Mouse SCGF/CLEC11a Antibody

Catalog #: AF3729
3 Citations Datasheet / COA / SDS

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AF3729
AF3729-SP

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Product Details

Citations (3)

Supplemental Products

Reviews

Summary Preparation and Storage Reconstitution Calculator Background Product Datasheets Related Research Areas

Mouse SCGF/CLEC11a Antibody Summary

Species Reactivity

Mouse

Specificity

Detects mouse SCGF/CLEC11a in direct ELISAs and Western blots. In direct ELISAs and Western blots, less than 2% cross-reactivity with recombinant human SCGF is observed.

Source

Polyclonal Goat IgG

Purification

Antigen Affinity-purified

Immunogen

Mouse myeloma cell line NS0-derived recombinant mouse SCGF/CLEC11a
Ala22-Phe328
Accession # O88200

Formulation

Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.

Label

Unconjugated

Applications

Recommended Concentration

Sample

Western Blot

0.1 µg/mL

Recombinant Mouse SCGF/CLEC11a

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

Reconstitution Calculator

Preparation and Storage

Reconstitution

Reconstitute at 0.2 mg/mL in sterile PBS.

Reconstitution Buffer Available

Reconstitution Buffer 1 (PBS)

Shipping

The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C

Stability & Storage

Use a manual defrost freezer and avoid repeated freeze-thaw cycles.

12 months from date of receipt, -20 to -70 °C as supplied.
1 month, 2 to 8 °C under sterile conditions after reconstitution.
6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: SCGF/CLEC11a

SCGF, also named CLEC11a, is a 47 kDa, 328 amino acid, secreted glycoprotein member of the C-type lectin superfamily. Produced by CD33⁺ stem cells and resting chondrocytes, SCGF acts in combination with other factors to promote erythroid, myeloid and endothelial cell production. Over the region used as immunogen, mouse SCGF is 92% and 83% aa identical to the corresponding rat and human protein sequences, respectively.

Long Name

Stem Cell Growth Factor/C-type Lectin Domain Family 11, Member A

Entrez Gene IDs

6320 (Human); 20256 (Mouse); 29313 (Rat)

Alternate Names

CLEC11a; CLECSF3; LSLCL; P47; SCGF

Product Datasheets

Product Datasheet

COA

SDS

Related Research Areas

C-type Lectin Family

Citations for Mouse SCGF/CLEC11a Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

3 Citations: Showing 1 - 3
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Identification of Fibroblast Activation Protein as an Osteogenic Suppressor and Anti-osteoporosis Drug Target
Authors: H Wei, Y Xu, Y Wang, L Xu, C Mo, L Li, B Shen, Y Sun, P Cheng, L Yang, Y Pang, A Qin, Y Cao, SJ Morrison, R Yue
Cell Rep, 2020-10-13;33(2):108252.
Species: Mouse
Sample Types: Whole Tissue
Applications: IHC
Chronic activation of endothelial MAPK disrupts hematopoiesis via NFKB dependent inflammatory stress reversible by SCGF
Authors: P Ramalingam, MG Poulos, E Lazzari, MC Gutkin, D Lopez, CC Kloss, MJ Crowley, L Katsnelson, AG Freire, MB Greenblatt, CY Park, JM Butler
Nat Commun, 2020-02-03;11(1):666.
Species: Mouse
Sample Types: Plasma
Applications: ELISA (detection)
Human umbilical cord mesenchymal stromal cells-derived extracellular vesicles exert potent bone protective effects by CLEC11A-mediated regulation of bone metabolism
Authors: Y Hu, Y Zhang, CY Ni, CY Chen, SS Rao, H Yin, J Huang, YJ Tan, ZX Wang, J Cao, ZZ Liu, PL Xie, B Wu, J Luo, H Xie
Theranostics, 2020-01-16;10(5):2293-2308.
Species: Mouse
Sample Types: Cell Culture Lysates
Applications: Western Blot