  74. The H3K9 methyltransferase Setdb1 regulates TLR4-mediated inflammatory responses in macrophages
    Sci Rep, 2016;6(0):28845.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  75. Metformin preconditioned adipose derived mesenchymal stem cells is a better option for the reversal of diabetes upon transplantation
    Authors: Ramesh R Bhonde
    Biomed. Pharmacother., 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  76. Pancreatic stellate cell secreted IL-6 stimulates STAT3 dependent invasiveness of pancreatic intraepithelial neoplasia and cancer cells
    Authors: NS Nagathihal, JA Castellano, MN VanSaun, X Dai, M Ambrose, Q Guo, Y Xiong, NB Merchant
    Oncotarget, 2016;7(40):65982-65992.
    Species: Mouse
    Sample Types: Serum
  77. Early-onset obesity dysregulates pulmonary adipocytokine/insulin signaling and induces asthma-like disease in mice
    Authors: K Dinger, P Kasper, E Hucklenbru, C Vohlen, E Jobst, R Janoschek, I Bae-Gartz, S van Koning, C Plank, J Dötsch, MA Alejandre
    Sci Rep, 2016;6(0):24168.
    Species: Mouse
    Sample Types: Serum
  78. Effects of the stem extracts of Schisandra glaucescens Diels on collagen-induced arthritis in Balb/c mice
    Authors: Jinbo Fang
    J Ethnopharmacol, 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  79. Toll-like Receptor 4 Agonistic Antibody Promotes Host Defense against Chronic Pseudomonas aeruginosa Lung Infection in Mice
    Authors: S Nakamura, N Iwanaga, M Seki, K Fukudome, K Oshima, T Miyazaki, K Izumikawa, K Yanagihara, Y Miyazaki, H Mukae, S Kohno
    Infect Immun, 2016;0(0):.
    Species: Mouse
    Sample Types: Tissue Homogenates
  80. Subtilisin-like protease-1 secreted through type IV secretion system contributes to high virulence of Streptococcus suis 2
    Authors: Supeng Yin
    Sci Rep, 2016;6(0):27369.
    Species: Mouse
    Sample Types: Serum
  81. Laquinimod rescues striatal, cortical and white matter pathology and results in modest behavioural improvements in the YAC128 model of Huntington disease
    Sci Rep, 2016;6(0):31652.
    Species: Mouse
    Sample Types: Serum
  82. Ultrapure laser-synthesized Si-based nanomaterials for biomedical applications: in vivo assessment of safety and biodistribution
    Sci Rep, 2016;6(0):25400.
    Species: Mouse
    Sample Types: Serum
  83. Soluble Vascular Cell Adhesion Molecule-1 (VCAM-1) as a Biomarker in the Mouse Model of Experimental Autoimmune Myocarditis (EAM)
    PLoS ONE, 2016;11(8):e0158299.
    Species: Mouse
    Sample Types: Tissue Homogenates
  84. DNMT1-PPAR? pathway in macrophages regulates chronic inflammation and atherosclerosis development in mice
    Sci Rep, 2016;6(0):30053.
    Species: Mouse
    Sample Types: Plasma
  85. The Phosphocarrier Protein HPr Contributes to Meningococcal Survival during Infection
    PLoS ONE, 2016;11(9):e0162434.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  86. Systemic IL-6 Effector Response in Mediating Systemic Bone Loss Following Inhalation of Organic Dust
    Authors: Jill A Poole
    J. Interferon Cytokine Res., 2016;0(0):.
    Species: Mouse
    Sample Types: BALF
  87. Anti-tumor effects of (1?3)-?-d-glucan from Saccharomyces cerevisiae in S180 tumor-bearing mice
    Authors: Yong Zhan
    Int. J. Biol. Macromol., 2016;0(0):.
    Species: Mouse
    Sample Types: Serum
  88. Anti-inflammatory effect of cannabinoid agonist WIN55, 212 on mouse experimental colitis is related to inhibition of p38MAPK
    World J. Gastroenterol., 2016;22(43):9515-9524.
    Species: Mouse
    Sample Types: Plasma
  89. The cannabinoid receptor CB1 contributes to the development of ectopic lesions in a mouse model of endometriosis
    Authors: Paola Panina-Bor
    Hum. Reprod., 2016;0(0):.
    Species: Mouse
    Sample Types: Peritoneal Lavage Fluid
  90. Inhibition of Interleukin-6 Receptor in a Murine Model of Myocardial Ischemia-Reperfusion
    PLoS ONE, 2016;11(12):e0167195.
    Species: Mouse
    Sample Types: Plasma
  91. Toll-Like Receptor 4 Signaling Pathway Mediates Inhalant Organic Dust-Induced Bone Loss
    PLoS ONE, 2016;11(8):e0158735.
    Species: Mouse
    Sample Types: BALF
  92. Pivotal Role of Carbohydrate Sulfotransferase 15 in Fibrosis and Mucosal Healing in Mouse Colitis
    PLoS ONE, 2016;11(7):e0158967.
  93. Sharpin Controls Osteogenic Differentiation of Mesenchymal Bone Marrow Cells.
    Authors: Jeschke A, Catala-Lehnen P, Sieber S, Bickert T, Schweizer M, Koehne T, Wintges K, Marshall R, Mautner A, Duchstein L, Otto B, Horst A, Amling M, Kreienkamp H, Schinke T
    J Immunol, 2015;195(8):3675-84.
    Species: Mouse
    Sample Types: Serum
  94. Thrombomodulin alleviates murine GVHD in association with an increase in the proportion of regulatory T cells in the spleen.
    Authors: Ikezoe T, Yang J, Nishioka C, Yokoyama A
    Bone Marrow Transplant, 2015;50(1):113-20.
    Species: Mouse
    Sample Types: Plasma
  95. Pharmacologic Inhibition of JAK1/JAK2 Signaling Reduces Experimental Murine Acute GVHD While Preserving GVT Effects.
    Authors: Carniti C, Gimondi S, Vendramin A, Recordati C, Confalonieri D, Bermema A, Corradini P, Mariotti J
    Clin Cancer Res, 2015;21(16):3740-9.
    Species: Mouse
    Sample Types: Serum
  96. MicroRNA-22 impairs anti-tumor ability of dendritic cells by targeting p38.
    Authors: Liang X, Liu Y, Mei S, Zhang M, Xin J, Zhang Y, Yang R
    PLoS ONE, 2015;10(3):e0121510.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  97. Conditioned media from adipose stromal cells limit lipopolysaccharide-induced lung injury, endothelial hyperpermeability and apoptosis.
    Authors: Lu H, Poirier C, Cook T, Traktuev D, Merfeld-Clauss S, Lease B, Petrache I, March K, Bogatcheva N
    J Transl Med, 2015;13(0):67.
    Species: Mouse
    Sample Types: BALF
  98. Microglial Kv1.3 Channels and P2Y12 Receptors Differentially Regulate Cytokine and Chemokine Release from Brain Slices of Young Adult and Aged Mice.
    Authors: Charolidi N, Schilling T, Eder C
    PLoS ONE, 2015;10(5):e0128463.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  99. Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension.
    Authors: Goodall L, Ovecka M, Rycroft D, Friel S, Sanderson A, Mistry P, Davies M, Stoop A
    PLoS ONE, 2015;10(9):e0137065.
  100. Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-kappaB and AP-1 Activation.
    Authors: Fan B, Dun S, Gu J, Guo Y, Ikuyama S
    PLoS ONE, 2015;10(9):e0137837.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  101. Sevoflurane inhibits nuclear factor-kappaB activation in lipopolysaccharide-induced acute inflammatory lung injury via toll-like receptor 4 signaling.
    Authors: Sun X, Li X, Wang X, Tan W, Wang J
    PLoS ONE, 2015;10(4):e0122752.
    Species: Mouse
    Sample Types: BALF
  102. Critical role for IL-18 in spontaneous lung inflammation caused by autophagy deficiency.
    Authors: Abdel Fattah E, Bhattacharya A, Herron A, Safdar Z, Eissa N
    J Immunol, 2015;194(11):5407-16.
    Species: Mouse
    Sample Types: BALF
  103. Chronic morphine-induced microRNA-124 promotes microglial immunosuppression by modulating P65 and TRAF6.
    Authors: Qiu S, Feng Y, LeSage G, Zhang Y, Stuart C, He L, Li Y, Caudle Y, Peng Y, Yin D
    J Immunol, 2015;194(3):1021-30.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  104. Innate sensing of microbial products promotes wound-induced skin cancer.
    Authors: Hoste E, Arwert E, Lal R, South A, Salas-Alanis J, Murrell D, Donati G, Watt F
    Nat Commun, 2015;6(0):5932.
    Species: Mouse
    Sample Types: Serum
  105. Activation of p38 Mitogen-Activated Protein Kinase in Gaucher's Disease.
    Authors: Kitatani K, Wada M, Perry D, Usui T, Sun Y, Obeid L, Yaegashi N, Grabowski G, Hannun Y
    PLoS ONE, 2015;10(8):e0136633.
    Species: Mouse
    Sample Types: Serum
  106. Loss of the polarity protein PAR3 activates STAT3 signaling via an atypical protein kinase C (aPKC)/NF-kappaB/interleukin-6 (IL-6) axis in mouse mammary cells.
    Authors: Guyer R, Macara I
    J Biol Chem, 2015;290(13):8457-68.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  107. Systemic siRNA Nanoparticle-Based Drugs Combined with Radiofrequency Ablation for Cancer Therapy.
    Authors: Ahmed M, Kumar G, Navarro G, Wang Y, Gourevitch S, Moussa M, Rozenblum N, Levchenko T, Galun E, Torchilin V, Goldberg S
    PLoS ONE, 2015;10(7):e0128910.
    Species: Mouse
    Sample Types: Tissue Homogenates
  108. Kruppel-like factor 9 deficiency in uterine endometrial cells promotes ectopic lesion establishment associated with activated notch and hedgehog signaling in a mouse model of endometriosis.
    Authors: Heard M, Simmons C, Simmen F, Simmen R
    Endocrinology, 2014;155(4):1532-46.
