Total BDNF Quantikine ELISA Kit Summary
Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Platelet-poor EDTA Plasma, Heparin Plasma, Platelet-poor Heparin Plasma, Urine, Human Milk
|Intra-Assay Precision||Inter-Assay Precision|
The recovery of Total BDNF spiked to levels throughout the range of the assay in various matrices was evaluated.
|Sample Type||Average % Recovery||Range %|
|Cell Culture Media (n=4)||103||97-113|
|Cell Lysis Buffer (n=4)||94||87-100|
|Human Milk (n=4)||94||87-99|
|Platelet-poor EDTA Plasma (n=4)||95||76-110|
|Platelet-poor Heparin Plasma (n=4)||95||75-111|
Preparation and Storage
BDNF (Brain-Derived Neurotrophic Factor) is a secreted protein that regulates many aspects of neuronal development and function in the nervous system. It is produced as proBDNF in response to neuronal activity or inflammatory stimulation and is then cleaved before associating into a homodimer. It is expressed throughout the nervous system as well as by fibroblasts, megakaryocytes/platelets, and smooth muscle cells. BDNF regulates neural stem cell survival and differentiation, axon/dendrite differentiation, synapse formation and maturation, and refinement of developing circuits. It is also a key regulator of synaptic plasticity and late-phase long-term potentiation. BDNF signals through the TrkB and NGF R/TNFRSF16 receptors. Secreted proBDNF can bind to NGF R/TNFRSF16 and induce long-term depression and cell apoptosis.
No product specific FAQs exist for this product, however you mayView all ELISA FAQs
Supplemental ELISA Products
Reviews for Total BDNF Quantikine ELISA Kit
There are currently no reviews for this product. Be the first to review Total BDNF Quantikine ELISA Kit and earn rewards!
Have you used Total BDNF Quantikine ELISA Kit?
Submit a review and receive an Amazon gift card.
$25/€18/£15/$25CAN/¥75 Yuan/¥1250 Yen for a review with an image
$10/€7/£6/$10 CAD/¥70 Yuan/¥1110 Yen for a review without an image