Recombinant Mouse TNF-alpha (aa 80-235) Protein

Formulations:
Catalog # Availability Size / Price Qty
410-MT-010
410-MT-050
410-MT-025
410-MT-100
410-MT-01M
Product Details
Citations (201)
FAQs
Supplemental Products
Reviews (6)

Recombinant Mouse TNF-alpha (aa 80-235) Protein Summary

Purity
>97%, by SDS-PAGE under reducing conditions and visualized by silver stain.
Endotoxin Level
<0.01 EU per 1 μg of the protein by the LAL method.
Activity
Measured in a cytotoxicity assay using L‑929 mouse fibroblast cells in the presence of the metabolic inhibitor actinomycin D. Matthews, N. and M.L. Neale (1987) in Lymphokines and Interferons, A Practical Approach. Clemens, M.J. et al. (eds): IRL Press. 221. The ED50 for this effect is 0.008-0.05 ng/mL.
Source
E. coli-derived mouse TNF-alpha protein
Leu80-Leu235, with an N-terminal Met
Accession #
N-terminal Sequence
Analysis
Met & Ser84
Structure / Form
A small amount of recombinant protein lacking the N-terminal methionine and four additional amino acid residues may be also present.
Predicted Molecular Mass
17 kDa

Product Datasheets

Carrier Free

What does CF mean?

CF stands for Carrier Free (CF). We typically add Bovine Serum Albumin (BSA) as a carrier protein to our recombinant proteins. Adding a carrier protein enhances protein stability, increases shelf-life, and allows the recombinant protein to be stored at a more dilute concentration. The carrier free version does not contain BSA.

What formulation is right for me?

In general, we advise purchasing the recombinant protein with BSA for use in cell or tissue culture, or as an ELISA standard. In contrast, the carrier free protein is recommended for applications, in which the presence of BSA could interfere.

410-MT

Formulation Lyophilized from a 0.2 μm filtered solution in PBS with BSA as a carrier protein. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS with BSA as a carrier protein.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS containing at least 0.1% human or bovine serum albumin.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.

410-MT/CF

Formulation Lyophilized from a 0.2 μm filtered solution in PBS. *1 mg pack size (01M) is supplied as a 0.2 µm filtered solution in PBS.
Reconstitution Reconstitute at 100 μg/mL in sterile PBS.
Shipping The product is shipped at ambient temperature. Upon receipt, store it immediately at the temperature recommended below.
Stability & Storage: Use a manual defrost freezer and avoid repeated freeze-thaw cycles.
  • 12 months from date of receipt, -20 to -70 °C as supplied.
  • 1 month, 2 to 8 °C under sterile conditions after reconstitution.
  • 3 months, -20 to -70 °C under sterile conditions after reconstitution.
Reconstitution Calculator

Reconstitution Calculator

The reconstitution calculator allows you to quickly calculate the volume of a reagent to reconstitute your vial. Simply enter the mass of reagent and the target concentration and the calculator will determine the rest.

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Background: TNF-alpha

Tumor necrosis factor alpha (TNF-alpha ), also known as cachectin and TNFSF2, is the prototypic ligand of the TNF superfamily. It is a pleiotropic molecule that plays a central role in inflammation, immune system development, apoptosis, and lipid metabolism (1, 2). Mouse TNF-alpha consisits of a 35 amino acid (aa) cytoplasmic domain, a 21 aa transmembrane segment, and a 179 aa extracellular domain (ECD) (3). Within the ECD, mouse TNF-alpha shares 94% aa sequence identity with rat and 70%-77% with bovine, canine, cotton rat, equine, feline, human, porcine, rat, and rhesus TNF-alpha. TNF-alpha is produced by a wide variety of immune, epithelial, endothelial, and tumor cells (1, 2). TNF-alpha is assembled intracellularly to form a noncovalently linked homotrimer which is expressed on the cell surface (4). Cell surface TNF-alpha can induce the lysis of neighboring tumor cells and virus infected cells, and it can generate its own downstream cell signaling following ligation by soluble TNFR I (2, 5). Shedding of membrane bound TNF-alpha by TACE/ADAM17 releases the bioactive cytokine, a 55 kDa soluble trimer of the TNF-alpha extracellular domain (6-8). TNF-alpha binds the ubiquitous 55-60 kDa TNF RI (9, 10) and the hematopoietic cell-restricted 80 kDa TNF RII (11, 12), both of which are also expressed as homotrimers (1, 2, 13). Both type I and type II receptors bind TNF-alpha with comparable affinity (14), although only TNF RI contains a cytoplasmic death domain which triggers the activation of apoptosis. Soluble forms of both types of receptors are released and can neutralize the biological activity of TNF-alpha (15).

References
  1. Zelova, H. and J. Hosek (2013) Inflamm. Res. 62:641.
  2. Juhasz, K. et al. (2013) Expert Rev. Clin. Immunol. 9:335.
  3. Fransen, L. et al. (1985) Nucleic Acids Res. 13:4417.
  4. Tang, P. et al. (1996) Biochemistry 35:8216.
  5. Perez, C. et al. (1990) Cell 63:251.
  6. Black, R.A. et al. (1997) Nature 385:729.
  7. Moss, M.L. et al. (1997) Nature 385:733.
  8. Gearing, A.J.H. et al. (1994) Nature 370:555.
  9. Schall, T.J. et al. (1990) Cell 61:361.
  10. Loetscher, H. et al. (1990) Cell 61:351.
  11. Dembic, Z. et al. (1990) Cytokine 2:231.
  12. Smith, C.A. et al. (1990) Science 248:1019.
  13. Loetscher, H. et al. (1991) J. Biol. Chem. 266:18324.
  14. Pinckard, J.K. et al. (1997) J. Biol. Chem. 272:10784.
  15. Engelmann, H. et al. (1990) J. Biol. Chem. 265:1531.
Long Name
Tumor Necrosis Factor alpha
Entrez Gene IDs
7124 (Human); 21926 (Mouse); 24835 (Rat); 397086 (Porcine); 280943 (Bovine); 403922 (Canine); 100033834 (Equine); 493755 (Feline); 100009088 (Rabbit)
Alternate Names
APC1 protein; Cachectin; Cachetin; DIF; TNF; TNF, monocyte-derived; TNFA; TNF-A; TNFalpha; TNF-alpha; TNF-alphacachectin; TNFATNF, macrophage-derived; TNFG1F; TNFSF1A; TNFSF2; TNFSF2TNF superfamily, member 2; tumor necrosis factor (TNF superfamily, member 2); tumor necrosis factor alpha; Tumor necrosis factor ligand superfamily member 2; tumor necrosis factor; tumor necrosis factor-alpha

Citations for Recombinant Mouse TNF-alpha (aa 80-235) Protein

R&D Systems personnel manually curate a database that contains references using R&D Systems products. The data collected includes not only links to publications in PubMed, but also provides information about sample types, species, and experimental conditions.