    Species: Mouse
    Sample Types: Serum
  109. Activating transcription factor 4 links metabolic stress to interleukin-6 expression in macrophages.
    Authors: Iwasaki Y, Suganami T, Hachiya R, Shirakawa I, Kim-Saijo M, Tanaka M, Hamaguchi M, Takai-Igarashi T, Nakai M, Miyamoto Y, Ogawa Y
    Diabetes, 2014;63(1):152-61.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  110. Role of TLR5 and flagella in bacillus intraocular infection.
    Authors: Parkunan, Salai Ma, Astley, Roger, Callegan, Michelle
    PLoS ONE, 2014;9(6):e100543.
    Species: Mouse
    Sample Types: Tissue Homogenates
  111. CCR1 inhibition ameliorates the progression of lupus nephritis in NZB/W mice.
    Authors: Bignon A, Gaudin F, Hemon P, Tharinger H, Mayol K, Walzer T, Loetscher P, Peuchmaur M, Berrebi D, Balabanian K
    J Immunol, 2014;192(3):886-96.
    Species: Mouse
    Sample Types: Serum
  112. Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts.
    Authors: Le Goff B, Singbrant S, Tonkin B, Martin T, Romas E, Sims N, Walsh N
    Cytokine, 2014;68(2):101-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  113. NF-kappaB signaling modulates radiationinduced microglial activation.
    Authors: Xue J, Dong J, Huang G, Qu X, Wu G, Dong X
    Oncol Rep, 2014;31(6):2555-60.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  114. Effect of ADAMTS-13 on cerebrovascular microthrombosis and neuronal injury after experimental subarachnoid hemorrhage.
    Authors: Muroi C, Fujioka M, Mishima K, Irie K, Fujimura Y, Nakano T, Fandino J, Keller E, Iwasaki K, Fujiwara M
    J Thromb Haemost, 2014;12(4):505-14.
    Species: Mouse
    Sample Types: Whole Blood
  115. Diisopropylamine dichloroacetate, a novel pyruvate dehydrogenase kinase 4 inhibitor, as a potential therapeutic agent for metabolic disorders and multiorgan failure in severe influenza.
    Authors: Yamane, Kazuhiko, Indalao, Irene L, Chida, Junji, Yamamoto, Yoshikaz, Hanawa, Masaaki, Kido, Hiroshi
    PLoS ONE, 2014;9(5):e98032.
    Species: Mouse
    Sample Types: Tissue Homogenates
  116. Microglia trigger astrocyte-mediated neuroprotection via purinergic gliotransmission.
    Authors: Shinozaki Y, Nomura M, Iwatsuki K, Moriyama Y, Gachet C, Koizumi S
    Sci Rep, 2014;4(0):4329.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  117. Role of ferulic acid in the amelioration of ionizing radiation induced inflammation: a murine model.
    Authors: Das U, Manna K, Sinha M, Datta S, Das D, Chakraborty A, Ghosh M, Saha K, Dey S
    PLoS ONE, 2014;9(5):e97599.
    Species: Mouse
    Sample Types: Serum
  118. Ad5/48 hexon oncolytic virus expressing sTGFbetaRIIFc produces reduced hepatic and systemic toxicities and inhibits prostate cancer bone metastases.
    Authors: Xu W, Zhang Z, Yang Y, Hu Z, Wang C, Morgan M, Wu Y, Hutten R, Xiao X, Stock S, Guise T, Prabhakar B, Brendler C, Seth P
    Mol Ther, 2014;22(8):1504-17.
    Species: Mouse
    Sample Types: Serum
  119. Rho-kinase activation in leukocytes plays a pivotal role in myocardial ischemia/reperfusion injury.
    Authors: Kitano K, Usui S, Ootsuji H, Takashima S, Kobayashi D, Murai H, Furusho H, Nomura A, Kaneko S, Takamura M
    PLoS ONE, 2014;9(3):e92242.
  120. Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-kappaB activation through TBK1.
    Authors: Abe T, Barber G
    J Virol, 2014;88(10):5328-41.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  121. Running exercise alleviates trabecular bone loss and osteopenia in hemizygous beta-globin knockout thalassemic mice.
    Authors: Thongchote K, Svasti S, Teerapornpuntakit J, Krishnamra N, Charoenphandhu N
    Am J Physiol Endocrinol Metab, 2014;306(12):E1406-17.
    Species: Mouse
    Sample Types: Serum
  122. Akt2 deficiency protects from acute lung injury via alternative macrophage activation and miR-146a induction in mice.
    Authors: Vergadi, Eleni, Vaporidi, Katerina, Theodorakis, Emmanuel, Doxaki, Christin, Lagoudaki, Eleni, Ieronymaki, Elefther, Alexaki, Vassilia, Helms, Mike, Kondili, Eumorfia, Soennichsen, Birte, Stathopoulos, Efstathi, Margioris, Andrew N, Georgopoulos, Dimitrio, Tsatsanis, Christos
    J Immunol, 2014;192(1):394-406.
    Species: Mouse
    Sample Types: BALF
  123. Fatty acids increase hepatitis B virus X protein stabilization and HBx-induced inflammatory gene expression.
    Authors: Cho H, Kim S, Yoo S, Choi Y, Cheong J
    FEBS J, 2014;281(9):2228-39.
    Species: Mouse
    Sample Types: Tissue Homogenates
  124. The effects of protein malnutrition on the TNF-RI and NF-kappaB expression via the TNF-alpha signaling pathway.
    Authors: de Oliveira D, Hastreiter A, Mello A, de Oliveira Beltran J, Oliveira Santos E, Borelli P, Fock R
    Cytokine, 2014;69(2):218-25.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  125. Peripheral surgical wounding and age-dependent neuroinflammation in mice.
    Authors: Xu Z, Dong Y, Wang H, Culley D, Marcantonio E, Crosby G, Tanzi R, Zhang Y, Xie Z
    PLoS ONE, 2014;9(5):e96752.
    Species: Mouse
    Sample Types: Tissue Homogenates
  126. TBK1 mediates critical effects of measles virus nucleocapsid protein (MVNP) on pagetic osteoclast formation.
    Authors: Sun Q, Sammut B, Wang F, Kurihara N, Windle J, Roodman G, Galson D
    J Bone Miner Res, 2014;29(1):90-102.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  127. Elevated levels of mast cells are involved in pruritus associated with polycythemia vera in JAK2V617F transgenic mice.
    Authors: Jin X, Zhao W, Kirabo A, Park S, Ho W, Sayeski P, Zhao Z
    J Immunol, 2014;193(2):477-84.
    Species: Mouse
    Sample Types: Tissue Homogenates
  128. Celecoxib sensitizes Staphylococcus aureus to antibiotics in macrophages by modulating SIRT1.
    Authors: Annamanedi M, Kalle A
    PLoS ONE, 2014;9(6):e99285.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  129. Knockdown of TrkA in cumulus oocyte complexes (COCs) inhibits EGF-induced cumulus expansion by down-regulation of IL-6.
    Authors: Wang Y, Liang N, Yao G, Tian H, Zhai Y, Yin Y, Sun F
    Mol Cell Endocrinol, 2014;382(2):804-13.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  130. Fibrates ameliorate the course of bacterial sepsis by promoting neutrophil recruitment via CXCR2.
    Authors: Tancevski I, Nairz M, Duwensee K, Auer K, Schroll A, Heim C, Feistritzer C, Hoefer J, Gerner R, Moschen A, Heller I, Pallweber P, Li X, Theurl M, Demetz E, Wolf A, Wolf D, Eller P, Ritsch A, Weiss G
    EMBO Mol Med, 2014;6(6):810-20.
    Species: Mouse
    Sample Types: Serum
  131. Acute lung injury and acute kidney injury are established by four hours in experimental sepsis and are improved with pre, but not post, sepsis administration of TNF-alpha antibodies.
    Authors: Bhargava R, Altmann C, Andres-Hernando A, Webb R, Okamura K, Yang Y, Falk S, Schmidt E, Faubel S
    PLoS ONE, 2013;8(11):e79037.
    Species: Mouse
    Sample Types: Urine
  132. Hypoxia antagonizes glucose deprivation on interleukin 6 expression in an Akt dependent, but HIF-1/2alpha independent manner.
    Authors: Choi S, Shin I, Je K, Min E, Kim E, Kim H, Choe S, Kim D, Lee D
    PLoS ONE, 2013;8(3):e58662.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  133. mTORC1 and mTORC2 play different roles in the functional survival of transplanted adipose-derived stromal cells in hind limb ischemic mice via regulating inflammation in vivo.
    Authors: Fan W, Cheng K, Qin X, Narsinh K, Wang S, Hu S, Wang Y, Chen Y, Wu J, Xiong L, Cao F
    Stem Cells, 2013;31(1):203-14.
    Species: Mouse
    Sample Types: Tissue Homogenates
  134. Sirt2 suppresses inflammatory responses in collagen-induced arthritis.
    Authors: Lin J, Sun B, Jiang C, Hong H, Zheng Y
    Biochem Biophys Res Commun, 2013;441(4):897-903.
    Species: Mouse
    Sample Types: Serum
  135. Expression of HIV transgene aggravates kidney injury in diabetic mice.
    Authors: Mallipattu S, Liu R, Zhong Y, Chen E, D'Agati V, Kaufman L, Ma'ayan A, Klotman P, Chuang P, He J
    Kidney Int, 2013;83(4):626-34.
    Species: Mouse
    Sample Types: Serum
  136. Inflammation induced by MMP-9 enhances tumor regression of experimental breast cancer.
    Authors: Leifler K, Svensson S, Abrahamsson A, Bendrik C, Robertson J, Gauldie J, Olsson A, Dabrosin C
    J Immunol, 2013;190(8):4420-30.
    Species: Mouse
    Sample Types: Tissue Homogenates
  137. Inhibition of geranylgeranyltransferase attenuates neutrophil accumulation and tissue injury in severe acute pancreatitis.
    Authors: Merza M, Wetterholm E, Zhang S, Regner S, Thorlacius H
    J Leukoc Biol, 2013;94(3):493-502.
    Species: Mouse
    Sample Types: Plasma
  138. Antisense oligonucleotide treatment enhances the recovery of acute lung injury through IL-10-secreting M2-like macrophage-induced expansion of CD4+ regulatory T cells.
