Mouse VE-Statin Isoform 1 Antibody
Mouse VE-Statin Isoform 1 Antibody Summary
Accession # Q9QXT5
Please Note: Optimal dilutions should be determined by each laboratory for each application. General Protocols are available in the Technical Information section on our website.
Preparation and Storage
- 12 months from date of receipt, -20 to -70 °C as supplied.
- 1 month, 2 to 8 °C under sterile conditions after reconstitution.
- 6 months, -20 to -70 °C under sterile conditions after reconstitution.
Mouse VE-Statin (vascular endothelial cell statin; also EGFL7) is a secreted glycoprotein that belongs to an expanding family of EGF-like domain-containing proteins. It typically runs at 33-36 kDa in SDS-PAGE. Higher molecular weight monomers ranging from 40-42 kDa have also been reported, and suggested to be a consequence of O-linked glycosylation. VE-Statin is an early marker of embryonic endothelial cells, and occurs in adult endothelium. Its secretion blocks smooth muscle migration. The mature molecule is 254 amino acids (aa) in length, and contains one N-terminal EMI domain (aa 28‑105), two EGF-like domains (aa 106‑178), and a coiled‑coil region (aa 196‑220). There is at least one isoform that shows a 13 aa deletion between aa 236‑248. Mature mouse VE-statin shares 76% and 80% aa sequence identity with dog and human VE‑statin, respectively.
Citation for Mouse VE-Statin Isoform 1 Antibody
R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.
1 Citation: Showing 1 - 1
EGFL7 enhances surface expression of integrin ?5?1 to promote angiogenesis in malignant brain tumors
Authors: N Dudvarski, F Bicker, S Keller, DT Jones, PN Harter, A Kienzle, C Gillmann, P Arnold, A Golebiewsk, O Keunen, A Giese, A von Deimli, T Bäuerle, SP Niclou, M Mittelbron, W Ye, SM Pfister, MH Schmidt
EMBO Mol Med, 2018;0(0):.
Sample Types: Whole Tissue
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