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10 results for "BMP and Other Activin Receptor Inhibitors Small Molecules and Peptides" in Products

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BMP and Other Activin Receptor Inhibitors Small Molecules and Peptides

Activin receptors transduce signals carried by the TGF-β family of ligands. Such ligands include activin and bone morphogenetic proteins (BMPs). Members of this family are involved in a range of processes, including embryogenesis and tissue homeostasis.

Bone morphogenetic proteins (BMPs) are a group of growth factors belonging to the transforming growth factor-β (TGF-β) superfamily (excluding BMP1). Primarily characterized by their effects on bone and cartilage formation, ...

A 83-01

Catalog #: 2939

(12)

Citations (1068)

Product Documents

Selective inhibitor of TGF-βRI, ALK4 and ALK7

Chemical Name:	3-(6-Methyl-2-pyridinyl)-N-phenyl-4-(4-quinolinyl)-1H-pyrazole-1-carbothioamide
Purity:	≥98%

LDN 193189 dihydrochloride

Catalog #: 6053

(3)

Citations (131)

Product Documents

Potent and selective ALK2 and ALK3 inhibitor; inhibits BMP4 signaling; promotes neural induction of hPSCs

GMP Version Available: TB6053-GMP

GMP

Chemical Name:	4-[6-[4-(1-Piperazinyl)phenyl]pyrazolo[1,5-a]pyrimidin-3-yl]quinoline dihydrochloride
Purity:	≥98%

Dorsomorphin dihydrochloride

Catalog #: 3093

(3)

Citations (298)

Product Documents

Potent AMPK inhibitor; also BMP type I receptor inhibitor

Alternate Names:	Compound C,BML-275
Chemical Name:	6-[4-[2-(1-Piperidinyl)ethoxy]phenyl]-3-(4-pyridinyl)-pyrazolo[1,5-a]pyrimidine dihydrochloride
Purity:	≥98%