    Authors: Guo Z, Wen Z, Qin A, Zhou Y, Liao Z, Liu Z, Liang Y, Ren T, Xu L
    J Immunol, 2013;190(8):4337-48.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  139. Enhanced immunogenicity of a tricomponent mannan tetanus toxoid conjugate vaccine targeted to dendritic cells via Dectin-1 by incorporating beta-glucan.
    Authors: Lipinski T, Fitieh A, St Pierre J, Ostergaard H, Bundle D, Touret N
    J Immunol, 2013;190(8):4116-28.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  140. MEKK2 kinase association with 14-3-3 protein regulates activation of c-Jun N-terminal kinase.
    Authors: Matitau A, Gabor T, Gill R, Scheid M
    J Biol Chem, 2013;288(39):28293-302.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  141. Absence of T and B lymphocytes modulates dystrophic features in dysferlin deficient animal model.
    Authors: Farini A, Sitzia C, Navarro C, D'Antona G, Belicchi M, Parolini D, Del Fraro G, Razini P, Bottinelli R, Meregalli M, Torrente Y
    Exp. Cell Res., 2012;318(10):1160-74.
    Species: Mouse
    Sample Types: Tissue Homogenates
  142. Impairment of bilirubin clearance and intestinal interleukin-6 expression in bile duct-ligated vitamin D receptor null mice.
    Authors: Ishizawa M, Ogura M, Kato S, Makishima M
    PLoS ONE, 2012;7(12):e51664.
    Species: Mouse
    Sample Types: Plasma
  143. Human mesenchymal stem/stromal cells cultured as spheroids are self-activated to produce prostaglandin E2 that directs stimulated macrophages into an anti-inflammatory phenotype.
    Authors: Ylostalo J, Bartosh T, Coble K, Prockop D
    Stem Cells, 2012;30(10):2283-96.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  144. Inhalative vs. systemic IL-10 administration: differences in the systemic inflammatory response and end-organ inflammation following hemorrhagic shock.
    Authors: Pfeifer R, Lichte P, Schreiber H, Sellei R, Schmidt J, Dombroski D, Pape H, Kobbe P
    Cytokine, 2012;60(1):266-70.
    Species: Mouse
    Sample Types: Serum
  145. TBK1-associated protein in endolysosomes (TAPE)/CC2D1A is a key regulator linking RIG-I-like receptors to antiviral immunity.
    Authors: Chen K, Chang C, Huang C, Lin C, Lin W, Lo Y, Yang C, Hsing E, Chen L, Shih S, Shiau A, Lei H, Tan T, Ling P
    J Biol Chem, 2012;287(38):32216-21.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  146. Toll-like receptor-mediated inhibition of Gas6 and ProS expression facilitates inflammatory cytokine production in mouse macrophages.
    Authors: Deng T, Zhang Y, Chen Q, Yan K, Han D
    Immunology, 2012;135(1):40-50.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  147. Tangeretin stimulates glucose uptake via regulation of AMPK signaling pathways in C2C12 myotubes and improves glucose tolerance in high-fat diet-induced obese mice.
    Mol. Cell. Endocrinol., 2012;358(1):127-34.
    Species: Mouse
    Sample Types: Serum
  148. Dual functions of prostaglandin D2 in murine contact hypersensitivity via DP and CRTH2.
    Authors: Yamamoto Y, Otani S, Hirai H, Nagata K, Aritake K, Urade Y, Narumiya S, Yokozeki H, Nakamura M, Satoh T
    Am. J. Pathol., 2012;179(1):302-14.
    Species: Mouse
    Sample Types: Tissue Homogenates
  149. Activated protein C inhibits pancreatic islet inflammation, stimulates T regulatory cells, and prevents diabetes in non-obese diabetic (NOD) mice.
    Authors: Xue M, Dervish S, Harrison LC, Fulcher G, Jackson CJ
    J. Biol. Chem., 2012;287(20):16356-64.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  150. Treatment of diabetic mice with undenatured whey protein accelerates the wound healing process by enhancing the expression of MIP-1alpha, MIP-2, KC, CX3CL1 and TGF-beta in wounded tissue.
    BMC Immunol., 2012;13(0):32.
    Species: Mouse
    Sample Types: Tissue Homogenates
  151. Disruption of the chemokine-like receptor-1 (CMKLR1) gene is associated with reduced adiposity and glucose intolerance.
    Authors: Ernst MC, Haidl ID, Zúñiga LA, Dranse HJ, Rourke JL, Zabel BA, Butcher EC, Sinal CJ
    Endocrinology, 2012;153(2):672-82.
    Species: Mouse
    Sample Types: Serum
  152. Cutting edge: Divergent cell-specific functions of MyD88 for inflammatory responses and organ injury in septic peritonitis.
    Authors: Gais P, Reim D, Jusek G, Rossmann-Bloeck T, Weighardt H, Pfeffer K, Altmayr F, Janssen KP, Holzmann B
    J. Immunol., 2012;188(12):5833-7.
    Species: Mouse
    Sample Types: Plasma
  153. The Receptor Slamf1 on the Surface of Myeloid Lineage Cells Controls Susceptibility to Infection by Trypanosoma cruzi.
    Authors: Calderon J, Maganto-Garcia E, Punzon C, Carrion J, Terhorst C, Fresno M
    PLoS Pathog., 2012;8(7):e1002799.
    Species: Mouse
    Sample Types: Serum
  154. Stress augments insulin resistance and prothrombotic state: role of visceral adipose-derived monocyte chemoattractant protein-1.
    Authors: Uchida Y, Takeshita K, Yamamoto K, Kikuchi R, Nakayama T, Nomura M, Cheng XW, Egashira K, Matsushita T, Nakamura H, Murohara T
    Diabetes, 2012;61(6):1552-61.
    Species: Mouse
    Sample Types: Serum
  155. Netrin-1 protects against L-Arginine-induced acute pancreatitis in mice.
    Authors: Chen J, Cai Q, Shen P, Yan R, Wang C, Yang D, Fu H, Chen X
    PLoS ONE, 2012;7(9):e46201.
    Species: Mouse
    Sample Types: Plasma
  156. Fetuin-A acts as an endogenous ligand of TLR4 to promote lipid-induced insulin resistance.
    Nat Med, 2012;18(0):1279.
    Species: Mouse
    Sample Types: Serum
  157. Class I/II hybrid inhibitory oligodeoxynucleotide exerts Th1 and Th2 double immunosuppression.
    Authors: Ito Y, Shigemori S, Sato T, Shimazu T, Hatano K, Otani H, Kitazawa H, Shimosato T
    FEBS Open Bio, 2012;3(0):41-5.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  158. The axonal guidance receptor neogenin promotes acute inflammation.
    Authors: Konig K, Gatidou D, Granja T, Meier J, Rosenberger P, Mirakaj V
    PLoS ONE, 2012;7(3):e32145.
    Species: Mouse
    Sample Types: Peritoneal Lavage
  159. Endothelial cell peroxisome proliferator-activated receptor gamma reduces endotoxemic pulmonary inflammation and injury.
    Authors: Reddy A, Lakshmi S, Kleinhenz J, Sutliff R, Hart C, Reddy R
    J Immunol, 2012;189(11):5411-20.
    Species: Mouse
    Sample Types: BALF
  160. XOMA 052, a potent, high-affinity monoclonal antibody for the treatment of IL-1beta-mediated diseases.
    Authors: Owyang AM, Issafras H, Corbin J, Ahluwalia K, Larsen P, Pongo E, Handa M, Horwitz AH, Roell MK, Haak-Frendscho M, Masat L
    MAbs, 2011;3(1):49-60.
    Species: Mouse
    Sample Types: Serum
  161. Deletion of tristetraprolin caused spontaneous reactive granulopoiesis by a non-cell-autonomous mechanism without disturbing long-term hematopoietic stem cell quiescence.
    Authors: Kaplan IM, Morisot S, Heiser D, Cheng WC, Kim MJ, Civin CI
    J. Immunol., 2011;186(5):2826-34.
    Species: Mouse
    Sample Types: Plasma
  162. IL-33-activated dendritic cells are critical for allergic airway inflammation.
    Authors: Besnard AG, Togbe D, Guillou N, Erard F, Quesniaux V, Ryffel B
    Eur. J. Immunol., 2011;41(6):1675-86.
    Species: Mouse
    Sample Types: BALF
  163. Repulsive guidance molecule-A (RGM-A) inhibits leukocyte migration and mitigates inflammation.
    Authors: Mirakaj V, Brown S, Laucher S, Steinl C, Klein G, Kohler D, Skutella T, Meisel C, Brommer B, Rosenberger P, Schwab JM
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(16):6555-60.
    Species: Mouse
    Sample Types: Peritoneal Lavage
  164. Improved host defense against septic peritonitis in mice lacking MyD88 and TRIF is linked to a normal interferon response.
    Authors: Reim D, Rossmann-Bloeck T, Jusek G, Prazeres da Costa O, Holzmann B
    J. Leukoc. Biol., 2011;90(3):613-20.
    Species: Mouse
    Sample Types: Plasma
  165. TLR4 through IFN-beta promotes low molecular mass hyaluronan-induced neutrophil apoptosis.
    Authors: Leu SW, Shi L, Xu C, Zhao Y, Liu B, Li Y, Shiedlin A, Xiang C, Shen H, Quinn DA, Hales CA, Zhao H
    J. Immunol., 2011;186(1):556-62.
    Species: Mouse
    Sample Types: BALF
  166. The interaction between IL-18 and IL-18 receptor limits the magnitude of protective immunity and enhances pathogenic responses following infection with intracellular bacteria.
    Authors: Ghose P, Ali AQ, Fang R, Forbes D, Ballard B, Ismail N
    J. Immunol., 2011;187(3):1333-46.
    Species: Mouse
    Sample Types: Serum
  167. Histone Deacetylase Inhibitor LAQ824 Augments Inflammatory Responses in Macrophages through Transcriptional Regulation of IL-10.
    Authors: Wang H, Cheng F
    J. Immunol., 2011;186(0):3986.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  168. Aryl hydrocarbon receptor deficiency in T cells suppresses the development of collagen-induced arthritis.
    Authors: Nakahama T, Kimura A, Nguyen NT, Chinen I, Hanieh H, Nohara K, Fujii-Kuriyama Y, Kishimoto T
    Proc. Natl. Acad. Sci. U.S.A., 2011;108(34):14222-7.
