Mouse Integrin beta 6 Antibody

Catalog #: AF2389
6 Citations Datasheet / COA / SDS

Catalog #	Availability	Size / Price	Qty
AF2389
AF2389-SP

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Product Details

Citations (6)

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Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse Integrin beta 6 Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse Integrin beta 6 in direct ELISAs and Western blots.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Chinese hamster ovary cell line CHO-derived recombinant mouse Integrin beta 6
Gly22-Asn706
Accession # Q9Z0T9

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse Integrin beta 6

Immunocytochemistry

5-15 µg/mL

Immersion fixed mouse splenocytes

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available

Reconstitution Buffer 1 (PBS)

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: Integrin beta 6

Integrin beta 6 is a type I transmembrane Integrin beta subunit that heterodimerizes with alpha V subunits in the epithelial restricted integrin alpha V/ beta 6. The extracellular domain of mouse Integrin beta 6 contains a collagen binding von-Willebrand factor A domain and multiple truncated EGF-like motifs. Mouse Integrin beta 6 extracellular domain shares 96% and 91% amino acid sequence identity with the corresponding regions of the rat and human protein, respectively.

Entrez Gene IDs

3694 (Human); 16420 (Mouse); 311061 (Rat); 102122296 (Cynomolgus Monkey)

Alternate Names

Integrin beta 6; integrin beta-6; integrin, beta 6; ITGB6

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

Citations for Mouse Integrin beta 6 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

6 Citations: Showing 1 - 6
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The NOGO receptor NgR2, a novel alphaVbeta3 integrin effector, induces neuroendocrine differentiation in prostate cancer
Authors: F Quaglia, SR Krishn, K Sossey-Ala, PS Rana, E Pluskota, PH Park, CD Shields, S Lin, P McCue, AV Kossenkov, Y Wang, DW Goodrich, SY Ku, H Beltran, WK Kelly, E Corey, M Klose, C Bandtlow, Q Liu, DC Altieri, EF Plow, LR Languino
Scientific Reports, 2022-11-07;12(1):18879.
Species: Human
Sample Types: Protein
Applications: Western Blot
Podocyte-specific KLF4 is required to maintain parietal epithelial cell quiescence in the kidney
Authors: JA Pace, R Bronstein, Y Guo, Y Yang, CC Estrada, N Gujarati, DJ Salant, J Haley, AB Bialkowska, VW Yang, JC He, SK Mallipattu
Science Advances, 2021-09-03;7(36):eabg6600.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC
Myofibroblast induces hepatocyte-to-ductal metaplasia via laminin-?v&beta6 integrin in liver fibrosis
Authors: T Xu, Z Lu, Z Xiao, F Liu, Y Chen, Z Wang, S Zhu, Y Song
Cell Death Dis, 2020-03-23;11(3):199.
Species: Mouse
Sample Types: Whole Cells
Applications: ICC
Suppression of ?v?6 Integrin Expression by Polymicrobial Oral Biofilms in Gingival Epithelial Cells
Authors: J Bi, L Koivisto, A Pang, M Li, G Jiang, S Aurora, Z Wang, GR Owen, J Dai, Y Shen, D Grenier, M Haapasalo, L Häkkinen, H Larjava
Sci Rep, 2017-06-30;7(1):4411.
Species: Human
Sample Types: Cell Lysates
Applications: Western Blot
Critical role for alphavbeta6 integrin in enamel biomineralization.
Authors: Mohazab L, Koivisto L, Jiang G, Kytomaki L, Haapasalo M, Owen G, Wiebe C, Xie Y, Heikinheimo K, Yoshida T, Smith C, Heino J, Hakkinen L, McKee M, Larjava H
J Cell Sci, 2012-12-21;126(0):732-44.
Species: Mouse
Sample Types: Tissue Homogenates
Applications: Western Blot
Lunatic Fringe-mediated Notch signaling is required for lung alveogenesis.
Authors: Xu K, Nieuwenhuis E, Cohen BL, Wang W, Canty AJ, Danska JS, Coultas L, Rossant J, Wu MY, Piscione TD, Nagy A, Gossler A, Hicks GG, Hui CC, Henkelman RM, Yu LX, Sled JG, Gridley T, Egan SE
Am. J. Physiol. Lung Cell Mol. Physiol., 2009-11-06;298(1):L45-56.
Species: Mouse
Sample Types: Tissue Homogenates, Whole Tissue
Applications: IHC-P, Western Blot