201 Citations: Showing 1 - 10
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  1. DNAJB3 attenuates metabolic stress and promotes glucose uptake by eliciting Glut4 translocation
    Authors: A Arredouani, A Diane, N Khattab, I Bensmail, I Aoude, M Chikri, R Mohammad, AB Abou-Samra, M Dehbi
    Sci Rep, 2019;9(1):4772.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  2. Transcriptional suppression of CPI-17 gene expression in vascular smooth muscle cells by TNF, KLF4, and Sp1 is associated with LPS-induced vascular hypocontractility, hypotension, and mortality
    Authors: G Zhao, Y Zhong, W Su, S Liu, X Song, T Hou, X Mu, MC Gong, Z Guo
    Mol. Cell. Biol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  3. TRF2 positively regulates SULF2 expression increasing VEGF-A release and activity in tumor microenvironment
    Authors: P Zizza, R Dinami, M Porru, C Cingolani, E Salvati, A Rizzo, C D'Angelo, E Petti, CA Amoreo, M Mottolese, I Sperduti, A Chambery, R Russo, P Ostano, G Chiorino, G Blandino, A Sacconi, J Cherfils-V, C Leonetti, E Gilson, A Biroccio
    Nucleic Acids Res., 2019;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  4. Modulation of intestinal microbiota by glycyrrhizic acid prevents high-fat diet-enhanced pre-metastatic niche formation and metastasis
    Authors: M Qiu, K Huang, Y Liu, Y Yang, H Tang, X Liu, C Wang, H Chen, Y Xiong, J Zhang, J Yang
    Mucosal Immunol, 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  5. Resolution of Cutaneous Leishmaniasis and Persistence of Leishmania major in the Absence of Arginase 1
    Authors: K Paduch, A Debus, B Rai, U Schleicher, C Bogdan
    J. Immunol., 2019;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  6. Microglial activation and the nitric oxide/cGMP/PKG pathway underlie enhanced neuronal vulnerability to mitochondrial dysfunction in experimental multiple sclerosis
    Authors: A Mancini, M Tantucci, P Mazzocchet, A de Iure, V Durante, L Macchioni, C Giampà, A Alvino, L Gaetani, C Costa, A Tozzi, P Calabresi, M Di Filippo
    Neurobiol. Dis., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  7. Differentiated Macrophages Acquire a Pro-Inflammatory and Cell Death-Resistant Phenotype Due to Increasing XIAP and P38-mediated inhibition of RipK1
    Authors: D Rijal, A Ariana, A Wight, K Kim, NA Alturki, Z Aamir, E Ametepe, RG Korneluk, C Tiedje, MB Menon, M Gaestel, S McComb, S Sad
    J. Biol. Chem., 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  8. eIF4A inhibition prevents the onset of cytokine-induced muscle wasting by blocking the STAT3 and iNOS pathways
    Authors: Z Cramer, J Sadek, GG Vazquez, S Di Marco, A Pause, J Pelletier, IE Gallouzi
    Sci Rep, 2018;8(1):8414.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  9. Chemokines cooperate with TNF to provide protective anti-viral immunity and to enhance inflammation
    Authors: A Alejo, MB Ruiz-Argüe, SM Pontejo, MDM Fernández, M Saraiva, B Hernáez, A Alcamí
    Nat Commun, 2018;9(1):1790.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  10. Translational control of depression-like behavior via phosphorylation of eukaryotic translation initiation factor 4E
    Authors: A Aguilar-Va, N Haji, D De Gregori, E Matta-Cama, MJ Eslamizade, J Popic, V Sharma, R Cao, C Rummel, A Tanti, S Wiebe, N Nuñez, S Comai, R Nadon, G Luheshi, N Mechawar, G Turecki, JC Lacaille, G Gobbi, N Sonenberg
    Nat Commun, 2018;9(1):2459.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  11. Anticancer chemotherapy and radiotherapy trigger both non-cell-autonomous and cell-autonomous death
    Authors: I Martins, SQ Raza, L Voisin, H Dakhli, A Allouch, F Law, D Sabino, D De Jong, M Thoreau, E Mintet, D Dugué, M Piacentini, ML Gougeon, F Jaulin, P Bertrand, C Brenner, DM Ojcius, G Kroemer, N Modjtahedi, E Deutsch, JL Perfettini
    Cell Death Dis, 2018;9(7):716.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  12. GPR142 prompts glucagon-like Peptide-1 release from islets to improve ? cell function
    Authors: HV Lin, J Wang, J Wang, W Li, X Wang, JT Alston, MK Thomas, DA Briere, SK Syed, AM Efanov
    Mol Metab, 2018;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  13. C/EBP? drives interactions between human MAIT cells and endothelial cells that are important for extravasation
    Authors: CH Lee, HH Zhang, SP Singh, L Koo, J Kabat, H Tsang, TP Singh, JM Farber
    Elife, 2018;7(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  14. A real-time monitoring platform of myogenesis regulators using double fluorescent labeling
    Authors: E Sapoznik, G Niu, Y Zhou, PM Prim, TL Criswell, S Soker
    PLoS ONE, 2018;13(2):e0192654.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  15. Cytoglobin affects tumorigenesis and the expression of ulcerative colitis-associated genes under chemically induced colitis in mice
    Authors: M Yassin, H Kissow, B Vainer, PD Joseph, A Hay-Schmid, J Olsen, AE Pedersen
    Sci Rep, 2018;8(1):6905.
    Species: Mouse
    Sample Types: Organoids
    Applications: Bioassay
  16. The AMPK agonist 5-aminoimidazole-4-carboxamide ribonucleotide (AICAR), but not metformin, prevents inflammation-associated cachectic muscle wasting
    Authors: DT Hall, T Griss, JF Ma, BJ Sanchez, J Sadek, AMK Tremblay, S Mubaid, A Omer, RJ Ford, N Bedard, A Pause, SS Wing, S Di Marco, GR Steinberg, RG Jones, IE Gallouzi
    EMBO Mol Med, 2018;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  17. EriB targeted inhibition of microglia activity attenuates MPP+ induced DA neuron injury through the NF-?B signaling pathway
    Authors: F Dou, X Chu, B Zhang, L Liang, G Lu, J Ding, S Chen
    Mol Brain, 2018;11(1):75.
    Species: Mouse
    Sample Types: Recombinant Protein
    Applications: ELISA (Standard)
  18. NOXA1-dependent NADPH oxidase regulates redox signaling and phenotype of vascular smooth muscle cell during atherogenesis
    Authors: AE Vendrov, A Sumida, C Canugovi, A Lozhkin, T Hayami, NR Madamanchi, MS Runge
    Redox Biol, 2018;21(0):101063.
    Species: Mouse
    Sample Types:
    Applications: Bioassay
  19. Physiological culture conditions alter myotube morphology and responses to atrophy treatments: implications for in�vitro research on muscle wasting
    Authors: E Archer-Lah, C Lan, RT Jagoe
    Physiol Rep, 2018;6(12):e13726.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  20. Extracellular Vesicles from Bone Marrow-Derived Mesenchymal Stem Cells Improve Survival from Lethal Hepatic Failure in Mice
    Authors: H Haga, IK Yan, K Takahashi, A Matsuda, T Patel
    Stem Cells Transl Med, 2017;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  21. Ca2+-Dependent Regulation of NFATc1 via KCa3.1 in Inflammatory Osteoclastogenesis
    Authors: EM Grössinger, M Kang, L Bouchareyc, R Sarin, DR Haudenschi, LN Borodinsky, IE Adamopoulo
    J. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  22. Pharmacological Effect ofCaulophyllum robustumon Collagen-Induced Arthritis and Regulation of Nitric Oxide, NF-?B, and Proinflammatory Cytokines In Vivo and In Vitro
    Authors: QH Wang, SW Lv, YY Guo, JX Duan, SY Dong, QS Wang, FM Yu, H Su, HX Kuang
    Evid Based Complement Alternat Med, 2017;2017(0):8134321.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  23. TNF? drives mitochondrial stress in POMC neurons in obesity
    Authors: CX Yi, M Walter, Y Gao, S Pitra, B Legutko, S Kälin, C Layritz, C García-Các, M Bielohuby, M Bidlingmai, SC Woods, A Ghanem, KK Conzelmann, JE Stern, M Jastroch, MH Tschöp
    Nat Commun, 2017;8(0):15143.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  24. A self-sustained loop of inflammation-driven inhibition of beige adipogenesis in obesity
    Authors: KJ Chung, A Chatzigeor, M Economopou, R Garcia-Mar, VI Alexaki, I Mitroulis, M Nati, J Gebler, T Ziemssen, SE Goelz, J Phieler, JH Lim, KP Karalis, T Papayannop, M Blüher, G Hajishenga, T Chavakis
    Nat. Immunol., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  25. Therapeutic inhibition of soluble brain TNF promotes remyelination by increasing myelin phagocytosis by microglia
    Authors: M Karamita, C Barnum, W Möbius, MG Tansey, DE Szymkowski, H Lassmann, L Probert
    JCI Insight, 2017;2(8):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  26. Endothelium-derived extracellular vesicles promote splenic monocyte mobilization in myocardial infarction
    Authors: N Akbar, JE Digby, TJ Cahill, AN Tavare, AL Corbin, S Saluja, S Dawkins, L Edgar, N Rawlings, K Ziberna, E McNeill,, E Johnson, AA Aljabali, RA Dragovic, M Rohling, TG Belgard, IA Udalova, DR Greaves, KM Channon, PR Riley, DC Anthony, RP Choudhury
    JCI Insight, 2017;2(17):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  27. H3K27me3 dynamics dictate evolving uterine states in pregnancy and parturition
    Authors: P Nancy, J Siewiera, G Rizzuto, E Tagliani, I Osokine, P Manandhar, I Dolgalev, C Clementi, A Tsirigos, A Erlebacher
    J. Clin. Invest., 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  28. Possible involvement of NETosis in inflammatory processes in the eye: Evidence from a small cohort of patients