    Species: Mouse
    Sample Types: Serum
  169. Sterol regulatory element-binding protein 2 (SREBP2) activation after excess triglyceride storage induces chemerin in hypertrophic adipocytes.
    Authors: Bauer S, Wanninger J, Schmidhofer S, Weigert J, Neumeier M, Dorn C, Hellerbrand C, Zimara N, Schaffler A, Aslanidis C, Buechler C
    Endocrinology, 2011;152(1):26-35.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  170. Crawling Phagocytes Recruited in the Brain Vasculature after Pertussis Toxin Exposure through IL6, ICAM1 and ITGalphaM.
    Authors: Richard JF, Roy M, Audoy-Remus J, Tremblay P, Vallieres L
    Brain Pathol., 2011;21(0):661.
    Species: Mouse
    Sample Types: Serum
  171. Mechanisms inducing low bone density in duchenne muscular dystrophy in mice and humans.
    Authors: Rufo A, Del Fattore A, Capulli M, Carvello F, De Pasquale L, Ferrari S, Pierroz D, Morandi L, De Simone M, Rucci N, Bertini E, Bianchi ML, De Benedetti F, Teti A
    J. Bone Miner. Res., 2011;26(8):1891-903.
    Species: Mouse
    Sample Types: Serum
  172. Tumors Suppress In Situ Proliferation of Cytotoxic T Cells by Promoting Differentiation of Gr-1+ Conventional Dendritic Cells through IL-6.
    Authors: Diao J, Zhao J, Winter E
    J. Immunol., 2011;186(9):5058-67.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  173. Serotonin activates dendritic cell function in the context of gut inflammation.
    Authors: Li N, Ghia JE, Wang H, McClemens J, Cote F, Suehiro Y, Mallet J, Khan WI
    Am. J. Pathol., 2011;178(2):662-71.
    Species: Mouse
    Sample Types: Tissue Homogenates
  174. Differential host determinants contribute to the pathogenesis of 2009 pandemic H1N1 and human H5N1 influenza A viruses in experimental mouse models.
    Authors: Otte A, Sauter M, Alleva L, Baumgarte S, Klingel K, Gabriel G
    Am. J. Pathol., 2011;179(1):230-9.
    Species: Mouse
    Sample Types: Serum
  175. Action at a distance: systemically administered adult stem/progenitor cells (MSCs) reduce inflammatory damage to the cornea without engraftment and primarily by secretion of TNF-alpha stimulated gene/protein 6.
    Authors: Roddy GW, Oh JY, Lee RH, Bartosh TJ, Ylostalo J, Coble K, Rosa RH, Prockop DJ
    Stem Cells, 2011;29(10):1572-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  176. The adaptor molecule CARD9 is essential for tuberculosis control.
    Authors: Dorhoi A, Desel C, Yeremeev V, Pradl L, Brinkmann V, Mollenkopf HJ, Hanke K, Gross O, Ruland J, Kaufmann SH
    J. Exp. Med., 2011;207(4):777-92.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  177. Inhibition of bone morphogenetic protein signaling attenuates anemia associated with inflammation.
    Authors: Steinbicker AU, Sachidanandan C, Vonner AJ
    Blood, 2011;117(18):4915-23.
    Species: Mouse
    Sample Types: Serum
  178. Loss of ability to self-heal malaria upon taurine transporter deletion.
    Authors: Delic D, Warskulat U, Borsch E, Al-Qahtani S, Al-Quraishi S, Haussinger D, Wunderlich F
    Infect. Immun., 2010;78(4):1642-9.
    Species: Mouse
    Sample Types: Serum
  179. TLR4 activation is required for IL-17-induced multiple tissue inflammation and wasting in mice.
    Authors: Tang H, Pang S, Wang M
    J. Immunol., 2010;185(4):2563-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  180. Enhanced production of IL-17A during zymosan-induced peritonitis in obese mice.
    Authors: Pini M, Fantuzzi G
    J. Leukoc. Biol., 2010;87(1):51-8.
    Species: Mouse
    Sample Types: Peritoneal Lavage
  181. Myeloid PTEN promotes inflammation but impairs bactericidal activities during murine pneumococcal pneumonia.
    Authors: Schabbauer G, Matt U, Gunzl P, Warszawska J, Furtner T, Hainzl E, Elbau I, Mesteri I, Doninger B, Binder BR, Knapp S
    J. Immunol., 2010;185(1):468-76.
    Species: Mouse
    Sample Types: BALF
  182. Cell adhesion molecules regulate fibrotic process via Th1/Th2/Th17 cell balance in a bleomycin-induced scleroderma model.
    Authors: Yoshizaki A, Yanaba K, Iwata Y
    J. Immunol., 2010;185(4):2502-15.
    Species: Mouse
    Sample Types: Serum
  183. Varying susceptibility of pulmonary cytokine production to lipopolysaccharide in mice.
    Authors: Alm AS, Li K, Yang D, Andersson R, Lu Y, Wang X
    Cytokine, 2010;49(3):256-63.
    Species: Mouse
    Sample Types: BALF
  184. Ability of IDO to attenuate liver injury in alpha-galactosylceramide-induced hepatitis model.
    Authors: Ito H, Hoshi M, Ohtaki H, Taguchi A, Ando K, Ishikawa T, Osawa Y, Hara A, Moriwaki H, Saito K, Seishima M
    J. Immunol., 2010;185(8):4554-60.
    Species: Mouse
    Sample Types: Serum
  185. Essential roles of IL-6 trans-signaling in colonic epithelial cells, induced by the IL-6/soluble-IL-6 receptor derived from lamina propria macrophages, on the development of colitis-associated premalignant cancer in a murine model.
    Authors: Matsumoto S, Hara T, Mitsuyama K, Yamamoto M, Tsuruta O, Sata M, Scheller J, Rose-John S, Kado S, Takada T
    J. Immunol., 2010;184(3):1543-51.
    Species: Mouse
    Sample Types: Tissue Homogenates
  186. Early protection from burn-induced acute lung injury by deletion of preprotachykinin-A gene.
    Authors: Sio SW, Moochhala S, Lu J
    Am. J. Respir. Crit. Care Med., 2010;181(1):36-46.
    Species: Mouse
    Sample Types: Tissue Homogenates
  187. Systemic inflammation sensitizes the neonatal brain to excitotoxicity through a pro-/anti-inflammatory imbalance: key role of TNFalpha pathway and protection by etanercept.
    Authors: Aden U, Favrais G, Plaisant F, Winerdal M, Felderhoff-Mueser U, Lampa J, Lelievre V, Gressens P
    Brain Behav. Immun., 2010;24(5):747-58.
    Species: Mouse
    Sample Types: Tissue Homogenates
  188. Activation of the NLRP3 inflammasome by islet amyloid polypeptide provides a mechanism for enhanced IL-1beta in type 2 diabetes.
    Authors: Masters SL, Dunne A, Subramanian SL, Hull RL, Tannahill GM, Sharp FA, Becker C, Franchi L, Yoshihara E, Chen Z, Mullooly N, Mielke LA, Harris J, Coll RC, Mills KH, Mok KH, Newsholme P, Nunez G, Yodoi J, Kahn SE, Lavelle EC, O'Neill LA
    Nat. Immunol., 2010;11(10):897-904.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  189. Neutralization of osteopontin inhibits obesity-induced inflammation and insulin resistance.
    Authors: Kiefer FW, Zeyda M, Gollinger K, Pfau B, Neuhofer A, Weichhart T, Saemann MD, Geyeregger R, Schlederer M, Kenner L, Stulnig TM
    Diabetes, 2010;59(4):935-46.
    Species: Mouse
    Sample Types: Plasma
  190. TLR4 is a negative regulator in noninfectious lung inflammation.
    Authors: Zhao H, Leu SW, Shi L, Dedaj R, Zhao G, Garg HG, Shen L, Lien E, Fitzgerald KA, Shiedlin A, Shen H, Quinn DA, Hales CA
    J. Immunol., 2010;184(9):5308-14.
    Species: Mouse
    Sample Types: BALF
  191. Growth arrest-specific protein 6 deficiency impairs liver tissue repair after acute toxic hepatitis in mice.
    Authors: Lafdil F, Chobert MN, Deveaux V, Zafrani ES, Mavier P, Nakano T, Laperche Y, Brouillet A
    J. Hepatol., 2009;51(1):55-66.
    Species: Mouse
    Sample Types: Tissue Homogenates
  192. Anti-inflammatory effects of ethyl acetate fraction from Melilotus suaveolens Ledeb on LPS-stimulated RAW 264.7 cells.
    Authors: Tao JY, Zheng GH, Zhao L, Wu JG, Zhang XY, Zhang SL, Huang ZJ, Xiong FL, Li CM
    J Ethnopharmacol, 2009;123(1):97-105.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  193. Anchoring fusion thrombomodulin to the endothelial lumen protects against injury-induced lung thrombosis and inflammation.
    Authors: Ding BS, Hong N, Christofidou-Solomidou M, Gottstein C, Albelda SM, Cines DB, Fisher AB, Muzykantov VR
    Am. J. Respir. Crit. Care Med., 2009;180(3):247-56.
    Species: Mouse
    Sample Types: BALF
  194. The Down syndrome critical region gene 1 short variant promoters direct vascular bed-specific gene expression during inflammation in mice.
    Authors: Minami T, Yano K, Miura M, Kobayashi M, Suehiro J, Reid PC, Hamakubo T, Ryeom S, Aird WC, Kodama T
    J. Clin. Invest., 2009;119(8):2257-70.
    Species: Mouse
    Sample Types: Plasma
  195. Bbeta(15-42) protects against acid-induced acute lung injury and secondary pseudomonas pneumonia in vivo.
    Authors: Matt U, Warszawska JM, Bauer M, Dietl W, Mesteri I, Doninger B, Haslinger I, Schabbauer G, Perkmann T, Binder CJ, Reingruber S, Petzelbauer P, Knapp S
    Am. J. Respir. Crit. Care Med., 2009;180(12):1208-17.
    Species: Mouse
    Sample Types: BALF
  196. Combined inhibition of janus kinase 1/2 for the treatment of JAK2V617F-driven neoplasms: selective effects on mutant cells and improvements in measures of disease severity.
