Phospho-Akt (S473) Pan Specific Surveyor IC
Phospho-Akt (S473) Pan Specific Surveyor IC Summary
Preparation and Storage
Akt1, Akt2, and Akt3 make up a family of serine/threonine kinases, often activated downstream of growth factor receptors and PI 3-Kinase. Each Akt family member contains an N-terminal pleckstrin homology (PH) domain, a central kinase domain, and a C-terminal regulatory domain. They have putative roles in cell proliferation and survival, and Akt perturbations are thought to play an important role in tumorigenesis.
Citations for Phospho-Akt (S473) Pan Specific Surveyor IC
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Gene network analysis of bone marrow mononuclear cells reveals activation of multiple kinase pathways in human systemic lupus erythematosus.
Authors: Nakou M, Bertsias G, Stagakis I
PLoS ONE, 2010;5(10):e13351. 2010
Ras-induced modulation of CXCL10 and its receptor splice variant CXCR3-B in MDA-MB-435 and MCF-7 cells: relevance for the development of human breast cancer.
Authors: Datta D, Flaxenburg JA, Laxmanan S, Geehan C, Grimm M, Waaga-Gasser AM, Briscoe DM, Pal S
Cancer Res., 2006;66(19):9509-18. 2006
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