15 results for "p38" in Products

p38 Products

The p38 Mitogen-activated Protein Kinases (MAPKs) are a family of four related Ser/Thr kinases activated by proinflammatory cytokines and environmental stresses. All four p38 family members, alpha, beta, gamma, and delta, are phosphorylated by MKK3 and/or MKK6 at dual Thr and Tyr positions within the phosphoacceptor sequence Thr-Gly-Tyr. Once activ...

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Contains 4 membranes - each spotted in duplicate with 26 different cell stress antibodies

Reactivity: Human
Applications:
Determination of Relative Levels of Selected Human Cell Stress-related Proteins.
(2)
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Selective inhibitor of p38 MAPK

Chemical Name: 4-[5-(4-Fluorophenyl)-2-[4-(methylsulfonyl)phenyl]-1H-imidazol-4-yl]pyridine
Purity: ≥98%
Selective inhibitor of p38 MAPK
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Potent, selective inhibitor of p38 MAPK

Chemical Name: 4-[4-(4-Fluorophenyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]phenol
Purity: ≥99%
iPSC-derived Human Intestinal Organoid
(4)
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JNK, SAPK and p38 activator

Chemical Name: (2R,3S,4S)-2-[(4-Methoxyphenyl)methyl]-3,4-pyrrolidinediol 3-acetate
Purity: ≥98%
JNK, SAPK and p38 activator
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High affinity and selective p38 kinase inhibitor

Alternate Names: Doramapimod
Chemical Name: N-[3-(1,1-Dimethylethyl)-1-(4-methylphenyl)-1H-pyrazol-5-yl]-N'-[4-[2-(4-morpholinyl)ethoxy]-1-naphthalenyl]urea
Purity: ≥98%
High affinity and selective p38 kinase inhibitor
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Selective inhibitor of p38 MAPK; water-soluble

Chemical Name: 4-[5-(4-Fluorophenyl)-2-[4-(methylsulphonyl)phenyl]-1H-imidazol-4-yl]pyridine hydrochloride
Purity: ≥98%
Selective inhibitor of p38 MAPK; water-soluble
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Potent, selective p38 MAPK inhibitor; orally active

Chemical Name: trans-4-[4-(4-Fluorophenyl)-5-(2-methoxy-4-pyrimidinyl)-1H-imidazol-1-yl]cyclohexanol
Purity: ≥98%
Potent, selective p38 MAPK inhibitor; orally active
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Selective p38 MAPK inhibitor

Chemical Name: 6-Chloro-5-[[(2R,5S)-4-[(4-fluorophenyl)methyl]-2,5-dimethyl-1-piperazinyl]carbonyl]-N,N,1-trimethyl-α-oxo-1H-Indole-3-acetamide hydrochloride
Purity: ≥98%
Selective p38 MAPK inhibitor
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p38 MAPK inhibitor

Chemical Name: N-Cyano-N'-[2-[[8-(2,6-difluorophenyl)-4-(4-fluoro-2-methylphenyl)-7,8-dihydro-7-oxopyrido[2,3-d]pyrimidin-2-yl]amino]ethyl]guanidine
Purity: ≥98%
p38 MAPK inhibitor
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p38 MAPK inhibitor; anti-inflammatory

Chemical Name: N-Cyclopropyl-4-[4-(4-fluorophenyl)-2-(4-piperidinyl)-5-thiazolyl]-2-pyrimidinamine dihydrochloride
Purity: ≥98%
p38 MAPK inhibitor; anti-inflammatory
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Potent p38 MAPK inhibitor; anti-inflammatory

Chemical Name: N-[4-[2-Ethyl-4-(3-methylphenyl)-5-thiazolyl]-2-pyridinyl]benzamide
Purity: ≥98%
Potent p38 MAPK inhibitor; anti-inflammatory
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Potent and selective p38α inhibitor

Alternate Names: VX745,VX-745,Neflamapimod
Chemical Name: 5-(2,6-Dichlorophenyl)-2-[2,4-difluorophenyl)thio]-6H-pyrimido[1,6-b]pyridazin-6-one
Purity: ≥98%
Potent and selective p38α inhibitor
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Selective inhibitor of p38α and p38β2

Chemical Name: (2-Methylphenyl)-[4-[(2-amino-4-bromophenyl)amino]-2-chlorophenyl]methanone
Purity: ≥98%
Selective inhibitor of p38α and p38β2
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Potent, selective p38α and p38β inhibitor

Chemical Name: 4-[4-(4-Fluorophenyl)-1-(3-phenylpropyl)-5-(4-pyridinyl)-1H-imidazol-2-yl]-3-butyn-1-ol
Purity: ≥98%
Potent, selective p38α and p38β inhibitor
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Potent and selective p38α/β inhibitor

Chemical Name: (-)-3-[3-Bromo-4-[(2,4-difluorophenyl)methoxy]-6-methyl-2-oxo-1(2H)-pyridinyl]-N,4-dimethylbenzamide
Purity: ≥98%
Potent and selective p38α/β inhibitor
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