    Authors: Liu PC, Caulder E, Li J, Waeltz P, Margulis A, Wynn R, Becker-Pasha M, Li Y, Crowgey E, Hollis G, Haley P, Sparks RB, Combs AP, Rodgers JD, Burn TC, Vaddi K, Fridman JS
    Clin. Cancer Res., 2009;15(22):6891-900.
    Species: Mouse
    Sample Types: Plasma
  197. Loss-of-function mutation in myostatin reduces tumor necrosis factor alpha production and protects liver against obesity-induced insulin resistance.
    Authors: Wilkes JJ, Lloyd DJ, Gekakis N
    Diabetes, 2009;58(5):1133-43.
    Species: Mouse
    Sample Types: Plasma
  198. Unc93B1 biases Toll-like receptor responses to nucleic acid in dendritic cells toward DNA- but against RNA-sensing.
    Authors: Fukui R, Saitoh S, Matsumoto F, Kozuka-Hata H, Oyama M, Tabeta K, Beutler B, Miyake K
    J. Exp. Med., 2009;206(6):1339-50.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  199. Inhibition of the chemokine (C-C motif) ligand 2/chemokine (C-C motif) receptor 2 pathway attenuates hyperglycaemia and inflammation in a mouse model of hepatic steatosis and lipoatrophy.
    Authors: Yang SJ, IglayReger HB, Kadouh HC, Bodary PF
    Diabetologia, 2009;52(0):972-81.
    Species: Mouse
    Sample Types: Plasma
  200. Inhibition of interleukin-33 signaling attenuates the severity of experimental arthritis.
    Authors: Palmer G, Talabot-Ayer D, Lamacchia C, Toy D, Seemayer CA, Viatte S, Finckh A, Smith DE, Gabay C
    Arthritis Rheum., 2009;60(3):738-49.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  201. An activating and inhibitory signal from an inhibitory receptor LMIR3/CLM-1: LMIR3 augments lipopolysaccharide response through association with FcRgamma in mast cells.
    Authors: Izawa K, Kitaura J, Yamanishi Y, Matsuoka T, Kaitani A, Sugiuchi M, Takahashi M, Maehara A, Enomoto Y, Oki T, Takai T, Kitamura T
    J. Immunol., 2009;183(2):925-36.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  202. Uropathogenic Escherichia coli-induced inflammation alters mouse urinary bladder contraction via an interleukin-6-activated inducible nitric oxide synthase-related pathway.
    Authors: Weng TI, Wu HY, Lin PY, Liu SH
    Infect. Immun., 2009;77(8):3312-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  203. TNFalpha inhibits apoptotic cell clearance in the lung, exacerbating acute inflammation.
    Authors: Borges VM, Vandivier RW, McPhillips KA, Kench JA, Morimoto K, Groshong SD, Richens TR, Graham BB, Muldrow AM, Van Heule L, Henson PM, Janssen WJ
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(4):L586-95.
    Species: Mouse
    Sample Types: BALF
  204. Effects of a leukotriene B4 receptor antagonist on bleomycin-induced pulmonary fibrosis.
    Authors: Izumo T, Kondo M, Nagai A
    Eur. Respir. J., 2009;34(6):1444-51.
    Species: Mouse
    Sample Types: BALF
  205. Silencing of TLR4 decreases liver tumor burden in a murine model of colorectal metastasis and hepatic steatosis.
    Authors: Earl TM, Nicoud IB, Pierce JM, Wright JP, Majoras NE, Rubin JE, Pierre KP, Gorden DL, Chari RS
    Ann. Surg. Oncol., 2009;16(4):1043-50.
    Species: Mouse
    Sample Types: Serum
  206. Beta-Arrestin2 regulates RANKL and ephrins gene expression in response to bone remodeling in mice.
    Authors: Pierroz DD, Rufo A, Bianchi EN, Glatt V, Capulli M, Rucci N, Cavat F, Rizzoli R, Teti A, Bouxsein ML, Ferrari SL
    J. Bone Miner. Res., 2009;24(5):775-84.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  207. Inhibitory effect of atractylenolide I on angiogenesis in chronic inflammation in vivo and in vitro.
    Authors: Wang C, Duan H, He L
    Eur. J. Pharmacol., 2009;612(1):143-52.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  208. Ethyl pyruvate administration inhibits hepatic tumor growth.
    Authors: Liang X, Chavez AR, Schapiro NE, Loughran P, Thorne SH, Amoscato AA, Zeh HJ, Beer-Stolz D, Lotze MT, de Vera ME
    J. Leukoc. Biol., 2009;86(3):599-607.
    Species: Mouse
    Sample Types: Plasma
  209. Plasminogen activator inhibitor-1 regulates neutrophil influx during acute pyelonephritis.
    Authors: Roelofs JJ, Teske GJ, Bonta PI, de Vries CJ, Meijers JC, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2009;75(1):52-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  210. Hypoxia-inducible factor-dependent induction of netrin-1 dampens inflammation caused by hypoxia.
    Authors: Rosenberger P, Schwab JM, Mirakaj V, Masekowsky E, Mager A, Morote-Garcia JC, Unertl K, Eltzschig HK
    Nat. Immunol., 2009;10(2):195-202.
    Species: Mouse
    Sample Types: Serum
  211. A MyD88-dependent early IL-17 production protects mice against airway infection with the obligate intracellular pathogen Chlamydia muridarum.
    Authors: Zhang X, Gao L, Lei L, Zhong Y, Dube P, Berton MT, Arulanandam B, Zhang J, Zhong G
    J. Immunol., 2009;183(2):1291-300.
    Species: Mouse
    Sample Types: BALF
  212. Reduction in dietary omega-6 polyunsaturated fatty acids: eicosapentaenoic acid plus docosahexaenoic acid ratio minimizes atherosclerotic lesion formation and inflammatory response in the LDL receptor null mouse.
    Authors: Wang S, Wu D, Matthan NR, Lamon-Fava S, Lecker JL, Lichtenstein AH
    Atherosclerosis, 2009;204(1):147-55.
    Species: Mouse
    Sample Types: Plasma
  213. C/EBPalpha is required for pulmonary cytoprotection during hyperoxia.
    Authors: Xu Y, Saegusa C, Schehr A, Grant S, Whitsett JA, Ikegami M
    Am. J. Physiol. Lung Cell Mol. Physiol., 2009;297(2):L286-98.
    Species: Mouse
    Sample Types: Tissue Homogenates
  214. A novel role for plasmin-mediated degradation of opsonizing antibody in the evasion of host immunity by virulent, but not attenuated, Francisella tularensis.
    Authors: Crane DD, Warner SL, Bosio CM
    J. Immunol., 2009;183(7):4593-600.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  215. Apelin prevents aortic aneurysm formation by inhibiting macrophage inflammation.
    Authors: Leeper NJ, Tedesco MM, Kojima Y, Schultz GM, Kundu RK, Ashley EA, Tsao PS, Dalman RL, Quertermous T
    Am. J. Physiol. Heart Circ. Physiol., 2009;296(5):H1329-35.
    Species: Mouse
    Sample Types: Serum
  216. VAMP8 is essential in anaphylatoxin-induced degranulation, TNF-alpha secretion, peritonitis, and systemic inflammation.
    Authors: Pushparaj PN, Tay HK, Wang CC, Hong W, Melendez AJ
    J. Immunol., 2009;183(2):1413-8.
    Species: Mouse
    Sample Types: Serum
  217. Differential IL-23 requirement for IL-22 and IL-17A production during innate immunity against Salmonella enterica serovar Enteritidis.
    Authors: Siegemund S, Schutze N, Schulz S, Wolk K, Nasilowska K, Straubinger RK, Sabat R, Alber G
    Int. Immunol., 2009;21(5):555-65.
    Species: Mouse
    Sample Types: Peritoneal Lavage
  218. Syndecan-1 shedding facilitates the resolution of neutrophilic inflammation by removing sequestered CXC chemokines.
    Authors: Hayashida K, Parks WC, Park PW
    Blood, 2009;114(14):3033-43.
    Species: Mouse
    Sample Types: Serum
  219. Urokinase plasminogen activator receptor-deficient mice demonstrate reduced hyperoxia-induced lung injury.
    Authors: van Zoelen MA, Florquin S, de Beer R, Pater JM, Verstege MI, Meijers JC, van der Poll T
    Am. J. Pathol., 2009;174(6):2182-9.
    Species: Mouse
    Sample Types: BALF
  220. Inhibition of monocyte-derived inflammatory cytokines by IL-25 occurs via p38 Map kinase-dependent induction of Socs-3.
    Authors: Caruso R, Stolfi C, Sarra M, Rizzo A, Fantini MC, Pallone F, MacDonald TT, Monteleone G
    Blood, 2009;113(15):3512-9.
    Species: Mouse
    Sample Types: Serum
  221. Modified adenine (9-benzyl-2-butoxy-8-hydroxyadenine) redirects Th2-mediated murine lung inflammation by triggering TLR7.
    Authors: Vultaggio A, Nencini F, Fitch PM, Fili L, Maggi L, Fanti P, deVries A, Beccastrini E, Palandri F, Manuelli C, Bani D, Giudizi MG, Guarna A, Annunziato F, Romagnani S, Maggi E, Howie SE, Parronchi P
    J. Immunol., 2009;182(2):880-9.
    Species: Mouse
    Sample Types: Serum
  222. Antifibrotic action of pirfenidone and prednisolone: different effects on pulmonary cytokines and growth factors in bleomycin-induced murine pulmonary fibrosis.
    Authors: Oku H, Shimizu T, Kawabata T, Nagira M, Hikita I, Ueyama A, Matsushima S, Torii M, Arimura A
    Eur. J. Pharmacol., 2008;590(1):400-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  223. Endogenous hydrogen sulfide regulates inflammatory response by activating the ERK pathway in polymicrobial sepsis.
    Authors: Zhang H, Moochhala SM, Bhatia M
    J. Immunol., 2008;181(6):4320-31.
    Species: Mouse
    Sample Types: Tissue Homogenates
  224. Functional roles for C5a receptors in sepsis.
    Authors: Rittirsch D, Flierl MA, Nadeau BA, Day DE, Huber-Lang M, Mackay CR, Zetoune FS, Gerard NP, Cianflone K, Kohl J, Gerard C, Sarma JV, Ward PA
    Nat. Med., 2008;14(5):551-7.
