Histone Deacetylase 8/HDAC8: Products

Human Histone Deacetylase 8 (HDAC8) is a member of the class I histone Deacetylases (HDACs). Expression of HDAC8 is restricted to cells showing smooth muscle differentiation in normal human tissue and is a novel marker of smooth muscle differentiation.

Sirtuin 2, is a member of the class III histone deacetylases (HDACs) and has been implicated in many cellular processes that include histone deacetylation, gene silencing, chromosomal stability, and aging (3 - 4). The enzymatic activity of class III HDACs is nicotinamide adenine dinucleotide (NAD) dependent and insensitive to HDAC inhibitor trichostatin A

"Histone Deacetylase 8/HDAC8" has 6 results in Products.
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Class I and II HDAC inhibitor

PCI 34051 

Potent and selective HDAC8 inhibitor

CHDI 00390576 

Potent and selective class IIa HDAC inhibitor; brain penetrant
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