    Authors: T Barliya, R Dardik, Y Nisgav, M Dachbash, D Gaton, G Kenet, R Ehrlich, D Weinberger, T Livnat
    Mol. Vis., 2017;23(0):922-932.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  29. Endogenous TNF? orchestrates the trafficking of neutrophils into and within lymphatic vessels during acute inflammation
    Authors: S Arokiasamy, C Zakian, J Dilliway, W Wang, S Nourshargh, MB Voisin
    Sci Rep, 2017;7(0):44189.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  30. Fibroblast reticular cells engineer a blastema extracellular network during digit tip regeneration in mice
    Authors: L Marrero, J Simkin, M Sammarco, K Muneoka
    Regeneration (Oxf), 2017;4(2):69-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  31. ASK1 (MAP3K5) is transcriptionally upregulated by E2F1 in adipose tissue in obesity, molecularly defining a human dys-metabolic obese phenotype
    Authors: Y Haim, M Blüher, D Konrad, N Goldstein, N Klöting, I Harman-Boe, B Kirshtein, D Ginsberg, T Tarnovscki, Y Gepner, I Shai, A Rudich
    Mol Metab, 2017;6(7):725-736.
    Species: Human
    Sample Types: Whole Tissue
    Applications: Bioassay
  32. Formyl peptide derived lipopeptides disclose differences between the receptors in mouse and men and call the pepducin concept in question
    Authors: M Winther, A Holdfeldt, M Sundqvist, Z Rajabkhani, M Gabl, J Bylund, C Dahlgren, H Forsman
    PLoS ONE, 2017;12(9):e0185132.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  33. Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis
    Authors: H Lin, R Muramatsu, N Maedera, H Tsunematsu, M Hamaguchi, Y Koyama, M Kuroda, K Ono, M Sawada, T Yamashita
    EBioMedicine, 2017;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  34. Mesenchymal stem cells in alleviating sepsis-induced mice cardiac dysfunction via inhibition of mTORC1-p70S6K signal pathway
    Authors: W Huang, W Fan, Y Wang, D Han, X Li, S Li, C Li, B Xu, Y Huang, X Fu, F Cao
    Cell Death Discov, 2017;3(0):16097.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  35. Deficiency of PTP1B Attenuates Hypothalamic Inflammation via Activation of the JAK2-STAT3 Pathway in Microglia
    Authors: T Tsunekawa, R Banno, A Mizoguchi, M Sugiyama, T Tominaga, T Onoue, D Hagiwara, Y Ito, S Iwama, M Goto, H Suga, Y Sugimura, H Arima
    EBioMedicine, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  36. HMGB1 is upregulated in the airways in asthma and potentiates airway smooth muscle contraction via TLR4
    Authors: L Di Candia, E Gomez, E Venereau, L Chachi, D Kaur, ME Bianchi, RA Challiss, CE Brightling, RM Saunders
    J. Allergy Clin. Immunol, 2017;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  37. Role of pterostilbene in attenuating immune mediated devastation of pancreatic beta cells via Nrf2 signaling cascade
    Authors: D Sireesh, MR Ganesh, U Dhamodhara, M Sakthivadi, S Sivasubram, P Gunasekara, KM Ramkumar
    J. Nutr. Biochem, 2017;44(0):11-21.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  38. Increased mitochondrial ROS generation mediates the loss of PVAT anticontractile effect in HFD-treated obese mice
    Authors: Rafael Menezes da Costa
    Br. J. Pharmacol, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Tissue
    Applications: Bioassay
  39. Toll/Interleukin-1 Receptor Domain Derived from TcpC (TIR-TcpC) Ameliorates Experimental Autoimmune Arthritis by Down-modulating Th17 Cell Response
    Authors: Shweta Pasi
    J Biol Chem, 2016;291(23):12358-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  40. Rac GTPase Activating Protein ARHGAP25 Regulates Leukocyte Transendothelial Migration in Mice
    J Immunol, 2016;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Neutralization
  41. Type I interferons exert anti-tumor effect via reversing immunosuppression mediated by mesenchymal stromal cells
    Authors: P Shou, Q Chen, J Jiang, C Xu, J Zhang, C Zheng, M Jiang, T Velletri, W Cao, Y Huang, Q Yang, X Han, L Zhang, L Wei, AB Rabson, YE Chin, Y Wang, Y Shi
    Oncogene, 2016;0(0):.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  42. Disruption of Lipid Raft Function Increases Expression and Secretion of Monocyte Chemoattractant Protein-1 in 3T3-L1 Adipocytes
    PLoS ONE, 2016;11(12):e0169005.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  43. Replacing the Promoter of the Murine Gene Encoding P-selectin with the Human Promoter Confers Human-like Basal and Inducible Expression in Mice.
    Authors: Liu Z, Zhang N, Shao B, Panicker S, Fu J, McEver R
    J Biol Chem, 2016;291(3):1441-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  44. RIPK3 deficiency or catalytically inactive RIPK1 provides greater benefit than MLKL deficiency in mouse models of inflammation and tissue injury
    Cell Death Differ, 2016;0(0):.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  45. Pharmacokinetic and Pharmacodynamic Characterisation of an Anti-Mouse TNF Receptor 1 Domain Antibody Formatted for In Vivo Half-Life Extension.
    Authors: Goodall L, Ovecka M, Rycroft D, Friel S, Sanderson A, Mistry P, Davies M, Stoop A
    PLoS ONE, 2015;10(9):e0137065.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  46. HDAC inhibitor-mediated beta-cell protection against cytokine-induced toxicity is STAT1 Tyr701 phosphorylation independent.
    Authors: Dahllof M, Christensen D, Harving M, Wagner B, Mandrup-Poulsen T, Lundh M
    J Interferon Cytokine Res, 2015;35(1):63-70.
    Species: Rat
    Sample Types: Whole Cells
    Applications: Bioassay
  47. The role of the prostaglandin E2 receptors in vulnerability of oligodendrocyte precursor cells to death.
    Authors: Carlson N, Bellamkonda S, Schmidt L, Redd J, Huecksteadt T, Weber L, Davis E, Wood B, Maruyama T, Rose J
    J Neuroinflammation, 2015;12(0):101.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  48. Spatial proximity of homologous alleles and long noncoding RNAs regulate a switch in allelic gene expression.
    Authors: Stratigi K, Kapsetaki M, Aivaliotis M, Town T, Flavell R, Spilianakis C
    Proc Natl Acad Sci U S A, 2015;112(13):E1577-86.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  49. Mitochondria and NADPH oxidases are the major sources of TNF-alpha/cycloheximide-induced oxidative stress in murine intestinal epithelial MODE-K cells.
    Authors: Babu D, Leclercq G, Goossens V, Vanden Berghe T, Van Hamme E, Vandenabeele P, Lefebvre R
    Cell Signal, 2015;27(6):1141-58.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  50. TRIM38 Negatively Regulates TLR3/4-Mediated Innate Immune and Inflammatory Responses by Two Sequential and Distinct Mechanisms.
    Authors: Hu M, Xie X, Yang Q, Liao C, Ye W, Lin H, Shu H
    J Immunol, 2015;195(9):4415-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  51. Inhibition of Ca2+-independent phospholipase A2beta (iPLA2beta) ameliorates islet infiltration and incidence of diabetes in NOD mice.
    Authors: Bone R, Gai Y, Magrioti V, Kokotou M, Ali T, Lei X, Tse H, Kokotos G, Ramanadham S
    Diabetes, 2015;64(2):541-54.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  52. Evasion of innate cytosolic DNA sensing by a gammaherpesvirus facilitates establishment of latent infection.
    Authors: Sun C, Schattgen S, Pisitkun P, Jorgensen J, Hilterbrand A, Wang L, West J, Hansen K, Horan K, Jakobsen M, O'Hare P, Adler H, Sun R, Ploegh H, Damania B, Upton J, Fitzgerald K, Paludan S
    J Immunol, 2015;194(4):1819-31.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  53. ZnT2 is a critical mediator of lysosomal-mediated cell death during early mammary gland involution.
    Authors: Hennigar S, Seo Y, Sharma S, Soybel D, Kelleher S
    Sci Rep, 2015;5(0):8033.
    Species: Mouse
    Sample Types: Whole Organism
    Applications: In vivo
  54. The generation of neutrophils in the bone marrow is controlled by autophagy.
    Authors: Rozman S, Yousefi S, Oberson K, Kaufmann T, Benarafa C, Simon H
    Cell Death Differ, 2015;22(3):445-56.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  55. Effector T Cell Egress via Afferent Lymph Modulates Local Tissue Inflammation.
    Authors: Gomez D, Diehl M, Crosby E, Weinkopff T, Debes G
    J Immunol, 2015;195(8):3531-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  56. Syndecan-1 in the mouse parietal peritoneum microcirculation in inflammation.
    Authors: Kowalewska P, Patrick A, Fox-Robichaud A
    PLoS ONE, 2014;9(9):e104537.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  57. Galectin-9 protein is up-regulated in astrocytes by tumor necrosis factor and promotes encephalitogenic T-cell apoptosis.
    Authors: Steelman A, Smith R, Welsh C, Li J
    J Biol Chem, 2014;288(33):23776-87.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  58. Development of a primary mouse intestinal epithelial cell monolayer culture system to evaluate factors that modulate IgA transcytosis.
    Authors: Moon C, VanDussen K, Miyoshi H, Stappenbeck T
    Mucosal Immunol, 2014;7(4):818-28.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  59. TNF-mediated damage to glomerular endothelium is an important determinant of acute kidney injury in sepsis.