    Species: Mouse
    Sample Types: Plasma
  225. Adiponectin blocks multiple signaling cascades associated with leptin-induced cell proliferation in Apc Min/+ colon epithelial cells.
    Authors: Fenton JI, Birmingham JM, Hursting SD, Hord NG
    Int. J. Cancer, 2008;122(11):2437-45.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  226. Stem cell factor and its receptor, c-kit, are important for hepatocyte proliferation in wild-type and tumor necrosis factor receptor-1 knockout mice after 70% hepatectomy.
    Authors: Ren X, Hu B, Colletti L
    Surgery, 2008;143(6):790-802.
    Species: Mouse
    Sample Types: Tissue Homogenates
  227. Suppression of activation and induction of apoptosis in RAW264.7 cells by amniotic membrane extract.
    Authors: He H, Li W, Chen SY, Zhang S, Chen YT, Hayashida Y, Zhu YT, Tseng SC
    Invest. Ophthalmol. Vis. Sci., 2008;49(10):4468-75.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  228. Uncoupling of interleukin-6 from its signalling pathway by dietary n-3-polyunsaturated fatty acid deprivation alters sickness behaviour in mice.
    Authors: Mingam R, Moranis A, Bluthe RM, De Smedt-Peyrusse V, Kelley KW, Guesnet P, Lavialle M, Dantzer R, Laye S
    Eur. J. Neurosci., 2008;28(9):1877-86.
    Species: Mouse
    Sample Types: Plasma
  229. Identification of galectin-3-binding protein as a factor secreted by tumor cells that stimulates interleukin-6 expression in the bone marrow stroma.
    Authors: Fukaya Y, Shimada H, Wang LC, Zandi E, DeClerck YA
    J. Biol. Chem., 2008;283(27):18573-81.
    Species: Human
    Sample Types: Cell Culture Supernates
  230. The LTK63 adjuvant improves protection conferred by Ag85B DNA-protein prime-boosting vaccination against Mycobacterium tuberculosis infection by dampening IFN-gamma response.
    Authors: Palma C, Iona E, Giannoni F, Pardini M, Brunori L, Fattorini L, Del Giudice G, Cassone A
    Vaccine, 2008;26(33):4237-43.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  231. The neuropeptide substance P is a critical mediator of burn-induced acute lung injury.
    Authors: Sio SW, Puthia MK, Lu J, Moochhala S, Bhatia M
    J. Immunol., 2008;180(12):8333-41.
    Species: Mouse
    Sample Types: Tissue Homogenates
  232. Pharmacological IKK2 inhibition blocks liver steatosis and initiation of non-alcoholic steatohepatitis.
    Authors: Beraza N, Malato Y, Vander Borght S, Liedtke C, Wasmuth HE, Dreano M, De Vos R, Roskams T, Trautwein C
    Gut, 2008;57(5):655-63.
    Species: Mouse
    Sample Types: Tissue Homogenates
  233. Adverse functions of IL-17A in experimental sepsis.
    Authors: Flierl MA, Rittirsch D, Gao H, Hoesel LM, Nadeau BA, Day DE, Zetoune FS, Sarma JV, Huber-Lang MS, Ferrara JL, Ward PA
    FASEB J., 2008;22(7):2198-205.
    Species: Mouse
    Sample Types: Plasma
  234. The function of TRADD in signaling through tumor necrosis factor receptor 1 and TRIF-dependent Toll-like receptors.
    Authors: Pobezinskaya YL, Kim YS, Choksi S, Morgan MJ, Li T, Liu C, Liu Z
    Nat. Immunol., 2008;9(9):1047-54.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  235. The selective MMP-12 inhibitor, AS111793 reduces airway inflammation in mice exposed to cigarette smoke.
    Authors: Le Quement C, Guenon I, Gillon JY, Valenca S, Cayron-Elizondo V, Lagente V, Boichot E
    Br. J. Pharmacol., 2008;154(6):1206-15.
    Species: Mouse
    Sample Types: BALF
  236. Mouse models of rhinovirus-induced disease and exacerbation of allergic airway inflammation.
    Authors: Bartlett NW, Walton RP, Edwards MR, Aniscenko J, Caramori G, Zhu J, Glanville N, Choy KJ, Jourdan P, Burnet J, Tuthill TJ, Pedrick MS, Hurle MJ, Plumpton C, Sharp NA, Bussell JN, Swallow DM, Schwarze J, Guy B, Almond JW, Jeffery PK, Lloyd CM, Papi A, Killington RA, Rowlands DJ, Blair ED, Clarke NJ, Johnston SL
    Nat. Med., 2008;14(2):199-204.
    Species: Mouse
    Sample Types: BALF
  237. Dendritic cells derived from TBP-2-deficient mice are defective in inducing T cell responses.
    Authors: Son A, Nakamura H, Okuyama H, Oka S, Yoshihara E, Liu W, Matsuo Y, Kondo N, Masutani H, Ishii Y, Iyoda T, Inaba K, Yodoi J
    Eur. J. Immunol., 2008;38(5):1358-67.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  238. Low-dose acetylsalicylic acid inhibits the secretion of interleukin-6 from white adipose tissue.
    Authors: Ogston NC, Karastergiou K, Hosseinzadeh-Attar MJ, Bhome R, Madani R, Stables M, Gilroy D, Flachs P, Hensler M, Kopecky J, Mohamed-Ali V
    Int J Obes (Lond), 2008;32(12):1807-15.
  239. Fat diet and alcohol-induced steatohepatitis after LPS challenge in mice: role of bioactive TNF and Th1 type cytokines.
    Authors: Olleros ML, Martin ML, Vesin D, Fotio AL, Santiago-Raber ML, Rubbia-Brandt L, Spahr L, Hadengue A, Garcia I
    Cytokine, 2008;44(1):118-25.
    Species: Mouse
    Sample Types: Serum
  240. Inhibition of choroidal neovascularization with an anti-inflammatory carotenoid astaxanthin.
    Authors: Izumi-Nagai K, Nagai N, Ohgami K, Satofuka S, Ozawa Y, Tsubota K, Ohno S, Oike Y, Ishida S
    Invest. Ophthalmol. Vis. Sci., 2008;49(4):1679-85.
    Species: Mouse
    Sample Types: Tissue Homogenates
  241. Novel immunomodulatory properties of berbamine through selective down-regulation of STAT4 and action of IFN-gamma in experimental autoimmune encephalomyelitis.
    Authors: Ren Y, Lu L, Guo TB, Qiu J, Yang Y, Liu A, Zhang JZ
    J. Immunol., 2008;181(2):1491-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  242. Insulin-like growth factor-1 improves survival in sepsis via enhanced hepatic bacterial clearance.
    Authors: Ashare A, Nymon AB, Doerschug KC, Morrison JM, Monick MM, Hunninghake GW
    Am. J. Respir. Crit. Care Med., 2008;178(2):149-57.
    Species: Mouse
    Sample Types: Tissue Homogenates
  243. Cathelicidin-deficient (Cnlp -/- ) mice show increased susceptibility to Pseudomonas aeruginosa keratitis.
    Authors: Huang LC, Reins RY, Gallo RL, McDermott AM
    Invest. Ophthalmol. Vis. Sci., 2007;48(10):4498-508.
    Species: Mouse
    Sample Types: Tissue Homogenates
  244. IL-17 receptor signaling influences virus-induced corneal inflammation.
    Authors: Molesworth-Kenyon SJ, Yin R, Oakes JE, Lausch RN
    J. Leukoc. Biol., 2007;83(2):401-8.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  245. Maternal immune activation alters fetal brain development through interleukin-6.
    Authors: Smith SE, Li J, Garbett K, Mirnics K, Patterson PH
    J. Neurosci., 2007;27(40):10695-702.
    Species: Mouse
    Sample Types: Serum
  246. Clostridium sordellii lethal toxin kills mice by inducing a major increase in lung vascular permeability.
    Authors: Geny B, Khun H, Fitting C, Zarantonelli L, Mazuet C, Cayet N, Szatanik M, Prevost MC, Cavaillon JM, Huerre M, Popoff MR
    Am. J. Pathol., 2007;170(3):1003-17.
    Species: Mouse
    Sample Types: Tissue Homogenates
  247. Local stimulation of the adenosine A2B receptors induces an increased release of IL-6 in mouse striatum: an in vivo microdialysis study.
    Authors: Vazquez JF, Clement HW, Sommer O, Schulz E, van Calker D
    J. Neurochem., 2007;105(3):904-9.
    Species: Mouse
    Sample Types: Recombinant Protein
  248. Identification of an immune-responsive mesolimbocortical serotonergic system: potential role in regulation of emotional behavior.
    Authors: Lowry CA, Hollis JH, de Vries A, Pan B, Brunet LR, Hunt JR, Paton JF, van Kampen E, Knight DM, Evans AK, Rook GA, Lightman SL
    Neuroscience, 2007;146(2):756-72.
    Species: Mouse
    Sample Types: Plasma
  249. Toll-like receptor 4 mediates the early inflammatory response after cold ischemia/reperfusion.
    Authors: Kaczorowski DJ, Nakao A, Mollen KP, Vallabhaneni R, Sugimoto R, Kohmoto J, Tobita K, Zuckerbraun BS, McCurry KR, Murase N, Billiar TR
    Transplantation, 2007;84(10):1279-87.
    Species: Mouse
    Sample Types: Serum
  250. Acute brain injury triggers MyD88-dependent, TLR2/4-independent inflammatory responses.
    Authors: Koedel U, Merbt UM, Schmidt C, Angele B, Popp B, Wagner H, Pfister HW, Kirschning CJ
    Am. J. Pathol., 2007;171(1):200-13.
    Species: Mouse
    Sample Types: Tissue Homogenates
  251. CD40 and CD80/86 act synergistically to regulate inflammation and mortality in polymicrobial sepsis.
    Authors: Nolan A, Weiden M, Kelly A, Hoshino Y, Hoshino S, Mehta N, Gold JA
    Am. J. Respir. Crit. Care Med., 2007;177(3):301-8.
    Species: Mouse
    Sample Types: Plasma
  252. Metalloelastase (MMP-12) induced inflammatory response in mice airways: effects of dexamethasone, rolipram and marimastat.
