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30 results for "alk-inhibitors&view=expanded" in Products

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SB 431542

Catalog #: 1614
(13)
Citations (2376)
Product Documents

Potent, selective inhibitor of TGF-βRI, ALK4 and ALK7

GMP Version Available: TB1614-GMP
GMP
Chemical Name: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity: ≥99%
dopaminergic neurons derived from hiPSCs using SB 431542
(2)

SB 431542 GMP

Catalog #: TB1614-GMP
Citations (2)
Product Documents

SB 431542 synthesized to cGMP guidelines

Chemical Name: 4-[4-(1,3-benzodioxol-5-yl)-5-(2-pyridinyl)-1H-imidazol-2-yl]benzamide
Purity: ≥99%
SB 431542 synthesized to cGMP guidelines

LDN 193189 dihydrochloride

Catalog #: 6053
(3)
Citations (153)
Product Documents

Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

GMP Version Available: TB6053-GMP
GMP
Alternate Names: LDN 193189 2HCl
Chemical Name: 4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity: ≥98%
Application of LDN 193189 in motor neurons differentiated from iPSCs
(2)

Dorsomorphin dihydrochloride

Catalog #: 3093
(3)
Citations (314)
Product Documents

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names: Compound C,BML-275
Chemical Name: 6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity: ≥98%
Potent AMPK inhibitor; also BMP type I receptor inhibitor

A 83-01

Catalog #: 2939
(12)
Citations (1077)
Product Documents

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name: 3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity: ≥98%
Adult Stem Cell-derived Liver Organoids
(6)

K 02288

Catalog #: 4986
Citations (13)
Product Documents

Type 1 BMP receptor inhibitor

Alternate Names: K 02288a
Chemical Name: 3-[(6-Amino-5-(3,4,5-trimethoxyphenyl)-3-pyridinyl]phenol
Purity: ≥98%
Type 1 BMP receptor inhibitor

RepSox

Catalog #: 3742
(1)
Citations (38)
Product Documents

Potent and selective inhibitor of TGF-βRI

Alternate Names: E-616452,SJN 2511,ALK5 Inhibitor II
Chemical Name: 2-[3-(6-Methylpyridin-2-yl)-1H-pyrazol-4-yl]-1,5-naphthyridine
Purity: ≥99%
Potent and selective inhibitor of TGF-βRI

SB 505124

Catalog #: 3263
Citations (61)
Product Documents

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name: 2-[4-(1,3-Benzodioxol-5-yl)-2-(1,1-dimethylethyl)-1H-imidazol-5-yl]-6-methyl-pyridine
Purity: ≥98%
Selective inhibitor of TGF-βRI, ALK4 and ALK7

ASP 3026

Catalog #: 5310
Citations (1)
Product Documents

Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor

Chemical Name: N2-[2-Methoxy-4-[4-(4-methyl-1-piperazinyl)-1-piperidinyl]phenyl]-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-1,3,5-triazine-2,4-diamine
Purity: ≥98%
Potent anaplastic lymphoma kinase (ALK) inhibitor; also potent ACK inhibitor

Ceritinib

Catalog #: 6905
Citations (1)
Product Documents

Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3

Alternate Names: LDK378
Chemical Name: 5-Chloro-N4-[2-[(1-methylethyl)sulfonyl]phenyl]-N2-[5-methyl-2-(1-methylethoxy)-4-(4-piperidinyl)phenyl]-2,4-pyrimidinediamine
Purity: ≥98%
Highly potent ALK inhibitor; also potently inhibits IR, IGF1R, STK22D and FLT3
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