    Authors: Xu C, Chang A, Hack B, Eadon M, Alper S, Cunningham P
    Kidney Int, 2014;85(1):72-81.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  60. Polymicrobial sepsis alters antigen-dependent and -independent memory CD8 T cell functions.
    Authors: Duong S, Condotta S, Rai D, Martin M, Griffith T, Badovinac V
    J Immunol, 2014;192(8):3618-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  61. Is SIRT2 required for necroptosis?
    Authors: Newton K, Hildebrand J, Shen Z, Rodriguez D, Alvarez-Diaz S, Petersen S, Shah S, Dugger D, Huang C, Auwerx J, Vandenabeele P, Green D, Ashkenazi A, Dixit V, Kaiser W, Strasser A, Degterev A, Silke J
    Nature, 2014;506(7489):E4-6.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In vivo
  62. Type-I interferon signaling through ISGF3 complex is required for sustained Rip3 activation and necroptosis in macrophages.
    Authors: McComb S, Cessford E, Alturki N, Joseph J, Shutinoski B, Startek J, Gamero A, Mossman K, Sad S
    Proc Natl Acad Sci U S A, 2014;111(31):E3206-13.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  63. The RhoGAP activity of myosin IXB is critical for osteoclast podosome patterning, motility, and resorptive capacity.
    Authors: McMichael B, Scherer K, Franklin N, Lee B
    PLoS ONE, 2014;9(1):e87402.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  64. Endothelial cell-derived chemerin promotes dendritic cell transmigration.
    Authors: Gonzalvo-Feo S, Del Prete A, Pruenster M, Salvi V, Wang L, Sironi M, Bierschenk S, Sperandio M, Vecchi A, Sozzani S
    J Immunol, 2014;192(5):2366-73.
  65. Matrix metalloproteinase-9 deficiency attenuates diabetic nephropathy by modulation of podocyte functions and dedifferentiation.
    Authors: Li S, Huang P, Yang A, Tarng D, Yang W, Lin C, Chen J, Schmid-Schonbein G, Lin S
    Kidney Int, 2014;86(2):358-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  66. IFN-gamma or IFN-alpha ameliorates chronic proliferative dermatitis by inducing expression of linear ubiquitin chain assembly complex.
    Authors: Tamiya H, Terao M, Takiuchi T, Nakahara M, Sasaki Y, Katayama I, Yoshikawa H, Iwai K
    J Immunol, 2014;192(8):3793-804.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  67. Porphyromonas gingivalis-derived lysine gingipain enhances osteoclast differentiation induced by tumor necrosis factor-alpha and interleukin-1beta but suppresses that by interleukin-17A: importance of proteolytic degradation of osteoprotegerin by lysine gingipain.
    Authors: Akiyama T, Miyamoto Y, Yoshimura K, Yamada A, Takami M, Suzawa T, Hoshino M, Imamura T, Akiyama C, Yasuhara R, Mishima K, Maruyama T, Kohda C, Tanaka K, Potempa J, Yasuda H, Baba K, Kamijo R
    J Biol Chem, 2014;289(22):15621-30.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  68. The cytokine midkine supports neutrophil trafficking during acute inflammation by promoting adhesion via beta2 integrins (CD11/CD18).
    Authors: Weckbach L, Gola A, Winkelmann M, Jakob S, Groesser L, Borgolte J, Pogoda F, Pick R, Pruenster M, Muller-Hocker J, Deindl E, Sperandio M, Walzog B
    Blood, 2014;123(12):1887-96.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  69. Pseudomonas aeruginosa quorum-sensing molecule homoserine lactone modulates inflammatory signaling through PERK and eI-F2alpha.
    Authors: Grabiner M, Fu Z, Wu T, Barry K, Schwarzer C, Machen T
    J Immunol, 2014;193(3):1459-67.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  70. Inhibition of keratinocyte differentiation by the synergistic effect of IL-17A, IL-22, IL-1alpha, TNFalpha and oncostatin M.
    Authors: Rabeony H, Petit-Paris I, Garnier J, Barrault C, Pedretti N, Guilloteau K, Jegou J, Guillet G, Huguier V, Lecron J, Bernard F, Morel F
    PLoS ONE, 2014;9(7):e101937.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  71. Unbiased expression mapping identifies a link between the complement and cholinergic systems in the rat central nervous system.
    Authors: Lindblom R, Strom M, Heinig M, Al Nimer F, Aeinehband S, Berg A, Dominguez C, Vijayaraghavan S, Zhang X, Harnesk K, Zelano J, Hubner N, Cullheim S, Darreh-Shori T, Diez M, Piehl F
    J Immunol, 2014;192(3):1138-53.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  72. Toxoplasma gondii virulence factor ROP18 inhibits the host NF-kappaB pathway by promoting p65 degradation.
    Authors: Du J, An R, Chen L, Shen Y, Chen Y, Cheng L, Jiang Z, Zhang A, Yu L, Chu D, Shen Y, Luo Q, Chen H, Wan L, Li M, Xu X, Shen J
    J Biol Chem, 2014;289(18):12578-92.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  73. NRROS negatively regulates reactive oxygen species during host defence and autoimmunity.
    Authors: Noubade, Rajkumar, Wong, Kit, Ota, Naruhisa, Rutz, Sascha, Eidenschenk, Celine, Valdez, Patricia, Ding, Jiabing, Peng, Ivan, Sebrell, Andrew, Caplazi, Patrick, DeVoss, Jason, Soriano, Robert H, Sai, Tao, Lu, Rongze, Modrusan, Zora, Hackney, Jason, Ouyang, Wenjun
    Nature, 2014;509(7499):235-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  74. TGFbeta-mediated suppression of CD248 in non-cancer cells via canonical Smad-dependent signaling pathways is uncoupled in cancer cells.
    Authors: Suresh Babu S, Valdez Y, Xu A, O'Byrne A, Calvo F, Lei V, Conway E
    BMC Cancer, 2014;14(0):113.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  75. Lack of host gut microbiota alters immune responses and intestinal granuloma formation during schistosomiasis.
    Authors: Holzscheiter M, Layland L, Loffredo-Verde E, Mair K, Vogelmann R, Langer R, Wagner H, Prazeres da Costa C
    Clin Exp Immunol, 2014;175(2):246-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  76. Reversal of beta cell de-differentiation by a small molecule inhibitor of the TGFbeta pathway.
    Authors: Blum B, Roose A, Barrandon O, Maehr R, Arvanites A, Davidow L, Davis J, Peterson Q, Rubin L, Melton D
    Elife, 2014;3(0):e02809.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  77. Free fatty acids and IL-6 induce adipocyte galectin-3 which is increased in white and brown adipose tissues of obese mice.
    Authors: Krautbauer S, Eisinger K, Hader Y, Buechler C
    Cytokine, 2014;69(2):263-71.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  78. PKM2 regulates the Warburg effect and promotes HMGB1 release in sepsis.
    Authors: Yang L, Xie M, Yang M, Yu Y, Zhu S, Hou W, Kang R, Lotze M, Billiar T, Wang H, Cao L, Tang D
    Nat Commun, 2014;5(0):4436.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  79. Caspase-cleaved arrestin-2 and BID cooperatively facilitate cytochrome C release and cell death.
    Authors: Kook, S, Zhan, X, Cleghorn, W M, Benovic, J L, Gurevich, V V, Gurevich, E V
    Cell Death Differ, 2014;21(1):172-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  80. Oncostatin M acting via OSMR, augments the actions of IL-1 and TNF in synovial fibroblasts.
    Authors: Le Goff B, Singbrant S, Tonkin B, Martin T, Romas E, Sims N, Walsh N
    Cytokine, 2014;68(2):101-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  81. Technical advance: monitoring the trafficking of neutrophil granulocytes and monocytes during the course of tissue inflammation by noninvasive 19F MRI.
    Authors: Temme S, Jacoby C, Ding Z, Bonner F, Borg N, Schrader J, Flogel U
    J Leukoc Biol, 2014;95(4):689-97.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  82. Netrin-1 promotes adipose tissue macrophage retention and insulin resistance in obesity.
    Authors: Ramkhelawon B, Hennessy E, Menager M, Ray T, Sheedy F, Hutchison S, Wanschel A, Oldebeken S, Geoffrion M, Spiro W, Miller G, McPherson R, Rayner K, Moore K
    Nat Med, 2014;20(4):377-84.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  83. Transforming growth factor beta-activated kinase 1 signaling pathway critically regulates myocardial survival and remodeling.
    Authors: Li L, Chen Y, Doan J, Murray J, Molkentin J, Liu Q
    Circulation, 2014;130(24):2162-72.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  84. TGF-beta promotes immune responses in the presence of mesenchymal stem cells.
    Authors: Xu C, Yu P, Han X, DU L, Gan J, Wang Y, Shi Y
    J Immunol, 2014;192(1):103-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  85. A pseudopterane diterpene isolated from the octocoral Pseudopterogorgia acerosa inhibits the inflammatory response mediated by TLR-ligands and TNF-alpha in macrophages.
    Authors: Gonzalez Y, Doens D, Santamaria R, Ramos M, Restrepo C, Barros de Arruda L, Lleonart R, Gutierrez M, Fernandez P
    PLoS ONE, 2013;8(12):e84107.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  86. Enhancement of inflammatory protein expression and nuclear factor Kappab (NF-Kappab) activity by trichostatin A (TSA) in OP9 preadipocytes.
    Authors: Sato T, Kotake D, Hiratsuka M, Hirasawa N
    PLoS ONE, 2013;8(3):e59702.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  87. Skeletal muscle cells express ICAM-1 after muscle overload and ICAM-1 contributes to the ensuing hypertrophic response.