    Authors: Nenan S, Lagente V, Planquois JM, Hitier S, Berna P, Bertrand CP, Boichot E
    Eur. J. Pharmacol., 2007;559(1):75-81.
    Species: Mouse
    Sample Types: Tissue Homogenates
  253. Chronic intranasal administration of mould spores or extracts to unsensitized mice leads to lung allergic inflammation, hyper-reactivity and remodelling.
    Authors: Denis O, van den Brule S, Heymans J, Havaux X, Rochard C, Huaux F, Huygen K
    Immunology, 2007;122(2):268-78.
    Species: Mouse
    Sample Types: BALF
  254. Cell-based angiopoietin-1 gene therapy for acute lung injury.
    Authors: McCarter SD, Mei SH, Lai PF, Zhang QW, Parker CH, Suen RS, Hood RD, Zhao YD, Deng Y, Han RN, Dumont DJ, Stewart DJ
    Am. J. Respir. Crit. Care Med., 2007;175(10):1014-26.
    Species: Mouse
    Sample Types: BALF
  255. Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock.
    Authors: Vogl T, Tenbrock K, Ludwig S, Leukert N, Ehrhardt C, van Zoelen MA, Nacken W, Foell D, van der Poll T, Sorg C, Roth J
    Nat. Med., 2007;13(9):1042-9.
    Species: Mouse
    Sample Types: Serum
  256. Capsaicin, a spicy component of hot peppers, modulates adipokine gene expression and protein release from obese-mouse adipose tissues and isolated adipocytes, and suppresses the inflammatory responses of adipose tissue macrophages.
    Authors: Kang JH, Kim CS, Han IS, Kawada T, Yu R
    FEBS Lett., 2007;581(23):4389-96.
    Species: Mouse
    Sample Types: Tissue Homogenates
  257. Entry route of Salmonella typhimurium directs the type of induced immune response.
    Authors: Martinoli C, Chiavelli A, Rescigno M
    Immunity, 2007;27(6):975-84.
    Species: Mouse
    Sample Types: Tissue Homogenates
  258. ST2 is essential for Th2 responsiveness and resistance to pseudomonas aeruginosa keratitis.
    Authors: Huang X, Du W, Barrett RP, Hazlett LD
    Invest. Ophthalmol. Vis. Sci., 2007;48(10):4626-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  259. Multiple circulating proangiogenic factors induced by sunitinib malate are tumor-independent and correlate with antitumor efficacy.
    Authors: Ebos JM, Lee CR, Christensen JG, Mutsaers AJ, Kerbel RS
    Proc. Natl. Acad. Sci. U.S.A., 2007;104(43):17069-74.
    Species: Mouse
    Sample Types: Plasma
  260. Astragali Radix elicits anti-inflammation via activation of MKP-1, concomitant with attenuation of p38 and Erk.
    Authors: Ryu M, Kim EH, Chun M, Kang S, Shim B, Yu YB, Jeong G, Lee JS
    J Ethnopharmacol, 2007;115(2):184-93.
    Species: Mouse
    Sample Types: Air Pouch Exudate
  261. Neuronal NF-kappaB influences thermoregulation and survival in a sepsis model.
    Authors: Juttler E, Inta I, Eigler V, Herrmann O, Maegele I, Maser-Gluth C, Schwaninger M
    J. Neuroimmunol., 2007;189(1):41-9.
    Species: Mouse
    Sample Types: Serum
  262. Inactivated Sendai virus particles eradicate tumors by inducing immune responses through blocking regulatory T cells.
    Authors: Kurooka M, Kaneda Y
    Cancer Res., 2007;67(1):227-36.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  263. CD44 regulates macrophage recruitment to the lung in lipopolysaccharide-induced airway disease.
    Authors: Hollingsworth JW, Li Z, Brass DM, Garantziotis S, Timberlake SH, Kim A, Hossain I, Savani RC, Schwartz DA
    Am. J. Respir. Cell Mol. Biol., 2007;37(2):248-53.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  264. Interleukin-1beta is the primary initiator of pulmonary inflammation following liver injury in mice.
    Authors: Glasgow SC, Ramachandran S, Blackwell TS, Mohanakumar T, Chapman WC
    Am. J. Physiol. Lung Cell Mol. Physiol., 2007;293(2):L491-6.
    Species: Mouse
    Sample Types: Serum
  265. The direct action of 1alpha,25(OH)2-vitamin D3 on purified mouse Langerhans cells.
    Authors: Fujita H, Asahina A, Komine M, Tamaki K
    Cell. Immunol., 2007;245(2):70-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  266. Effect of chronic IL-6 infusion on acute pressor responses to vasoconstrictors in mice.
    Authors: Boesen EI, Pollock DM
    Am. J. Physiol. Heart Circ. Physiol., 2007;293(3):H1745-9.
    Species: Mouse
    Sample Types: Plasma
  267. Graft produced interleukin-6 functions as a danger signal and promotes rejection after transplantation.
    Authors: Liang Y, Christopher K, Finn PW, Colson YL, Perkins DL
    Transplantation, 2007;84(6):771-7.
    Species: Mouse
    Sample Types: Serum
  268. The immunomodulation of endotoxin-induced acute lung injury by hesperidin in vivo and in vitro.
    Authors: Yeh CC, Kao SJ, Lin CC, Wang SD, Liu CJ, Kao ST
    Life Sci., 2007;80(20):1821-31.
    Species: Mouse
    Sample Types: BALF
  269. Regulation of systemic and local neutrophil responses by G-CSF during pulmonary Pseudomonas aeruginosa infection.
    Authors: Gregory AD, Hogue LA, Ferkol TW, Link DC
    Blood, 2007;109(8):3235-43.
    Species: Mouse
    Sample Types: Epithelial Fluid
  270. TLR2 is constitutively expressed within the kidney and participates in ischemic renal injury through both MyD88-dependent and -independent pathways.
    Authors: Shigeoka AA, Holscher TD, King AJ, Hall FW, Kiosses WB, Tobias PS, Mackman N, McKay DB
    J. Immunol., 2007;178(10):6252-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  271. Persistent effects induced by IL-13 in the lung.
    Authors: Fulkerson PC, Fischetti CA, Hassman LM, Nikolaidis NM, Rothenberg ME
    Am. J. Respir. Cell Mol. Biol., 2006;35(3):337-46.
    Species: Mouse
    Sample Types: BALF
  272. Induction of dendritic cell maturation by pertussis toxin and its B subunit differentially initiate Toll-like receptor 4-dependent signal transduction pathways.
    Authors: Wang ZY, Yang D, Chen Q, Leifer CA, Segal DM, Su SB, Caspi RR, Howard ZO, Oppenheim JJ
    Exp. Hematol., 2006;34(8):1115-24.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  273. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
    Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1246-55.
    Species: Mouse
    Sample Types: Tissue Homogenates
  274. MAPKAP kinase 2-deficient mice are resistant to collagen-induced arthritis.
    Authors: Hegen M, Gaestel M, Nickerson-Nutter CL, Lin LL, Telliez JB
    J. Immunol., 2006;177(3):1913-7.
    Species: Mouse
    Sample Types: Serum
  275. Bim deficiency leads to exacerbation and prolongation of joint inflammation in experimental arthritis.
    Authors: Scatizzi JC, Bickel E, Hutcheson J, Haines GK, Perlman H
    Arthritis Rheum., 2006;54(10):3182-93.
    Species: Mouse
    Sample Types: Tissue Homogenates
  276. A coagulation factor VII deficiency protects against acute inflammatory responses in mice.
    Authors: Xu H, Ploplis VA, Castellino FJ
    J. Pathol., 2006;210(4):488-96.
    Species: Mouse
    Sample Types: Plasma
  277. Rubus coreanus Miq. extract promotes osteoblast differentiation and inhibits bone-resorbing mediators in MC3T3-E1 cells.
    Authors: Lee KH, Choi EM
    Am. J. Chin. Med., 2006;34(4):643-54.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  278. Protease-activated receptor-2 activation: a major role in the pathogenesis of Porphyromonas gingivalis infection.
    Authors: Holzhausen M, Spolidorio LC, Ellen RP, Jobin MC, Steinhoff M, Andrade-Gordon P, Vergnolle N
    Am. J. Pathol., 2006;168(4):1189-99.
    Species: Mouse
    Sample Types: Blister Fluid
  279. The urokinase plasminogen activator receptor is crucially involved in host defense during acute pyelonephritis.
    Authors: Roelofs JJ, Rouschop KM, Teske GJ, Claessen N, Weening JJ, van der Poll T, Florquin S
    Kidney Int., 2006;70(11):1942-7.
    Species: Mouse
    Sample Types: Tissue Homogenates
  280. Delayed inflammatory responses to endotoxin in fibrinogen-deficient mice.
    Authors: Cruz-Topete D, Iwaki T, Ploplis VA, Castellino FJ
    J. Pathol., 2006;210(3):325-33.
    Species: Mouse
    Sample Types: Plasma
  281. CD27 contributes to the early systemic immune response to Mycobacterium tuberculosis infection but does not affect outcome.
    Authors: Wieland CW, Kerver ME, Florquin S, Nolte MA, Borst J, van Lier R, van Oers MH, van der Poll T
    Int. Immunol., 2006;18(11):1531-9.
    Species: Mouse
    Sample Types: Tissue Homogenates
  282. Allergic airway inflammation inhibits pulmonary antibacterial host defense.
    Authors: Beisswenger C, Kandler K, Hess C, Garn H, Felgentreff K, Wegmann M, Renz H, Vogelmeier C, Bals R
    J. Immunol., 2006;177(3):1833-7.
    Species: Mouse
    Sample Types: BALF
  283. Roles of the small intestine for induction of toll-like receptor 4-mediated innate resistance in naturally acquired murine toxoplasmosis.
    Authors: Furuta T, Yoshikawa Y
    Int. Immunol., 2006;18(12):1655-62.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  284. Vaccinia virus infection attenuates innate immune responses and antigen presentation by epidermal dendritic cells.
    Authors: Deng L, Dai P, Ding W, Granstein RD, Shuman S
    J. Virol., 2006;80(20):9977-87.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  285. Organ-specific role of MyD88 for gene regulation during polymicrobial peritonitis.
