315 results for "Neutrophil Elastase/ELA2" in Products
Neutrophil Elastase/ELA2 Products
Neutrophil Elastase (ELA2), also known as polymorphonuclear leukocyte elastase, is a serine protease belonging to the chymotrypsin family. Located primarily in the azurophil granules of polymorphonuclear leukocytes, ELA2 function results in the degradation of many extracellular matrix macromolecules. Alpha-1 Antitrypsin (Serpin A1) and secretory leukocyte protease inhibitor (SLPI) have been shown to inhibit ELA2 activity. ELA2 may be involved in lung emphysema, cystic fibrosis, the adult respiratory distress syndrome (ARDS), rheumatoid arthritis, tumor invasion and infectious diseases.
| Reactivity: | Mouse |
| Sensitivity: | 3.37 pg/mL |
| Assay Range: | 31.3-2000 pg/mL (Cell Culture Supernates, Tissue Lysates, Serum, EDTA Plasma, Heparin Plasma) |
| Applications: | ELISA |
| Reactivity: | Human |
| Assay Range: | 46.9-3000 pg/mL |
| Applications: | ELISA |
| Reactivity: | Mouse |
| Assay Range: | 12.5-800 pg/mL |
| Applications: | ELISA |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #950317 |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #950334 |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
| Reactivity: | Mouse |
| Source: | NS0 |
| Accession #: | NP_056594 |
| Applications: | Enzyme Activity |
| Reactivity: | Human |
| Source: | CHO |
| Accession #: | P08246 |
| Applications: | Enzyme Activity |
Recombinant Monoclonal Antibody
| Reactivity: | Human, Mouse |
| Details: | Rabbit IgG Monoclonal Clone #JF098-6 |
| Applications: | IHC, WB, Flow, ICC/IF |
| Reactivity: | Mouse |
| Details: | Rat IgG2A Monoclonal Clone #887105 |
| Applications: | WB |
Recombinant Monoclonal Antibody.
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #950317R |
| Applications: | IHC, WB, Flow, ICC/IF, CyTOF-ready |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #950302 |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Mouse |
| Details: | Sheep IgG Polyclonal |
| Applications: | WB |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #950312 |
| Applications: | ELISA, Flow, CyTOF-ready |
| Reactivity: | Human, Monkey |
| Details: | Mouse IgG1 Monoclonal Clone #6B6B10 |
| Applications: | IHC, WB, ELISA, Flow |
| Reactivity: | Human, Rat |
| Details: | Mouse IgG1 Monoclonal Clone #6B6G6 |
| Applications: | WB, ELISA, Flow |
Selective leukocyte elastase inhibitor
| Alternate Names: | ONO-5046 |
| Chemical Name: | N-{2-[({4-[(2,2-Dimethylpropanoyl)oxy]phenyl}sulfonyl)amino]benzoyl}glycine sodium salt |
| Purity: | ≥98% |
Potent, orally active human leukocyte elastase inhibitor
| Chemical Name: | 2-[[6-Methoxy-4-(1-methylethyl)-1,1-dioxido-3-oxo-1,2-benzisothiazol-2(3H)-yl]methoxy]-9-[2-(1-piperidinyl)ethoxy]-4H-pyrido[1,2-a]pyrimidin-4-one |
| Purity: | ≥98% |
High affinity and selective human neutrophil elastase 1 (HNE1) inhibitor; orally active
| Chemical Name: | 5-Amino-N-[1-[[5-(1,1-dimethylethyl)-1,3,4-oxadiazol-2-yl]carbonyl]-2-methylpropyl]-6-oxo-2-phenyl-1(6H)-pyrimidineacetamide |
| Purity: | ≥98% |
Potent and selective cell-permeable human neutrophil elastase (HNE) inhibitor
| Chemical Name: | 5-[(4R)-5-Acetyl-1,2,3,4-tetrahydro-6-methyl-2-oxo-1-[3-(trifluoromethyl)phenyl]-4-pyrimidinyl]-2-pyridinecarbonitrile |
| Purity: | ≥98% |
Control for use with Human Neutrophil Elastase/ELA2 Simple Plex Assay Cartridge Kit
| Reactivity: | Human |
| Reactivity: | Human |
| Details: | Rabbit IgG Polyclonal |
| Applications: | IHC |
Simple Plex Human Neutrophil Elastase/ELA2 assay kit for use on Ella instrument. Contains a cartridge, Sample Diluent SD06, and Wash Buffer.
| Reactivity: | Human |
| Applications: | Simple Plex |
| Reactivity: | Human |
| Details: | Mouse IgG1 Monoclonal Clone #ELA10-101.5 (39A) |
| Applications: | ELISA, Flow, Func |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #950302 |
| Applications: | IHC, WB, ELISA, ICC/IF |
| Reactivity: | Human |
| Details: | Mouse IgG2A Monoclonal Clone #950302 |
| Applications: | IHC, WB, ELISA, ICC/IF |