    Authors: Dearth C, Goh Q, Marino J, Cicinelli P, Torres-Palsa M, Pierre P, Worth R, Pizza F
    PLoS ONE, 2013;8(3):e58486.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  88. Decorin potentiates interferon-gamma activity in a model of allergic inflammation.
    Authors: Bocian C, Urbanowitz A, Owens R, Iozzo R, Gotte M, Seidler D
    J Biol Chem, 2013;288(18):12699-711.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  89. Monocyte chemoattractant protein-1/CCL2 produced by stromal cells promotes lung metastasis of 4T1 murine breast cancer cells.
    Authors: Yoshimura T, Howard O, Ito T, Kuwabara M, Matsukawa A, Chen K, Liu Y, Liu M, Oppenheim J, Wang J
    PLoS ONE, 2013;8(3):e58791.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  90. IL-1beta promotes antimicrobial immunity in macrophages by regulating TNFR signaling and caspase-3 activation.
    Authors: Jayaraman P, Sada-Ovalle I, Nishimura T, Anderson A, Kuchroo V, Remold H, Behar S
    J Immunol, 2013;190(8):4196-204.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  91. Ezrin-radixin-moesin-binding phosphoprotein 50 (EBP50) and nuclear factor-kappaB (NF-kappaB): a feed-forward loop for systemic and vascular inflammation.
    Authors: Leslie K, Song G, Barrick S, Wehbi V, Vilardaga J, Bauer P, Bisello A
    J Biol Chem, 2013;288(51):36426-36.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  92. Optineurin insufficiency impairs IRF3 but not NF-kappaB activation in immune cells.
    Authors: Munitic I, Giardino Torchia M, Meena N, Zhu G, Li C, Ashwell J
    J Immunol, 2013;191(12):6231-40.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Cell Culture
  93. Suppression of inflammation and acute lung injury by Miz1 via repression of C/EBP-delta.
    Authors: Do-Umehara H, Chen C, Urich D, Zhou L, Qiu J, Jang S, Zander A, Baker M, Eilers M, Sporn P, Ridge K, Sznajder J, Budinger G, Mutlu G, Lin A, Liu J
    Nat Immunol, 2013;14(5):461-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  94. IL-33 causes selective mast cell tolerance to bacterial cell wall products by inducing IRAK1 degradation.
    Authors: Sandig H, Jobbings C, Roldan N, Whittingham-Dowd J, Orinska Z, Takeuchi O, Akira S, Bulfone-Paus S
    Eur J Immunol, 2013;43(4):979-88.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  95. Host-derived MCP-1 and MIP-1alpha regulate protective anti-tumor immunity to localized and metastatic B16 melanoma.
    Authors: Nakasone Y, Fujimoto M, Matsushita T, Hamaguchi Y, Huu DL, Yanaba M, Sato S, Takehara K, Hasegawa M
    Am. J. Pathol., 2012;180(1):365-74.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  96. Pericytes support neutrophil subendothelial cell crawling and breaching of venular walls in vivo.
    Authors: Proebstl D, Voisin MB, Woodfin A, Whiteford J, D'Acquisto F, Jones GE, Rowe D, Nourshargh S
    J. Exp. Med., 2012;209(6):1219-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  97. Hepatocyte-specific mutation of both NF-kappaB RelA and STAT3 abrogates the acute phase response in mice.
    Authors: Quinton LJ, Blahna MT, Jones MR, Allen E, Ferrari JD, Hilliard KL, Zhang X, Sabharwal V, Algul H, Akira S, Schmid RM, Pelton SI, Spira A, Mizgerd JP
    J. Clin. Invest., 2012;122(5):1758-63.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  98. Hepatocarcinogenesis in FXR-/- mice mimics human HCC progression that operates through HNF1alpha regulation of FXR expression.
    Authors: Liu N, Meng Z, Lou G, Zhou W, Wang X, Zhang Y, Zhang L, Liu X, Yen Y, Lai L, Forman BM, Xu Z, Xu R, Huang W
    Mol. Endocrinol., 2012;26(5):775-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  99. Matrix metalloprotease 9 mediates neutrophil migration into the airways in response to influenza virus-induced toll-like receptor signaling.
    Authors: Bradley LM, Douglass MF, Chatterjee D, Akira S, Baaten BJ
    PLoS Pathog., 2012;8(4):e1002641.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  100. Eukaryotic initiation factor 2 (eIF2) signaling regulates proinflammatory cytokine expression and bacterial invasion.
    Authors: Shrestha N, Bahnan W, Wiley D, Barber G, Fields K, Schesser K
    J Biol Chem, 2012;287(34):28738-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  101. The role of alveolar epithelial cells in initiating and shaping pulmonary immune responses: communication between innate and adaptive immune systems.
    Authors: Chuquimia OD, Petursdottir DH, Rahman MJ, Hartl K, Singh M, Fernandez C
    PLoS ONE, 2012;7(2):e32125.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  102. Regulation of innate CD8+ T-cell activation mediated by cytokines.
    Proc Natl Acad Sci U S A, 2012;109(25):9971-6.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  103. TNFR2 interposes the proliferative and NF-kappaB-mediated inflammatory response by podocytes to TNF-alpha.
    Authors: Bruggeman LA, Drawz PE, Kahoud N, Lin K, Barisoni L, Nelson PJ
    Lab. Invest., 2011;91(3):413-25.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  104. IL-22 Is Produced by Innate Lymphoid Cells and Limits Inflammation in Allergic Airway Disease.
    Authors: Taube C, Tertilt C, Gyulveszi G, Dehzad N, Kreymborg K, Schneeweiss K, Michel E, Reuter S, Renauld JC, Arnold-Schild D, Schild H, Buhl R, Becher B
    PLoS ONE, 2011;6(7):e21799.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  105. LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism.
    Authors: Tiller G, Laumen H, Fischer-Posovszky P, Finck A, Skurk T, Keuper M, Brinkmann U, Wabitsch M, Link D, Hauner H
    Int J Obes (Lond), 2011;35(2):208-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  106. Endothelial LSP1 is involved in endothelial dome formation, minimizing vascular permeability changes during neutrophil transmigration in vivo.
    Authors: Petri B, Kaur J, Long EM, Li H, Parsons SA, Butz S, Phillipson M, Vestweber D, Patel KD, Robbins SM, Kubes P
    Blood, 2011;117(3):942-52.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  107. The encephalitogenicity of T(H)17 cells is dependent on IL-1- and IL-23-induced production of the cytokine GM-CSF.
    Authors: El-Behi M, Ciric B, Dai H
    Nat. Immunol., 2011;12(6):568-75.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  108. IL-17A and TNF-alpha Exert Synergistic Effects on Expression of CXCL5 by Alveolar Type II Cells In Vivo and In Vitro.
    Authors: Liu Y, Mei J, Gonzales L, Yang G, Dai N, Wang P, Zhang P, Favara M, Malcolm KC, Guttentag S, Worthen GS
    J. Immunol., 2011;186(5):3197-205.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  109. Direct bone formation during distraction osteogenesis does not require TNFalpha receptors and elevated serum TNFalpha fails to inhibit bone formation in TNFR1 deficient mice.
    Authors: Wahl EC, Aronson J, Liu L, Skinner RA, Miller MJ, Cockrell GE, Fowlkes JL, Thrailkill KM, Bunn RC, Ronis MJ, Lumpkin CK
    Bone, 2010;46(2):410-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  110. ProNGF induces TNFalpha-dependent death of retinal ganglion cells through a p75NTR non-cell-autonomous signaling pathway.
    Authors: Lebrun-Julien F, Bertrand MJ, De Backer O, Stellwagen D, Morales CR, Di Polo A, Barker PA
    Proc. Natl. Acad. Sci. U.S.A., 2010;107(8):3817-22.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  111. Vitamin D3 upregulated protein 1 suppresses TNF-alpha-induced NF-kappaB activation in hepatocarcinogenesis.
    Authors: Kwon HJ, Won YS, Suh HW, Jeon JH, Shao Y, Yoon SR, Chung JW, Kim TD, Kim HM, Nam KH, Yoon WK, Kim DG, Kim JH, Kim YS, Kim DY, Kim HC, Choi I
    J. Immunol., 2010;185(7):3980-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  112. A novel role for constitutively expressed epithelial-derived chemokines as antibacterial peptides in the intestinal mucosa.
    Authors: Kotarsky K, Sitnik KM, Stenstad H, Kotarsky H, Schmidtchen A, Koslowski M, Wehkamp J, Agace WW
    Mucosal Immunol, 2010;3(1):40-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  113. Tumor necrosis factor-alpha regulates distinct molecular pathways and gene networks in cultured skeletal muscle cells.
    Authors: Bhatnagar S, Panguluri SK, Gupta SK, Dahiya S, Lundy RF, Kumar A
    PLoS ONE, 2010;5(10):e13262.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  114. ADAM17 is regulated by a rapid and reversible mechanism that controls access to its catalytic site.
    Authors: Le Gall SM, Maretzky T, Issuree PD, Niu XD, Reiss K, Saftig P, Khokha R, Lundell D, Blobel CP
    J. Cell. Sci., 2010;123(0):3913-22.
    Species: Mouse
    Sample Types:
    Applications: ELISA (Standard)
  115. Tyrosine kinase Btk regulates E-selectin-mediated integrin activation and neutrophil recruitment by controlling phospholipase C (PLC) gamma2 and PI3Kgamma pathways.
    Authors: Mueller H, Stadtmann A, Van Aken H, Hirsch E, Wang D, Ley K, Zarbock A
    Blood, 2010;115(15):3118-27.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  116. Epifluorescence intravital microscopy of murine corneal dendritic cells.
    Authors: Lee EJ, Rosenbaum JT, Planck SR
    Invest. Ophthalmol. Vis. Sci., 2010;51(4):2101-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  117. IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.
    Authors: Blumberg H, Dinh H, Dean C, Trueblood ES, Bailey K, Shows D, Bhagavathula N, Aslam MN, Varani J, Towne JE, Sims JE
    J. Immunol., 2010;185(7):4354-62.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  118. Lipid-cytokine-chemokine cascade drives neutrophil recruitment in a murine model of inflammatory arthritis.
    Authors: Chou RC, Kim ND, Sadik CD
    Immunity, 2010;33(2):266-78.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  119. Loss of CD34 leads to exacerbated autoimmune arthritis through increased vascular permeability.
    Authors: Blanchet MR, Gold M, Maltby S, Bennett J, Petri B, Kubes P, Lee DM, McNagny KM
    J. Immunol., 2010;184(3):1292-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  120. Ectodomain shedding of EGFR ligands and TNFR1 dictates hepatocyte apoptosis during fulminant hepatitis in mice.
    Authors: Murthy A, Defamie V, Smookler DS
    J. Clin. Invest., 2010;120(8):2731-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  121. CD99 and CD99L2 act at the same site as, but independently of, PECAM-1 during leukocyte diapedesis.
    Authors: Bixel MG, Li H, Petri B, Khandoga AG, Khandoga A, Zarbock A, Wolburg-Buchholz K, Wolburg H, Sorokin L, Zeuschner D, Maerz S, Butz S, Krombach F, Vestweber D
    Blood, 2010;116(7):1172-84.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  122. Skin Inflammation Induced by the Synergistic Action of IL-17A, IL-22, Oncostatin M, IL-1alpha, and TNF-alpha Recapitulates Some Features of Psoriasis.
    Authors: Guilloteau K, Paris I, Pedretti N, Boniface K, Juchaux F, Huguier V, Guillet G, Bernard FX, Lecron JC, Morel F
    J. Immunol., 2010;184(0):5263-70.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  123. RAGE and ICAM-1 cooperate in mediating leukocyte recruitment during acute inflammation in vivo.
    Authors: Frommhold D, Kamphues A, Hepper I, Pruenster M, Lukic IK, Socher I, Zablotskaya V, Buschmann K, Lange-Sperandio B, Schymeinsky J, Ryschich E, Poeschl J, Kupatt C, Nawroth PP, Moser M, Walzog B, Bierhaus A, Sperandio M
    Blood, 2010;116(5):841-9.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  124. The sensing of environmental stimuli by follicular dendritic cells promotes immunoglobulin A generation in the gut.
    Authors: Suzuki K, Maruya M, Kawamoto S
    Immunity, 2010;33(1):71-83.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  125. ST2 deficient mice display a normal host defense against pulmonary infection with Mycobacterium tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Florquin S, McKenzie AN, van der Poll T
    Microbes Infect., 2009;11(4):524-30.
  126. Fra-1/AP-1 impairs inflammatory responses and chondrogenesis in fracture healing.
    Authors: Yamaguchi T, Takada Y, Maruyama K, Shimoda K, Arai Y, Nango N, Kosaki N, Takaishi H, Toyama Y, Matsuo K
    J. Bone Miner. Res., 2009;24(12):2056-65.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  127. TNF superfamily member, TL1A, is a potential mucosal vaccine adjuvant.
    Authors: Kayamuro H, Yoshioka Y, Abe Y, Katayama K, Yoshida T, Yamashita K, Yoshikawa T, Hiroi T, Itoh N, Kawai Y, Mayumi T, Kamada H, Tsunoda S, Tsutsumi Y
    Biochem. Biophys. Res. Commun., 2009;384(3):296-300.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  128. A TLR2 agonist in German cockroach frass activates MMP-9 release and is protective against allergic inflammation in mice.
    Authors: Page K, Ledford JR, Zhou P, Wills-Karp M
    J. Immunol., 2009;183(5):3400-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  129. Functional characterization of IL-17F as a selective neutrophil attractant in psoriasis.
    Authors: Watanabe H, Kawaguchi M, Fujishima S, Ogura M, Matsukura S, Takeuchi H, Ohba M, Sueki H, Kokubu F, Hizawa N, Adachi M, Huang SK, Iijima M
    J. Invest. Dermatol., 2009;129(3):650-6.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  130. Primed CD8(+) T-cell responses to allogeneic endothelial cells are controlled by local complement activation.
    Authors: Raedler H, Yang M, Lalli PN
    Am. J. Transplant., 2009;9(8):1784-95.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  131. The induction of antibody production by IL-6 is indirectly mediated by IL-21 produced by CD4+ T cells.
    Authors: Dienz O, Eaton SM, Bond JP, Neveu W, Moquin D, Noubade R, Briso EM, Charland C, Leonard WJ, Ciliberto G, Teuscher C, Haynes L, Rincon M
    J. Exp. Med., 2009;206(1):69-78.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  132. Induction of hepatitis by JNK-mediated expression of TNF-alpha.
    Authors: Das M, Sabio G, Jiang F, Rincon M, Flavell RA, Davis RJ
    Cell, 2009;136(2):249-60.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  133. A lymphotoxin-driven pathway to hepatocellular carcinoma.
    Authors: Haybaeck J, Zeller N, Wolf MJ, Weber A, Wagner U, Kurrer MO, Bremer J, Iezzi G, Graf R, Clavien PA, Thimme R, Blum H, Nedospasov SA, Zatloukal K, Ramzan M, Ciesek S, Pietschmann T, Marche PN, Karin M, Kopf M, Browning JL, Aguzzi A, Heikenwalder M
    Cancer Cell, 2009;16(4):295-308.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  134. Kindlin-3 is required for beta2 integrin-mediated leukocyte adhesion to endothelial cells.
    Authors: Moser M, Bauer M, Schmid S, Ruppert R, Schmidt S, Sixt M, Wang HV, Sperandio M, Fassler R
    Nat. Med., 2009;15(3):300-5.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  135. Thymic regulation of autoimmune disease by accelerated differentiation of Foxp3+ regulatory T cells through IL-7 signaling pathway.
    Authors: Chen X, Fang L, Song S, Guo TB, Liu A, Zhang JZ
    J. Immunol., 2009;183(10):6135-44.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  136. Activation of the NLRP3 inflammasome in dendritic cells induces IL-1beta-dependent adaptive immunity against tumors.
    Authors: Ghiringhelli F, Apetoh L, Tesniere A, Aymeric L, Ma Y, Ortiz C, Vermaelen K, Panaretakis T, Mignot G, Ullrich E, Perfettini JL, Schlemmer F, Tasdemir E, Uhl M, Genin P, Civas A, Ryffel B, Kanellopoulos J, Tschopp J, Andre F, Lidereau R, McLaughlin NM, Haynes NM, Smyth MJ, Kroemer G, Zitvogel L
    Nat. Med., 2009;15(10):1170-8.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  137. Heterotypic interactions enabled by polarized neutrophil microdomains mediate thromboinflammatory injury.
    Authors: Hidalgo A, Chang J, Jang JE, Peired AJ, Chiang EY, Frenette PS
    Nat. Med., 2009;15(4):384-91.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  138. Exogenous stromal cell-derived factor-1 induces modest leukocyte recruitment in vivo.
    Authors: Kerfoot SM, Andonegui G, Bonder CS, Liu L
    Am. J. Physiol. Heart Circ. Physiol., 2008;294(6):H2524-34.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  139. Leukocyte trafficking in a mouse model for leukocyte adhesion deficiency II/congenital disorder of glycosylation IIc.
    Authors: Yakubenia S, Frommhold D, Scholch D, Hellbusch CC, Korner C, Petri B, Jones C, Ipe U, Bixel MG, Krempien R, Sperandio M, Wild MK
    Blood, 2008;112(4):1472-81.
    Species: Mouse
    Sample Types: In Vivo
    Applications: Bioassay
  140. XIAP regulates intracellular ROS by enhancing antioxidant gene expression.
    Authors: Resch U, Schichl YM, Sattler S, de Martin R
    Biochem. Biophys. Res. Commun., 2008;375(1):156-61.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  141. CD14 contributes to pulmonary inflammation and mortality during murine tuberculosis.
    Authors: Wieland CW, van der Windt GJ, Wiersinga WJ, Florquin S, van der Poll T
    Immunology, 2008;125(2):272-9.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  142. Tumor necrosis factor-alpha and endothelial cells modulate Notch signaling in the bone marrow microenvironment during inflammation.
    Authors: Fernandez L, Rodriguez S, Huang H, Chora A, Fernandes J, Mumaw C, Cruz E, Pollok K, Cristina F, Price JE, Ferkowicz MJ, Scadden DT, Clauss M, Cardoso AA, Carlesso N
    Exp. Hematol., 2008;36(5):545-558.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  143. Insulin-like growth factor-1 improves survival in sepsis via enhanced hepatic bacterial clearance.
    Authors: Ashare A, Nymon AB, Doerschug KC, Morrison JM, Monick MM, Hunninghake GW
    Am. J. Respir. Crit. Care Med., 2008;178(2):149-57.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  144. A contrast agent recognizing activated platelets reveals murine cerebral malaria pathology undetectable by conventional MRI.
    Authors: von Zur Muhlen C, Sibson NR, Peter K, Campbell SJ, Wilainam P, Grau GE, Bode C, Choudhury RP, Anthony DC
    J. Clin. Invest., 2008;118(3):1198-207.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  145. Rod-Shaped monocytes patrol the brain vasculature and give rise to perivascular macrophages under the influence of proinflammatory cytokines and angiopoietin-2.
    Authors: Audoy-Remus J, Richard JF, Soulet D, Zhou H, Kubes P, Vallieres L
    J. Neurosci., 2008;28(41):10187-99.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  146. Interferon-gamma limits Th1 lymphocyte adhesion to inflamed endothelium: a nitric oxide regulatory feedback mechanism.
    Authors: Norman MU, Zbytnuik L, Kubes P
    Eur. J. Immunol., 2008;38(5):1368-80.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  147. TNF receptor independent activation of the cytomegalovirus major immediate early enhancer in response to transplantation.
    Authors: Zhang Z, Kim SJ, Varghese T, Thomas G, Hummel M, Abecassis M
    Transplantation, 2008;85(7):1039-45.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  148. The role of lipocalin 2 in the regulation of inflammation in adipocytes and macrophages.
    Authors: Zhang J, Wu Y, Zhang Y, LeRoith D, Bernlohr DA, Chen X
    Mol. Endocrinol., 2008;22(6):1416-26.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  149. Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.
    Authors: Mahoney DJ, Cheung HH, Mrad RL, Plenchette S, Simard C, Enwere E, Arora V, Mak TW, LaCasse EC, Waring J, Korneluk RG
    Proc. Natl. Acad. Sci. U.S.A., 2008;105(33):11778-83.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  150. An L-selectin ligand distinct from P-selectin glycoprotein ligand-1 is expressed on endothelial cells and promotes neutrophil rolling in inflammation.
    Authors: Shigeta A, Matsumoto M, Tedder TF, Lowe JB, Miyasaka M, Hirata T
    Blood, 2008;112(13):4915-23.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  151. A potential role of thymic stromal lymphopoietin in the recruitment of macrophages to mouse intervertebral disc cells via monocyte chemotactic protein 1 induction: implications for herniated discs.
    Authors: Ohba T, Haro H, Ando T, Koyama K, Hatsushika K, Suenaga F, Ohnuma Y, Nakamura Y, Katoh R, Ogawa H, Hamada Y, Nakao A
    Arthritis Rheum., 2008;58(11):3510-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  152. PSGL-1 engagement by E-selectin signals through Src kinase Fgr and ITAM adapters DAP12 and FcR gamma to induce slow leukocyte rolling.
    Authors: Zarbock A, Abram CL, Hundt M, Altman A, Lowell CA, Ley K
    J. Exp. Med., 2008;205(10):2339-47.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  153. Bv8 regulates myeloid-cell-dependent tumour angiogenesis.
    Authors: Shojaei F, Wu X, Zhong C, Yu L, Liang XH, Yao J, Blanchard D, Bais C, Peale FV, van Bruggen N, Ho C, Ross J, Tan M, Carano RA, Meng YG, Ferrara N
    Nature, 2007;450(7171):825-31.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  154. Gas6 promotes inflammation by enhancing interactions between endothelial cells, platelets, and leukocytes.
    Authors: Tjwa M, Bellido-Martin L, Lin Y, Lutgens E, Plaisance S, Bono F, Delesque-Touchard N, Herve C, Moura R, Billiau AD, Aparicio C, Levi M, Daemen M, Dewerchin M, Lupu F, Arnout J, Herbert JM, Waer M, Garcia de Frutos P, Dahlback B, Carmeliet P, Hoylaerts MF, Moons L
    Blood, 2007;111(8):4096-105.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  155. Dickkopf-1 is a master regulator of joint remodeling.
    Authors: Diarra D, Stolina M, Polzer K, Zwerina J, Ominsky MS, Dwyer D, Korb A, Smolen J, Hoffmann M, Scheinecker C, van der Heide D, Landewe R, Lacey D, Richards WG, Schett G
    Nat. Med., 2007;13(2):156-63.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  156. TNF-related weak inducer of apoptosis (TWEAK) is a potent skeletal muscle-wasting cytokine.
    Authors: Dogra C, Changotra H, Wedhas N, Qin X, Wergedal JE, Kumar A
    FASEB J., 2007;21(8):1857-69.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  157. Interleukin 10 regulates inflammatory cytokine synthesis to protect against lipopolysaccharide-induced abortion and fetal growth restriction in mice.
    Authors: Robertson SA, Care AS, Skinner RJ
    Biol. Reprod., 2007;76(5):738-48.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  158. IL-18 is a key proximal mediator of contact hypersensitivity and allergen-induced Langerhans cell migration in murine epidermis.
    Authors: Antonopoulos C, Cumberbatch M, Mee JB, Dearman RJ, Wei XQ, Liew FY, Kimber I, Groves RW
    J. Leukoc. Biol., 2007;83(2):361-7.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  159. Pivotal advance: inhibition of HMGB1 nuclear translocation as a mechanism for the anti-rheumatic effects of gold sodium thiomalate.
    Authors: Zetterstrom CK, Jiang W, Wahamaa H, Ostberg T, Aveberger AC, Schierbeck H, Lotze MT, Andersson U, Pisetsky DS, Erlandsson Harris H
    J. Leukoc. Biol., 2007;83(1):31-8.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  160. Leukocyte PI3Kgamma and PI3Kdelta have temporally distinct roles for leukocyte recruitment in vivo.
    Authors: Liu L, Puri KD, Penninger JM, Kubes P
    Blood, 2007;110(4):1191-8.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  161. Dominant-negative inhibitors of soluble TNF attenuate experimental arthritis without suppressing innate immunity to infection.
    Authors: Zalevsky J, Secher T, Ezhevsky SA, Janot L, Steed PM, O'Brien C, Eivazi A, Kung J, Nguyen DH, Doberstein SK, Erard F, Ryffel B, Szymkowski DE
    J. Immunol., 2007;179(3):1872-83.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  162. Endothelial NOS is required for SDF-1alpha/CXCR4-mediated peripheral endothelial adhesion of c-kit+ bone marrow stem cells.
    Authors: Kaminski A, Ma N, Donndorf P, Lindenblatt N, Feldmeier G, Ong LL, Furlani D, Skrabal CA, Liebold A, Vollmar B, Steinhoff G
    Lab. Invest., 2007;88(1):58-69.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  163. Role of interleukin-1beta and tumor necrosis factor-alpha-dependent expression of cyclooxygenase-2 mRNA in thermal hyperalgesia induced by chronic inflammation in mice.
    Authors: Narita M, Shimamura M, Imai S, Kubota C, Yajima Y, Takagi T, Shiokawa M, Inoue T, Suzuki M, Suzuki T
    Neuroscience, 2007;152(2):477-86.
  164. Interferon-gamma synergises with tumour necrosis factor and lymphotoxin-alpha to enhance the mRNA and protein expression of adhesion molecules in mouse brain endothelial cells.
    Authors: Weiser S, Miu J, Ball HJ, Hunt NH
    Cytokine, 2007;37(1):84-91.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  165. Oncostatin M enhances CCL21 expression by microvascular endothelial cells and increases the efficiency of dendritic cell trafficking to lymph nodes.
    Authors: Sugaya M, Fang L, Cardones AR, Kakinuma T, Jaber SH, Blauvelt A, Hwang ST
    J. Immunol., 2006;177(11):7665-72.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  166. Circulating cytokine/inhibitor profiles reshape the understanding of the SIRS/CARS continuum in sepsis and predict mortality.
    Authors: Osuchowski MF, Welch K, Siddiqui J, Remick DG
    J. Immunol., 2006;177(3):1967-74.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  167. An inflammation-induced mechanism for leukocyte transmigration across lymphatic vessel endothelium.
    Authors: Johnson LA, Clasper S, Holt AP, Lalor PF, Baban D, Jackson DG
    J. Exp. Med., 2006;203(12):2763-77.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  168. Noninvasive vascular cell adhesion molecule-1 imaging identifies inflammatory activation of cells in atherosclerosis.
    Authors: Nahrendorf M, Jaffer FA, Kelly KA, Sosnovik DE, Aikawa E, Libby P, Weissleder R
    Circulation, 2006;114(14):1504-11.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  169. Adenoviral-mediated overexpression of SOCS3 enhances IgG immune complex-induced acute lung injury.
    Authors: Gao H, Hoesel LM, Guo RF, Rancilio NJ, Sarma JV, Ward PA
    J. Immunol., 2006;177(1):612-20.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  170. TLR4 mediates vaccine-induced protective cellular immunity to Bordetella pertussis: role of IL-17-producing T cells.
    Authors: Higgins SC, Jarnicki AG, Lavelle EC, Mills KH
    J. Immunol., 2006;177(11):7980-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  171. TWEAK/Fn14 interaction regulates RANTES production, BMP-2-induced differentiation, and RANKL expression in mouse osteoblastic MC3T3-E1 cells.
    Authors: Ando T, Ichikawa J, Wako M, Hatsushika K, Watanabe Y, Sakuma M, Tasaka K, Ogawa H, Hamada Y, Yagita H, Nakao A
    Arthritis Res. Ther., 2006;8(5):R146.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  172. GM-CSF and the impaired pulmonary innate immune response following hyperoxic stress.
    Authors: Baleeiro CE, Christensen PJ, Morris SB, Mendez MP, Wilcoxen SE, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;291(6):L1246-55.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  173. Glechoma hederacea inhibits inflammatory mediator release in IFN-gamma and LPS-stimulated mouse peritoneal macrophages.
    Authors: An HJ, Jeong HJ, Um JY, Kim HM, Hong SH
    J Ethnopharmacol, 2006;106(3):418-24.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  174. Shedding of soluble ICAM-1 into the alveolar space in murine models of acute lung injury.
    Authors: Mendez MP, Morris SB, Wilcoxen S, Greeson E, Moore B, Paine R
    Am. J. Physiol. Lung Cell Mol. Physiol., 2006;290(5):L962-70.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  175. Overexpression of suppressor of cytokine signaling-5 in T cells augments innate immunity during septic peritonitis.
    Authors: Watanabe H, Kubo M, Numata K, Takagi K, Mizuta H, Okada S, Ito T, Matsukawa A
    J. Immunol., 2006;177(12):8650-7.
  176. Glatiramer acetate fights against Alzheimer's disease by inducing dendritic-like microglia expressing insulin-like growth factor 1.
    Authors: Butovsky O, Koronyo-Hamaoui M, Kunis G, Ophir E, Landa G, Cohen H, Schwartz M
    Proc. Natl. Acad. Sci. U.S.A., 2006;103(31):11784-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  177. Antiinflammatory effects of natural tetranortriterpenoids isolated from Carapa guianensis Aublet on zymosan-induced arthritis in mice.
    Authors: Penido C, Conte FP, Chagas MS, Rodrigues CA, Pereira JF, Henriques MG
    Inflamm. Res., 2006;55(11):457-64.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  178. Microglia activated by IL-4 or IFN-gamma differentially induce neurogenesis and oligodendrogenesis from adult stem/progenitor cells.
    Authors: Butovsky O, Ziv Y, Schwartz A, Landa G, Talpalar AE, Pluchino S, Martino G, Schwartz M
    Mol. Cell. Neurosci., 2006;31(1):149-60.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  179. Suppressive effect of simvastatin on interferon-beta-induced expression of CC chemokine ligand 5 in microglia.
    Authors: Nakamichi K, Saiki M, Kitani H, Kuboyama Y, Morimoto K, Takayama-Ito M, Kurane I
    Neurosci. Lett., 2006;407(3):205-10.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  180. Neutrophil recruitment in immunized mice depends on MIP-2 inducing the sequential release of MIP-1alpha, TNF-alpha and LTB(4).
    Authors: Ramos CD, Fernandes KS, Canetti C, Teixeira MM, Silva JS, Cunha FQ
    Eur. J. Immunol., 2006;36(8):2025-34.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  181. MyD88-dependent induction of allergic Th2 responses to intranasal antigen.
    Authors: Piggott DA, Eisenbarth SC, Xu L, Constant SL, Huleatt JW, Herrick CA, Bottomly K
    J. Clin. Invest., 2005;115(2):459-67.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  182. Sequential ELISA to profile multiple cytokines from small volumes.
    Authors: Osuchowski MF, Siddiqui J, Copeland S, Remick DG
    J. Immunol. Methods, 2005;302(1):172-81.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  183. Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload.
    Authors: Niederkofler V, Salie R, Arber S
    J. Clin. Invest., 2005;115(8):2180-6.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  184. Antibody-bound beta-amyloid precursor protein stimulates the production of tumor necrosis factor-alpha and monocyte chemoattractant protein-1 by cortical neurons.
    Authors: Gonzalez de Aguilar JL, Dupuis L, Larmet Y
    Neurobiol. Dis., 2005;19(1):129-41.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  185. Role for tumor necrosis factor alpha in murine cytomegalovirus transcriptional reactivation in latently infected lungs.
    Authors: Simon CO, Seckert CK, Dreis D, Reddehase MJ, Grzimek NK
    J. Virol., 2005;79(1):326-40.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  186. IL-1 mediates TNF-induced osteoclastogenesis.
    Authors: Wei S, Kitaura H, Zhou P, Ross FP, Teitelbaum SL
    J. Clin. Invest., 2005;115(2):282-90.
    Species: Human
    Sample Types: Whole Cells
    Applications: Bioassay
  187. IL-1 type I receptor plays a key role in mediating the recruitment of leukocytes into the central nervous system.
    Authors: Ching S, He L, Lai W, Quan N
    Brain Behav. Immun., 2005;19(2):127-37.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  188. Pivotal role of endogenous tachykinins and the NK1 receptor in mediating leukocyte accumulation, in the absence of oedema formation, in response to TNFalpha in the cutaneous microvasculature.
    Authors: Costa SK, Yshii LM, Poston RN, Muscara MN, Brain SD
    J. Neuroimmunol., 2005;171(1):99-109.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  189. Selective macrophage suppression during sepsis.
    Authors: Ellaban E, Bolgos G, Remick D
    Cell. Immunol., 2004;231(1):103-11.
    Species: N/A
    Sample Types: N/A
    Applications: ELISA (Standard)
  190. HIV-1 Tat increases the adhesion of monocytes and T-cells to the endothelium in vitro and in vivo: implications for AIDS-associated vasculopathy.
    Authors: Matzen K, Dirkx AE, oude Egbrink MG, Speth C, Gotte M, Ascherl G, Grimm T, Griffioen AW, Sturzl M
    Virus Res., 2004;104(2):145-55.
    Species: Mouse
    Sample Types: Interstitial Fluid
    Applications: Bioassay
  191. Thyrocytes isolated from autoimmune-diseased thyroids secrete soluble tumor necrosis factor-R1 that is related to their elevated protein kinase C activity.
    Authors: LaBue M, Colburn KK, Green LM
    Thyroid, 2004;14(4):249-62.
    Species: N/A
    Sample Types: N/A
    Applications: Western Blot
  192. T cell repertoire scanning is promoted by dynamic dendritic cell behavior and random T cell motility in the lymph node.
    Authors: Miller MJ, Hejazi AS, Wei SH, Cahalan MD, Parker I
    Proc. Natl. Acad. Sci. U.S.A., 2004;101(4):998-1003.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  193. Increased and long-term generation of dendritic cells with reduced function from IL-6-deficient bone marrow.
    Authors: Bleier JI, Pillarisetty VG, Shah AB, DeMatteo RP
    J. Immunol., 2004;172(12):7408-16.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  194. Mac-1, but not LFA-1, uses intercellular adhesion molecule-1 to mediate slow leukocyte rolling in TNF-alpha-induced inflammation.
    Authors: Dunne JL, Collins RG, Beaudet AL, Ballantyne CM, Ley K
    J. Immunol., 2003;171(11):6105-11.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  195. Novel docosatrienes and 17S-resolvins generated from docosahexaenoic acid in murine brain, human blood, and glial cells. Autacoids in anti-inflammation.
    Authors: Hong S, Gronert K, Devchand PR, Moussignac RL, Serhan CN
    J. Biol. Chem., 2003;278(17):14677-87.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  196. Endogenous granulocyte-macrophage colony-stimulating factor overexpression in vivo results in the long-term recruitment of a distinct dendritic cell population with enhanced immunostimulatory function.
    Authors: Miller G, Pillarisetty VG, Shah AB, Lahrs S, Xing Z, DeMatteo RP
    J. Immunol., 2002;169(6):2875-85.
    Species: Mouse
    Sample Types: Cell Culture Supernates
  197. Elevated levels of tumor necrosis factor alpha (TNF-alpha) in human immunodeficiency virus type 1-transgenic mice: prevention of death by antibody to TNF-alpha.
    Authors: De SK, Devadas K, Notkins AL
    J. Virol., 2002;76(22):11710-4.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  198. Modulation of marrow proliferation and chemosensitivity by tumor-produced cytokines from syngeneic pancreatic tumor lines.
    Authors: Blumenthal RD, Reising A, Leon E
    Clin. Cancer Res., 2002;8(5):1301-9.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  199. CD40 regulates the processing of NF-kappaB2 p100 to p52.
    Authors: Coope HJ, Atkinson PG, Huhse B, Belich M, Janzen J, Holman MJ, Klaus GG, Johnston LH, Ley SC
    EMBO J., 2002;21(20):5375-85.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay
  200. Hepatocyte-specific inhibition of NF-kappaB leads to apoptosis after TNF treatment, but not after partial hepatectomy.
    Authors: Chaisson ML, Brooling JT, Ladiges W, Tsai S, Fausto N
    J. Clin. Invest., 2002;110(2):193-202.
    Species: Mouse
    Sample Types: In Vivo
    Applications: In Vivo
  201. Inhibition of lipopolysaccharide-induced signal transduction in endotoxin-tolerized mouse macrophages: dysregulation of cytokine, chemokine, and toll-like receptor 2 and 4 gene expression.
    Authors: Medvedev AE, Kopydlowski KM, Vogel SN
    J. Immunol., 2000;164(11):5564-74.
    Species: Mouse
    Sample Types: Whole Cells
    Applications: Bioassay

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Recombinant Mouse TNF-alpha (aa 80-235) Protein
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Application: In vitro bioactivity in cell culture

Recombinant Mouse TNF-alpha (aa 80-235) Protein
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Application: In vitro bioactivity in cell culture

Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 05/23/2016
Application: Binding assay/Protein-protein interaction

Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 05/17/2016
Application: In vitro bioactivity in cell culture

Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 05/12/2016
Application: Mouse (C57BL/6) naïve, SPF, stimulated with recombinant mouse TNF-alpha protein.
Reason for Rating: Worked as expected.

Mouse (C57BL/6) naïve, SPF, stimulated with recombinant mouse TNF-alpha protein.


Recombinant Mouse TNF-alpha (aa 80-235) Protein
By Anonymous on 01/19/2016
Application: Immunoassay Standard