    Authors: Weighardt H, Mages J, Jusek G, Kaiser-Moore S, Lang R, Holzmann B
    Infect. Immun., 2006;74(6):3618-32.
    Species: Mouse
    Sample Types: Tissue Homogenates
  286. Altered postnatal lung development in C3H/HeJ mice.
    Authors: Sampath V, Davis K, Senft AP, Richardson TR, Kitzmiller JA, Berclaz PY, Korfhagen TR
    Pediatr. Res., 2006;60(6):663-8.
    Species: Mouse
    Sample Types: Tissue Homogenates
  287. Impact of the loss of Hoxa5 function on lung alveogenesis.
    Authors: Mandeville I, Aubin J, Leblanc M, Lalancette-Hebert M, Janelle MF, Tremblay GM, Jeannotte L
    Am. J. Pathol., 2006;169(4):1312-27.
    Species: Mouse
    Sample Types: BALF
  288. Citrus polymethoxylated flavones improve lipid and glucose homeostasis and modulate adipocytokines in fructose-induced insulin resistant hamsters.
    Authors: Li RW, Theriault AG, Au K, Douglas TD, Casaschi A, Kurowska EM, Mukherjee R
    Life Sci., 2006;79(4):365-73.
    Species: Mouse
    Sample Types: Serum
  289. The pulmonary and hepatic immune microenvironment and its contribution to the early systemic inflammation following blunt chest trauma.
    Authors: Perl M, Gebhard F, Braumuller S, Tauchmann B, Bruckner UB, Kinzl L, Knoferl MW
    Crit. Care Med., 2006;34(4):1152-9.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  290. Prostaglandin D2 mediates neuronal damage by amyloid-beta or prions which activates microglial cells.
    Authors: Bate C, Kempster S, Williams A
    Neuropharmacology, 2006;50(2):229-37.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  291. Adenosine A2A receptor inactivation increases survival in polymicrobial sepsis.
    Authors: Nemeth ZH, Csoka B, Wilmanski J, Xu D, Lu Q, Ledent C, Deitch EA, Pacher P, Spolarics Z, Hasko G
    J. Immunol., 2006;176(9):5616-26.
    Species: Mouse
    Sample Types: Plasma
  292. Gender differences in murine airway responsiveness and lipopolysaccharide-induced inflammation.
    Authors: Card JW, Carey MA, Bradbury JA, DeGraff LM, Morgan DL, Moorman MP, Flake GP, Zeldin DC
    J. Immunol., 2006;177(1):621-30.
    Species: Mouse
    Sample Types: BALF
  293. A novel polysaccharide of black soybean promotes myelopoiesis and reconstitutes bone marrow after 5-flurouracil- and irradiation-induced myelosuppression.
    Authors: Liao HF, Chen YJ, Yang YC
    Life Sci., 2005;77(4):400-13.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  294. Interleukin-17 as a recruitment and survival factor for airway macrophages in allergic airway inflammation.
    Authors: Sergejeva S, Ivanov S, Lotvall J, Linden A
    Am. J. Respir. Cell Mol. Biol., 2005;33(3):248-53.
    Species: Mouse
    Sample Types: BALF
  295. Inhibition of colony-stimulating-factor-1 signaling in vivo with the orally bioavailable cFMS kinase inhibitor GW2580.
    Authors: Conway JG, Conway&lt;/LastName&gt;&lt;ForeNam JG&lt;/Initia, McDonald B, Parham J, Keith B, Rusnak DW, Shaw E, Jansen M, Lin P, Payne A, Crosby RM, Johnson JH, Frick L, Lin MH, Depee S, Tadepalli S, Votta B, James I, Fuller K, Chambers TJ, Kull FC, Chamberlain SD, Hutchins JT
    Proc. Natl. Acad. Sci. U.S.A., 2005;102(44):16078-83.
    Species: Mouse
    Sample Types: Plasma
  296. A distinct and unique transcriptional program expressed by tumor-associated macrophages (defective NF-kappaB and enhanced IRF-3/STAT1 activation).
    Authors: Biswas SK, Gangi L, Paul S, Schioppa T, Saccani A, Sironi M, Bottazzi B, Doni A, Vincenzo B, Pasqualini F, Vago L, Nebuloni M, Mantovani A, Sica A
    Blood, 2005;107(5):2112-22.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  297. Systemic up-regulation of sTNFR2 and IL-6 in Porphyromonas gingivalis pneumonia in mice.
    Authors: Petelin M, Naruishi K, Shiomi N, Mineshiba J, Arai H, Nishimura F, Takashiba S, Murayama Y
    Exp. Mol. Pathol., 2004;76(1):76-81.
    Species: Mouse
    Sample Types: Serum
  298. T cell-specific ablation of Fas leads to Fas ligand-mediated lymphocyte depletion and inflammatory pulmonary fibrosis.
    Authors: Hao Z, Hampel B, Yagita H, Rajewsky K
    J. Exp. Med., 2004;199(10):1355-65.
    Species: Mouse
    Sample Types: Serum
  299. Increased interleukin-10 associated with low IL-6 concentration correlated with greater survival rates in mice infected by rabies virus vaccinated against it and immunomodulated with P. acnes.
    Authors: Megid J, Kaneno R, Nozaki CN, Brito CJ, Almeida MF
    Comp. Immunol. Microbiol. Infect. Dis., 2004;27(6):393-411.
    Species: Mouse
    Sample Types: Serum
  300. IL-22 increases the innate immunity of tissues.
    Authors: Wolk K, Kunz S, Witte E, Friedrich M, Asadullah K, Sabat R
    Immunity, 2004;21(2):241-54.
    Species: Mouse
    Sample Types: Plasma
  301. Regulation of Pseudomonas aeruginosa corneal infection in IL-1 beta converting enzyme (ICE, caspase-1) deficient mice.
    Authors: Thakur A, Barrett RP, McClellan S, Hazlett LD
    Curr. Eye Res., 2004;29(4):225-33.
    Species: Mouse
    Sample Types: Tissue Homogenates
  302. Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
    Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
    J. Immunol., 2004;172(12):7408-16.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  303. Endogenous IL-17 as a mediator of neutrophil recruitment caused by endotoxin exposure in mouse airways.
    Authors: Miyamoto M, Prause O, Sjostrand M, Laan M, Lotvall J, Linden A
    J. Immunol., 2003;170(9):4665-72.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  304. Intra-amniotic lipopolysaccharide leads to fetal cardiac dysfunction. A mouse model for fetal inflammatory response.
    Authors: Rounioja S, Rasanen J, Glumoff V, Ojaniemi M, Makikallio K, Hallman M
    Cardiovasc. Res., 2003;60(1):156-64.
    Species: Mouse
    Sample Types: Amniotic Fluid
  305. Role of tissue factor and protease-activated receptors in a mouse model of endotoxemia.
    Authors: Pawlinski R, Pedersen B, Schabbauer G, Tencati M, Holscher T, Boisvert W, Andrade-Gordon P, Frank RD, Mackman N
    Blood, 2003;103(4):1342-7.
    Species: Mouse
    Sample Types: Plasma
  306. Interplay between IFN-gamma and IL-6 signaling governs neutrophil trafficking and apoptosis during acute inflammation.
    Authors: McLoughlin RM, Witowski J, Robson RL, Wilkinson TS, Hurst SM, Williams AS, Williams JD, Rose-John S, Jones SA, Topley N
    J. Clin. Invest., 2003;112(4):598-607.
    Species: Mouse
    Sample Types: Peritoneal Fluid
  307. Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function.
    Authors: Miller G, Pillarisetty VG, Shah AB, Lahrs S, Xing Z, DeMatteo RP
    J. Immunol., 2002;169(6):2875-85.
    Species: Mouse
    Sample Types: Serum
  308. The protein tyrosine kinase inhibitor AG126 prevents the massive microglial cytokine induction by pneumococcal cell walls.
    Authors: Hanisch UK, Prinz M, Angstwurm K, Hausler KG, Kann O, Kettenmann H, Weber JR
    Eur. J. Immunol., 2001;31(7):2104-15.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  309. A secreted and LIF-mediated stromal cell-derived activity that promotes ex vivo expansion of human hematopoietic stem cells.
    Authors: Shih CC, Hu MC, Hu J
    Blood, 2000;95(6):1957-66.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  310. Interleukin-6 and the granulocyte colony-stimulating factor receptor are major independent regulators of granulopoiesis in vivo but are not required for lineage commitment or terminal differentiation.
    Authors: Liu F, Poursine-Laurent J, Wu HY, Link DC
    Blood, 1997;90(7):2583-90.
    Species: Mouse
    Sample Types: Serum
  311. Biglycan, a danger signal that activates the NLRP3 inflammasome via toll-like and P2X receptors.
    Authors: Babelova A, Moreth K, Tsalastra-Greul W, Zeng-Brouwers J, Eickelberg O, Young MF, Bruckner P, Pfeilschifter J, Schaefer RM, Schaefer R, Grone HJ, Schaefer L
    J Biol Chem, 0;284(36):24035-48.
    Species: Mouse
    Sample Types: Plasma

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Reviews for Mouse IL-6 Quantikine ELISA Kit

Average Rating: 4.7 (Based on 6 Reviews)

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Mouse IL-6 Quantikine ELISA Kit
By Anonymous on 08/06/2018
Sample Tested: Cell Culture Supernates

Mouse IL-6 Quantikine ELISA Kit
By Anonymous on 04/18/2018
Sample Tested: LL/2 mouse Lewis lung carcinoma cell line

Mouse IL-6 Quantikine ELISA Kit
By Anonymous on 04/02/2018
Sample Tested: mouse pancreatic cancer tissue

Mouse IL-6 Quantikine ELISA Kit
By Anonymous on 09/01/2017
Sample Tested: Brain tissue

Mouse IL-6 Quantikine ELISA Kit
By Anonymous on 07/19/2017
Sample Tested: Serum,Brain (cortex) tissue

Just wanted to let anyone know that the second kit used worked flawless compared to the review I posted above.


Mouse IL-6 Quantikine ELISA Kit
By Anonymous on 07/15/2016
Sample Tested: Serum,Liver tissue,Brain (cerebral cortex),choroid plexus,Adipose tissue

One plate performed really good but one plate turned out blank. The costumer support were really helpful with diagnosing the error. Attached you find a photo of the plate that didn't work out: