Mouse VE-Statin Isoform 1 Antibody

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Product Details
Citations (1)
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Mouse VE-Statin Isoform 1 Antibody Summary

Species Reactivity
Detects mouse VE-Statin Isoform 1 in direct ELISAs and Western blots. In Western blots, approximately 10% cross-reactivity with recombinant human VE-Statin is observed.
Polyclonal Goat IgG
Antigen Affinity-purified
E. coli-derived recombinant mouse VE-Statin Isoform 1
Accession # Q9QXT5
Lyophilized from a 0.2 μm filtered solution in PBS with Trehalose. *Small pack size (SP) is supplied either lyophilized or as a 0.2 µm filtered solution in PBS.


Recommended Concentration
Western Blot
0.1 µg/mL
Recombinant Mouse VE-Statin Isoform 1

Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.

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Preparation and Storage

Reconstitute at 0.2 mg/mL in sterile PBS.
The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below. *Small pack size (SP) is shipped with polar packs. Upon receipt, store it immediately at -20 to -70 °C
Stability & Storage
Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 6 months, -20 to -70 °C under sterile conditions after reconstitution.

Background: VE-Statin

Mouse VE-Statin (vascular endothelial cell statin; also EGFL7) is a secreted glycoprotein that belongs to an expanding family of EGF-like domain-containing proteins. It typically runs at 33-36 kDa in SDS-PAGE.  Higher molecular weight monomers ranging from 40-42 kDa have also been reported, and suggested to be a consequence of O-linked glycosylation.  VE-Statin is an early marker of embryonic endothelial cells, and occurs in adult endothelium. Its secretion blocks smooth muscle migration. The mature molecule is 254 amino acids (aa) in length, and contains one N-terminal EMI domain (aa 28‑105), two EGF-like domains (aa 106‑178), and a coiled‑coil region (aa 196‑220). There is at least one isoform that shows a 13 aa deletion between aa 236‑248. Mature mouse VE-statin shares 76% and 80% aa sequence identity with dog and human VE‑statin, respectively.

Long Name
Vascular Endothelial Statin/EGF-like Domain, Multiple 7
Entrez Gene IDs
51162 (Human)
Alternate Names
EGFL7; EGF-like protein 7; EGF-like-domain, multiple 7; epidermal growth factor-like protein 7; MEGF7; MGC111117; Multiple EGF-like domains protein 7; Multiple epidermal growth factor-like domains protein 7; NEU1 protein; NOTCH4-like protein; RP11-251M1.2; Vascular endothelial statin; VEStatin; VE-Statin; ZNEU1

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Citation for Mouse VE-Statin Isoform 1 Antibody

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

1 Citation: Showing 1 - 1

  1. EGFL7 enhances surface expression of integrin ?5?1 to promote angiogenesis in malignant brain tumors
    Authors: N Dudvarski, F Bicker, S Keller, DT Jones, PN Harter, A Kienzle, C Gillmann, P Arnold, A Golebiewsk, O Keunen, A Giese, A von Deimli, T Bäuerle, SP Niclou, M Mittelbron, W Ye, SM Pfister, MH Schmidt
    EMBO Mol Med, 2018-09-01;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: IHC-P


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